Fragility Multi-Center Retrospective Study

iEEG and EEG data from 5 centers is organized in our study with a total of 100 subjects. We publish 4 centers' dataset here due to data sharing issues.

Acquisitions include ECoG and SEEG. Each run specifies a different snapshot of EEG data from that specific subject's session. For seizure sessions, this means that each run is a EEG snapshot around a different seizure event.

For additional clinical metadata about each subject, refer to the clinical Excel table in the publication.

Data Availability

NIH, JHH, UMMC, and UMF agreed to share. Cleveland Clinic did not, so requires an additional DUA.

All data, except for Cleveland Clinic was approved by their centers to be de-identified and shared. All data in this dataset have no PHI, or other identifiers associated with patient. In order to access Cleveland Clinic data, please forward all requests to Amber Sours, SOURSA@ccf.org:

Amber Sours, MPH Research Supervisor | Epilepsy Center Cleveland Clinic | 9500 Euclid Ave. S3-399 | Cleveland, OH 44195 (216) 444-8638

You will need to sign a data use agreement (DUA).

Sourcedata

For each subject, there was a raw EDF file, which was converted into the BrainVision format with mne_bids. Each subject with SEEG implantation, also has an Excel table, called electrode_layout.xlsx, which outlines where the clinicians marked each electrode anatomically. Note that there is no rigorous atlas applied, so the main points of interest are: WM, GM, VENTRICLE, CSF, and OUT, which represent white-matter, gray-matter, ventricle, cerebrospinal fluid and outside the brain. WM, Ventricle, CSF and OUT were removed channels from further analysis. These were labeled in the corresponding BIDS channels.tsv sidecar file as status=bad. The dataset uploaded to openneuro.org does not contain the sourcedata since there was an extra anonymization step that occurred when fully converting to BIDS.

Derivatives

Derivatives include: * fragility analysis * frequency analysis * graph metrics analysis * figures

These can be computed by following the following paper: Neural Fragility as an EEG Marker for the Seizure Onset Zone

Events and Descriptions

Within each EDF file, there contain event markers that are annotated by clinicians, which may inform you of specific clinical events that are occuring in time, or of when they saw seizures onset and offset (clinical and electrographic).

During a seizure event, specifically event markers may follow this time course:

* eeg onset, or clinical onset - the onset of a seizure that is either marked electrographically, or by clinical behavior. Note that the clinical onset may not always be present, since some seizures manifest without clinical behavioral changes.
* Marker/Mark On - these are usually annotations within some cases, where a health practitioner injects a chemical marker for use in ICTAL SPECT imaging after a seizure occurs. This is commonly done to see which portions of the brain are active metabolically.
* Marker/Mark Off - This is when the ICTAL SPECT stops imaging.
* eeg offset, or clinical offset - this is the offset of the seizure, as determined either electrographically, or by clinical symptoms.

Other events included may be beneficial for you to understand the time-course of each seizure. Note that ICTAL SPECT occurs in all Cleveland Clinic data. Note that seizure markers are not consistent in their description naming, so one might encode some specific regular-expression rules to consistently capture seizure onset/offset markers across all dataset. In the case of UMMC data, all onset and offset markers were provided by the clinicians on an Excel sheet instead of via the EDF file. So we went in and added the annotations manually to each EDF file.

Seizure Electrographic and Clinical Onset Annotations

For various datasets, there are seizures present within the dataset. Generally there is only one seizure per EDF file. When seizures are present, they are marked electrographically (and clinically if present) via standard approaches in the epilepsy clinical workflow.

Clinical onset are just manifestation of the seizures with clinical syndromes. Sometimes the maker may not be present.

Seizure Onset Zone Annotations

What is actually important in the evaluation of datasets is the clinical annotations of their localization hypotheses of the seizure onset zone.

These generally include:

* early onset: the earliest onset electrodes participating in the seizure that clinicians saw
* early/late spread (optional): the electrodes that showed epileptic spread activity after seizure onset. Not all seizures has spread contacts annotated.

Surgical Zone (Resection or Ablation) Annotations

For patients with the post-surgical MRI available, then the segmentation process outlined above tells us which electrodes were within the surgical removed brain region.

Otherwise, clinicians give us their best estimate, of which electrodes were resected/ablated based on their surgical notes.

For surgical patients whose postoperative medical records did not explicitly indicate specific resected or ablated contacts, manual visual inspection was performed to determine the approximate contacts that were located in later resected/ablated tissue. Postoperative T1 MRI scans were compared against post-SEEG implantation CT scans or CURRY coregistrations of preoperative MRI/post SEEG CT scans. Contacts of interest in and around the area of the reported resection were selected individually and the corresponding slice was navigated to on the CT scan or CURRY coregistration. After identifying landmarks of that slice (e.g. skull shape, skull features, shape of prominent brain structures like the ventricles, central sulcus, superior temporal gyrus, etc.), the location of a given contact in relation to these landmarks, and the location of the slice along the axial plane, the corresponding slice in the postoperative MRI scan was navigated to. The resected tissue within the slice was then visually inspected and compared against the distinct landmarks identified in the CT scans, if brain tissue was not present in the corresponding location of the contact, then the contact was marked as resected/ablated. This process was repeated for each contact of interest.

References

Adam Li, Chester Huynh, Zachary Fitzgerald, Iahn Cajigas, Damian Brusko, Jonathan Jagid, Angel Claudio, Andres Kanner, Jennifer Hopp, Stephanie Chen, Jennifer Haagensen, Emily Johnson, William Anderson, Nathan Crone, Sara Inati, Kareem Zaghloul, Juan Bulacio, Jorge Gonzalez-Martinez, Sridevi V. Sarma. Neural Fragility as an EEG Marker of the Seizure Onset Zone. bioRxiv 862797; doi: https://doi.org/10.1101/862797

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896). https://doi.org/10.21105/joss.01896

Holdgraf, C., Appelhoff, S., Bickel, S., Bouchard, K., D'Ambrosio, S., David, O., … Hermes, D. (2019). iEEG-BIDS, extending the Brain Imaging Data Structure specification to human intracranial electrophysiology. Scientific Data, 6, 102. https://doi.org/10.1038/s41597-019-0105-7

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8

———————————————————————————————— ORIGINAL PAPERS ———————————————————————————————— Mano, Marsel, Anatole Lécuyer, Elise Bannier, Lorraine Perronnet, Saman Noorzadeh, and Christian Barillot. 2017. “How to Build a Hybrid Neurofeedback Platform Combining EEG and FMRI.” Frontiers in Neuroscience 11 (140). https://doi.org/10.3389/fnins.2017.00140 Perronnet, Lorraine, L Anatole, Marsel Mano, Maureen Clerc, Fabien Lotte, and Christian Barillot. 2018. “Learning 2-in-1 : Towards Integrated EEG-FMRI-Neurofeedback.” BioRxiv, no. 397729. https://doi.org/10.1101/397729.

