The Chloroform Price Index in North America rose by 0.4% QoQ in Q2 2025, with spot prices reaching USD 603/MT FOB Texas by the final week of June.

Get the latest insights on price movement and trend analysis of Chloroform in different regions across the world (Asia, Europe, North America, Latin America, and the Middle East Africa).

According to Cognitive Market Research, the global Chloroform market size will be USD 2842.5 million in 2024. It will expand at a compound annual growth rate (CAGR) of 6.00% from 2024 to 2031.

North America held the major market share for more than 40% of the global revenue with a market size of USD 1137.00 million in 2024 and will grow at a compound annual growth rate (CAGR) of 4.2% from 2024 to 2031.
Europe accounted for a market share of over 30% of the global revenue with a market size of USD 852.75 million.
Asia Pacific held a market share of around 23% of the global revenue with a market size of USD 653.78 million in 2024 and will grow at a compound annual growth rate (CAGR) of 8.00% from 2024 to 2031.
Latin America had a market share of more than 5% of the global revenue with a market size of USD 142.13 million in 2024 and will grow at a compound annual growth rate (CAGR) of 5.4% from 2024 to 2031.
Middle East and Africa had a market share of around 2% of the global revenue and was estimated at a market size of USD 56.85 million in 2024 and will grow at a compound annual growth rate (CAGR) of 5.7% from 2024 to 2031.
The Technical Grade held the highest Chloroform market revenue share in 2024.

Market Dynamics of Chloroform Market

Key Drivers for Chloroform Market

Increased Pharmaceutical Industry to Increase the Demand Globally

Chloroform remains a critical solvent in the pharmaceutical industry, playing a key function in the extraction of antibiotics, vitamins, and flavors. Its efficacy in dissolving diverse compounds makes it vital in the components of numerous medicinal drugs and dietary supplements. The developing worldwide population, coupled with an increasing call for healthcare merchandise, drastically drives this zone's reliance on chloroform. As healthcare desires extend, in particular in developing areas, the pharmaceutical industry's call for chloroform is projected to rise, ensuring its persevered importance in the extraction and production approaches of critical healthcare merchandise.

Chemical Industry to Propel Market Growth

Chloroform serves as an essential intermediate within the production of plastics, prescribed drugs, dyes, and pesticides. Its flexible residences make it fundamental in synthesizing a huge variety of chemical merchandise. The growth of the chemical industry, pushed by way of technological improvements and elevated demand for various chemical-based totally merchandise, without delay affects the call for chloroform. As the industry expands, especially in areas with speedy industrialization and urbanization, the want for efficient and reliable intermediates like chloroform keeps thrusting upward. Consequently, the sturdy improvement of the chemical sector ensures a sustained demand for chloroform, reinforcing its important function in various manufacturing methods.

Restraint Factor for the Chloroform Market

Health Risks to Limit the Sales

Chloroform is thought to be carcinogenic and can cause extreme liver and kidney harm with extended publicity. Due to these sizable health risks, its use has been heavily restrained by means of stringent regulations worldwide. Growing attention approximately chloroform's toxicity has caused its phased reduction in lots of commercial packages, specially in sectors where safer alternatives are available. Regulatory bodies have carried out strict tips to restrict exposure and mitigate ability health dangers related to chloroform. As a result, industries are increasingly adopting safer solvents and techniques, contributing to a great decline in chloroform utilization and reinforcing the commitment to ensuring public health and safety.

Impact of Covid-19 on the Chloroform Market

The COVID-19 pandemic appreciably impacted the chloroform market, inflicting disruptions in delivery chains and fluctuations in calls. Initial lockdowns and regulations brought about reduced business activity, which reduced chloroform intake in production approaches. However, as the pharmaceutical sector skilled heightened demand for clinical components and remedies, the need for chloroform in drug systems saw a few restorations. The pandemic also expanded the frenzy for safer and more sustainable options, affecting lengthy-term market dynamics. Additionally, regulatory scrutiny increased, with a more emphasis on safety and environmental impact. Overall, even as the pandemic created quick-time period cha...

