HIV/AIDS deaths in the U.S. have dropped significantly in recent years. In 1995, the death rate from HIV per 100,000 people was 16.2. That number has since decreased to 1.3 per 100,000 as of 2022. The reduction in the HIV death rate in the U.S. can be attributed to an increase in access to HIV medications. HIV/AIDS in the U.S. Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) cause a systemic viral infection that damages the immune system. AIDS is a syndrome that is caused by HIV. AIDS is when the immune system is severely weakened by HIV and the body can no longer fight off infections. The number of AIDS diagnoses in the U.S. has decreased significantly in recent years. Among all U.S. states, Georgia, followed by Louisiana, had the highest rates of new HIV diagnoses in 2021. HIV/AIDS treatments in the U.S. HIV/AIDS treatments include antiretroviral medications to reduce the levels of HIV within the body. The largest funders for HIV/AIDS medications and research are the National Institutes of Health (NIH) and the Ryan White Program. The top HIV drug worldwide, based on revenue generated in 2023 was Biktarvy. Around the world, access to antiretroviral treatment has increased dramatically in recent years, a huge step in reducing the number of HIV-related deaths. There is currently no cure for HIV.

UNAIDS estimated that there were some 630,000 people worldwide that died from acquired immune deficiency syndrome (AIDS) in 2023. This statistic depicts the total number of annual AIDS-related deaths worldwide from 2000 to 2023. HIV/AIDS burden A majority of countries with the highest burden due to HIV and AIDS are in Africa- in 2023, the highest number of AIDS-related deaths occurred in South Africa and Nigeria and the highest prevalence of HIV was found in Eswatini. Although access to life-saving antiretroviral therapy treatment (ART) has increased globally over recent years, many individuals living with HIV still lack access to ART. Barriers and interventions In part due to the development of ART, the number of people living with HIV worldwide is continuing to increase, reaching almost 40 million in 2023. Important public health measures to combat the burden of the disease include a combination of biomedical and behavioral interventions such as pre- and post-exposure prophylaxis, and context-specific structural interventions to reduce barriers to supplies and education. One prominent barrier faced by those living with HIV is stigma, which can often cause disadvantages in many areas of life, including employment, use of health services, and social support.

In 2023, South Africa and Nigeria had the highest number of deaths due to AIDS worldwide, with around 50 thousand and 45 thousand such deaths, respectively. African countries account for eight of the top 10 countries with the highest number of AIDS-related deaths worldwide. AIDS-related deaths worldwide have been gradually declining over the past decade, decreasing from 1.3 million deaths in 2010 to 630 thousand deaths in 2023. HIV/AIDS HIV (human immunodeficiency virus) is an infectious sexually transmitted disease that is transmitted via exposure to infected semen, blood, vaginal and anal fluids and breast milk. HIV weakens the human immune system, resulting in the affected person being unable to fight off opportunistic infections. The top 15 countries worldwide with the highest prevalence of new HIV infections as of 2023 were all African. HIV treatment Although there is currently no effective cure for HIV, death can be prevented by taking HIV antiretroviral therapy (ART). Access to antiretroviral therapy worldwide has significantly increased in the past decade. As of 2023, around 30.7 million people with HIV worldwide were receiving ART. The leading countries with the highest percentage of HIV-infected children who were receiving ART were Eswatini, Kenya, and Lesotho.

In 2022, the death rate from HIV was highest among African Americans, with around 19 deaths per 100,000 population. This statistic shows the death rate from HIV in the U.S. in 2022, by race and ethnicity, per 100,000 population.

In 2022, there were 2.1 male deaths from the HIV disease per 100,000 inhabitants in the United States. This statistic shows the death rate for the human immunodeficiency virus (HIV) disease among the U.S. population from 1987 to 2022, by gender.

In 2022, the death rate from HIV was highest among those aged 60 to 64 years, with around 14.8 deaths per 100,000 population. This statistic shows the death rate from HIV in the U.S. in 2022, by age, per 100,000 population.