———————————————————————————————— OVERVIEW ———————————————————————————————— This dataset XP2 can be pull together with the dataset XP1 (DOI: 10.18112/openneuro.ds002336.v1.0.0). Data acquisition methods have been described in Perronnet et al. (2017, Frontiers in Human Neuroscience). Simultaneous 64 channel EEG and fMRI during right-hand motor imagery and neurofeedback (NF) were acquired in this study (as well as in XP1). This study involved 16 subjects randomly assigned to two groups: in a first group they performed bimodal EEG-fMRI NF with a bi-dimensional feedback metaphor, in the second group the same task was executed with a mono-dimensional feedback.

———————————————————————————————— EXPERIMENTAL PARADIGM ————————————————————————————————

The experimental protocol consisted of 5 EEG-fMRI runs with a 20s block design alternating rest and task. 1 block = 20s rest + 20s task. Task description : _task-MIpre : motor imagery run without NF. 8 blocks. _task-1dNF or _task-2dNF : bimodal neurofeedback, with either a mono-dimensional neurofeedback display (mean of EEG NF and fMRI NF scores), either a bi-dimensional display (one modality per dimension). The list of subjects with 1d or 2d is given above. Each subjects had 3 runs. 8 blocks per run. _task-MIpost : motor imagery run without NF. 8 blocks. Subjects with mono-dimensional feedback display : xp201 : 1D xp202 : 1D xp203 : 1D xp206 : 1D xp211 : 1D xp218 : 1D xp219 : 1D xp220 : 1D xp222 : 1D

Subjects with bi-dimensional feedback display : xp204 : 2D xp205 : 2D xp207 : 2D xp213 : 2D xp216 : 2D xp217 : 2D xp221 : 2D

———————————————————————————————— EEG DATA ———————————————————————————————— EEG data was recorded using a 64-channel MR compatible solution from Brain Products (Brain Products GmbH, Gilching, Germany).

RAW EEG DATA

EEG was sampled at 5kHz with FCz as the reference electrode and AFz as the ground electrode, and a resolution of 0.5 microV. Following the BIDs arborescence, raw eeg data for each task can be found for each subject in

XP2/sub-xp2*/eeg

in Brain Vision Recorder format (File Version 1.0). Each raw EEG recording includes three files: the data file (.eeg), the header file (.vhdr) and the marker file (*.vmrk). The header file contains information about acquisition parameters and amplifier setup. For each electrode, the impedance at the beginning of the recording is also specified. For all subjects, channel 32 is the ECG channel. The 63 other channels are EEG channels.

The marker file contains the list of markers assigned to the EEG recordings and their properties (marker type, marker ID and position in data points). Three type of markers are relevant for the EEG processing: R128 (Response): is the fMRI volume marker to correct for the gradient artifact S 99 (Stimulus): is the protocol marker indicating the start of the Rest block S 2 (Stimulus): is the protocol marker indicating the start of the Task (Motor Execution Motor Imagery or Neurofeedback)
Warning : in few EEG data, the first S99 marker might be missing, but can be easily “added” 20 s before the first S 2.

PREPROCESSED EEG DATA

Following the BIDs arborescence, processed eeg data for each task can be found for each subject in

XP2/derivatives/sub-xp2*/eeg_pp/*eeg_pp.*

and following the Brain Analyzer format. Each processed EEG recording includes three files: the data file (.dat), the header file (.vhdr) and the marker file (*.vmrk), containing information similar to those described for raw data. In the header file of preprocessed data channels location are also specified. In the marker file the location in data points of the identified heart pulse (R marker) are specified as well.

EEG data were pre-processed using BrainVision Analyzer II Software, with the following steps: Automatic gradient artifact correction using the artifact template subtraction method (Sliding average calculation with 21 intervals for sliding average and all channels enabled for correction. Downsampling with factor: 25 (200 Hz) Low Pass FIR Filter:Cut-off Frequency: 50 Hz. Ballistocardiogram (pulse) artifact correction using a semiautomatic procedure (Pulse Template searched between 40 s and 240 s in the ECG channel with the following parameters:Coherence Trigger = 0.5, Minimal Amplitude = 0.5, Maximal Amplitude = 1.3). A Pulse Artifact marker R was associated to each identified pulse. Segmentation relative to the first block marker (S 99) for all the length of the training protocol (las S 2 + 20 s).

EEG-NF SCORES

Neurofeedback scores can be found in the .mat structures in

XP2/derivatives/sub-xp2*/NF_eeg/d_sub*NFeeg_scores.mat

Structures names NF_eeg are composed by the following subfields: ID : Subject ID, for example sub-xp201 lapC3_ERD : a 1x1280 vector of neurofeedback scores. 4 scores per secondes, for the whole session. eeg : a 64x80200 matrix, with the pre-processed EEG signals with the step described above, filtered between 8 and 30 Hz. lapC3_bandpower_8Hz_30Hz : 1x1280 vector. Bandpower of the filtered signal with a laplacian centred on C3, used to estimate the lapC3_ERD. lapC3_filter : 1x64 vector. Laplacian filter centred above C3 channel. ———————————————————————————————— BOLD fMRI DATA ———————————————————————————————— All DICOM files were converted to Nifti-1 and then in BIDs format (version 2.1.4) using the software dcm2niix (version v1.0.20190720 GVV7.4.0)

fMRI acquisitions were performed using echo- planar imaging (EPI) and covered the superior half of the brain with the following parameters 3T Siemens Verio EPI sequence TR=1 s TE=23 ms Resolution 2x2x4 mm N of slices: 16 No slice gap

As specified in the relative task event files in XP2\ *events.tsv files onset, the scanner began the EPI pulse sequence two seconds prior to the start of the protocol (first rest block), so the the first two TRs should be discarded.

The useful TRs for the runs are therefore

-task-MIpre and task-MIpost: 320 s (2 to 302) -task-1dNF and task-2dNF: 320 s (2 to 302)

In task events files for the different tasks, each column represents:

• 'onset': onset time (sec) of an event
• 'duration': duration (sec) of the event
• 'trial_type': trial (block) type: rest or task (Rest, Task-MI, Task-NF)
• 'stim_file': image presented in a stimulus block. During Rest or Motor Imagery (Task-MI) instructions were presented to the subject. On the other hand, during Neurofeedback blocks (Task-NF) the image presented was a ball moving in a square for the bidimensional NF (task-2dNF) or a ball moving along a gauge for the unidimensional NF (task-1dNF) that the subject could control self-regulating his EEG and fMRI brain activity.

