The expiring and deleted domains statistics cover both generic top-level domains (gTLDs) and country-code top-level domains (ccTLDs). This dataset helps you stay up to date and make data-driven decisions in the domain industry based on daily updates.

Employment statistics on the Web Domain Name Sales industry in the US

Comprehensive collection of Norwegian .no domain names with associated subdomain information, DNSSEC security data, and domain intelligence

As of August 2024, the most popular new generic top-level domain (gTLD) was .xyz with approximately 4.16 million domains, accounting for16.71 percent of gTLDs. The second-most popular gTLD was .online with 3.63 million registrations. Domains that do not have a country or geographic designation are often referred to by the term generic TLDs.

As of July 2023, China's .cn was the most popular country code top-level domain (ccTLD) worldwide with approximately 32.41 million registrations. Tokelau's .tk was ranked second with 27.54 million registered domains. During the measured period there were approximately 300 million domains registered to country TLDs.

As of August 2024, 44.4 percent of global websites used a .com top-level domain. The .org TLD was ranked second with a 425 percent market share. The domain name is a component of a uniform resource locator (URL) used to access web pages.

The STAT protein (Signal Transducers and Activators of Transcription) family contains transcription factors that are specifically activated to regulate gene transcription when cells encounter cytokines and growth factors, hence they act as signal transducers in the cytoplasm and transcription activators in the nucleus . Binding of these factors to cell-surface receptors leads to receptor autophosphorylation at a tyrosine, the phosphotyrosine being recognised by the STAT SH2 domain, which mediates the recruitment of STAT proteins from the cytosol and their association with the activated receptor. The STAT proteins are then activated by phosphorylation via members of the JAK family of protein kinases, causing them to dimerise and translocated to the nucleus, where they bind to specific promoter sequences in target genes. In mammals, STATs comprise a family of seven structurally and functionally related proteins: Stat1, Stat2, Stat3, Stat4, Stat5a and Stat5b, Stat6. STAT proteins play a critical role in regulating innate and acquired host immune responses. Dysregulation of at least two STAT signalling cascades (i.e. Stat3 and Stat5) is associated with cellular transformation.Signalling through the JAK/STAT pathway is initiated when a cytokine binds to its corresponding receptor. This leads to conformational changes in the cytoplasmic portion of the receptor, initiating activation of receptor associated members of the JAK family of kinases. The JAKs, in turn, mediate phosphorylation at the specific receptor tyrosine residues, which then serve as docking sites for STATs and other signalling molecules. Once recruited to the receptor, STATs also become phosphorylated by JAKs, on a single tyrosine residue. Activated STATs dissociate from the receptor, dimerise, translocate to the nucleus and bind to members of the GAS (gamma activated site) family of enhancers.The seven STAT proteins identified in mammals range in size from 750 and 850 amino acids. The chromosomal distribution of these STATs, as well as the identification of STATs in more primitive eukaryotes, suggest that this family arose from a single primordial gene. STATs share 6 structurally and functionally conserved domains including: an N-terminal domain (ND) that strengthens interactions between STAT dimers on adjacent DNA-binding sites; a coiled-coil STAT domain (CCD) that is implicated in protein-protein interactions; a DNA-binding domain (DBD) with an immunoglobulin-like fold similar to p53 tumour suppressor protein; an EF-hand-like linker domain connecting the DNA-binding and SH2 domains; an SH2 domain ([interpro:IPR000980]) that acts as a phosphorylation-dependent switch to control receptor recognition and DNA-binding; and a C-terminal transactivation domain . The crystal structure of the N terminus of Stat4 reveals a dimer. The interface of this dimer is formed by a ring-shaped element consisting of five short helices. Several studies suggest that this N-terminal dimerisation promotes cooperativity of binding to tandem GAS elements and with the transcriptional coactivator CBP/p300.

STAT proteins (Signal Transducers and Activators of Transcription) are a family of transcription factors that are specifically activated to regulate gene transcription when cells encounter cytokines and growth factors. This family represents the DNA binding domain of STAT, which has an ig-like fold. STAT proteins also include an SH2 domain [pfam:PF00017].

