From 1999 to 2023, the number of drug overdose deaths in the United States increased from 16,849 in 1999 to almost 105,007 in 2023. This statistic shows the number of drug overdose deaths in the United States from 1999 to 2023.

Introduction

Opioids Crisis Statistics: In recent years, the opioid crisis has emerged as a critical public health challenge, profoundly affecting communities across the globe. Characterized by a dramatic rise in opioid prescriptions, misuse, and overdose deaths, this epidemic has placed immense strain on healthcare systems and social services.

Statistical data reveals alarming trends, including escalating rates of opioid-related fatalities and hospitalizations, highlighting the urgent need for effective intervention strategies. Understanding these statistics is essential to grasp the scale of the crisis, identify vulnerable populations, and guide policymakers in implementing targeted prevention and treatment efforts.

In 2022, the drug overdose death rate for male adolescents in the U.S. was three per 100,000 adolescents. Between 2018 and 2022, the drug overdose death rate for adolescents in the United States more than doubled for males and females. This statistic illustrates the drug overdose death rate among adolescents in the United States from 2018 to 2022, by sex (per 100,000 adolescents).

In 2024, there were a total of 7,146 deaths in Canada due to opioid overdose, with around 28 percent of deaths occurring among those aged 30 to 39 years. This statistic shows the distribution of deaths from opioid overdose in Canada from 2016 to 2024, by age.

Find data on deaths of Massachusetts residents. Information is obtained from death certificates received by the Registry of Vital Records and Statistics.

In 2024, there were a total of 7,146 deaths in Canada due to opioid overdose, with around 71 percent of deaths occurring among males. This statistic shows the distribution of deaths from opioid overdose in Canada from 2016 to 2024, by gender.

In 2022, almost 46 men died from drug overdose per 100,000 population, a significant increase from the rate of 10.6 that was recorded in 2002. This statistic shows the death rate from drug overdose among men in the U.S. from 2002 to 2022, per 100,000 population.

Between June 2024 and May 2025, the rate of emergency department (ED) visits for fentanyl-involved nonfatal overdose in males was 3.5 per 10,000 ED visits. Meanwhile, the rate of ED visits for fentanyl-involved nonfatal overdose in females was 1.4 per 10,000 ED visits.

In 2023, the rate of suicide deaths in the United States was highest among American Indians and Alaska Natives with 23.8 deaths per 100,000 population. This statistic depicts the rate of alcohol, drug, and suicide deaths in the U.S. in 2023, by race/ethnicity.

From 2016 to 2022, the median total length of stay for opioid-related poisoning hospitalizations in Canada was three days. This statistic shows the median total length of stay of opioid-related poisoning hospitalizations in Canada from 2016 to 2022.

It is estimated that alcohol contributed to around 2.6 million deaths worldwide in 2019. The major causes of alcohol-related death include alcohol poisoning, liver damage, heart failure, cancer, and car accidents. Alcohol abuse worldwide Despite the widespread use of alcohol around the world, a global survey from 2024 of people from 31 different countries found that around 16 percent of respondents stated alcohol abuse was the biggest health problem facing people in their country. The countries with the highest per capita consumption of alcohol include Romania, Georgia, and Latvia. Alcohol consumption in the United States It is estimated that over half of adults in the United States aged 21 to 49 currently use alcohol. Binge drinking (four or more drinks for women and five or more drinks for men on a single occasion) is most common among those aged 21 to 29 years, but still around 25 percent of those aged 40 to 44 report binge drinking. The states with the highest share of the population who binge drink are North Dakota, Iowa, and South Dakota. The death rate due to alcohol in the United States was around 13.5 per 100,000 population in 2022, an increase from a rate of 10.4 per 100,000 recorded in 2019.

In 2022, around 34 percent of accidental opioid-related poisoning hospitalizations in Canada involved fentanyl or fentanyl analogues. This statistic shows the share of accidental opioid-related poisoning hospitalizations in Canada in 2022 that involved fentanyl or fentanyl analogues, by province.

In 2023, 263 men aged between 45 and 54 years died from drug-related causes in Scotland, the highest number of drug related deaths among men across all age groups. Meanwhile, there were 121 drug related deaths among women aged between 35 and 44 years, the highest number of deaths among women across all age groups.

In 2023, there were 1,172 drug-related deaths in Scotland. The number of drug-related deaths in Scotland was generally increasing from the years 2000 to 2021, before declining significantly in 2022.