100+ datasets found
  1. N

    Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries

    • datacatalog.med.nyu.edu
    Updated Jun 16, 2025
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    Silvana Valtcheva; Habon A. Issa; Chloe J. Bair-Marshall; Kathleen A. Martin; Kanghoon Jung; Yiyao Zhang; Hyung-Bae Kwon; Robert C. Froemke (2025). Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries [Dataset]. http://doi.org/10.5281/zenodo.8060338
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    Dataset updated
    Jun 16, 2025
    Dataset provided by
    NYU Health Sciences Library
    Authors
    Silvana Valtcheva; Habon A. Issa; Chloe J. Bair-Marshall; Kathleen A. Martin; Kanghoon Jung; Yiyao Zhang; Hyung-Bae Kwon; Robert C. Froemke
    Description

    Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This study describes a neural circuit routing auditory information about infant vocalizations to mouse oxytocin neurons. They performed in vivo electrophysiological recordings and photometry from identified oxytocin neurons in awake maternal mice presented with pup calls. For this study, they made cell-attached and whole-cell recordings from PVN oxytocin neurons and other optically-unresponsive PVN neurons in awake head-fixed mouse dams. The dataset contains electrophysiology, behavioral, histology, and fiber photometry data. This study reveals a circuit that unlocks central oxytocin release and maternal behavior in response to pup calls.

  2. H

    Oxytocin Market Report - Demand, Trends & Forecast 2025 to 2035

    • futuremarketinsights.com
    html, pdf
    Updated Jan 9, 2025
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    Future Market Insights (2025). Oxytocin Market Report - Demand, Trends & Forecast 2025 to 2035 [Dataset]. https://www.futuremarketinsights.com/reports/oxytocin-market
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    html, pdfAvailable download formats
    Dataset updated
    Jan 9, 2025
    Dataset authored and provided by
    Future Market Insights
    License

    https://www.futuremarketinsights.com/privacy-policyhttps://www.futuremarketinsights.com/privacy-policy

    Time period covered
    2025 - 2035
    Area covered
    Worldwide
    Description

    The global sales of oxytocin are estimated to be worth USD 108.4 million in 2025 and are anticipated to reach a value of USD 245.7 million by 2035. Sales are projected to rise at a CAGR of 8.3% over the forecast period between 2025 and 2035. The revenue generated by oxytocin in 2024 was USD 99.2 million.

    AttributesKey Insights
    Historical Size, 2024USD 99.2 million
    Estimated Size, 2025USD 108.4 million
    Projected Size, 2035USD 245.7 million
    Value-based CAGR (2025 to 2035)8.3%

    Semi Annual Market Update

    ParticularValue CAGR
    H19.0% (2024 to 2034)
    H28.7% (2024 to 2034)
    H18.3% (2025 to 2035)
    H27.8% (2025 to 2035)

    Country-wise Insights

    CountriesValue CAGR (2025 to 2035)
    USA3.1%
    Germany2.7%
    UK6.3%
    Spain4.5%
    China9.2%
    India9.9%

    Category-wise Insights

    Product TypePostpartum
    Value Share (2025)87.6%
    By Distribution ChannelHospital Pharmacies
    Value Share (2025)64.5%
  3. N

    Data from: Oxytocin reduces neural activation in response to infant faces in...

    • neurovault.org
    zip
    Updated Sep 11, 2018
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    (2018). Oxytocin reduces neural activation in response to infant faces in nulliparous young women [Dataset]. http://identifiers.org/neurovault.collection:3699
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    zipAvailable download formats
    Dataset updated
    Sep 11, 2018
    License

    CC0 1.0 Universal Public Domain Dedicationhttps://creativecommons.org/publicdomain/zero/1.0/
    License information was derived automatically

    Description

    A collection of 3 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

    Collection description

  4. Oxytocin Market Size, Share Analysis & Growth Research Report, 2030

    • mordorintelligence.com
    pdf,excel,csv,ppt
    Updated Jul 7, 2025
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    Mordor Intelligence (2025). Oxytocin Market Size, Share Analysis & Growth Research Report, 2030 [Dataset]. https://www.mordorintelligence.com/industry-reports/oxytocin-market
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    pdf,excel,csv,pptAvailable download formats
    Dataset updated
    Jul 7, 2025
    Dataset authored and provided by
    Mordor Intelligence
    License

    https://www.mordorintelligence.com/privacy-policyhttps://www.mordorintelligence.com/privacy-policy

    Time period covered
    2019 - 2030
    Area covered
    Global
    Description

    The Oxytocin Market Report is Segmented by Indication (Antepartum, Postpartum), Route of Administration (Parenteral, Intranasal, Oromucosal), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, South America). The Market Forecasts are Provided in Terms of Value (USD).

