In 2022, the country with the highest age-standardized cancer incidence rate in Latin America and the Caribbean was Uruguay, with 279.9 new cases per 100,000 population. Cuba and Argentina followed, with cancer incidence rates of 220.8 and 215.8, respectively. In that year, Uruguay was also the country with the highest cancer mortality rate in the region.

In 2022, the highest cancer rate for men and women among European countries was in Denmark with 728.5 cancer cases per 100,000 population. Ireland and the Netherlands followed, with 641.6 and 641.4 people diagnosed with cancer per 100,000 population, respectively.
Lung cancer Lung cancer is the deadliest type of cancer worldwide, and in Europe, Germany was the country with the highest number of lung cancer deaths in 2022, with 47.7 thousand deaths. However, when looking at the incidence rate of lung cancer, Hungary had the highest for both males and females, with 138.4 and 72.3 cases per 100,000 population, respectively.
Breast cancer Breast cancer is the most common type of cancer among women with an incidence rate of 83.3 cases per 100,000 population in Europe in 2022. Cyprus was the country with the highest incidence of breast cancer, followed by Belgium and France. The mortality rate due to breast cancer was 34.8 deaths per 100,000 population across Europe, and Cyprus was again the country with the highest figure.

In 2022, Australia had the fourth-highest total number of skin cancer cases worldwide and the highest age-standardized rate, with roughly 37 cases of skin cancer per 100,000 population. The graph illustrates the rate of skin cancer in the countries with the highest skin cancer rates worldwide in 2022.

To investigate the global incidence of prostate cancer with special attention to the changing age structures. Data regarding the cancer incidence and population statistics were retrieved from the International Agency for Research on Cancer in World Health Organization. Eight developing and developed jurisdictions in Asia and the Western countries were selected for global comparison. Time series were constructed based on the cancer incidence rates from 1988 to 2007. The incidence rate of the population aged ≥ 65 was adjusted by the increasing proportion of elderly population, and was defined as the “aging-adjusted incidence rate”. Cancer incidence and population were then projected to 2030. The aging-adjusted incidence rates of prostate cancer in Asia (Hong Kong, Japan and China) and the developing Western countries (Costa Rica and Croatia) had increased progressively with time. In the developed Western countries (the United States, the United Kingdom and Sweden), we observed initial increases in the aging-adjusted incidence rates of prostate cancer, which then gradually plateaued and even decreased with time. Projections showed that the aging-adjusted incidence rates of prostate cancer in Asia and the developing Western countries were expected to increase in much larger extents than the developed Western countries.

In 2022, the highest breast cancer incidence in women in Europe was estimated in Luxembourg with approximately 190 per 100,000 population. Belgium and Cyprus followed closely. The average breast cancer incidence across EU-27 was 147.6 per 100,00 population, in 2022. Cancer incidence in Europe In 2022, Denmark was the European country with the highest cancer incidence, with 728.5 cases per 100,000 population, followed by Ireland and Netherlands, with both around 641 cases per 100,000 people. Overall, the age-standardized incidence rate of cancer in all sites, excluding non-melanoma skin cancers, was 568.7 per 100,000 population in the whole of EU, with the most prevalent type of cancer being prostate cancer, followed by breast and colorectal cancer. Deaths from breast cancer In the same year, breast cancer also had the highest mortality rate among all types of cancers in women, standing at 34.1 deaths per 100,000 females. Cyprus had the highest mortality rate from breast cancer in all of EU with 45.1 deaths per 100,000 women. Meanwhile, the highest number of deaths due to breast cancer in the given year was reported in Germany, where approximately 20.6 thousand women lost their lives to breast cancer.

