As of January 1, 2025, Rome (Lazio) was the Italian province which registered the highest number of coronavirus (COVID-19) cases in the country. Milan (Lombardy) came second in this ranking, while Naples (Campania) and Turin (Piedmont) followed. These four areas are also the four most populated provinces in Italy. The region of Lombardy was the mostly hit by the spread of the virus, recording almost one sixth of all coronavirus cases in the country. The provinces of Milan and Brescia accounted for a large part of this figure. For a global overview, visit Statista's webpage exclusively dedicated to coronavirus, its development, and its impact.

As of January 1, 2025, the number of active coronavirus (COVID-19) infections in Italy was approximately 218,000. Among these, 42 infected individuals were being treated in intensive care units. Another 1,332 individuals infected with the coronavirus were hospitalized with symptoms, while approximately 217,000 thousand were in isolation at home. The total number of coronavirus cases in Italy reached over 26.9 million (including active cases, individuals who recovered, and individuals who died) as of the same date. The region mostly hit by the spread of the virus was Lombardy, which counted almost 4.4 million cases.For a global overview, visit Statista's webpage exclusively dedicated to coronavirus, its development, and its impact.

After entering Italy, the coronavirus (COVID-19) spread fast. The strict lockdown implemented by the government during the Spring 2020 helped to slow down the outbreak. However, in the following months the country had to face four new harsh waves of contagion. As of January 1, 2025, 198,638 deaths caused by COVID-19 were reported by the authorities, of which approximately 48.7 thousand in the region of Lombardy, 20.1 thousand in the region of Emilia-Romagna, and roughly 17.6 thousand in Veneto, the regions mostly hit. The total number of cases reported in the country reached over 26.9 million. The north of the country was mostly hit, and the region with the highest number of cases was Lombardy, which registered almost 4.4 million of them. The north-eastern region of Veneto counted about 2.9 million cases. Italy's death toll was one of the most tragic in the world. In the last months, however, the country saw the end to this terrible situation: as of November 2023, 85 percent of the total Italian population was fully vaccinated. For a global overview, visit Statista's webpage exclusively dedicated to coronavirus, its development, and its impact.

The first two cases of the new coronavirus (COVID-19) in Italy were recorded between the end of January and the beginning of February 2020. Since then, the number of cases in Italy increased steadily, reaching over 26.9 million as of January 8, 2025. The region mostly hit by the virus in the country was Lombardy, counting almost 4.4 million cases. On January 11, 2022, 220,532 new cases were registered, which represented the biggest daily increase in cases in Italy since the start of the pandemic. The virus originated in Wuhan, a Chinese city populated by millions and located in the province of Hubei. More statistics and facts about the virus in Italy are available here.For a global overview, visit Statista's webpage exclusively dedicated to coronavirus, its development, and its impact.

Since the spread of the coronavirus (COVID-19) in Italy, started in February 2020, many people who contracted the infection died. The number of deaths amounted to 198,683 as of January 8, 2025. On December 3, 2020, 993 patients died, the highest daily toll since the start of the pandemic. The region with the highest number of deaths was Lombardy, which is also the region that registered the highest number of coronavirus cases. Italy's death toll was one of the most tragic in the world. In the last months, however, the country saw the end to this terrible situation: as of November 2023, roughly 85 percent of the total Italian population was fully vaccinated. For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Facts and Figures page.

Italy went through five coronavirus waves during the pandemic. As of January 8, 2025, the number of active coronavirus cases in the country was equal to approximately 203,305. On January 23, 2022, there were 2,734,906 active infections in Italy, the highest figure since the start of the pandemic. Furthermore, the total number of cases (including active cases, recoveries, and deaths) in Italy reached 26.9 million, with the region mostly hit by the virus in the country being Lombardy. Despite this notably high number of infections, deaths and hospitalizations remain rather low, thanks to a very high vaccination rate. The virus originated in Wuhan, a Chinese city populated by millions and located in the province of Hubei. More statistics and facts about the virus in Italy are available here.For a global overview, visit Statista's webpage exclusively dedicated to coronavirus, its development, and its impact.

