Users can access data about cancer statistics in the United States including but not limited to searches by type of cancer and race, sex, ethnicity, age at diagnosis, and age at death. Background Surveillance Epidemiology and End Results (SEER) database’s mission is to provide information on cancer statistics to help reduce the burden of disease in the U.S. population. The SEER database is a project to the National Cancer Institute. The SEER database collects information on incidence, prevalence, and survival from specific geographic areas representing 28 percent of the United States population. User functionality Users can access a variety of reso urces. Cancer Stat Fact Sheets allow users to look at summaries of statistics by major cancer type. Cancer Statistic Reviews are available from 1975-2008 in table format. Users are also able to build their own tables and graphs using Fast Stats. The Cancer Query system provides more flexibility and a larger set of cancer statistics than F ast Stats but requires more input from the user. State Cancer Profiles include dynamic maps and graphs enabling the investigation of cancer trends at the county, state, and national levels. SEER research data files and SEER*Stat software are available to download through your Internet connection (SEER*Stat’s client-server mode) or via discs shipped directly to you. A signed data agreement form is required to access the SEER data Data Notes Data is available in different formats depending on which type of data is accessed. Some data is available in table, PDF, and html formats. Detailed information about the data is available under “Data Documentation and Variable Recodes”.

List of Top Disciplines of Cancer Research Statistics and Treatment sorted by citations.

Cloud based data science infrastructure that provides secure access to cancer research data from NCI programs and key external cancer programs. Serves as coordinated resource for public data sharing of NCI funded programs. Users can explore and use analytical and visualization tools for data analysis. Enables to search and aggregate data across repositories including Cancer Data Service, Clinical Trial Data Commons, Genomic Data Commons, Imaging Data Commons, Integrated Canine Data Commons, Proteomic Data Commons.

The United States Cancer Statistics (USCS) online databases in WONDER provide cancer incidence and mortality data for the United States for the years since 1999, by year, state and metropolitan areas (MSA), age group, race, ethnicity, sex, childhood cancer classifications and cancer site. Report case counts, deaths, crude and age-adjusted incidence and death rates, and 95% confidence intervals for rates. The USCS data are the official federal statistics on cancer incidence from registries having high-quality data and cancer mortality statistics for 50 states and the District of Columbia. USCS are produced by the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI), in collaboration with the North American Association of Central Cancer Registries (NAACCR). Mortality data are provided by the Centers for Disease Control and Prevention (CDC), National Center for Health Statistics (NCHS), National Vital Statistics System (NVSS).

Background Disruption of the balance between apoptosis and proliferation is considered to be an important factor in the development and progression of tumours. In the present study we determined the in vivo cell kinetics along the spectrum of apparently normal epithelium, hyperplasia, preinvasive lesions and invasive carcinoma, in breast tissues affected by fibrocystic changes in which preinvasive and/or invasive lesions developed, as a model of breast carcinogenesis. Materials and methods A total of 32 areas of apparently normal epithelium and 135 ductal proliferative and neoplastic lesions were studied. More than one epithelial lesion per case were analyzed. The apoptotic index (AI) and the proliferative index (PI) were expressed as the percentage of TdT-mediated dUTP-nick end-labelling (TUNEL) and Ki-67-positive cells, respectively. The PI/AI (P/A index) was calculated for each case. Results The AIs and PIs were significantly higher in hyperplasia than in apparently normal epithelium (P = 0.04 and P = 0.0005, respectively), in atypical hyperplasia than in hyperplasia (P = 0.01 and P = 0.04, respectively) and in invasive carcinoma than in in situ carcinoma (P < 0.001 and P < 0.001, respectively). The two indices were similar in atypical hyperplasia and in in situ carcinoma. The P/A index increased significantly from normal epithelium to hyperplasia (P = 0.01) and from preinvasive lesions to invasive carcinoma (P = 0.04) whereas it was decreased (non-significantly) from hyperplasia to preinvasive lesions. A strong positive correlation between the AIs and the PIs was found (r = 0.83, P < 0.001). Conclusion These findings suggest accelerating cell turnover along the continuum of breast carcinogenesis. Atypical hyperplasias and in situ carcinomas might be kinetically similar lesions. In the transition from normal epithelium to hyperplasia and from preinvasive lesions to invasive carcinoma the net growth of epithelial cells results from a growth imbalance in favour of proliferation. In the transition from hyperplasia to preinvasive lesions there is an imbalance in favour of apoptosis.

