18 datasets found
  1. Weight of individuals in England 1998-2022, by gender

    • statista.com
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    Statista, Weight of individuals in England 1998-2022, by gender [Dataset]. https://www.statista.com/statistics/333862/weight-of-individuals-by-gender-in-england/
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    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    England
    Description

    In England, there has been fairly significant increase in the mean weight of the population over the last quarter-century. In 1998, the mean weight was under 81 kilograms for men and around 68 kilograms for women. By 2022, the mean weight of men was 85.8 kilograms and the mean weight of women was 72.8 kilograms.

  2. Mean body mass index in England 2022, by gender and age

    • statista.com
    Updated Sep 24, 2024
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    Statista (2024). Mean body mass index in England 2022, by gender and age [Dataset]. https://www.statista.com/statistics/375886/adult-s-body-mass-index-by-gender-and-age-in-england/
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    Dataset updated
    Sep 24, 2024
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2022
    Area covered
    United Kingdom (England)
    Description

    In 2022, men aged 55 to 64 years had an average body mass index (BMI) of 29 kg/m2 and women in the same age group had a BMI of 28.8 kg/m2, the highest mean BMI across all the age groups. Apart from individuals aged 16 to 24 years, every demographic in England had an average BMI which is classified as overweight.An increasing problem It is shown that the mean BMI of individuals for both men and women has been generally increasing year-on-year in England. The numbers show in England, as in the rest of the United Kingdom (UK), that the prevalence of obesity is an increasing health problem. The prevalence of obesity in women in England has increased by around nine percent since 2000, while for men the share of obesity has increased by six percent. Strain on the health service Being overweight increases the chances of developing serious health problems such as diabetes, heart disease and certain types of cancers. In the period 2019/20, England experienced over 10.7 thousand hospital admissions with a primary diagnosis of obesity, whereas in 2002/03 this figure was only 1,275 admissions. Furthermore, the number of bariatric surgeries taking place in England, particularly among women, has significantly increased over the last fifteen years. In 2019/20, over 5.4 thousand bariatric surgery procedures were performed on women and approximately 1.3 thousand were carried out on men.

  3. Weight distribution among adults in the United Kingdom (UK) 2015, by gender

    • statista.com
    Updated Nov 1, 2015
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    Statista (2015). Weight distribution among adults in the United Kingdom (UK) 2015, by gender [Dataset]. https://www.statista.com/statistics/505160/weight-distribution-among-adults-by-gender-united-kingdom-uk/
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    Dataset updated
    Nov 1, 2015
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    Aug 2015
    Area covered
    United Kingdom
    Description

    This statistic displays the breakdown of body weight class among men and women in the United Kingdom (UK) in 2015. Of respondents, 39 percent of men and 46 percent of women had a healthy body weight.

  4. d

    Statistics on Obesity, Physical Activity and Diet (replaced by Statistics on...

    • digital.nhs.uk
    Updated May 5, 2020
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    (2020). Statistics on Obesity, Physical Activity and Diet (replaced by Statistics on Public Health) [Dataset]. https://digital.nhs.uk/data-and-information/publications/statistical/statistics-on-obesity-physical-activity-and-diet
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    Dataset updated
    May 5, 2020
    License

    https://digital.nhs.uk/about-nhs-digital/terms-and-conditionshttps://digital.nhs.uk/about-nhs-digital/terms-and-conditions

    Time period covered
    Apr 1, 2018 - Dec 31, 2019
    Description

    This report presents information on obesity, physical activity and diet drawn together from a variety of sources for England. More information can be found in the source publications which contain a wider range of data and analysis. Each section provides an overview of key findings, as well as providing links to relevant documents and sources. Some of the data have been published previously by NHS Digital. A data visualisation tool (link provided within the key facts) allows users to select obesity related hospital admissions data for any Local Authority (as contained in the data tables), along with time series data from 2013/14. Regional and national comparisons are also provided. The report includes information on: Obesity related hospital admissions, including obesity related bariatric surgery. Obesity prevalence. Physical activity levels. Walking and cycling rates. Prescriptions items for the treatment of obesity. Perception of weight and weight management. Food and drink purchases and expenditure. Fruit and vegetable consumption. Key facts cover the latest year of data available: Hospital admissions: 2018/19 Adult obesity: 2018 Childhood obesity: 2018/19 Adult physical activity: 12 months to November 2019 Children and young people's physical activity: 2018/19 academic year

  5. l

    Supplementary files for Are associations of adulthood overweight and obesity...