Following the BIDs arborescence, the functional data and relative metadata are found for each subject in the following directory

XP2/sub-xp2*/func

BOLD-NF SCORES

For each subject and NF session, a matlab structure with BOLD-NF features can be found in

XP2/derivatives/sub-xp2*/NF_bold/

In view of BOLD-NF scores computation, fMRI data were preprocessed using AutoMRI, a software based on spm8 and with the following steps: slice-time correction, spatial realignment and coregistration with the anatomical scan, spatial smoothing with a 8 mm Gaussian kernel and normalization to the Montreal Neurological Institute template For each session, a first level general linear model analysis modeling was then performed. The resulting activation maps (voxel-wise Family-Wise error corrected at p < 0.05) were used to define two ROIs (9x9x3 voxels) around the maximum of activation in the ipsilesional primary motor area (M1) and supplementary motor area (SMA) respectively.

The BOLD-NF scores were calculated as the difference between percentage signal change in the two ROIs (SMA and M1) and a large deep background region (slice 3 out of 16) whose activity is not correlated with the NF task. A smoothed version of the NF scores over the precedent three volumes was also computed.

The NF_boldi structure has the following structure

NF_bold → .m1→ .nf → .smoothnf
→ .roimean (averaged BOLD signal in the ROI) → .bgmean (averaged BOLD signal in the background slice) → .method
NFscores.fmri → .sma→ .nf → .smoothnf
→ .roimean (averaged BOLD signal in the ROI) → .bgmean (averaged BOLD signal in the background slice) → .method

Where the subfield method contains information about the ROI size (.roisize), the background mask (.bgmask) and ROI mask (.roimask).

More details about signal

Supporting materials for the GX Dataset.

The GX Dataset is a dataset of combined tES, EEG, physiological, and behavioral signals from human subjects.

Publication

A full data descriptor is published in Nature Scientific Data. Please cite this work as:

Gebodh, N., Esmaeilpour, Z., Datta, A. et al. Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation. Sci Data 8, 274 (2021). https://doi.org/10.1038/s41597-021-01046-y

Descriptions

A dataset combining high-density electroencephalography (EEG) with physiological and continuous behavioral metrics during transcranial electrical stimulation (tES; including tDCS and tACS). Data includes within subject application of nine High-Definition tES (HD-tES) types targeted three brain regions (frontal, motor, parietal) with three waveforms (DC, 5Hz, 30Hz), with more than 783 total stimulation trials over 62 sessions with EEG, physiological (ECG or EKG, EOG), and continuous behavioral vigilance/alertness metrics (CTT task).

Acknowledgments

Portions of this study were funded by X (formerly Google X), the Moonshot Factory. The funding source had no influence on study conduction or result evaluation. MB is further supported by grants from the National Institutes of Health: R01NS101362, R01NS095123, R01NS112996, R01MH111896, R01MH109289, and (to NG) NIH-G-RISE T32GM136499.

We would like to thank Yuxin Xu and Michaela Chum for all their technical assistance.

Extras

For downsampled data (1 kHz ) please see (in .mat format):

• Experiment 1 : https://doi.org/10.5281/zenodo.8401160
• Experiment 2 : https://doi.org/10.5281/zenodo.3840617

Code used to import, process, and plot this dataset can be found here:

• GitHub : https://github.com/ngebodh/GX_tES_EEG_Physio_Behavior

Additional figures for this project have been shared on Figshare. Trial-wise figures can be found here:

• PSD: https://doi.org/10.6084/m9.figshare.14810517.v1
• Topoplots During Stimulation: https://doi.org/10.6084/m9.figshare.14810478
• Voltage timeseries, spectrogram and behavior: https://doi.org/10.6084/m9.figshare.14810442.v1

The full dataset is also provided in BIDS format here:

• Data in BIDS format: https://doi.org/10.18112/openneuro.ds003670.v1.1.0

Data License
Creative Common 4.0 with attribution (CC BY 4.0)

NOTE

Please email ngebodh01@citymail.cuny.edu with any questions.

Follow @NigelGebodh for latest updates.

We present raw multimodal empirical data from a study with The Virtual Brain (TVB) based on this data. Structural and functional data have been prepared in accordance with Brain Imaging Data Structure (BIDS) standards and annotated according to the openMINDS metadata framework. This simultaneous electroencephalography (EEG) - functional magnetic resonance imaging (fMRI) resting-state data, diffusion-weighted MRI (dwMRI), and structural MRI were acquired for 50 healthy adult subjects (18 - 80 years of age, mean 41.12±18.20; 30 females, 20 males) at the Berlin Center for Advanced Imaging, Charité University Medicine, Berlin, Germany. We constructed personalized models from this multimodal data of 50 healthy individuals with TVB in a previous study (Triebkorn et al. 2024). We present this large comprehensive empirical dataset in an annotated and structured format following BIDS standards for EEG and MRI. We describe how we processed and converted the diverse data sources to make it reusable. In its current form, this dataset can be reused for further research and provides ready-to-use data for a large data set of healthy subjects with a wide age range.

Overview

This dataset contains raw and pre-processed EEG data from a mobile EEG study investigating the additive effects of task load, motor demand, and environmental complexity on attention. More details will be provided once the manuscript has passed peer-review.

All preprocessing and analysis code is deposited in the code directory. The entire MATLAB pipeline can be reproduced by executing the run_pipeline.m script. In order to run these scripts, you will need to ensure you have the required MATLAB toolboxes and R packages on your system. You will also need to adapt def_local.m to specify local paths to MATLAB and EEGLAB. Descriptive statistics and mixed-effects models can be reproduced in R by running the stat_analysis.R script.

See below for software details.

Citing this dataset

For more information, see the dataset_description.json file.

Format

Dataset is formatted according to the EEG-BIDS extension (Pernet et al., 2019) and the BIDS extension proposal for common electrophysiological derivatives (BEP021) v0.0.1, which can be found here:

https://docs.google.com/document/d/1PmcVs7vg7Th-cGC-UrX8rAhKUHIzOI-uIOh69_mvdlw/edit#heading=h.mqkmyp254xh6

Note that BEP021 is still a work in progress as of 2021-03-01.

Generally, you can find data in the .tsv files and descriptions in the accompanying .json files.

