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ABSTRACT Purpose: To assess the accuracy of prostate-specific antigen (PSA) adjusted for the transition zone volume (PSATZ) in predicting prostate cancer by comparing the ability of several PSA parameters in predicting prostate cancer in men with intermediate PSA levels of 2.6 – 10.0 ng/mL and its ability to reduce unnecessary biopsies. Materials and Methods: This study included 656 patients referred for prostate biopsy who had a serum PSA of 2.6 – 10.0 ng/mL. Total prostate and transition zone volumes were measured by transrectal ultrasound using the prolate ellipsoid method. The clinical values of PSA, free-to-total (F/T) ratio, PSA density (PSAD) and PSATZ for the detection of prostate cancer were calculated and statistical comparisons between biopsy-positive (cancer) and biopsy-negative (benign) were conducted. Results: Cancer was detected in 172 patients (26.2%). Mean PSA, PSATZ, PSAD and F/T ratio were 7.5 ng/mL, 0.68 ng/mL/cc. 0.25 ng/mL/cc and 0.14 in patients with prostate cancer and 6.29 ng/mL, 0.30 ng/mL/cc, 0.16 ng/mL/cc and 0.22 in patients with benign biopsies, respectively. ROC curves analysis demonstrated that PSATZ had a higher area under curve (0,838) than F/T ratio (0.806) (P
The Port Statistical Areas dataset was updated on June 05, 2025 from the United States Army Corp of Engineers (USACE) and is part of the U.S. Department of Transportation (USDOT)/Bureau of Transportation Statistics (BTS) National Transportation Atlas Database (NTAD). USACE works with port authorities from across the United States to develop the statistical port boundaries through an iterative and collaborative process. Port boundary information is prepared by USACE to increase transparency on public waterborne commerce statistic reporting, as well as to modernize how the data type is stored, analyzed, and reported. A Port Statistical Area (PSA) is a region with formally justified shared economic interests and collective reliance on infrastructure related to waterborne movements of commodities that is formally recognized by legislative enactments of state, county, or city governments. PSAs generally contain groups of county legislation for the sole purpose of statistical reporting. Through GIS mapping, legislative boundaries, and stakeholder collaboration, PSAs often serve as the primary unit for aggregating and reporting commerce statistics for broader geographical areas. Per Engineering Regulation 1130-2-520, the U.S. Army Corps of Engineers' Navigation Data Center is responsible to collect, compile, publish, and disseminate waterborne commerce statistics. This task has subsequently been charged to the Waterborne Commerce Statistics Center to perform. Performance of this work is in accordance with the Rivers and Harbors Appropriation Act of 1922. Included in this work is the definition of a port area. A port area is defined in Engineering Pamphlet 1130-2-520 as: (1) Port limits defined by legislative enactments of state, county, or city governments. (2) The corporate limits of a municipality. The USACE enterprise-wide port and port statistical area feature classes per EP 1130-2-520 are organized in SDSFIE 4.0.2 format. A data dictionary, or other source of attribute information, is accessible at https://doi.org/10.21949/2ngc-4984
Data to accompany: Impacts of geographic variability and geologic history on the distribution of post-settlement alluvium (PSA) across the upper Midwest, USA. Alison M. Anders and Bruce L. Rhoads Catena CATENA_108939 Accepted for Publication 11 Mar 2025
A shapefile of the watersheds included in a meta-analysis of post-settlement alluvium in the Central Lowlands/Midwest USA is included as a zipped archive. A data table with PSA thickness, landscape, climate and soils data from the watersheds is provided as a text file. Accelerated floodplain sedimentation related to agricultural development of uplands has produced post-settlement alluvium (PSA) along rivers throughout the upper Midwest, U.S.A. Landscape characteristics in the region vary geographically in relation to differences in geologic history, yet the extent to which this geographic variability influences PSA accumulation remains unexplored. This study uses existing data to assess how non-dimensional PSA thickness varies with landscape characteristics and climate. Geographic variability is associated with three subregions: 1) areas glaciated during the Late Wisconsin Episode (LWE), 2) areas glaciated during Pre-Illinois and Illinois Episodes (PI&IE), and 3) the Paleozoic Plateau (PP), an area where evidence of Quaternary glaciation is highly localized and does not influence geomorphic characteristics of the landscape. These subregions differ significantly in average geomorphic characteristics, including mean watershed slope (WS), mean local relief (LR), fraction of non-contributing area (NCA), pre-settlement drainage density (DD), and mean normalized river steepness (KSN). Non-dimensional PSA thickness also differs significantly among the subregions, increasing systematically with landscape age; it also is significantly positively correlated with LR, KSN and WS, and significantly negatively correlated with NCA. Non-visibly distinct PSA is present in some LWE watersheds characterized by significantly lower KSN and WS relative to other LWE watersheds in which PSA is visibly distinct. These results indicate that PSA thickness and visibility reflect inherited landscape characteristics, emphasizing the importance of geographic setting, geological history, and geomorphic context for understanding historical river sediment dynamics. Spatial variability in PSA thickness also serves as an indicator of river system sensitivity to human-induced land-use change, which informs river management strategies.
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Protein-Protein, Genetic, and Chemical Interactions for PSA (Drosophila melanogaster) curated by BioGRID (https://thebiogrid.org); DEFINITION: Puromycin sensitive aminopeptidase
Predictive Service Areas (PSAs) are geographic areas for which national-level fire weather or fire danger services and products are produced by wildland fire agency meteorologists and intelligence staffs in support of resource allocation and prioritization. A PSA boundary defines areas where 2 or more weather elements or National Fire Danger Rating System (NFDRS) indices exist with a high correlation to historical significant fire size. "Significant fires" are the 95th percentile fire size for the PSA.
1/9/2023 - Spatial and tabular changes made at request of Basil Newmerzhycky (Great Basin), and Gina McGuire (Fire Meterologist). PSA boundaries between Great Basin (GB14) and Northern California (NC08) GACCs aligned to follow GACC boundary in area of East Fork High Rock Canyon Wilderness and Grassy Canyon. Edits by JKuenzi.
