China Fertility Rate of Childbearing Women: 1st Birth data was reported at 1.417 % in 2021. This records a decrease from the previous number of 1.705 % for 2020. China Fertility Rate of Childbearing Women: 1st Birth data is updated yearly, averaging 2.232 % from Dec 1999 (Median) to 2021, with 22 observations. The data reached an all-time high of 3.170 % in 1999 and a record low of 1.417 % in 2021. China Fertility Rate of Childbearing Women: 1st Birth data remains active status in CEIC and is reported by National Bureau of Statistics. The data is categorized under China Premium Database’s Socio-Demographic – Table CN.GA: Population: No of Birth, Death, Natural Growth, Birth Rate, Death Rate and Natural Growth Rate, Life Expectancy, Dependency Ratio.

In 2024, the average number of children born per 1,000 people in China ranged at ****. The birth rate has dropped considerably since 2016, and the number of births fell below the number of deaths in 2022 for the first time in decades, leading to a negative population growth rate. Recent development of the birth rate Similar to most East-Asian countries and territories, demographics in China today are characterized by a very low fertility rate. As low fertility in the long-term limits economic growth and leads to heavy strains on the pension and health systems, the Chinese government decided to support childbirth by gradually relaxing strict birth control measures, that had been in place for three decades. However, the effect of this policy change was considerably smaller than expected. The birth rate increased from **** births per 1,000 inhabitants in 2010 to ***** births in 2012 and remained on a higher level for a couple of years, but then dropped again to a new low in 2018. This illustrates that other factors constrain the number of births today. These factors are most probably similar to those experienced in other developed countries as well: women preferring career opportunities over maternity, high costs for bringing up children, and changed social norms, to name only the most important ones. Future demographic prospects Between 2020 and 2023, the birth rate in China dropped to formerly unknown lows, most probably influenced by the coronavirus pandemic. As all COVID-19 restrictions were lifted by the end of 2022, births figures showed a catch-up effect in 2024. However, the scope of the rebound might be limited. A population breakdown by five-year age groups indicates that the drop in the number of births is also related to a shrinking number of people with child-bearing age. The age groups between 15 and 29 years today are considerably smaller than those between 30 and 44, leaving less space for the birth rate to increase. This effect is exacerbated by a considerable gender gap within younger age groups in China, with the number of females being much lower than that of males.

China Fertility Rate of Childbearing Women: 2nd Birth data was reported at 1.348 % in 2021. This records a decrease from the previous number of 1.606 % for 2020. China Fertility Rate of Childbearing Women: 2nd Birth data is updated yearly, averaging 1.108 % from Dec 1999 (Median) to 2021, with 22 observations. The data reached an all-time high of 2.436 % in 2017 and a record low of 0.872 % in 2011. China Fertility Rate of Childbearing Women: 2nd Birth data remains active status in CEIC and is reported by National Bureau of Statistics. The data is categorized under China Premium Database’s Socio-Demographic – Table CN.GA: Population: No of Birth, Death, Natural Growth, Birth Rate, Death Rate and Natural Growth Rate, Life Expectancy, Dependency Ratio.

As of 2023, the bulk of the Chinese population was aged between 25 and 59 years, amounting to around half of the population. A breakdown of the population by broad age groups reveals that around 61.3 percent of the total population was in working age between 16 and 59 years in 2023. Age cohorts below 25 years were considerably smaller, although there was a slight growth trend in recent years. Population development in China Population development in China over the past decades has been strongly influenced by political and economic factors. After a time of high fertility rates during the Maoist regime, China introduced birth-control measures in the 1970s, including the so-called one-child policy. The fertility rate dropped accordingly from around six children per woman in the 1960s to below two at the end of the 20th century. At the same time, life expectancy increased consistently. In the face of a rapidly aging society, the government gradually lifted the one-child policy after 2012, finally arriving at a three-child policy in 2021. However, like in most other developed countries nowadays, people in China are reluctant to have more than one or two children due to high costs of living and education, as well as changed social norms and private values. China’s top-heavy age pyramid The above-mentioned developments are clearly reflected in the Chinese age pyramid. The age cohorts between 30 and 39 years are the last two larger age cohorts. The cohorts between 15 and 24, which now enter childbearing age, are decisively smaller, which will have a negative effect on the number of births in the coming decade. When looking at a gender distribution of the population pyramid, a considerable gender gap among the younger age cohorts becomes visible, leaving even less room for growth in birth figures.