An important BIDS definition to consider is the "Inheritance Principle" (see 3.5 in the BIDS specification: http://bids.neuroimaging.io/bids_spec.pdf), which states:

Any metadata file (​.json​,​.bvec​,​.tsv​, etc.) may be defined at any directory level. The values from the top level are inherited by all lower levels unless they are overridden by a file at the lower level.

Details about the experiment

Forty-four healthy adults aged 18-40 performed an oddball task involving complex tone (piano and horn) stimuli in three settings: (1) sitting in a quiet room in the lab (LAB); (2) walking around a sports field (FIELD); (3) navigating a route through a university campus (CAMPUS).

Participants performed each environmental condition twice: once while attending to oddball stimuli (i.e. counting the number of presented deviant tones; COUNT), and once while disregarding or ignoring the tone stimuli (IGNORE).

EEG signals were recorded from 32 active electrodes using a Brain Vision LiveAmp 32 amplifier. See manuscript for further details.

MATLAB software details

MATLAB Version: 9.7.0.1319299 (R2019b) Update 5 MATLAB License Number: 678256 Operating System: Microsoft Windows 10 Enterprise Version 10.0 (Build 18363) Java Version: Java 1.8.0_202-b08 with Oracle Corporation Java HotSpot(TM) 64-Bit Server VM mixed mode

• MATLAB (v9.7)
• Simulink (v10.0)
• Curve Fitting Toolbox (v3.5.10)
• DSP System Toolbox (v9.9)
• Image Processing Toolbox (v11.0)
• MATLAB Compiler (v7.1)
• MATLAB Compiler SDK (v6.7)
• Parallel Computing Toolbox (v7.1)
• Signal Processing Toolbox (v8.3)
• Statistics and Machine Learning Toolbox (v11.6)
• Symbolic Math Toolbox (v8.4)
• Wavelet Toolbox (v5.3)

The following toolboxes/helper functions were also used:

• EEGLAB (v2019.1)
• ERPLAB (v8.02)
• ICLabel (v1.3)
• clean_rawdata (v2.3)
• bids-matlab-tools (v5.2)
• dipfit (v3.4)
• firfilt (v2.4)
• export_fig (v3.12)
• ColorBrewer (v3.1.0)

R software details

R version 3.6.2 (2019-12-12)

Platform: x86_64-w64-mingw32/x64 (64-bit)

locale: _LC_COLLATE=English_Australia.1252_, _LC_CTYPE=English_Australia.1252_, _LC_MONETARY=English_Australia.1252_, _LC_NUMERIC=C_ and _LC_TIME=English_Australia.1252_

attached base packages:

• stats
• graphics
• grDevices
• utils
• datasets
• methods
• base

other attached packages:

• sjPlot(v.2.8.7)
• emmeans(v.1.5.1)
• car(v.3.0-10)
• carData(v.3.0-4)
• lme4(v.1.1-23)
• Matrix(v.1.2-18)
• data.table(v.1.13.0)
• forcats(v.0.5.0)
• stringr(v.1.4.0)
• dplyr(v.1.0.2)
• purrr(v.0.3.4)
• readr(v.1.4.0)
• tidyr(v.1.1.2)
• tibble(v.3.0.4)
• ggplot2(v.3.3.2)
• tidyverse(v.1.3.0)

loaded via a namespace (and not attached):

• nlme(v.3.1-149)
• pbkrtest(v.0.4-8.6)
• fs(v.1.5.0)
• lubridate(v.1.7.9)
• insight(v.0.12.0)
• httr(v.1.4.2)
• numDeriv(v.2016.8-1.1)
• tools(v.3.6.2)
• backports(v.1.1.10)
• utf8(v.1.1.4)
• R6(v.2.4.1)
• sjlabelled(v.1.1.7)
• DBI(v.1.1.0)
• colorspace(v.1.4-1)
• withr(v.2.3.0)
• tidyselect(v.1.1.0)
• curl(v.4.3)
• compiler(v.3.6.2)
• performance(v.0.5.0)
• cli(v.2.1.0)
• rvest(v.0.3.6)
• xml2(v.1.3.2)
• sandwich(v.3.0-0)
• labeling(v.0.3)
• bayestestR(v.0.7.2)
• scales(v.1.1.1)
• mvtnorm(v.1.1-1)
• digest(v.0.6.25)
• foreign(v.0.8-76)
• minqa(v.1.2.4)
• rio(v.0.5.16)
• pkgconfig(v.2.0.3)
• dbplyr(v.1.4.4)
• rlang(v.0.4.8)
• readxl(v.1.3.1)
• rstudioapi(v.0.11)
• farver(v.2.0.3)
• generics(v.0.0.2)
• zoo(v.1.8-8)
• jsonlite(v.1.7.1)
• zip(v.2.1.1)
• magrittr(v.1.5)
• parameters(v.0.8.6)
• Rcpp(v.1.0.5)
• munsell(v.0.5.0)
• fansi(v.0.4.1)
• abind(v.1.4-5)
• lifecycle(v.0.2.0)
• stringi(v.1.4.6)
• multcomp(v.1.4-14)
• MASS(v.7.3-53)
• plyr(v.1.8.6)
• grid(v.3.6.2)
• blob(v.1.2.1)
• parallel(v.3.6.2)
• sjmisc(v.2.8.6)
• crayon(v.1.3.4)
• lattice(v.0.20-41)
• ggeffects(v.0.16.0)
• haven(v.2.3.1)
• splines(v.3.6.2)
• pander(v.0.6.3)
• sjstats(v.0.18.1)
• hms(v.0.5.3)
• knitr(v.1.30)
• pillar(v.1.4.6)
• boot(v.1.3-25)
• estimability(v.1.3)
• effectsize(v.0.3.3)
• codetools(v.0.2-16)
• reprex(v.0.3.0)
• glue(v.1.4.2)
• modelr(v.0.1.8)
• vctrs(v.0.3.4)
• nloptr(v.1.2.2.2)
• cellranger(v.1.1.0)
• gtable(v.0.3.0)
• assertthat(v.0.2.1)
• xfun(v.0.18)
• openxlsx(v.4.2.2)
• xtable(v.1.8-4)
• broom(v.0.7.1)
• coda(v.0.19-4)
• survival(v.3.2-7)
• lmerTest(v.3.1-3)
• statmod(v.1.4.34)
• TH.data(v.1.0-10)
• ellipsis(v.0.3.1)

This dataset was a part of the IJCAI 2023 competition : CC6: IntEr-HRI: Intrinsic Error Evaluation during Human-Robot Interaction (IJCAI'23 Official Website). This dataset repository is divided into 3 versions:

• Version 1: Training data + Metadata
• Version 2: Test data
• Version 3: Complete dataset (EEG + EMG)

For more detailed information about the competition, please visit our competition webpage.

