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TwitterIn 2022, the mortality rate of breast cancer in women in Europe was **** per 100,000 women. Cyprus had the highest mortality rate at **** per 100,000, followed by Slovakia with **** per 100,000 women. Conversely, Spain had the lowest mortality rate at **** per 100,000. This statistic depicts the mortality rate of breast cancer in Europe in 2022 in women population, by country.
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TwitterIn 2020, Melanesia was the region with the highest death rate due to breast cancer worldwide, with around 27.5 deaths per 100,000 women. This statistic shows the age-standardized mortality rate (deaths) of breast cancer among women worldwide, by region.
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Dataset Description This dataset contains information on cancer deaths by country, type, and year. It includes data on 18 different types of cancer, including liver cancer, kidney cancer, larynx cancer, breast cancer, thyroid cancer, stomach cancer, bladder cancer, uterine cancer, ovarian cancer, cervical cancer, prostate cancer, pancreatic cancer, esophageal cancer, testicular cancer, nasopharynx cancer, other pharynx cancer, colon and rectum cancer, non-melanoma skin cancer, lip and oral cavity cancer, brain and nervous system cancer, tracheal, bronchus, and lung cancer, gallbladder and biliary tract cancer, malignant skin melanoma, leukemia, Hodgkin lymphoma, multiple myeloma, and other cancers.
Data Fields The dataset includes the following data fields:
Data Source The data in this dataset was collected from the World Health Organization (WHO). The WHO collects data on cancer deaths from countries around the world.
Usage This dataset can be used to study cancer deaths by country, type, and year. It can also be used to compare cancer death rates between different countries or over time.
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BackgroundAmidst the rising breast cancer burden in Asia, we aim to predict the future mortality risk due to breast cancer and identify the risk-attributable deaths for breast cancer among East and South Asian countries.MethodsWe used country-level data to predict the trends in the next decade relating to female breast cancer mortality by employing data from 1990 to 2019 from the Global Burden of Disease 2019 study. We used the stochastic mortality modeling and prediction techniques to forecast the age-specific and risk-attributable breast cancer mortality trends at the regional and national levels of East and South Asia.ResultsThe number of deaths caused by the breast cancer is predicted to increase in East and South Asian countries in the next decade (2020–2030). Age-standardized death rate (ASDR) of breast cancer is predicted to increase by 7.0% from 9.20/100,000 (95% CI: 6.04–12.12) in 1990 to 9.88/100,000 (95% CI: 7.12–11.4) in 2030 in East Asia, and about 35% increase from 13.4/100,000 (95% CI: 9.21–16.02) in 1990 to 18.1/100,000 (95% CI: 13.23–21.10) in 2030 in South Asia. At the national level, the highest percent change in ASDR between 1990 and 2030 was reported in Pakistan (a 62% increase) and Nepal (a 47% increase). The highest percent change in breast cancer mortality between 2020 and 2030 for females of age group 80–84 years was observed in Pakistan [21.6, (95% CI, 20.6–94.7)], followed by Afghanistan [13.3 (4.0–80.8)], and Nepal [36.6 (11.1–125.7)] as compared to the other countries. In the females of aged 50–80 years, the predicted death rates were associated with high body mass index, high-fasting plasma glucose, and diet high in red meat, across the majority of countries under study. Furthermore, reductions in percent change in mortality rates occurred in several countries with increases in sociodemographic index (SDI), notably across high SDI countries.ConclusionBreast cancer mortality risk varies substantially across East and South Asian countries with higher mortality risk in low/middle SDI countries. Early detection using screening, awareness among females and health workers, and cost-effective and timely treatment of patients with breast cancer is vital in stemming the tide of breast cancer in the next decade.
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(Source: WHO, American Cancer Society)
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TwitterThe Latin American country with the highest age-standardized cancer mortality rate in 2022 was Uruguay, with ***** deaths per 100,000 population. Jamaica and Barbados followed, with cancer mortality rates of ***** and *****, respectively. As of that year, breast cancer was the cancer type with the highest incidence rate in Uruguay, as approximately ***** new cases were reported in the country.