In 2023, around 0.3 out of 100 thousand Canadians died from HIV. In 2000, the death rate stood at approximately 1.7 deaths per 100,000. This statistic displays the age-standardized death rates in Canada for HIV from 2000 to 2023. HIV in Canada Human immunodeficiency virus (HIV) is a contagious virus that weakens the body’s immune system. Without treatment, over time the damage caused by the virus can progress to AIDS, where the body is unable to fight other infections, leading to death. In Canada, the number of newly reported cases of HIV has fluctuated between around 1,500 and 2,500 per year over the past twenty years, with the rate of reported cases around 4.71 per 100,000 population in 2022. HIV worldwide Although the number of people living with HIV is rising worldwide, the number of new HIV infections has decreased by nearly half in the past twenty years. This is due to better treatment, especially antiretroviral therapy, which allows those with HIV to live longer, healthier lives. Global health organizations have established strategies to try to eliminate AIDS as a public health threat, focusing mostly on increasing awareness and early identification of cases, providing methods to avoid passing on the virus, as well as providing treatment with the goal of viral suppression. Although there is no known cure, the majority of the funding for HIV/AIDS research and development over recent years has been provided for further work on creating HIV vaccines.

In 2023, India reported an estimate of 36 thousand annual AIDS related deaths (ARD) across the country. Male deaths from HIV/AIDS amounted to nearly 24 thousand, accounting for approximately 67 percent of AIDS related deaths in India that year.

In 2022, the District of Columbia had the highest HIV disease death rate among all U.S. states where 6.2 out of 100,000 inhabitants died due to HIV in 2022. This statistic shows the U.S. states with the highest HIV disease death rates in 2022.

In 2022, Jamaica and Suriname were the countries with the highest number of deaths per thousand people due to HIV/AIDS in Latin America and the Caribbean, with an estimate of 0.38 deaths per 1,000 people. Belize followed, with around 0.26 deaths per 1,000 people. Meanwhile, Peru and Ecuador had the lowest rate of HIV-related deaths in the region that year. That year, the Latin American country with the highest number of people living with HIV was Brazil.

In 2024, the estimated number of deaths from AIDS in South Africa reached 68,406. This was slightly higher compared to the previous year, when the AIDS related deaths in the country amounted to 68,382. From 2006 onwards (except in 2016), the number of AIDS-related deaths dropped annually.

In 2022, there were an estimated 40 thousand deaths due to HIV-related causes in India. That year, the number of AIDS deaths in Indonesia amounted to an estimated 26 thousand.

In 2022, there were 4.1 deaths per 100,000 people due to AIDS reported in Brazil, down from around 4.2 deaths per hundred thousand people a year earlier. The AIDS death rate in Brazil showed an overall decrease during the analyzed period, ranging from 5.7 deaths per 100,000 inhabitants in 2010, to four cases in every 100,000 people in 2020. In 2023, almost 11,000 people died from complications stemming from AIDS in the South American country.

Eswatini had the highest AIDS mortality rate in the world, at 2.55 per 1,000 population in 2023. This statistic presents the AIDS mortality rate in select African countries in 2023.

This statistics shows the death rate for the human immunodeficiency virus (HIV) disease among the male U.S. population by ethnicity, in 1987 and 2013. In 1987, there were 8.7 deaths among white males in the U.S. by the HIV disease per 100,000 inhabitants.

In 2022, a study found that men had higher HIV death rates than women among all age groups in Colombia. The death rate from HIV was highest for men aged 50 or older, with approximately 11.95 deaths per 100,000 population. Meanwhile, for women, the largest death rate from HIV was for those aged 25 to 49, with around 2.49 cases per 100,000 inhabitants. Colombia had an HIV prevalence rate of 0.4 percent among people between 15 and 49 years in 2020, similar to Uruguay and Argentina.

In 2023, more females than males died from HIV or AIDS in both African regions displayed, with 10,000 more deaths among women and girls in the East and Southern Africa region. This statistic shows the number of deaths from HIV/AIDS in Africa in 2023, by region and gender.

As of 2021, 1.9 million people in Nigeria were living with HIV. That year, the number of deaths due to AIDS amounted to 51 thousand, including both adults and children. The highest number of deaths was recorded among female adults, with 17 thousand deaths.

In 2023, there were 37 deaths caused by the human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) in Malaysia, a decrease from 48 deaths caused by the disease the year before. The number of HIV/AIDS related deaths in Malaysia has been decreasing since 2014, when the number was at 117 deaths.

In 2019, Guyana was the country with the highest number of age-adjusted deaths per 100,000 people due to HIV/AIDS in Latin America and the Caribbean, with nearly 35 deaths per 100,000 population. Belize ranked second, with almost 34 deaths per 100,000 thousand people due to the disease. Meanwhile, approximately two individuals per 100,000 people died from HIV/AIDS in Bolivia that year.