This dataset contains recordings of the electroencephalogram (EEG) data from eight subjects who were assisted in moving their right arm by an active orthosis.

The orthosis-supported movements were elbow joint movements, i.e., flexion and extension of the right arm. While the orthosis was actively moving the subject's arm, some errors were deliberately introduced for a short duration of time. During this time, the orthosis moved in the opposite direction. The errors are very simple and easy to detect. EEG and EMG data are provided. The recorded EEG data follows the BrainVision Core Data Format 1.0, consisting of a binary data file (.eeg), a header file (.vhdr), and a marker file (.vmrk) (https://www.brainproducts.com/support-resources/brainvision-core-data-format-1-0/). For ease of use, the data can be exported into the widely adopted BIDS format. Furthermore, for data analysis, processing, and classification, two popular options are available - MNE (Python) and EEGLAB (MATLAB).

If you use our dataset, cite our paper.

Frontiers in Human Neuroscience DOI: 10.3389/fnhum.2024.1304311

BibTeX citation:

Brain-Computer Interfaces, and especially passive Brain-Computer Interfaces (pBCI), with their ability to estimate and detect mental states, are receiving increasing attention from both the scientific and the research and development communities. Many pBCIs aim to increase the safety of complex work environments such as in the aeronautical domain. Therefore, mental workload, vigilance and decision-making are some of the most commonly examined aspects of cognition within this field of research. A large proportion of pBCIs involve a component of machine learning and signal processing as the data that are collected need to be transformed into a reliable estimate of the users’ current mental state (e.g. mental workload). Improving this component is a major challenge for researchers, requiring large quantities of data. While data sharing is common for the active BCI community, open pBCI datasets are scarcer and generally incomplete with regards to the information they report. This is particularly true for datasets encompassing several tasks or sessions, which are of importance for tackling the challenges of transfer learning. Testing new pipelines, feature extraction algorithms and classifiers are central issues for future advances in research within this domain, as well as for algorithm benchmark and research reproducibility.The COG-BCI database presented here is comprised of the recordings of 29 participants over 3 individual sessions with 4 different tasks designed to elicit different cognitive states. This results in a total of over 100 hours of open electrophysiological (EEG) and electrocardiogram (ECG) data. The project was validated by the local ethical committee of the University of Toulouse (CER number 2021-342). The dataset was validated on a subjective, behavioral and physiological level (i.e. cardiac and cerebral activity), to ensure its usefulness to the pBCI community. This body of work represents a large effort to promote the use of pBCIs, as well as the use of open science.

The data are in the Brain Imaging Data Structure (BIDS) format. For more information, please read the COG-BCI_info.pdf file.

We present simulation results from a study with The Virtual Brain (TVB). Structural, functional and simulated data have been prepared in accordance with Brain Imaging Data Structure (BIDS) standards and annotated according to the openMINDS metadata framework. This simultaneous electroencephalography (EEG) - functional magnetic resonance imaging (fMRI) resting-state data, diffusion-weighted MRI (dwMRI), and structural MRI were acquired for 50 healthy adult subjects (18 - 80 years of age, mean 41.24±18.33; 31 females, 19 males) at the Berlin Center for Advanced Imaging, Charité University Medicine, Berlin, Germany. We constructed personalized models from this multimodal data of 50 healthy individuals with TVB. We calculated the optimal parameters on an individual basis that predict multiple empirical features in fMRI and EEG, e.g. dynamic functional connectivity and bimodality in the alpha band power, and analyzed inter-individual differences with respect to optimized parameters and structural as well as functional connectivity in a previous study (Triebkorn et al. 2024). We present this large comprehensive empirical and simulated data set in an annotated and structured format following the BIDS Extension Proposal for computational modeling data. We describe how we processed and converted the diverse data sources to make it reusable. In its current form, this dataset can be reused for further research and provides ready-to-use data at various levels of processing including the thereof inferred brain simulation results for a large data set of healthy subjects with a wide age range.

This repository contains the EEG and behavioral data described in:

Fuglsang, S A, Märcher-Rørsted, J, Dau, T, Hjortkjær, J (2020). Effects of sensorineural hearing loss on cortical synchronization to competing speech during selective attention. Journal of Neuroscience, 40(12):2562–2572, https://doi.org/10.1523/JNEUROSCI.1936-19.2020

Please cite this paper when using the data

The data set consists of response data for 22 hearing-impaired and 22 normal-hearing participants. It includes:
- EEG data: responses to two-talker and single-talker speech stimuli
- Envelopes of the corresponding speech audio
- EEG data: responses to 1 kHz tone beeps for ERPs
- EEG data: responses to periodic tone sequences for Envelope-following responses (EFRs)
- EEG resting-state data recorded with eyes-open and eyes-closed
- inEar EEG data for 19 of the 44 subjects (EEG recorded inside the ear canals)
- Behavioral data: speech comprehension scores, task difficulty ratings, speech-in-noise scores (SRTs), tone-in-noise scores, digit span working memory scores, SSQ questionnaire ratings
- Pure-tone audiograms

For more information, see the README and 'dataset_description.json' file.

Format
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The dataset is formatted according to BIDS version 1.3.0 and the BIDS standard extension for EEG (BEP006) that has been merged in the main body of the specification. For more details, see https://bids-specification.readthedocs.io/en/latest/06-extensions.html

Behavioural data are stored in the 'participants.tsv' file. Task-difficulty ratings and multiple choice questionnaire data from the selective attention experiment are stored in the events files (see 'task-selectiveattention_events.json').

Code
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Code for analyzing the data is available at: https://gitlab.com/sfugl/snhl

Audio
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Envelopes of the audio signals are included in the data set. For inquiries regarding the raw audio data, please send an email to jensh@drcmr.dk with the subject line "ds-eeg-snhl audio".

Acknowledgments
----------
This work was supported by the EU H2020-ICT grant number 644732 (COCOHA: Cognitive Control of a Hearing Aid) and by the Novo Nordisk Foundation synergy grant NNF17OC0027872 (UHeal). The EarEEG were kindly provided by Eriksholm Research Centre.

