Number of bcmca tourism and recreation features that were used in the Marxan analysis taht are found in each 2 km x 2 km planning unit.

This dataset illustrates the density of marine vessel traffic (by hours) within 5 km by 5 km grid cells for Canada's Pacific waters for 2010. Traffic is broken down into categories: Fishing, Government, Merchant, Passenger & Cruise, Pleasure & Yachts, Research, Tanker, and Tug & Service

The purpose of this dataset is to identify priority eelgrass habitat to help inform the marine feature identified at the BCMCA Marine Plants workshop. The British Columbia Marine Conservation Analysis (BCMCA) is a collaborative project assembling and analyzing spatial information about Canada's Pacific Ocean. The overall goal of the BCMCA is to identify marine areas of high conservation value and marine areas important to human use. Results of the project are intended to inform and help advance marine planning initiatives in BC by providing collaborative, peer-reviewed scientific analyses based on the best ecological and socio-economic spatial data at scales relevant to a BC coast-wide analysis. Data Source - British Columbia Marine Conservation Analysis. For more information on this dataset go to: soggy.zoology.ubc.ca:8080/geonetwork/srv/eng/catalog.search;jsessionid=node0l5m7s2c2z02q1dm4i2wwb3qw3331.node0?node=srv#/metadata/fafc8f11-bf21-4f2d-bea0-8a90029ce9ff

Explore the historical Whois records related to bcmca.net (Domain). Get insights into ownership history and changes over time.

Areal extents of Giant Kelp (Macrocystis intergrifolia)

Combined areas of interest or promise for wave energy development along the coast of BC.

Explore historical ownership and registration records by performing a reverse Whois lookup for the email address bcmca.net@contactprivacy.com..

Courants de marée est une couche raster dans laquelle chaque pixel représente la vitesse moyenne quadratique moyenne quadratique (RMS) des marées (m/s) sur un grand nombre de cycles de marée. Résolution raster 500 x 500 m. Données de 2008. Les données originales ont été fournies par la BCMCA et projetées à BC Albers - reprojetées pour une utilisation en ligne dans WGS84 Web Mercator Auxiliary Sphere par Keith Holmes. Plus d'informations sur les données originales et le modèle utilisés dans Foreman et al, 2000.

Le but de cet ensemble de données est d'identifier les vitesses de marée RMS dans la ZEE du Canadien Pacifique afin d'aider à éclairer la caractéristique physique identifiée dans le rapport physique de la BCMCA. Données présentées sous forme d'unités de planification de 2 km x 2 km pour l'analyse MARXAN.

Valeur quadratique moyenne quadratique (RMS) des vitesses des marées. La vitesse de marée RMS est issue d'un modèle de circulation diagnostique tridimensionnel pour le nord-est de l'océan Pacifique (Dr Mike Foreman, ministère des Pêches et des Océans). Les vitesses des marées modélisées sont barotropes, ce qui signifie que la densité n'est pas prise en compte. Les points extraits de ce modèle ont été affichés puis convertis en raster.

Fichier de métadonnées : http://bcmca.ca/datafiles/individualfiles/bcmca_eco_physical_hightidalcurrent_marxan_metadata.htm

Dr Mike Foreman (MPO)/The British Columbia Marine Conservation Analysis (BCMCA), un projet d'initiatives de Tides Canada

Date de publication : 2008

La British Columbia Marine Conservation Analysis (BCMCA) est un projet collaboratif rassemblant et analysant des informations spatiales sur l'océan Pacifique du Canada. L'objectif global de la BCMCA est d'identifier les zones marines à haute valeur de conservation et les zones marines importantes pour l'usage humain. Les résultats du projet visent à informer et à aider à faire progresser les initiatives de planification marine en Colombie-Britannique en fournissant des analyses scientifiques collaboratives et évaluées par des pairs fondées sur les meilleures données spatiales écologiques et d'utilisation humaine à des échelles pertinentes pour une analyse de l'ensemble de la côte de la Colombie-Britannique.

Foreman, M.G.G., W.R. Crawford, J.Y. Cherniawsky, R.F. Henry et M.R. Tarbotton. Un modèle de marée assimilateur à haute résolution pour le nord-est de l'océan Pacifique. Journal of Geophysical Research. 2000. Pages 105 : 28, 629 à 628, 652.