    • repository.lboro.ac.uk
    • datasetcatalog.nlm.nih.gov
    docx
    Updated May 29, 2025
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    Will Johnson; Tom Norris; Natalie Pearson; Emily Petherick; James King; Scott Willis; Rebecca Hardy; Susan Paudel; Emma Haycraft; Jennifer L Baker; Mark Hamer; David Stensel; Kate Tilling; Tom Richardson (2025). Supplementary files for Are associations of adulthood overweight and obesity with all-cause mortality, cardiovascular disease, and obesity-related cancer modified by comparative body weight at age 10 years in the UK Biobank study? [Dataset]. http://doi.org/10.17028/rd.lboro.28151681.v1
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    docxAvailable download formats
    Dataset updated
    May 29, 2025
    Dataset provided by
    Loughborough University
    Authors
    Will Johnson; Tom Norris; Natalie Pearson; Emily Petherick; James King; Scott Willis; Rebecca Hardy; Susan Paudel; Emma Haycraft; Jennifer L Baker; Mark Hamer; David Stensel; Kate Tilling; Tom Richardson
    License

    https://library.midwestern.edu/copyright_statement/homehttps://library.midwestern.edu/copyright_statement/home

    Description

    Supplementary files for article "Are associations of adulthood overweight and obesity with all-cause mortality, cardiovascular disease, and obesity-related cancer modified by comparative body weight at age 10 years in the UK Biobank study?"Article abstractObjectiveAdults living with overweight or obesity do not represent a single homogenous group in terms of mortality and disease risks. The aim of our study was to evaluate how the associations of adulthood overweight and obesity with mortality and incident disease are modified by (i.e., differ according to) self-reported childhood body weight categories.MethodsThe sample comprised 191,181 men and 242,806 women aged 40-69 years (in 2006-2010) in the UK Biobank. The outcomes were all-cause mortality, incident cardiovascular disease (CVD), and incident obesity-related cancer. Cox proportional hazards regression models were used to estimate how the associations with the outcomes of adulthood weight status (normal weight, overweight, obesity) differed according to perceived body weight at age 10 years (about average, thinner, plumper). To triangulate results using an approach that better accounts for confounding, analyses were repeated using previously developed and validated polygenic risk scores (PRSs) for childhood body weight and adulthood BMI, categorised into three-tier variables using the same proportions as in the observational variables.ResultsIn both sexes, adulthood obesity was associated with higher hazards of all outcomes. However, the associations of obesity with all-cause mortality and incident CVD were stronger in adults who reported being thinner at 10 years. For example, obesity was associated with a 1.28 (1.21, 1.35) times higher hazard of all-cause mortality in men who reported being an average weight child, but among men who reported being a thinner child this estimate was 1.63 (1.53, 1.75). The ratio between these two estimates was 1.28 (1.17, 1.40). There was also some evidence that the associations of obesity with all-cause mortality and incident CVD were stronger in adults who reported being plumper at 10 years. In genetic analyses, however, there was no evidence that the association of obesity (according to the adult PRS) with mortality or incident CVD differed according to childhood body size (according to the child PRS). For incident obesity-related cancer, the evidence for effect modification was limited and inconsistent between the observational and genetic analyses.ConclusionsGreater risks for all-cause mortality and incident CVD in adults with obesity who perceive themselves to have been a thinner or plumper than average child may be due to confounding and/or recall bias.