The global Chloroform Market size is expected to reach USD 9.45 Billion in 2032 registering a CAGR of 2.6%. Our report provides a comprehensive overview of the industry, including key players, market share, growth opportunities and more.

The Kenyan chloroform market reduced to $15M in 2024, declining by -7.9% against the previous year. Over the period under review, consumption showed a perceptible curtailment. Over the period under review, the market attained the peak level at $27M in 2020; however, from 2021 to 2024, consumption remained at a lower figure.

North America Chloroform market size will be USD 1137.00 million in 2024 and will grow at a compound annual growth rate (CAGR) of 4.2% from 2024 to 2031. North America has emerged as a prominent participant, and its sales revenue is estimated to reach USD 1649.8 Million by 2031. This growth is mainly attributed to the region's Demand from the pharmaceutical and chemical industries.

The Ethiopian chloroform market shrank dramatically to $5.8K in 2024, declining by -49.4% against the previous year. This figure reflects the total revenues of producers and importers (excluding logistics costs, retail marketing costs, and retailers' margins, which will be included in the final consumer price). Over the period under review, consumption showed a abrupt slump.

Chloroform Market Outlook

As per our latest research, the global chloroform market size was valued at USD 7.2 billion in 2024, reflecting a solid foundation for this essential chemical compound across diverse industries. The market is projected to grow at a CAGR of 2.8% during the forecast period, reaching a forecasted size of USD 9.1 billion by 2033. This steady growth is primarily driven by the sustained demand for chloroform as a key intermediate in the pharmaceutical and chemical manufacturing sectors, coupled with advancements in laboratory applications and stringent quality standards across the globe.

One of the principal growth factors propelling the chloroform market is the rising demand from the pharmaceutical industry. Chloroform serves as a crucial solvent and reagent in the synthesis of various pharmaceutical compounds, including anesthetics and antibiotics. With the ongoing expansion of the global pharmaceutical sector, especially in emerging economies, the need for high-purity chloroform has intensified. Additionally, the increasing focus on drug discovery and development, as well as the growing prevalence of chronic diseases, has led to a surge in pharmaceutical production, thereby boosting the demand for chloroform. The market’s growth is further supported by the continuous investments in research and development activities, which are aimed at discovering novel pharmaceutical formulations and improving existing processes.

Another significant driver is the extensive use of chloroform in the chemical industry. Chloroform acts as a versatile intermediate in the production of refrigerants, agrochemicals, and dyes, among other chemical products. The chemical manufacturing sector has witnessed robust growth due to the rising demand for specialty chemicals and the expansion of end-use industries such as agriculture, automotive, and electronics. As environmental regulations become more stringent, manufacturers are increasingly focusing on adopting advanced production technologies that minimize emissions and improve efficiency. This has led to the development of eco-friendly chloroform production processes, further stimulating market growth. The integration of sustainable practices and the adoption of circular economy principles are also expected to create new opportunities for chloroform manufacturers in the coming years.

The laboratory and research sector has also contributed significantly to the growth of the chloroform market. Chloroform is widely used in laboratories for analytical and preparative purposes, including DNA extraction, chromatography, and sample preservation. The rising number of research institutes, coupled with increased funding for scientific research and technological innovations, has fueled the demand for analytical-grade chloroform. Additionally, the growing emphasis on quality control and regulatory compliance in laboratory practices has necessitated the use of high-purity reagents, further driving the market. The increasing adoption of automation and digitalization in laboratory workflows has also enhanced the efficiency and accuracy of chloroform-based processes, thereby supporting market expansion.

From a regional perspective, the Asia Pacific region continues to dominate the global chloroform market, accounting for a significant share of overall consumption and production. This is largely attributed to the presence of major pharmaceutical and chemical manufacturing hubs in countries such as China, India, and Japan. North America and Europe also represent substantial markets, driven by advanced healthcare infrastructure, stringent regulatory standards, and a strong focus on research and development. Meanwhile, Latin America and the Middle East & Africa are witnessing gradual growth, supported by increasing investments in industrial and healthcare sectors. The regional distribution of market share is expected to remain dynamic, with emerging economies playing a pivotal role in shaping future trends.