ObjectiveWe investigated whether there are differences in cancer incidence by geographical area of origin in North-eastern Italy.MethodsWe selected all incident cases recorded in the Veneto Tumour Registry in the period 2015-2019. Subjects were classified, based on the country of birth, in six geographical areas of origin (Italy, Highly Developed Countries-HDC, Eastern Europe, Asia, Africa, South-central America). Age-standardized incidence rates and incidence rate ratio (IRR) were calculated, for all cancer sites and for colorectal, liver, breast and cervical cancer separately.ResultsWe recorded 159,486 all-site cancer cases; 5.2% cases occurred in subjects born outside Italy, the majority from High Migratory Pressure Countries (HMPC) (74.3%). Incidence rates were significantly lower in subjects born in HMPC in both sexes. Immigrants, in particular born in Asia and Africa, showed lower rates of all site cancer incidence. The lowest IRR for colorectal cancer was observed in males from South-Central America (IRR 0.19, 95%CI 0.09-0.44) and in females from Asia (IRR 0.32, 95%CI 0.18-0.70). The IRR of breast cancer appeared significantly lower than Italian natives in all female populations, except for those coming from HDC. Females from Eastern Europe showed a higher IRR for cervical cancer (IRR 2.02, 95%CI 1.57-2.61).ConclusionCancer incidence was found lower in subjects born outside Italy, with differences in incidence patterns depending on geographical area of origin and the cancer type in question. Further studies, focused on the country of birth of the immigrant population, would help to identify specific risk factors influencing cancer incidence.

This statistic depicts cancer incidence rates among men in selected countries worldwide between 2003 and 2007, per 100,000 inhabitants. African American men have one of the highest cancer incidence rates worldwide, with 446.1 new cases per 100,000 inhabitants.

Users can access data about cancer statistics, specifically incidence and mortality worldwide for the 27 major types of cancer. Background Cancer Mondial is maintained by the Section of Cancer Information (CIN) of International Agency for Research on Cancer by the World Health Organization. Users can access CIN databases including GLOBOCAN, CI5(Cancer Incidence in Five Continents), WHO, ACCIS(Automated Childhood Cancer Information System), ECO (European Cancer Observatory), NORDCAN and Survcan. User functionality Users can access a variety of databases. CIN Databases: GLOBOCAN provides acces s to the most recent estimates (for 2008) of the incidence of 27 major cancers and mortality from 27 major cancers worldwide. CI5 (Cancer Incidence in Five Continents) provides access to detailed information on the incidence of cancer recorded by cancer registries (regional or national) worldwide. WHO presents long time series of selected cancer mortality recorded in selected countries of the world. Collaborative projects: ACCIS (Automated Childhood Cancer Information System) provides access to data on cancer incidence and survival of children collected by European cancer registries. ECO (European Cancer Observatory) provides access to the estimates (for 2008) of the incidence of, and mortality f rom 25 major cancers in the countries of the European Union (EU-27). NORDCAN presents up-to-date long time series of cancer incidence, mortality, prevalence and survival from 40 cancers recorded by the Nordic countries. SurvCan presents cancer survival data from cancer registries in low and middle income regions of the world. Data Notes Data is available in different formats depending on which type of data is accessed. Some data is available in table, PDF, and html formats. Detailed information about the data is available.

It was estimated that in 2018 there were 20 cervical cancer deaths per 100,000 women in Southern Africa. Most cervical cancer cases are due to human papillomavirus (HPV), which is the most common sexually transmitted infection worldwide.

According to Cognitive Market Research, the global Cancer Cachexia market size is USD XX million in 2024 and will expand at a compound annual growth rate (CAGR) of XX from 2024 to 2031.

• The global Cancer Cachexia market will expand significantly by XX% CAGR between 2024 and 2031. • North America held a market of around XX% of the global revenue with a market size of USD XX million in 2024 and will grow at a compound annual growth rate (CAGR) of XX% from 2024 to 2031. • Asia Pacific held the major market of more than XX% of the global revenue with a market size of USD XX million in 2024 and will grow at a compound annual growth rate (CAGR) of XX% from 2024 to 2031. • Latin America's market will have more than XX% of the global revenue with a market size of USD XX million in 2024 and will grow at a compound annual growth rate (CAGR) of XX% from 2024 to 2031. • Middle East and Africa held the major market of around XX% of the global revenue with a market size of USD XX million in 2024 and will grow at a compound annual growth rate (CAGR) of XX% from 2024 to 2031. • According to Cognitive Market Research, Progestogens is the dominant therapeutic segment for the cancer cachexia market. • According to Cognitive Market Research, Appetite Stimulators is the dominant mechanism action segment for the cancer cachexia market.

