In 2023, around 72,776 people in the United States died from a drug overdose that involved fentanyl. This was the second-highest number of fentanyl overdose deaths ever recorded in the United States, and a significant increase from the number of deaths reported in 2019. Fentanyl overdoses are now the driving force behind the opioid epidemic, accounting for the majority of overdose deaths in the United States. What is fentanyl? Fentanyl is an extremely potent synthetic opioid similar to morphine, but more powerful. It is a prescription drug but is also manufactured illegally and is sometimes mixed with other illicit drugs such as heroin and cocaine, often without the user’s knowledge. The potency of fentanyl makes it very addictive and puts users at a high risk for overdose. Illegally manufactured fentanyl has become more prevalent in the United States in recent years, leading to a huge increase in drug overdose deaths. In 2022, the rate of drug overdose death involving fentanyl was 22.7 per 100,000 population, compared to a rate of just one per 100,000 population in the year 2013. Fentanyl overdoses by gender and race/ethnicity As of 2022, the rate of drug overdose deaths involving fentanyl in the United States is over two times higher among men than women. Rates of overdose death involving fentanyl were low for both men and women until around the year 2014 when they began to quickly increase, especially for men. In 2022, there were around 19,880 drug overdose deaths among women that involved fentanyl compared to 53,958 such deaths among men. At that time, the rate of fentanyl overdose deaths was highest among non-Hispanic American Indian or Alaska Natives and lowest among non-Hispanic Asians. However, from the years 2014 to 2018, non-Hispanic whites had the highest fentanyl overdose death rates.

In 2023, around ****** people died from opioid overdoses in the United States. This statistic presents the number of opioid overdose deaths in the U.S. from 1999 to 2023.

It is projected that if the opioid overdose crisis stabilizes by the year 2020 there will be around ******* overdose deaths from prescription and illicit opioids from 2016 to 2025. If the crisis does not stabilize until the year 2025 it is predicted that overdose deaths due to illicit opioids will reach a total of over ****million from 2016 to 2025.

The graph illustrates the number of deaths from fentanyl in the United States from 1999 to 2022. The x-axis represents the years, spanning from '99 to '22, while the y-axis displays the annual number of fentanyl-related fatalities. Over this 24-year period, deaths rise dramatically from 730 in 1999 to a peak of 73,838 in 2022. Notable milestones include an increase to 1,742 deaths in 2005, a significant jump to 9,580 in 2015, and a sharp escalation to 70,601 deaths by 2021. The data reveals a consistent and severe upward trend in fentanyl-related deaths, particularly accelerating in the mid-2010s. This information is presented in a line graph format, effectively highlighting the dramatic increase in fatalities due to fentanyl across the United States over the specified years.

Data was compiled from the CDC Wonder database for each year and combined into a single spreadsheet. Each year has both a death field and a rate of fatalities per 100,000 people. The CDC does not publish the number of fatalities by county if the total is less than 10 in a given year. The CDC does not post a rate of fatalities if the total number of deaths per county is less than 20. The population field contains estimates from 2018 and is NOT the data used to generate the rates over time.The following details are copied directly from the CDC Wonder database text file. Note that the year is different for each data download from the original database."Dataset: Underlying Cause of Death, 1999-2017""Query Parameters:""Drug/Alcohol Induced Causes: Drug poisonings (overdose) Unintentional (X40-X44)""States: Tennessee (47)""Year/Month: 1999""Group By: County""Show Totals: True""Show Zero Values: False""Show Suppressed: False""Calculate Rates Per: 100,000""Rate Options: Default intercensal populations for years 2001-2009 (except Infant Age Groups)""---""Help: See http://wonder.cdc.gov/wonder/help/ucd.html for more information.""---""Query Date: Aug 19, 2019 10:22:15 PM""1. Rows with suppressed Deaths are hidden, but the Deaths and Population values in those rows are included in the totals. Use""Quick Options above to show suppressed rows.""---"Caveats:"1. Data are Suppressed when the data meet the criteria for confidentiality constraints. More information:""http://wonder.cdc.gov/wonder/help/ucd.html#Assurance of Confidentiality.""2. Death rates are flagged as Unreliable when the rate is calculated with a numerator of 20 or less. More information:""http://wonder.cdc.gov/wonder/help/ucd.html#Unreliable.""3. The population figures for year 2017 are bridged-race estimates of the July 1 resident population, from the Vintage 2017""postcensal series released by NCHS on June 27, 2018. The population figures for year 2016 are bridged-race estimates of the July""1 resident population, from the Vintage 2016 postcensal series released by NCHS on June 26, 2017. The population figures for""year 2015 are bridged-race estimates of the July 1 resident population, from the Vintage 2015 postcensal series released by NCHS""on June 28, 2016. The population figures for year 2014 are bridged-race estimates of the July 1 resident population, from the""Vintage 2014 postcensal series released by NCHS on June 30, 2015. The population figures for year 2013 are bridged-race""estimates of the July 1 resident population, from the Vintage 2013 postcensal series released by NCHS on June 26, 2014. The""population figures for year 2012 are bridged-race estimates of the July 1 resident population, from the Vintage 2012 postcensal""series released by NCHS on June 13, 2013. The population figures for year 2011 are bridged-race estimates of the July 1 resident""population, from the Vintage 2011 postcensal series released by NCHS on July 18, 2012. Population figures for 2010 are April 1""Census counts. The population figures for years 2001 - 2009 are bridged-race estimates of the July 1 resident population, from""the revised intercensal county-level 2000 - 2009 series released by NCHS on October 26, 2012. Population figures for 2000 are""April 1 Census counts. Population figures for 1999 are from the 1990-1999 intercensal series of July 1 estimates. Population""figures for the infant age groups are the number of live births.
Note: Rates and population figures for years 2001 -""2009 differ slightly from previously published reports, due to use of the population estimates which were available at the time""of release.""4. The population figures used in the calculation of death rates for the age group 'under 1 year' are the estimates of the""resident population that is under one year of age. More information: http://wonder.cdc.gov/wonder/help/ucd.html#Age Group."