Grade Analysis

The chloroform market is segmented by grade into Analytical Reagent, General Purpose, and Others, each catering to distinct end-use requirements. Analytical Reagent grade chloroform is characterized by its high purity and stringent quality standards, making it indispensable for laboratory and research applications. This segment has witnessed robust growth due to the increasing demand for precise and reliable analytical results in pharmaceutical and chemical research. Laboratories and research institutes across the globe a

The Myanmar's chloroform market was finally on the rise to reach $882 in 2024, after five years of decline. In general, consumption, however, continues to indicate a noticeable contraction. Over the period under review, the market hit record highs at $46K in 2018; however, from 2019 to 2024, consumption remained at a lower figure.

Europe Chloroform market USD 852.75 million in 2024 and will grow at a compound annual growth rate (CAGR) of 4.5% from 2024 to 2031. Use in the production of hydrofluorocarbon refrigerants is expected to aid the sales to USD 1213.8 million by 2031

Asia Pacific Chloroform market USD 653.78 million in 2024 and will grow at a compound annual growth rate (CAGR) of 8.00% from 2024 to 2031. Growing pharmaceutical manufacturing and chemical synthesis activities is expected to aid the sales to USD 1094.2 million by 2031

Chloroform Market Outlook

The global chloroform market size was valued at approximately USD 7.5 billion in 2023 and is projected to reach around USD 10 billion by 2032, growing at a Compound Annual Growth Rate (CAGR) of 3.2% during the forecast period. The primary growth driver for the chloroform market is its extensive use across various industries, including pharmaceuticals, chemicals, and agrochemicals. The increasing demand for chloroform as a solvent and reagent, coupled with its critical role as an intermediate in chemical syntheses, underpins market expansion. Additionally, the increasing investment in research and development activities across the pharmaceutical industry is boosting the demand for high-purity chloroform grades.

The pharmaceutical industry is witnessing substantial growth due to the rising prevalence of chronic diseases and the subsequent demand for effective medications. Chloroform, being a vital solvent in pharmaceutical formulations and as a reagent in drug development, is experiencing a surge in demand. Moreover, the growing focus on the development of generic drugs and biologics necessitates the use of chloroform in various stages of drug manufacturing and quality control. This industryÂ’s robust expansion is poised to significantly contribute to the chloroform market growth over the forecast period.

The agrochemical industry is another major sector driving the demand for chloroform. As the global population continues to rise, there is an increasing need for efficient agricultural practices to meet food security demands. Chloroform is extensively used in the production of herbicides, fungicides, and pesticides. Its role as an intermediate in the synthesis of these agrochemicals is crucial, thereby fueling market growth. Additionally, the advancements in agrochemical formulations and the development of environmentally friendly pesticides are expected to further boost the demand for chloroform in this sector.

Environmental regulations and safety concerns related to the use of chloroform pose a significant challenge to market growth. Various regulatory bodies across the globe have implemented stringent guidelines on the production and usage of chloroform due to its potential environmental and health hazards. The compliance with these regulations necessitates substantial investments in advanced manufacturing technologies and safety protocols, thereby affecting the market dynamics. However, the ongoing research to develop safer alternatives and the adoption of green chemistry practices are expected to mitigate these challenges in the long run.

Chloroethane, also known as ethyl chloride, is another chemical compound that shares some similarities with chloroform in terms of its applications as a solvent and in chemical syntheses. It is particularly valued in the production of tetraethyllead, a gasoline additive, although its use has declined with the shift towards unleaded fuels. Despite this, chloroethane remains important in the pharmaceutical industry, where it is used as a local anesthetic and in the manufacture of certain drugs. The compound's versatility and effectiveness in these roles continue to support its demand, even as industries adapt to changing regulatory and environmental standards.

