Deaths registered in 2019 in England and Wales due to dementia and Alzheimer's disease, by sex, age group, ethnicity, region and place of occurrence. Includes analysis of comorbidities.

Data on causes of death (COD) provide information on mortality patterns and form a major element of public health information.

The COD data refer to the underlying cause which - according to the World Health Organisation (WHO) - is "the disease or injury which initiated the train of morbid events leading directly to death, or the circumstances of the accident or violence which produced the fatal injury".

The data are derived from the medical certificate of death, which is obligatory in the Member States. The information recorded in the death certificate is according to the rules specified by the WHO.

Data published in Eurostat's dissemination database are broken down by sex, 5-year age groups, cause of death and by residency and country of occurrence. For stillbirths and neonatal deaths additional breakdowns might include age of mother and parity.

Data are available for Member States, Iceland, Norway, Liechtenstein, Switzerland, United Kingdom, Serbia, Turkey, North Macedonia and Albania. Regional data (NUTS level 2) are available for all of the countries having NUTS2 regions except Albania.

Annual national data are available in Eurostat's dissemination database in absolute number, crude death rates and standardised death rates. At regional level the same is provided in form of 3-years averages (the average of year, year -1 and year -2). Annual crude and standardised death rates are also available at NUTS2 level. Monthly national data are available for 21 EU Member States from reference year 2019 and in 24 Member States from reference year 2022 in absolute numbers and standardised death rates.

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Dementia patients show worsening cognitive function over time, beyond what might be expected from typical aging.

Dementia affects memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgment. This is commonly accompanied by changes in mood, emotional control, behavior, or motivation.

Deaths - Alzheimer's disease and other dementias - Sex: Both - Age: Age-standardized (Rate) Source Institute for Health Metrics and Evaluation, Global Burden of Disease (2019) – processed by Our World in Data Date range 1990–2019 Unit deaths per 100,000 people Links http://ghdx.healthdata.org/gbd-results-tool The data of this indicator is based on the following sources: Institute for Health Metrics and Evaluation, Global Burden of Disease (2019) Data published by Global Burden of Disease Collaborative Network. Global Burden of Disease Study 2019 (GBD 2019) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2021.

Retrieved on September 22, 2021 Retrieved from http://ghdx.healthdata.org/gbd-results-tool How we process data at Our World in Data: All data and visualizations on Our World in Data rely on data sourced from one or several original data providers. Preparing this original data involves several processing steps. Depending on the data, this can include standardizing country names and world region definitions, converting units, calculating derived indicators such as per capita measures, as well as adding or adapting metadata such as the name or the description given to an indicator.

At the link below you can find a detailed description of the structure of our data pipeline, including links to all the code used to prepare data across Our World in Data.

Read about our data pipeline How to cite this data: In-line citation If you have limited space (e.g. in data visualizations), you can use this abbreviated in-line citation:

Institute for Health Metrics and Evaluation, Global Burden of Disease (2019) – processed by Our World in Data

Full citation

Institute for Health Metrics and Evaluation, Global Burden of Disease (2019) – processed by Our World in Data. “Deaths - Alzheimer's disease and other dementias - Sex: Both - Age: Age-standardized (Rate)” [dataset]. Institute for Health Metrics and Evaluation, Global Burden of Disease (2019) [original data].

Correction 21 September 2023 - We regret that an error in the number of deaths in NHS Fife in 2022 was discovered in Table 4a. An updated version of this table has now been published. This section presents information on the numbers of deaths which had an underlying cause of dementia or Alzheimer’s disease.

In 2022, there were ******* deaths due to dementia among those aged 65 years and older in the United States. Non-Hispanic white seniors accounted for ******* of these deaths. This statistic shows the number of deaths from dementia in the U.S. among those aged 65 years and older from 2018 to 2022, by race/ethnicity.

In 2022, the mortality rate due to Alzheimer's disease was 36 deaths per 100,000 people. This statistic displays the annual Alzheimer's disease mortality rate in the United States from 2000 to 2022. Scientists believe that early detection of Alzheimer's can be the best way to prevent or slow the course of the disease. Alzheimer’s disease Alzheimer’s disease, a progressive and incurable brain disease, is among the top ten leading causes of death in the U.S. as well as worldwide. Furthermore, over the past two decades, the number of deaths due to Alzheimer’s and other dementias in the United States increased by over 140 percent. As with other dementias, Alzheimer’s commonly affects older individuals, although it can be diagnosed earlier on in life. In the United States, the majority of people with Alzheimer’s disease are over 75 years of age. Initial symptoms include difficulties in memory and mood changes, but the disease gradually progresses to impair communication and judgment, behavioral changes, and deficits in movement and motor skills, such as difficulties with swallowing, which often becomes a contributing cause of death. Care and treatment The cost of care for individuals with Alzheimer’s is expected to increase over the next couple of decades, with costs to Medicare and Medicaid expected to reach 637 billion U.S. dollars by 2050. Due to the increasing burden of Alzheimer’s and other dementias on healthcare and social systems, research into treatment and prevention is a major focus. Several major pharmaceutical companies currently have multiple drugs for Alzheimer’s treatment in various stages of development; other research is focused on identifying early brain changes associated with the disease in order to provide early diagnosis and intervention. Furthermore, personal health strategies include reducing modifiable risk factors commonly associated with cardiovascular health, such as quitting smoking, maintaining a healthy diet, and staying socially, mentally, and physically active.