China Average Number of Childbearing Women data was reported at 338.553 Person th in 2021. This records a decrease from the previous number of 32,555.388 Person th for 2020. China Average Number of Childbearing Women data is updated yearly, averaging 327.211 Person th from Dec 1999 (Median) to 2021, with 22 observations. The data reached an all-time high of 35,725.466 Person th in 2010 and a record low of 265.610 Person th in 2019. China Average Number of Childbearing Women data remains active status in CEIC and is reported by National Bureau of Statistics. The data is categorized under China Premium Database’s Socio-Demographic – Table CN.GA: Population: No of Birth, Death, Natural Growth, Birth Rate, Death Rate and Natural Growth Rate, Life Expectancy, Dependency Ratio.

The total fertility rate in China increased by 0.02 children per woman (+1.72 percent) in 2022. In total, the fertility rate amounted to 1.18 children per woman in 2022. This increase was preceded by a declining fertility rate.The total fertility rate is the average number of children that a woman of childbearing age (generally considered 15 to 44 years) can hypothetically expect to have throughout her reproductive years. As fertility rates are estimates (similar to life expectancy), they refer to a hypothetical woman or cohort, and estimates assume that current age-specific fertility trends would remain constant throughout this person's reproductive years.Find more statistics on other topics about China with key insights such as death rate, number of tuberculosis infections , and crude birth rate.

China Fertility Rate of Childbearing Women data was reported at 3.127 % in 2021. This records a decrease from the previous number of 3.726 % for 2020. China Fertility Rate of Childbearing Women data is updated yearly, averaging 3.730 % from Dec 1999 (Median) to 2021, with 22 observations. The data reached an all-time high of 4.703 % in 2017 and a record low of 2.975 % in 2011. China Fertility Rate of Childbearing Women data remains active status in CEIC and is reported by National Bureau of Statistics. The data is categorized under China Premium Database’s Socio-Demographic – Table CN.GA: Population: No of Birth, Death, Natural Growth, Birth Rate, Death Rate and Natural Growth Rate, Life Expectancy, Dependency Ratio.

The fertility rate of a country is the average number of children that women from that country will have throughout their reproductive years. In 1930, China's fertility rate was 5.5 children per woman, and this number then dropped to just under five over the next fifteen years, as China experienced a civil war and the Second World War. The fertility rate rose rather quickly after this to over 6.1 in 1955, before dropping again in the late 1950s, as Chairman Mao's 'Great Leap Forward' failed to industrialize the nation, and resulted in widespread famine that killed an estimated 45 million people. In the decade following this, China's fertility rate reached it's highest level in 1970, before the implementation of the two-child policy in the 1970s, and the one-child policy** in the 1980s, which radically changed the population structure. The fertility rate fell to an all time low in the early 2000s, where it was just 1.6 children per woman. However this number has increased to 1.7 today, and the two-child policy was reintroduced in 2016, replacing the one-child policy that had been effective for over 36 years.

Although thyroid dysfunction in early pregnancy may have adverse effects on pregnancy outcomes, few studies have examined the relationship between maternal low free thyroxin (FT4) levels in both first and third trimesters of pregnancy and the incidence of adverse pregnancy outcomes. We hypothesized that low FT4 levels in either first or third trimesters of pregnancy may have different effects on pregnancy outcomes. The study included 6,031 mothers who provided both first and third pregnancy serum samples for analyses of thyroid function. Adverse pregnancy outcomes, such as gestational diabetes mellitus (GDM), pregnancy-induced hypertension and preeclampsia, were diagnosed using the oral glucose tolerance test, blood pressure and urine protein test. Serum metabolites like adenosine and its analogues were identified using hydrophilic interaction liquid chromatography (HILIC)-tandem mass spectrometry (MS/MS). The incidence of hypothyroidism in pregnant women tended to increase with age and pre-pregnancy body mass index (BMI). The incidence of GDM was negatively correlated with maternal FT4 levels during early pregnancy while the incidence of preeclampsia was negatively correlated with maternal FT4 levels during late pregnancy. The incidence of pregnancy-induced hypertension was not significantly correlated with maternal FT4 levels. The women who had isolated maternal hypothyroxemia (IMH) in the third trimester of pregnancy had an increased risk of developing preeclampsia. Some metabolites like adenosine and its analogues in the serum were significantly changed in pregnant mothers with IMH. In conclusion, low FT4 levels during pregnancy are a risk factor for GDM and preeclampsia. Adenosine and its analogues may be important bridges between IMH and preeclampsia.