Grade Analysis

The chloroform market is segmented based on grade, including industrial grade, pharmaceutical grade, and analytical grade. Industrial grade chloroform holds a significant share of the market due to its widespread application in the chemical industry. This grade is primarily used as a solvent in various chemical processes, including the extraction and purification of products. Its relatively lower cost compared to other grades makes it a preferred choice for bulk applications. The industrial grade segment is expected to maintain its dominance throughout the forecast period, driven by the expansion of the chemical and agrochemical industries.

Pharmaceutical grade chloroform, known for its high purity, finds extensive application in the pharmaceutical industry. This grade is used in the formulation of drugs and as a reagent in various pharmaceutical processes. The stringent quality standards and regulatory requirements in the pharmaceutical industry necessitate the use of high-purity chloroform, thereby driving the demand for pharmaceutical grade. The increasing R&D activities and the

Latin America's Chloroform market will be USD 142.13 million in 2024 and is estimated to grow at a compound annual growth rate (CAGR) of 5.4% from 2024 to 2031. The market is foreseen to reach USD 226.5 million by 2031 due to the Expansion of chemical processing industries.

Industrial Chloroform Market Outlook

The global market size for industrial chloroform was estimated to be USD 4.5 billion in 2023, and it is projected to reach USD 6.8 billion by 2032, growing at a CAGR of 4.5% during the forecast period. The growth of the industrial chloroform market can be attributed to its extensive applications across various industries, including pharmaceuticals, agrochemicals, and chemical processing, among others.

One of the main driving factors for the industrial chloroform market is the rising demand from the pharmaceutical industry. Chloroform is widely used in the synthesis of antibiotics, vitamins, and other pharmaceutical products. The expansion of the global pharmaceutical market, fueled by an aging population and increased prevalence of chronic diseases, is a significant growth driver. Additionally, advancements in drug discovery and the need for high-quality chemical intermediates further bolster the demand for industrial chloroform.

Another crucial growth factor is the agrochemical sector. Chloroform serves as a solvent and intermediate in the production of various agrochemicals, including pesticides and herbicides. The increasing global population and the consequent demand for higher agricultural productivity are driving the agrochemical market. Farmers and agricultural businesses are continually seeking effective chemicals to boost crop yields, thus escalating the demand for chloroform as a vital component in agrochemical formulations.

Furthermore, the chemical processing industry represents a significant market for chloroform. It is employed as a solvent and reagent in various chemical reactions and processes. The ongoing industrialization and expansion of chemical manufacturing facilities, particularly in emerging economies, are pivotal in sustaining the market growth. The development of novel chemical processes and the need for efficient solvents are additional factors contributing to the rising demand for industrial chloroform.

From a regional perspective, Asia Pacific holds a dominant position in the industrial chloroform market. The rapid industrialization, urbanization, and the presence of a robust manufacturing sector in countries like China and India are key contributors to this dominance. North America and Europe also represent substantial market shares owing to their advanced pharmaceutical and chemical industries. Additionally, Latin America and the Middle East & Africa are expected to witness moderate growth, driven by the expansion of their respective agricultural and chemical sectors.

Application Analysis

The application of chloroform in the pharmaceutical sector is one of its most significant uses, accounting for a substantial share of the market. Chloroform is employed in the extraction and production of various drugs and pharmaceutical products. It acts as a solvent for antibiotics, vitamins, and other compounds, making it indispensable for pharmaceutical manufacturing. The rising demand for advanced medications and ongoing research and development activities in the pharmaceutical industry contribute to the sustained demand for chloroform in this application segment.

In the agrochemical industry, chloroform finds extensive use as a solvent and intermediate in the synthesis of pesticides, herbicides, and fungicides. The global push towards enhancing agricultural productivity to meet the food demands of an increasing population has led to a surge in the use of agrochemicals. Chloroform's efficacy in dissolving organic materials makes it a preferred solvent in agrochemical formulations. The continuous advancements in agricultural technologies and the growing adoption of agrochemicals in modern farming practices are key factors driving the demand in this segment.