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Multivariable Cox regression analysis model for survival of female breast cancer patients in southern Ethiopia, 2013–2018 (n = 302).
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TwitterBreast cancer was the cancer type with the highest rate of death among females worldwide in 2022. That year, there were around 13 deaths from breast cancer among females per 100,000 population. The death rate for all cancers among females was 76.4 per 100,000 population. This statistic displays the rate of cancer deaths among females worldwide in 2022, by type of cancer.
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📄 Dataset Description: This dataset contains global cancer patient data reported from 2015 to 2024, designed to simulate the key factors influencing cancer diagnosis, treatment, and survival. It includes a variety of features that are commonly studied in the medical field, such as age, gender, cancer type, environmental factors, and lifestyle behaviors. The dataset is perfect for:
Exploratory Data Analysis (EDA)
Multiple Linear Regression and other modeling tasks
Feature Selection and Correlation Analysis
Predictive Modeling for cancer severity, treatment cost, and survival prediction
Data Visualization and creating insightful graphs
Key Features: Age: Patient's age (20-90 years)
Gender: Male, Female, or Other
Country/Region: Country or region of the patient
Cancer Type: Various types of cancer (e.g., Breast, Lung, Colon)
Cancer Stage: Stage 0 to Stage IV
Risk Factors: Includes genetic risk, air pollution, alcohol use, smoking, obesity, etc.
Treatment Cost: Estimated cost of cancer treatment (in USD)
Survival Years: Years survived since diagnosis
Severity Score: A composite score representing cancer severity
This dataset provides a broad view of global cancer trends, making it an ideal resource for those learning data science, machine learning, and statistical analysis in healthcare.
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Log-rank test for equality of survival function of female breast cancer patients in southern Ethiopia, 2013–2018 (n = 302).
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Breast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gland. The molecular subtypes of breast cancer, which are based on the presence or absence of hormone receptors (estrogen and progesterone subtypes) and human epidermal growth factor receptor-2 (HER2), include: * Luminal A subtype: Hormone receptor positive (progesterone and estrogen) and HER2 (ERBB2) negative * Luminal B subtype: Hormone receptor positive (progesterone and estrogen) and HER2 (ERBB2) positive * HER2 positive: Hormone receptor negative (progesterone and estrogen) and HER2 (ERBB2) positive * Basal-like or triple-negative (TNBCs): Hormone receptor negative (progesterone and estrogen) and HER2 (ERBB2) negative Hormone receptor positive breast cancers are largely driven by the estrogen/ER pathway. In HER2 positive breast tumors, HER2 activates the PI3K/AKT and the RAS/RAF/MAPK pathways, and stimulate cell growth, survival and differentiation. In patients suffering from TNBC, the deregulation of various signaling pathways (Notch and Wnt/beta-catenin), EGFR protein have been confirmed. In the case of breast cancer only 8% of all cancers are hereditary, a phenomenon linked to genetic changes in BRCA1 or BRCA2. Somatic mutations in only three genes (TP53, PIK3CA and GATA3) occurred at >10% incidence across all breast cancers. Phosphorylation sites were added based on information from PhosphoSitePlus (R), www.phosphosite.org.
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Baseline characteristics of female breast cancer patients in southern Ethiopia, 2013–2018 (n = 302).
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TwitterAs of 2023, the countries with the highest death rates worldwide were Monaco, Bulgaria, and Latvia. In these countries, there were ** to ** deaths per 1,000 people. The country with the lowest death rate is Qatar, where there is just *** death per 1,000 people. Leading causes of death The leading causes of death worldwide are, by far, cardiovascular diseases, accounting for ** percent of all deaths in 2021. That year, there were **** million deaths worldwide from ischaemic heart disease and **** million from stroke. Interestingly, a worldwide survey from that year found that people greatly underestimate the proportion of deaths caused by cardiovascular disease, but overestimate the proportion of deaths caused by suicide, interpersonal violence, and substance use disorders. Death in the United States In 2023, there were around **** million deaths in the United States. The leading causes of death in the United States are currently heart disease and cancer, accounting for a combined ** percent of all deaths in 2023. Lung and bronchus cancer is the deadliest form of cancer worldwide, as well as in the United States. In the U.S. this form of cancer is predicted to cause around ****** deaths among men alone in the year 2025. Prostate cancer is the second-deadliest cancer for men in the U.S. while breast cancer is the second deadliest for women. In 2023, the tenth leading cause of death in the United States was COVID-19. Deaths due to COVID-19 resulted in a significant rise in the total number of deaths in the U.S. in 2020 and 2021 compared to 2019, and it was the third leading cause of death in the U.S. during those years.