Timing element of Split population model with all covariates (log odds).

Selection element of Split population model with all covariates (log odds).

Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide but the incidence and its risk factors in China is limited. The objective of this study is to investigate the incidence and the risk factors of PPH in Chinese women.Methods: A multi-center retrospective study of pregnant women at ≥28 weeks of gestation was conducted. Logistic regression was used to identify potential risk factors of PPH and receiver operating characteristic curve was used to evaluate the predictive performance of the identified risk factors. Subgroup analysis focusing on the number of fetus and the mode of delivery was conducted.Results: A total of 99,253 pregnant women were enrolled and 804 (0.81%) experienced PPH. The subgroup analysis revealed that the incidence of PPH was 0.75, 2.65, 1.40, and 0.31% in singletons, twin pregnancies, cesarean sections, and vaginal deliveries, respectively. Placenta previa and placenta accreta were the predominant risk factors of PPH in the overall population and all subgroups. A twin pregnancy was a risk factor for PPH regardless of the mode of delivery. Obesity, and multiparity were risk factors for PPH in both singletons and cesarean section cases, but the latter predicted a reduced probability of PPH in vaginal deliveries. Macrosomia was associated with increased risk of PPH in singletons or vaginal deliveries. In women who delivered vaginally, preeclampsia was associated with a higher risk of PPH. The areas under the curve for the overall cohort, singletons, twin pregnancies, cesarean section cases, and vaginal deliveries were 0.832 (95% confidence interval [CI] 0.813–0.851), 0.824 (95% CI 0.803–0.845), 0.686 (95% CI 0.617–0.755), 0.854 (95% CI 0.834–0.874), and 0.690 (95% CI 0.646–0.735), respectively.Conclusions: The risk factors of PPH varied slightly based on the number of fetuses and the mode of delivery, while placenta previa and placenta accreta were the two major risk factors. A combination of the identified risk factors yielded a satisfactory predictive performance in determining PPH in the overall cohort, singletons pregnancies, and women who delivered by cesarean section, whereas the performance was moderate in twin pregnancies and in women delivering vaginally.

Purpose: Expanded carrier screening (ECS) is an effective method to identify at-risk couples (ARCs) and avoid birth defects. This study aimed to reveal the carrier spectrum in the Chinese population and to delineate an expanded carrier gene panel suitable in China.Methods: Medical exome sequencing (MES), including 4,158 disease-causing genes, was offered to couples at two reproductive centers. It was initially used as a diagnostic yield for potential patients and then used for ECS. Clinical information and ECS results were retrospectively collected.Results: A total of 2,234 couples, representing 4,468 individuals, underwent MES. In total, 254 individuals showed genetic disease symptoms, and 56 of them were diagnosed with genetic diseases by MES. Overall, 94.5% of them were carriers of at least one disease-causing variant. The most prevalent genes were GJB2 for autosomal recessive disorders and G6PD for X-linked diseases. The ARC rate was 9.80%, and couples were inclined to undergo preimplantation genetic testing when diseases were classified as “profound” or “severe.”Conclusion: This study provided insight to establish a suitable ECS gene panel for the Chinese population. Disease severity significantly influenced reproductive decision-making. The results highlighted the importance of conducting ECS for couples before undergoing assisted reproductive technology.