8/29/2022 - 8/30/2022 - Spatial and tabular changes made at request of Southern Area GACC (submitted by Dana "Nancy" Ellsworth and Subject Matter Experts). Edits by JKuenzi. Specific changes include:
Puerto Rico changed from 6 PSAs to 1 PSA. PSAName changed to PR for all areas. PSANationalCode changed to "SA52A" for all areas. PSANames and PSANationalCodes = "PR Northwest (number SA52A remains active), PR Southwest (SA52B), PR North (SA53), PR Central (SA54), PR South (SA55), and PR East (SA56)" were all removed.
Florida changed from 10 PSAs to 4 PSAs. PSANames and PSANationalCodes = "FL North Coast (SA44), FL Northeast (SA45A), FL Northeast Coast (SA45B), FL Pan (SA43), FL SE Coast (SA51B), and FL SW Coast (SA51A)" were all removed. Remaining PSAs realigned using linework by AHepworth, and authoritative datasets (Census Counties, and PADUS Modified Jurisdictional Boundaries) to cover all of Florida.
Louisiana changed PSAName from "MS South" to "LA East" where PSANationalCode = "SA22B" .
1/12/2022 - Spatial and tabular changes made while assigning PSAs to islands and merging a handful of small slivers with larger areas Islands identified by Geographic Area Coordination Center (GACC) PSA representatives, Heidi Strader, Julia Rutherford, Dana "Nancy" Ellsworth, and Matt Shameson. Edits by JKuenzi.
1/10/2022 - Spatial and tabular changes made as part of the request to replace all PSAs in the Rocky Mountain Geographic Area Coordination Center (GACC) by Valerie Meyers and Coleen Haskell, both Predictive Services Fire Weather Meteorologists. The total number of PSAs within the Rocky Mountain area went from 74 to 28. Along with new linework, PSAs were re-numbered and named. Topology was used to find and remove gaps and overlaps.Edits by JKuenzi.
10/29/2021 - Spatial changes made. Coastlines matched to other base data layers including: Geographic Area Coordination Centers (GACCs), Dispatch Areas, and Initial Attach Frequency Zones. Process completed with approval from the PSA representatives in each GACC, in order to begin process of vertical integration of PSA data, where appropriate, with other wildland fire base data layers. No interior lines moved except along coast. A few island areas were not specifically labeled with a PSA and have been assigned a PSANationalCode = "None" and "PSAName = "No PSA Assigned". Edits by JKuenzi,
10/25/2021 - Spatial and tabular changes made resulting from proposed change between Southwest and Southern Geographic Area Coordination Centers (GACCs) for use starting 1/10/2022. Seven Predictive Service Areas re-aligned boundaries as described by Charles Maxwell (USFS) Predictive Services Meteorologist, in conjunction with Rich Naden (NPS), Basil Newmerzhycky (BLM), Dana Ellsworth (USFS), and Calvin Miller (USFS). Edits by JKuenzi, USFS. Specific changes made include:
SW13 - split at Texas/New Mexico state line. Area in NM remains SW13. Area in TX/OK becomes SA01.
SW14N - split at Texas/New Mexico state line. Area in NM remains SW14N. Area in TX is split into SA04 and SA09
SW14S - split at Texas/New Mexico state line. Area in NM absorbed by SW14N. Area in TX is split into SA09 and SA08 along county lines.
SW09 - split at Texas/New Mexico state line. Area in NM remains SW09 or is absorbed by SW12. Area in TX is absorbed by SA08.
SW12 - absorbs sliver of SW09 along TX/NM border and the Guadalupe Mtns in TX.
10/20/2021-10/21/2021 - Spatial and tabular changes made while completing topology checks for overlaps and gaps. Over 3400 errors found, but most were because of islands. 1367 errors remain, but are all marked as exceptions. Only major changes, such as complete deletion and re-creation of polygons were noted in the Comments or DateCurrent field. Edits by JKuenzi, USFS.
2/3/2021 - Tabular change made in Alaska to the peninsula where the St. Michael Airport is located. PSA National Code changed from AK14 to AK08 per Nicholas Nauslar, BLM, and Heidi Strader, Fire Weather Program Mgr at Alaska Interagency Coordination Center. Edits by JKuenzi, USFS.
6/20/2020 - PSA dataset attribute table brought into alignment with NWCG Data Standards for Predictive Service Areas. Edits by JKuenzi, USFS.
8/3/2019 - Great Basin updated. Edits by DSampson, BLM.
The 2017 Philippines National Demographic and Health Survey (NDHS 2017) is a nationwide survey with a nationally representative sample of approximately 30,832 housing units. The primary objective of the survey is to provide up-to-date estimates of basic demographic and health indicators. Specifically, the NDHS 2017 collected information on marriage, fertility levels, fertility preferences, awareness and use of family planning methods, breastfeeding, maternal and child health, child mortality, awareness and behavior regarding HIV/AIDS, women’s empowerment, domestic violence, and other health-related issues such as smoking.
The information collected through the NDHS 2017 is intended to assist policymakers and program managers in the Department of Health (DOH) and other organizations in designing and evaluating programs and strategies for improving the health of the country’s population.
National coverage
The survey covered all de jure household members (usual residents) and all women age 15-49 years resident in the sample household.
Sample survey data [ssd]
The sampling scheme provides data representative of the country as a whole, for urban and rural areas separately, and for each of the country’s administrative regions. The sample selection methodology for the NDHS 2017 is based on a two-stage stratified sample design using the Master Sample Frame (MSF), designed and compiled by the PSA. The MSF is constructed based on the results of the 2010 Census of Population and Housing and updated based on the 2015 Census of Population. The first stage involved a systematic selection of 1,250 primary sampling units (PSUs) distributed by province or HUC. A PSU can be a barangay, a portion of a large barangay, or two or more adjacent small barangays.
