analyze the current population survey (cps) annual social and economic supplement (asec) with r the annual march cps-asec has been supplying the statistics for the census bureau's report on income, poverty, and health insurance coverage since 1948. wow. the us census bureau and the bureau of labor statistics ( bls) tag-team on this one. until the american community survey (acs) hit the scene in the early aughts (2000s), the current population survey had the largest sample size of all the annual general demographic data sets outside of the decennial census - about two hundred thousand respondents. this provides enough sample to conduct state- and a few large metro area-level analyses. your sample size will vanish if you start investigating subgroups b y state - consider pooling multiple years. county-level is a no-no. despite the american community survey's larger size, the cps-asec contains many more variables related to employment, sources of income, and insurance - and can be trended back to harry truman's presidency. aside from questions specifically asked about an annual experience (like income), many of the questions in this march data set should be t reated as point-in-time statistics. cps-asec generalizes to the united states non-institutional, non-active duty military population. the national bureau of economic research (nber) provides sas, spss, and stata importation scripts to create a rectangular file (rectangular data means only person-level records; household- and family-level information gets attached to each person). to import these files into r, the parse.SAScii function uses nber's sas code to determine how to import the fixed-width file, then RSQLite to put everything into a schnazzy database. you can try reading through the nber march 2012 sas importation code yourself, but it's a bit of a proc freak show. this new github repository contains three scripts: 2005-2012 asec - download all microdata.R down load the fixed-width file containing household, family, and person records import by separating this file into three tables, then merge 'em together at the person-level download the fixed-width file containing the person-level replicate weights merge the rectangular person-level file with the replicate weights, then store it in a sql database create a new variable - one - in the data table 2012 asec - analysis examples.R connect to the sql database created by the 'download all microdata' progr am create the complex sample survey object, using the replicate weights perform a boatload of analysis examples replicate census estimates - 2011.R connect to the sql database created by the 'download all microdata' program create the complex sample survey object, using the replicate weights match the sas output shown in the png file below 2011 asec replicate weight sas output.png statistic and standard error generated from the replicate-weighted example sas script contained in this census-provided person replicate weights usage instructions document. click here to view these three scripts for more detail about the current population survey - annual social and economic supplement (cps-asec), visit: the census bureau's current population survey page the bureau of labor statistics' current population survey page the current population survey's wikipedia article notes: interviews are conducted in march about experiences during the previous year. the file labeled 2012 includes information (income, work experience, health insurance) pertaining to 2011. when you use the current populat ion survey to talk about america, subract a year from the data file name. as of the 2010 file (the interview focusing on america during 2009), the cps-asec contains exciting new medical out-of-pocket spending variables most useful for supplemental (medical spending-adjusted) poverty research. confidential to sas, spss, stata, sudaan users: why are you still rubbing two sticks together after we've invented the butane lighter? time to transition to r. :D

