Globally, over many years, one of the top drugs for the treatment of HIV/AIDS is Genvoya, marketed by Gilead. In 2023, Genvoya generated some two billion U.S. dollars in revenue. Biktarvy, also marketed by Gilead, was the best-selling HIV/AIDS treatment and generated around 11.9 billion U.S. dollars in revenue. Gilead is the drug manufacturer most specialized in developing drugs for the treatment of HIV/AIDS.
HIV/AIDS cases worldwide
HIV is a virus that attacks the immune system, leading to an increased risk of infections and can lead to death. HIV/AIDS first appeared in global populations in the 1980s. According to current estimates, the prevalence of HIV is highest in low and middle income countries. Eswatini, followed by Lesotho, had the highest rates of HIV infections in 2022. The number of new HIV infections by world region is highest among residents of Eastern and Southern Africa.
Access to HIV/AIDS treatment
Effective treatment for HIV was not available until the early 1990s. Access to therapy has increased since the early 2000s, and as of 2022 there were approximately 30 million people that had access to antiretroviral therapy. Among countries around the world, Uganda, India and Kenya, to name a few, have the lowest rates of access to antiretroviral medications for the treatment of HIV/AIDS. Meanwhile, trends indicate that children living with HIV in Asia or the Pacific have some of the highest rates of access to antiretroviral therapy globally.
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The Prophylactic HIV Drugs Market will expand to reach USD 54.7 billion during 2035 from USD 35.2 billion in 2025 due to an anticipated 4.5% CAGR throughout the forecast period.
Metric | Value |
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Market Size (2025E) | USD 35.2 Billion |
Market Value (2035F) | USD 54.7 Billion |
CAGR (2025 to 2035) | 4.5% |
Country-wise Insights
Country | CAGR (2025 to 2035) |
---|---|
United States | 4.7% |
Country | CAGR (2025 to 2035) |
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United Kingdom | 4.2% |
Country | CAGR (2025 to 2035) |
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European Union | 4.5% |
Country | CAGR (2025 to 2035) |
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Japan | 4.3% |
Country | CAGR (2025 to 2035) |
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South Korea | 4.4% |
Prophylactic HIV Drugs- Segmentation Outlook
Drug Class | Market Share |
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Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTI) | 63.5% |
Distribution Channel | Market Share |
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Hospital Pharmacies | 45.8% |
Competitive Outlook
Company Name | Estimated Market Share (%) |
---|---|
Gilead Sciences | 35-40% |
ViiV Healthcare | 25-30% |
Merck & Co., Inc. | 15-20% |
Johnson & Johnson | 5-10% |
Other Companies (combined) | 10-15% |
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HIV Drugs Market Overview
Attribute | Detail |
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Market Drivers |
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Regional Analysis
Attribute | Detail |
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Leading Region | North America |
Global HIV Drugs Market Snapshot
Attribute | Detail |
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Market Size in 2023 | US$ 28.6 Bn |
Market Forecast (Value) in 2034 | US$ 47.5 Bn |
Growth Rate (CAGR) | 4.7% |
Forecast Period | 2024-2034 |
Historical Data Available for | 2020-2022 |
Quantitative Units | US$ Bn for Value |
Market Analysis | It includes segment analysis as well as regional level analysis. Moreover, qualitative analysis includes drivers, restraints, opportunities, key trends, Porter’s Five Forces analysis, value chain analysis, and key trend analysis. |
Competition Landscape |
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Format | Electronic (PDF) + Excel |
Market Segmentation |
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Regions Covered |
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Countries Covered |
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Companies Profiled |
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Customization Scope | Available Upon Request |
Pricing | Available Upon Request |
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According to Cognitive Market Research, the global HIV drugs market size will be USD 35425.2 million in 2024. It will expand at a compound annual growth rate (CAGR) of 6.80% from 2024 to 2031.
North America held the major market share for more than 40% of the global revenue with a market size of USD 14170.08 million in 2024 and will grow at a compound annual growth rate (CAGR) of 5.0% from 2024 to 2031.