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TwitterPurposesMost molecular-based published studies on breast cancer do not adequately represent the unique and diverse genetic admixture of the Latin American population. Searching for similarities and differences in molecular pathways associated with these tumors and evaluating its impact on prognosis may help to select better therapeutic approaches.Patients and MethodsWe collected clinical, pathological, and transcriptomic data of a multi-country Latin American cohort of 1,071 stage II-III breast cancer patients of the Molecular Profile of Breast Cancer Study (MPBCS) cohort. The 5-year prognostic ability of intrinsic (transcriptomic-based) PAM50 and immunohistochemical classifications, both at the cancer-specific (OSC) and disease-free survival (DFS) stages, was compared. Pathway analyses (GSEA, GSVA and MetaCore) were performed to explore differences among intrinsic subtypes.ResultsPAM50 classification of the MPBCS cohort defined 42·6% of tumors as LumA, 21·3% as LumB, 13·3% as HER2E and 16·6% as Basal. Both OSC and DFS for LumA tumors were significantly better than for other subtypes, while Basal tumors had the worst prognosis. While the prognostic power of traditional subtypes calculated with hormone receptors (HR), HER2 and Ki67 determinations showed an acceptable performance, PAM50-derived risk of recurrence best discriminated low, intermediate and high-risk groups. Transcriptomic pathway analysis showed high proliferation (i.e. cell cycle control and DNA damage repair) associated with LumB, HER2E and Basal tumors, and a strong dependency on the estrogen pathway for LumA. Terms related to both innate and adaptive immune responses were seen predominantly upregulated in Basal tumors, and, to a lesser extent, in HER2E, with respect to LumA and B tumors.ConclusionsThis is the first study that assesses molecular features at the transcriptomic level in a multicountry Latin American breast cancer patient cohort. Hormone-related and proliferation pathways that predominate in PAM50 and other breast cancer molecular classifications are also the main tumor-driving mechanisms in this cohort and have prognostic power. The immune-related features seen in the most aggressive subtypes may pave the way for therapeutic approaches not yet disseminated in Latin America.Clinical Trial RegistrationClinicalTrials.gov (Identifier: NCT02326857).
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TwitterThe American Cancer Society estimates that there will be 2.7 million new instances of breast cancer identified in 2021, with 721,000 fatalities expected to result from the disease. Breast cancer is one of the leading causes of mortality among women worldwide. The kind of breast cancer known as invasive ductal carcinoma (IDC) accounts for approximately 77% of all occurrences of breast cancer that are detected. When it comes to selecting the appropriate treatment plan and increasing the overall survival percentage of patients, making an accurate diagnosis as soon as possible is of critical importance. Because of recent developments in slide scanning technology as well as a decrease in the cost of digital storage over the past several years, microscopic assessment of histopathologic stained tissue and its subsequent digitalization is now a more practical option than it was in the past. The use of digital pathology brings with it a number of benefits, some of which being remote diagnosis, immediate access to historical materials, and a streamlined process for consultations with qualified pathologists. As a possible diagnostic tool and approach, digitalized analysis that is based on deep learning has demonstrated that it may offer some benefits.