Data comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four memory and cognitive tasks lasting approx. 1 hour. Gaze tracking on the task computer screen as well as pupilometry was also recorded together with behavioral performance. The recordings were collected from a minimum of one daily session (run) during a two-week long hospital stay for the seizure monitoring with at least one task from the battery completed. Each dataset comes from one patient and includes metadata about anatomical coordinates of every electrode contact, labels for each electrode contact channel, and timing of events in each task. All data are stored in BIDS (Brain Imaging Data Structure) format for efficient signal processing supported by the International Neuroinformatics Coordinating Facility), and were collected at Mayo Clinic (USA) or at the Wroclaw Medical University (Poland). These unique datasets arerelevant for anyone interested in neurology, neuroscience and neurophysiology of human memory and cognition. For more information visit the website of our Brain and Mind Electrophysiology laboratory (brainmindlab.com).

Dataset of intracranial EEG, scalp EEG and beamforming sources from human epilepsy patients performing a verbal working memory task

Description

We present an electrophysiological dataset recorded from fifteen subjects during a verbal working memory task. Subjects were epilepsy patients undergoing intracranial monitoring for localization of epileptic seizures. Subjects performed a modified Sternberg task in which the encoding of memory items, maintenance, and recall were temporally separated. The dataset includes simultaneously recorded scalp EEG with the 10-20 system, intracranial EEG (iEEG) recorded with depth electrodes, waveforms, and the MNI coordinates and anatomical labels of all intracranial electrodes. The dataset includes also reconstructed virtual sensor data that were created by performing LCMV beamforming on the EEG at specific brain regions including, temporal superior lobe, lateral prefrontal cortex, occipital cortex, posterior parietal cortex, and Broca. Subject characteristics and information on sessions (set size, match/mismatch, correct/incorrect, response, response time for each trial) are also provided. This dataset enables the investigation of working memory by providing simultaneous scalp EEG and iEEG recordings, which can be used for connectivity analysis, alongside reconstructed beamforming EEG sources that can enable further cognitive analysis such as replay of memory items.

Repository structure

Main directory (verbal WM)

Contains metadata files in the BIDS standard about the participants and the study. Folders are explained below.

Subfolders

• verbalWM/sub-/: Contains folders for each subject, named sub- and session information.
• verbalWM/sub-/ses-/ieeg/: Contains the raw iEEG data in .edf format for each subject. Each subject performed more than 1 working memory session (ses-0x) each of which includes ~50 trials. Each *ieeg.edf file contains continuous iEEG data during the working memory task. Details about the channels are given in the corresponding .tsv file. We also provide the information on the trial start and end in the events.tsv files by specifying the start and end sample of each trial.
• verbalWM/sub-/ses-/eeg/: Contains the raw EEG data in .edf format for each subject. Each subject performed more than 1 working memory session (ses-0x) each of which includes ~50 trials. Each *eeg.edf file contains continuous EEG data during the working memory task. Details about the channels are given in the corresponding .tsv file. We also provide the information on the trial start and end in the events.tsv files by specifying the start and end sample of each trial.
• verbalWM/derivatives/sub-/: Contains the LCMV beamforming sources during encoding and maintenance. The beamforming sources are in the form of virtual EEG sensors each of which corresponds to a specific brain region. The naming convention used for the virtual sensors is the following: DLPFC; dorsolateral pre-frontal cortex, OFC; orbitofrontal cortex, PPC; posterior parietal cortex, AC; auditory cortex, V1; primary visual cortex

BIDS Conversion

bids-starter-kid and custom Matlab scripts were used to convert the dataset into BIDS format.

References

[1] Dimakopoulos V, Megevand P, Stieglitz LH, Imbach L, Sarnthein J. Information flows from hippocampus to auditory cortex during replay of verbal working memory items. Elife 2022;11. 10.7554/eLife.78677

[2] Boran E, Fedele T, Klaver P, Hilfiker P, Stieglitz L, Grunwald T, et al. Persistent hippocampal neural firing and hippocampal-cortical coupling predict verbal working memory load. Science Advances 2019;5(3):eaav3687. 10.1126/sciadv.aav3687

[3] Boran E, Fedele T, Steiner A, Hilfiker P, Stieglitz L, Grunwald T, et al. Dataset of human medial temporal lobe neurons, scalp and intracranial EEG during a verbal working memory task. Scientific Data 2020;7(1):30. 10.1038/s41597-020-0364-3

References

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896). https://doi.org/10.21105/joss.01896

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8

Welcome to the resting state EEG dataset collected at the University of San Diego and curated by Alex Rockhill at the University of Oregon.

Please email arockhil@uoregon.edu before submitting a manuscript to be published in a peer-reviewed journal using this data, we wish to ensure that the data to be analyzed and interpreted with scientific integrity so as not to mislead the public about findings that may have clinical relevance. The purpose of this is to be responsible stewards of the data without an "available upon reasonable request" clause that we feel doesn't fully represent the open-source, reproducible ethos. The data is freely available to download so we cannot stop your publication if we don't support your methods and interpretation of findings, however, in being good data stewards, we would like to offer suggestions in the pre-publication stage so as to reduce conflict in published scientific literature. As far as credit, there is precedent for receiving a mention in the acknowledgements section for reading and providing feedback on the paper or, for more involved consulting, being included as an author may be warranted. The purpose of asking for this is not to inflate our number of authorships; we take ethical considerations of the best way to handle intellectual property in the form of manuscripts very seriously, and, again, sharing is at the discretion of the author although we strongly recommend it. Please be ethical and considerate in your use of this data and all open-source data and be sure to credit authors by citing them.

Note that UPDRS rating scales were collected by laboratory personnel who had completed online training and not a board-certified neurologist. Results should be interpreted accordingly, especially that analyses based largely on these ratings should be taken with the appropriate amount of uncertainty.

In addition to contacting the aforementioned email, please cite the following papers:

Nicko Jackson, Scott R. Cole, Bradley Voytek, Nicole C. Swann. Characteristics of Waveform Shape in Parkinson's Disease Detected with Scalp Electroencephalography. eNeuro 20 May 2019, 6 (3) ENEURO.0151-19.2019; DOI: 10.1523/ENEURO.0151-19.2019.

Swann NC, de Hemptinne C, Aron AR, Ostrem JL, Knight RT, Starr PA. Elevated synchrony in Parkinson disease detected with electroencephalography. Ann Neurol. 2015 Nov;78(5):742-50. doi: 10.1002/ana.24507. Epub 2015 Sep 2. PMID: 26290353; PMCID: PMC4623949.