In the second stage, an equal take of either 20 or 26 sample housing units were selected from each sampled PSU using systematic random sampling. In situations where a housing unit contained one to three households, all households were interviewed. In the rare situation where a housing unit contained more than three households, no more than three households were interviewed. The survey interviewers were instructed to interview only the pre-selected housing units. No replacements and no changes of the preselected housing units were allowed in the implementing stage in order to prevent bias. Survey weights were calculated, added to the data file, and applied so that weighted results are representative estimates of indicators at the regional and national levels.
All women age 15-49 who were either permanent residents of the selected households or visitors who stayed in the households the night before the survey were eligible to be interviewed. Among women eligible for an individual interview, one woman per household was selected for a module on domestic violence.
For further details on sample design, see Appendix A of the final report.
Face-to-face [f2f]
Two questionnaires were used for the NDHS 2017: the Household Questionnaire and the Woman’s Questionnaire. Both questionnaires, based on The DHS Program’s standard Demographic and Health Survey (DHS-7) questionnaires, were adapted to reflect the population and health issues relevant to the Philippines. Input was solicited from various stakeholders representing government agencies, universities, and international agencies.
The processing of the NDHS 2017 data began almost as soon as fieldwork started. As data collection was completed in each PSU, all electronic data files were transferred via an Internet file streaming system (IFSS) to the PSA central office in Quezon City. These data files were registered and checked for inconsistencies, incompleteness, and outliers. The field teams were alerted to any inconsistencies and errors while still in the PSU. Secondary editing involved resolving inconsistencies and the coding of openended questions; the former was carried out in the central office by a senior data processor, while the latter was taken on by regional coordinators and central office staff during a 5-day workshop following the completion of the fieldwork. Data editing was carried out using the CSPro software package. The concurrent processing of the data offered a distinct advantage, because it maximized the likelihood of the data being error-free and accurate. Timely generation of field check tables allowed for more effective monitoring. The secondary editing of the data was completed by November 2017. The final cleaning of the data set was carried out by data processing specialists from The DHS Program by the end of December 2017.
A total of 31,791 households were selected for the sample, of which 27,855 were occupied. Of the occupied households, 27,496 were successfully interviewed, yielding a response rate of 99%. In the interviewed households, 25,690 women age 15-49 were identified for individual interviews; interviews were completed with 25,074 women, yielding a response rate of 98%.
The household response rate is slightly lower in urban areas than in rural areas (98% and 99%, respectively); however, there is no difference by urban-rural residence in response rates among women (98% for each).
The estimates from a sample survey are affected by two types of errors: nonsampling errors and sampling errors. Nonsampling errors are the results of mistakes made in implementing data collection and data processing, such as failure to locate and interview the correct household, misunderstanding of the questions on the part of either the interviewer or the respondent, and data entry errors. Although numerous efforts were made during the implementation of the Philippines National Demographic and Health Survey (NDHS) 2017 to minimize this type of error, nonsampling errors are impossible to avoid and difficult to evaluate statistically.
Sampling errors, on the other hand, can be evaluated statistically. The sample of respondents selected in the NDHS 2017 is only one of many samples that could have been selected from the same population, using the same design and expected size. Each of these samples would yield results that differ somewhat from the results of the actual sample selected. Sampling errors are a measure of the variability among all possible samples. Although the degree of variability is not known exactly, it can be estimated from the survey results.
Sampling error is usually measured in terms of the standard error for a particular statistic (mean, percentage, etc.), which is the square root of the variance. The standard error can be used to calculate confidence intervals within which the true value for the population can reasonably be assumed to fall. For example, for any given statistic calculated from a sample survey, the value of that statistic will fall within a range of plus or minus two times the standard error of that statistic in 95% of all possible samples of identical size and design.
If the sample of respondents had been selected as a simple random sample, it would have been possible to use straightforward formulas for calculating sampling errors. However, the NDHS 2017 sample is the result of a multi-stage stratified design, and, consequently, it was necessary to use more complex formulas. Sampling errors are computed in SAS, using programs developed by ICF. These programs use the Taylor linearization method to estimate variances for survey estimates that are means, proportions, or ratios. The Jackknife repeated replication method is used for variance estimation of more complex statistics such as fertility and mortality rates.
A more detailed description of estimates of sampling errors are presented in Appendix B of the survey final report.
Data Quality Tables - Household age distribution - Age distribution of eligible and interviewed women - Completeness of reporting - Births by calendar years - Reporting of age at death in days - Reporting of age at death in months
See details of the data quality tables in Appendix C of the survey final report.
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PurposeCurrent research has not extensively explored the correlation between Systemic Inflammatory Index (SII) and prostate-specific antibody (PSA) levels. This study aimed to investigate the relationship between the SII and PSA levels in American males aged > 40 years without prostate cancer.MethodsData were obtained from the 2003–2010 National Health and Nutrition Examination Survey (NHANES). Patients without complete SII or PSA data were excluded. Multiple linear regression models were used to investigate the possibility of a linear association between the SII and PSA levels. Fitted smoothed curves and threshold effect analyses were used to characterize the nonlinear relationships.ResultsThe study included 5982 male participants over the age of 40 years from the United States. The average SII (mean ± standard deviation) was 562.78 ± 355.60. The mean value of PSA was 1.85 ± 3.24. The results showed that SII exhibited a positive correlation with PSA (β = 0.0005, 95% CI: (0.0002, 0.0007)), and an interaction test indicated that the effects of age, body mass index, hypertension, and diabetes were not significant for this positive correlation between SII and PSA (all P > 0.05). We discovered an inverted U-shaped connection between the SII and PSA with a turning point (K) of 1168.18 by using a two-segment linear regression model. To the left of the turning point, there was a positive connection between SII and PSA (β = 0.0009,95% CI: (0.0006, 0.0012); P < 0.0001).ConclusionIn the population of men over 40 years old without prostate cancer, SII and PSA exhibited a non-linear relationship. Specifically, there was a positive correlation between SII and PSA levels when the SII value was < 1168.18.
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Threshold effects analysis of PSA using a two-segment linear regression mode.