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TwitterBreast cancer is the most common cancer in women, and this prevalence has a major impact on health worldwide. Localized breast cancer has an excellent prognosis, with a 5-year relative survival rate of 85%. However, the survival rate drops to only 23% for women with distant metastases. To date, the study of breast cancer metastasis has been hampered by a lack of reliable metastatic models. Here we describe a novel in vivo model using human breast cancer xenografts in NOD scid gamma (NSG) mice; in this model human breast cancer cells reliably metastasize to distant organs from primary tumors grown within the mammary fat pad. This model enables the study of the entire metastatic process from the proper anatomical site, providing an important new approach to examine the mechanisms underlying breast cancer metastasis. We used this model to identify gene expression changes that occur at metastatic sites relative to the primary mammary fat pad tumor. By comparing multiple metastatic sites and independent cell lines, we have identified several gene expression changes that may be important for tumor growth at distant sites.
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Background: Breast cancer in young women is quite uncommon and shows more aggressive characteristics with major disparities between worldwide populations. Prognosis and outcome of breast cancer in young patients are widely studied, but still no consensus is available. Methods: We retrospectively included 716 cases of breast cancer women diagnosed in 2009 at the National Institute of Oncology of Rabat. Patients were divided into two groups according to their age: women aged ≤40 years (Group 1) and women aged >40 years (Group 2). Data were recorded from patients' medical files and analyzed using SPSS 13.0 software (IBM). Results: Young patients represent 24.9% of all patients with breast cancer. The comparison between the two groups displayed significant differences regarding nulliparity (p = 0.001) and progesterone receptor negativity (p = 0.01). Moreover, more progression (Metastases/Relapse) was registered in young women as compared to older women with breast cancer (p = 0.03). The estimated median follow-up period was 31 months. The 5-years Event-Free Survival (EFS) of patients with local disease was 64.6% in young women and 71.5% in older women with breast cancer (p = 0.04). Multivariate analysis in young women showed that nulliparity (HR: 7.2; 95%CI: 1.16–44.54; p = 0.03), T3 tumors (HR: 17.39; 95%CI: 1.74–173.34; p = 0.01) and negative PgR status (HR: 19.85; 95%CI: 1.07–366.54; p = 0.04) can be considered as risk factors for poorer event free survival while hormone therapy was associated with better EFS (HR: 0.11; 95%CI: 0.00–0.75; p = 0.03). In Group 2, multivariate analysis showed that patients with inflammatory breast cancer, N+ status, absence of radiotherapy, absence of chemotherapy, and absence of hormone therapy are at increased risk of recurrence. Conclusions: In Morocco, breast cancer is more frequent in young women as compared to western countries. Breast cancer in young women is more aggressive and is diagnosed late, leading to an intensive treatment. Moreover, the main factors associated with breast cancer development in young women would be hormonal and reproductive status. Analysis of other genetic biomarkers is needed to explain the high prevalence of breast cancer in young women to improve breast cancer management in Morocco
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Background and aimThis study aims to analyze the worldwide prevalence, mortality rates, and disability-adjusted life years (DALYs) attributed to breast cancer in women between 1990 and 2019. Additionally, it seeks to forecast the future trends of these indicators related to the burden of breast cancer in women from 2020 to 2030.MethodsData from the Global Burden of Disease Study (GBD) 2019 was analyzed to determine the age-standardized incidence rate (ASIR) and age-standardized death rate (ASDR) of DALYs due to breast cancer in women across 204 countries and territories from 1990 to 2019. Socio-economic development levels of countries and regions were assessed using Socio-demographic Indexes, and trends in the burden of breast cancer in women worldwide from 2020 to 2030 were projected using generalized additive models (GAMs).ResultsThe estimated annual percentage change (EAPC) in the ASIR breast cancer in women globally was 0.36 from 1990 to 2019 and is expected to increase to 0.44 from 2020 to 2030. In 2019, the ASIR of breast cancer in women worldwide was 45.86 and is projected to reach 48.09 by 2030. The burden of breast cancer in women generally rises with age, with the highest burden expected in the 45–49 age group from 2020 to 2030. The fastest increase in burden is anticipated in Central sub-Saharan Africa (EAPC in the age-standardized death rate: 1.62, EAPC in the age-standardized DALY rate: 1.52), with the Solomon Islands (EAPC in the ASIR: 7.25) and China (EAPC in the ASIR: 2.83) projected to experience significant increases. Furthermore, a strong positive correlation was found between the ASIR breast cancer in women globally in 1990 and the projected rates for 2030 (r = 0.62).ConclusionThe anticipated increase in the ASIR of breast cancer in women globally by 2030 highlights the importance of focusing on women aged 45–49 in Central sub-Saharan Africa, Oceania, the Solomon Islands, and China. Initiatives such as breast cancer information registries, raising awareness of risk factors and incidence, and implementing universal screening programs and diagnostic tests are essential in reducing the burden of breast cancer and its associated morbidity and mortality.