  5. Detailed oxytocin protocol in each study.

    • plos.figshare.com
    • datasetcatalog.nlm.nih.gov
    xls
    Updated Jun 2, 2023
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    Danni Jiang; Yang Yang; Xinxin Zhang; Xiaocui Nie (2023). Detailed oxytocin protocol in each study. [Dataset]. http://doi.org/10.1371/journal.pone.0267461.t002
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    xlsAvailable download formats
    Dataset updated
    Jun 2, 2023
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Danni Jiang; Yang Yang; Xinxin Zhang; Xiaocui Nie
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    Detailed oxytocin protocol in each study.

  6. D

    Data from: Data belonging to: The oxytocin effect on empathy and emotion...

    • ssh.datastations.nl
    Updated Nov 3, 2020
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    I. Fragkaki; M.J. Cima; I. Fragkaki; M.J. Cima (2020). Data belonging to: The oxytocin effect on empathy and emotion recognition in residential youth: A randomized, within-subjects trial. [Dataset]. http://doi.org/10.17026/DANS-XGY-4DYJ
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    xml(4576), tsv(52982), text/x-fixed-field(917631), pdf(55209), pdf(167544), tsv(797803), pdf(71855), zip(21766), text/x-fixed-field(47668), pdf(66086), tsv(797177), txt(1562), tsv(51100), application/x-spss-syntax(4345), application/x-spss-syntax(4619)Available download formats
    Dataset updated
    Nov 3, 2020
    Dataset provided by
    DANS Data Station Social Sciences and Humanities
    Authors
    I. Fragkaki; M.J. Cima; I. Fragkaki; M.J. Cima
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    The dataset contains the files (DARE_Workfile, Empathy_Workfile) used for the analyses of the study published by Fragkaki and Cima (2019) in Psychoneuroendocrinology. The study examined the effect of oxytocin administration on empathy and emotion recognition in 100 male adolescents living in residential youth care facilities. The study had a randomized, double-blind, placebo-controlled, within-subject design. The study included 3 sessions: screening session and two experimental sessions. In the experimental sessions, the participants received oxytocin in one session and placebo in the other session and performed the same experimental tasks on empathy and emotion recognition 30 min after administration. The order of the sprays as well as the order of the tasks were randomized using computer randomization. We performed mixed modeling to examined the effect of oxytocin on the outcome variables. The file “Documentation-ReadMe” describes the trial information, methodology, and the variables included in the datasets. The file "icu_dutch" is the Dutch version of the Inventory of callous-unemotional traits, the file ctq_dutch" is the Dutch version of the Childhood trauma questionnaire", and the file "ades_dutch" is the Dutch version of the Adolescent dissociative experiences scale.

  7. N

    Data from: Oxytocin and brain activity in humans: A systematic review and...

    • neurovault.org
    zip
    Updated Jun 30, 2018
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    (2018). Oxytocin and brain activity in humans: A systematic review and coordinate-based meta-analysis of functional MRI studies [Dataset]. http://identifiers.org/neurovault.collection:3713
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    zipAvailable download formats
    Dataset updated
    Jun 30, 2018
    License

    CC0 1.0 Universal Public Domain Dedicationhttps://creativecommons.org/publicdomain/zero/1.0/
    License information was derived automatically

    Description

    A collection of 60 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

    Collection description

    We employed a coordinate-based meta-analysis for task-based neuroimaging literature using activation likelihood estimation (ALE), whereby, coordinates were extracted from clusters with significant differences in intranasal oxytocin versus placebo in healthy adults. Data were included for 39 fMRI studies that reported a total of 372 distinct foci in 1568 participants.

