In 2018, 92 people died as a result of MDMA/ecstasy use in England and Wales, this was by far the highest amount of recorded deaths in the 25-year period shown, while 79 deaths were recorded as a result of MDMA in 2023. Since the turn of the century, the number of deaths has remained relatively high apart from a drastic fall in 2010 and 2011 before subsequently rising again. Seriousness of MDMA offencesIn the United Kingdom (UK) MDMA is categorized as a class A drug which means it carries the most severe penalties for both possession and supply. In 2021/22, police in England and Police carried out almost 2.5 thousand seizures of ecstasy. This is approximately 70 percent fewer seizures compared to 2006/07. Comparisons with the EUThe Netherlands had the highest prevalence of ecstasy use in the EU at almost five percent admitting to using in a the last year as of 2022. The UK's closest neighbor, Ireland, ranked as having the second-highest reported use at 2.7 percent.

In 2023, it was estimated that around *** million people in the United States had used ecstasy, also known as MDMA or Molly, in the past year. MDMA is a synthetic drug that produces feelings of pleasure and emotional warmth, as well as increased empathy, energy, and sense of well-being. MDMA may also cause negative effects such as nausea, jaw clenching, chills, and disorganized thoughts, but deaths from MDMA overdose are rare. MDMA use in the United States As of 2023, around **** million people in the United States had used MDMA at some point in their lifetime. Furthermore, around *** thousand people reported using MDMA in the past month. Although MDMA gained popularity as a club drug, it is now used by a wider range of people for different reasons. However, it’s use among high school students is still relatively rare. As of 2023, only *** percent of U.S. students in grades 8, 10, and 12 reported that they had used MDMA in their lifetime. In comparison, around **** percent of students said they had used marijuana in their lifetime. MDMA as therapy In recent years there has been increased interest in using psychedelic drugs such as MDMA, LSD, and psilocybin to treat mental disorders. The use of these substances for mental health treatment is known as psychedelic therapy. Clinical trials are now being run to investigate the use of MDMA to treat post-traumatic stress disorder (PTSD), depression, anxiety, and alcohol use disorder. From 2000 to 2022, there were ** clinical trials worldwide in phase two involving MDMA to treat PTSD.

Deaths related to drug poisoning in England and Wales by cause of death, sex, age, substances involved in the death, geography and registration delay.

Annual number of deaths registered related to drug poisoning in England and Wales by sex, region and whether selected substances were mentioned anywhere on the death certificate, with or without other drugs or alcohol, and involvement in suicides.

This statistic shows the amount of ecstasy-type drug-related deaths reported to NPSAD in England in 2012, by age group. Statistically, people aged between 15 and 24 years were the most likely to have had an ecstasy-type drug-related death. It is important to note that these deaths may also have involved other implicated psychoactive substances that are not detailed here.

This dataset is about books. It has 4 rows and is filtered where the book is Death in ecstasy. It features 4 columns: author, book publisher, and BNB id.

In 2021, there were 298 drug overdose deaths were recorded in the Netherlands. The number of casualties was lowest in 2010, while 2021 represented the highest annual figure. In the last two years, a new record in drug deaths was reached.

 Opiates, cocaine and other dangerous drugs 

Many drug deaths in the Netherlands in 2021 were caused by opiates. Of the total 298 casualties in 2021, 150 died because of opiate use. By comparison, there were 72 cocaine deaths that year. This is also the highest number of cocaine-related deaths in the country in the past decade.

Cocaine use on the rise

 According to the Trimbos survey on drug use, cocaine use has increased in the Netherlands. Whereas in 1997, 2.6 percent of the respondents stated to have used cocaine at least once in their lives, by 2021 this had grown to 6.5 percent. Of the survey participants, 0.8 percent reported to have used cocaine in the past month, a slight change in comparison to earlier years as well.

This statistic displays the share of respondents who used ecstasy in the Netherlands from 1997 to 2022, by frequency of use. In 1997, approximately *** percent of respondents reported to have used ecstasy at least once in their lives. By 2022, this had increased to over *** percent.

This dataset is about book series. It has 2 rows and is filtered where the books is Death in ecstasy. It features 4 columns: authors, books, and publication dates.