  6. Average birth weight and height for sample population percentiles for males...

    • plos.figshare.com
    xls
    Updated Jun 5, 2023
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    Piers Dawes; Karen J. Cruickshanks; David R. Moore; Heather Fortnum; Mark Edmondson-Jones; Abby McCormack; Kevin J. Munro (2023). Average birth weight and height for sample population percentiles for males and females. [Dataset]. http://doi.org/10.1371/journal.pone.0136590.t002
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    xlsAvailable download formats
    Dataset updated
    Jun 5, 2023
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Piers Dawes; Karen J. Cruickshanks; David R. Moore; Heather Fortnum; Mark Edmondson-Jones; Abby McCormack; Kevin J. Munro
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    Average birth weight and height for sample population percentiles for males and females.

  7. d

    Health Survey for England

    • digital.nhs.uk
    pdf
    Updated Dec 10, 2014
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    (2014). Health Survey for England [Dataset]. https://digital.nhs.uk/data-and-information/publications/statistical/health-survey-for-england
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    pdf(779.8 kB), pdf(509.2 kB), pdf(137.3 kB), pdf(433.0 kB), pdf(647.4 kB), pdf(1.4 MB), pdf(859.2 kB), pdf(849.7 kB), pdf(5.3 MB), pdf(676.6 kB), pdf(656.8 kB), pdf(755.8 kB), pdf(662.2 kB), pdf(806.7 kB), pdf(82.5 kB), pdf(318.3 kB)Available download formats
    Dataset updated
    Dec 10, 2014
    License

    https://digital.nhs.uk/about-nhs-digital/terms-and-conditionshttps://digital.nhs.uk/about-nhs-digital/terms-and-conditions

    Time period covered
    Jan 1, 2013 - Dec 31, 2013
    Area covered
    England
    Description

    The Health Survey for England series was designed to monitor trends in the nation's health, to estimate the proportion of people in England who have specified health conditions, and to estimate the prevalence of certain risk factors and combinations of risk factors associated with these conditions. The surveys provide regular information that cannot be obtained from other sources on a range of aspects concerning the public's health and many of the factors that affect health. Each survey in the series includes core questions and measurements (such as blood pressure, height and weight, and analysis of blood and saliva samples), as well as modules of questions on topics that vary from year to year. Four topics are reported for the first time this year: medicines, eye care, end of life care and a comparison of the health of shift workers and non-shift workers. Many chapters in this report contain more charts and less detailed descriptive text than in previous survey reports. We would very much welcome readers' views about this change. The Health Survey for England has been carried out since 1994 by the Joint Health Surveys Unit of NatCen Social Research and the Research Department of Epidemiology and Public Health at UCL (University College London). A total of 8,795 adults and 2,185 children were interviewed in 2013. Please note this release was revised on 11 December 2014. This revision corrected Chapter 7 figures for median and mean number of portions of fruit and vegetables and the associated standard errors in the tables and corrected the 2013 data points for men and women aged 33-64 in Figure 10P - Morbid Obesity Prevalence, 1993-2013.

  8. Waist circumference in England 2022, by gender and age

    • statista.com
    Updated Jul 17, 2025
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    Statista (2025). Waist circumference in England 2022, by gender and age [Dataset]. https://www.statista.com/statistics/375954/waist-circumference-by-gender-and-age-in-england/
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    Dataset updated
    Jul 17, 2025
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2022
    Area covered
    England
    Description

    In 2022, the mean waist circumference in England among the age group of 65 to 74 years was 104.5 centimeters for men and 91.3 centimeters for women. The was the age group with the largest average waist circumference among men, while the highest among women was reported in the age groups 55 to 64 years and above 75 years. Age and gender differences in very high waist circumference The 2022 data shows that the age group between 65 and 74 years in England had the largest share of men with very high waist circumference at 54 percent, whereas 56 percent of the women in the age group from 55 to 64 years had the same classification. Interestingly, both men and women. The youngest age group, 16 to 34 years, had the smallest share of individuals with very high waist circumference for both genders, with men at 17 percent and women at 34 percent. Obesity trends and health implications The increasing waist sizes align with broader obesity trends in England. In 2022, the mean body mass index (BMI) for both men and women was 27.6, which falls into the overweight category. This is part of a steady upward trend since 1998. The prevalence of obesity has also risen, with 30 percent of women and 28 percent of men classified as obese in 2022, up from 21 percent for both genders in 2000. Additionally, 39 percent of men and 31 percent of women were classified as overweight in 2022, while the share of individuals classified as having normal body weight was 31 percent among men and 37 percent among women in England.