  8. H

    Oxytocin Testing Kits Market Analysis - Size, Share, and Forecast Outlook...

    • futuremarketinsights.com
    html, pdf
    Updated Jul 21, 2025
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    Future Market Insights (2025). Oxytocin Testing Kits Market Analysis - Size, Share, and Forecast Outlook 2025 to 2035 [Dataset]. https://www.futuremarketinsights.com/reports/oxytocin-testing-kits-market
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    pdf, htmlAvailable download formats
    Dataset updated
    Jul 21, 2025
    Dataset authored and provided by
    Future Market Insights
    License

    https://www.futuremarketinsights.com/privacy-policyhttps://www.futuremarketinsights.com/privacy-policy

    Time period covered
    2025 - 2035
    Area covered
    Worldwide
    Description

    The global oxytocin testing kits market is anticipated to reach USD 1,351.4 million by 2035, rising from USD 740.5 million in 2025 at a 6.2% CAGR.

    AttributeValue
    Market Size in 2025USD 740.5 million
    Market Size in 2035USD 1,351.4 million
    CAGR (2025 to 2035)6.2%

    Top Countries Manufacturing, Distributing, and Scaling Oxytocin Testing Kits

    CountriesCAGR (2025 to 2035)
    United States5.2%
    Germany5.8%
    China8.9%
    Japan4.4%
    India10.3%
  9. e

    Affectionate touch and diurnal oxytocin levels: An ecological momentary...

    • b2find.eudat.eu
    Updated Dec 10, 2023
    + more versions
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    (2023). Affectionate touch and diurnal oxytocin levels: An ecological momentary assessment study [Research Data] - Dataset - B2FIND [Dataset]. https://b2find.eudat.eu/dataset/3a7e5340-7241-5ac4-98d2-291ae3a7b354
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    Dataset updated
    Dec 10, 2023
    Description

    Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

  10. f

    Demographic data, illness characteristics, basal and induced oxytocin levels...

    • datasetcatalog.nlm.nih.gov
    • plos.figshare.com
    Updated Apr 7, 2020
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    Schöner, Johanna; Rentzsch, Johannes; Speck, Lucas Guilherme; Gallinat, Jürgen; Majić, Tomislav; Montag, Christiane; Just, Sandra; Stuke, Frauke (2020). Demographic data, illness characteristics, basal and induced oxytocin levels and dimensions of empathy in patients with schizophrenia and healthy controls. [Dataset]. https://datasetcatalog.nlm.nih.gov/dataset?q=0000492590
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    Dataset updated
    Apr 7, 2020
    Authors
    Schöner, Johanna; Rentzsch, Johannes; Speck, Lucas Guilherme; Gallinat, Jürgen; Majić, Tomislav; Montag, Christiane; Just, Sandra; Stuke, Frauke
    Description

    Demographic data, illness characteristics, basal and induced oxytocin levels and dimensions of empathy in patients with schizophrenia and healthy controls.

  11. f

    DataSheet1_Transcriptional diversity of the oxytocin receptor in prairie...

    • datasetcatalog.nlm.nih.gov
    • frontiersin.figshare.com
    Updated Aug 29, 2023
    + more versions
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    Page, Emma A.; Connelly, Jessica J.; Kenkel, William M.; Danoff, Joshua S.; Yee, Jason R.; Carter, C. Sue; Perkeybile, Allison M.; Ferris, Craig F. (2023). DataSheet1_Transcriptional diversity of the oxytocin receptor in prairie voles: mechanistic implications for behavioral neuroscience and maternal physiology.docx [Dataset]. https://datasetcatalog.nlm.nih.gov/dataset?q=0000961154
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    Dataset updated
    Aug 29, 2023
    Authors
    Page, Emma A.; Connelly, Jessica J.; Kenkel, William M.; Danoff, Joshua S.; Yee, Jason R.; Carter, C. Sue; Perkeybile, Allison M.; Ferris, Craig F.
    Description

