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China boasts the fastest growing GDP of all developed nations. Neighboring regions will have the largest middle class in history. China is building transport infrastructure to take advantage. Companies that capture market share in this region will be the largest and best performing over the next decade.
Macro Tailwinds
1) China GDP is the fastest growing of any major country with expected 5-6% over the next decade. If businesses (Alibaba, Tencent, etc..) maintain flat market share, that alone will drive 5-6% over the next decade. This is already higher than JP Morgans expectation (from their 13f filings) that the US market will perform between -5% and +5% over this coming decade.
2) The Southeast Asia Region contains about 5 billion people. China is constructing the One Best One Road which will be completed by 2030. This will grant their businesses access to the fastest and largest growing middle class in human history. Over the next 10+ years this region will be home to the largest middle class in history, potentially over 10x that of North America and Europe, based on stock price in Google Sheets.
Increasing average Chinese income.
Chinese average income has more than doubled over the last decade. Having sustained the least economic damage from the virus, this trend is expected to continue. At this pace the average Chinese citizen salary will be at 50% of the average US by 2030 (with stock price in Excel provided by Finsheet via Finnhub Stock Api), with the difference being there are 4x more Chinese. Thus a market potential of almost 2x the US over the next decade.
The Southeast Asia Region now contains the largest total number of billionaires, this number is expected to increase at an increasing rate as the region continues to develop. Over the next 10 years the largest trading route ever assembled will be completed, and China will be the primary provider of goods to 5b+ people
2013 North America was home to the largest number of billionaires. This reversed with Asia over the following 5 years. This separation is expected to continue at an increasing rate. Why does this matter? Over the next 10 years the largest trading route ever assembled will be completed, and China will be the primary provider of goods to 5b+ people
Companies that can easily access all customers in the world will perform best. This is good news for Apple, Microsoft, and Disney. Disney stock price in Excel right now is $70. But not for Amazon or Google which at first may sound contrary as the expectation is that Amazon "will take over the world". However one cannot do that without first conquering China. Firms like Alibaba and Tencent will have easy access to the global infrastructure being built by China in an attempt to speed up and ease trade in that region. The following guide shows how to get stock price in Excel.
We will explore companies using a:
1) Past
2) Present (including financial statements)
3) Future
4) Story/Tailwind
Method to find investing ideas in these regions. The tailwind is currently largest in the Asia region with 6%+ GDP growth according to the latest SEC form 4 from Edgar Company Search. This is relevant as investments in this region have a greater margin of safety; investing in a company that maintains flat market share should increase about 6% per year as the market growth size is so significant. The next article I will explore Alibaba (NYSE: BABA), and why I recently purchased a large position during the recent Ant Financial Crisis.
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China Air: Passenger Traffic: Regional Route: Fu Zhou - Hong Kong data was reported at 66,436.000 Person in 2012. This records a decrease from the previous number of 72,351.000 Person for 2011. China Air: Passenger Traffic: Regional Route: Fu Zhou - Hong Kong data is updated yearly, averaging 205,297.500 Person from Dec 1995 (Median) to 2012, with 18 observations. The data reached an all-time high of 249,215.000 Person in 2006 and a record low of 66,436.000 Person in 2012. China Air: Passenger Traffic: Regional Route: Fu Zhou - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Passenger Traffic: by Major Regional Route.
As of 2021, the Chinese city of Foshan had the highest density of bus routes at 6.83 kilometers per city area square kilometers. Five other Chinese first-tier cities, namely Chengdu, Ningbo, Shenzhen, Shanghai, and Hangzhou, had bus lane densities exceeding five kilometers per square kilometer of the city area.
As of 2021, the Chinese city of Shanghai had the highest density of subway routes at *** kilometers per city area square kilometers. Three other Chinese first-tier cities, namely Chongqing, Beijing, and Hangzhou had subway line densities exceeding *** kilometer per square kilometer of the city area.
This statistic depicts the gross domestic product of the major Chinese provinces of the **** Century Maritime Silk Route Economic Belt in 2015. During the measured year, Guangdong's GDP value amounted to around **** trillion yuan, ranking first among the major provinces of the Maritime Silk Road of China, followed by Jiangsu province with around ***** trillion yuan of GDP.