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The global breast cancer diagnostic market size was valued at approximately USD 4.5 billion in 2023 and is projected to reach USD 9.2 billion by 2032, growing at a compound annual growth rate (CAGR) of 8.5% during the forecast period. The rising prevalence of breast cancer, coupled with advances in diagnostic technologies, significantly drives the market growth. Other factors include increased awareness about early detection and the availability of substantial government funding for cancer research and diagnostics.
One of the primary growth factors in the breast cancer diagnostic market is the increasing incidence of breast cancer globally. According to the World Health Organization (WHO), breast cancer is the most common cancer among women worldwide, leading to significant morbidity and mortality. The rising awareness about the importance of early diagnosis, which significantly improves survival rates, has encouraged more women to undergo regular screenings. This has, in turn, driven the demand for advanced diagnostic tools and technologies.
Technological advancements in diagnostic tools are another critical growth driver for the breast cancer diagnostic market. Innovations such as digital mammography, 3D imaging, and artificial intelligence (AI)-driven diagnostic solutions have revolutionized the early detection and accurate diagnosis of breast cancer. These technologies offer enhanced image clarity, reduced false positives, and faster results, leading to better patient outcomes. Continuous research and development in this area are expected to bring more sophisticated and effective diagnostic solutions to the market.
The increasing availability of government and private funding for breast cancer research and diagnostic initiatives also propels market growth. Many countries have implemented screening programs and awareness campaigns to educate women about the importance of early detection. Additionally, several non-profit organizations and advocacy groups are actively involved in promoting breast cancer awareness and funding research projects, further boosting the demand for diagnostic services.
From a regional perspective, North America dominates the breast cancer diagnostic market, followed by Europe, due to the high prevalence of breast cancer, well-established healthcare infrastructure, and significant investment in research and development. The Asia Pacific region is expected to witness the highest growth rate during the forecast period, driven by increasing awareness, improving healthcare facilities, and rising healthcare expenditure in countries such as China and India.
The breast cancer diagnostic market can be segmented by test type into mammography, biopsy, ultrasound, MRI, CT scan, PET scan, and others. Mammography is the most commonly used test for breast cancer screening and diagnosis. Digital mammography, which offers superior image quality and lower radiation exposure compared to traditional film mammography, has gained significant traction. The advent of 3D mammography or tomosynthesis has further enhanced the accuracy of breast cancer detection, reducing false positives and improving patient outcomes.
Biopsy remains the gold standard for definitive diagnosis of breast cancer. Various biopsy techniques such as fine-needle aspiration, core needle biopsy, and surgical biopsy are employed based on the clinical scenario. The integration of imaging technologies with biopsy procedures, such as stereotactic and ultrasound-guided biopsies, has improved the precision and accuracy of tissue sampling, thereby enhancing diagnostic outcomes. The development of minimally invasive biopsy techniques has also reduced patient discomfort and recovery time.
Ultrasound is commonly used as an adjunct to mammography to evaluate breast abnormalities, particularly in women with dense breast tissue. The non-invasive nature of ultrasound, combined with its ability to differentiate between cystic and solid masses, makes it a valuable tool in breast cancer diagnosis. Advances in ultrasound technology, such as the development of elastography, have further improved its diagnostic accuracy by assessing tissue stiffness, which is indicative of malignancy.