MARKET DYNAMICS:

Key Drivers

Increase in the incidence of cancer fuels the demand for Cancer Cachexia Treatment

One of the key drivers behind the significant growth in cancer cachexia treatment is the rising prevalence of cancer globally. As cancer rates continue to increase, particularly in aging populations, the demand for effective cachexia management strategies grows accordingly. For instance. For instance, The International Agency Research on Cancer- Globocan 2020 report states that out of 19,292,789 new cancer cases recognized worldwide in 2020, 9,958,133 deaths were attributed to cancer. There will be 50,550,287 cancer cases worldwide in the next five years, according to forecasts. By 2040, 28,887,940 new cases of cancer are expected worldwide. (Source:https://www.uicc.org/news/globocan-2020-global-cancer-data) Furthermore, according to GLOBOCAN 2020, 495,773 pancreatic, 604,100 esophageal, 1,414,259 prostate, and 1,148,515 colon cancer cases were identified worldwide in 2020, accounting for 2,206771 new cancer cases. Cachexia is very common in patients with the cancer types listed above, so over the next few years, there will be a growing need for cancer cachexia treatment. Thus, the increase in cancer incidence surges demand for advanced therapeutics drugs, which drives the growth of cancer cachexia market.

Key Restrain

The stringent government policies and high cost associated with the treatment hampers Cancer Cachexia market growth

The stringent government policies and the high costs associated with the treatment presents a significant barrier to the growth of the market. Since terminally sick cancer patients are more likely to experience cancer cachexia, yet medications used to treat this disorder typically have to closely follow the same guidelines as other cancer medications. Many countries have lengthy approval processes for pharmaceuticals, particularly those connected to cancer, due to strict regulatory standards. The amount of time needed for countries to approve cancer medications following their current national regulatory criteria varies greatly. For instance, The CHMP in Europe has 210 days to provide its opinion. This is followed by a period of decision-making phase which may extend upto three months. As a result, patients typically acquire access to promising medications (such as those for cancer cachexia) at varying times. This significantly limits the majority of large corporations' capacity marketing ability. Many individuals miss out on potentially necessary treatment that might be utilized to improve their quality of life because cancer cachexia drugs are given to terminally ill patients due to delayed authorization in various nations (Source:https://extranet.who.int/prequal/sites/default/files/document_files/article_58_guidelines.pdf) In addition, the expense of treating cancer patients with cachexia is significantly higher than that of t...

In 2022, Turkey reported a rate of 48 cancer incidents per 100,000 persons per year in the Middle East and North Africa. Morocco, Lebanon, and Tunisia followed with rates between 23 and 26 per 100,000 persons during the same year. Yemen and the United Arab Emirates (UAE) had the lowest crude rate of cancer incidents in the region with 2.5 incidents per 100,000 people.

This statistic depicts cancer incidence rates among women worldwide between 2003 and 2007, per 100,000 inhabitants. White women in the United States had one of the highest figures, with an incidence rate of almost 300 per 100,000 inhabitants.

BackgroundThe 5-year survival rate of cancer patients is the most commonly used statistic to reflect improvements in the war against cancer. This idea, however, was refuted based on an analysis showing that changes in 5-year survival over time bear no relationship with changes in cancer mortality.MethodsHere we show that progress in the fight against cancer can be evaluated by analyzing the association between 5-year survival rates and mortality rates normalized by the incidence (mortality over incidence, MOI). Changes in mortality rates are caused by improved clinical management as well as changing incidence rates, and since the latter can mask the effects of the former, it can also mask the correlation between survival and mortality rates. However, MOI is a more robust quantity and reflects improvements in cancer outcomes by overcoming the masking effect of changing incidence rates. Using population-based statistics for the US and the European Nordic countries, we determined the association of changes in 5-year survival rates and MOI.ResultsWe observed a strong correlation between changes in 5-year survival rates of cancer patients and changes in the MOI for all the countries tested. This finding demonstrates that there is no reason to assume that the improvements in 5-year survival rates are artificial. We obtained consistent results when examining the subset of cancer types whose incidence did not increase, suggesting that over-diagnosis does not obscure the results.ConclusionsWe have demonstrated, via the negative correlation between changes in 5-year survival rates and changes in MOI, that increases in 5-year survival rates reflect real improvements over time made in the clinical management of cancer. Furthermore, we found that increases in 5-year survival rates are not predominantly artificial byproducts of lead-time bias, as implied in the literature. The survival measure alone can therefore be used for a rough approximation of the amount of progress in the clinical management of cancer, but should ideally be used with other measures.

