In mid-January, there will be about ***** COVID-19 vaccination sites in the United Kingdom. This vaccination program, described as the biggest in NHS history, aims at offering jabs to most care home residents by the end of January and the most vulnerable by mid-February. Vaccinations will be available at over a thousand general practitioner-led sites, *** hospitals, and ***** mega centers. These centers will be capable of delivering thousands of vaccinations each week.

Furthermore, the UK has plans to step up capacity even further in the coming weeks, bringing *** pharmacy-led pilot sites and a further ** mass vaccination centers into play. That would take the total number of coronavirus vaccination hubs to about *****. The first ***** mega centers will open in Birmingham, Bristol, London, Manchester, Newcastle-upon-Tyne, Stevenage, and Surrey.

For further information about the coronavirus (COVID-19) pandemic, please visit our dedicated Facts and Figures page.

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Context

Since the start of the COVID-19 pandemic there have been over 290 million confirmed infections and 5 million deaths reported worldwide. Because of the unprecedented burden on healthcare resources, many healthcare activities such as chronic disease management, cancer screening and cancer treatments have been cancelled or delayed. Consequently, referrals of suspected new cancers have reduced, with increases in cancer-related deaths predicted.

The full impact of the COVID-19 pandemic on patients with primary liver cancer (PLC) has yet to be determined, although European data reported a disruption to hepatocellular carcinoma (HCC) services, a reduction in incident cases and an impact on management during the first wave of the pandemic (February 2020 to May 2020).

The data was prospectively collected on all patients referred to the Newcastle-upon-Tyne NHS Foundation Trust (NUTH) hepatopancreatobiliary multidisciplinary team (HPB MDT) in the first 12 months of the pandemic (March 2020-February 2021), comparing to a retrospective observational cohort of consecutive patients presenting in the 12 months immediately preceding it (March 2019-February 2020). All new cases with a diagnosis of hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC) confirmed radiologically or histologically, following international guidelines, were included.

The objective is to assess the impact of the COVID-19 pandemic on patients with newly diagnosed liver cancer.

Attribute Information

1. Cancer: Cancer flag [Y/N]
2. Year: Categorical [Prepandemic (March 2019–February 2020)/Postpandemic(March 2020–February 2021)]
3. Month: Month of the year 1-12
4. Bleed: Spontaneous tumour haemorrhage [Y/N]
5. Mode Presentation: Surveillance, Incidental, or Symptomatic
6. Age: Age of the patitent
7. Gender: Male or Female [M/F]
8. Etiology: manner of causation of a disease or condition. Either "No established CLD" (chronic liver disease), "ARLD" (alcohol-related liver disease), "NAFLD" (non-alcoholic fatty liver disease), "HCV" (hepatitis C virus), "HH" (hereditary haemochromatosis), "PBC/AIH" (primary biliary cholangitis/autoimmune hepatitis), "HBV" (hepatitis B virus), or "Other".
9. Cirrhosis: Underlying liver disease [Y/N]
10. Size: Tumour diameter in mm
11. HCC TNM Stage: Hepatocellular carcinoma Tumour node metastasis Stage ("I", "II", "IIIA+IIIB", "IV")
12. HCC BCLC Stage: Hepatocellular carcinoma Barcelona Clinic for Liver Cancer Stage ("0", "A", "B", "C", "D")
13. ICC TNM Stage: Intrahepatic cholangiocarcinoma Tumour node metastasis Stage ("I", "II", "III", "IV")
14. Treatment grps: First-line treatment received ["OLTx" (orthotopic liver transplantation), "Resection", "Ablation", "TACE"" (transarterial chemoembolisation), "SIRT" (selective internal radiation therapy), "Medical", "Supportive care"]
15. Survival from MDM: Survival from Multidisciplinary meeting
16. Alive Dead: "Alive", "Dead"
17. Type of incidental finding: ("Primary care-routine", "Secondary care-routine", "Primary care-acute", "Secondary care-acute")
18. Surveillance programme: Patient in a formal surveillance programme ("Y", "N")
19. Surveillance effectiveness: Surveillance adherence over previous year ("Consistent", "Inconsistent", "Missed")
20. Mode of surveillance detection: Mode of incident surveillance test ["US" (ultrasound), "AFP alone" (alpha-fetoprotein alone), "CT/MRI"]
21. Time diagnosis 1st Tx:
22. Date incident surveillance scan: ("Y", "N")
23. PS: Performance status [0, 1, 2, 3, 4]
24. Time MDM 1st treatment: Time to Multidisciplinary meeting 1st treatment
25. Time decision to treat 1st treatment: Time decision to treat 1st treatment
26. Prev known cirrhosis: ["Y", "N"]
27. Months from last surveillance: Months from last surveillance

Citation

fedesoriano. (September 2022). COVID-19 effect on Liver Cancer Prediction Dataset. Retrieved [Date Retrieved] from https://www.kaggle.com/datasets/fedesoriano/covid19-effect-on-liver-cancer-prediction-dataset.

