This statistic depicts the average male body weight of U.S. adults aged 20 years and over from 1999 to 2016. According to the data, the average male body weight for those aged 40-59 years was ***** in 1999-2000 and increased to ***** as of 2015-2016.

In 2024, around 40 percent of U.S. men reported weighing 200 pounds or more. This statistic shows the average self-reported weight among U.S. men from 1990 to 2024.

This statistic depicts the average body weight of U.S. men aged 20 years and over from 1999 to 2016, by ethnicity. According to the data, the average male body weight for those that identified as non-Hispanic white has increased from 192.3 in 1999-2000 to 202.2 in 2015-2016.

In 2024, the mean average weight reported by men was 195 pounds, while the mean average weight for women was 164 pounds. This statistic shows the mean self-reported weight among U.S. adults from 1990 to 2024, by gender, in pounds.

Surveys in which U.S. adults report their current weight have shown that the share of those reporting they weigh 200 pounds or more has increased over the past few decades. In 2024, around 28 percent of respondents reported their weight as 200 pounds or more, compared to 15 percent in 1990. However, the same surveys show the share of respondents who report they are overweight has decreased compared to figures from 1990. What percentage of the U.S. population is obese? Obesity is an increasing problem in the United States that is expected to become worse in the coming decades. As of 2023, around one third of adults in the United States were considered obese. Obesity is slightly more prevalent among women in the United States, and rates of obesity differ greatly by region and state. For example, in West Virginia, around 41 percent of adults are obese, compared to 25 percent in Colorado. However, although Colorado is the state with the lowest prevalence of obesity among adults, a quarter of the adult population being obese is still shockingly high. The health impacts of being obese Obesity increases the risk of developing a number of health conditions including high blood pressure, heart disease, type 2 diabetes, and certain types of cancer. It is no coincidence that the states with the highest rates of hypertension are also among the states with the highest prevalence of obesity. West Virginia currently has the third highest rate of hypertension in the U.S. with 45 percent of adults with the condition. It is also no coincidence that as rates of obesity in the United States have increased so have rates of diabetes. As of 2022, around 8.4 percent of adults in the United States had been diagnosed with diabetes, compared to six percent in the year 2000. Obesity can be prevented through a healthy diet and regular exercise, which also increases overall health and longevity.

BackgroundFew studies have examined weight transitions in contemporary multi-ethnic populations spanning early childhood through adulthood despite the ability of such research to inform obesity prevention, control, and disparities reduction.Methods and ResultsWe characterized the ages at which African American, Caucasian, and Mexican American populations transitioned to overweight and obesity using contemporary and nationally representative cross-sectional National Health and Nutrition Examination Survey data (n = 21,220; aged 2–80 years). Age-, sex-, and race/ethnic-specific one-year net transition probabilities between body mass index-classified normal weight, overweight, and obesity were estimated using calibrated and validated Markov-type models that accommodated complex sampling. At age two, the obesity prevalence ranged from 7.3% in Caucasian males to 16.1% in Mexican American males. For all populations, estimated one-year overweight to obesity net transition probabilities peaked at age two and were highest for Mexican American males and African American females, for whom a net 12.3% (95% CI: 7.6%-17.0%) and 11.9% (95% CI: 8.5%-15.3%) of the overweight populations transitioned to obesity by age three, respectively. However, extrapolation to the 2010 U.S. population demonstrated that Mexican American males were the only population for whom net increases in obesity peaked during early childhood; age-specific net increases in obesity were approximately constant through the second decade of life for African Americans and Mexican American females and peaked at age 20 for Caucasians.ConclusionsAfrican American and Mexican American populations shoulder elevated rates of many obesity-associated chronic diseases and disparities in early transitions to obesity could further increase these inequalities if left unaddressed.

This statistic depicts the average body weight of U.S. females aged 20 years and over from 1999 to 2016, by ethnicity. According to the data, the average female body weight for those that identified as non-Hispanic white has increased from ***** in ********* to ***** in *********.

BMI, body mass index; N, unweighted number; IQR, interquartile range.