Europe accounted for a market share of over 30% of the global revenue with a market size of USD 10627.56 million.
Asia Pacific held a market share of around 23% of the global revenue with a market size of USD 8147.80 million in 2024 and will grow at a compound annual growth rate (CAGR) of 8.8% from 2024 to 2031.
Latin America had a market share of more than 5% of the global revenue with a market size of USD 1771.26 million in 2024 and will grow at a compound annual growth rate (CAGR) of 6.2% from 2024 to 2031.
Middle East and Africa had a market share of around 2% of the global revenue and was estimated at a market size of USD 708.50 million in 2024 and will grow at a compound annual growth rate (CAGR) of 6.5% from 2024 to 2031.
The multi-class combination drugs held the highest HIV drugs market revenue share in 2024.
Market Dynamics of HIV drugs Market
Key Drivers for HIV drugs Market
Rising number of HIV-positive individuals to Increase the Demand Globally
The HIV drugs market has experienced growth due to rising number of HIV-positive individuals. As global HIV prevalence increases due to factors like higher transmission rates and improved diagnostic capabilities, demand for effective antiretroviral therapies (ART) surges. This growing patient base necessitates the continuous development and supply of innovative drugs to manage HIV effectively, reduce viral loads, and improve quality of life. Increased awareness and testing also contribute to higher diagnosed cases, further expanding the market for HIV treatments and driving pharmaceutical companies to invest in research and development.
Innovations in HIV diagnostic tools to Propel Market Growth
The HIV drugs market has witnessed steady growth, driven by innovations in HIV diagnostic tools. Advances include rapid, point-of-care tests that deliver results within minutes, improving patient access and reducing diagnostic delays. Integrated technologies, such as multiplex assays, detect multiple markers simultaneously, increasing diagnostic accuracy. Additionally, digital platforms for data management streamline monitoring and personalized treatment plans. These innovations not only improve patient outcomes but also stimulate demand for more effective HIV treatments and management solutions, fostering market growth.
Restraint Factor for the HIV drugs Market
High cost of HIV treatment to Limit the Sales
The high costs of HIV medications constrain the growth of HIV drugs market. It involves expensive medications that can be unaffordable for many patients, especially in low-income regions. The costs are compounded by the need for lifelong treatment, regular monitoring, and potential side effects management, which further burdens healthcare systems and patients. This financial barrier limits access to effective treatment, leading to disparities in care and hindering efforts to control the HIV epidemic globally.
Impact of Covid-19 on the HIV drugs Market
The Covid-19 significantly impacted the market by disrupting supply chains, leading to delays in drug production and distribution, increasing lockdowns and restrictions. Additionally, the focus on COVID-19 diverted resources away from HIV programs, affecting drug availability and patient adherence. However, the pandemic also accelerated the adoption of telemedicine and digital health solutions, which helped maintain patient care continuity. Overall, the pandemic highlighted the need for resilient healthcare systems in managing chronic diseases. Introduction of the HIV drugs Market
HIV drugs are medications used to treat Human Immunodeficiency Virus (HIV) infection. They work by suppressing the virus, preventing its replication, and protecting the immune system. These drugs are typically used in combination as antiretroviral therapy (ART) to reduce viral load, improve patient outcomes, and prevent the progression to AIDS. The rising number of HIV-positive individuals, advancemnets in drug development, increasing government initiatives and funding, increased aw...
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The Prophylactic HIV Drugs Market Report is Segmented by Drug (Tenofovir, Emtricitabine, and Other Drugs), Dosage Form (Oral and Topical), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The Report Offers Market Sizes and Forecasts in Terms of Value (USD) for the Above Segments.
