Comprehensive dataset containing 12 verified Enigma locations in United States with complete contact information, ratings, reviews, and location data.

The BRCA Share [40] repository contains variants from the UMD and the testing labs Quest Diagnostics and Laboratory Corporation of America (LabCorp). The contents of BRCA Share are available to academic researchers free of charge and to commercial partners under a subscription fee. To assess ENIGMA’s concordance with BRCA Share, we analyzed 5,452 variants—most of the BRCA Share set—by running them through the BRCA Exchange pipeline. BRCA Share contained 3,938 variants not assessed by ENIGMA, and BRCA Exchange contained 4,640 variants that were assessed by ENIGMA but not found in BRCA Share. In addition, we considered a consensus classification based on available ClinVar, LOVD, BIC, and ENIGMA classifications. For these consensus classifications, there were 2,228 variants in BRCA Share with no reference assertion in BRCA Exchange and 13,341 with reference assertions in BRCA Exchange but no assessment in BRCA Share. We compared the clinical significance assessments of the BRCA Share variants with the 6,154 assessments from ENIGMA and the 16,565 BRCA Exchange consensus reference interpretations. Overall, the clinical assessments showed a strong similarity. “Most Neutral” or “Likely Neutral” variants in BRCA Share were assessed as “Benign” or “Likely Benign” in BRCA Exchange, and most “Causal” or “Likely Causal” variants in BRCA Share were assessed as “Pathogenic” or “Likely Pathogenic” in BRCA Exchange. The largest differences were in the VUS counts. BRCA Share contained 310 variants designated as VUS that were assessed by ENIGMA—296 as “Benign” or “Likely Benign” and 14 as “Pathogenic.” BRCA Share also contained 473 variants designated VUS that were assessed in BRCA Exchange consensus—431 as “Benign” or “Likely Benign,” and 42 as “Pathogenic” or “Likely Pathogenic” (there are also 1,177 variants listed as VUS in both BRCA Share and BRCA Exchange consensus). In comparison to the number of variant classifications analyzed (5,552 from BRCA Share, 6,154 from ENIGMA, 16,565 from BRCA Exchange), this represents a high rate of concordance, which speaks favorably to the overall quality of the public variation data. Furthermore, the amount of new variant information in BRCA Share, beyond that which is available in BRCA Exchange, illustrates the potential gains of expanding data-sharing efforts. BIC, Breast Cancer Information Core; ENIGMA, Evidence-based Network for the Interpretation of Germline Mutant Alleles; LOVD, Leiden Open Variation Database; UMD, Universal Mutation Database; VUS, variants of uncertain significance. (XLSX)

About this dataset

Context

The dataset tabulates the Enigma population distribution across 18 age groups. It lists the population in each age group along with the percentage population relative of the total population for Enigma. The dataset can be utilized to understand the population distribution of Enigma by age. For example, using this dataset, we can identify the largest age group in Enigma.

Key observations

The largest age group in Enigma, GA was for the group of age 60-64 years with a population of 155 (12.57%), according to the 2021 American Community Survey. At the same time, the smallest age group in Enigma, GA was the 85+ years with a population of 0 (0.00%). Source: U.S. Census Bureau American Community Survey (ACS) 2017-2021 5-Year Estimates.

Content

When available, the data consists of estimates from the U.S. Census Bureau American Community Survey (ACS) 2017-2021 5-Year Estimates.

Age groups:

• Under 5 years
• 5 to 9 years
• 10 to 14 years
• 15 to 19 years
• 20 to 24 years
• 25 to 29 years
• 30 to 34 years
• 35 to 39 years
• 40 to 44 years
• 45 to 49 years
• 50 to 54 years
• 55 to 59 years
• 60 to 64 years
• 65 to 69 years
• 70 to 74 years
• 75 to 79 years
• 80 to 84 years
• 85 years and over

Variables / Data Columns

• Age Group: This column displays the age group in consideration
• Population: The population for the specific age group in the Enigma is shown in this column.
• % of Total Population: This column displays the population of each age group as a proportion of Enigma total population. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for Enigma Population by Age. You can refer the same here

Enigma Events Pty Limited Export Import Data. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.

Comprehensive dataset containing 22 verified Enigma locations in RS with complete contact information, ratings, reviews, and location data.

This dataset contains the predicted prices of the asset Enigma over the next 16 years. This data is calculated initially using a default 5 percent annual growth rate, and after page load, it features a sliding scale component where the user can then further adjust the growth rate to their own positive or negative projections. The maximum positive adjustable growth rate is 100 percent, and the minimum adjustable growth rate is -100 percent.