The chemical processing industry also represents a significant application segment for chloroform. It is used as a solvent, reagent, and intermediate in various chemical reactions and industrial processes. The expansion of chemical manufacturing facilities globally, particularly in emerging economies, underpins the growth of this segment. Additionally, the development of innovative chemical processes that require efficient solvents further elevates the demand for chloroform in chemical processing.

Laboratory use is another crucial application of chloroform. It is utilized in analytical chemistry for the preparation of samples, extraction processes, and as a solvent for various laboratory reagents. Academic and research institutions, as well as industrial laboratori

The global Chloroform market stood at approximately 757 thousand tonnes in 2024 and is anticipated to grow at a healthy CAGR of 2.74% during the forecast period until 2035.

Deuterated Chloroform Market Outlook

The global deuterated chloroform market size was valued at approximately USD 130 million in 2023 and is anticipated to grow to about USD 250 million by 2032, registering a robust CAGR of 7.2% during the forecast period. The growth of the deuterated chloroform market is primarily driven by its increasing application in NMR spectroscopy, which is extensively used in the pharmaceutical and chemical research industries for molecular analysis and structure determination.

The rising demand for accurate and high-resolution analytical techniques in pharmaceutical and chemical research is a major growth factor for the deuterated chloroform market. NMR spectroscopy, which relies on deuterated solvents like chloroform to reduce signal interference, is gaining prominence due to its non-destructive nature and ability to provide detailed information about molecular structures. This has spurred investments in research and development, propelling the demand for deuterated chloroform in laboratories and research institutions worldwide.

Furthermore, the expanding pharmaceutical industry, driven by a surge in drug discovery and development activities, has significantly contributed to the growth of the deuterated chloroform market. Pharmaceutical companies are increasingly adopting advanced analytical techniques to ensure the purity and efficacy of their products, leading to a heightened demand for deuterated solvents. As regulatory standards become more stringent, the need for precise analytical methods is anticipated to further boost market growth.

Technological advancements in NMR spectroscopy equipment are also playing a crucial role in market expansion. Modern NMR instruments are becoming more sophisticated, capable of providing more accurate and detailed spectra. This has increased the reliance on high-purity deuterated chloroform, as it is essential for maintaining the quality and reliability of NMR analyses. The continuous improvements in NMR technology are expected to sustain the demand for deuterated chloroform in the coming years.

Deuterium Labeled Compounds are gaining significant attention in the field of analytical chemistry and pharmaceutical research. These compounds, which include deuterated chloroform, are essential for enhancing the accuracy and sensitivity of various spectroscopic techniques. By replacing hydrogen atoms with deuterium, these compounds help in minimizing background noise and improving the resolution of NMR spectra. This makes them invaluable in the structural analysis and characterization of complex molecules, thereby supporting the development of new drugs and materials. The demand for deuterium labeled compounds is expected to rise as researchers continue to seek more precise and reliable analytical methods.

From a regional perspective, North America holds a significant share of the deuterated chloroform market, driven by the presence of major pharmaceutical and chemical research organizations. The United States, in particular, is a key market due to its advanced healthcare infrastructure and substantial investments in research and development. Europe also represents a substantial market, with countries like Germany, the UK, and France being prominent contributors. The Asia Pacific region is expected to witness the highest growth rate, owing to increasing R&D activities and expanding pharmaceutical manufacturing capabilities in countries like China, India, and Japan.

Purity Level Analysis

The purity level of deuterated chloroform is a critical determinant of its performance in various applications, particularly in NMR spectroscopy. The market is segmented into three major categories based on purity levels: 99.8%, 99.9%, and others. Deuterated chloroform with 99.8% purity is widely used in routine analytical applications where ultra-high purity is not as critical. This segment holds a significant share of the market due to its relatively lower cost and adequate performance in many standard NMR applications.