The 2022 Philippines National Demographic and Health Survey (NDHS) was implemented by the Philippine Statistics Authority (PSA). Data collection took place from May 2 to June 22, 2022.
The primary objective of the 2022 NDHS is to provide up-to-date estimates of basic demographic and health indicators. Specifically, the NDHS collected information on fertility, fertility preferences, family planning practices, childhood mortality, maternal and child health, nutrition, knowledge and attitudes regarding HIV/AIDS, violence against women, child discipline, early childhood development, and other health issues.
The information collected through the NDHS is intended to assist policymakers and program managers in designing and evaluating programs and strategies for improving the health of the country’s population. The 2022 NDHS also provides indicators anchored to the attainment of the Sustainable Development Goals (SDGs) and the new Philippine Development Plan for 2023 to 2028.
National coverage
The survey covered all de jure household members (usual residents), all women aged 15-49, and all children aged 0-4 resident in the household.
Sample survey data [ssd]
The sampling scheme provides data representative of the country as a whole, for urban and rural areas separately, and for each of the country’s administrative regions. The sample selection methodology for the 2022 NDHS was based on a two-stage stratified sample design using the Master Sample Frame (MSF) designed and compiled by the PSA. The MSF was constructed based on the listing of households from the 2010 Census of Population and Housing and updated based on the listing of households from the 2015 Census of Population. The first stage involved a systematic selection of 1,247 primary sampling units (PSUs) distributed by province or HUC. A PSU can be a barangay, a portion of a large barangay, or two or more adjacent small barangays.
In the second stage, an equal take of either 22 or 29 sample housing units were selected from each sampled PSU using systematic random sampling. In situations where a housing unit contained one to three households, all households were interviewed. In the rare situation where a housing unit contained more than three households, no more than three households were interviewed. The survey interviewers were instructed to interview only the preselected housing units. No replacements and no changes of the preselected housing units were allowed in the implementing stage in order to prevent bias. Survey weights were calculated, added to the data file, and applied so that weighted results are representative estimates of indicators at the regional and national levels.
All women age 15–49 who were either usual residents of the selected households or visitors who stayed in the households the night before the survey were eligible to be interviewed. Among women eligible for an individual interview, one woman per household was selected for a module on women’s safety.
For further details on sample design, see APPENDIX A of the final report.
Computer Assisted Personal Interview [capi]
Two questionnaires were used for the 2022 NDHS: the Household Questionnaire and the Woman’s Questionnaire. The questionnaires, based on The DHS Program’s model questionnaires, were adapted to reflect the population and health issues relevant to the Philippines. Input was solicited from various stakeholders representing government agencies, academe, and international agencies. The survey protocol was reviewed by the ICF Institutional Review Board.
After all questionnaires were finalized in English, they were translated into six major languages: Tagalog, Cebuano, Ilocano, Bikol, Hiligaynon, and Waray. The Household and Woman’s Questionnaires were programmed into tablet computers to allow for computer-assisted personal interviewing (CAPI) for data collection purposes, with the capability to choose any of the languages for each questionnaire.
Processing the 2022 NDHS data began almost as soon as fieldwork started, and data security procedures were in place in accordance with confidentiality of information as provided by Philippine laws. As data collection was completed in each PSU or cluster, all electronic data files were transferred securely via SyncCloud to a server maintained by the PSA Central Office in Quezon City. These data files were registered and checked for inconsistencies, incompleteness, and outliers. The field teams were alerted to any inconsistencies and errors while still in the area of assignment. Timely generation of field check tables allowed for effective monitoring of fieldwork, including tracking questionnaire completion rates. Only the field teams, project managers, and NDHS supervisors in the provincial, regional, and central offices were given access to the CAPI system and the SyncCloud server.
A team of secondary editors in the PSA Central Office carried out secondary editing, which involved resolving inconsistencies and recoding “other” responses; the former was conducted during data collection, and the latter was conducted following the completion of the fieldwork. Data editing was performed using the CSPro software package. The secondary editing of the data was completed in August 2022. The final cleaning of the data set was carried out by data processing specialists from The DHS Program in September 2022.
A total of 35,470 households were selected for the 2022 NDHS sample, of which 30,621 were found to be occupied. Of the occupied households, 30,372 were successfully interviewed, yielding a response rate of 99%. In the interviewed households, 28,379 women age 15–49 were identified as eligible for individual interviews. Interviews were completed with 27,821 women, yielding a response rate of 98%.
The estimates from a sample survey are affected by two types of errors: (1) nonsampling errors and (2) sampling errors. Nonsampling errors are the results of mistakes made in implementing data collection and in data processing, such as failure to locate and interview the correct household, misunderstanding of the questions on the part of either the interviewer or the respondent, and data entry errors. Although numerous efforts were made during the implementation of the 2022 Philippines National Demographic and Health Survey (2022 NDHS) to minimize this type of error, nonsampling errors are impossible to avoid and difficult to evaluate statistically.
Sampling errors, on the other hand, can be evaluated statistically. The sample of respondents selected in the 2022 NDHS is only one of many samples that could have been selected from the same population, using the same design and identical size. Each of these samples would yield results that differ somewhat from the results of the actual sample selected. Sampling errors are a measure of the variability between all possible samples. Although the degree of variability is not known exactly, it can be estimated from the survey results.
A sampling error is usually measured in terms of the standard error for a particular statistic (mean, percentage, etc.), which is the square root of the variance. The standard error can be used to calculate confidence intervals within which the true value for the population can reasonably be assumed to fall. For example, for any given statistic calculated from a sample survey, the value of that statistic will fall within a range of plus or minus two times the standard error of that statistic in 95% of all possible samples of identical size and design.
If the sample of respondents had been selected as a simple random sample, it would have been possible to use straightforward formulas for calculating sampling errors. However, the 2022 NDHS sample was the result of a multistage stratified design, and, consequently, it was necessary to use more complex formulas. Sampling errors are computed in SAS using programs developed by ICF. These programs use the Taylor linearization method to estimate variances for survey estimates that are means, proportions, or ratios. The Jackknife repeated replication method is used for variance estimation of more complex statistics such as fertility and mortality rates.