Acknowledgeme...

This is a large (1318 participants) survey of UK General Practitioners during the Covid-19 pandemic via online survey, April/May 2021. This measured Maslach Burnout Inventory Scores and FACIT-Sp-NI scores (a burnout score, and a spiritual health score) as well as gathering data on gender as GMC, ethnicity, religion, number of sessions per week worked, length of service, area of service, and area of training.

Monthly computer usage figures by branch library from April 2008 to present. Additional information Given as a percentage of the total available time computers can be booked. BIPC is the Business & IP Centre based within the City Library. Blakelaw temporarily relocated as of 12/07/2024. No PC's in temporary location, not collecting PC Usage from this date. Blank means no data available. In 2020, all libraries closed from 19 March included due to the Covid-19 outbreak. Newcastle Libraries began to re-open from 12th April 2021 and figures will not be reported for the period of the Covid-19 pandemic.

Monthly loan figures (number of items issued) by branch library for April 2008 to present. Additional information An issue is any item issued from the library catalogue Blank means no data available In 2020, all libraries closed from 19 March included due to the coronavirus outbreak. The re-opening of our libraries remained inline with government restrictions from July 2020 and responsive to local need, with many variations during the months of the Covid-19 pandemic. All Newcastle Libraries began to re-open from 12th April 2021.

This project is investigating the way residents of four rural villages adapted and adopted new and existing technologies during the pandemic to communicate within and across villages to share knowledge and resources, and for purposes of mutual aid. The project aims to explore the potential for new technologies that build on existing infrastructure to support intra-village communications and support. The first phase of the study involved data collection through interviews and an online survey with residents, community leaders, and admins of online groups and pages. The second phase of the study will seek to design prototypes to shape discussion around the potential for innovations in the villages to support their needs. The final stage of this will be the deployment of a new system of infrastructure.

This project adopts two main research instruments - two online questionnaires (2 surveys of circa 1400 UK ‘new’ homeworkers each, June-July 2020 & Dec-February 2021). The second instrument is a series of semi-structed interviews (4 x Interviews with 80 ‘new’ homeworkers across UK, May 2020 – July 2021).

The COVID-19 outbreak has forced companies to embrace home-based working (HBW) at such speed that they have had little opportunity to consider the impact on their workers. It can be argued that the crisis has led to the most significant, intensive social experiment of digital, HBW that has ever occurred. The current situation, which involves the whole household being based at home, is an unprecedented challenge which may be at least an intermittent fixture, for the next eighteen months (BBC Futures, 25/03/20).

The press have suggested that this revolution might also offer an opportunity for many companies to finally build a culture that allows long-overdue work flexibility ... many employees for companies who have sent all staff home are already starting to question why they had to go into the office in the first place (The Guardian, 13/02/20). These optimistic takes on the current patterns of work focus on HBW's emancipatory potential, offering flexibility, the lubrication of work and family responsibilities and the promise of increased productivity. Yet, this new world order, where the home becomes a multi-occupational, multi-person workplace and school, not only challenges boundaries but also conceptions of the domestic space.

The impact of homeworking is likely to present significant variation depending on organisational support, the worker's role, socio-economic status, employment status, as well as household composition and size of living space. There are significant concerns regarding intensified HBW, including poor work-life balance, enhanced domestic tensions and disproportionately negative impacts on those in lower socio-economic groupings. Moreover, HBW increases the proportion of time women (most often) spend on housework and childcare, reproducing and reinforcing gender roles within the new 'work-space'

We will examine in-depth this radical shift in working arrangements and how it impacts on the wellbeing and productivity of workers and their households. Using a combination of in-depth interviews with sixty participants, representing the spectrum of this novel group of homeworkers, as well as a large-scale survey, this project (Working@Home) will provide unrivalled insights into the experience of home-working for the UK population and will serve as a permanent record of the lives of citizens in this unprecedented time.

The research will be key in understanding the expectations that organisations have placed on workers, as well as the robustness of support systems that have been put in place, taking into account the rapid advancement of home working systems with almost no preparation and only limited existing support structures or expertise. The findings will provide a benchmark for the resilience of both individuals and businesses and demonstrate the potential for the robustness of the infrastructure in the return to a 'new normal' after the crisis.

In order to ensure that the findings from the project are accessible to all, we are developing a website (workingathome.org.uk) that will host up to date information on the progress of the project, details of the project team, guidance for participants as well as information regarding our webinar series. The project aims to produce guidance to individuals, organisations and policy makers on how to best manage the ongoing medical emergency from a home-working perspective as well as providing guidance for any future pandemic scenario.