BackgroundVirtual overdose monitoring services or Mobile Overdose Response Services (MORS) are novel virtual harm reduction tools which have gained popularity as an adjunct public health intervention especially for those who cannot access harm reduction resources through traditional means. At this time, relatively little is known about their ability to reach their goals of reducing overdose mortality. Our study aims to summarize the potential effectiveness of various MORS collectively to avoid potential mortality from a drug poisoning event/drug overdose.MethodsUtilizing publicly available data from various MORS alongside some usage data provided by these services for this study, we model the impact of these services on fatal drug poisoning/overdose. In order to calculate the number of deaths averted, a Monte Carlo simulation was used to calculate point estimates with 95% confidence for fatal drug poisonings/drug overdose potentially averted through the utilization of various MORS.ResultsFrom the earliest mention of MORS in current literature (2019), a total of 299 drug poisoning/overdose events occurred across these services. Noting the broad range of mortality statistics available in current literature, these technologies have potentially prevented between 33 to 243 deaths. Our Monte Carlo estimates 135 potentially fatal drug poisonings/overdose were overall averted by the various MORS.ConclusionsWhile there is yet to be a robust data set proving the effectiveness of these services, conservative estimates show that MORS can reduce mortality associated with substance use and therefore should be considered as a viable harm-reduction strategy but as an adjunct to more established harm reduction services such as supervised consumption sites and supervised injection facilities. While more research is needed, clinicians and practitioners should consider the suggestion of these tools for patients who use drugs.

Rank, number of deaths, percentage of deaths, and age-specific mortality rates for the leading causes of death, by age group and sex, 2000 to most recent year.

This data set depicts unintentional overdose deaths by county for Tennessee from 1999-2017.Data was compiled from the CDC Wonder database for each year and combined into a single spreadsheet. Each year has both a death field and a rate of fatalities per 100,000 people. The CDC does not publish the number of fatalities by county if the total is less than 10 in a given year. The CDC does not post a rate of fatalities if the total number of deaths per county is less than 20. The population field contains estimates from 2018 and is NOT the data used to generate the rates over time.The following details are copied directly from the CDC Wonder database text file. Note that the year is different for each data download from the original database."Dataset: Underlying Cause of Death, 1999-2017""Query Parameters:""Drug/Alcohol Induced Causes: Drug poisonings (overdose) Unintentional (X40-X44)""States: Tennessee (47)""Year/Month: 1999""Group By: County""Show Totals: True""Show Zero Values: False""Show Suppressed: False""Calculate Rates Per: 100,000""Rate Options: Default intercensal populations for years 2001-2009 (except Infant Age Groups)""---""Help: See http://wonder.cdc.gov/wonder/help/ucd.html for more information.""---""Query Date: Aug 19, 2019 10:22:15 PM""1. Rows with suppressed Deaths are hidden, but the Deaths and Population values in those rows are included in the totals. Use""Quick Options above to show suppressed rows.""---"Caveats:"1. Data are Suppressed when the data meet the criteria for confidentiality constraints. More information:""http://wonder.cdc.gov/wonder/help/ucd.html#Assurance of Confidentiality.""2. Death rates are flagged as Unreliable when the rate is calculated with a numerator of 20 or less. More information:""http://wonder.cdc.gov/wonder/help/ucd.html#Unreliable.""3. The population figures for year 2017 are bridged-race estimates of the July 1 resident population, from the Vintage 2017""postcensal series released by NCHS on June 27, 2018. The population figures for year 2016 are bridged-race estimates of the July""1 resident population, from the Vintage 2016 postcensal series released by NCHS on June 26, 2017. The population figures for""year 2015 are bridged-race estimates of the July 1 resident population, from the Vintage 2015 postcensal series released by NCHS""on June 28, 2016. The population figures for year 2014 are bridged-race estimates of the July 1 resident population, from the""Vintage 2014 postcensal series released by NCHS on June 30, 2015. The population figures for year 2013 are bridged-race""estimates of the July 1 resident population, from the Vintage 2013 postcensal series released by NCHS on June 26, 2014. The""population figures for year 2012 are bridged-race estimates of the July 1 resident population, from the Vintage 2012 postcensal""series released by NCHS on June 13, 2013. The population figures for year 2011 are bridged-race estimates of the July 1 resident""population, from the Vintage 2011 postcensal series released by NCHS on July 18, 2012. Population figures for 2010 are April 1""Census counts. The population figures for years 2001 - 2009 are bridged-race estimates of the July 1 resident population, from""the revised intercensal county-level 2000 - 2009 series released by NCHS on October 26, 2012. Population figures for 2000 are""April 1 Census counts. Population figures for 1999 are from the 1990-1999 intercensal series of July 1 estimates. Population""figures for the infant age groups are the number of live births.
Note: Rates and population figures for years 2001 -""2009 differ slightly from previously published reports, due to use of the population estimates which were available at the time""of release.""4. The population figures used in the calculation of death rates for the age group 'under 1 year' are the estimates of the""resident population that is under one year of age. More information: http://wonder.cdc.gov/wonder/help/ucd.html#Age Group."

