In 2022, about 17.3 percent of the American population was 65 years old or over; an increase from the last few years and a figure which is expected to reach 22 percent by 2050. This is a significant increase from 1950, when only eight percent of the population was 65 or over.

A rapidly aging population

In recent years, the aging population of the United States has come into focus as a cause for concern, as the nature of work and retirement is expected to change in order to keep up. If a population is expected to live longer than the generations before, the economy will have to change as well in order to fulfill the needs of the citizens. In addition, the birth rate in the U.S. has been falling over the last 20 years, meaning that there are not as many young people to replace the individuals leaving the workforce.

The future population

It’s not only the American population that is aging -- the global population is, too. By 2025, the median age of the global workforce is expected to be 39.6 years, up from 33.8 years in 1990. Additionally, it is projected that there will be over three million people worldwide aged 100 years and over by 2050.

Author: Michael Robinson, educatorGrade/Audience: high school, ap human geography, professional developmentResource type: lessonSubject topic(s): population, human geographyRegion: asiaStandards: AP Human Geography Connection 2.9 Aging Populations - Explain the causes and consequences of an aging population. An aging population has political, social, and economic consequences, including the dependency ratio. Objectives: The student will identify the leading causes of death in South Korea. The student will describe the growing aging population in South Korea. The student will explain how South Korea is dealing with the aging population. The student will describe and explain possible ways of supporting the growing elderly population in South Korea. Summary: South Korea has one of the highest life expectancies in the world, which has led to a growing aged population. The number of persons over 65 is projected to continue to rise, and with the increase there are social issues the government must address. The lesson has students analyzing graphs and maps from The Atlas of Korea to identity, describe, and explain aging of the population of South Korea. Students will listen to a news report and read an editorial to help them determine solutions to this growing problem in South Korea.

Over the last decade, Japan’s population has aged more and more, to the point where more than a quarter of Japanese were 65 years and older in 2022. Population growth has stopped and even reversed, since it’s been in the red for several years now.

It’s getting old

With almost 30 percent of its population being elderly inhabitants, Japan is considered the “oldest” country in the world today. Japan boasts a high life expectancy, in fact, the Japanese tend to live longer than the average human worldwide. The increase of the aging population is accompanied by a decrease of the total population caused by a sinking birth rate. Japan’s fertility rate has been below the replacement rate for many decades now, mostly due to economic uncertainty and thus a decreasing number of marriages.

Are the Japanese invincible?

There is no real mystery surrounding the ripe old age of so many Japanese. Their high average age is very likely due to high healthcare standards, nutrition, and an overall high standard of living – all of which could be adopted by other industrial nations as well. But with high age comes less capacity, and Japan’s future enemy might not be an early death, but rather a struggling social network.

According to the most recent population forecasts for Switzerland (Bundesamt für Statistik 2015), the share of old-age dependants (older than 65 years) relative to the working age population (20-64) is going to increase from 29.1% in 2015 to 48.1% in 2045. In the same time span, total population is expected to grow from 8.3 million to 10.2 million while the potential workforce is growing from 4.8 million to 5.3 million. As a result, potential labour supply per capita is decreasing and at the same time the share of old-age dependants as well as the average age of the population are increasing rapidly. Among other problems, this is going to lead to significant distortions on labour markets; such as labour shortages or shifts in the structure of labour demand due to shifts in final goods demand. Furthermore, the current political climate in Switzerland tends towards restricting immigration. Since the Swiss economy already relies heavily on foreign workers, a restriction of immigration might aggravate the predicted labour supply shortages even further.

The goal of this research project is to evaluate the consequences of population ageing for the Swiss labour market. A special focus lies on the labour demand side, specifically on medium and long term sectoral and occupational shifts caused by a decrease in (skilled) labour supply and a change in consumer demand structure due to the demographic change. Moreover, the general equilibrium effects of different policy reforms will be evaluated and compared. To achieve this goal we construct a dynamic overlapping generations (OLG) computable general equilibrium (CGE) model of Switzerland and calibrate it with current Swiss data. Models of this type are the conventional approach to evaluating inter- and intra-generational effects of population ageing. However, only few studies focus on the labour market and even fewer emphasise the demand side. The evidence is particularly scarce for Switzerland, where only a handful of general equilibrium analyses relating to population ageing have been conducted.