    The neurohormone oxytocin regulates many aspects of physiology primarily by binding to its receptor, the oxytocin receptor. The oxytocin receptor gene (Oxtr) has been shown to have alternative transcripts in the mouse brain which may each have different biological functions or be used in specific contexts. A popular animal model for studying oxytocin-dependent social behaviors is the prairie vole, a biparental and monogamous rodent. Alternative transcriptional capacity of Oxtr in prairie voles is unknown. We used 5′ rapid amplification of cDNA ends to identify alternative Oxtr transcription start sites in prairie vole brain tissue and uterine tissue. We then validated expression of specific transcripts in fetal brains and assessed the impact of exogenous oxytocin administration in utero on offspring brain development. We identified seven distinct Oxtr transcripts, all of which are present in both brain and uterine tissue. We then demonstrated that maternal oxytocin administration alters expression of a specific subset of Oxtr transcripts and that these different transcripts are under unique epigenetic regulation, such that in the perinatal period only one of the alternative transcripts is associated with DNA methylation in the Oxtr promoter. These data establish the existence of multiple Oxtr transcripts in prairie vole brain and uterine tissue and implicate oxytocin in the regulation of alternative transcript expression. These data have significant implications for our understanding of null mutant models in both mice and voles and translation in human birth and behavior.

  12. D

    Oxytocin Market Report | Global Forecast From 2025 To 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Jan 7, 2025
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    Dataintelo (2025). Oxytocin Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/global-oxytocin-market
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    pdf, pptx, csvAvailable download formats
    Dataset updated
    Jan 7, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Oxytocin Market Outlook



    The global oxytocin market size was estimated at USD 173.5 million in 2023 and is projected to reach a valuation of approximately USD 257.4 million by 2032, growing at a compound annual growth rate (CAGR) of 4.5% during the forecast period from 2024 to 2032. This expansion is primarily driven by the increasing demand for oxytocin in various medical applications, especially in obstetrics, due to its critical role in labor induction and management of postpartum hemorrhage. The rising awareness and education about maternal health, coupled with technological advancements in healthcare, are key factors that are likely to positively impact the growth trajectory of the oxytocin market over the coming years.



    The growth of the oxytocin market is largely fueled by the increasing global birth rate and the subsequent demand for effective labor induction methods. As more women seek medical assistance during childbirth, the usage of oxytocin for labor induction has seen a significant rise. This trend is further bolstered by the availability of improved healthcare infrastructure and medical personnel trained in handling childbirth procedures efficiently across various developing regions. Additionally, the increasing awareness about maternal and neonatal health prompts healthcare providers to adopt best practices in labor management, where oxytocin plays an indispensable role, thereby driving market growth.



    Another growth factor contributing to the oxytocin market is the rising incidence of postpartum hemorrhage, a major cause of maternal mortality worldwide. The use of oxytocin as a uterotonic agent to control bleeding after delivery has made it an essential drug in maternity care settings. Governments and health organizations are actively promoting the use of oxytocin as a preventive measure against postpartum hemorrhage, further boosting its demand. Initiatives to enhance maternal health and reduce childbirth-related complications are crucial in ensuring the wide adoption of oxytocin, particularly in regions with high maternal mortality rates.



    In addition to its role in labor management, oxytocin is also gaining recognition for its potential benefits in lactation enhancement. The hormone stimulates milk ejection in breastfeeding mothers, helping to improve breastfeeding rates and infant nutrition. With the rising emphasis on breastfeeding and infant health, the demand for oxytocin to support lactation is expected to increase, contributing to market growth. Furthermore, the ongoing research into the broader therapeutic applications of oxytocin, such as its use in treating certain psychiatric conditions, could open new avenues for market expansion.



    Carbetocin Injection is emerging as a promising alternative to oxytocin in the management of postpartum hemorrhage, particularly in settings where cold chain storage is a challenge. Unlike oxytocin, Carbetocin Injection does not require refrigeration, making it highly suitable for use in low-resource settings where maintaining a cold chain is difficult. This stability under ambient conditions allows for broader distribution and accessibility, especially in rural and remote areas. Moreover, clinical studies have shown that Carbetocin Injection is as effective as oxytocin in preventing postpartum hemorrhage, offering a viable option for healthcare providers. As global health initiatives continue to focus on reducing maternal mortality, the adoption of Carbetocin Injection could play a critical role in enhancing maternal health outcomes, particularly in developing regions.



