NES: normalized enrichment score from GSEA; FDR Q-value calculated from permutation.

A set of three estimates of land-cover types and annual transformations of land use are provided on a global 0.5 x0.5 degree lat/lon grid at annual time steps. The longest of the three estimates spans 1770-2010. The dataset presented here takes into account land-cover change due to four major land-use/management activities: (1) cropland expansion and abandonment, (2) pastureland expansion and abandonment, (3) urbanization, and (4) secondary forest regrowth due to wood harvest. Due to uncertainties associated with estimating historical agricultural (crops and pastures) land use, the study uses three widely accepted global reconstruction of cropland and pastureland in combination with common wood harvest and urban land data set to provide three distinct estimates of historical land-cover change and underlying land-use conversions. Hence, these distinct historical reconstructions offer a wide range of plausible regional estimates of uncertainty and extent to which different ecosystem have undergone changes. The three estimates use a consistent methodology, and start with a common land-cover map during pre-industrial conditions (year 1765), taking different courses as determined by the land-use/management datasets (cropland, pastureland, urbanization and wood harvest) to attain forest area distributions close to satellite estimates of forests for contemporary period. The satellite based estimates of forest area are based on MODIS sensor. All data uses the WGS84 spatial coordinate system for mapping.

The second column gives the normalized enrichment score (NES) from GSEA analysis, the third column the FDR Q-value calculated by permutation, and the fourth column the functional category of the pathway.