This statistic displays the total number of drug deaths in the Netherlands in 2022, by type. In that year, there were *** drug-related deaths in the Netherlands. Over half of these deaths were caused by opioids. Cocaine was responsible for another ** deaths.

Anxiety associated with life-threatening illness (LTI) is a pervasive mental health issue with a wide impact. A spectrum of traditional pharmacotherapies and psychotherapies are available, but offer varying success in reducing symptoms and improving quality of life. We explore a novel therapy for this condition by assessing prominent thematic elements from participant narrative accounts of a pilot phase 2 clinical trial of 3,4 Methylenedioxymethamphetamine-Assisted Therapy (MDMA-AT) for treating anxiety associated with LTI. Semi-structured qualitative interviews were conducted with a subset of adult participants 3 months following completion of this trial. This qualitative analysis sought to complement, clarify, and expand upon the quantitative findings obtained from the clinical trial to further understand the process and outcomes of the treatment. Interviews were coded and analyzed using an Interpretative Phenomenological Analysis (IPA) methodological framework. Participants described in detail their experiences from before, during and after the trial, which were analyzed and categorized into thematic clusters. Specifically, participants explored what they felt were important elements of the therapeutic process including processing trauma and grief, exploring mystical and existential experiences, engaging with the present moment with reduced physiological activation, and facing illness and existential fears. Outcomes of the treatment included increased ability to cope with LTI, reduced psychological symptoms, improved vitality and quality of life, and feeling more resourced. Participant narratives also showed a reconnection to life and greater emotional resilience in response to trauma and medical relapse. These findings are compared to similar treatments for the same indication. Limitations and challenges encountered in conducting this study are discussed along with implications for theory and clinical treatment.

Incremental costs, QALYs and cost-effectiveness: Phase 3 vs phase 2 regimen for 1,000 patients; 1, 5, 10, and 30-year analytic time horizons for 1,000 patients.

The Netherlands had the highest prevalence of ecstasy use among adults in Europe as of 2023, with approximately 4.8 percent of the population reported to using ecstasy. This was followed by Ireland with 2.7 percent of the population and then Czechia at 2.6 percent. Demographics of users in the Netherlands Among the younger age groups is where both frequent and infrequent users of ecstasy are found in the Netherlands. Almost 30 percent of those aged between 25 and 29 years have tried ecstasy at some point in their lives, as of a 2021 survey. While almost four percent in the same age group stated they had taken ecstasy in the past month. Use of other drugs in the EU Cannabis is by far the most used drug across the population of the European Union, with almost 30 using at some point during their lifetime. This is followed by cocaine, which reportedly five percent have used in their life and then MDMA with four percent of individuals having used. Additionally, cannabis was the most seized drug in Europe in 2023, with nearly 70 percent of all seizures being a form of cannabis.

In Germany, the illegal drugs with the highest street value were cocaine and heroin, with the former costing around **** euros per gram or consumption unit, and the latter **** euros in 2023. Ecstasy had the lowest price at *** euros per gram. Illegal drugs There is debate worldwide about whether drugs should be legal or not. Some experts say that legalizing drugs will help those who are addicted as they will not be forced to buy drugs on the black market where they are often mixed with other substances, making them extremely dangerous and often even lethal. However, others feel that keeping certain drugs illegal dissuades people from trying them. Different nations also have different approaches when it comes to which drugs are made legal and which are not. In Germany, drugs such as cocaine, heroin, crystal meth, ecstasy, and cannabis are all illegal. The German government is going through the process of legalizing cannabis. However, this is proving to be a long and complex undertaking. Illegal drug use in Germany Illegal drug use and abuse are prevalent all over the world, and Germany is no different. In 2023, there were over ***** drug-related deaths in Germany. The most common cause of death related to drugs was damage caused by long-term drug use. Other causes included mixes of various drugs causing an overdose. The average age of people who had drug-related deaths in Germany was ** years old, which is almost half the average life expectancy in Germany. This is not surprising, considering the physical toll that prolonged drug use can take on the body, and the risks of accidentally taking drugs that are contaminated or even laced with other even stronger substances when buying on the black market.