A more detailed description of estimates of sampling errors are presented in APPENDIX B of the survey report.
Data Quality Tables
See details of the data quality tables in Appendix C of the final report.
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License information was derived automatically
Protein-Protein, Genetic, and Chemical Interactions for PSA-3 (Caenorhabditis elegans) curated by BioGRID (https://thebiogrid.org); DEFINITION: Protein PSA-3
This record contains raw data related to article "Connecting the use of innovative treatments and glucocorticoids with the multidisciplinary evaluation through rule-based natural-language processing: a real-world study on patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis" Abstract Background: The impact of a multidisciplinary management of rheumatoid arthritis (RA), psoriatic arthritis (PsA), and psoriasis on systemic glucocorticoids or innovative treatments remains unknown. Rule-based natural language processing and text extraction help to manage large datasets of unstructured information and provide insights into the profile of treatment choices. Methods: We obtained structured information from text data of outpatient visits between 2017 and 2022 using regular expressions (RegEx) to define elastic search patterns and to consider only affirmative citation of diseases or prescribed therapy by detecting negations. Care processes were described by binary flags which express the presence of RA, PsA and psoriasis and the prescription of glucocorticoids and biologics or small molecules in each cases. Logistic regression analyses were used to train the classifier to predict outcomes using the number of visits and the other specialist visits as the main variables. Results: We identified 1743 patients with RA, 1359 with PsA and 2,287 with psoriasis, accounting for 5,677, 4,468 and 7,770 outpatient visits, respectively. Among these, 25% of RA, 32% of PsA and 25% of psoriasis cases received biologics or small molecules, while 49% of RA, 28% of PsA, and 40% of psoriasis cases received glucocorticoids. Patients evaluated also by other specialists were treated more frequently with glucocorticoids (70% vs. 49% for RA, 60% vs. 28% for PsA, 51% vs. 40% for psoriasis; p < 0.001) as well as with biologics/small molecules (49% vs. 25% for RA, 64% vs. 32% in PsA; 51% vs. 25% for psoriasis; p < 0.001) compared to cases seen only by the main specialist. Conclusion: Patients with RA, PsA, or psoriasis undergoing multiple evaluations are more likely to receive innovative treatments or glucocorticoids, possibly reflecting more complex cases.
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The global market size of Psoriatic Arthritis (PsA) Treatments is $XX million in 2018 with XX CAGR from 2014 to 2018, and it is expected to reach $XX million by the end of 2024 with a CAGR of XX% from 2019 to 2024.
Global Psoriatic Arthritis (PsA) Treatments Market Report 2019 - Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Psoriatic Arthritis (PsA) Treatments industry. The key insights of the report:
1.The report provides key statistics on the market status of the Psoriatic Arthritis (PsA) Treatments manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.
2.The report provides a basic overview of the industry including its definition, applications and manufacturing technology.
3.The report presents the company profile, product specifications, capacity, production value, and 2013-2018 market shares for key vendors.
4.The total market is further divided by company, by country, and by application/type for the competitive landscape analysis.
5.The report estimates 2019-2024 market development trends of Psoriatic Arthritis (PsA) Treatments industry.
6.Analysis of upstream raw materials, downstream demand, and current market dynamics is also carried out
7.The report makes some important proposals for a new project of Psoriatic Arthritis (PsA) Treatments Industry before evaluating its feasibility.
There are 4 key segments covered in this report: competitor segment, product type segment, end use/application segment and geography segment.
For competitor segment, the report includes global key players of Psoriatic Arthritis (PsA) Treatments as well as some small players.
The information for each competitor includes:
* Company Profile
* Main Business Information
* SWOT Analysis
* Sales, Revenue, Price and Gross Margin
* Market Share
For product type segment, this report listed main product type of Psoriatic Arthritis (PsA) Treatments market
* Product Type I
* Product Type II
* Product Type III
For end use/application segment, this report focuses on the status and outlook for key applications. End users sre also listed.
* Application I
* Application II
* Application III
For geography segment, regional supply, application-wise and type-wise demand, major players, price is presented from 2013 to 2023. This report covers following regions:
* North America
* South America
* Asia & Pacific
* Europe
* MEA (Middle East and Africa)
The key countries in each region are taken into consideration as well, such as United States, China, Japan, India, Korea, ASEAN, Germany, France, UK, Italy, Spain, CIS, and Brazil etc.
Reasons to Purchase this Report:
* Analyzing the outlook of the market with the recent trends and SWOT analysis
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* Market value (USD Million) and volume (Units Million) data for each segment and sub-segment
* Competitive landscape involving the market share of major players, along with the new projects and strategies adopted by players in the past five years
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The 2013 Survey on Information and Communication Technology (SICT) is one of the designated statistical activities undertaken by the Philippine Statistics Authority (PSA) to collect and generate information on the availability, distribution and access/utilization of ICT among establishments in the country.
The objectives of the 2013 SICT is to provide key measures of ICT access and use among establishments which will enable the assessment and monitoring of the digital divide in the country. Specifically, the survey aims to measure the following: - component of ICT resources and their utilization by establishments; - diffusion of ICT into establishments from various sources; - e-commerce transactions from data on e-commerce sales/revenue and purchases; - cellular mobile phone business transactions from data on sales/revenue; - estimate of the number of ICT workers in establishments; - methods of disposal of ICT equipment.
The SICT 2013 was a rider survey of the 2013 Annual Survey of Philippine Business and Industry.
Regional - "core" ICT and BPM industries are the regions National - "non-core" ICT industries
An establishment, which is defined as an economic unit under a single ownership or control, i.e., under a single legal entity, engaged in one or predominantly one kind of economic activity at a single fixed location
The 2013 Survey on Information and Communication Technology (SICT) of Philippine Business and Industry covered all industries included in the 2013 Annual Survey of Philippine Business and Industry (ASPBI).
