In 2021, the majority of social shoppers in Indonesia discovered a product or brand through search engines, accounting for ** percent of social shoppers. Social commerce has become a popular form of e-commerce in Indonesia in recent years.

Book Discovery Platforms Market Outlook

According to our latest research, the global Book Discovery Platforms market size reached USD 2.14 billion in 2024, driven by the proliferation of digital reading and the increasing integration of artificial intelligence in content curation. The market is expected to expand at a CAGR of 13.2% from 2025 to 2033, ultimately reaching USD 6.14 billion by 2033. The primary growth factor fueling this expansion is the rising demand for personalized book recommendations and seamless content accessibility across multiple digital touchpoints.

A significant driver of the Book Discovery Platforms market is the rapid digital transformation within the publishing and reading ecosystem. As consumers increasingly shift to digital reading formats, platforms that offer sophisticated discovery tools—such as AI-driven recommendation engines, advanced search functionalities, and user-friendly interfaces—are becoming essential. The integration of machine learning algorithms allows these platforms to analyze user preferences, reading history, and social interactions, delivering highly personalized book suggestions. This not only enhances user engagement but also supports publishers and authors in reaching targeted audiences more effectively, thereby fueling the overall growth of the market.

Another crucial growth factor is the diversification of platform types and the expansion of user demographics. Book Discovery Platforms are no longer limited to web-based portals; they now encompass mobile apps, integrated e-readers, and even social media platforms. This multi-channel approach caters to a broader audience, including individual readers, libraries, educational institutions, and publishers. The ability to access book recommendations and reviews on-the-go or within specialized communities has significantly increased user adoption. Furthermore, the development of interactive and community-driven features—such as book clubs, reading challenges, and peer reviews—has created vibrant ecosystems that encourage continuous user participation.

The evolution of monetization strategies has also played a pivotal role in the marketÂ’s growth trajectory. Book Discovery Platforms are leveraging a mix of subscription-based, advertisement-based, and freemium revenue models to maximize their reach and profitability. Subscription services offer premium features, ad-free experiences, and early access to new releases, while freemium models attract a wide user base with basic functionalities and upsell advanced features. Advertisement-based models, on the other hand, enable platforms to monetize high traffic volumes through targeted ads, sponsored content, and affiliate partnerships. The flexibility in revenue generation ensures sustainable growth and enables platforms to continually invest in technological innovation and content expansion.

In the realm of digital reading, Book Summary Apps have emerged as a valuable tool for readers seeking to maximize their literary consumption in a time-efficient manner. These apps provide concise summaries of popular books, enabling users to grasp key insights and themes without committing to the entire text. This trend aligns with the growing demand for personalized and accessible content, as readers increasingly seek ways to integrate learning into their busy schedules. By offering curated summaries, these apps complement traditional book discovery platforms, enhancing the overall reading experience and broadening the reach of authors and publishers.

From a regional perspective, North America continues to dominate the Book Discovery Platforms market, accounting for the largest share in 2024, followed by Europe and Asia Pacific. The robust digital infrastructure, high internet penetration, and strong presence of leading technology and publishing companies in North America have contributed to its leadership. However, Asia Pacific is witnessing the fastest growth, driven by increasing smartphone adoption, rising literacy rates, and a burgeoning middle-class population eager for diverse reading options. This regional dynamism is expected to reshape the competitive landscape and foster new opportunities for market players globally.

TikTok Advertising Agency Market Outlook

According to our latest research, the global TikTok Advertising Agency market size reached USD 2.4 billion in 2024 and is projected to grow at a robust CAGR of 17.8% during the forecast period, reaching USD 6.6 billion by 2033. The growth of the TikTok Advertising Agency market is primarily driven by the rapid adoption of short-form video content, the platform’s expanding user base, and the increasing demand for highly targeted and data-driven advertising solutions across diverse industry verticals.

A core growth factor fueling the TikTok Advertising Agency market is the platform’s unparalleled reach among Gen Z and Millennial audiences. TikTok’s unique algorithm, which enables highly personalized content discovery, has made it the preferred destination for brands seeking to engage younger demographics. As a result, agencies specializing in TikTok advertising are in high demand to craft compelling campaigns, manage influencer collaborations, and optimize ad spend for maximum ROI. The constant evolution of TikTok’s ad formats, including in-feed ads, branded hashtag challenges, and shoppable content, further incentivizes brands to partner with expert agencies that can navigate the platform’s dynamic landscape and deliver measurable outcomes.

Another significant driver is the surge in video-centric digital marketing budgets. Brands are increasingly shifting resources from traditional media to digital platforms, with TikTok emerging as a focal point due to its exceptional engagement rates and viral potential. TikTok advertising agencies are capitalizing on this trend by offering end-to-end campaign management, creative content development, and advanced analytics services. These agencies leverage TikTok’s sophisticated targeting capabilities, data analytics, and influencer networks to deliver campaigns that resonate with target audiences and drive brand awareness, customer acquisition, and sales growth. This shift toward performance-driven advertising is expected to sustain the market’s rapid expansion in the coming years.

The proliferation of e-commerce and direct-to-consumer brands is also propelling the TikTok Advertising Agency market. As more businesses seek to establish a digital-first presence, TikTok has become a critical channel for product launches, brand storytelling, and consumer engagement. Agencies are playing a pivotal role in helping brands leverage TikTok’s interactive features, such as live streaming and augmented reality filters, to create immersive shopping experiences. The integration of TikTok with e-commerce platforms and payment gateways further enhances the platform’s value proposition, driving demand for specialized agency services that can deliver seamless, conversion-focused campaigns.