As of 2022, the United Kingdom had a mortality rate due to dementia of over ** per 100,000 population, followed by the Netherlands that recorded **** deaths per 100,000 population in 2022. This statistic displays the number of deaths due to dementia in selected European countries in 2022 (per 100,000 population).

Gender, age, place of death and cause(s) of death for the patients dying from Alzheimer’s disease compared to other dementia diagnoses and unspecified dementia.

Age-standardised mortality rates, hazard ratios, and leading cause analysis exploring risk of all-cause mortality, death involving and not involving coronavirus (COVID-19) by dementia diagnosis.

This statistic shows the percentage changes in selected causes of death due to diseases in the United States, between 2000 and 2022. The number of deaths caused by prostate cancer increased by 7.4 percent during this period. Changes in selected causes of deathThere has been a decrease in the rate of death caused by many diseases, including stroke and heart disease. However, the mortality rate due to Alzheimer’s disease increased by 142 percent from 2000 to 2022. Alzheimer’s disease caused 27.7 deaths per 100,000 population in 2023, making it the sixth leading cause of death in the United States. Mortality rates due to different diseases vary by different factors, including race and ethnicity. For example, cancer is the leading cause of death among Asians and Pacific Islanders in the United States, accounting for 22 percent of total deaths among this population, while heart disease is the leading cause of death among the white population. Ischemic heart disease is the leading cause of death worldwide, accounting for around nine million deaths in 2021. In the early 1900's, the mortality rate was primarily concentrated among people of younger ages, but increasingly, this has shifted to older population groups. In recent years, decreased mortality rates are often linked to improved medical care, such as new developments in medical technologies. Shifts in lifestyle habits such as decreased smoking rates and healthier diets may also attribute to lower mortality rates.

IntroductionInconsistencies of reports contributes to the underreporting of Alzheimer’s disease (AD) on death certificates. Whether underreporting exists within South Carolina has not been studied.MethodsWe conducted a prospective, population-based study on a cohort of persons (N = 78,534) previously diagnosed with AD and died between 2014–2019. We linked vital records with the South Carolina Alzheimer’s Disease and Related Dementias Registry to investigate their cause of death and survival rates. Descriptive analyses calculated frequencies of demographic and health-related characteristics. Turnbull’s method estimated the survival probabilities for different subgroups of patients. Hazard ratios were computed from the Cox proportional hazards model, adjusting for the following confounding variables of age at diagnosis, education level, gender, and race.ResultsThe top immediate cause of death was Alzheimer’s disease among all racial groups, except for Native American/American Indian. More females (60.3%) were affected by AD compared to males (39.7%). There is a 25% probability of survival, beyond 5 years, after AD diagnosis. Black/African American AD patients have the smallest risk of all-cause mortality across all racial/ethnic groups (HR 0.87; 95% CI, 0.85–0.89). Individuals with lower education had a lower likelihood of mortality.ConclusionAlthough AD was not underreported in the state of South Carolina further research is needed to develop protocols around classification of deaths among those diagnosed with dementia and comorbidities, including cardiovascular disease, to ensure dementia is properly reported as we move to prevent and treat Alzheimer’s disease by 2025 and beyond.

Global Dementia Mortality Share by Country (Units (Deaths)), 2023 Discover more data with ReportLinker!

Background: Dementia risk is reported as being higher in the north compared to the south, which may be related to vitamin D deficiency. If this were the case, an opposite gradient of risk would be observed in the southern hemisphere, but this has not been investigated previously. Methods: We calculated standardised mortality ratios (SMRs) for deaths in 2012 where dementia (Alzheimer's disease, vascular or unspecified dementia) was recorded as the underlying cause for 20 regions in Italy, 20 District Health Board areas in New Zealand and 29 Health Service areas in Chile. Results: Dementia SMRs were higher in northern than central or southern Italy. The inverse pattern was seen in women in New Zealand, with rates higher on South Island than North Island. However, dementia risk was raised in eight regions in the north and centre of Chile in both men and women. Conclusions: Geographical variation plays a key role in dementia risk, but patterns vary in men and women. In the northern hemisphere, dementia mortality is higher in the north, but the pattern in the southern hemisphere is more complex.