cancer therapeutics and biotherapeutics Market Outlook

According to our latest research, the global cancer therapeutics and biotherapeutics market size stood at USD 195.8 billion in 2024, reflecting robust demand and innovation in oncology treatments. The market is projected to expand at a CAGR of 8.7% from 2025 to 2033, reaching an estimated USD 418.7 billion by 2033. This impressive growth is driven by the increasing incidence of cancer worldwide, rapid advancements in biotherapeutic modalities, and the ongoing introduction of novel, targeted therapies that enhance patient outcomes.

A key growth factor for the cancer therapeutics and biotherapeutics market is the rising global cancer burden. According to the World Health Organization, cancer remains one of the leading causes of morbidity and mortality worldwide, with over 20 million new cases and 10 million deaths in 2024. The aging population, lifestyle changes, environmental factors, and improved diagnostic capabilities are contributing to the escalating prevalence of various cancer types. This has led to a heightened demand for innovative and effective therapeutic solutions, spurring investments in research and development by both public and private entities. In particular, the emergence of precision medicine and personalized therapies has revolutionized cancer care, offering hope for improved survival rates and quality of life for patients.

Another significant driver is the rapid advancement and adoption of biotherapeutics, such as monoclonal antibodies, immune checkpoint inhibitors, and cell therapies. These modalities have demonstrated superior efficacy and safety profiles compared to traditional chemotherapies, leading to their widespread adoption in clinical practice. Pharmaceutical and biotechnology companies are increasingly focusing on the development of next-generation biotherapeutics, leveraging cutting-edge technologies like CRISPR, CAR-T, and bispecific antibodies. The expanding pipeline of innovative drugs, coupled with expedited regulatory approvals and favorable reimbursement policies in key markets, is accelerating the commercialization of novel cancer therapies and broadening patient access to life-saving treatments.

Furthermore, the integration of artificial intelligence, big data analytics, and digital health tools is transforming the landscape of cancer therapeutics and biotherapeutics. These technologies are enabling more accurate tumor profiling, better patient stratification, and optimized treatment regimens, ultimately leading to improved clinical outcomes. Collaborations between academic institutions, research organizations, and industry stakeholders are fostering a vibrant ecosystem for oncology innovation. Additionally, growing awareness among patients and healthcare providers about the benefits of targeted and immunotherapeutic approaches is driving uptake and supporting market expansion. The convergence of scientific breakthroughs, supportive policy frameworks, and patient-centric care models is expected to sustain the robust growth trajectory of the cancer therapeutics and biotherapeutics market over the forecast period.

Regionally, North America remains the dominant market, accounting for the largest share in 2024, followed by Europe and Asia Pacific. The United States, in particular, benefits from a well-established healthcare infrastructure, strong R&D capabilities, and high healthcare expenditure. However, the Asia Pacific region is witnessing the fastest growth, fueled by rising cancer incidence, increasing healthcare investments, and expanding access to advanced therapies in countries like China, Japan, and India. Europe continues to play a pivotal role, driven by supportive regulatory environments and active participation in global oncology research initiatives. Latin America and the Middle East & Africa are gradually emerging as promising markets, supported by improving healthcare access and growing awareness about cancer therapies.

Product Type Analysis

The cancer therapeutics and biother

The Synthetic Colorectal Cancer Global Dataset is a fully anonymised, high-dimensional synthetic dataset designed for global cancer research, predictive modelling, and educational use. It encompasses demographic, clinical, lifestyle, genetic, and healthcare access factors relevant to colorectal cancer incidence, outcomes, and survivability.