From a regional perspective, Asia Pacific dominates the TikTok Advertising Agency market, accounting for the largest share in 2024, followed by North America and Europe. The rapid adoption of TikTok in countries like China, India, Indonesia, and Japan, coupled with the region’s vibrant digital ecosystem, has spurred significant investments in influencer marketing and creative content production. North America, led by the United States, is witnessing accelerated growth as brands allocate larger budgets to TikTok advertising, while Europe’s market is characterized by increasing regulatory scrutiny and evolving privacy standards. The Middle East & Africa and Latin America are emerging as high-potential markets, driven by rising smartphone penetration and the growing popularity of short-form video content among urban youth.

Service Type Analysis

The TikTok Advertising Agency market is segmented by service type into Campaign Management, Content Creation, Influencer Marketing, Analytics & Reporting, Account Management, and Others. Campaign Management remains the cornerstone of agency offerings, encompassing strategy development, audience targeting, budget allocation, and performance optimizat

CRISPR gene editing strategies are shaping cell therapies through precise and tunable control over gene expression. However, limitations in safely delivering high quantities of CRISPR machinery demand careful target gene selection to achieve reliable therapeutic effects. Informed target gene selection requires a thorough understanding of the involvement of target genes in gene regulatory networks (GRNs) and thus their impact on cell phenotype. Effective decoding of these complex networks has been achieved using machine learning models, but current techniques are limited to single cell types and focus mainly on transcription factors, limiting their applicability to CRISPR strategies. To address this, we present CRISPR-GEM, a multilayer perceptron (MLP) based synthetic GRN constructed to accurately predict the downstream effects of CRISPR gene editing. First, input and output nodes are identified as differentially expressed genes between defined experimental and target cell/tissue types, respectively. Then, MLP training learns regulatory relationships in a black-box approach allowing accurate prediction of output gene expression using only input gene expression. Finally, CRISPR-mimetic perturbations are made to each input gene individually, and the resulting model predictions are compared to those for the target group to score and assess each input gene as a CRISPR candidate. The top scoring genes provided by CRISPR-GEM therefore best modulate experimental group GRNs to motivate transcriptomic shifts toward a target group phenotype. This machine learning model is the first of its kind for predicting optimal CRISPR target genes and serves as a powerful tool for enhanced CRISPR strategies across a range of cell therapies.

The global Pay-Per-Click (PPC) advertising services market is experiencing robust growth, driven by the increasing adoption of digital marketing strategies across diverse sectors. The market's expansion is fueled by the need for businesses to enhance their online visibility, target specific customer segments effectively, and measure campaign performance accurately. E-commerce, with its reliance on targeted advertising for product discovery and sales conversion, is a significant driver, along with the hospitality and travel industries, which leverage PPC to reach potential customers searching for flights, hotels, and travel packages. Other key application segments such as real estate, education, healthcare, and financial services are also contributing significantly to market growth, adopting PPC for lead generation and brand awareness initiatives. The diverse types of PPC advertising, including search advertising, display advertising, shopping ads, video ads, and social media advertising, offer businesses flexibility in choosing the most effective channels to reach their target audience. While data privacy concerns and increasing advertising costs present some restraints, ongoing technological advancements and the emergence of sophisticated PPC management tools are mitigating these challenges. We estimate the 2025 market size to be around $150 billion, considering the growth trajectory of the digital marketing landscape and the consistent increase in online advertising spending. A conservative CAGR of 12% is projected for the forecast period (2025-2033), indicating a substantial market expansion. The competitive landscape is characterized by a mix of large, established agencies and specialized boutiques. Leading players are constantly innovating to offer comprehensive PPC management services, including campaign optimization, data analytics, and creative development. The geographical distribution of the market is widespread, with North America and Europe currently dominating the market share. However, significant growth opportunities exist in emerging markets across Asia-Pacific, Latin America, and the Middle East & Africa, driven by increasing internet penetration and digital literacy. This geographical diversity necessitates a tailored approach to PPC strategy, acknowledging variations in consumer behavior, digital infrastructure, and regulatory environments. The increasing demand for specialized PPC services will likely lead to further market consolidation and specialization, with agencies focusing on specific niches or industry verticals. The continued evolution of search engine algorithms, social media platforms, and advertising technologies will necessitate continuous adaptation and innovation from service providers to maintain their competitive edge.

Despite being an old molecule, capsaicin is still a hot topic in the scientific community, and the development of new capsaicinoids is a promising pharmacological approach in the management of skin disorders related to inflammation and pruritus. Here we report the synthesis and the evaluation of capsaicin soft drugs that undergo deactivation by the hydrolyzing activity of skin esterases. The implanting of an ester group in the lipophilic moiety of capsaicinoids by the Passerini multicomponent reaction affords both agonists and antagonists that retain transient receptor potential vanilloid 1 channel (TRPV1) modulating activity and, at the same time, are susceptible to hydrolysis. The most promising antagonist identified shows in vivo anti-nociceptive activity on pruritus and hyperalgesia without producing hyperthermia, thus validating it as novel treatment for dermatological conditions that implicate TRPV1 channel dysfunction.

ND - Not determined; all study participants were challenged with cat allergen.a: geometric mean (PC20 values are measured on a log scale);b: [PC20]pre/[PC20]post.cp