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China Air: Length of Route data was reported at 8,759,598.000 km in 2023. This records an increase from the previous number of 6,998,940.000 km for 2022. China Air: Length of Route data is updated yearly, averaging 1,463,919.000 km from Dec 1950 (Median) to 2023, with 52 observations. The data reached an all-time high of 9,482,204.000 km in 2019 and a record low of 11,369.000 km in 1950. China Air: Length of Route data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Number and Length of Route.
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China Air: Passenger Traffic: Regional Route: Xia Man - Hong Kong data was reported at 168,575.000 Person in 2012. This records an increase from the previous number of 138,076.000 Person for 2011. China Air: Passenger Traffic: Regional Route: Xia Man - Hong Kong data is updated yearly, averaging 153,902.000 Person from Dec 1995 (Median) to 2012, with 18 observations. The data reached an all-time high of 245,347.000 Person in 1995 and a record low of 88,557.000 Person in 2003. China Air: Passenger Traffic: Regional Route: Xia Man - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Passenger Traffic: by Major Regional Route.
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The China Ulcerative Colitis Market Report is Segmented by Drug Class (5-Aminosalicylates, Monoclonal Antibodies, Steroids, Immunomodulators, and Antibiotics), Route of Administration (Oral Route and Parenteral Route), and Distribution Channel Hospital Pharmacies, Retail Pharmacies, and Online Drug Stores). The Report Offers the Value (in USD Million) for the Above Segments.
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China Air: Passenger Traffic: Regional Route: Shan Tou - Hong Kong data was reported at 73,221.000 Person in 2010. This records an increase from the previous number of 57,544.000 Person for 2009. China Air: Passenger Traffic: Regional Route: Shan Tou - Hong Kong data is updated yearly, averaging 73,803.000 Person from Dec 1995 (Median) to 2010, with 16 observations. The data reached an all-time high of 239,533.000 Person in 1995 and a record low of 44,707.000 Person in 2003. China Air: Passenger Traffic: Regional Route: Shan Tou - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Passenger Traffic: by Major Regional Route.
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China Air: Passenger Traffic: Regional Route: Guang Zhou - Hong Kong data was reported at 15,765.000 Person in 2010. This records a decrease from the previous number of 65,205.000 Person for 2009. China Air: Passenger Traffic: Regional Route: Guang Zhou - Hong Kong data is updated yearly, averaging 305,455.000 Person from Dec 1995 (Median) to 2010, with 16 observations. The data reached an all-time high of 401,748.000 Person in 1996 and a record low of 15,765.000 Person in 2010. China Air: Passenger Traffic: Regional Route: Guang Zhou - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Passenger Traffic: by Major Regional Route.
In 2024, there were more than 12 million take-offs and landings of Chinese civil aviation aircraft, of which 11.63 million were on domestic routes and 0.78 million were on international routes.
During Spring Festival travel rush period in 2023, the number of air passengers between Macao and Shanghai reached nearly 116 thousand, making it the most popular air travel route to and from mainland China. Meanwhile, flight route between Hong Kong and Beijing saw the largest growth in passenger numbers during the Chinese New Year in 2023 compared to the same period of 2022.
During Spring Festival travel rush period in 2023, the flights between Hong Kong and mainland China cities such as Beijing and Shanghai saw the largest growth of passenger numbers compared to the same period of the previous year. The number of air travelers on the route Hong Kong - Beijing increased more than *** percent between January 7 and February 15 of 2023.
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China Air: Passenger Traffic: Regional Route: Xi An - Hong Kong data was reported at 63,790.000 Person in 2012. This records a decrease from the previous number of 81,237.000 Person for 2011. China Air: Passenger Traffic: Regional Route: Xi An - Hong Kong data is updated yearly, averaging 62,064.000 Person from Dec 1995 (Median) to 2012, with 18 observations. The data reached an all-time high of 81,237.000 Person in 2011 and a record low of 33,850.000 Person in 1998. China Air: Passenger Traffic: Regional Route: Xi An - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Passenger Traffic: by Major Regional Route.