Research dataset and analysis for Cancer Treatment including statistics, forecasts, and market insights

In the following maps, the U.S. states are divided into groups based on the rates at which people developed or died from cancer in 2013, the most recent year for which incidence data are available.

The rates are the numbers out of 100,000 people who developed or died from cancer each year.

Incidence Rates by State The number of people who get cancer is called cancer incidence. In the United States, the rate of getting cancer varies from state to state.

*Rates are per 100,000 and are age-adjusted to the 2000 U.S. standard population.

‡Rates are not shown if the state did not meet USCS publication criteria or if the state did not submit data to CDC.

†Source: U.S. Cancer Statistics Working Group. United States Cancer Statistics: 1999–2013 Incidence and Mortality Web-based Report. Atlanta (GA): Department of Health and Human Services, Centers for Disease Control and Prevention, and National Cancer Institute; 2016. Available at: http://www.cdc.gov/uscs.

Death Rates by State Rates of dying from cancer also vary from state to state.

*Rates are per 100,000 and are age-adjusted to the 2000 U.S. standard population.

†Source: U.S. Cancer Statistics Working Group. United States Cancer Statistics: 1999–2013 Incidence and Mortality Web-based Report. Atlanta (GA): Department of Health and Human Services, Centers for Disease Control and Prevention, and National Cancer Institute; 2016. Available at: http://www.cdc.gov/uscs.

Source: https://www.cdc.gov/cancer/dcpc/data/state.htm

List of Top Schools of Cancer Research Statistics and Treatment sorted by citations.

Age-standardised rate of mortality from oral cancer (ICD-10 codes C00-C14) in persons of all ages and sexes per 100,000 population.RationaleOver the last decade in the UK (between 2003-2005 and 2012-2014), oral cancer mortality rates have increased by 20% for males and 19% for females1Five year survival rates are 56%. Most oral cancers are triggered by tobacco and alcohol, which together account for 75% of cases2. Cigarette smoking is associated with an increased risk of the more common forms of oral cancer. The risk among cigarette smokers is estimated to be 10 times that for non-smokers. More intense use of tobacco increases the risk, while ceasing to smoke for 10 years or more reduces it to almost the same as that of non-smokers3. Oral cancer mortality rates can be used in conjunction with registration data to inform service planning as well as comparing survival rates across areas of England to assess the impact of public health prevention policies such as smoking cessation.References:(1) Cancer Research Campaign. Cancer Statistics: Oral – UK. London: CRC, 2000.(2) Blot WJ, McLaughlin JK, Winn DM et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988; 48: 3282-7. (3) La Vecchia C, Tavani A, Franceschi S et al. Epidemiology and prevention of oral cancer. Oral Oncology 1997; 33: 302-12.Definition of numeratorAll cancer mortality for lip, oral cavity and pharynx (ICD-10 C00-C14) in the respective calendar years aggregated into quinary age bands (0-4, 5-9,…, 85-89, 90+). This does not include secondary cancers or recurrences. Data are reported according to the calendar year in which the cancer was diagnosed.Counts of deaths for years up to and including 2019 have been adjusted where needed to take account of the MUSE ICD-10 coding change introduced in 2020. Detailed guidance on the MUSE implementation is available at: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/articles/causeofdeathcodinginmortalitystatisticssoftwarechanges/january2020Counts of deaths for years up to and including 2013 have been double adjusted by applying comparability ratios from both the IRIS coding change and the MUSE coding change where needed to take account of both the MUSE ICD-10 coding change and the IRIS ICD-10 coding change introduced in 2014. The detailed guidance on the IRIS implementation is available at: https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/impactoftheimplementationofirissoftwareforicd10causeofdeathcodingonmortalitystatisticsenglandandwales/2014-08-08Counts of deaths for years up to and including 2010 have been triple adjusted by applying comparability ratios from the 2011 coding change, the IRIS coding change and the MUSE coding change where needed to take account of the MUSE ICD-10 coding change, the IRIS ICD-10 coding change and the ICD-10 coding change introduced in 2011. The detailed guidance on the 2011 implementation is available at https://webarchive.nationalarchives.gov.uk/ukgwa/20160108084125/http://www.ons.gov.uk/ons/guide-method/classifications/international-standard-classifications/icd-10-for-mortality/comparability-ratios/index.htmlDefinition of denominatorPopulation-years (aggregated populations for the three years) for people of all ages, aggregated into quinary age bands (0-4, 5-9, …, 85-89, 90+)