During 2024, there were a total of 7,146 deaths from opioid overdose in Canada, 2,231 of which occurred in the province of Ontario. This statistic shows the number of deaths from opioid overdose in Canada in 2024, by province. Opioid Use and Misuse Opioids are commonly prescribed as both short-term and long-term pain management strategies. Unfortunately, opioids are sometimes used problematically, including taking increased amounts, tampering with the route of administration, or using with the goal to improve mood, all of which can lead to addiction, overdose, and even death. In 2023, there were around 6,462 hospitalizations in Canada due to opioid poisoning. Opioid Crisis in Canada Among Canadian adults, the majority view the opioid issues of the country as a serious problem or a crisis. Moreover, many opioid deaths also involve the use of a stimulant, which adds to the polysubstance nature of the opioid crisis. Efforts against the opioid crisis in Canada are multi-faceted. One way is focused on reducing possible harm from using illicit opioid sources such as heroin or other street opioids through the use of opioid agonist treatment methods including methadone and naloxone.

At around ** billion U.S. dollars, the requested total U.S. drug control budget for 2026 was significantly lower than in previous years. This was mostly because for several agencies, the budget requests had still to be defined, as of the time of publication of the report. This statistic depicts the total federal drug control spending in the United States from FY 2012 to FY 2026, in million U.S. dollars. U.S. drug control spending In the United States, around half of the requested budget for federal drug control spending for FY 2025 was requested for treatment of substance use disorders; the remaining budget was distributed amongst various governmental departments for prevention, interdiction, and law enforcement. In particular, the largest amount of drug control treatment funding in FY 2025 within the Department of Health and Human Services was spent by the Centers for Medicare and Medicaid Services, followed by the Substance Abuse and Mental Health Services Administration. Drug control and the opioid epidemic The misuse of prescription drugs and the opioid epidemic are a major focus of U.S. drug control strategies and spending. In the U.S., the top controlled prescription drugs distributed are hydrocodone and oxycodone, both potentially addictive opioid analgesics that can be misused and sold illegally. In 2010-2019, efforts to reduce illegal sales of opioid narcotics in the U.S. have managed to reduce the amount of opioids diverted from the legal market by over half. Unfortunately, misusing opioids and synthetic variants such as heroin can be life-threatening; death rates due to opioid overdoses are continuing to rise.

In 2023, there were 338 drug overdose deaths recorded in the Netherlands. The number of casualties was lowest in 2010, while 2023 represented the highest annual figure. In the last six years, a record high in drug deaths was reached. Opiates, cocaine and other dangerous drugs  Many drug deaths in the Netherlands were caused by opiates. Of the total 338 casualties in 2023, 178 died because of opiate use. By comparison, there were 63 cocaine deaths that year. The number of cocaine-related deaths in the country in the past decade have also notably increased. Cocaine use on the rise According to the Trimbos survey on drug use, cocaine use has increased in the Netherlands. Whereas in 1997, 2.6 percent of the respondents stated to have used cocaine at least once in their lives, by 2022 this had grown to over six percent. Of the survey participants, one percent reported having used cocaine in the past month, a slight change in comparison to earlier years as well.