  9. London Health Inequalities Strategy Indicators - Dataset - data.gov.uk

    • ckan.publishing.service.gov.uk
    Updated Dec 6, 2018
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    ckan.publishing.service.gov.uk (2018). London Health Inequalities Strategy Indicators - Dataset - data.gov.uk [Dataset]. https://ckan.publishing.service.gov.uk/dataset/london-health-inequalities-strategy-indicators
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    Dataset updated
    Dec 6, 2018
    Dataset provided by
    CKANhttps://ckan.org/
    Area covered
    London
    Description

    The Mayors Health Inequalities Strategy sets out his plans to tackle unfair differences in health to make London a healthier, fairer city. This dataset reports the 14 headline population health indicators that will be used to monitor London’s progress in reducing health inequalities over the next ten years. The themes of the indicators are listed below. The measures will monitor an identified inequality gap between defined populations. Healthy life expectancy at birth – male Healthy life expectancy at birth – female Children born with low birth weight School readiness among children Excess weight in children at age 10-11 (year 6) Excess mortality in adults with serious mental illness Suicide Mortality caused by Particulate Matter (PM2.5) Employment Feeling of belonging to a community (provisional) HIV late diagnosis People diagnosed with TB Adults walking or cycling for two periods of ten minutes each day Smoking

  10. Weight classification based on BMI in England 2022, by gender

    • statista.com
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    Statista, Weight classification based on BMI in England 2022, by gender [Dataset]. https://www.statista.com/statistics/333870/obesity-prevalence-by-gender-in-england-uk/
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    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2022
    Area covered
    United Kingdom, England
    Description

    This statistics display the distribution of weight classification in England in 2022, based on self--reported body mass index (BMI). In this year, 39 percent of men and 31 percent of women were classed as being overweight. Those with a BMI of between 25 and 29.9 are classed as overweight.

  11. e

    Human obesity associated circulating sEVs proteomics

    • ebi.ac.uk
    Updated Feb 27, 2024
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    Keyang Xu (2024). Human obesity associated circulating sEVs proteomics [Dataset]. https://www.ebi.ac.uk/pride/archive/projects/PXD041236
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    Dataset updated
    Feb 27, 2024
    Authors
    Keyang Xu
    Variables measured
    Proteomics
    Description

    This clinical study was approved by the Ethics Committee at Hangzhou Xixi Hospital (Zhejiang province, China). A total of 11 males and 37 females were included in normal weight healthy control group (NC); 77 males and 19 females were included in BMI group. Normal weight healthy control group: BMI equals or less than 23 without acute and chronic diseases.; BMI group: BMI equals or above 25

  12. e

    Human plasma proteome of caloric restriction

    • ebi.ac.uk
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    Spyros Vernardis, Human plasma proteome of caloric restriction [Dataset]. https://www.ebi.ac.uk/pride/archive/projects/PXD038526
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    Authors
    Spyros Vernardis
    Variables measured
    Proteomics
    Description

    We recruited ten normal-weight healthy men using inclusion criteria as previously described (Collet et al 2017). All males were healthy and not obese or overweight (average age: 23.8 years, average BMI (kg/m2): 23.3). Participants at baseline consumed a balanced diet (50% carbohydrate, 30% fat, and 20% protein). During caloric restriction, volunteers consumed 10% of normal energy requirement (226 kcal/d) for two days, again balanced (50% carbohydrate, 30% fat, and 20% protein), with the same macronutrient composition. After caloric restriction, volunteers were offered three substantial ad libitum buffet meals per day (20 MJ = 4,777 kcal) and additional snacks (16 MJ = 3,821 kcal) between meals for 2 days. They were invited to eat freely until comfortably full; food consumption was covertly measured. We collected fasting plasma samples at 0800 AM at baseline, after CR and refeeding (RF).