BackgroundProlonged QT intervals have been observed in pregnant women, which predispose them to a higher risk of potentially lethal ventricular arrhythmias. This study was designed to evaluate the prevalence of QTc prolongation in Chinese hospitalized parturient women with single and twin pregnancies, and to explore potential risk factors associated with QTc prolongation.MethodsThis retrospective study included 1,218 patients from a large Chinese population between January 2014 and October 2020. Data from parturient women with single and twin pregnancies without pre-pregnancy cardiac diseases were collected. QTc was corrected by the Fridericia formula [QTc = QT/RR(1/3)], and QTc ≥ 460 ms for females was defined as prolonged QTc, QTc ≥ 500 ms was defined as severely prolonged QTc. The prevalence and common risk factors of QTc prolongation during pregnancy were analyzed in this cohort. Uni- and multivariable logistic regression analysis were performed to identify clinical parameters associated with QTc prolongation in this population.ResultsThe prevalence of QTc prolongation was 48.19% among this population, 10.56% in single pregnancy, 89.44% in twin pregnancies. The prevalence of severely prolonged QTc was 23.48% among the total cohort, 0.49% in single pregnancy, and 46.47% in twin pregnancies. The mean QTc interval was significantly longer in twin pregnancies than in single pregnancy (498.65 ± 38.24 vs. 424.96 ± 27.67 ms, P < 0.001). Systolic blood pressure, diastolic blood pressure, total cholesterol, serum uric acid, gestational hypertension and twin pregnancies were associated with QTc prolongation in parturient women.ConclusionThis is the first study to assess the prevalence and risk factors of QTc prolongation between single and twin pregnancies. QTc prolongation is more prevalent, and QTc intervals are significantly longer in twin pregnancies as compared to single pregnancy.

Supplementary files for article "Associations of childhood socioeconomic position and health with trajectories of grip strength from middle to older ages in populations from China and from England"BackgroundWe investigated associations of childhood socioeconomic position and health with trajectories of grip strength from middle to older ages in two distinct populations.MethodsWe used data from the China Health and Retirement Longitudinal Study (CHARLS, n = 16,701) and English Longitudinal Study of Ageing (ELSA, n = 12,695). Hand grip strength was measured at three timepoints in CHARLS (2011–2015) and four in ELSA (2001−2020). Random-effects growth models were applied to assess associations between each childhood factor and age trajectories of grip strength.FindingsLower parental education was associated with weaker grip strength, by 0·36 kg(95 % CI:0·17,0·56) for participants of illiterate (vs literate) parents in CHARLS and 1·88 kg(0·43,3·33) for participants of parents without education (vs ≥ high school) in ELSA, after adjusting for parental occupation and own adult socioeconomic position. Low parental occupation was associated with weaker grip strength, although the difference diminished after adjustment for adult socioeconomic position. Financial hardship was associated with weaker grip strength only in CHARLS, by 0·19 kg(0·01,0·38) after adjustment. Self-rated poor childhood health and school absenteeism were associated with weaker grip strength (both studies). Being confined to bed and hospitalised for more than a month due to health were associated with weaker grip strength only in CHARLS. Each additional childhood illness (only reported in ELSA) was associated with 0·52 kg(0·28,0·81) lower mean grip strength. Reported poor childhood health (CHARLS), low parental education and school absenteeism (ELSA) were associated with grip strength decline.InterpretationLower socioeconomic position and poor health in childhood were associated with weaker grip strength in later life in both Chinese and English populations. Addressing socioeconomic disparities and promoting health of children may enhance life-course physical capacity, promote healthy ageing and reduce age-related adversities.© The Author(s), CC BY-4.0