ORIGINAL DATA SET FOR STUDY OF PUBLICATION AND CITATION TRENDS, TROPICAL MEDICINE, EARLY COVID 19 PANDEMIC. Background: An adequate response to health needs includes the identification of research patterns about the large number of people living in the tropics and subjected to tropical diseases. Studies have shown that research does not always match the real needs of those populations, and that citation reflects mostly the amount of money behind particular publications. Here we test the hypothesis that research from richer institutions is published in better-indexed journals, and thus has greater citation rates. Methods: The data in this study was extracted from the Science Citation Index Expanded database; the 2020 journal Impact Factor (IF2020) was updated to 30 June 2021. We considered places, subjects, institutions and journals. Results: We identified 1 041 highly cited articles with 100 citations or more in the category of tropical medicine. About a decade is needed for an article to reach peak citation. Only two Covid-19 related were highly cited in the last three years. Most cited articles were published by the journals Memorias Do Instituto Oswaldo Cruz (Brazil), Acta Tropica (Switzerland), and PLoS Neglected Tropical Diseases (USA). The USA dominated five of the six publication indicators. International collaboration articles had more citations than single-country articles. The UK, South Africa, and Switzerland had high citation rates, as did the London School of Hygiene and Tropical Medicine in the UK, the Centers for Disease Control and Prevention in the USA, and the WHO in Switzerland. Conclusions: About ten years of accumulated citations are needed to get 100 citations or more as highly cited articles in the Web of Science category of tropical medicine. Six publication and citation indicators, including authors’ publication potential and characteristics evaluated by Y-index, indicate that the currently available indexing system places tropical researchers at a disadvantage against their colleagues in temperate countries, and suggest that, to progress towards better control of tropical diseases, international collaboration should increase, and other tropical countries should follow the example of Brazil, which provides significant financing to its scientific community.Julián Monge-Nájera1, and Yuh-Shan Ho2* 1Laboratorio de Ecología Urbana, Vicerrectoría de Investigación, Universidad Estatal a Distancia, 2050 San José, Costa Rica; julianmonge@gmail.com (https://orcid.org/0000-0001-7764-2966) *Corresponding author: Trend Research Centre, Asia University, No. 500 Lioufeng Road, Wufeng, Taichung 41354, Taiwan; ysho@asia.edu.tw (https://orcid.org/0000-0002-2557-8736) {"references": ["Monge-Najera and Ho. (2023). Highly cited tropical medicine articles in the Web of Science from 1991 to 2020: A bibliometric analysis"]} Full data set in Excel, most cited tropical medicine articles at the beginning of the COVID 19 pandemic

Racial disparities arise across many vital areas of American life, including employment, health, and interpersonal treatment. For example, 1 in 3 Black children live in poverty (vs. 1 in 9 White children) and on average, Black Americans live 4 fewer years than White Americans. Which disparity is more likely to spark reduction efforts? We find that highlighting disparities in health-related (vs. economic) outcomes spurs greater social media engagement and support for disparity-mitigating policy. Further, reading about racial health disparities elicits greater support for action (e.g., protesting) than economic or belonging-based disparities. This occurs, in part, because people view health disparities as violating morally-sacred values which enhances perceived injustice. This work elucidates which manifestations of racial inequality are most likely to prompt Americans to action., The data from Studies 1a, 1b, 3, 4a, and 4b were collected via online platfroms (i.e., Mturk.com, Prolific Academic, and NORC’s AmeriSpeak Panel). All analyses were run in R with the R code provided (title: Health_Disparities_Syntax.R)., , # Highlighting Health Consequences of Racial Disparities Sparks Support for Action

There are a total of 5 datasets available (Studies 1a, 1b, 3, 4a, 4b) each collected by the researchers from online survey platforms. All data files are .sav files. We recommed using SPSS or RStudio to work with the data. We provide our code using RStudio and a codebook with the name of all variables in each dataset.

Description of the data and file structure

Study 1a and Study 1b utilized a within-subjects experimental design (S1a: N=191; S1b, preregistered: N=337, 50% White participants, 50% Black participants) where samples of U.S. citizens recruited from MTurk.com and Prolific Academic read nine examples of racial disparities, three each from the domains of health, economics, and belonging. After each example, participants reported whether the disparity was unjust and fair (reverse-coded; 2-items averaged to create a perceived injustice scale). Participants also indicated their agreement (1=s...

Abstract

Young Lives: An International Study of Childhood Poverty is a collaborative project investigating the changing nature of childhood poverty in selected developing countries. The UK’s Department for International Development (DFID) is funding the first three-year phase of the project.

Young Lives involves collaboration between Non Governmental Organisations (NGOs) and the academic sector. In the UK, the project is being run by Save the Children-UK together with an academic consortium that comprises the University of Reading, London School of Hygiene and Tropical Medicine, South Bank University, the Institute of Development Studies at Sussex University and the South African Medical Research Council.

The study is being conducted in Ethiopia, India (in Andhra Pradesh), Peru and Vietnam. These countries were selected because they reflect a range of cultural, geographical and social contexts and experience differing issues facing the developing world; high debt burden, emergence from conflict, and vulnerability to environmental conditions such as drought and flood.