The trajectories of coarse-grained (CG) molecular dynamics (MD) simulations of
1) unmodified (FeigLab_NMR; FeigLab_PentamerNoPTM_POPC_Martini3b: 5 μs; 5 μs);
2) palmitoylated (FeigLab_PentamerCYSP43; PentamerCYSP44_POPC_Martini3b: 5 μs; 5 μs);
SARS-CoV-2 E protein pentamer in a POPC bilayer.

The trajectory of CG MD of system containing 2 pentamers in the membrane buckled in a single direction (BuckledMembrane_FeigLab_2xPentamerNoPTM_POPC_Martini3b: 1 μs).

FeigLab_Pentamer: https://github.com/feiglab/sars-cov-2-proteins/blob/master/Membrane/E_protein.pdb
FeigLab_NMR_Pentamer is assembled based on the transmembrane domain determined by NMR (PDB ID: 7K3G) and FeigLab model for the rest.

The trajectories of coarse-grained (CG) molecular dynamics (MD) simulations of
1) unmodified (NoPTM_POPC_Martini3b: 0.5 & 2.5 μs);
2) palmitoylated (CYSP40, CYSP43, CYSP 44, CYSP40/43, CYSP 40/44, CYSP 43/44, CYSP40/43/44_POPC_Martini3b: 0.5 μs);
3) glycosylated (ASNG66: 0.5 μs)
SARS-CoV-2 E protein in the monomeric form in a POPC bilayer.

The trajectories of CG MD (TMD;H2H3_NoPTM_POPC_Martini3b: 0.5 μs) of systems containing artificial proteins consisting of only transmembrane domain (TMD) or only cytoplasmic domain (H2H3) in a POPC bilayer.

The trajectory of CG MD (4xNoPTM_POPC_Martini3b: 0.5 mks) of the system containing 4 proteins with centers of mass fixed in the plane of the POPC bilayer (XY).

The trajectories of CG MD of systems containing 2 proteins in the membranes buckled in a single direction (CurvedMembrane1;2X_2xNoPTM_POPC_Martini3b: 1 μs) and in the membrane buckled in both directions (CurvedMembraneXY_2xNoPTM_POPC_Martini3b: 1 μs).

Simulations have been performed using the beta version of Martini 3 (CG) force field, running with the GROMACS 2020.1 under the conditions reported in bioRxiv 2021.03.10.434722.

Results of the logistic regression analysis for COVID-19 infections.

Air quality by means of NO, NOx, NO2, PM10, SO2 and O3 was measured at five sites in Graz, Austria (Süd (eng. South) - S, Nord (eng. North) - N, West (eng. West) - W, Don Bosco – D, Ost (eng. East) – O). In addition weather conditions like temperature, percipitation, relative humidity, pressure, wind speed and direction are added. The authors created binary temporal variables like weekday, month, season, year and day of year (numerical).

The data consist of 2343 rows and 66 columns with a timestamp from January 2014 to May 2020 in a daily frequency.

More details on measurement and the sites are available in Moser et al. [1] and [2]. The environmental data was provided by the Austrian government under the following license: CC-BY-4.0: Land Steiermark - data.steiermark.gv.at

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[1] Moser F, Kleb U, Katz H (2019) Statistische Analyse der Luftqualitätin Graz anhand von Feinstaub und Stickstoffdioxid. Graz

[2] https://www.umwelt.steiermark.at/cms/ziel/2060750/DE/

The number of inbound overnight stays in tourist establishments in Rome, Italy, dropped sharply in 2020 over the previous year due to the coronavirus (COVID-19) pandemic. Overall, overnight stays by inbound travelers in Rome totaled roughly four million in 2020, declining from over 26 million in 2019.