  13. f

    Data_Sheet_1_Bodyweight and body condition scores of Australian British...

    • frontiersin.figshare.com
    xlsx
    Updated Oct 11, 2023
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    B. J. Murphy; M. A. Stevenson; C. S. Mansfield (2023). Data_Sheet_1_Bodyweight and body condition scores of Australian British shorthaired cats, 2008–2017.XLSX [Dataset]. http://doi.org/10.3389/fvets.2023.1241080.s001
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    xlsxAvailable download formats
    Dataset updated
    Oct 11, 2023
    Dataset provided by
    Frontiers
    Authors
    B. J. Murphy; M. A. Stevenson; C. S. Mansfield
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Area covered
    Australia, United Kingdom
    Description

    Obesity is the most common nutritional problem in companion animals today, and Australian British shorthair (BSH) cats have been shown to have a greater likelihood of being overweight relative to other cat breeds. The objectives of this research were to quantify bodyweight (BW) and body condition scores (BCSs) of BSH cats attending first opinion practice in Australia for the period 2008–2017 and to determine if: (1) being classified as overweight was associated with geographical location (urban versus rural and socio-economic index); and (2) BW recorded in the first 12 months of life was associated with length of life beyond 12 months. Electronic medical records from BSH cats were obtained from VetCompass Australia and used for BW and BCS analysis. Desexed males (n = 971) had the highest mean BW followed by entire males (n = 79), desexed females (n = 815), and entire females (n = 82). The desexed males, desexed females, and entire females had a mean BCS classified as overweight using a 1-to-9 point BCS scale. The entire male population was the only group with a mean BCS classified as ideal. No statistically significant association between BW and urban-rural status and no consistent trend between BW and socioeconomic deprivation was found. For cats with at least one BW measurement in the first 12 months of life that was ≤3.3 kg, the age when 20 percent of the group had died or were euthanised was 12.3 (95% CI 11.7 to 13.1) years. For cats with at least one BW measurement in the first 12 months of life that was ≥3.3 kg age, the age when 20 percent of the group had died or were euthanised was 6.6 (95% CI 5.2 to 6.6) years. This was a substantial clinical difference in survival. The study concluded that a large proportion of BSH cats attending first opinion veterinary clinics in Australia between 2008 and 2017 (48%) were classified as overweight. Cats less than 12 months of age that were greater than 3.3 kg had a shortened lifespan beyond 12 months of age compared with cats that were less than 3.3 kg.

  14. c

    Research Data supporting "Sex-specific effects of a maternal obesogenic diet...

    • repository.cam.ac.uk
    xls
    Updated Oct 27, 2023
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    Mort, Emily; Heritage, Sophie; Jones, Susan; Fowden, Abigail; Camm, Emily (2023). Research Data supporting "Sex-specific effects of a maternal obesogenic diet high in fat and sugar on offspring adiposity, growth and behaviour" [Dataset]. http://doi.org/10.17863/CAM.102134
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    xls(68612 bytes)Available download formats
    Dataset updated
    Oct 27, 2023
    Dataset provided by
    Apollo
    University of Cambridge
    Authors
    Mort, Emily; Heritage, Sophie; Jones, Susan; Fowden, Abigail; Camm, Emily
    Description