Objectives of the study The Young Lives study has three broad objectives: • producing good quality panel data about the changing nature of the lives of children in poverty. • trace linkages between key policy changes and child poverty • informing and responding to the needs of policy makers, planners and other stakeholders There will also be a strong education and media element, both in the countries where the project takes place, and in the UK.

The study takes a broad approach to child poverty, exploring not only household economic indicators such as assets and wealth, but also child centred poverty measures such as the child’s physical and mental health, growth, development and education. These child centred measures are age specific so the information collected by the study will change as the children get older.

Further information about the survey, including publications, can be downloaded from the Young Lives website.

Geographic coverage

Young Lives is an international study of childhood poverty, involving 12,000 children in 4 countries. - Ethiopia (20 communities in Addis Ababa, Amhara, Oromia, and Southern National, Nationalities and People's Regions) - India (20 sites across Andhra Pradesh and Telangana) - Peru (74 communities across Peru) - Vietnam (20 communities in the communes of Lao Cai in the north-west, Hung Yen province in the Red River Delta, the city of Danang on the coast, Phu Yen province from the South Central Coast and Ben Tre province on the Mekong River Delta)

Analysis unit

Individuals; Families/households

Universe

Location of Units of Observation: Cross-national; Subnational Population: Children aged approximately 1 year old and their households, and children aged 8 years old and their households, in Ethiopia, India (Andhra Pradesh), Peru and Vietnam, in 2002. See documentation for details of the exact regions covered in each country.

Kind of data

Sample survey data [ssd]

Sampling procedure

Purposive selection/case studies

A key need for the study's objectives was to obtain data at different levels - the children, their households, the community in which they resided, as well as at regional and national levels. This need thus determined that children should be selected in geographic clusters rather than randomly selected across the country. There was, however, a much more important reason for recruiting children in clusters - the sites are also intended to provide suitable settings for a range of complementary thematic studies. For example, one or a few sites may be used for a qualitative study designed to achieve a deeper level of understanding of some social issues, either because they are important in that particular place, or because the sites are appropriate locales to investigate a more general concern. The quantitative panel study is seen as the foundation upon which a coherent and interesting range of linked studies can be set up.

Thus the design was decided, in each country, comprising 20 geographic clusters with 100 children sampled in each cluster.

For details on sample design, see the methodological document which is available in the documentation.

Sampling deviation

Ethiopia: 1,999 (1-year-olds), 1,000 (8-year-olds); India: 2,011 (1-year-olds), 1,008 (8-year-olds); Peru: 2,052 (1-year-olds), 714 (8-year-olds); Vietnam: 2,000 (1-year-olds), 1,000 (8-year-olds).

Mode of data collection

Face-to-face interview

Research instrument

Every questionnaire used in the study consists of a 'core' element and a country-specific element, which focuses on issues important for that country.

The core element of the questionnaires consists of the following sections: Core 6-17.9 month old household questionnaire • Section 1: Locating information • Section 2: Household composition • Section 3: Pregnancy, delivery and breastfeeding • Section 4: Child care • Section 5: Child health • Section 6: Caregiver background • Section 7: Livelihoods and time allocation • Section 8: Economic changes • Section 9: Socio-economic status • Section 10: Caregiver psychosocial well-being • Section 11: Social capital • Section 12: Tracking details • Section 13: Anthropometry

Core 7.5-8.5 year old household questionnaire • Section 1: Locating information • Section 2: Household composition • Section 3: Births and deaths • Section 4: Child school • Section 5: Child health • Section 6: Caregiver background • Section 7: Livelihoods and time allocation • Section 8: Economic changes • Section 9: Socio-economic status • Section 10: Child mental health • Section 11: Social capital • Section 12: Tracking details • Section 13: Anthropometry

The communnity questionnaire consists of the following sections: • Section 1: Physical environment • Section 2: Social environment • Section 3: Infrastructure and access • Section 4: Economy • Section 5: Health and education

Changelog:

Update September 20, 2021: Data and overview updated to reflect data used in the September 15 story Over Half of States Have Rolled Back Public Health Powers in Pandemic. It includes 303 state or local public health leaders who resigned, retired or were fired between April 1, 2020 and Sept. 12, 2021. Previous versions of this dataset reflected data used in the Dec. 2020 and April 2021 stories.