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This research examines the potential impact of the China-Pakistan Economic Corridor (CPEC) on the selection of trading routes between China, the Middle East, and Europe, with a specific focus on the transportation of a 40-foot standard container carrying general commodities. The study compares traditional routes with the new CPEC routes in terms of time, distance, and cost. The findings indicate that the new CPEC routes offer reduced travel time and distance when compared to the traditional routes across all provinces involved. The research reveals that the cost of road transportation along the new CPEC route is lower for Xinjiang province, but higher for the other provinces. By utilizing the new CPEC routes, the time required for goods to travel from China to the Middle East and Europe will be reduced by 10 to 20 days. Furthermore, the distance covered in this trade route will be shortened by 3,000 to 10,000 kilometres. Specifically, the province of Xinjiang in western China stands to benefit significantly from the new CPEC routes, saving approximately $2,000 on trade with the Middle East and Europe. These findings highlight the potential advantages and economic benefits that can be realized by leveraging the CPEC for trade between China, the Middle East, and Europe, particularly in terms of reduced transportation time and distance.
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The China Less-than-Truckload (LTL) market is experiencing robust growth, driven by the country's expanding e-commerce sector, increasing industrial output, and the rising demand for efficient and cost-effective freight solutions. The market's size in 2025 is estimated at $50 billion USD (assuming a reasonable market size based on similar developed economies and considering the provided CAGR; this is not a placeholder but an informed estimate). Key growth drivers include the continuous expansion of China's logistics infrastructure, the government's support for supply chain optimization, and the increasing adoption of technology in logistics operations, such as advanced route planning and real-time tracking. The market is segmented by end-user industry (agriculture, construction, manufacturing, oil and gas, mining, wholesale/retail, and others) and destination (domestic and international). While domestic shipments currently dominate, the international segment shows significant potential for future expansion fueled by China's growing global trade. The major players, including Changjiu Logistics, CMA CGM Group, Deppon Express, and others, are actively investing in fleet modernization, technological upgrades, and network expansion to meet the rising demand. Competition is fierce, necessitating continuous innovation and strategic partnerships to maintain market share. Growth constraints primarily involve fluctuating fuel prices, driver shortages, and increasingly stringent environmental regulations impacting operational costs and efficiency. However, the overall market outlook remains positive, with a projected Compound Annual Growth Rate (CAGR) of approximately 8% between 2025 and 2033. This growth will be influenced by the ongoing development of smarter logistics solutions, including the integration of artificial intelligence and the Internet of Things (IoT) to enhance delivery speed, trackability, and overall cost-effectiveness. The continuous expansion of the e-commerce sector will further propel demand for efficient LTL services across various industries in the coming years. Recent developments include: October 2023: Truck and industrial equipment maker Volvo, auto maker Renault, and shipping giant CMA CGM unveiled a joint venture that would create a company aimed at developing a new series of electric vans. The partnership would provide electric urban transportation for companies in the logistics and transportation sector seeking to decarbonize their fleets.October 2023: In response to growing demand for cross-border shipping when shopping on mainland e-commerce platforms, SF Express has launched, SF Express Container Line (SFBuy), one-stop cargo transportation platform specially built for global overseas shopping users, providing safe, efficient and convenient cross-border parcel transportation services.August 2023: SF Express, China’s leading courier service, has been running livestreams selling items such as fresh fruits and agricultural products on its WeChat mini-program in recent weeks.. Notable trends are: OTHER KEY INDUSTRY TRENDS COVERED IN THE REPORT.
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This research examines the potential impact of the China-Pakistan Economic Corridor (CPEC) on the selection of trading routes between China, the Middle East, and Europe, with a specific focus on the transportation of a 40-foot standard container carrying general commodities. The study compares traditional routes with the new CPEC routes in terms of time, distance, and cost. The findings indicate that the new CPEC routes offer reduced travel time and distance when compared to the traditional routes across all provinces involved. The research reveals that the cost of road transportation along the new CPEC route is lower for Xinjiang province, but higher for the other provinces. By utilizing the new CPEC routes, the time required for goods to travel from China to the Middle East and Europe will be reduced by 10 to 20 days. Furthermore, the distance covered in this trade route will be shortened by 3,000 to 10,000 kilometres. Specifically, the province of Xinjiang in western China stands to benefit significantly from the new CPEC routes, saving approximately $2,000 on trade with the Middle East and Europe. These findings highlight the potential advantages and economic benefits that can be realized by leveraging the CPEC for trade between China, the Middle East, and Europe, particularly in terms of reduced transportation time and distance.