    This study investigates the effect of maternal diet-induced obesity in mice on maternal and offspring (male and female) nutrient intake, growth and adiposity, and investigates the effects of maternal diet on the behaviour of male and female offspring in four tasks. Figure 1 describes the nutrient intake of pre-pregnant, pregnant and lactating mice on a control versus a high fat and high sugar (HFHS) diet (mean and SD across cages). Figure 2 describes the body weight (mean and SD), the fat mass (individual mice) and lean mass (individual mice) of pre-pregnant, pregnant and lactating mice on a control versus a HFHS diet. Figure 3 describes the body mass and fractional growth rate of the male and female pre-weaning offspring (2 to 21 days of age) of mothers on the control versus HFHS diet. Figure 4 describes the nutrient intake of the male and female offspring, after weaning (21 to 91 days of age) of mothers on the control versus HFHS diet. Figure 5 describes the body weight (mean and SD), fractional growth rate (mean and SD) and fat & lean masses (individual mice) in the male and female offspring, after weaning (21 to 91 days of age) of mothers on the control versus HFHS diet. Figure 6 describes 4 measures of anxiety-related behaviour in the elevated plus maze by male and female offspring of mothers on the control versus HFHS diet. Figure 7 describes 4 measures of cognitive behaviour in the novel object recognition task by male and female offspring of mothers on the control versus HFHS diet. Figure Supplementary 2 describes 4 measurements of locomotion and anxiety-related behaviour int he open field task by male and female offspring of mothers on the control versus HFHS diet. Figure Supplementary 3 describes 2 measures of social preference behaviour of male and female offspring of mothers on the control versus HFHS diet. Table 1 gives all of the body weights, organ weights and fat deposit weights measured in this study in the pre-pregnant, pregnant and lactating female mice and int he male and female offspring.

  15. e

    Protein-restricted diet increases circulating FGF21 levels and necessitating...

    • ebi.ac.uk
    • data.niaid.nih.gov
    Updated Apr 22, 2025
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    Natalie Krahmer (2025). Protein-restricted diet increases circulating FGF21 levels and necessitating an increase in energy intake to maintain body weight in healthy human individuals [Dataset]. https://www.ebi.ac.uk/pride/archive/projects/PXD047177
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    Dataset updated
    Apr 22, 2025
    Authors
    Natalie Krahmer
    Variables measured
    Proteomics
    Description

    Dietary protein restriction has been shown to increase energy expenditure and to improve insulin sensitivity in mice, but it is unknown whether humans exhibit similar phenotype to a prolonged eucaloric protein-restricted diet that meet daily protein minimum requirements. We hypothesize that a protein-restricted diet would necessitate an increase in energy intake in order to maintain body weight in healthy, lean men. We designed an overall amino acid diluted diet meeting the requirement for daily protein intake and essential amino acids. Healthy, young, lean men adhered to a protein-restricted, high-carbohydrate diet (LPHC: protein 9E%, 70E% carbohydrate, and 21E% fat) or a protein-restricted, high-fat diet (LPHF: 9E% protein, 50E% fat, and 40E% carbohydrate) for 5 weeks, followed by another 5 weeks on a higher, standard protein diet (HPD: 18E% protein), reflecting their habitual diet. The diets were eucaloric, and energy provision was adjusted to maintain body weight throughout the interventions. In addition, wild type (WT), and FGF21 knockout mice were also fed LPHC, LPHF diets, or a standard higher diet (HPD) for a total of 10 weeks. Our results showed that prolonged eucaloric LPHC and LPHF diets necessitated a daily increase of 20-21% (2.5 MJ) in food intake to maintain body weight compared to pre-intervention in healthy, lean men. Additionally, fasting plasma FGF21 levels increased from 90±125 pg/ml and 78±34 pg/ml to 257±99 pg/ml and 160±52 pg/ml at the end of the LPHC and LPHF, respectively. Furthermore, proteomic analysis revealed adaptations in the respiratory chain in human adipose tissue after 5-week protein-restricted diets. This was found to be dependent on FGF21 in mice, indicating increased energy utilization through alternative UCP1-independent futile cycle pathways likely mediated by FGF21. Moreover, whole-body insulin sensitivity, measured by a hyperinsulinemic-euglycemic clamp, was increased by 16% after the LPHC intervention while maintained after the LPHF intervention, despite the high fat intake. These findings suggest that a protein-restricted diet could serve as a promising approach to prevent weight gain and comorbidities associated with obesity.