Aucune valeur de données : -3,40282306074e+038

Jeu de données créé par : Dr Mike Foreman (MPO)/The British Columbia Marine Conservation Analysis (BCMCA), un projet d'initiatives de Tides Canada - Foreman, M.G.G., W.R. Crawford, J.Y. Cherniawsky, R.F. Henry et M.R. Tarbotton. Un modèle de marée assimilateur à haute résolution pour le nord-est de l'océan Pacifique. Journal of Geophysical Research. 2000. Pages 105:28, 629-28, 652., et l'Institut Hakai.

The BCMA targeted therapies market to be worth $1.9 billion by 2030, representing a CAGR of 98% during the forecast period.

The British Columbia Marine Conservation Analysis (BCMCA) is a collaborative project assembling and analyzing spatial information about Canada's Pacific Ocean. The overall goal of the BCMCA is to identify marine areas of high conservation value and marine areas important to human use. Results of the project are intended to inform and help advance marine planning initiatives in BC by providing collaborative, peer-reviewed scientific analyses based on the best ecological and socio-economic spatial data at scales relevant to a BC coast-wide analysis.

Members of this family, which are predominantly found in the tumour necrosis factor receptor superfamily member 17, BCMA, are required for binding to tumour necrosis factor ligand TALL-1 .

IntroductionThe emergence of chimeric antigen receptor (CAR)-T therapy targeting B cell maturation antigen (BCMA) has improved the prognosis of patients with multiple myeloma (MM); however, the majority of patients eventually experience relapse.MethodsIn this study, employing the latest single-cell RNA sequencing technology, we examined 24 bone marrow or peripheral blood samples collected throughout the course of anti-BCMA CAR-T therapy, analyzing a total of 59,725 bone marrow cells and 72,479 peripheral blood cells.ResultsOur findings reveal that tumor cells in relapsed patient exhibit higher expression levels of HSP90B1 and HSPA5, and demonstrate significantly enriched pathways regarding endoplasmic reticulum stress and unfolded protein response. In the analysis of T cells, we observed that patient with impaired effector function and increased expression of immune checkpoints in endogenous T cell are more susceptible to relapse. Notably, T cells from both the bone marrow microenvironment and peripheral blood share highly similar biological characteristics.DiscussionOverall, this study provides a comprehensive atlas of endogenous immune cells, particularly in the relatively long term, after CAR-T therapy. It offers clinical evidence for a deeper understanding of the internal environment post CAR-T treatment and for identifying mechanisms underlying relapse.

Global B-Cell Maturation Antigen (BCMA) Targeted Therapies market size is expected to reach $36.66 billion by 2029 at 24.6%, rising incidence of multiple myeloma

Number of bcmca marine mammal features used in the Marxan analysis that are found in each 2 km x 2 km planning unit.

IntroductionThe emergence of chimeric antigen receptor (CAR)-T therapy targeting B cell maturation antigen (BCMA) has improved the prognosis of patients with multiple myeloma (MM); however, the majority of patients eventually experience relapse.MethodsIn this study, employing the latest single-cell RNA sequencing technology, we examined 24 bone marrow or peripheral blood samples collected throughout the course of anti-BCMA CAR-T therapy, analyzing a total of 59,725 bone marrow cells and 72,479 peripheral blood cells.ResultsOur findings reveal that tumor cells in relapsed patient exhibit higher expression levels of HSP90B1 and HSPA5, and demonstrate significantly enriched pathways regarding endoplasmic reticulum stress and unfolded protein response. In the analysis of T cells, we observed that patient with impaired effector function and increased expression of immune checkpoints in endogenous T cell are more susceptible to relapse. Notably, T cells from both the bone marrow microenvironment and peripheral blood share highly similar biological characteristics.DiscussionOverall, this study provides a comprehensive atlas of endogenous immune cells, particularly in the relatively long term, after CAR-T therapy. It offers clinical evidence for a deeper understanding of the internal environment post CAR-T treatment and for identifying mechanisms underlying relapse.

Number of BCMCA plant features used in the Marxan analysis that are found in each 2 km x 2 km planning unit.

Number of bcmca physical features used in the Marxan analysis that are found in each 2 km x 2 km planning unit.

Number of bcmca marine fish and invertebrate features used in the Marxan analysis that are found in each 2km x 2 km planning unit.

Number of bcmca features used in the Marxan analysis that are found in each 2 km x 2 km planning unit.

Observations of an algal species Lithothrix aspergillum (red algae) considered rare in BC, 2008.