For the purpose of the survey, these industries were classified as core ICT industries and non-core ICT Industries. Core ICT industries were industries comprising the Information Economy (IE). The Information Economy is a term used to describe the economic and social value created through the ability to rapidly exchange information at anytime, anywhere to anyone. A distinctive characteristic of the information economy is the intensive use, by businesses of ICT for the collection, storage, processing and transmission of information. The use of ICT is supported by supply of ICT products from an ICT-producing sector through trade.
Information Economy is composed of the Information and Communication Technology Sector and Content and Media Sector. Industries comprising these two sectors are as follows: 1) Information and Communication Technology - ICT manufacturing industries - ICT trade industries - ICT service industries: - Software publishing - Telecommunication services - Computer programming, consultancy and related services - Data processing, hosting and related activities; web portals - Repair of computers and communication equipment 2) Content and Media - Publishing activities - Motion picture, video and television programme production, sound recording and music publishing activities - Programming and broadcasting activities
Sample survey data [ssd]
The 2013 SICT utilized the stratified systematic sampling design with five-digit PSIC serving as industry strata (industry domain) and the employment size as the second stratification variable.
There were only two strata used for the survey, as follows: TE of 20 and over and TE of less than 20.
The industry stratification for the 2013 SICT is the 5-digit PSIC for both the core ICT industries and for the non-core ICT industries. It has the same industry strata as that of the 2013 ASPBI.
Establishments engaged in the core ICT industries were completely enumerated, regardless of employment size.
The establishments classified in the non-core ICT industries and with total employment of 20 and over were covered on a 20 percent sampling basis for each of the industry domain at the national level. The minimum sample size is set to 3 establishments and maximum of 10 establishments per cell (industry domain).
However, when the total number of establishments in the cell is less than the set minimum sample size, all establishments in that cell were taken as samples.
Mail Questionnaire [mail]
The scope of the study includes: - general information about the establishment - information and communication technology (ICT) resources of the establishment - network channels - use of ICT resources, Internet - website of the establishment - e-commerce via internet - e-commerce via computer networks other than the internet - use of mobile phones in selling and other business operation - purchase and disposal of ICT equipment
Manual processing took place in Provincial Offices at a number of stages throughout the processing, including: - coding of some data items - editing of questionnaires - checking completeness of entries - consistency check among variables.
Data processing was done in Field Offices and Central Office.
Field Offices were responsible for: - online data encoding and updating - completeness and consistency edits - folioing of questionnaires.
Central Office was responsible for: - online validation - completeness and consistency checks - summarization - tabulation.
The overall response rate for the 2013 SICT was 87.04 percent (9,562 of the 10,986 sample establishments). This included receipts of "good" questionnaires, partially accomplished questionnaires, reports of closed, moved out or out of scope establishments. Sample establishments under core ICT industries reported 89.96 percent response rate ( 5,421 out of 6,026 establishments) while non-core ICT industries response rate was 83.48 percent (3,633 out of 4,352 sample establishments). On the other hand, industries classified in Business Process Management (BPM) had a response rate of 83.55 percent (508 out of 608 establishments).
Not computed
Data estimates were checked with those from other related surveys or administrative data.
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Objective: This study compared survival of prostate cancer patients with low prostate specific antigen level (PSA ≤ 10 ng/ml) and high-grades of Gleason score (GS) of 8–10 with different treatment options (i.e., radical prostatectomy [RP], external beam radiotherapy [EBRT], or external beam radiotherapy with brachytherapy [EBRT+BT]).Materials and Methods: The Surveillance, Epidemiology and End Results (SEER) database data (2004–2013), and overall survival (OS) and prostate cancer-specific mortality (PCSM), were evaluated using the Cox proportional hazards regression model and Fine and Gray competing risk model.Results: The SEER data contained 9,114 patients, 4,175 of whom received RP, 4,114 received EBRT, and 825 received EBRT+BT with a median follow-up duration of 47 months. RP patients had significantly better OS than patients with EBRT and EBRT+BT (adjusted HR [AHR]: 3.36, 95% CI: 2.43–4.64, P < 0.001; AHR: 2.15, 95% CI: 1.32–3.48, P = 0.002; respectively). There was no statistical difference in PCSM between RP and EBRT+BT (AHR: 1.31, 95% CI: 0.61–2.80, P = 0.485), while EBRT had worse OS (P < 0.05). The subgroup analysis revealed that there was no statistical difference in prognosis of patients with age of >70 years old, or PSA levels of ≤ 2.5 ng/ml between RP and EBRT+BT (P > 0.05).Conclusion: RP patients with low PSA levels and high GS had better OS compared to either EBRT or EBRT+BT, while RP and EBRT+BT resulted in significantly lower PCSM, compared to EBRT. Moreover, EBRT+BT and RP were associated with similar survival of patients with age of > 70 years old, or PSA levels of ≤ 2.5 ng/ml.
The 2013 NDHS is designed to provide information on fertility, family planning, and health in the country for use by the government in monitoring the progress of its programs on population, family planning and health.
In particular, the 2013 NDHS has the following specific objectives: • Collect data which will allow the estimation of demographic rates, particularly fertility rates and under-five mortality rates by urban-rural residence and region. • Analyze the direct and indirect factors which determine the level and patterns of fertility. • Measure the level of contraceptive knowledge and practice by method, urban-rural residence, and region. • Collect data on health, immunizations, prenatal and postnatal check-ups, assistance at delivery, breastfeeding, and prevalence and treatment of diarrhea, fever and acute respiratory infections among children below five years old. • Collect data on environmental health, utilization of health facilities, health care financing, prevalence of common non-communicable and infectious diseases, and membership in the National Health Insurance Program (PhilHealth). • Collect data on awareness of cancer, heart disease, diabetes, dengue fever and tuberculosis. • Determine the knowledge of women about AIDS, and the extent of misconception on HIV transmission and access to HIV testing. • Determine the extent of violence against women.
