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100+ datasets found
  1. e

    Dopamine receptor family

    • www.ebi.ac.uk
    Updated Jul 1, 2006
  2. R

    Dopamine Neurotransmitter Release Cycle

    • reactome.org
    sbgn, biopax2, pdf +4
  3. e

    Dopamine D4 receptor

    • www.ebi.ac.uk
    Updated Nov 20, 2015
  4. e

    Dopamine D5 receptor

    • www.ebi.ac.uk
    Updated Apr 27, 2013
  5. H

    'Unilateral lesion of dopamine neurons induces grooming asymmetry in the...

    • dataverse.harvard.edu
    mp4, tsv
    Updated May 30, 2015
  6. R

    Dopamine Neurotransmitter Release Cycle

    • reactome.org
    biopax2, sbgn, pdf +4
  7. d

    Data from: The influence of dopamine on cognitive flexibility is mediated by...

    • datadryad.org
    • search.datacite.org
    zip
    Updated May 24, 2018
  8. N

    Data from: Individual differences in dopamine are associated with reward...

    • neurovault.org
    zip
    Updated Nov 18, 2018
  9. Supplementary Material for: MicroRNA-128 Protects Dopamine Neurons from...

    • dx.doi.org
    • karger.figshare.com
    Updated Dec 7, 2018
  10. Voltammetry, food intake and body weight data (Protein restriciton and...

    • leicester.figshare.com
    zip
    Updated Jun 10, 2020
  11. e

    D2-like dopamine receptors, member of the class A family of...

    • www.ebi.ac.uk
    Updated Nov 20, 2020
  12. R

    Dopamine receptors

    • www.reactome.org
    biopax2, sbgn, pdf +4
    Updated Mar 3, 2009
  13. t

    BIOGRID CURATED DATA FOR PUBLICATION: Stimulation of dopamine receptors in...

    • thebiogrid.org
    zip
  14. R

    Dopamine clearance from the synaptic cleft

    • reactome.org
    biopax2, sbgn, pdf +4
  15. e

    Dopamine D2 receptor

    • www.ebi.ac.uk
    Updated Oct 13, 2020
  16. Optogenetic Mimicry of the Transient Activation of Dopamine Neurons by...

    • plos.figshare.com
    qt, pdf
    Updated Jan 19, 2016
  17. N

    The Influence of Dopamine on Cognitive Flexibility Is Mediated by Functional...

    • neurovault.org
    nifti
    Updated Jun 30, 2018
  18. e

    Data from: Dopamine D1 receptor

    • www.ebi.ac.uk
    Updated Nov 20, 2015
  19. e

    D2 subtype of the D2-like family of dopamine receptors, member of the class...

    • www.ebi.ac.uk
    Updated Mar 12, 2020
  20. Summary of event-related temporal changes of dopamine-like component.

    • plos.figshare.com
    xls
    Updated Dec 3, 2015
  21. f

    Table_1_Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic...

    • frontiersin.figshare.com
    doc
    Updated Jul 11, 2019
  22. d

    Data from: D2 dopamine receptor activation induces female preference for...

    • datadryad.org
    zip
    Updated Feb 12, 2019
  23. d

    Data from: Reward-induced phasic dopamine release in the monkey ventral...

    • datadryad.org
    zip
    Updated Jul 1, 2015
  24. o

    Yapo2017- cAMP/PKA signalling in D1 dopamine receptor expressing...

    • www.omicsdi.org
    xml
  25. Estradiol increases the sensitivity of ventral tegmental area dopamine...

    • plos.figshare.com
    tiff
    Updated Nov 7, 2017
  26. o

    Nucleus accumbens core dopamine during Go-NoGo task

    • data.mrc.ox.ac.uk
    Updated 2018
  27. e

    Data from: Histamine H3 receptor

    • www.ebi.ac.uk
    • orchidbase.itps.ncku.edu.tw
    Updated Sep 30, 2019
  28. R

    Dopamine is oxidised to noradrenaline

    • reactome.org
    sbgn, biopax2, pdf +4
  29. f

    Dopamine Neurons Change the Type of Excitability in Response to Stimuli

    • plos.figshare.com
    ai, docx
    Updated Dec 9, 2016
  30. w

    Dopamine

    • bmrb.wisc.edu
    Updated Dec 19, 2017
  31. t

    BIOGRID CURATED DATA FOR PUBLICATION: Extracellular serotonin, dopamine and...