In order to facilitate estimating realistic parameters of the model as well as calibrating the model to expected short and medium term industry-specific developments we conduct a customised firm level survey, which, on its own, already constitutes a significant contribution to the relevant literature. The finalised model does not only allow us to predict transitional and long-term effects of the demographic change on the economy and the industry structure. It also provides us with the ability to evaluate and compare different reform proposals, such as an increase in the retirement age, reforms of the pension and healthcare systems and different immigration scenarios. As such, we will be able to give recommendations for optimal policy choice and provide valuable inputs to the political debate.

In 2022, malignant neoplasm was the cause of death for 783.9 people per 100,000 population among elderly people in South Korea aged 65 years and older. This made it the leading cause of death for seniors that year, far ahead of other common causes such as cardiovascular disease and COVID-19.

Abstract Introduction: The elderly population has risen sharply in Brazil, increasing the need for a health policy focused on health promotion and disease prevention. Attention should also be focused on functional capacity because of the personal and family suffering caused by dependency, as well as the increased demand placed on public services. Objective: To check the health and functional capacity of elderly residents in a small town with a high population aging rate. Methods: A cross-sectional, analytical and non-probabilistic study was performed of 528 elderly persons aged ≥60 years, of both genders, who were evaluated in their home environment. The variables of interest were general health and functional capacity, assessed by the adapted Katz and Lawton and Brody scales. Data analysis was carried out using descriptive and analytical statistical tools. To assess the association between variables the chi-squared test was used, accepting the hypothesis of dependency of variables with p=0.05. Results: The mean age was 72.24±9.33 years. Functional capacity assessment identified that most of the elderly persons carried out activities of daily living (ADLs) and instrumental activities of daily living (IADL) independently; with percentages of 90% and 83.7%, respectively. A statistically significant association was observed (p=0.001) between reports of falls and functional capacity levels. Conclusion: The results show that the elderly of this municipality are mostly independent in performing their daily tasks, representing successful aging.

In 2023, according to those aged over 65 in the United Kingdom, staff shortages and poor NHS management were the main causes of health service strain. Around a third of respondents also pointed to a lack of capacity and increased demands from an aging population. In comparison, the same survey carried out on young people found they believed the main cause of strain on services was a lack of funding, and put a larger emphasis on the impact of Brexit and government policy.

This paper discusses experimental setups for health monitoring and prognostics of electrolytic capacitors under nominal operation and accelerated aging conditions. Electrolytic capacitors have higher failure rates than other components in electronic systems like power drives, power converters etc. Our current work focuses on developing first-principles-based degradation models for electrolytic capacitors under varying electrical and thermal stress conditions. Prognostics and health management for electronic systems aims to predict the onset of faults, study causes for system degradation, and accurately compute remaining useful life. Accelerated life test methods are often used in prognostics research as a way to model multiple causes and assess the effects of the degradation process through time. It also allows for the identification and study of different failure mechanisms and their relationships under different operating conditions. Experiments are designed for aging of the capacitors such that the degradation pattern induced by the aging can be monitored and analyzed. Experimental setups and data collection methods are presented to demonstrate this approach.

In 2023, the share of the German population aged 65 years and older was 22.3 percent. In general, figures have been growing year after year, which is part of a wider trend of the total population in Germany aging. The indicator provides information on the development of the proportion of the working-age population in the total population.

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Longevity And Anti-Senescence Therapy Market Size 2025-2029

The longevity and anti-senescence therapy market size is forecast to increase by USD 9.43 billion at a CAGR of 5.2% between 2024 and 2029.

The market exhibit significant growth due to the increasing elderly population and advancements in research and development. Small molecules targeting DNA sequencing repair and mitochondrial functions are at the forefront of anti-senescence therapies, with clinical trials underway to assess their safety and efficacy. Strategic collaborations and partnerships between gerontology experts, biotech start-ups, and regulatory bodies are driving innovation in this field. Clinical trials are underway to evaluate their efficacy and safety. However, ethical and safety concerns surrounding hemolytic drug therapy and cell renewal therapies necessitate rigorous testing and regulatory oversight. The future of anti-senescence therapies lies in the successful integration of these advancements into regenerative medicine.

What will be the Size of the Market During the Forecast Period?