National coverage
Sample survey data [ssd]
The sample selection methodology for the 2013 NDHS is based on a stratified two-stage sample design, using the 2010 Census of Population and Housing (CPH) as a frame. The first stage involved a systematic selection of 800 sample enumeration areas (EAs) distributed by stratum (region, urban/rural). In the second stage, 20 sample housing units were selected from each sample EA, using systematic random sampling.
All households in the sampled housing units were interviewed. An EA is defined as an area with discern able boundaries consisting of contiguous households. The sample was designed to provide data representative of the country and its 17 administrative regions.
Further details on the sample design and implementation are given in Appendix A of the final report.
Face-to-face [f2f]
The 2013 NDHS used three questionnaires: Household Questionnaire, Individual Woman’s Questionnaire, and Women’s Safety Module. The development of these questionnaires resulted from the solicited comments and suggestions during the deliberation in the consultative meetings and separate meetings conducted with the various agencies/organizations namely: PSA-NSO, POPCOM, DOH, FNRI, ICF International, NEDA, PCW, PhilHealth, PIDS, PLCPD, UNFPA, USAID, UPPI, UPSE, and WHO. The three questionnaires were translated from English into six major languages - Tagalog, Cebuano, Ilocano, Bicol, Hiligaynon, and Waray.
The main purpose of the Household Questionnaire was to identify female members of the sample household who were eligible for interview with the Individual Woman’s Questionnaire and the Women’s Safety Module.
The Individual Woman’s Questionnaire was used to collect information from all women aged 15-49 years.
The Women’s Safety Module was used to collect information on domestic violence in the country, its prevalence, severity and frequency from only one selected respondent from among all the eligible women who were identified from the Household Questionnaire.
All completed questionnaires and the control forms were returned to the PSA-NSO central office in Manila for data processing, which consisted of manual editing, data entry and verification, and editing of computer-identified errors. An ad-hoc group of thirteen regular employees from the DSSD, the Information Resources Department (IRD), and the Information Technology Operations Division (ITOD) of the NSO was created to work fulltime and oversee data processing operation in the NDHS Data Processing Center that was carried out at the NSO-CVEA Building in Quezon City, Philippines. This group was responsible for the different aspects of NDHS data processing. There were 19 data encoders hired to process the data who underwent training on September 12-13, 2013.
Data entry started on September 16, 2013. The computer package program called Census and Survey Processing System (CSPro) was used for data entry, editing, and verification. Mr. Alexander Izmukhambetov, a data processing specialist from ICF International, spent two weeks at NSO in September 2013 to finalize the data entry program. Data processing was completed on December 6, 2013.
For the 2013 NDHS sample, 16,732 households were selected, of which 14,893 were occupied. Of these households, 14,804 were successfully interviewed, yielding a household response rate of 99.4 percent. The household response rates in urban and rural areas are almost identical.
Among the households interviewed, 16,437 women were identified as eligible respondents, and the interviews were completed for 16,155 women, yielding a response rate of 98.3 percent. On the other hand, for the women’s safety module, from a total of 11,373 eligible women, 10,963 were interviewed with privacy, translating to a 96.4 percent response rate. At the individual level, urban and rural response rates showed no difference. The principal reason for non-response among women was the failure to find individuals at home, despite interviewers’ repeated visits to the household.
The estimates from a sample survey are affected by two types of errors: (1) nonsampling errors and (2) sampling errors. Nonsampling errors are the results of mistakes made in implementing data collection and data processing, such as failure to locate and interview the correct household, misunderstanding of the questions on the part of either the interviewer or the respondent, and data entry errors. Although numerous efforts were made during the implementation of the 2013 National Demographic and Health Survey (NDHS) to minimize this type of error, nonsampling errors are impossible to avoid and difficult to evaluate statistically.
Sampling errors, on the other hand, can be evaluated statistically. The sample of respondents selected in the 2013 NDHS is only one of many samples that could have been selected from the same population, using the same design and identical size. Each of these samples would yield results that differ somewhat from the results of the actual sample selected. Sampling error is a measure of the variability between the results of all possible samples. Although the degree of variability is not known exactly, it can be estimated from the survey data.
A sampling error is usually measured in terms of the standard error for a particular statistic (mean, percentage, etc.), which is the square root of the variance. The standard error can be used to calculate confidence intervals within which the true value for the population can reasonably be assumed to fall. For example, for any given statistic calculated from a sample survey, the value of that statistic will fall within a range of plus or minus two times the standard error of that statistic in 95 percent of all possible samples of identical size and design.
If the sample of respondents had been selected as a simple random sample, it would have been possible to use straightforward formulas for calculating sampling errors. However, the 2013 NDHS sample is the result of a multistage stratified design, and, consequently, it was necessary to use more complex formulae. The computer software used to calculate sampling errors for the 2013 NDHS is a SAS program. This program used the Taylor linearization method for variance estimation for survey estimates that are means or proportions. The Jackknife repeated replications method is used for variance estimation of more complex statistics such as fertility and mortality rates.
The Taylor linearization method treats any percentage or average as a ratio estimate, r = y/x, where y represents the total sample value for variable y, and x represents the total number of weighted cases in the group or subgroup under consideration.
Further details on sampling errors calculation are given in Appendix B of the final report.
Data quality tables were produced to review the quality of the data: - Household age distribution - Age distribution of eligible and interviewed women - Completeness of reporting - Births by calendar years - Reporting of age at death in days - Reporting of age at death in months
Note: The tables are presented in APPENDIX C of the final report.
