Independent significant predictors of a higher score in Hamilton Depression (HAM-D) (depression screening).

Rasch analysis of HDRS-17.

The global surge in depression rates, notably severe in China with over 95 million affected, underscores a dire public health issue. This is exacerbated by a critical shortfall in mental health professionals, highlighting an urgent call for innovative approaches. The advancement of Artificial Intelligence (AI), particularly Large Language Models, offers a promising solution by improving mental health diagnostics. However, there is a lack of real data for reliable training and accurate evaluation of AI models. To this end, this paper presents a high-quality multimodal depression consultation dataset, namely Parallel Data of Depression Consultation and Hamilton Depression Rating Scale (PDCH). The dataset is constructed based on clinical consultations from Beijing Anding Hospital, which provides audio recording and transcribed text, as well as corresponding HAMD-17 scales annotated by professionals. The dataset contains 100 consultations and the audio exceeds 2,937 minutes.Each of them is about 30-min long with more than 150 dialogue turns. It enables to fill the gap in mental health services and benefit the creation of more accurate AI models.

Multiple linear regression analyses of Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Rating Scale (HAMA) scores.

Outcomes after 2, 4 and 6 weeks: mean differences and confidence intervals of pooled groups (HAM-D = Hamilton Depression Scale values <0 favor homeopathy or case history I, BDI = Beck Depression Inventory values <0 favor homeopathy or case history I, SF-12 = short form 12 health related quality of life questionnaire values >0 favor homeopathy or case history I).

All reported depression outcomes were assessed at the end of the treatment period except MIND-IT [33] where depression outcomes were assessed 18 months post-myocardial infarction (0–9 months after completion of treatment).†Cardiovascular serious adverse events = myocardial infarction, congestive heart failure, worsening angina, stroke, or other cardiovascular events.‡Of the 2,481 randomized patients in the ENRICHD trial who met eligibility criteria for MDD, minor depression, or dysthymia and/or low social support [31], data are reported only for the subset of 955 randomized patients diagnosed with MDD. Original data for the ENRICHD trial were obtained from the National Heart Lung and Blood Institute.§In the depression outcome analyses presented, the last-observation-carried-forward approach was applied for missing data. The original published report of the ENRICHD trial [31] reported outcome data for completers. Based on completer data only, Δ HAMD-17: Hedges' g = 0.24, 95% CI 0.09 to 0.39 (N = 690, CBT: 348, UC: 342). Δ BDI: Hedges' g = 0.36, 95% CI 0.21 to 0.51 (N = 699, CBT: 357, UC: 342).∥The Honig, 2007 [32] study was an RCT nested within the MIND-IT study [33].¶Total cardiac events include cardiac death, recurrent myocardial infarction, revascularization, heart failure, myocardial ischemia, and ventricular arrhythmia. 17 patients were lost to follow-up (Tx, n = 196; UC, n = 118).#Patients were assessed with HAMD-17 at 16 weeks, but not 24 weeks.*Major adverse cardiac events = events involving death or requiring hospitalization.††Hazard ratio from Kaplan-Meier analysis, but number of deaths per group not provided for follow-up study (Glassman AH, Bigger JT,Jr, Gaffney M. Psychiatric characteristics associated with long-term mortality among 361 patients having an acute coronary syndrome and major depression: Seven-year follow-up of SADHART participants. Arch Gen Psychiatry. 2009 Sep;66:1022–9). BDI = Beck Depression Inventory; BDI-II = Beck Depression Inventory – II; CBT = cognitive behavior therapy; CM = clinical management; CGI-I = Clinical Global Impression-Improvement; CGI-S = Clinical Global Impression-Severity; CI = confidence interval; CREATE = Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy trial; ENRICHD = Enhancing Recovery in Coronary Heart Disease Patients; HAMD-17 = 17-item Hamilton Depression Rating Scale; HAMD-24 = 24-item Hamilton Depression Rating Scale; HAMD-31 = 31-item Hamilton Depression Rating Scale; IPT = interpersonal therapy; MADRS = Montgomery-Asberg Depression Rating Scale; MI = myocardial infarction; MIND-IT = Myocardial Infarction and Depression-Intervention trial; NA = not applicable; SADHART = Sertraline Antidepressant Heart Attack Randomized trial; SADHART-CHF = Sertraline Against Depression and Heart Disease in Chronic Heart Failure; SCL-90-D = depression subscale of the Symptom Checklist 90; Tx = treatment; UC = usual care.

Serum markers in patients with and without depression.

Results of screening for anxiety and depression using the Hamilton anxiety (HAM-A) and depression (HAM-D) tools (N-192).

DSM-IV  =  Diagnostic and Statistical Manual of Mental Disorders (fourth edition), DSM-III-R  =  Diagnostic and Statistical Manual of Mental Disorders (third edition, revised), MADRS  =  Montgomery-Asberg Depression Scale, HAM-D  =  Hamilton Depression Inventory, IDS-C  =  Inventory of Depressive Symptomatology-Clinician.

HAMD: Hamilton depression scale; HAMA: Hamilton anxiety scale; SCL-90: Symptom Check List-90.aThe p value for gender distribution in the two groups was obtained by chi-square test.bThe p values were obtained by two sample t-tests.

Pearson correlates between positive affect scores, negative affect scores and hamilton anxiety and depression scale scores.

Clinical demographics of Graves’ disease patients.

Yearly citation counts for the publication titled "The Hamilton Rating Scales for Depression: A Critical Review of Clinimetric Properties of Different Versions".

a: information for one subject was lostb: family history of depressive disorder up to second-degree relativesHAMD, Hamilton Depression Scale; MDD, major depressive disorder; NA, not applicableDemographic and clinical characteristics of the study samples.

Legend: HAM, 17-item Hamilton Depression Rating Scale; BDI, 21-item Beck Depression Inventory; CORE, Core Assessment of Psychomotor change. The items that did not enter the models by Uher and Parker are coded in the “none” item dimension category.Exploratory Factor Analysis six-factor solution.

The dataset used in the paper is a clinical trial data, specifically the Hamilton Rating Scale for Depression (HAM-D) scores for patients with major depressive disorder.

HDRS: Hamilton Depression Rating Scale total score, SD: standard variation.

MDD, major depressive disorder; SD, standard deviation; HDRS, Hamilton Depression Rating Scale; HARS, Hamilton Anxiety Rating Scale.Subject Demographic and Clinical Data.

MDD: major depressive disorder.SD = standard deviation.MWT-B: Multiple-choice vocabulary test.HDRS: Hamilton Depression Rating Scale.BDI: Beck's Depression Inventory.* Group differences were computed using independent sample t-test for continuous and Chi-square-test for categorial variables. The level of statistical significance was set at p<0.05.