Overview

Across the U.S., state and local public health officials have found themselves at the center of a political storm as they combat the worst pandemic in a century. Amid a fractured federal response, the usually invisible army of workers charged with preventing the spread of infectious disease has become a public punching bag.

In the midst of the coronavirus pandemic, at least 303 state or local public health leaders in 41 states have resigned, retired or been fired since April 1, 2020, according to an ongoing investigation by The Associated Press and KHN.

According to experts, that is the largest exodus of public health leaders in American history.

Many left due to political blowback or pandemic pressure, as they became the target of groups that have coalesced around a common goal — fighting and even threatening officials over mask orders and well-established public health activities like quarantines and contact tracing. Some left to take higher profile positions, or due to health concerns. Others were fired for poor performance. Dozens retired. An untold number of lower level staffers have also left.

The result is a further erosion of the nation’s already fragile public health infrastructure, which KHN and the AP documented beginning in 2020 in the Underfunded and Under Threat project.

Findings

The AP and KHN found that:

• One in five Americans live in a community that has lost its local public health department leader during the pandemic
• Top public health officials in 28 states have left state-level departments ## Using this data To filter for data specific to your state, use this query

To get total numbers of exits by state, broken down by state and local departments, use this query

Methodology

KHN and AP counted how many state and local public health leaders have left their jobs between April 1, 2020 and Sept. 12, 2021.

The government tasks public health workers with improving the health of the general population, through their work to encourage healthy living and prevent infectious disease. To that end, public health officials do everything from inspecting water and food safety to testing the nation’s babies for metabolic diseases and contact tracing cases of syphilis.

Many parts of the country have a health officer and a health director/administrator by statute. The analysis counted both of those positions if they existed. For state-level departments, the count tracks people in the top and second-highest-ranking job.

The analysis includes exits of top department officials regardless of reason, because no matter the reason, each left a vacancy at the top of a health agency during the pandemic. Reasons for departures include political pressure, health concerns and poor performance. Others left to take higher profile positions or to retire. Some departments had multiple top officials exit over the course of the pandemic; each is included in the analysis.

Reporters compiled the exit list by reaching out to public health associations and experts in every state and interviewing hundreds of public health employees. They also received information from the National Association of City and County Health Officials, and combed news reports and records.

Public health departments can be found at multiple levels of government. Each state has a department that handles these tasks, but most states also have local departments that either operate under local or state control. The population served by each local health department is calculated using the U.S. Census Bureau 2019 Population Estimates based on each department’s jurisdiction.

KHN and the AP have worked since the spring on a series of stories documenting the funding, staffing and problems around public health. A previous data distribution detailed a decade's worth of cuts to state and local spending and staffing on public health. That data can be found here.

Attribution

Findings and the data should be cited as: "According to a KHN and Associated Press report."

Is Data Missing?

If you know of a public health official in your state or area who has left that position between April 1, 2020 and Sept. 12, 2021 and isn't currently in our dataset, please contact authors Anna Maria Barry-Jester annab@kff.org, Hannah Recht hrecht@kff.org, Michelle Smith mrsmith@ap.org and Lauren Weber laurenw@kff.org.

Abstract

The Integrated Household Income and Expenditure Survey with Living Standards Measurement Survey 2002-2003 is one of the biggest national surveys carried out in accordance with an international methodology with technical and financial support from the World Bank and United Nations Development Programme.

