This dataset contains the Version 2.1 CYGNSS Level 2 Science Data Record which provides the time-tagged and geolocated average wind speed (m/s) and mean square slope (MSS) with 25x25 kilometer resolution from the Delay Doppler Mapping Instrument aboard the CYGNSS satellite constellation. This version supersedes Version 2.0. The reported sample locations are determined by the specular points corresponding to the Delay Doppler Maps (DDMs). A subset of DDM data used in the direct processing of the average wind speed and MSS is co-located inside of the Level 2 data files. Only one netCDF data file is produced each day (each file containing data from up to 8 unique CYGNSS spacecraft) with a latency of approximately 6 days (or better) from the last recorded measurement time. The Version 2.1 release represents the second science-quality release. Here is a summary of improvements that reflect the quality of the Version 2.1 data release: 1) revised Geophysical Model Functions (GMFs) for both Fully Developed Seas (FDS) and Young Seas with Limited Fetch conditions, to be consistent with the calibration changes made to the v2.1 Level 1 science data products.; 2) Revised covariance matrix between DDMA and LES versions of the FDS wind speed retrieval, used by the minimum variance estimator, resulting from changes made to the v2.1 Level 1 science data products; 3) Revised debiasing algorithm coefficients used by the FDS L2 retrieval algorithm, resulting from changes made to the v2.1 Level 2 science data products; 4) revised quality control (Q/C) flags related to the required level of consistency between DDMA and LES versions of the FDS wind speed retrieval (the errors in the two retrievals are now less correlated so larger discrepancies are allowed; if either retrieval is not available, the sample receives a fatal Q/C flag); 5) new Q/C flag related to the block type of the GPS satellite which provided the transmitted signal. Samples using block II-F signals receive a fatal Q/C flag due to the higher level of uncertainty in their radiated power; 6) revised wind speed uncertainty values as a function of RCG and wind speed, plus a new dependence of the uncertainty on GPS block type to reflect the higher uncertainty in GPS radiated power for block II-F satellites.

This data set provides level 1 (L1) polarimetric radar backscattering coefficient (sigma-0), multilook complex, polarimetrically calibrated, and georeferenced data products from the Airborne Microwave Observatory of Subcanopy and Subsurface (AirMOSS) radar instrument collected over the La Selva Biological Station in Costa Rica. The AirMOSS radar is a P-band (UHF) fully polarimetric synthetic aperture radar (SAR) currently operating in the 420-440 MHz band designed to measure root-zone soil moisture (RZSM) and is flown on a NASA Gulfstream-III aircraft. Flight campaigns took place at least biannually from 2012 to 2015 at 10 study sites across North America. The acquired L1 P-band radar backscatter data will be used to retrieve the RZSM at the study sites. Subsequent analyses will investigate both seasonal and inter-annual variability in soil moisture and the relationships to carbon fluxes and their associated uncertainties on a continental scale.

Sigma 1 receptor (S1R) has shown a preferable protective effect on left ventricular function, but whether it protects right ventricular (RV) function is still elusive.This study aimed to determine the effects of S1R on RV dysfunction secondary to pulmonary arterial hypertension.Sixty wild-type male Sprague–Dawley rats were randomly divided into the control group, the fluvoxamine group, the pulmonary arterial hypertension group and the pulmonary arterial hypertension combined with fluvoxamine group. Monocrotaline (60 mg/kg) was administered to induce pulmonary arterial hypertension, and fluvoxamine was given for 21 consecutive days to activate S1R after one week of monocrotaline administration. Echocardiographic, serologic, and histologic parameters, qRT-PCR, and western blotting were conducted after 4 weeks of monocrotaline administration.The expression of S1R was decreased in the right ventricle in pulmonary arterial hypertension. TAPSE, and the FAC of the right ventricle were significantly decreased, and RV EDP and the plasma concentration of N-terminal pro-B-type natriuretic peptide was increased in the pulmonary arterial hypertension group, but fluvoxamine partly restored those abnormalities (all P < 0.05). Moreover, pulmonary arteriole remodeling, and fibrosis and hypertrophy in the RV were shown in the pulmonary arterial hypertension group; interestingly, fluvoxamine recovered RV structural remodeling (all P < 0.05) but neither alleviated pulmonary arteriole remodeling nor reduced pulmonary artery pressure. Furthermore, S1R activation protects RV function by upgrading the NRF 2/HO 1-mediated antioxidant stress pathway. In conclusion, chronic S1R activation ameliorates structural remodeling and RV dysfunction secondary to pulmonary arterial hypertension without altering pulmonary artery pressure.

This data set provides level 1 (L1) polarimetric radar backscattering coefficient (sigma-0), multilook complex, polarimetrically calibrated, and georeferenced data products from the Airborne Microwave Observatory of Subcanopy and Subsurface (AirMOSS) radar instrument collected over the MOISST site in Oklahoma. The AirMOSS radar is a P-band (UHF) fully polarimetric synthetic aperture radar (SAR) currently operating in the 420-440 MHz band designed to measure root-zone soil moisture (RZSM) and is flown on a NASA Gulfstream-III aircraft. Flight campaigns took place at least biannually from 2012 to 2015 at 10 study sites across North America. The acquired L1 P-band radar backscatter data will be used to retrieve the RZSM at the study sites. Subsequent analyses will investigate both seasonal and inter-annual variability in soil moisture and the relationships to carbon fluxes and their associated uncertainties on a continental scale.