Marijuana is by far the most used illicit drug in the United States, with over 64 million people using this drug in 2024. The second most used drug at that time was cocaine, followed by methamphetamine and ecstasy. The United States has had a complicated history with drugs, from fighting a “War on Drugs” starting in the 1970s, to seeing the legalisation of marijuana in many states, and experiencing an ongoing nationwide opioid overdose epidemic. Recreational marijuana Although marijuana is still illegal under federal law, 21 states have legalized the recreational use of marijuana. This legalization has opened a new and thriving market in these states. It is estimated that sales of legal cannabis will reach around 25 billion U.S. dollars by the year 2025. Although support for the legalization of marijuana has not always been strong, now around 68 percent of U.S. adults believe it should be made legal. The opioid epidemic The opioid epidemic describes a rise in overdose deaths in the U.S. due to prescription opioids, heroin, and illegally manufactured synthetic opioids such as fentanyl. The epidemic stems from misleading information from pharmaceutical companies concerning the dangers of opioids such as oxycontin, overprescribing of opioids from physicians, and an influx of easily accessible heroin and highly potent synthetic opioids. In 2022, there were around 81,806 deaths from opioid overdose in the United States.

In 2021/2022, the states with the highest share of people who had used cocaine in the past year were Colorado, Vermont, the District of Columbia, Rhode Island and Massachusetts. In Colorado, around 3.06 percent of the population were estimated to have used cocaine in the past year at that time, compared to the U.S. average of 1.95 percent. The states with the lowest past-year cocaine consumption rates were New Hampshire and Wyoming. Cocaine use in the United States As of 2022, cocaine was the second most used illicit drug in the United States, behind marijuana. At that time around 42.2 million people in the U.S. had used cocaine at least once in their lifetime. In comparison, around 29.5 million people reported using LSD in their lifetime and 22.1 million had used ecstasy. In 2022, almost 5.2 million people were estimated to have used cocaine in the past year. How many people in the U.S. die from cocaine every year? The number of drug poisoning deaths involving cocaine has increased significantly over the past couple decades. In 2021, there were around 24,486 overdose deaths involving cocaine, compared to just 3,800 in the year 1999. However, it is important to note that many overdose deaths involving cocaine also involve other drugs, namely opioids. The increase in overdose deaths involving cocaine is directly related to the ongoing opioid epidemic in the United States. Rates of overdose death involving cocaine are twice as high for men than women, but death rates for both men and women have increased in recent years.

Cannabis is by far the most used drug across the population of the European Union, with almost 30 percent using at some point during their lifetime. Followed by cocaine, which 5 percent have used in their life, and then MDMA, with 4 percent of individuals having used. Highest users of cannabis Europe Czechia and France had the highest prevalence of cannabis use among adults in Europe in 2020, with 11 percent of their populations consuming cannabis. This was followed by Spain, with 10.5 percent of the population using cannabis. Dangerous side to drugs In 2020, 45 percent of those who died as a result of drug use in Europe were aged between 40 and 64 years, while 39 percent of drug deaths were among 25 to 39-year-olds. Norway was the country in Europe with the highest incidence of drug deaths in 2020 at 85 deaths per million population.

In 2007, the price per gram of opium was variable across different countries. Canada had the highest price per gram of opium at almost ** U.S. dollars per gram. Among countries with lower costs for opium, China had the lowest costs at less than *** U.S. dollars per gram. Opium is a depressant drug derived from the seedpods of the poppy flower.

Opioid usage

Opium is a form of opioid which acts on brain function and slows the body’s responses. It is estimated that Asia has the highest share of all opioid users globally. There are many types of opioids available by prescription including Fentanyl, OxyContin and Vicodin. Fentanyl, a synthetic opioid available by prescription for pain management. Globally, the United States has the highest percentage of fentanyl consumption.

Global drug deaths

Other illicit drugs that are used globally include cannabis, amphetamines, opiates, cocaine and ecstasy. In general, global illegal drug use has been on the rise. The most frequently used illicit drug globally is cannabis, followed by opioids and amphetamines. Illegal use of drugs often leads to serious complications. Opioid use disorders were the second leading cause of deaths attributable to drug use worldwide in 2016.