Dataset Features

• Patient_ID: Unique identifier for each patient.
• Country: Patient's country of residence.
• Age: Age at diagnosis (in years).
• Gender: Biological sex of the patient (Male/Female/Other).
• Cancer_Stage: Stage of colorectal cancer at diagnosis (e.g., Stage I–IV).
• Tumor_Size_mm: Size of the tumor in millimeters.
• Family_History: Presence of colorectal cancer in family history (True/False).
• Smoking_History: Smoking behavior or history (e.g., Current, Former, Never).
• Alcohol_Consumption: Level of alcohol consumption (e.g., High, Moderate, None).
• Obesity_BMI: BMI classification related to obesity.
• Diet_Risk: Diet-related cancer risk (e.g., High Fat, Low Fiber).
• Physical_Activity: Level of physical activity (e.g., Sedentary, Active).
• Diabetes: Diabetes diagnosis (True/False).
• Inflammatory_Bowel_Disease: Presence of IBD (True/False).
• Genetic_Mutation: Genetic mutations relevant to colorectal cancer (e.g., APC, KRAS).
• Screening_History: History of cancer screenings (True/False).
• Early_Detection: Whether cancer was detected early (True/False).
• Treatment_Type: Primary treatment type (e.g., Surgery, Chemotherapy, Radiation).
• Survival_5_years: 5-year survival status (True/False).
• Mortality: Mortality outcome (Alive/Deceased).
• Healthcare_Costs: Estimated treatment costs (in USD).
• Incidence_Rate_per_100K: Country-level incidence rate per 100,000 people.
• Mortality_Rate_per_100K: Country-level mortality rate per 100,000 people.
• Urban_or_Rural: Patient's living area (Urban/Rural).
• Economic_Classification: Country's economic level (e.g., Low, Middle, High income).
• Healthcare_Access: Access level to healthcare services (e.g., Good, Limited).
• Insurance_Status: Insurance coverage status (Insured/Uninsured).
• Survival_Prediction: Model-derived survival prediction (probability or binary).

Distribution

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Usage

This dataset can be used for:

• Global Cancer Research: Analyze how clinical, lifestyle, and socioeconomic factors affect colorectal cancer outcomes worldwide.
• Predictive Modeling: Develop models to estimate survival probability or treatment outcomes.
• Healthcare Policy Analysis: Study disparities in healthcare access and outcomes across countries.
• Educational Use: Support training in epidemiology, oncology, public health, and machine learning.

Coverage

The dataset includes 100% synthetic yet clinically plausible records from diverse countries and demographic groups. It is anonymized and modeled to reflect real-world variability in risk factors, diagnosis stages, treatment, and survival without compromising patient privacy.

License

CC0 (Public Domain)

Who Can Use It

• Epidemiologists and Medical Researchers: To explore global patterns in colorectal cancer.
• Public Health Experts and Policymakers: For assessing equity in healthcare access and cancer outcomes.
• Data Scientists and Educators: As a rich dataset for teaching data analysis, classification, regression, and health informatics.

BackgroundLiver cancer due to hepatitis C (LCDHC) is one of the leading causes of cancer-related deaths worldwide, and the burden of LCDHC is increasing. We aimed to report the burden of LCDHC at the global, regional, and national levels in 204 countries from 1990 to 2019, stratified by etiology, sex, age, and Sociodemographic Index.MethodsData on LCDHC were available from the Global Burden of Disease, Injuries, and Risk Factors (GBD) study 2019. Numbers and age-standardized mortality, incidence, and disability-adjusted life year (DALY) rates per 100,000 population were estimated through a systematic analysis of modeled data from the GBD 2019 study. The trends in the LCDHC burden were assessed using the annual percentage change.ResultsGlobally, in 2019, there were 152,225 new cases, 141,810 deaths, and 2,878,024 DALYs due to LCDHC. From 1990 to 2019, the number of incidences, mortality, and DALY cases increased by 80.68%, 67.50%, and 37.20%, respectively. However, the age-standardized incidence, mortality, and DALY rate had a decreasing trend during this period. In 2019, the highest age-standardized incidence rates (ASIRs) of LCDHC were found in high-income Asia Pacific, North Africa and the Middle East, and Central Asia. At the regional level, Mongolia, Egypt, and Japan had the three highest ASIRs in 2019. The incidence rates of LCDHC were higher in men and increased with age, with a peak incidence in the 95+ age group for women and the 85–89 age group for men in 2019. A nonlinear association was found between the age-standardized rates of LCDHC and sociodemographic index values at the regional and national levels.ConclusionsAlthough the age-standardized rates of LCDHC have decreased, the absolute numbers of incident cases, deaths, and DALYs have increased, indicating that LCDHC remains a significant global burden. In addition, the burden of LCDHC varies geographically. Male and older adult/s individuals have a higher burden of LCDHC. Our findings provide insight into the global burden trend of LCDHC. Policymakers should establish appropriate methods to achieve the HCV elimination target by 2030 and reducing the burden of LCDHC.