Bipolaris maydis is the pathogenic microorganism of southern corn leaf blight, a persistent biotic constraint responsible for substantial yield losses of corn worldwide. In the present study, 96 isolates from six representative fields growing single and multiple sweet corn cultivars in Pingnan, Fuqing, and Jian’ou in Fujian Province, which are characterized by different geographical characteristics and cropping patterns, were genetically analyzed using inter-simple sequence repeat (ISSR) markers to assess the impact of geographical origins and corn cultivars on B. maydis population differentiation. B. maydis isolates originated from diverse regions possessed higher genetic variety than those from single and multiple sweet corn cultivars. Phylogenetic analysis showed that the isolates from single and multiple sweet corn cultivars were randomly grouped into different clusters, with those from the same location tending to form clusters. A greater genetic differentiation among different geographical populations than between those from single and multiple sweet corn cultivars was observed by pairwise comparison. Hierarchical analysis indicated that among-population variation was higher when comparatively analyzed B. maydis populations from different locations than in those from single and multiple sweet corn cultivars. In conclusion, these results suggest that geographical origin acts a more considerable role in genetic differentiation of B. maydis than corn cultivar. Two divided genetic clusters were detected in the B. maydis populations from single and multiple sweet corn cultivars at the three locations in Fujian Province, with major genetic variation being derived within populations. The high haplotypic diversity and expected mating type ratio of 1:1 in combination with significant linkage disequilibrium suggested that a mixed reproductive strategy occurs in the B. maydis population in Fujian Province. This study will enrich the information on the role that geographical origins and corn cultivars play in the population structure of the pathogen as well as the reproductive strategies in B. maydis population in Fujian Province.

The clinical data of 837 singleton pregnant women were retrospectively analyzed and divided into normotensive control (n=238), gestational hypertension (n=213) and preeclampsia (n=386) groups. Fasting blood samples were collected by first-time examination after admission for measurements by standard techniques. Multivariate logistic regression was performed to assess independent factors correlated with pregnancy induced hypertension. Receiver operating characteristic (ROC) curves were constructed to examine diagnostic accuracy. Correlation analysis was used to evaluate the association between these parameters and Apgar score and birth weight.

BackgroundShenzhen has the largest and youngest foreign population among all cities in China. The reproductive health of pregnant women from different backgrounds is a social issue that deserves attention. In the past decade, China has liberalized its population policies to stimulate population growth, and the proportion of multiple births has continued to increase.MethodThis retrospective cohort included 526,654 newborns born in Baoan, Shenzhen, from January 1, 2009, to December 31, 2019, including 515,016 singletons and 11,638 twins or triplets. Univariate regression models were used to analyze the effects of maternal sociodemographic characteristics, physiological characteristics, medical history, antenatal care and other factors associated with single vs. multiple births and to elucidate the changing trends of different factors affecting multiple births in the past 11 years. Additionally, fetal development in multiple births was analyzed by generalized linear mixed models.ResultsThe rates of pregnancy complications, preterm birth, and advanced-age pregnancy were significantly higher in the multiple birth mothers than in single birth mothers, and more multiple pregnancies were achieved through assisted reproductive technologies. The rates of adverse outcomes such as stillbirth, malformation, hypoxia, and ultralow body weight in multiple fetuses were significantly higher than that in singleton fetuses. The trend analysis from 2009 to 2019 showed that the socioeconomic status and health level of mothers with multiple births improved over time, and the risk during pregnancy generally decreased. Simultaneously, the development indicators of multiple fetuses have improved year by year, and the proportion of adverse outcomes has also decreased significantly. A low pre-natal care utilization rate was shown to be detrimental to the development of multiple fetuses. Independent risk factors for hypoxia and very low birth weight were also identified. The differences in secular trends between two birth groups were further revealed by time series models.ConclusionThis study presented a comprehensive survey of multiple pregnancies in the area with the largest population inflow in China. This study identified the factors that affect the health of multiple birth mothers and their fetuses, particularly suggesting that preterm birth rates and the use of assisted reproduction remain high. The findings provide a basis for the formulation of individualized pre-natal care, assisted reproductive guidance and healthcare policies for multiple births.

A compendium of the Chinese government’s progressive fertility policy adjustments over the past decade.

育龄妇女生育率:三孩及以上在12-01-2021达0.363%，相较于12-01-2020的0.415%有所下降。育龄妇女生育率:三孩及以上数据按年更新，12-01-1999至12-01-2021期间平均值为0.184%，共22份观测结果。该数据的历史最高值出现于12-01-2019，达0.448%，而历史最低值则出现于12-01-2011，为0.129%。CEIC提供的育龄妇女生育率:三孩及以上数据处于定期更新的状态，数据来源于国家统计局，数据归类于中国经济数据库的社会人口 – Table CN.GA: Population: No of Birth, Death, Natural Growth, Birth Rate, Death Rate and Natural Growth Rate, Life Expectancy, Dependency Ratio。