The dataset contains modeling data spanning from measurements in the NF, with raw software outputs included in the metadata. It provides aerosol characteristics for respiratory tract deposition, such as functional residual capacity and upper respiratory tract volume, where initial deposition occurs. The dataset details particle density, aerodynamic diameter, and particle concentration, all of which influence exposure levels and particle deposition in the respiratory tract during breathing. The dataset has mass deposition rates and deposition fractions across different respiratory regions, and overall deposition fractions, normalized by surface area

The dataset provides toxicity testing in intestinal cell models and includes exposure conditions, and cellular responses such as cell viability (WST-1), ROS quantification (DHR123), and genotoxicity (53BP1).

The dataset focuses on hydrodynamics and surface charge properties. It includes the initial stock concentration (weight-based) and the diluted working concentration. Hydrodynamic diameter and PDI are measured using DLS in suspension, with SDs reported. Surface charge properties are assessed through ζ-potential measurements in water, recorded alongside SDs and pH values, using ELS. The isoelectric point is reported, indicating the pH at which NMs exhibit zero net surface charge. This dataset is complete, with no missing values.

The σ_Acellular.xlsx dataset captures experimental conditions for assessing NM-induced oxidative stress. The reactive molecule (e.g., glutathione (GSH), reactive nitrogen/oxygen species (RNO)) and media type define the reaction environment. The physicochemical properties include hydrodynamic diameter (DLS) and ζ-potential (ELS), with pH recorded. The properties reported in this dataset are not duplicates of those provided in the dedicated physicochemical files. Instead, they represent separate measurements conducted by a different partner, under different conditions, and often in exposure-relevant media. As a result, they should be interpreted as complementary and not redundant. Exposure conditions cover concentration, duration, and intermediate preparation volumes. The dataset records control absorbance, peak absorbance wavelength, and unreacted model molecule concentration. The percentage of the model molecule and GSH/RNO consumed provides a measure of NM-induced redox activity.

The dataset captures exposure conditions and cellular responses, of NM-induced cytotoxicity (WST-1), ROS quantification (DHR123, CellROX) and genotoxicity (53BP1, micronucleus chromosomal damage in binucleated cells using High-Content Analysis). It includes NM solution treatment (e.g., sonication), culture medium (e.g., DMEM), exposure concentration, and duration (h)