The coronavirus (COVID-19) pandemic hit global travel and tourism hard in 2020, with governments implementing lockdowns and emergency restrictions to limit the spread of the virus. In Italy, it was estimated that the pandemic caused a total loss of roughly 88 billion euros in tourist consumption that year. The hospitality sector experienced the highest decrease in consumption, losing 32 billion euros in 2020 over the previous year. Meanwhile, the estimated loss of food and drink services amounted to roughly 12 billion euros. Due to the health crisis, the share of GDP generated by travel and tourism in Italy nearly halved in 2020 when compared to 2019.

The coronavirus (COVID-19) pandemic had a significant impact on the short-term rental market in Italy between February and August 2020. On March 3, a week before the beginning of the country's lockdown, the cancellation level in Bergamo skyrocketed. On March 10, one day after the start of the lockdown, the ratio of cancellations versus bookings in Florence reached 784 percent, meaning that there were almost eight times more cancellations thank bookings. Similarly, this ratio in Rome and Venice reached 604 and 551 percent, respectively.

For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Facts and Figures page.

After decreasing notably due to the coronavirus pandemic in 2020, the number of residential real estate transactions in Rome, Italy, surged in 2021. A total of 39,000 home sales took place in 2021 - the highest number recorded during the whole observation period.

The vacancy rate in the office real estate sector in Rome amounted to nine percent in the fourth quarter of 2020. When comparing the market's performance in 2019 and 2020, it can be seen that the vacancy rate increased by nearly one percent. The increase in vacancy rates was one of the many effects that the coronavirus (COVID-19) pandemic had on the real estate market.

The coronavirus (COVID-19) pandemic is having a damaging impact on the hotel industry across Europe. The first case of coronavirus was confirmed on January 24 in France, shortly followed by other European countries. In February, the impact on revenues per available room (RevPar) in European capitals was still relatively small, with the exception of Prague and Rome. By March, lockdowns and restrictions on unnecessary travel were implemented in other countries in Europe, resulting in negative results across the capitals; Rome experienced an 86 percent drop in RevPar in March, while hotels in Prague recorded a 78 percent decline.

For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Facts and Figures page.

The direct contribution of travel and tourism to Rome's gross domestic product (GDP) declined sharply with the onset of the coronavirus (COVID-19) pandemic compared to 2019. While these industries' direct contribution to GDP in the Italian capital amounted to nearly 8.4 billion euros in 2022, it dropped to just above three billion euros in 2021. As forecast, this figure was expected to reach an estimated 5.9 billion euros in 2022, remaining below pre-pandemic levels.

Due to the outbreak of the coronavirus (COVID-19), many countries around the world were put into lockdown. This resulted in cities coming to a virtual standstill with bans imposed on travel, which in turn lead to reduced pollution from vehicles. During the period of March to April 2020, the French capital Paris saw nitrogen dioxide emissions reduce by an estimated 54 percent when compared to the same period in 2019. Milan, Rome and Madrid saw similar reductions

For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Fact and Figures page.

During lockdowns imposed due to the coronavirus (COVID-19), many cities around the world saw substantial reductions in the levels of PM2.5 pollution. Delhi, India is one of the most polluted cities in the world, but between March 23rd and April 13th 2020 it experienced a reduction of 60 percent when compared to the same period the previous year. The South Korean capital of Seoul experienced similarly large reductions.Rome, Italy was the only city that experienced an increase in particulate pollution during its lockdown when compared to 2019.

For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Fact and Figures page.

In March 2020, during the peak of the COVID-19 pandemic, Italy recorded the highest monthly number of deaths across the period January 2019-October 2024. The number of individuals who died in March 2020 was 86,500. Another critical month was November 2020, when 78,500 deaths were reported. By contrast, in September 2019, 46,500 deaths were recorded, the lowest number of fatalities within the past five years. The deaths registered from February to June 2024 were the lowest since 2019.