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ObjectivesThe study aims to evaluate the applicability of the D2T psoriatic arthritis (PsA) definition, adapted from rheumatoid arthritis, within a single-center observational cohort of PsA patients treated with b/tsDMARDs. In addition, we aimed to establish a numerical index defining D2T-PsA based on the ratio of observed to expected failed b/tsDMARDs and to develop a predictive model identifying features associated with the D2T condition.MethodsThe study included 267 consecutive adult PsA patients receiving b/tsDMARDs, collecting demographic, clinical, and clinimetric data. The prevalence of D2T PsA patients was assessed using a proposed definition. We then developed a predictive model to assess treatment difficulty, utilizing PsA-normalized failed b/tsDMARDs. A generalized linear model was applied to identify clinical and demographic features associated with D2T PsA, employing a bagging procedure for robust variable selection, followed by univariate and multivariable analyses.ResultsAmong the 267 patients, only 8 of them (2.9%) met the proposed D2T PsA criteria. In a subset of 177 patients analyzed using the predictive model, 17.2% of them demonstrated higher treatment difficulty. Univariate analysis revealed associations between treatment difficulty and female sex, psoriasis pattern, fibromyalgia, and steroid therapy. Multivariate analysis confirmed significant associations between fibromyalgia, nail and pustular psoriasis, and steroid use.ConclusionAccording to the predictive model, the proposed D2T PsA definition identified a small subset of patients with increased treatment difficulty. These findings highlight the need for refining the criteria to better define D2T PsA patients, providing valuable insights into managing complex treatment challenges in PsA.
The aim of this work was to investigate volatile organic compounds (VOCs) emanating from urine samples to determine whether they can be used to classify samples into those from prostate cancer and non-cancer groups. Participants were men referred for a trans-rectal ultrasound-guided prostate biopsy because of an elevated prostate specific antigen (PSA) level or abnormal findings on digital rectal examination. Urine samples were collected from patients with prostate cancer (n = 59) and cancer-free controls (n = 43), on the day of their biopsy, prior to their procedure. VOCs from the headspace of basified urine samples were extracted using solid-phase micro-extraction and analysed by gas chromatography/mass spectrometry. Classifiers were developed using Random Forest (RF) and Linear Discriminant Analysis (LDA) classification techniques. PSA alone had an accuracy of 62–64% in these samples. A model based on 4 VOCs, 2,6-dimethyl-7-octen-2-ol, pentanal, 3-octanone, and 2-octanone, was marginally more accurate 63–65%. When combined, PSA level and these four VOCs had mean accuracies of 74% and 65%, using RF and LDA, respectively. With repeated double cross-validation, the mean accuracies fell to 71% and 65%, using RF and LDA, respectively. Results from VOC profiling of urine headspace are encouraging and suggest that there are other metabolomic avenues worth exploring which could help improve the stratification of men at risk of prostate cancer. This study also adds to our knowledge on the profile of compounds found in basified urine, from controls and cancer patients, which is useful information for future studies comparing the urine from patients with other disease states.
Background: There is conflicting evidence about the association between prostate cancer and Lower Urinary Tract Symptoms (LUTS). We aimed to describe the prevalence of LUTS and its association with prostate cancer risk. Methods: We studied the association between International Prostate Symptom Score (IPSS) and prostate cancer in a population-based sample of men (n = 45,595) aged 50–69 years from the Stockholm3 study. Men with PSA ≥3 ng/ml (n = 4579) underwent systematic prostate biopsies. We used the International Society of Urological Pathology Gleason Grading (ISUP grade) and performed regression analysis for risk of any cancer (n = 1797), ISUP grade ≥2 (n = 840) and advanced cancer, defined as ISUP grade ≥3 or cT ≥3 (n = 353). Results: 74.6% of all men had no or mild LUTS (IPSS ≤7) and 3.2% had severe LUTS (IPSS >19). Men with any, ISUP grade ≥2 or advanced cancer had lower median IPSS compared to men with benign biopsy (any cancer: 4 (IQR 2–9); ISUP grade ≥2: 4 (2–8); advanced cancer: 4 (2–8); benign biopsy: 6 (3–11); p < 0.05). IPSS was not associated with increased risk of cancer in multivariate analyses (OR (any cancer) 0.97; 95% CI 0.96–0.98; OR (ISUP grade ≥2) 0.97; 95% CI 0.96–0.99; OR (advanced cancer) 0.99; 95% CI 0.99–1.01). Conclusions: Three-quarters of men aged 50–69 years report no or mild LUTS. Our data do not support any clinically meaningful association between LUTS and prostate cancer. Specifically, men with advanced prostate cancer did not exhibit more urinary symptoms than men without cancer.
This includes data from the VMC instrument onboard Mars Express.
Each product consists on a png file and a json file with the same name. All these products are high level products made by projecting an stacking original images, available in the European Space Agency (ESA), Planetary Science Archive (PSA). All the data is in cilindrical projection.
The json files contain metadata related to each product, the metadata is:PRNAME: Product namePR_CORNERS: Coordinates for the top left and bottom right corners.PR_WIDTH: Width of the map of Mars in this projection in pixels (i.e., not the width of the image, as it does not cover the whole range of longitudes).SRC_PRS: List of source products. They are available at ESA PSA.TIME: Mean timestamp for the product.
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ABSTRACT Purpose: To assess the accuracy of prostate-specific antigen (PSA) adjusted for the transition zone volume (PSATZ) in predicting prostate cancer by comparing the ability of several PSA parameters in predicting prostate cancer in men with intermediate PSA levels of 2.6 – 10.0 ng/mL and its ability to reduce unnecessary biopsies. Materials and Methods: This study included 656 patients referred for prostate biopsy who had a serum PSA of 2.6 – 10.0 ng/mL. Total prostate and transition zone volumes were measured by transrectal ultrasound using the prolate ellipsoid method. The clinical values of PSA, free-to-total (F/T) ratio, PSA density (PSAD) and PSATZ for the detection of prostate cancer were calculated and statistical comparisons between biopsy-positive (cancer) and biopsy-negative (benign) were conducted. Results: Cancer was detected in 172 patients (26.2%). Mean PSA, PSATZ, PSAD and F/T ratio were 7.5 ng/mL, 0.68 ng/mL/cc. 0.25 ng/mL/cc and 0.14 in patients with prostate cancer and 6.29 ng/mL, 0.30 ng/mL/cc, 0.16 ng/mL/cc and 0.22 in patients with benign biopsies, respectively. ROC curves analysis demonstrated that PSATZ had a higher area under curve (0,838) than F/T ratio (0.806) (P