Financial overview and grant giving statistics of Cancer Research and Biostatistics

Financial overview and grant giving statistics of American Association for Cancer Research

The relative distribution and prevalence of cancer cases by type in the All of Us Research Program from self-reported survey data and electronic health record overall.

Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer (MBC) in the United Kingdom is not known, and the importance of these genes in the increased risk of female breast cancer associated with a family history of breast cancer in a male first-degree relative is unclear. Methods We have carried out a population-based study of 94 MBC cases collected in the UK. We screened genomic DNA for mutations in BRCA1 and BRCA2 and used family history data from these cases to calculate the risk of breast cancer to female relatives of MBC cases. We also estimated the contribution of BRCA1 and BRCA2 to this risk. Results Nineteen cases (20%) reported a first-degree relative with breast cancer, of whom seven also had an affected second-degree relative. The breast cancer risk in female first-degree relatives was 2.4 times (95% confidence interval [CI] = 1.4–4.0) the risk in the general population. No BRCA1 mutation carriers were identified and five cases were found to carry a mutation in BRCA2. Allowing for a mutation detection sensitivity frequency of 70%, the carrier frequency for BRCA2 mutations was 8% (95% CI = 3–19). All the mutation carriers had a family history of breast, ovarian, prostate or pancreatic cancer. However, BRCA2 accounted for only 15% of the excess familial risk of breast cancer in female first-degree relatives. Conclusion These data suggest that other genes that confer an increased risk for both female and male breast cancer have yet to be found.

Context

This data comes from aggregation of the tables available on the NIH's National Cancer Institutes State Cancer Profiles, specifically with their incidence tables.

The objective of the State Cancer Profiles Web site is to provide a system to characterize the cancer burden in a standardized manner in order to motivate action, integrate surveillance into cancer control planning, characterize areas and demographic groups, and expose health disparities. The focus is on cancer sites for which there are evidence based control interventions. Interactive graphics and maps provide visual support for deciding where to focus cancer control efforts.

Content

This data has cancer Incidence rates broken down by US County and includes data aggregated from 2012-2016. It has both incidence rates per 100k as well as yearly totals averaged over that period

Potential Future Work

This data is summarized across other potentially illuminating fields. The State Cancer Profiles can be further broken down by cancer area, race/ethnicity, sex, age, and stage. If more fidelity on the data would be helpful please add it to the discussion section and I can work on adding it!

Data Use Restrictions

Read Carefully Before Using

By using these data, you signify your agreement to comply with the following statutorily based requirements.

The Public Health Service Act (42 U.S.C. 242m(d)) provides that the data collected by the National Center for Health Statistics (NCHS) may be used only for the purpose for which they were obtained; any effort to determine the identity of any reported cases, or to use the information for any purpose other than for statistical reporting and analysis, is against the law. The National Program of Cancer Registries (NPCR), Centers for Disease Control and Prevention (CDC), has obtained an assurance of confidentiality pursuant to Section 308(d) of the Public Health Service Act, 42 U.S.C. 242m(d). This assurance provides that identifiable or potentially identifiable data collected by the NPCR may be used only for the purpose for which they were obtained unless the person or establishment from which they were obtained has consented to such use. Any effort to determine the identity of any reported cases, or to use the information for any purpose other than statistical reporting and analysis, is a violation of the assurance.