    From a regional perspective, the oxytocin market is witnessing varied growth patterns. North America and Europe are prominent markets due to their advanced healthcare systems and high awareness of maternal health issues. Meanwhile, the Asia Pacific region is anticipated to exhibit the fastest growth during the forecast period, driven by a substantial rise in birth rates and improving healthcare facilities. The Middle East & Africa and Latin America are also emerging as significant markets due to increasing healthcare investments and initiatives aimed at reducing maternal mortality. Overall, the global oxytocin market is poised for steady growth, supported by multiple regional dynamics and healthcare trends.



    Product Type Analysis



    Within the oxytocin market, the segmentation by product type into synthetic and natural oxytocin presents a comprehensive landscape of choices available to healthcare providers. Synthetic oxy

  13. m

    Global Injection Oxytocin Manufacturers Profiles Market Share, Size &...

    • marketresearchintellect.com
    Updated Aug 15, 2025
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    Market Research Intellect (2025). Global Injection Oxytocin Manufacturers Profiles Market Share, Size & Industry Analysis 2033 [Dataset]. https://www.marketresearchintellect.com/product/global-injection-oxytocin-manufacturers-profiles-market-size-and-forecast/
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    Dataset updated
    Aug 15, 2025
    Dataset authored and provided by
    Market Research Intellect
    License

    https://www.marketresearchintellect.com/privacy-policyhttps://www.marketresearchintellect.com/privacy-policy

    Area covered
    Global
    Description

    Explore insights from Market Research Intellect's Injection Oxytocin Manufacturers Profiles Market Report, valued at USD 1. 5 billion in 2024, expected to reach USD 2. 5 billion by 2033 with a CAGR of 7. 5% during 2026–2033. Uncover opportunities across demand patterns, technological innovations, and market leaders.

  14. n

    Oxytocin Attenuates Microglial Activation and Restores Social and Non-Social...

    • datacatalog.med.nyu.edu
    Updated Nov 16, 2022
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    (2022). Oxytocin Attenuates Microglial Activation and Restores Social and Non-Social Memory in APP/PS1 Mice [Dataset]. https://datacatalog.med.nyu.edu/search?keyword=subject_keywords:Microglia
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    Dataset updated
    Nov 16, 2022
    Description

    This study examined oxytocin expression in experimental models of Alzheimer’s disease (AD), and evaluated the therapeutic potential of treatment with oxytocin. They investigated changes in oxytocin expression in APP/PS1 mouse model and developed a chronic intranasal treatment protocol to increase oxytocin levels in the brain. Then, tested oxytocin as a potential approach to attenuate microglial activation and reverse memory deficits. This dataset includes source data used to assemble different figures in the publication. The source data contains data about hypothalamic expression of oxytocin is reduced in AD models, chronic intranasal administration of oxytocin increases hippocampal oxytocin and attenuates fear response in mice, cellular and molecular impact of intranasal oxytocin in APP/PS1 mouse brains, oxytocin attenuates AβO-induced microglial activation in vitro, and intranasal oxytocin reverses social and non-social memory deficits in aged APP/PS1 mice.

  15. d

    Institutional Oxytocin Checklist

    • dataone.org
    • borealisdata.ca
    Updated Dec 28, 2023
    + more versions
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    Dana Vitner, Hayley Lipworth, Eran Weiner, Maayan Bas Lnado, Andrea Page, Nir Melamed & Jon Barrett (2023). Institutional Oxytocin Checklist [Dataset]. http://doi.org/10.5683/SP3/ZKHGN0
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    Dataset updated
    Dec 28, 2023
    Dataset provided by
    Borealis
    Authors
    Dana Vitner, Hayley Lipworth, Eran Weiner, Maayan Bas Lnado, Andrea Page, Nir Melamed & Jon Barrett
    Description

    The implementation of an institutional oxytocin checklist did not affect expert assessment of the use of oxytocin in labor. Checklist is included within the publication's appendix.