George JS, Strunk J, Mak-McCully R, Houser M, Poizner H, Aron AR. Dopaminergic therapy in Parkinson's disease decreases cortical beta band coherence in the resting state and increases cortical beta band power during executive control. Neuroimage Clin. 2013 Aug 8;3:261-70. doi: 10.1016/j.nicl.2013.07.013. PMID: 24273711; PMCID: PMC3814961.

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896).

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8.

Note: see this discussion on the structure of the json files that is sufficient but not optimal and will hopefully be changed in future versions of BIDS: https://neurostars.org/t/behavior-metadata-without-tsv-event-data-related-to-a-neuroimaging-data/6768/25.

References

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896).https://doi.org/10.21105/joss.01896

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103.https://doi.org/10.1038/s41597-019-0104-8

Generated from raw data by MNE-BIDS (Appelhoff et al., 2019) and custom code to join to behavioural data, stimulus information, and metadata.

Notes on the Data

For full details on this dataset, see our preprint: (url here once out)

• An issue during recording meant that sub-05 completed the first block without data being saved. The experiment was restarted from the beginning for this participant. This participant was not included in our analyses, but the data are included in this dataset. They are also identified with the recording_restarted field in participants.tsv.

• A separate issue during recording meant that EEG data for some trials were lost for sub-01, though enough trials were recorded in total to meet our criteria for inclusion in the analysis. The raw data comprised two separate recordings. In this dataset, the two recordings are concatenated end-to-end into one file. The point at which the files are joined is marked with a boundary event. This participant is identified with the recording_interrupted field in participants.tsv.

• During the course of the experiment, we identified an issue with the wiring in one splitter box, which meant that voltages from channels FT7 and FC3 were swapped in the raw recorded data. We elected to keep the wiring as it was for the duration of the experiment, and then swapped the data from the two channels in the code that generated this BIDS dataset. This means that this issue has been corrected in this BIDS version of the data.

• "BAD" periods (MNE term) for key presses and break periods are included in the events files.

• Recording dates/times have been anonymised by shifting all recordings backwards in time by a constant number of days (same constant for all participants). This obscures information that may be used to identify participants, but preserves time-of-day information, and the relative times elapsed between different recordings.

References

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896). https://doi.org/10.21105/joss.01896

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8

0. Sections

1. Project
2. Dataset
3. Terms of Use
4. Contents

5. Method and Processing

1. PROJECT

Title: Brain-Computer Music Interface for Monitoring and Inducing Affective States (BCMI-MIdAS) Dates: 2012-2017 Funding organisation: Engineering and Physical Sciences Research Council (EPSRC) Grant no.: EP/J003077/1 and EP/J002135/1.

2. DATASET

EEG data from an affective Music Brain-Computer Interface: offline training to induce target emotional states. Description: This dataset accompanies the publication by Daly et al. (2018) and has been analysed in Daly et al. (2015) (please see Section 5 for full references). The purpose of the research activity in which the data were collected was to train a music brain-computer interface system to induce specific affective states for individual users. For this purpose the participants listened to music clips (40 s) targeting two affective states, as defined by valence and arousal. Data were recorded over 3 sessions (separate days), each containing 4 runs (same day) of 18 trials each. The music clips were generated using a synthetic music generator. The dataset contains the electroencephalogram (EEG), galvanic skin response (GSR) and electrocardiogram (ECG) data from 16 healthy participants while listening to the music clips, together with the reported affective state (valence and arousal values) and auxiliary variables.

This dataset is connected to 2 additional datasets:

1. EEG data from an affective Music Brain-Computer Interface: system calibration. doi:

2. EEG data from an affective Music Brain-Computer Interface: online real-time control. doi:

Please note that the number of participants varies between datasets; however, participant codes are the same across all three datasets.

Publication Year: 2018

Creators: Nicoletta Nicolaou, Ian Daly.

Contributors: Isil Poyraz Bilgin, James Weaver, Asad Malik, Alexis Kirke, Duncan Williams.

Principal Investigator: Slawomir Nasuto (EP/J003077/1).

Co-Investigator: Eduardo Miranda (EP/J002135/1).

Organisation: University of Reading

Rights-holders: University of Reading

Source: The synthetic generator used to generate the music clips was presented in Williams et al., “Affective Calibration of Musical Feature Sets in an Emotionally Intelligent Music Composition System”, ACM Trans. Appl. Percept. 14, 3, Article 17 (May 2017), 13 pages. DOI: https://doi.org/10.1145/3059005

3. TERMS OF USE

Copyright University of Reading, 2018. This dataset is licensed by the rights-holder(s) under a Creative Commons Attribution 4.0 International Licence: https://creativecommons.org/licenses/by/4.0/.

4. CONTENTS

The dataset comprises data from 17 subjects, stored using the BIDS format. The sampling rate is 1 kHz and the music listening task corresponding to a music clip is 40 s long (clip duration). During the first 20 s, the music clip targets emotional state A, while for the remaining 20 s the music clip targets emotional state B.

5. METHOD and PROCESSING

This information is available in the following publications:

[1] Daly, I., Nicolaou, N., Williams, D., Hwang, F., Kirke, A., Miranda, E., Nasuto, S.J., “Neural and physiological data from participants listening to affective music”, Scientific Data, 2018.

[2] Daly, I., Williams, D., Hwang, F., Kirke, A., Malik, A., Roesch, E., Weaver, J., Miranda, E. R., Nasuto, S. J., “Identifying music-induced emotions from EEG for use in brain-computer music interfacing”, in Proc. 4th Workshop on Affective Brain-Computer Interfaces at the 6th International Conference on Affective Computing and Intelligent Interaction (ACII2015). Xi’an, China, 21-25 September 2015. If you use this dataset in your study please cite these references, as well as the following reference:

[3] Williams, D., Kirke, A., Miranda, E.R., Daly, I., Hwang, F., Weaver, J., Nasuto, S.J., “Affective Calibration of Musical Feature Sets in an Emotionally Intelligent Music Composition System”, ACM Trans. Appl. Percept. 14, 3, Article 17 (May 2017), 13 pages. DOI: https://doi.org/10.1145/3059005

Thank you for your interest in our work.

Description

This is a data set consisting of simultaneous electroencephalography (EEG), electrospinography (ESG), electroneurography (ENG), and electromyography (EMG) recordings from 26 participants. There were nine different recording conditions: i) resting state with eyes open, ii) mixed median nerve stimulation (arm nerve), iii) mixed tibial nerve stimulation (leg nerve), iv) sensory nerve stimulation of the index finger, v) sensory nerve stimulation of the middle finger, vi) simultaneous senory nerve stimulation of the index and middle finger, vii) sensory nerve stimulation to the first toe, viii) sensory nerve stimulation to the second toe, ix) simultaneous senory nerve stimulation to the first and second toe. For each participant, there is i) the simultaneous EEG-ESG-ENG-EMG-recording which also includes electrocardiographic and respiratory signals, ii) ESG electrode positions. For a detailed description please see the following article: XXX. This study was pre-registered on OSF: https://osf.io/mjdha.