    • thebiogrid.org
    zip
    Updated Jul 1, 2004
  32. R

    Dopamine is oxidised to noradrenaline

    • reactome.org
    sbgn, pdf, biopax2 +4
  33. R

    Dopamine receptors

    • reactome.org
    pdf, biopax2, sbgn +4
  34. R

    Enzymatic degradation of Dopamine by monoamine oxidase

    • reactome.org
    pdf, sbgn, biopax2 +4
  35. R

    Enzymatic degradation of dopamine by COMT

    • www.reactome.org
    sbgn, pdf, biopax2 +4
  36. R

    Dopa is decarboxylated to dopamine

    • reactome.org
    sbgn, biopax2, pdf +4
  37. d

    Data from: Vesicular monoamine transporter 2 (VMAT2) level regulates MPTP...

    • datadryad.org
    zip
    Updated May 26, 2016
  38. Data from: Ligand Binding Pathways of Clozapine and Haloperidol in the...

    • acs.figshare.com
    zip
    Updated Feb 16, 2016
  39. N

    Individual differences in dopamine are associated with reward discounting in...

    • neurovault.org
    nifti
    Updated Nov 18, 2018
  40. Reward-Induced Phasic Dopamine Release in the Monkey Ventral Striatum and...

    • plos.figshare.com
    tiff, pdf, doc
    Updated Jan 15, 2016
  41. d

    Dopaminergic mechanisms underlying normal variation in trait anxiety:...

    • datadryad.org
    • search.datacite.org
    zip
    Updated Sep 5, 2018
  42. t

    BIOGRID CURATED DATA FOR PUBLICATION: An Akt/beta-arrestin 2/PP2A signaling...

    • thebiogrid.org
    zip
    Updated Jul 29, 2005
  43. e

    Dopamine D3 receptor

    • www.ebi.ac.uk
    Updated Mar 4, 2020
  44. d

    Data from: Modulation of social space by dopamine in Drosophila...

    • datadryad.org
    zip
    Updated Jul 20, 2017
  45. f

    Data_Sheet_1_Dopamine and Dopamine Receptors in Alzheimer's Disease: A...

    • figshare.com
    doc
    Updated Jul 11, 2019
  46. e

    Tyramine beta-hydroxylase/Dopamine beta-hydroxylase

    • www.ebi.ac.uk
  47. Activation of RHO-1 in cholinergic motor neurons competes with dopamine...

    • plos.figshare.com
    mp4, ai, m4v, docx
    Updated Sep 21, 2018
  48. R

    Dopamine is oxidised to noradrenaline

    • reactome.org
    biopax2, sbgn, pdf +4
  49. Spatial extent of estimated dopamine release induced by THC within striatal...

    • plos.figshare.com
    xls
    Updated Dec 2, 2015
  50. Data from: Raw data for Trujillo-Pisanty, I., Conover, K., Solis, P.,...

    • spectrum.library.concordia.ca
    zip
    Updated 2020
  51. N

    Data from: Dissociable Roles of Cerebral μ-Opioid and Type 2 Dopamine...

    • neurovault.org
    zip
    Updated Jun 30, 2018
  52. Suppression of Dopamine Neurons Mediates Reward

    • figshare.com
    xlsx, tiff, docx
    Updated Dec 21, 2016
  53. d

    Transactivation of the dopamine receptor 3 gene results in development of...

    • datamed.org
    Updated Mar 10, 2010
  54. t

    BIOGRID CURATED DATA FOR PUBLICATION: Dopamine D1 receptor agonist and D2...

    • thebiogrid.org
    zip
    Updated May 2, 2007
  55. d

    Whole-organism behavioral profiling reveals a role for dopamine in...

    • datadryad.org
    zip
    Updated Jul 15, 2020
  56. /

    Data for: Functional gene expression of dopamine receptors in the male...

    • data.mendeley.com
    • search.datacite.org
    Updated Nov 26, 2018
  57. f

    DARPP-32 Is a Robust Integrator of Dopamine and Glutamate Signals

    • figshare.com
    xml
    Updated Jan 18, 2016
  58. t

    BIOGRID CURATED DATA FOR PUBLICATION: The Detection of Dopamine Gene...