Background This survey was developed in response to provide the picture of the current situation of poverty in Mongolia in relation to social and economic indicators and contribute toward implementation and progress on National Millennium Development Goals articulated in the National Millennium Development Report and monitoring of the Economic Growth Support and Poverty Reduction Strategy, as well as toward developing and designing future policies and actions. Also, the survey enriched the national database on poverty and contributed in improving the professional capacity of experts and professionals of the National Statistical Office of Mongolia.

Purpose Since the onset of the transition to a market economy of Mongolia our country the need to study changes in people's living standards in relation to household members' demographic situation, their education, health, employment and household engagement in private enterprises has become extremely important. With that purpose and with the support of the World Bank and the United Nations Development Programme, the National Statistical Office of Mongolia conducted the Integrated Household Income and Expenditure Survey with Living Standards Measurement Survey-like features between 2002 and 2003. In conjunction with LSMS household interviews the NSO also collected a price and a community questionnaire in each selected soum. The latter collected information on the quality of infrastructure, and basic education and health services.

Main importance of the survey is to provide policy makers and decision makers with realistic information about poverty and will become a resource for experts and researchers who are interested in studying poverty as well as social and economic issues of Mongolia.

In July 2003 the Government of Mongolia completed the Economic Growth and Poverty Reduction Strategy Paper in which the Government gave high priority to the fight against poverty. As part of that commitment this paper is a study that intends to monitor poverty and understand its main causes in order to provide policy-makers with useful information to improve pro-poor policies.

Content The Integrated HIES with LSMS design has the peculiarity of being a sub-sample of a larger survey, namely the Household Income and Expenditure Survey 2002. Instead of administering an independent consumption module, the Integrated HIES with LSMS 2002-2003 depends on the HIES 2002 information on household consumption expenditure. This is why the survey is referred as Integrated HIES with LSMS 2002-2003. This survey is the only source of information of income-poverty, and the questionnaire is designed to provide poverty estimates and a set of useful social indicators that can monitor more in general human development, as well as more specific issues on key sectors, such as health, education, and energy. And, the price and social survey, in conjunction with LSMS household interviews, collected information on the quality of infrastructure, and basic education and health services of each selected soum.

HIES - food expenditure and consumption, non-food expenditure, other expense, income LSMS - general information, household roster, housing, education, employment, health, fertility, migration, agriculture, livestock, non-farm enterprises, other souces of income, savings and loans, remittances, durable goods, energy PRICE SURVEY - prices of household consumer goods and services SOCIAL SURVEY - population and households, economy and infrastructure, education, health, agriculture and livestock, and non-agricultural business

Survey results The final report of this survey has main results on key poverty indicators, used internationally, as they relate to various social sectors. Its annexes contain information regarding the consumption structure, poverty lines along with the methodology used, as well as some statistical indicators.

The main contributions of this survey report are: - new poverty estimates based on the latest available household survey, the Integrated HIES with LSMS 2002-2003 - the implementation of appropriate, and internationally accepted, methodologies in the calculation of poverty and its analysis (these methodologies may constitute a reference for the analysis of future surveys) - a 'poverty profile' that describes the main characteristics of poverty

The first section of the report provides information on the Mongolian economic background, and presents the basic poverty measures that are linked to the economic performance to offer an indication of what happened to poverty and inequality in recent years. A second section goes in much more detail in generating and describing the poverty profile, in particular looking at the geographical distribution of poverty, poverty and its correlation with household demographic characteristics, characteristics of the household head, employment, and assets. A final section looks at poverty and social sectors and investigates various aspects of education, health and safety nets. The report contains also a number of useful, but more technical appendixes with information about the HIES-LSMS 2002-2003 (sample design and data quality), on the methodology used to construct the basic welfare indicator, and set the poverty line, some sensitivity analysis, and additional statistical information.

Geographic coverage

The survey is nationally representative and covers the whole of Mongolia.

Analysis unit

• Household (defined as a group of persons who usually live and eat together)
• Household member (defined as members of the household who usually live in the household, which may include people who did not sleep in the household the previous night, but does not include visitors who slept in the household the previous night but do not usually live in the household)
• Selected soums (for collecting prices of household consumer goods and services and information on quality of infrastructure, basic education, health services and so on)

Universe

The survey covered selected households and all members of the households (usual residents). And the price and social surveys covered all selected soums.