BackgroundCurrent dietary guidelines recommend eating a variety of fruits and vegetables. However, based on nutrient composition, some particular fruits and vegetables may be more or less beneficial for maintaining or achieving a healthy weight. We hypothesized that greater consumption of fruits and vegetables with a higher fiber content or lower glycemic load would be more strongly associated with a healthy weight.Methods and FindingsWe examined the association between change in intake of specific fruits and vegetables and change in weight in three large, prospective cohorts of 133,468 United States men and women. From 1986 to 2010, these associations were examined within multiple 4-y time intervals, adjusting for simultaneous changes in other lifestyle factors, including other aspects of diet, smoking status, and physical activity. Results were combined using a random effects meta-analysis. Increased intake of fruits was inversely associated with 4-y weight change: total fruits -0.53 lb per daily serving (95% CI -0.61, -0.44), berries -1.11 lb (95% CI -1.45, -0.78), and apples/pears -1.24 lb (95% CI -1.62, -0.86). Increased intake of several vegetables was also inversely associated with weight change: total vegetables -0.25 lb per daily serving (95% CI -0.35, -0.14), tofu/soy -2.47 lb (95% CI, -3.09 to -1.85 lb) and cauliflower -1.37 lb (95% CI -2.27, -0.47). On the other hand, increased intake of starchy vegetables, including corn, peas, and potatoes, was associated with weight gain. Vegetables having both higher fiber and lower glycemic load were more strongly inversely associated with weight change compared with lower-fiber, higher-glycemic-load vegetables (p < 0.0001). Despite the measurement of key confounders in our analyses, the potential for residual confounding cannot be ruled out, and although our food frequency questionnaire specified portion size, the assessment of diet using any method will have measurement error.ConclusionsIncreased consumption of fruits and non-starchy vegetables is inversely associated with weight change, with important differences by type suggesting that other characteristics of these foods influence the magnitude of their association with weight change.

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Background: Obesity is a risk factor for many chronic diseases and the prevalence is increasing worldwide. Research suggests that sedentary behaviour (sitting) may be related to obesity. Aim: To examine the association between sitting time and obesity, while controlling for physical activity, in a large international sample. Subjects and methods: In total, 5338 adults from the UK, USA, Germany, Spain, Italy, France, Portugal, Austria and Switzerland self-reported their total daily sitting time, physical activity, age, height and weight. BMI (kg/m2), total physical activity (MET-minutes/week) and sitting time (hours/day) were derived. Participants were grouped into quartiles based on their daily sitting time (<4, 4–≤6, 6–≤8 and >8 hours/day) and logistic regression models explored the odds of being obese vs normal weight for each sitting time quartile. Results: Participants in the highest sitting time quartile (≥8 hours/day) had 62% higher odds of obesity compared to participants in the lowest quartile (<4 hours/day) after adjustment for physical activity and other confounding variables (OR = 1.62, 95% CI = 1.24–2.12, p < .01). Conclusion: Sitting time is associated with obesity in adults, independent of physical activity. Future research should clarify this association using objective measures of sitting time and physical activity to further inform health guidelines.