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The global market for longevity and anti-senescence therapy, a branch of biotechnology reagents focused on delaying or reversing the aging process, has gained significant attention in the healthcare industry. This field targets age-related diseases, including neurodegenerative disorders, cardiovascular diseases, diabetes, osteoarthritis, cancer, and other chronic conditions. Aging is an intricate process characterized by the deterioration of organ homeostasis and the onset of various age-related diseases. The primary causes of aging are metabolic pathways, free radicals, and programmed cell death. These factors contribute to the development of chronic diseases, such as cardiovascular diseases, Parkinson's disease, and cancer.
Anti-senescence therapy aims to combat these age-related processes by employing various interventions. Calorie restriction, for instance, has shown potential in delaying aging and improving health span. Stem cell therapies offer the possibility of regeneration and repair, while targeting specific metabolic pathways can help mitigate the effects of oxidative stress and free radicals. The anti-senescence therapy market is driven by the increasing prevalence of age-related diseases and the growing demand for effective treatments. According to the World Health Organization, chronic diseases account for 71% of all deaths worldwide. As the global population ages, the need for innovative solutions to address these conditions becomes increasingly urgent.

How is this market segmented and which is the largest segment?

The market research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in 'USD billion' for the period 2025-2029, as well as historical data from 2019-2023 for the following segments.

Therapy

  Gene therapy
  Immunotherapy
  Senolytic drug therapy


Application

  Cancer
  Others


Geography

  North America

    Canada
    US


  Europe

    Germany
    UK
    France


  Asia

    China
    India
    Japan
    South Korea


  Rest of World (ROW)

By Therapy Insights

The gene therapy segment is estimated to witness significant growth during the forecast period.

Gene therapy represents a pioneering method within the United States anti-aging and anti-senescence therapy market, focusing on the modification or correction of genes associated with aging and age-related health issues. This advanced therapy utilizes molecular techniques to directly manipulate genetic material, thereby improving cellular functions and potentially reversing or slowing down the aging process. Gene therapy holds immense potential in combating a broad spectrum of age-related conditions, including neurodegenerative diseases, cardiovascular disorders, and specific types of cancer.

Pharmacological therapies and lifestyle-related interventions are essential components of geriatric medicine. However, the emerging field of geroscience, which focuses on the biology of aging, is gaining significant traction in the anti-senescence therapy market. Molecular therapies, including gene therapy, genetic and epigenetic approaches, and cellular therapies, are at the forefront of this innovative field. Gene therapy, in particular, offers a promising solution to address the underlying causes of aging and age-related diseases. Anti-senescence therapy encompasses a range of interventions aimed at delaying or reversing the aging process. Gene therapy, with its ability to modify genes directly, represents a cutting-edge approach in this domain. By targeting genes linked to aging and age-related diseases, gene therapy holds the potential to enhance cellular functions and potentially reverse or decelerate the aging process. This therapy is particularly promising in addressing conditions such as neurodegen

Estimates of the multilevel multinomial logistic regression models for one existing condition versus none†.

This table contains 47094 series, with data for years 2001 - 2001 (not all combinations necessarily have data for all years). This table contains data described by the following dimensions (Not all combinations are available): Geography (167 items: Canada; Newfoundland and Labrador; Health and Community Services Eastern Region; Newfoundland and Labrador; Health and Community Services St. John's Region; Newfoundland and Labrador ...), Sex (3 items: Both sexes; Males; Females ...), Selected causes of death (ICD-10) (17 items: Total; all causes of death; All malignant neoplasms (cancers);Lung cancer; Colorectal cancer ...), Characteristics (6 items: Low 95% confidence interval; number of potential years of life lost; Potential years of life lost; High 95% confidence interval; number of potential years of life lost; Number of potential years of life lost ...).

Understanding the ageing mechanisms of electronic components critical avionics systems such as the GPS and INAV are of critical importance. Electrolytic capacitors and MOSFET’s have higher failure rates among the components of DC-DC power converter systems. Our current work focuses on analyzing and modeling electrolytic capacitor degradation and its effects on the output of DC-DC converter systems. The output degrada- tion is typically measured by an increase in ESR (Equivalent Series Resistance) and decrease in the capacitance value over long periods of use even under nominal operating conditions. Typically the primary effect of degradation is increased ripple current and this has adverse effects on downstream components. For example, in avionics systems where the power supply drives a GPS unit, ripple currents can cause glitches in the GPS position and velocity output, and this may cause errors in the Inertial Navigation (INAV) system, causing the aircraft to fly off course. In this paper, we present the details of our ageing methodology along with details of experiments and analysis of the results.