Kind of data

Sample survey data [ssd]

Sampling procedure

The Integrated HIES with LSMS 2002-2003 households are a subset of the household interviewed for the HIES 2002. One third of the HIES 2002 households were contacted again and interviewed on the LSMS topics. The subset was equally distributed among the four quarters.

The HIES 2002, and consequently the Integrated HIES with LSMS 2002-2003, used the 2000 Census as sample frame. 1,248 enumerations areas were part of the sample, which is a two-stage stratified random sample. The strata, or domains of estimation, are four: Ulaanbaatar, Aimag capitals and small towns, Soum centres, and Countryside. At a first stage a number of Primary Sampling Units (PSUs) were selected from each stratum. In the selected PSUs enumerators listed all the households residing in the area, and in a second stage households were randomly selected from the list of households identified in that PSU (10 households were selected in urban areas and 8 households in rural areas).

It should be noted that non-response case of households once selected for the survey exerts unfavorable influence on the representativeness of the survey. Therefore an enumerator should take every step to avoid that. To obtain true and timely survey results a proper agreement should be reached with a selected household before a survey starts. One of the main reasons of non-response is that an enumerator doesn't meet with the household members who are able to give the required information. An enumerator should visit a household at least 3 times within the given period to take the questionnaire.

Another common reason is that a household refuses to participate in the survey. In this case an enumerator should explain the purpose of the survey again, explain that the private data will be kept strictly confidential according to the corresponding law. If necessary an enumerator can ask local statistical division or local administration for the help. However this practice is very seldom.

If there is no possibility to take the questionnaires from the selected households due to weather conditions or disasters, reserved households with numbers 11, 12, 13 respectively from the list provided by the NSO should replace the omitted ones. However the reasons of replacements are to be declared in detail on the form.

Sampling deviation

At the planning stage the time lag between the HIES and LSMS interviews was expected to be relatively short. However, for various reasons it is on average of about 9 months, and for some households more than one year. Households interviewed in the first and second quarter of 2002 were generally re-interviewed in March and April 2003, while households of the third and fourth quarter of 2002 were re-interviewed in May, June and July of 2003. The considerable time lag between HIES and LSMS interviews was the main responsible for a considerable loss of households in the LSMS sample, households that could not be easily relocated and therefore re-interviewed. Due also to some incomplete questionnaires, the number of households that were used for the final poverty analysis is 3,308.

Mode of data collection

Face-to-face [f2f]

Research instrument

A

Abstract

Purpose: The multi-country Study on Global Ageing and Adult Health (SAGE) is run by the World Health Organization's Multi-Country Studies unit in the Innovation, Information, Evidence and Research Cluster. SAGE is part of the unit's Longitudinal Study Programme which is compiling longitudinal data on the health and well-being of adult populations, and the ageing process, through primary data collection and secondary data analysis. INDEPTH SAGE Wave 1 (2006/7) provides data on the health and well-being of adults in: Ghana, India and South Africa.

Objectives: To obtain reliable, valid and comparable health, health-related and well-being data over a range of key domains for adult and older adult populations in nationally representative samples To examine patterns and dynamics of age-related changes in health and well-being using longitudinal follow-up of a cohort as they age, and to investigate socio-economic consequences of these health changes To supplement and cross-validate self-reported measures of health and the anchoring vignette approach to improving comparability of self-reported measures, through measured performance tests for selected health domains To collect health examination and biomarker data that improves reliability of morbidity and risk factor data and to objectively monitor the effect of interventions

Additional Objectives: To generate large cohorts of older adult populations and comparison cohorts of younger populations for following-up intermediate outcomes, monitoring trends, examining transitions and life events, and addressing relationships between determinants and health, well-being and health-related outcomes To develop a mechanism to link survey data to demographic surveillance site data To build linkages with other national and multi-country ageing studies To improve the methodologies to enhance the reliability and validity of health outcomes and determinants data To provide a public-access information base to engage all stakeholders, including national policy makers and health systems planners, in planning and decision-making processes about the health and well-being of older adults