Maternal obesity has been associated with a higher risk of pregnancy-related complications in mothers and offspring; however, effective interventions have not yet been developed. We tested two common interventions, calorie restriction and pravastatin administration, during pregnancy in a rhesus macaque model with the hypothesis that these interventions would normalize metabolic dysregulation in pregnant mothers leading to an improvement in infant metabolic and cognitive/social development. A total of 19 obese mothers were assigned to either one of the two intervention groups (n=5 for calorie restriction; n=7 for pravastatin) or an obese control group (n=7) with no intervention, and maternal gestational samples and postnatal infant samples were compared with lean control mothers (n=6). Gestational calorie restriction normalized one-carbon metabolism dysregulation in obese mothers but altered energy metabolism in their offspring. Although administration of pravastatin during pregnancy tended to normalize blood cholesterol in the mothers, it potentially impacted the gut microbiome and kidney function of their offspring. In the offspring, both calorie restriction and pravastatin administration during pregnancy tended to normalize the activity of AMPK in the brain at 6 months, and while results of the Visual Paired-Comparison test, which measures infant recognition memory, were not significantly impacted by either of the interventions, gestational pravastatin administration, but not calorie restriction, tended to normalize anxiety assessed by the Human Intruder test. Although the two interventions tested in a non-human primate model led to some improvements in metabolism and/or infant brain development, negative impacts were also found in both mothers and infants. Our study emphasizes the importance of assessing gestational interventions for maternal obesity on both maternal and offspring long-term outcomes. Methods Study population Pregnant female rhesus macaques (Macaca mulatta) from an indoor breeding colony at the California National Primate Research Center with appropriate social behavior and previous successful pregnancies were enrolled. Animal handling was approved by the UC Davis Institutional Animal Care and Use Committee (IACUC) (#19299). A qualitative real-time PCR assay (Jimenez & Tarantal, 2003) was used to identify mothers with male fetuses to include in this study. Since obesity is defined as subjects with body fat above 30% for women, according to guidelines from the American Society of Bariatric Physicians, American Medical Association, and in some publications (Okorodudu et al., 2010; Shah & Braverman, 2012), a Body Condition Score (BCS) of 3.5 (32.8 % body fat on average (Summers et al., 2012)) was used as the cutoff. Therefore, mothers with BCS of 3.5 and above were categorized as obese. Obese mothers were randomly assigned to the Obese Control (OC) group, OR group (received calorie Restriction), or OP group (received Pravastatin). Mothers with BCS of 2.5 and below were assigned to the Lean Control (LC) group. The unbalanced sample size was because some mothers were removed from the analyses due to fetal deaths for unknown reasons, misidentification of a female fetus, different timing for study enrollment, or technical issues upon collecting samples. The number of animals was six for the LC, seven for the OC, five for the OR, and seven for the OP groups. Feeding, rearing, and interventions Adult female animals were provided monkey diet (High Protein Primate Diet Jumbo #5047; LabDiet, St. Louis, MO, USA) twice a day between 6–9 am and 1–3 pm. The calories were provided as 56% from carbohydrates, 30% from protein, and 13% from. Mothers in the LC, OC, and OP groups were fed nine biscuits twice a day once pregnancy was confirmed. Mothers in the OR group received a restricted supply of food once the pregnancy was detected and was maintained throughout pregnancy. The food restriction was set such that the average total weight increase would be 8% body weight from the last day before conception because the recommended total weight gain in the 2nd and 3rd trimesters is 5-9 kg for the average US woman with obesity who weighs 80 kg and is 1.6 m in height (Body Mass Index of 30), according to the Institute of Medicine 2009 guidelines (Institute of Medicine and National Research Council, 2009). During nursing of infants older than 4 months, all mothers were provided twelve biscuits. Fresh produce was provided biweekly, and water was provided ad libitum for all mothers. Mothers in the OP group were given pravastatin sodium (ApexBio Technology, Houston, TX, USA) at 20 mg/kg body weight prepared in a neutralized syrup (20 mg/mL sodium bicarbonate dissolved in a fruit-flavored syrup (Torani, San Leandro, CA, USA)) once a day from the time pregnancy was confirmed until delivery. The caloric value of the administration was made so as not to influence body weight or skew nutritional value of the