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The HIV Drugs Market is segmented based on type and end-user. By type, the market is segmented into nucleoside, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors, fusion inhibitors, and CCR5 antagonists. By end-user, the market is segmented into hospitals & clinics and specialty centers. Recent developments include: July 2021:To make darunavir paired with ritonavir (DRV/r) as a second-line medication for HIV patients living in low and medium-income countries, Unitaid and Clinton Health Access Initiative, Inc. (CHAI) announced a pricing agreement with pharmaceutical company Hetero Labs LTD. The price of the deal is US$ 210 per patient/year., March 2021:An agreement for collaboration to co-develop and co-commercialize long-acting HIV medication was made public by Gilead Sciences Inc. and Merck. To create a two-drug HIV treatment regimen, the firms want to combine lenacapavir, an experimental capsid inhibitor from Gilead, with islatravir, an investigational nucleoside reverse transcriptase translocation inhibitor from Merck.. Notable trends are: Growing prevalence of HIV/AIDS is driving the market growth.
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The Hiv/Aids Drugs Market size was valued at USD 28.79 USD Billion in 2023 and is projected to reach USD 110.60 USD Billion by 2032, exhibiting a CAGR of 21.2 % during the forecast period. HIV/AIDS drugs, known as antiretroviral therapies (ART), are critical in managing and controlling the virus in infected individuals. ART is the use of drugs in combination, which targets the HIV replication in various stages to make its load undetectable and halt its progression to AIDS. HIV medications can be divided into several classes which include NRTIs, NNRTIs, PIs, INSTIs as well as entry inhibitors. Newer trends being adopted in the treatment of HIV disease have been characterized by the combination of two or more drugs in one tablet for compliance and administration of treatment regimens. There are other options of treatment that are newer and that include long-acting injectables and basic combination of two drugs. The existence of HIV/AIDS has impacted the overall health status of the world by increasing the number of people with access to HIV/AIDS drugs and thus reducing the mortality rate among many people. However, there are some challenges that have been associated with their access globally especially in the LICs include, problems of accessibility, issues of drug resistance, and side effects. Key drivers for this market are: Increasing Public Awareness for Safer Medicines to Stimulate Market Value. Potential restraints include: Lack of Access to Treatment and Unawareness of HIV Infection Status May Hinder Growth. Notable trends are: Manufacturers focusing on the Development of Mitral Valve Product will drive the Market .
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The global HIV medicines market is a substantial and rapidly evolving sector, projected to experience significant growth over the forecast period (2025-2033). While precise market size figures for 2019-2024 are unavailable, extrapolating from the available data and considering the typical growth trajectory of pharmaceutical markets, we can assume a substantial market size in 2025, exceeding $20 billion. This considerable value reflects the ongoing need for effective HIV treatment and prevention strategies globally. Market drivers include increasing prevalence of HIV infections, particularly in developing countries, alongside advancements in medication, leading to improved treatment outcomes and increased patient lifespan. The introduction of new, more effective medications, including combinations simplifying administration and improving patient compliance, is fueling market expansion. However, restraints such as high treatment costs, particularly in low- and middle-income countries, coupled with the emergence of drug resistance, present significant challenges. Market segmentation by application (male/female) and type of medication (pill counts) highlights the diverse needs within the patient population and the evolving nature of treatment regimens. The competitive landscape is robust, featuring major players such as Gilead Sciences, Biocon Limited, and others, continuously innovating and competing to meet the demands of this critical market. The market’s regional distribution reflects global disparities in HIV prevalence and healthcare infrastructure. North America and Europe are expected to maintain significant market shares due to established healthcare systems and higher per capita spending on healthcare. However, substantial growth potential exists in regions like Asia Pacific and Africa, driven by increasing awareness, improving access to healthcare, and targeted public health initiatives. Analyzing the individual country performance within each region is crucial for effective market strategy development. Future growth will likely be shaped by the success of new drug development, broader access to affordable treatments, and the ongoing efforts to prevent new infections. The industry will also need to address the challenge of drug resistance and improving patient adherence to treatment regimens. A robust understanding of these trends is vital for stakeholders to effectively navigate this dynamic market.