Citing this dataset

Should you make use of this data set in any publication, please cite the following article: XXXX

License

This data set is made available under the Creative Commons CC0 license. For more information, see https://creativecommons.org/share-your-work/public-domain/cc0/

Data set

This data set is organized according to the Brain Imaging Data Structure specification. For more information on this data specification, see https://bids-specification.readthedocs.io/en/stable/ Each participant's data are in one subdirectory (e.g., 'sub-001'), which contains the raw data in eeglab format. Please note that the EEG channel Fz was referenced to i) the EEG reference (right mastoid, RM, channel name: Fz) and ii) the ESG reference (6th thoracic vertebra, TH6, channel name: Fz-TH6). Should you have any questions about this data set, please contact nierula@cbs.mpg.de or eippert@cbs.mpg.de.

Note: only the data for participant 1 has been uploaded. The rest of the dataset will be released upon publication.

The analysis codes, results, and figures can be found on OSF: https://osf.io/r93es.

The main folder contains the raw EEG data in standard bids format.

The ‘derivatives’ folder contains the pre-processed & epoched EEG data, formatted in line with cosmomvpa.

For codes, results, & figures, see OSF: Engeler, P., Grootswagers, T., Robinson, A. K., Holcombe, A. O., Carlson, T. A., & Moerel, D. (2022, August 17). Rotation-tolerant representations elucidate the time course of high-level object processing. Retrieved from osf.io/r93es

The HBN-EEG Dataset

This is Release 9 of HBN-EEG, the EEG and (soon-released) Eye-Tracking Section of the Child Mind Network Healthy Brain Network (HBN) Project, curated into the Brain Imaging Data Structure (BIDS) format. This dataset is part of a larger initiative to advance the understanding of child and adolescent mental health through collecting and analyzing neuroimaging, behavioral, and genetic data (Alexander et al., Sci Data 2017).

Data Description

This dataset comprises electroencephalogram (EEG) data and behavioral responses collected during EEG experiments from participants involved in the HBN project.

Contents

• EEG Data: High-resolution EEG recordings capture a wide range of neural activity during various tasks.
• Behavioral Responses: Participant responses during EEG tasks, including reaction times and accuracy. This data was originally recorded within the behavior directory of the HBN data. The data is now included with the EEG data within the _events.tsv files.

Special Features

• Hierarchical Event Descriptors (HED): Events, including the original EEG events and the included behavioral events, have clear explanations, including proper HED annotation suitable for systematic meta and mega analysis of the data.
• P-Factor, Attention, Internalization and Externalization: Derived from the CBCL questionnaire, these factors provide valuable insights into the psychopathology of the participants, adding a rich layer of interpretation to the EEG and behavioral data.
• Data quality and availability: We performed minimal quality control to ensure that the data was not corrupted, each task had its necessary events, and was ready for preprocessing. The results of this quality control are available in the participants.tsv file.
• Future Releases: We are committed to enhancing this dataset with additional, valuable features in its next stages, including:
  • Personalized EEG Electrode Locations: To offer more detailed insights into individual neural activity patterns.
  • Personalized Lead Field Matrix: Enabling better understanding and interpretation of EEG data.
  • Eye-Tracking Data: Providing a window into the visual attention and processing mechanisms during EEG experiments.

Copyright and License

This dataset is licensed under the Creative Commons Attribution 4.0 International License (CC BY SA 4.0). Please cite the original HBN publication (https://dx.doi.org/10.1038/sdata.2017.181) as well as the dataset paper (https://doi.org/10.1101/2024.10.03.615261).

Acknowledgments

We would like to express our gratitude to all participants and their families, whose contributions have made this project possible. We also thank our dedicated team of researchers and clinicians for their efforts in collecting, processing, and curating this data.

Overview

This dataset was collected in 2023 and comprises electroencephalography, physiological and behavioural data acquired from 73 healthy individuals (ages: 21-45). The task was administered as part of a larger study.

Task Description

Fake Face (FF)

The objective of the study was to investigate if emotional arousal would affect people's perceived realness of others' faces, given ambiguous information. To manipulate participants' emotional arousal, images of angry (high emotionality) and neutral (low emotionality) faces (selected based on the their rated intensity from the NimStim Set of Facial Expressions (Tottenham et al., 2009)), were used as subliminal primes and facial images from the Multi-Racial Mega-Resolution database (Strohminger et al., 2016) were used as target stimuli. Blank screens were flashed prior to the target presentation in control trials. Forward and backward masks, generated by scrambling the primes, were implemented to prevent the primes from breaking awareness.

Each participant underwent a total of 222 trials, comprising of a forward mask,followed by the prime and backward mask, before the presentation of the target stimuli. The primes and targets were presented in a randomized order and trials were administered over a course of 3 blocks, between which participants were given a break to rest before proceeding to the next block of trials. During the presentation of the target stimulus, participants were instructed to indicate whether they thought the target was real or fake in a limited span of time (750ms), after which participants rated their confidence in their response using a sliding scale (0-100).

Data acquisition

EEG data acquisition

EEG signals were recorded using the EasyCap 64-channel and BrainVision Recording system. Electrodes were placed on the EEG cap according to the standard 10-5 system of electrode placement (Oostenveld & Praamsrta, 2001) and impedance was kept below 12 kOhm for each subject. The ground electrode was placed on the forehead the Cz was used as the reference channel. During recording, the sampling rate was 10000Hz. Note that channels Tp9 and Tp10 were placed near the outer canthi of each eye, and POz as well as Oz were fixed above and below one of the eyes to measure the E0G.

Physiological data acquisition

Participants' physiological signals, that is their electrocardiogram (ECG), photoplethysmograph (PPG) and respiration signals (RSP), were obtained at a sampling frequency of 1000Hz. All physiological signals were recorded via the PLUX OpenSignals software and BITalino Toolkit.

ECG was collected using three ECG electrodes placed according to a modified Lead II configuration, and RSP was acquired using a respiration belt tightened over participants' upper abdomen. PPG sensors, which record changes in blood volume, were clipped on the tip of the index finger of participants' non-dominant hand to meaure heart rate and oxygen saturation.

References

Appelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896). https://doi.org/10.21105/joss.01896

Pernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8