diet among all treatment groups. Both interventions were applied only during gestation. Although most mothers were allowed to deliver naturally, cesarean delivery was performed for fetal indications when recommended by veterinarians (2 for each of the LC and OC groups, and 1 for the OP group). These mothers did not accept their infant following birth, so foster mothers were provided. Sample Collection and pre-processing prior to sample storage The animal caretakers and researchers who collected samples were blinded for group assignment by coding all animals by IDs. The collected biological samples were randomized by using random numbers and the group assignment was blinded during the data collection. Both mothers (during pregnancy) and infants were weighed every week. One day before sample collection, food was removed 30 min after the afternoon feeding, and biological samples were collected prior to the morning feeding. To collect biological samples, animals were anesthetized using 5–30 mg/kg ketamine or 5–8 mg/kg telazol. Both maternal and infant blood was collected using 5 mL lavender top (EDTA) tubes (Monoject, Cardinal Health, Dublin, OH, USA) and urine was collected from the bladder by ultrasound-guided transabdominal cystotomy using a 22-gauge needle and stored in a 15 mL Falcon tube. A placental sample was collected at GD150 transabdominally under ultrasound guidance using an 18-gauge needle attached to a sterile syringe. Sample processing was as previously described in (Hasegawa et al., 2022). Necropsy was conducted between 9:30 am–1:30 pm. First, infants at the age of PD180 were fasted and anesthetized with ketamine, and plasma and urine were collected. Then, euthanasia was performed with 120 mg/kg pentobarbital, followed by heparin injection, clamping of the descending aorta, and flushing with saline until clear. The kidney and brain (amygdala, hippocampus, hypothalamus, and prefrontal cortex) were collected, weighed, and immediately frozen on dry ice or liquid nitrogen to store at -80 °C until further analyses. Metabolite extraction and analysis by 1H NMR, and measurement of insulin, cholesterol, cytokine, and cortisol Detailed procedures were previously described (Hasegawa et al., 2022). Briefly, plasma and urine samples were filtered using Amicon Ultra Centrifugal Filter (3k molecular weight cutoff; Millipore, Billerica, MA, USA), and the supernatant was used for analysis. For both the placental and brain tissue samples, polar metabolites were extracted using our previously reported method (Hasegawa et al., 2020). A total of 180 μL of sample (tissue extract or filtered urine or serum) was transferred to 3 mm Bruker NMR tubes (Bruker, Billerica, MA, USA). Within 24 h of sample preparation, all 1H NMR spectra were acquired using the noesypr1d pulse sequence on a Bruker Avance 600 MHz NMR spectrometer (Bruker, Billerica, MA, USA) (O’Sullivan et al., 2013). Chenomx NMRSuite (version 8.1, Chenomx Inc., Edmonton, Canada) (Weljie et al., 2006) was used to identify and quantify metabolites. Heparin-treated plasma samples were used to measure insulin and 17 cytokines and chemokines (hs-CRP, Granulocyte-macrophage colony-stimulating factor, IFN-γ, TNF-α, transforming growth factor-α, monocyte chemoattractant protein-1, macrophage inflammatory protein-1β (MIP-1β), and interleukin (IL)-1β, IL-1 receptor antagonist (IL-1ra), IL-2, IL-6, IL-8, IL-10, IL-12/23 p40, IL-13, IL-15, and IL-17A) using a multiplex Bead-Based Kit (Millipore) on a Bio-Plex 100 (Bio-rad, Hercules, CA) following the manufacturer’s protocol. For each sample, a minimum of fifty beads per region were collected and analyzed with Bio-Plex Manager software using a 5-point standard curve with immune marker quantities extrapolated based on the standard curve. Two samples were removed for analysis of TNF-α and IL-1ra as technical errors (both from Animal ID 1132103: 895.2 and 1115.1 pg/mL at gestational days (GD) 90; 510.8 and 617.2 pg/mL at GD120, respectively). Plasma cholesterol level was measured by Clinical Laboratory Diagnostic Product (OSR6116) on Beckman Coulter AU480 (Beckman Coulter, Brea, CA). Infant plasma cortisol level at PD110 was assessed as previously described (Vandeleest et al., 2019; Walker et al., 2018). In short, infants were transferred to a test room at 9 am and blood was drawn at 11 am (Sample 1), followed by another blood collection at 4 pm (Sample 2) and intramuscular injection of 500 μg/kg dexamethasone (Dex) (American Regent Laboratories, Inc., Shirley, NY). On the next day, a blood sample was collected at 8:30 am (Sample 3), and then 2.5 IU of adrenocorticotropic hormone (Amphastar Pharmaceuticals, Inc., Rancho Cucamonga, CA) was injected intramuscularly. The last blood was collected (Sample 4) 30 min after adrenocorticotropic hormone injection. The collected blood samples were processed and stored, and cortisol concentration was assessed by a chemiluminescent assay on the ADVIA Centaur CP platform