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Global HIV Drugs market size is expected to reach $42.34 billion by 2029 at 3.8%, segmented as by type, nucleoside reverse transcriptase inhibitors (nrt’s), non- nucleoside reverse transcriptase inhibitors (nnrt’s), protease inhibitors
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The Africa HIV Drugs Market is projected to expand steadily at a rate of approximately 8.20% CAGR from 2024 to 2030. By Drug Class, By Distribution Channel
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The HIV drug market size attained a value of USD 33.54 Billion in 2024. The market is anticipated to grow at a CAGR of 4.50% during the forecast period of 2025-2034 to attain a value of USD 52.09 Billion by 2034.
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The North America HIV drugs market size was valued at USD 23.84 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 36.91 Billion by 2033, exhibiting a CAGR of 4.78% from 2025-2033. The market is fueled by rising HIV prevalence, advancements in antiretroviral therapies, and the demand for innovative treatments, particularly focusing on multi-class combinations, drug resistance, and personalized medicine.
Report Attribute
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Key Statistics
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Base Year
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2024
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Forecast Years
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2025-2033
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Historical Years
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2019-2024
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Market Size in 2024
| USD 23.84 Billion |
Market Forecast in 2033
| USD 36.91 Billion |
Market Growth Rate (2025-2033) | 4.78% |
IMARC Group provides an analysis of the key trends in each segment of the North America HIV drugs market, along with forecasts at the country and regional levels from 2025-2033. The market has been categorized based on drug class and distribution channel.
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The United States HIV drugs market is estimated to expand at a CAGR of 4.30% in the forecast period of 2025-2034.
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The global HIV drugs market size is forecasted to grow with a CAGR of 5.7% between 2024 and 2031, reaching a valuation of USD 52,504.67 million by 2031 from USD 33,807.33 million in 2023.
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The size of the Prophylactic HIV Drugs Market was valued at USD XX Million in 2023 and is projected to reach USD XXX Million by 2032, with an expected CAGR of 4.10% during the forecast period. Prophylactic HIV drugs market is growing steadily with rising awareness about the necessity of preventive treatments. Most of these drugs represent pre-exposure prophylaxis (PrEP) drugs, which are designed to prevent HIV infection before it can take place in high-risk individuals. This market will be driven by increasing HIV rates in Africa, Asia, and some parts of the Americas, besides global efforts toward HIV prevention.The primary drugs that have been successful in the market are Truvada and Descovy, which have shown success in significantly lowering the transmission risk of HIV. Governmental efforts alongside awareness programs that motivate people to use PrEP have contributed much to the growth of the market mainly in well-developed countries with robust healthcare infrastructure. However, access in low-income regions and the cost of drugs, along with the stigma of HIV, continue to be huge challenges. The presence of generics and research on less expensive and longer-acting preventive treatments will help drive growth going forward.In a conclusive trend, the prophylactic HIV drugs market is expected grow with an expanding spread of knowledge and improved access, placing preventive treatment as one of the strategic approaches to global HIV management. Recent developments include: December 2022: The United State Food and Drug Administration (US FDA) approved Sunlenca (lenacapavir), a new type of antiretroviral medication for adult patients living with human immunodeficiency virus type 1 (HIV-1), whose HIV infections cannot be successfully treated with other available treatments due to resistance, intolerance, or safety considerations., In February 2022: The United State Food and Drug Administration (US FDA) approved rilpivirine and cabotegravir (Cabenuva) for 2-month dosing for adults living with HIV-1 infection.. Key drivers for this market are: High Prevalence of HIV/AIDS, Increasing Government Initiatives; Increasing R&D Activities. Potential restraints include: Lower Penetration in Underdeveloped Markets. Notable trends are: Oral Drug Forms Segment is Expected to Hold a Significant Share Over the Forecast Period.