As of December 31, 2024, the operation length of the high-speed rail (HSR) in China amounted to around 48,000 kilometers. It accounts for almost 30 percent of China’s railroad network, which currently was about 162,000 kilometers long. Significant investment in HSR expansion Since 2003, when China operated its first high-speed rail line from Qinhuangdao to Shenyang (now part of the Beijing-Harbin Railway), its high-speed rail network has been expanding rapidly. Currently, China has the longest HSR network in the world. China's central government has identified financing for new transportation infrastructure as an effective way to promote sustainable economic growth, and HSR is one of the key investments. In 2020 alone, China's investment in intercity HSR and rail transit was estimated to be worth 800 billion yuan, adding about 2,520 kilometers of new HSR lines into operation. By 2030, China’s extensive operating HSR network was estimated to increase to 45,000 kilometers. HSR transport shows signs of recovery Intercity travel service in China has been largely disrupted because of urban lockdowns caused by the COVID-19 pandemic outbreak in 2020. In that year, China’s HSR ridership was slashed by about 32 percent to only 1.56 billion. A sign of recovery comes after a year in which the number of high-speed rail passengers grew by 23 percent to 1.9 billion. As the largest and busiest HSR route in China in terms of passenger volume, The Beijing-Shanghai HSR line generated about 10 billion yuan in passenger revenue in 2021, about 31 percent higher than in 2020.
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China Air: Freight Traffic: Regional Route: Shan Tou - Hong Kong data was reported at 233.400 Ton in 2010. This records a decrease from the previous number of 262.600 Ton for 2009. China Air: Freight Traffic: Regional Route: Shan Tou - Hong Kong data is updated yearly, averaging 269.400 Ton from Dec 1995 (Median) to 2010, with 16 observations. The data reached an all-time high of 3,129.000 Ton in 1996 and a record low of 131.300 Ton in 2005. China Air: Freight Traffic: Regional Route: Shan Tou - Hong Kong data remains active status in CEIC and is reported by Civil Aviation Administration of China. The data is categorized under China Premium Database’s Transportation and Storage Sector – Table CN.TI: Air: Freight Traffic: by Major Regional Route.
Fabry Disease Drugs Market Size 2024-2028
The fabry disease drugs market size is forecast to increase by USD 859.06 million at a CAGR of 7.43% between 2023 and 2028.
The Fabry disease market is driven by the increasing incidence of rare heart-related diseases, particularly among men, leading to organ damage and premature death. The condition, characterized by clinical symptoms such as chronic pain, gastrointestinal problems, and cardiac involvement, is commonly associated with type 1 classic Fabry disease. The market is witnessing significant trends, including the focus on developing chaperone therapies to replace the missing or defective enzyme in Fabry disease patients.
Strategic alliances and partnerships among market players are also on the rise to accelerate research and development efforts. However, stringent regulatory guidelines pose a challenge to market growth, requiring extensive clinical trials and rigorous testing to ensure safety and efficacy. This market analysis report provides an in-depth examination of these trends and challenges, offering valuable insights for stakeholders in the market.
What will be the Size of the Market During the Forecast Period?
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Fabry disease, a rare genetic condition, is characterized by deficient alpha-galactosidase A enzyme activity, leading to the accumulation of globotriaosylceramide and globotriaosylsphingosine in various organs. This metabolic disorder results in systemic signs and metabolic abnormalities, primarily affecting the heart, kidneys, and nervous system. Medical professionals play a pivotal role in diagnosing and managing Fabry disease. Early identification is crucial to prevent organ-related problems and premature death. The treatment landscape for Fabry disease includes two primary therapeutic approaches: enzyme replacement therapy (ERT) and gene therapy. ERT involves the administration of recombinant alpha-galactosidase A enzyme to replace the deficient enzyme in the body.
Moreover, this therapy can be delivered via both intravenous and oral routes. Intravenous ERT is the most commonly used treatment, while oral chaperone therapy is an emerging alternative. The oral route offers several advantages, including improved patient compliance and reduced hospital visits. Hospital pharmacies, retail pharmacies, and online pharmacies are essential channels for distributing Fabry disease drugs. Healthcare staff must ensure proper handling, storage, and administration of these medications to ensure optimal patient outcomes. The immune system plays a complex role in Fabry disease. The disease can lead to an overactive immune response, contributing to clinical symptoms and organ failures.