This statistic depicts the average body weight of U.S. females aged 20 years and over from 1999 to 2016, by age. According to the data, the average female body weight for those aged 40-59 years was 169.4 in 1999-2000 and increased to 176.4 as of 2015-2016.

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Additional file 3: Table S2. Male and female weight-for-height mean and SD by centimeter from 50–140 cm in males and 50–134 cm in females.

IntroductionObesity is a global concern in dogs with an increasing prevalence, and effective weight loss solutions are required that work in different geographical regions. The main objective was to conduct an international, multi-centre, weight loss trial to determine the efficacy of a dietary weight loss intervention in obese pet dogs.MethodsA 3-month prospective observational cohort study of weight loss in 926 overweight dogs was conducted at 340 veterinary practices in 27 countries. Commercially available dry or wet weight loss diets were used, with the initial energy allocation being 250–335 kJ/kg target body weight0.75/day (60–80 kcal/kg target body weight0.75/day) depending on sex and neuter status. The primary outcome measure was percentage weight loss; the main secondary outcomes were changes in activity, quality of life, and food-seeking behaviour, which were subjectively determined from owner descriptions.ResultsAt baseline, median (range) age was 74 (12 to 193) months and median body condition score was 8 (range 7–9). 896 of the 926 dogs (97%) lost weight, with mean weight loss being 11.4 ±5.84%. Sexually intact dogs lost more weight than neutered dogs (P = 0.001), whilst female dogs lost more weight than male dogs (P = 0.007), with the difference being more pronounced in North and South American dogs (median [Q1, Q3]: female: 11.5% [8.5%, 14.5%]; male: 9.1% [6.3%, 12.1%], P = 0.053) compared with those from Europe (female: 12.3% [8.9%, 14.9%]; male: 10.9% [8.6%, 15.4%]). Finally, subjective scores for activity (P

IntroductionFeline obesity is a worldwide concern which has recently been formally classified as a disease by the veterinary community. Management involves invoking controlled weight loss by feeding a purpose-formulated food in restricted quantities and altering physical activity. Most weight loss studies conducted in cats have been undertaken in research cat colonies from single geographic locations. The aim of this multi-centre cohort study was to determine the efficacy of a short-term dietary weight loss intervention in overweight pet cats across a range of geographical locations globally.Materials and methodsA 3-month (median 13 weeks, inter-quartile range [IQR] 12–15 weeks) weight loss programme was conducted at 188 veterinary practices in 22 countries, and involving 730 cats, 413 of which completed the programme and had complete data available. All were fed commercially available dry or wet weight loss diets, and median energy intake was 53 kcal/kg BW0.711/day. The Royal Canin Ethics Committee approved the study, and owners gave informed consent. Owners completed behavioural questionnaires assessing begging, physical activity and quality of life (QOL). Linear mixed models were used to assess the respective influence of time, age, and initial body condition score (BCS) on weight loss and behavioural observations.ResultsAt baseline, median age was 72 months (range 12–200 months) and median BCS was 8 (range 7–9). In all, 402/413 cats (97%) lost weight (mean 10.6±6.3%) during the programme at a rate of 0.8 ±0.50%/week. Based upon owner questionnaires, activity and QOL improved (both P

ImportanceThe PAWPER tape system is one of the three most accurate paediatric weight estimation systems in the world. The latest version of the tape, which does not rely on a subjective assessment of habitus, is the PAWPER XL-MAC method which uses length and mid-arm circumference (MAC) to estimate weight. It was derived and validated in a population in the USA and has not yet been fully validated in a population from a resource-limited setting.ObjectiveThe objective of this study was to evaluate the performance of the PAWPER XL-MAC tape weight estimation system in a large dataset sample of children from resource-limited settings.MethodsThis was a “virtual” study in which weight estimates were generated using the PAWPER XL-MAC tape and Broselow tape 2007B and 2011A editions in a very large open access dataset. The dataset contained anthropometric information of children aged 6 to 59 months from standardised nutritional surveys in 51 low- and middle-income countries. The performance of PAWPER XL-MAC method was compared with the Broselow tape and a new length- and habitus-based tape, the Ralston method.Main outcomes and measuresThe bias of the weight estimation methods was assessed using the mean percentage error (MPE) and precision using the 95% limits of agreement (LOA) of the MPE. The overall accuracy was denoted by the percentage of weight estimates falling within 10% and 20% of actual weight (abbreviated as p10 and p20 respectively).ResultsThe MPE (LOA) for the PAWPER XL-MAC tape, the Broselow 2007B and 2011A and Ralston method were 1.9 (-15.3, 19.2), 5.4 (-15.9, 26.7), 7.7 (-13.3, 30.5) and -0.7 (-20.2, 19.3) respectively. The p10 and p20 for each method were 79.3% and 96.9% for the PAWPER XL-MAC tape, 64.3% and 91.0% for the Broselow tape 2007B, 55.5% and 85.9% for the Broselow tape 2011A and 67.4 and 94.0% for the Ralston method respectively. The PAWPER XL-MAC system was statistically significantly more accurate than the Broselow tape 2011A, the Broselow tape 2007B and the Ralston method. The relative difference in accuracy (p10) was 43% (odds ratio 4.4 (4.4, 4.5), p