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The size of the Hiv Drugs market was valued at USD XXX billion in 2024 and is projected to reach USD XXX billion by 2033, with an expected CAGR of 5.02% during the forecast period.HIV drugs are those drugs used in the treatment and management of human immunodeficiency virus (HIV) infection. They act by inhibiting the replication of the virus, thus slowing its progression and preventing the spread of the disease. The HIV drugs market comprises a vast number of antiretroviral drugs, such as nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), integrase strand transfer inhibitors (INSTIs), and entry inhibitors. These are used in combination regimens for maximum effect and also to reduce the risk of drug resistance.
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Explore the growth potential of Market Research Intellect's Anti-HIV Drugs Market Report, valued at USD 38.75 billion in 2024, with a forecasted market size of USD 55.12 billion by 2033, growing at a CAGR of 4.85% from 2026 to 2033.
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Asia Pacific HIV drugs market USD 8147.80 million in 2024 and will grow at a compound annual growth rate (CAGR) of 8.8% from 2024 to 2031. Rising internet penetration is expected to aid the sales to USD 14373.1 million by 2031
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The global Drugs for HIV market size was valued at approximately USD 30.5 billion in 2023 and is projected to reach around USD 42.7 billion by 2032, growing at a CAGR of 3.8% from 2024 to 2032. This market is primarily driven by the increasing prevalence of HIV infections globally, advancements in drug development, and supportive governmental and non-governmental initiatives aimed at combating the HIV epidemic.
One of the significant growth factors for the Drugs for HIV market is the rising awareness about HIV/AIDS and the importance of early diagnosis and treatment. Efforts by global health organizations, such as the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS), to promote awareness and preventive measures have significantly contributed to early diagnosis rates, thus driving the demand for antiretroviral therapy (ART). Moreover, the reduction in stigma associated with HIV/AIDS has encouraged more individuals to seek treatment, further bolstering market growth.
Another crucial factor contributing to the market's expansion is the continuous innovation in HIV drug development. The introduction of novel drug classes, combination therapies, and long-acting injectable formulations has improved the efficacy and convenience of HIV treatment regimens. These innovations not only enhance patient compliance but also reduce the risk of drug resistance, thereby improving treatment outcomes. Furthermore, the ongoing research and development (R&D) efforts to discover new therapeutic targets and the development of vaccines offer promising avenues for future market growth.
The supportive regulatory environment and favorable reimbursement policies in several regions also play a pivotal role in the growth of the Drugs for HIV market. Governments and healthcare systems in developed countries, as well as some developing nations, provide substantial funding and reimbursement for HIV treatment, making it more accessible to patients. Initiatives such as the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to Fight AIDS, Tuberculosis, and Malaria have been instrumental in expanding access to HIV drugs, particularly in low- and middle-income countries.
Regionally, North America and Europe are expected to maintain a significant share of the market due to the high prevalence of HIV, advanced healthcare infrastructure, and robust R&D activities. The Asia Pacific region is anticipated to witness the highest growth rate, driven by increasing HIV cases, rising awareness, and improving healthcare facilities. Africa remains a critical focus area due to the high burden of HIV, with efforts being directed towards improving access to treatment and preventive measures.
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) form the backbone of most HIV treatment regimens. These drugs work by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. The effectiveness of NRTIs, combined with their relatively well-tolerated safety profiles, makes them a cornerstone of antiretroviral therapy (ART). The market for NRTIs is bolstered by the continuous development of newer drugs with improved efficacy and reduced side effects. Drugs such as tenofovir alafenamide and emtricitabine are widely used due to their potent antiviral activity and favorable safety profiles.
The demand for NRTIs is also driven by their inclusion in fixed-dose combination therapies, which simplify treatment regimens and enhance patient adherence. For instance, combination drugs like Truvada and Descovy, which contain NRTIs, are used both for treatment and as pre-exposure prophylaxis (PrEP) to prevent HIV infection. The market growth is further supported by ongoing research to develop next-generation NRTIs that can overcome resistance issues and provide better treatment outcomes.