MRI and PET scans are primarily used for staging breast cancer and evaluating the extent of disease spread. MRI offers excellent soft tissue contrast and is particularly useful in assessing the involvement of the chest wall and lymph nodes. PET scans, on the other hand, provide functional
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As per our latest research, the global breast cancer therapeutics market size reached USD 27.8 billion in 2024, reflecting robust growth driven by technological advancements and increasing disease prevalence worldwide. The market is poised to expand at a CAGR of 8.6% during the forecast period, with projections indicating the market will attain a value of USD 57.3 billion by 2033. This remarkable growth trajectory is underpinned by rising awareness regarding early diagnosis, expanding access to advanced therapies, and continuous innovation in targeted treatments. The breast cancer therapeutics market is experiencing a transformative phase, with significant investments in research and development, fostering the introduction of novel drugs and personalized medicine approaches.
One of the primary growth factors for the breast cancer therapeutics market is the increasing incidence and prevalence of breast cancer globally. According to the World Health Organization, breast cancer remains the most common cancer among women, accounting for nearly 2.3 million new cases annually. The rising burden of this disease, coupled with the aging population and lifestyle-related risk factors, has heightened the demand for effective therapeutic interventions. Furthermore, the growing emphasis on routine screening and early detection initiatives has led to a surge in diagnosed cases, necessitating timely and advanced treatment options. The integration of artificial intelligence and digital health solutions in diagnostics and treatment planning is also contributing to improved patient outcomes and driving market expansion.
Another significant driver is the rapid advancement in drug development, particularly in targeted therapy and immunotherapy. Pharmaceutical companies are increasingly focusing on the development and commercialization of monoclonal antibodies, hormone therapies, and novel immunotherapeutics that offer superior efficacy and safety profiles compared to conventional chemotherapy. The approval of innovative drugs such as CDK4/6 inhibitors, PARP inhibitors, and immune checkpoint inhibitors has revolutionized the treatment landscape, enabling personalized and precision medicine approaches. These advancements are not only enhancing survival rates but also improving the quality of life for breast cancer patients. Additionally, supportive government initiatives, favorable reimbursement policies, and expanding clinical trial activities are further catalyzing market growth.
The expanding availability and accessibility of breast cancer therapeutics in emerging markets are also contributing to market growth. Countries in Asia Pacific and Latin America are witnessing increased healthcare investments, improved infrastructure, and rising awareness about cancer prevention and treatment. This has led to greater adoption of advanced therapies and a shift towards patient-centric care models. Moreover, collaborations between global pharmaceutical companies and local healthcare providers are facilitating the introduction of novel therapeutics in these regions. The growing penetration of online pharmacies and telemedicine platforms is also enhancing access to breast cancer drugs, especially in remote and underserved areas.
From a regional perspective, North America continues to dominate the breast cancer therapeutics market, accounting for the largest share in 2024, driven by high healthcare expenditure, advanced research capabilities, and a well-established regulatory framework. Europe follows closely, with significant contributions from countries like Germany, France, and the United Kingdom. The Asia Pacific region is anticipated to exhibit the fastest growth during the forecast period, owing to rising cancer incidence, increasing healthcare investments, and expanding patient access to innovative therapies. Latin America and the Middle East & Africa are also expected to witness steady growth, supported by improving healthcare infrastructure and growing awareness about breast cancer management.
The breast cancer therapeutics market is segmented by therapy type into chemotherapy, hormone therapy, targeted therapy, immunotherapy, and others. Chemotherapy remains a cornerstone of breast cancer treatment, particularly for advanced and metastatic cases. Despite the emergence of newer therapies, chemotherapy continues to be widely used due to its proven efficacy in reducing tumor burden and preventing disease recurrence. However, the ma
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TwitterIn 2022, the mortality rate of breast cancer in women in Europe was **** per 100,000 women. Cyprus had the highest mortality rate at **** per 100,000, followed by Slovakia with **** per 100,000 women. Conversely, Spain had the lowest mortality rate at **** per 100,000. This statistic depicts the mortality rate of breast cancer in Europe in 2022 in women population, by country.