Therefore users will: - Use the data for statistical reporting and analysis only. - Make no attempt to learn the identity of any person or establishment included in these data. - Make no disclosure or other use of the identity of any person or establishment discovered inadvertently, and advise the appropriate contact for the data provider. In addition to immediately notifying "Contact Us" of the potential disclosure, - For mortality data, notify the Confidentiality Officer at the National Center for Health Statistics (Alvan O. Zarate, Ph.D.), 3311 Toledo Road, Rm 7116, Hyattsville, MD 20782, Phone: 301-458-4601, Fax: 301-458-4021) - For incidence data notify both the Federal agency that provided the data and notify the relevant state or metropolitan area cancer registryExternal Web Site Policy, of any such discovery. - For CDC's National Program of Cancer Registries (NPCR) areas, notify the Associate Director for Science, Office of Science Policy and Technology Transfer, CDC, Mailstop D-50, 1600 Clifton Road, N.E., Atlanta, Georgia, 30333, Phone: 404-639-7240) - For NCI's Surveillance, Epidemiology, and End Results (SEER) Program registry areas, notify the Branch Chief of the Cancer Statistics Branch of the Surveillance Research Program, Division of Cancer Control and Population Sciences, NCI, BG 9609 MSC 9760, 9609 Medical Center Drive, Bethesda, MD 20892-9760, Phone: 301-496-8510, Fax: 301-496-9949.

Project Title: Cancer Data Analysis for Improved Healthcare

Description:

Our Cancer Data Analysis project is a comprehensive effort aimed at harnessing the power of data to advance our understanding of cancer, improve patient care, and contribute to ongoing research in oncology. This project brings together a multidisciplinary team of researchers, data scientists, and healthcare professionals committed to making a positive impact on the fight against cancer.

Project Objectives:

Data Collection: We have compiled a diverse and extensive dataset containing information on cancer incidence, patient demographics, treatment outcomes, genomic profiles, and more. This dataset represents a valuable resource for researchers and healthcare providers.

Insights and Trends: Through advanced data analysis techniques, we aim to uncover meaningful insights into cancer trends, including the prevalence of different cancer types, regional variations, and changes over time. These insights can inform healthcare policies and resource allocation.

Treatment Optimization: By analyzing treatment outcomes and patient responses to various therapies, we aim to identify patterns that can help tailor cancer treatment plans to individual patient needs, ultimately improving survival rates and quality of life.

Epidemiological Insights: We analyze epidemiological data to track the spread of cancer

Impact:

The Cancer Data Analysis project aspires to make a significant impact on cancer research, clinical practice, and public health initiatives. By providing valuable data and insights, we hope to contribute to:

Early cancer detection and diagnosis Improved treatment protocols Enhanced patient care and support Informed healthcare policy decisions Accelerated research breakthroughs

Collaboration:

We welcome collaboration with fellow researchers, healthcare professionals, and organizations committed to the fight against cancer. Together, we can leverage data-driven approaches to drive positive change in the field of oncology.

Join us in our mission to combat cancer through data-driven insights and innovative solutions. Together, we can make a difference in the lives of cancer patients and their families.

This submission includes publicly available data extracted in its original form. Please reference the Related Publication listed here for source and citation information "The United States Cancer Statistics (USCS) are the official federal statistics on cancer incidence from registries having high-quality data and cancer mortality statistics for 50 states and the District of Columbia. USCS are produced by the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI)." [Quote from: https://wonder.cdc.gov/cancer.htm]>

Imaging Data Commons (IDC) is a repository within the Cancer Research Data Commons (CRDC) that manages imaging data and enables its integration with the other components of CRDC. IDC hosts a growing number of imaging collections that are contributed by either funded US National Cancer Institute (NCI) data collection activities, or by the individual researchers.Image data hosted by IDC is stored in DICOM format.

SEER Limited-Use cancer incidence data with associated population data. Geographic areas available are county and SEER registry. The Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute collects and distributes high quality, comprehensive cancer data from a number of population-based cancer registries. Data include patient demographics, primary tumor site, morphology, stage at diagnosis, first course of treatment, and follow-up for vital status. The SEER Program is the only comprehensive source of population-based information in the United States that includes stage of cancer at the time of diagnosis and survival rates within each stage.

This database of cancer-related citations for publications authored by CDC’s Division of Cancer Prevention and Control (DCPC) staff, fosters collaboration among scientists throughout the world. Allows for searching for links to scientific articles authored or co-authored by researchers from DCPC since 2000.

This blog post was posted by Rob Rivers on August 12, 2014.