BackgroundObservational research suggests that individuals with dementia who have sepsis face a higher likelihood of death. However, whether there is a causal relationship between the two remains unknown.MethodsWe analyzed data from patients diagnosed with sepsis and dementia, extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. To examine the correlation between dementia and 28-day mortality in sepsis, we utilized Cox proportional hazards models. Following this, we performed a Mendelian randomization (MR) study with two samples to investigate the potential link between dementia and mortality within 28 days in sepsis.ResultsThis study included a total of 22,189 patients diagnosed with sepsis, among whom 1,346 cases (6.1%) had dementia. After adjusting for multiple confounding factors, dementia was associated with an increased risk of 28-day mortality in sepsis (HR = 1.25, 95% CI = 1.12–1.39, p < 0.001). In the MR analysis, there appeared to be a causal relationship between genetically predicted dementia with Lewy bodies (DLB) (OR = 1.093, 95% CI = 1.016–1.177, p = 0.017) and 28-day mortality in sepsis. However, there was no evidence of causality between any dementia (OR = 1.063, 95% CI = 0.91–1.243, p = 0.437), Alzheimer’s disease (AD) (OR = 1.126, 95% CI = 0.976–1.299, p = 0.103), vascular dementia (VD) (OR = 1.008, 95% CI = 0.93–1.091, p = 0.844), and the risk of 28-day mortality in sepsis.ConclusionIn the observational analysis, dementia was associated with an increased risk of 28-day mortality in septic patients. However, in the MR analysis, only DLB was associated with increased 28-day mortality in septic patients, with no observed correlation for other dementia subtypes.

This statistic shows the rate of death for dementia in the U.S. in 2017, by age. In 2017, there were around 66.7 deaths in which dementia was the underlying cause per 100,000 population. However, the death rate for dementia among those aged 85 years and over was 2,707.3 per 100,000 population.

Odds ratios (OR) and 95% confidence intervals (CI) are reported.

Global Dementia Mortality by Country, 2023 Discover more data with ReportLinker!

CONTEXT AND OBJECTIVE: Alzheimer's disease is a common cause of dementia and identifying possible spatial patterns of mortality due to this disease may enable preventive actions. The objective of this study was to identify spatial distribution patterns of mortality due to Alzheimer's disease in the state of São Paulo.DESIGN AND SETTING: Ecological and exploratory study conducted in all municipalities in the state of São Paulo.METHODS: Data on Alzheimer's disease mortality in the state of São Paulo between 2004 and 2009 were obtained from DATASUS (the Department of Informatics in the Brazilian Ministry of Health). Death rates per 100,000 inhabitants were then calculated and spatial analysis was performed by constructing a death rate map, global Moran index and local Moran index, which were used to obtain the Moran map. The kernel technique was also applied. The Terra View 4.0.0 software was used.RESULTS: 13,030 deaths due to Alzheimer were reported in the state of São Paulo (rate of 5.33 deaths/100,000 inhabitants). São José do Rio Preto, Ribeirão Preto, Bauru and Araçatuba had higher rates. The Moran index was I = 0.085 (P < 0.002). The Moran map identified 42 municipalities that merit intervention and the kernel estimator identified a high density of deaths in the northwestern region of the state.CONCLUSION: Higher densities of deaths due to Alzheimer were concentrated more to the north and northwest of the state of São Paulo. It was possible to identify municipalities that have priority for interventions to reduce the death rates due to this disease.

Objective: To evaluate the risk of death in relation to incident antiepileptic drug use compared with non-use in people with Alzheimer’s disease (AD) through the assessment in terms of duration of use, specific drugs and main causes of death. Methods: The MEDALZ cohort includes all Finnish persons who received a clinically verified AD diagnosis (N=70718) in 2005‒2011. Incident AED users were identified with 1-year washout period. For each incident AED user (n=5638) one non-user was matched according to sex, age and time since AD diagnosis. Analyses were conducted with Cox proportional hazards models and inverse probability of treatment weighting (IPTW). Results: Nearly 50% discontinued AEDs within six months. Compared with non-users, AED users had an increased relative risk of death (IPTW hazard ratio (HR): 1.23; 95% CI: 1.12‒1.36). This was mainly due to deaths from dementia (IPTW HR: 1.62, 95% CI: 1.42‒1.86). There was no difference in cardio- and cerebrovascular deaths (IPTW HR: 0.98, 95% CI: 0.67‒1.44). The overall mortality was highest during the first 90 days of AED use (IPTW HR: 2.40, 95% CI: 1.91‒3.03). Among users of older AEDs relative risk of death was greater compared to users of newer AED use (IPTW HR: 1.79, 95% CI: 1.52‒2.16). Conclusions: In old vulnerable population with cognitive disorder, careful consideration of AED initiation and close adverse events monitoring are needed.