The 99.9% purity segment, however, is gaining traction due to the increasing demand for higher sensitivity and accuracy in NMR spectroscopy. This level of purity is essential for applications that require minimal interference and high precision, such as in the pharmaceutical industry for drug development and quality control. The growth of this segment is driven by the stringent regulatory requirements and the need for highly reliab

The Chloroform market is experiencing robust growth, driven by its diverse applications across various industries. While precise market size figures are unavailable, analyzing the provided timeframe (2019-2033), a reasonable estimate for the 2025 market size could be in the range of $1.5 billion to $2 billion, based on typical market sizes for specialty chemicals with similar applications. This signifies substantial potential for growth considering a CAGR (Compound Annual Growth Rate) needs to be provided . The market's expansion is fueled by increasing demand from the pharmaceutical industry for anesthetic and solvent purposes, the refrigeration sector for its use as a refrigerant, and the manufacturing of various chemicals and intermediates. Furthermore, advancements in technologies facilitating safer handling and transportation of Chloroform are contributing to market expansion. However, stringent environmental regulations concerning its volatile organic compound (VOC) nature and the growing preference for safer alternatives pose significant challenges to market growth. The competitive landscape is characterized by both large multinational corporations like BASF, Solvay, and Dow Chemical Company, and smaller regional players like Arihant Chemicals. This competition fosters innovation and drives price competitiveness in the market. The future outlook for the Chloroform market remains optimistic despite these challenges. Continuous research and development efforts focused on minimizing its environmental impact, coupled with ongoing technological advancements in safer handling, will likely alleviate some of the regulatory pressures. Further, exploring new applications and expansion into emerging markets could further accelerate market expansion. The strategic focus of key players on sustainability and safety will also play a vital role in shaping the market trajectory over the forecast period. This includes investing in safer production methods and exploring greener alternatives for some applications. Regional variations in market growth are expected, primarily driven by factors like regulatory landscapes, industrial development, and economic growth in specific regions.

The global chloroform market size was USD 7.10 Billion in 2021, Rising demand for chloroform for use in agricultural products, and wide range of applications as a solvent in various products

The Methyl Chloroform market, valued at $1263 million in 2025, is projected to experience steady growth, exhibiting a Compound Annual Growth Rate (CAGR) of 2.5% from 2025 to 2033. This moderate growth reflects a mature market with established players and relatively stable demand. Key drivers include its continued use as a solvent in various industrial applications, particularly in the cleaning and degreasing of electronic components and metal parts. However, increasing environmental regulations aimed at phasing out ozone-depleting substances and the emergence of greener alternatives are acting as significant restraints on market expansion. The market is segmented by application (e.g., cleaning, degreasing, other industrial uses) and geography, with regional variations in growth likely due to differing regulatory landscapes and industrial activity levels. Major players like INEOS Inovyn, Olin Corporation, and OxyChem dominate the market, leveraging their established production capabilities and distribution networks. The competitive landscape is characterized by both established multinational corporations and regional players, resulting in a dynamic interplay between pricing strategies and technological advancements. Future growth will hinge on the ability of manufacturers to adapt to stricter environmental regulations, innovate with more sustainable solutions, and cater to evolving industry needs. The forecast period (2025-2033) suggests a gradual increase in market size, driven by persistent demand in specific industrial niches despite environmental concerns. Growth in developing economies, where industrialization is accelerating, could provide some positive impetus, although this would need to offset the impact of regulatory pressures in developed markets. The competitive landscape will continue to evolve, with ongoing mergers and acquisitions, and investments in research and development possibly leading to improved efficiency and the introduction of more environmentally friendly alternatives. Companies will need to focus on sustainable practices and innovative product development to maintain competitiveness and secure a larger market share. Long-term prospects depend on the successful navigation of environmental regulations and the identification of new applications with lower environmental impact.

Global Chloroform Market was valued at 757.88 Thousand Tonnes in 2024 and is expected to reach 1020.36 Thousand Tonnes by 2035 with a CAGR of 2.77% during the forecast period.