Fabulous is a leading domain name registrar and developer of domain management tools. Founded by domainers for domainers, Fabulous offers competitive pricing on domain registration services, making it one of the world's cheapest registrars for professional domain owners. The company provides a comprehensive platform for domain registration, renewal, and transfer, including Whois privacy, domain monetization, parking management, and integrated sales channels.

Fabulous also offers premium services such as a built-in sales network, parking program, and full reporting features. The company's domain management system is designed to help domainers maximize performance and financial return, with features such as bulk management tools, click tracking, and statistics reporting. With Fabulous, domain owners can register, manage, and monetize their domains effectively, making it an ideal choice for those in the domain industry.

National Domain Name (DN) Registration Quantity Statistics Table

STAT proteins (Signal Transducers and Activators of Transcription) are a family of transcription factors that are specifically activated to regulate gene transcription when cells encounter cytokines and growth factors. STATs share 6 structurally and functionally conserved domains including: an N-terminal domain (ND) that strengthens interactions between STAT dimers on adjacent DNA-binding sites; a coiled-coil STAT domain (CCD) that is implicated in protein-protein interactions; a DNA-binding domain (DBD) with an immunoglobulin-like fold similar to p53 tumour suppressor protein; an EF-hand-like linker domain connecting the DNA-binding and SH2 domains; an SH2 domain that acts as a phosphorylation-dependent switch to control receptor recognition and DNA-binding; and a C-terminal transactivation domain. This entry represents the coiled-coil domain (CCD)

Cleaned Newly Registered Domain names Count offers an up-to-date overview of newly registered domains, including both generic top-level domains (gTLDs) and country-code top-level domains (ccTLDs). Stay up-to-dated and make data-driven decisions in the domain industry with our regularly updated dataset.

Gross domestic product, output and jobs for sport and culture, product perspective, quarterly.

General Newly Registered Domains Count provides a comprehensive record of newly registered domains across different zones, encompassing both generic top-level domains (gTLDs) and country-code top-level domains (ccTLDs). Updated daily to include today's count, this dataset offers valuable insights into the evolving domain registration landscape. Whether you're tracking market trends or conducting research, our dataset equips you with the latest information to make informed decisions in the domain industry.

Specific Newly Registered Domains Count provides an up-to-date overview of newly registered domains, including both generic top-level domains (gTLDs) and country-code top-level domains (ccTLDs). Stay informed and make data-driven decisions in the domain industry with our regularly updated dataset, focusing on TLDs and ccTLDs.

This statistic illustrates the number of Internet domain name registrations in Spain in December 2019, by domain name type. During this period, the domain '.es' was ranked first with approximately *** million registrations. It was followed by '.com.es', which had over ** million registrations.

Introduction

Website Statistics: The internet landscape is constantly evolving, and understanding the dynamics of website development and browser usage is crucial for businesses and individuals alike. In 2024, the web design and development industry has grown significantly, driven by increased demand for innovative and responsive web solutions. Major browsers like Google Chrome, Safari, and Microsoft Edge dominate the market, each offering unique features that cater to diverse user needs.

This article delves into the latest statistics, market shares, and technological trends in the web development and browser domains, providing valuable insights to help you navigate the digital world effectively.

This table lists total number of links and broken links (HTTP status codes 3xx, 4xx, and 5xx) to top domains (domains with over 100 links) found within articles published in the four main astronomy journals between 1997 and 2008. The table also shows, for each domain, the portion of links to common filename extensions, as well as links that contain the tilde character.Some descriptive statistics about top domains linked in astronomy publications.

In 2024, the World Intellectual Property Organization (WIPO) received 1929 cybersquatting cases. The total number of domain names was over 4,000 domain names. The number of cases filed to the World Intellectual Property Organization had increased, especially since 2012, when there were around, 2900 such disputes.

Business Software Alliance is a trade association that represents the world's leading software companies, including Autodesk, IBM, and Symantec. The organization's members are committed to promoting the use of legitimate software and ensuring the integrity of their intellectual property.

As a result, the data housed on BSA's website is rich in information related to the software industry, including software licensing, anti-piracy efforts, and digital piracy statistics. The data includes information on software usage, software development, and the impact of piracy on the technology industry. With its focus on promoting legitimate software use, the data on BSA's website provides valuable insights into the global software industry.