  16. O

    Oxytocin Supplement Report

    • datainsightsmarket.com
    doc, pdf, ppt
    Updated Jan 2, 2025
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    Data Insights Market (2025). Oxytocin Supplement Report [Dataset]. https://www.datainsightsmarket.com/reports/oxytocin-supplement-1167841
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    pdf, ppt, docAvailable download formats
    Dataset updated
    Jan 2, 2025
    Dataset authored and provided by
    Data Insights Market
    License

    https://www.datainsightsmarket.com/privacy-policyhttps://www.datainsightsmarket.com/privacy-policy

    Time period covered
    2025 - 2033
    Area covered
    Global
    Variables measured
    Market Size
    Description

    The global Oxytocin Supplement market is projected to reach a value of $90 million by 2033, expanding at a CAGR of 7.9% from 2025 to 2033. The increasing prevalence of mental health disorders, such as anxiety, depression, and autism, is driving the demand for oxytocin supplements as these supplements have been shown to have therapeutic effects in reducing symptoms of these conditions. Additionally, the growing awareness about the benefits of oxytocin, such as its role in promoting social bonding and reducing stress, is contributing to the market growth. Geographical segmentation reveals that North America holds the dominant share in the Oxytocin Supplement market, owing to the high prevalence of mental health disorders and the presence of major pharmaceutical companies in the region. Asia Pacific is expected to witness significant growth over the forecast period due to rising healthcare expenditure, increasing awareness about mental health, and the presence of a large population base. Key players in the market include PherLuv, Green Organic Supplements, CareFirst Pharmacy, Super Nature Products, BeringOmega, and Empower Pharmacy Market Outlook The global oxytocin supplement market is poised to witness substantial growth, with an estimated value of over USD 500 million by 2028. This surge is attributed to the increasing prevalence of hormone imbalances, social isolation, and mental health issues, driving the demand for oxytocin as a natural remedy.

  17. f

    Effects of oxytocin administration and conditioned oxytocin on brain...

    • plos.figshare.com
    • datasetcatalog.nlm.nih.gov
    tiff
    Updated May 31, 2023
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    Aleksandrina Skvortsova; Dieuwke S. Veldhuijzen; Mischa de Rover; Gustavo Pacheco-Lopez; Marian Bakermans-Kranenburg; Marinus van IJzendoorn; Niels H. Chavannes; Henriët van Middendorp; Andrea W. M. Evers (2023). Effects of oxytocin administration and conditioned oxytocin on brain activity: An fMRI study [Dataset]. http://doi.org/10.1371/journal.pone.0229692
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    tiffAvailable download formats
    Dataset updated
    May 31, 2023
    Dataset provided by
    PLOS ONE
    Authors
    Aleksandrina Skvortsova; Dieuwke S. Veldhuijzen; Mischa de Rover; Gustavo Pacheco-Lopez; Marian Bakermans-Kranenburg; Marinus van IJzendoorn; Niels H. Chavannes; Henriët van Middendorp; Andrea W. M. Evers
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    It has been demonstrated that secretion of several hormones can be classically conditioned, however, the underlying brain responses of such conditioning have never been investigated before. In this study we aimed to investigate how oxytocin administration and classically conditioned oxytocin influence brain responses. In total, 88 females were allocated to one of three groups: oxytocin administration, conditioned oxytocin, or placebo, and underwent an experiment consisting of three acquisition and three evocation days. Participants in the conditioned group received 24 IU of oxytocin together with a conditioned stimulus (CS) during three acquisition days and placebo with the CS on three evocation days. The oxytocin administration group received 24 IU of oxytocin and the placebo group received placebo during all days. On the last evocation day, fMRI scanning was performed for all participants during three tasks previously shown to be affected by oxytocin: presentation of emotional faces, crying baby sounds and heat pain. Region of interest analysis revealed that there was significantly lower activation in the right amygdala and in two clusters in the left superior temporal gyrus in the oxytocin administration group compared to the placebo group in response to observing fearful faces. The activation in the conditioned oxytocin group was in between the other two groups for these clusters but did not significantly differ from either group. No group differences were found in the other tasks. Preliminary evidence was found for brain activation of a conditioned oxytocin response; however, despite this trend in the expected direction, the conditioned group did not significantly differ from other groups. Future research should, therefore, investigate the optimal timing of conditioned endocrine responses and study whether the findings generalize to other hormones as well.