462 Global export shipment records of Enigma Bowl with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

Protein-Protein, Genetic, and Chemical Interactions for Kales SC (2014):Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A. curated by BioGRID (https://thebiogrid.org); ABSTRACT: The Cbl proteins (Cbl, Cbl-b, and Cbl-c) are a highly conserved family of RING finger ubiquitin ligases (E3s) that function as negative regulators of tyrosine kinases in a wide variety of signal transduction pathways. In this study, we identify a new Cbl-c interacting protein, Enigma (PDLIM7). This interaction is specific to Cbl-c as Enigma fails to bind either of its closely related homologues, Cbl and Cbl-b. The binding between Enigma and Cbl-c is mediated through the LIM domains of Enigma as removal of all three LIM domains abrogates this interaction, while only LIM1 is sufficient for binding. Here we show that Cbl-c binds wild-type and MEN2A isoforms of the receptor tyrosine kinase, RET, and that Cbl-c enhances ubiquitination and degradation of activated RET. Enigma blocks Cbl-c-mediated RETMEN2A ubiquitination and degradation. Cbl-c decreased downstream ERK activation by RETMEN2A and co-expression of Enigma blocked the Cbl-c-mediated decrease in ERK activation. Enigma showed no detectable effect on Cbl-c-mediated ubiquitination of activated EGFR suggesting that this effect is specific to RET. Through mapping studies, we show that Cbl-c and Enigma bind RETMEN2A at different residues. However, binding of Enigma to RETMENA prevents Cbl-c recruitment to RETMEN2A. Consistent with these biochemical data, exploratory analyses of breast cancer patients with high expression of RET suggest that high expression of Cbl-c correlates with a good outcome, and high expression of Enigma correlates with a poor outcome. Together, these data demonstrate that Cbl-c can ubiquitinate and downregulate RETMEN2A and implicate Enigma as a positive regulator of RETMEN2A through blocking of Cbl-mediated ubiquitination and degradation.

Enigma Events Limited Export Import Data. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.

Enigma Export Import Data. Follow the Eximpedia platform for HS code, importer-exporter records, and customs shipment details.

Comprehensive dataset containing 20 verified Enigma locations in Italy with complete contact information, ratings, reviews, and location data.

Custom Model Enigma

## Overview

Custom Model Enigma is a dataset for object detection tasks - it contains Objects annotations for 448 images.

## Getting Started

You can download this dataset for use within your own projects, or fork it into a workspace on Roboflow to create your own model.

  ## License

  This dataset is available under the [CC BY 4.0 license](https://creativecommons.org/licenses/CC BY 4.0).

An online question and answer platform has hired you as a data scientist to identify the best question authors on the platform. This identification will bring more insight into increasing the user engagement. Given the tag of the question, number of views received, number of answers, username and reputation of the question author, the problem requires you to predict the upvote count that the question will receive.

This dataset provides information about the number of properties, residents, and average property values for Nashville Enigma Road cross streets in Enigma, GA.

Comprehensive dataset containing 80 verified Enigma locations in Russia with complete contact information, ratings, reviews, and location data.

Objective: Our study addressed aims: (1) test the hypothesis that moderate-severe TBI in pediatric patients is associated with widespread white matter (WM) disruption; (2) test the hypothesis that age and sex impact WM organization after injury; and (3) examine associations between WM organization and neurobehavioral outcomes.

Methods: Data from ten previously enrolled, existing cohorts recruited from local hospitals and clinics were shared with the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Pediatric msTBI working group. We conducted a coordinated analysis of diffusion MRI (dMRI) data using the ENIGMA dMRI processing pipeline.

Results: Five hundred and seven children and adolescents (244 with complicated mild to severe TBI [msTBI] and 263 controls) were included. Patients were clustered into three post-injury intervals: acute/subacute - <2 months, post-acute - 2-6 months, chronic - 6+ months. Outcomes were dMRI metrics and post-injury behavioral problems as...

FBI National Incident-Based Reporting System (FBI NIBRS) crime data for Enigma Police Department (City) in Georgia, including incidents, statistics, demographics, and detailed incident information.

About this dataset

Context

The dataset tabulates the Enigma population distribution across 18 age groups. It lists the population in each age group along with the percentage population relative of the total population for Enigma. The dataset can be utilized to understand the population distribution of Enigma by age. For example, using this dataset, we can identify the largest age group in Enigma.

Key observations

The largest age group in Enigma, GA was for the group of age 45 to 49 years years with a population of 167 (11.74%), according to the ACS 2019-2023 5-Year Estimates. At the same time, the smallest age group in Enigma, GA was the 70 to 74 years years with a population of 9 (0.63%). Source: U.S. Census Bureau American Community Survey (ACS) 2019-2023 5-Year Estimates

Content

When available, the data consists of estimates from the U.S. Census Bureau American Community Survey (ACS) 2019-2023 5-Year Estimates

Age groups:

• Under 5 years
• 5 to 9 years
• 10 to 14 years
• 15 to 19 years
• 20 to 24 years
• 25 to 29 years
• 30 to 34 years
• 35 to 39 years
• 40 to 44 years
• 45 to 49 years
• 50 to 54 years
• 55 to 59 years
• 60 to 64 years
• 65 to 69 years
• 70 to 74 years
• 75 to 79 years
• 80 to 84 years
• 85 years and over

Variables / Data Columns

• Age Group: This column displays the age group in consideration
• Population: The population for the specific age group in the Enigma is shown in this column.
• % of Total Population: This column displays the population of each age group as a proportion of Enigma total population. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for Enigma Population by Age. You can refer the same here

This dataset contains the predicted prices of the asset Enigma’s first Zora over the next 16 years. This data is calculated initially using a default 5 percent annual growth rate, and after page load, it features a sliding scale component where the user can then further adjust the growth rate to their own positive or negative projections. The maximum positive adjustable growth rate is 100 percent, and the minimum adjustable growth rate is -100 percent.

This dataset provides information about the number of properties, residents, and average property values for Enigma Turner Church Road cross streets in Enigma, GA.