    • thebiogrid.org
    zip
    Updated Dec 1, 2004
  59. Dopamine receptor antagonists as potential therapeutic agents for ADPKD

    • plos.figshare.com
    pdf, tiff
    Updated May 6, 2019
  60. t

    BIOGRID CURATED DATA FOR PUBLICATION: KLHL12 Promotes Non-Lysine...

    • thebiogrid.org
    zip
    Updated Dec 31, 2015
  61. Inhibition of α-Synuclein Fibrillization by Dopamine Is Mediated by...

    • figshare.com
    pdf, tiff, doc
    Updated Jan 18, 2016
  62. Supplementary Material for: Expression of Dopamine Receptors in Immune...

    • karger.figshare.com
    • search.datacite.org
    pdf, docx
    Updated Jul 16, 2019
  63. t

    BIOGRID CURATED DATA FOR PUBLICATION: 5-HT2 antagonists and minaprine block...

    • thebiogrid.org
    zip
    Updated Sep 4, 2004
  64. R

    Enzymatic degradation of Dopamine by monoamine oxidase

    • reactome.org
    biopax2, pdf, sbgn +4
  65. Data from: D2 dopamine receptor activation induces female preference for...

    • www.narcis.nl
    • search.datacite.org
    Updated Feb 12, 2019
  66. Season of Birth and Dopamine Receptor Gene Associations with Impulsivity,...

    • plos.figshare.com
    doc, xls
    Updated Jan 18, 2016
  67. e

    Protein phosphatase 1 regulatory subunit 1B

    • www.ebi.ac.uk
    Updated Nov 20, 2015
  68. d

    Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene...

    • datamed.org
    Updated Feb 5, 2013
  69. [Rn00562768_s1] [Drd5]

    • www.thermofisher.com
    Updated Jul 10, 2017
  70. Data from: Subtype Selectivity of Dopamine Receptor Ligands: Insights from...

    • acs.figshare.com
    zip
    Updated Feb 24, 2016
  71. d

    Data from: Genetic polymorphism in dopamine receptor D4 is associated with...

    • datamed.org
    • dryad-stg.cdlib.org
    • +3more
  72. [Mm00438541_m1] [Drd2]

    • www.thermofisher.com
    Updated Jul 31, 2018
  73. t

    BIOGRID CURATED DATA FOR PUBLICATION: The Caenorhabditis elegans D2-like...

    • thebiogrid.org
    zip
    Updated Jan 28, 2012
  74. o

    Yapo2017 - A2AR/cAMP/PKA signalling in D2 dopamine receptor expressing...

    • www.omicsdi.org
    xml
  75. Modulation of Bleomycin-Induced Lung Fibrosis by Pegylated Hyaluronidase and...

    • plos.figshare.com
    pdf, tiff
    Updated Jan 15, 2016
  76. The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine...

    • plos.figshare.com
    pdf, mpeg
    Updated Jan 18, 2016
  77. Data from: Stimulation of dopamine D1 receptor improves learning capacity in...

    • www.narcis.nl
    • search.datacite.org
    Updated Dec 14, 2015
  78. Methamphetamine and Dopamine Receptor D1 Regulate Entrainment of Murine...

    • plos.figshare.com
    tiff, docx
    Updated Jan 18, 2016
  79. The Role of Dopamine in Drosophila Larval Classical Olfactory Conditioning

    • figshare.com
    tiff
    Updated Jan 18, 2016
  80. a

    drd2a

    • www.alliancegenome.org
    Updated Aug 27, 2020
  81. An Autonomous Circadian Clock in the Inner Mouse Retina Regulated by...

    • plos.figshare.com
    tiff
    Updated Jan 18, 2016
  82. d

    BindingDB Entry 4838: Risperidone: a novel antipsychotic with balanced...

    • search.datacite.org
    Updated 2011
  83. R

    Loading of dopamine into synaptic veiscles

    • reactome.org
    pdf, biopax2, sbgn +4
  84. t

    BIOGRID CURATED DATA FOR PUBLICATION: Dopamine receptor blockade increases...