Despite their widespread use, NRTIs face challenges such as the development of drug resistance and potential long-term side effects, including renal toxicity and bone density loss. To address these concerns, pharmaceutical companies are investing in the development of novel NRTIs with improved safety profiles. Additionally, the use of pharmacogenomics to tailor NRTI therapy based on individual genetic profiles is an emerging trend that holds promise for personalized medicine in HIV treatment.
In terms of market dy
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The prophylactic HIV drugs market, valued at approximately $XX million in 2025, is projected to experience steady growth, driven by increasing HIV prevalence, particularly in developing nations, coupled with expanding awareness regarding pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP). The market's 4.10% CAGR from 2019-2033 indicates a consistent demand for these life-saving medications. Key growth drivers include government initiatives promoting wider access to PrEP and PEP, increased research and development efforts focusing on novel drug formulations (e.g., long-acting injectables), and a growing understanding of the importance of preventing HIV transmission. The market segmentation by drug (Tenofovir, Emtricitabine, and other drugs) and dosage form (oral and topical) reflects diverse treatment approaches tailored to individual needs and preferences. While the market faces challenges such as drug resistance and the high cost of treatment, especially in low-income countries, ongoing advancements in drug development and increasing affordability are poised to mitigate these restraints in the coming years. The competition among established pharmaceutical giants like Gilead Sciences, AbbVie, and Johnson & Johnson, alongside the contributions of generic manufacturers, is expected to fuel further market expansion, promoting both innovation and accessibility. Major regional markets include North America (particularly the United States), Europe, and Asia Pacific, reflecting varying levels of HIV prevalence and healthcare infrastructure. The market's robust growth prospects are contingent upon continued investment in public health initiatives, improved access to healthcare in underserved communities, and the ongoing development of safer and more effective prophylactic therapies. This growth will likely be seen across all segments, with oral formulations remaining dominant due to established usage but long-acting injectables capturing a growing market share driven by improved patient compliance. The inclusion of a broader range of drug options in PrEP and PEP regimens will also positively impact market growth. Recent developments include: June 2024: Gilead Sciences Inc. funded two studies on long-acting human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) through the HIV Prevention Trials Network (HPTN). The studies focuses on a long-acting version of lenacapavir administered every six months., March 2024: ViiV Healthcare reported the positive findings from its phase I study of an investigational formulation of cabotegravir, known as cabotegravir ultra long-acting (CAB-ULA), which can be dosed at intervals of at least four months.. Key drivers for this market are: High Prevalence of HIV/AIDS, Increasing Government Initiatives; Increasing R&D Activities. Potential restraints include: High Prevalence of HIV/AIDS, Increasing Government Initiatives; Increasing R&D Activities. Notable trends are: The Oral Drug Forms Segment is Expected to Hold a Significant Share During the Forecast Period.
Globally, over many years, one of the top drugs for the treatment of HIV/AIDS is Genvoya, marketed by Gilead. In 2023, Genvoya generated some two billion U.S. dollars in revenue. Biktarvy, also marketed by Gilead, was the best-selling HIV/AIDS treatment and generated around 11.9 billion U.S. dollars in revenue. Gilead is the drug manufacturer most specialized in developing drugs for the treatment of HIV/AIDS.
HIV/AIDS cases worldwide
HIV is a virus that attacks the immune system, leading to an increased risk of infections and can lead to death. HIV/AIDS first appeared in global populations in the 1980s. According to current estimates, the prevalence of HIV is highest in low and middle income countries. Eswatini, followed by Lesotho, had the highest rates of HIV infections in 2022. The number of new HIV infections by world region is highest among residents of Eastern and Southern Africa.
Access to HIV/AIDS treatment
Effective treatment for HIV was not available until the early 1990s. Access to therapy has increased since the early 2000s, and as of 2022 there were approximately 30 million people that had access to antiretroviral therapy. Among countries around the world, Uganda, India and Kenya, to name a few, have the lowest rates of access to antiretroviral medications for the treatment of HIV/AIDS. Meanwhile, trends indicate that children living with HIV in Asia or the Pacific have some of the highest rates of access to antiretroviral therapy globally.