In 2022, Uruguay had the highest age-standardized prevalence rate of all cancer types in Latin America and the Caribbean, with 1,316 cases per 100,000 population. Barbados and Cuba followed, with cancer prevalence rates of 1,192.3 and 1,114.8, respectively. That year, Uruguay also had the region's highest mortality death rate.

In a recent report it was shown that the U.S. has the highest prevalence of diagnosed cancer cases among all adults, with around 9 percent of the adult population having some cancer diagnosis. Cancer is the second leading cause of death from chronic diseases worldwide after cardiovascular diseases.

Global cancer risks

Globally, cancer accounts for about 1 in every 6 deaths. Many cancer cases are caused by behavioral and dietary risks including tobacco, alcohol and physical inactivity. The prevalence of tobacco smoking is on the decline and is expected to decline further in the future. Smoking has been linked to lung cancer, other upper respiratory cancers and chronic obstructive pulmonary disease (COPD). Among other cancer risk factors, alcohol consumption has been linked to liver and colorectal cancers, as well as other non-communicable diseases. Many European countries have high rates of alcohol consumption.

Global cancer prevalence

Globally, trachea, bronchus and lung cancers are responsible for the most cancer deaths, followed by liver cancer. Lifestyle modification is one of the easiest ways people can reduce their risk of these types of cancer. Among all cancer patients globally, a majority had a history of alcohol consumption. Similarly, in China, EU5 and Russia, over a quarter of all cancer patients had a history of smoking.

BackgroundDespite rising incidence and mortality rates in Africa, cancer has been given low priority in the research field and in healthcare services. Indeed, 57% of all new cancer cases around the world occur in low income countries exacerbated by lack of awareness, lack of preventive strategies, and increased life expectancies. Despite recent efforts devoted to cancer epidemiology, statistics on cancer rates in Africa are often dispersed across different registries. In this study our goal included identifying the most promising prevention and treatment approaches available in Africa. To do this, we collated and analyzed the incidence and fatality rates for the 10 most common and fatal cancers in 56 African countries grouped into 5 different regions (North, West, East, Central and South) over 16-years (2002–2018). We examined temporal and regional trends by investigating the most important risk factors associated to each cancer type. Data were analyzed by cancer type, African region, gender, measures of socioeconomic status and the availability of medical devices.ResultsWe observed that Northern and Southern Africa were most similar in their cancer incidences and fatality rates compared to other African regions. The most prevalent cancers are breast, bladder and liver cancers in Northern Africa; prostate, lung and colorectal cancers in Southern Africa; and esophageal and cervical cancer in East Africa. In Southern Africa, fatality rates from prostate cancer and cervical cancer have increased. In addition, these three cancers are less fatal in Northern and Southern Africa compared to other regions, which correlates with the Human Development Index and the availability of medical devices. With the exception of thyroid cancer, all other cancers have higher incidences in males than females.ConclusionOur results show that the African continent suffers from a shortage of medical equipment, research resources and epidemiological expertise. While recognizing that risk factors are interconnected, we focused on risk factors more or less specific to each cancer type. This helps identify specific preventive and therapeutic options in Africa. We see a need for implementing more accurate preventive strategies to tackle this disease as many cases are likely preventable. Opportunities exist for vaccination programs for cervical and liver cancer, genetic testing and use of new targeted therapies for breast and prostate cancer, and positive changes in lifestyle for lung, colorectal and bladder cancers. Such recommendations should be tailored for the different African regions depending on their disease profiles and specific needs.

In 2022, Turkey had the highest cumulative risk factor for respiratory cancer deaths before the age of 75 by far in the Middle East and North Africa, at 4.4 percent. This was nearly twice the rate of Gaza and the West Bank, which had the second highest risk factor at 2.3 percent.