  18. Spearman correlation coefficients for associations between basal / induced...

    • plos.figshare.com
    • datasetcatalog.nlm.nih.gov
    xls
    Updated Jun 5, 2023
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    Christiane Montag; Johanna Schöner; Lucas Guilherme Speck; Sandra Just; Frauke Stuke; Johannes Rentzsch; Jürgen Gallinat; Tomislav Majić (2023). Spearman correlation coefficients for associations between basal / induced oxytocin levels and MET cognitive and emotional empathy in patients with schizophrenia and healthy controls. [Dataset]. http://doi.org/10.1371/journal.pone.0231257.t002
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    xlsAvailable download formats
    Dataset updated
    Jun 5, 2023
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Christiane Montag; Johanna Schöner; Lucas Guilherme Speck; Sandra Just; Frauke Stuke; Johannes Rentzsch; Jürgen Gallinat; Tomislav Majić
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    Spearman correlation coefficients for associations between basal / induced oxytocin levels and MET cognitive and emotional empathy in patients with schizophrenia and healthy controls.

  19. v

    Oxytocin Market Size, Share & Growth Report, 2033

    • valuemarketresearch.com
    Updated Jan 24, 2024
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    Value Market Research (2024). Oxytocin Market Size, Share & Growth Report, 2033 [Dataset]. https://www.valuemarketresearch.com/report/oxytocin-market
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    electronic (pdf), ms excelAvailable download formats
    Dataset updated
    Jan 24, 2024
    Dataset authored and provided by
    Value Market Research
    License

    https://www.valuemarketresearch.com/privacy-policyhttps://www.valuemarketresearch.com/privacy-policy

    Time period covered
    2025 - 2033
    Area covered
    Global
    Description

    Global Oxytocin Market is anticipated to experience remarkable expansion, with a projected Compound Annual Growth Rate (CAGR) of 8.72% from 2025 to 2033. According to the market analysis, the market size is forecasted to reach USD 176.11 Million by the end of 2033, up from USD 82.98 Million in 2024.

    The Global Oxytocin market size to cross USD 176.11 Million in 2033. [https://edison.valuemarketre

  20. N

    Data from: Human endogenous oxytocin and its neural correlates show adaptive...

    • neurovault.org
    zip
    Updated Mar 23, 2023
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    (2023). Human endogenous oxytocin and its neural correlates show adaptive responses to social touch based on recent social context [Dataset]. http://identifiers.org/neurovault.collection:13740
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    zipAvailable download formats
    Dataset updated
    Mar 23, 2023
    License

    CC0 1.0 Universal Public Domain Dedicationhttps://creativecommons.org/publicdomain/zero/1.0/
    License information was derived automatically

    Description

    A collection of 56 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

    Collection description

    This collection includes unthresholded maps for all the analyses conducted in the study. Only the conjunction maps are presented thresholded at voxel level p=0.002.

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Silvana Valtcheva; Habon A. Issa; Chloe J. Bair-Marshall; Kathleen A. Martin; Kanghoon Jung; Yiyao Zhang; Hyung-Bae Kwon; Robert C. Froemke (2025). Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries [Dataset]. http://doi.org/10.5281/zenodo.8060338

Neural Circuitry for Maternal Oxytocin Release Induced by Infant Cries

Related Article
Explore at:
Dataset updated
Jun 16, 2025
Dataset provided by
NYU Health Sciences Library
Authors
Silvana Valtcheva; Habon A. Issa; Chloe J. Bair-Marshall; Kathleen A. Martin; Kanghoon Jung; Yiyao Zhang; Hyung-Bae Kwon; Robert C. Froemke
Description

Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This study describes a neural circuit routing auditory information about infant vocalizations to mouse oxytocin neurons. They performed in vivo electrophysiological recordings and photometry from identified oxytocin neurons in awake maternal mice presented with pup calls. For this study, they made cell-attached and whole-cell recordings from PVN oxytocin neurons and other optically-unresponsive PVN neurons in awake head-fixed mouse dams. The dataset contains electrophysiology, behavioral, histology, and fiber photometry data. This study reveals a circuit that unlocks central oxytocin release and maternal behavior in response to pup calls.

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