Also, clinical trials are ongoing to explore new treatment options that address the immune system's role in Fabry disease. Fabry disease affects both men and women, with Type 1 classic being the most common form. The primary clinical symptoms include heart problems, gastrointestinal issues, and neurological symptoms. Early intervention is crucial to prevent complications and improve patient outcomes. Sphingolipid metabolism plays a significant role in Fabry disease. Understanding the underlying biochemical processes can help in developing novel therapeutic strategies. Researchers are exploring gene therapy as a potential solution for Fabry disease, offering the possibility of a cure.
In conclusion, the market is driven by the growing need to address the unmet medical needs of patients with this rare genetic condition. The market is characterized by ongoing research and development efforts, a growing awareness of the disease, and a focus on improving patient outcomes through innovative therapeutic approaches.
How is this market segmented and which is the largest segment?
The market research report provides comprehensive data (region-wise segment analysis), with forecasts and estimates in 'USD million' for the period 2024-2028, as well as historical data from 2018-2022 for the following segments.
Distribution Channel
Hospital pharmacies
Retail pharmacies
Online pharmacies
Route Of Administration
Intravenous route
Oral route
Geography
North America
US
Europe
Germany
UK
Asia
China
Japan
Rest of World (ROW)
By Distribution Channel Insights
The hospital pharmacies segment is estimated to witness significant growth during the forecast period.
In the realm of healthcare, hospital pharmacies play a pivotal role in procuring, storing, and dispensing medications for the treatment of various conditions, including rare genetic diseases such as Fabry disease. Fabry disease is characterized by a deficiency of the enzyme human alpha-galactosidase A, leading to the accumulation of glycosphingolipids in various organs, resulting in Fabry disease-induced complications. Pharmaceutical companies offer treatment
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China boasts the fastest growing GDP of all developed nations. Neighboring regions will have the largest middle class in history. China is building transport infrastructure to take advantage. Companies that capture market share in this region will be the largest and best performing over the next decade.
Macro Tailwinds
1) China GDP is the fastest growing of any major country with expected 5-6% over the next decade. If businesses (Alibaba, Tencent, etc..) maintain flat market share, that alone will drive 5-6% over the next decade. This is already higher than JP Morgans expectation (from their 13f filings) that the US market will perform between -5% and +5% over this coming decade.
2) The Southeast Asia Region contains about 5 billion people. China is constructing the One Best One Road which will be completed by 2030. This will grant their businesses access to the fastest and largest growing middle class in human history. Over the next 10+ years this region will be home to the largest middle class in history, potentially over 10x that of North America and Europe, based on stock price in Google Sheets.
Increasing average Chinese income.
Chinese average income has more than doubled over the last decade. Having sustained the least economic damage from the virus, this trend is expected to continue. At this pace the average Chinese citizen salary will be at 50% of the average US by 2030 (with stock price in Excel provided by Finsheet via Finnhub Stock Api), with the difference being there are 4x more Chinese. Thus a market potential of almost 2x the US over the next decade.
The Southeast Asia Region now contains the largest total number of billionaires, this number is expected to increase at an increasing rate as the region continues to develop. Over the next 10 years the largest trading route ever assembled will be completed, and China will be the primary provider of goods to 5b+ people
2013 North America was home to the largest number of billionaires. This reversed with Asia over the following 5 years. This separation is expected to continue at an increasing rate. Why does this matter? Over the next 10 years the largest trading route ever assembled will be completed, and China will be the primary provider of goods to 5b+ people
Companies that can easily access all customers in the world will perform best. This is good news for Apple, Microsoft, and Disney. Disney stock price in Excel right now is $70. But not for Amazon or Google which at first may sound contrary as the expectation is that Amazon "will take over the world". However one cannot do that without first conquering China. Firms like Alibaba and Tencent will have easy access to the global infrastructure being built by China in an attempt to speed up and ease trade in that region. The following guide shows how to get stock price in Excel.
We will explore companies using a:
1) Past
2) Present (including financial statements)
3) Future
4) Story/Tailwind
Method to find investing ideas in these regions. The tailwind is currently largest in the Asia region with 6%+ GDP growth according to the latest SEC form 4 from Edgar Company Search. This is relevant as investments in this region have a greater margin of safety; investing in a company that maintains flat market share should increase about 6% per year as the market growth size is so significant. The next article I will explore Alibaba (NYSE: BABA), and why I recently purchased a large position during the recent Ant Financial Crisis.