The effects of age (9 months old), high-fat diet (4.5 months old), and the loss of the xeno- and endobiotic metabolizing enzymes Cyp2b9, Cyp2b10, and Cyp2b13 (Cyp2b-null mice) on the male murine hepatic lipidome was compared. Hierarchical clustering and principal component analysis show that age perturbs phospholipid profiles and serum lipid markers the most compared to healthy, young mice; followed by a high-fat diet and then loss of Cyp2b. Lipid profiles from older mice followed by diet-induced obese mice contain greater n-6 fatty acids than normal diet (ND)-fed young mice that contain significantly more n-3 fatty acids. The lack of Cyp2b typically enhanced the adverse effects found in the older (9 mo) mice with increased liver injury, cluster of phospholipids, and weight gain combined with a deteriorating cholesterol profile.

Treatment of experimental groups Animal care procedures were approved by Clemson University’s Institutional Animal Care and Use committee. Cyp2b-null mice were developed using CRISPR/Cas9 as previously described (Kumar, et al., 2017) and wildtype (WT) B6 mice were purchased from The Jackson Laboratory (Bar Harbor, ME, USA) at 3 weeks of age and acclimated for 6 weeks prior to treatment. WT and Cyp2b-null male (9 weeks old) mice were divided into groups (n=9) and fed either commercially available diets; either a normal chow diet (ND; 2018S-Envigo Teklad Diet, 3.1 Kcal/g: 18.6% protein, 6.2 % fat, 44.2% carbohydrates; Madison, WI USA) or a high-fat diet (HFD; Envigo TD.06414, 5.1 Kcal/g: 60.3% fat (36% saturated, 41% monounsaturated, 23% polyunsaturated fat), 18.3% protein, 21.4% carbohydrates; Madison, WI USA)(Table 1) for 10 weeks (Heintz, et al., 2019). Mice were 4.5 months old at the end of the HFD study and referred to as ND-fed young or HFD-fed young; WT or Cyp2b-null mice. An additional experimental group of WT (Jackson) and Cyp2b-null male mice (n= 5) were fed a ND until they reached 9 months (termed old WT and old Cyp2b-null mice). At the end of the studies, mice were weighed, anesthetized, and blood collected by heart puncture prior to euthanasia and serum prepared. Serum biomarkers and liver triglycerides (TAG) were measured as described (Heintz, et al., 2019). Liver and inguinal white adipose tissue (WAT) were excised, weighed, and divided by total body weight to determine the hepatosomatic index (HSI) and white adipose somatic index (WSI). Tissues were immediately snap frozen in liquid nitrogen and stored at -80°C.

Mass Spectrometry Lipids were extracted and mass spectrometry performed using a Sciex AC LC system and Sciex QTrap5500 mass spectrometer (Framingham, MA, USA). Phospholipid species were identified and quantified from the livers of mice (n=3 for young (4.5 mo) ND and HFD-fed mice; n=5 for old (9 mo.) mice) from each experimental group by LC-MS/MS at the Emory Integrated Lipidomics Core (EILC) as described in their online protocols.

Estimated mean and 95% confidence intervals of latent growth parameters a.