    • thebiogrid.org
    zip
    Updated Sep 4, 2004
  85. Manipulating the revision of reward value during the intertrial interval...

    • plos.figshare.com
    xlsx, tiff
    Updated Oct 8, 2018
  86. AAV-shRNA mediates dopamine receptors silencing in vivo.

    • figshare.com
    tiff
    Updated Feb 24, 2016
  87. Dopamine levels after 6-OHDA-lesions and noradrenaline levels after DSP-4...

    • plos.figshare.com
    xls
    Updated Dec 2, 2015
  88. t

    BIOGRID CURATED DATA FOR PUBLICATION: Protein kinase C and intracellular...

    • thebiogrid.org
    zip
    Updated Jun 1, 2001
  89. t

    BIOGRID CURATED DATA FOR PUBLICATION: Binding of losartan to angiotensin AT1...

    • thebiogrid.org
    zip
    Updated Dec 22, 2011
  90. Dopamine Increases CD14+CD16+ Monocyte Migration and Adhesion in the Context...

    • plos.figshare.com
    tiff, avi
    Updated Jan 15, 2016
  91. N

    Dissociable Roles of Cerebral μ-Opioid and Type 2 Dopamine Receptors in...

    • neurovault.org
    nifti
    Updated Jun 30, 2018
  92. f

    Table_1_D1 Dopamine Receptor Activation Induces Neuronal eEF2...

    • figshare.com
    docx
    Updated May 15, 2020
  93. a

    drd1b

    • www.alliancegenome.org
    Updated Aug 27, 2020
  94. f

    Transient Calcium and Dopamine Increase PKA Activity and DARPP-32...

    • plos.figshare.com
    tiff
    Updated Jan 18, 2016
  95. t

    BIOGRID CURATED DATA FOR PUBLICATION: Dual activation by lisuride of central...

    • thebiogrid.org
    zip
    Updated Sep 4, 2004
  96. H

    Replication Data for: Brief Exposure to Obesogenic Diet Disrupts Brain...

    • dataverse.harvard.edu
    zip, txt
    Updated Aug 11, 2017
  97. f

    Data_Sheet_2_Kv7.4 Channel Contribute to Projection-Specific Auto-Inhibition...

    • figshare.com
    pdf
    Updated Dec 18, 2019
  98. BindingDB Entry 50017605: Dopamine/serotonin receptor ligands. 12(1): SAR...

    • search.datacite.org
    Updated 2009
  99. Peri-Pubertal Emergence of UNC-5 Homologue Expression by Dopamine Neurons in...

    • plos.figshare.com
    tiff
    Updated Jan 18, 2016
  100. a

    drd2b

    • www.alliancegenome.org
    Updated Aug 27, 2020
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(2006) Dopamine receptor family. [Dataset] https://www.ebi.ac.uk/interpro/entry/IPR000929

Dopamine receptor family

Dataset updated Jul 1, 2006
License

Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically

Description

Dopamine receptors are members of the rhodopsin-like G-protein coupled receptor family and are prominent in the vertebrate central nervous system (CNS). Dysfunction of dopaminergic neurotransmission in the CNS has been implicated in a variety of neuropsychiatric disorders , including social phobia , Tourette's syndrome , Parkinson's disease , schizophrenia , neuroleptic malignant syndrome , attention-deficit hyperactivity disorder (ADHD) and drug and alcohol dependence . As a result, dopamine receptors are common drug targets; antipsychotics are often dopamine receptor antagonists while psychostimulants are typically indirect agonists of dopamine receptors .There are at least five different known subtypes of dopamine receptors designated D1, D2, D3, D4 and D5 . They are distinguished by their G-protein coupling, ligand specificity, anatomical distribution and physiological effects. Dopamine receptors are divided into two further subfamilies. The D1-like family consists of D1 and D5 receptors, which couple to Gs and mediate excitatory neurotransmission. The D2-like family, meanwhile, consists of D2, D3 and D4 receptors, which couple to Gi/Go and mediate inhibitory neurotransmission. Although dopamine receptors are widely distributed in the brain, they are found in different locations that have different receptor type densities, presumably reflecting different functional roles . D1 and D2 receptor subtypes are found at 10-100 times the levels of the D3, D4, D5 subtypes .

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