  16. Body weight measurements made pre- and post-expedition in the UK and during...

    • plos.figshare.com
    xls
    Updated Oct 10, 2024
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    Adrian J. Wilson; Robert M. Gifford; Henry Crosby; Sarah Davey; Natalie Taylor; Mike Eager; C. Doug Thake; Christopher H. E. Imray (2024). Body weight measurements made pre- and post-expedition in the UK and during the expedition itself together with the energy expenditure assuming the difference was due to change in fat weight. [Dataset]. http://doi.org/10.1371/journal.pone.0308804.t003
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    xlsAvailable download formats
    Dataset updated
    Oct 10, 2024
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Adrian J. Wilson; Robert M. Gifford; Henry Crosby; Sarah Davey; Natalie Taylor; Mike Eager; C. Doug Thake; Christopher H. E. Imray
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Area covered
    United Kingdom
    Description

    *It should be noted that the expedition ended on day 47 and the expedition end value was extrapolated from the measurements made on days 40 and 45.

  17. e

    Obesity significantly alters the human sperm proteome, with implications for...

    • ebi.ac.uk
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    Taylor Pini, Obesity significantly alters the human sperm proteome, with implications for fertility [Dataset]. https://www.ebi.ac.uk/pride/archive/projects/PXD014849
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    Authors
    Taylor Pini
    Variables measured
    Proteomics
    Description

    While obesity has links to poor semen parameters and reduced fertility, the causative links between obesity and male infertility are unclear, particularly on a molecular level. We investigated how obesity impacts the human sperm proteome, to further understand any implications for fertility. Sperm protein lysates from 5 healthy weight (BMI < 25) or obese (BMI>30) men were FASP digested, analysed by LC-MS/MS and quantitatively compared by label free quantification. Findings were confirmed for representative proteins by immunofluorescence staining. 2034 proteins were confidently identified, with 24 significantly less abundant (fold change <0.5) and 3 significantly more abundant (fold change >1.5)in sperm of obese men. These proteins were involved in a range of biological processes, including oxidative stress (GSS, NDUFS2, JAGN1, USP14, ADH5), inflammation (SUGT1, LTA4H), translation (EIF3F, EIF4A2, CSNK1G1), DNA damage repair (UBEA4) and sperm function (NAPA, RNPEP, BANF2). These results suggest that oxidative stress and inflammation are closely tied to reproductive dysfunction in obese men. These processes likely impact protein translation and folding during spermatogenesis, leading to poor sperm function and subfertility. The observation of these changes in normozoospermic men further suggests that traditional clinical semen assessment fails to detect important biological changes in spermatozoa which may compromise fertility.

  18. Overweight prevalence in England 2000-2022, by gender

    • statista.com
    Updated Oct 16, 2024
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    Statista (2024). Overweight prevalence in England 2000-2022, by gender [Dataset]. https://www.statista.com/statistics/334085/overweight-prevalence-england/
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    Dataset updated
    Oct 16, 2024
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2022
    Area covered
    United Kingdom
    Description

    In 2022, 39 percent of men and 31 percent of women in England were classed as overweight. At first glance, it may seem that the share of overweight people in England has decreased since the year 2000, but the share of obesity in England has increased since then, indicating that England’s problem with weight has gotten worse. Strain on health service due to obesity The number of hospital admissions as a result of obesity in England has increased alongside this rise in obesity. In the period 2019/20, over eight thousand women and 2.6 thousand men were admitted to hospital. An escalation from the admission levels in 2002/03. The highest number of admissions due to obesity were found in the age group 45 to 54 years, with over 3.1 thousand admissions in that age group. Situation in Scotland In Scotland in 2020, the mean Body Mass Index of women was 27.8 and for men it was 27.5. A BMI of over 25 is classed as overweight. While the share of adults classed as obese or morbidly obese in Scotland in this year was 30 percent for women and 26 percent for men.

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Statista, Weight of individuals in England 1998-2022, by gender [Dataset]. https://www.statista.com/statistics/333862/weight-of-individuals-by-gender-in-england/
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Weight of individuals in England 1998-2022, by gender

Explore at:
Dataset authored and provided by
Statistahttp://statista.com/
Area covered
England
Description

In England, there has been fairly significant increase in the mean weight of the population over the last quarter-century. In 1998, the mean weight was under 81 kilograms for men and around 68 kilograms for women. By 2022, the mean weight of men was 85.8 kilograms and the mean weight of women was 72.8 kilograms.

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