Aged micro(nano)plastics (MNPs) are normally the ultimate state of plastics in the environment after aging. The changes in the physical and chemical characteristics of aged MNPs significantly influence their environmental behavior by releasing additives, forming byproducts, and adsorbing contaminants. However, a systematic review is lacking on the effects of aged MNPs on ecological and human health regarding the increasing but scattered studies and results. This Review first summarizes the unique characteristics of aged MNPs and methods for quantifying their aging degree. Then we focused on the potential impacts on organisms, ecosystems, and human health, including the “Trojan horse” under real environmental conditions. Through combining meta-analysis and analytic hierarchy process (AHP) model, we demonstrated that, compared to virgin MNPs, aged MNPs would result in biomass decrease and oxidative stress increase on organisms and lead to total N/P decrease and greenhouse gas emissions increase on ecosystems while causing cell apoptosis, antioxidant system reaction, and inflammation in human health. Within the framework of ecological and human health risk assessment, we used the risk quotient (RQ) and physiologically based pharmacokinetic (PBK) models as examples to illustrate the importance of considering aging characteristics and the degree of MNPs in the process of data acquisition, model building, and formula evaluation. Given the ecological and health risks of aged MNPs, our urgent call for more studies of aged MNPs is to understand the potential hazards of MNPs in real-world environments.

The Secretary of Social Development (SEDESOL) and the National Council to Prevent Discrimination developed the National Survey on Discrimination in Mexico to assess the amount of discrimination in the everyday lives of Mexican citizens. Specifically, SEDESOL wanted to analyze the problem from the perspectives of the general population and from specific vulnerable populations. For this reason, the survey developed seven different questionnaires: a general questionnaire for the general population and six separate questionnaires for targeted vulnerable populations. These targeted vulnerable populations included: a) population of elderly people, b) indigenous population, c) population with non-Catholic religious beliefs, d) female population, e) people with disabilities, and f) individuals with non-heterosexual preferences, which became a case study due to the difficulty covering that specific targeted population.

This dataset examines the responses of 761 individuals among the elderly population in Mexico. These individuals were asked questions regarding the following: general views on discrimination; how they feel society generally treats them; whether or not they have experienced discrimination based on their age; what action should be taken to prevent elderly discrimination; the role of government in preventing discrimination towards the elderly population; the life opportunities of the elderly; their views on other vulnerable populations; and whether or not discrimination towards the elderly has changed over the years. The methodology, questionnaire, and responses in the dataset were translated from Spanish into English.

Longitudinal and Intergenerational Determinants of Aging and Mortality was funded by the National Institute on Aging to add critical information on cause of death to a new large-scale data resource, the Longitudinal, Intergenerational Family Electronic Micro-database (LIFE-M). Enhancing the LIFE-M with cause of death will facilitate innovative research on the relationship of longevity and cause of death with demographic, socio-economic, and early-life environmental factors for family networks across four generations.The grant had the following specific aims:(1) Use “Smart Indexing” technology to digitize and cross-validate hand-written cause-of-death information;(2) Link digitized causes of death to the LIFE-M database and create documentation for this new variable for public use; and(3) Publicly release the causes of death variable and documentation with the LIFE-M dataset, metadata, and supporting documentation.

Cardiovascular diseases were one leading causes of death among the aging population across India between 2017 and 2019. Cardiovascular diseases accounted to 29 percent of the total share. Diabetes mellitus accounted for over three percent of the share of leading causes of death among people older than 70 years old during the same time period.

Disability, Independence and Dependency Situations Survey: Reason for not receiving any type of social service by gender and age. Population aged 6 and over with a disability that has needed some type of social service and has not received it. National.

This table contains 6720 series, with data for years 1994 - 1998 (not all combinations necessarily have data for all years). This table contains data described by the following dimensions (not all combinations are available): Geography (5 items: Territories; Northwest Territories including Nunavut; Northwest Territories; Yukon ...), Age group (14 items: Total; 12 years and over; 12-19 years; 12-14 years; 15-19 years ...), Sex (3 items: Both sexes; Females; Males ...), Injuries (4 items: No injuries in past 12 months; Injuries in past 12 months; not stated; Injuries within past 12 months; Total population for the variable injuries ...), Characteristics (8 items: Number of persons; Low 95% confidence interval - number of persons; High 95% confidence interval - number of persons; Coefficient of variation for number of persons ...).

Prevalence of any chronic disease per 100 elderly population in India, 2017–18.