Methods: INDEPTH SAGE's first full round of data collection included persons aged 50 years and older in the health and demographic surveillance sites. All persons aged 50+ years (for example, spouses and siblings) were invited to participate. Standardized SAGE survey instruments were used in all countries consisting of two main parts: 1) household questionnaire; 2) individual questionnaire. The procedures for including country-specific adaptations to the standardized questionnaire and translations into local languages from English follow those developed by and used for the World Health Survey.

Content - Household questionnaire 0000 Coversheet 0100 Sampling Information 0200 Geocoding and GPS Information 0300 Recontact Information 0350 Contact Record 0400 Household Roster 0450 Kish Tables and Household Consent 0500 Housing 0600 Household and Family Support Networks and Transfers 0700 Assets and Household Income 0800 Household Expenditures 0900 Interviewer Observations

• Individual questionnaire 1000 Socio-Demographic Characteristics 1500 Work History and Benefits 2000 Health State Descriptions and Vignettes 2500 Anthropometrics, Performance Tests and Biomarkers 3000 Risk Factors and Preventive Health Behaviours 4000 Chronic Conditions and Health Services Coverage 5000 Health Care Utilization 6000 Social Cohesion 7000 Subjective Well-Being and Quality of Life (WHOQoL-8 and Day Reconstruction Method) 8000 Impact of Caregiving 9000 Interviewer Assessment

Geographic coverage

Rural subdistrict Mpumalanga Province

Analysis unit

household and individuals

Universe

Agincourt Health and Demographic Surveillance Site fifty plus population

Kind of data

Sample survey data [ssd]

Sampling procedure

Simple random sample of 575 persons 50 years and older with an oversample of women from the 2005 HDSS census.

Mode of data collection

Face-to-face [f2f]

Research instrument

The questionnaires were based on the WHS Model Questionnaire with some modification and many new additions. A household questionnaire was administered to all households eligible for the study. An Individual questionnaire was administered to eligible respondents identified from the household roster. The questionnaires were developed in English and were piloted as part of the SAGE pretest. All documents were translated into Shangaan.

Cleaning operations

Data editing took place at a number of stages including: (1) office editing and coding (2) during data entry (3) structural checking of the CSPro files (4) range and consistency secondary edits in Stata

Response rate

86% of participants accepted to participate, 10% were not found and 4% refused to participate.

This dataset comprises data extracted from 86 publications included in an umbrella review which compared the effect of colour-associated bioactive pigments found in fruit and vegetables (carotenoids, flavonoids, betalains and chlorophyll) on human health outcomes relevant to public health. Meta-analysed data from 83 systematic literature reviews were available for 17 different bioactive pigments spanning all colours of fruit and vegetables except green, with additional data from two randomised controlled trials and one cohort study for chlorophyll. This dataset represents 2,847 original research studies and data from over 37 million participants. There were 449 meta-analysed health outcomes extracted from the 83 systematic literature reviews. Extracted health outcomes were categorised according to pigment, comparator type, broad health outcome, study design, age group, source of pigment, risk of bias, and confidence in the estimated effect. Data extracted were dose, intervention duration, sample size, number of original studies, effect estimate, 95% confidence intervals, I2 statistics, publication bias and p-value. Rigorous analysis, including estimations of a common effect size, stratification of the evidence, study level sensitivity analyses and reporting on heterogeneity and potential biases, may be carried out using these data, to further evaluate the effect of colour-associated bioactive pigments in fruit and vegetables on human health. Methods A systematic search strategy was implemented across four electronic databases on the 29th October 2021 [1]. The search aimed to identify systematic literature reviews of randomised controlled trials or cohort studies with meta-analyses which compared the effect of colour-associated bioactive pigments found in fruit and vegetables, compared to placebo or low intakes, on human health outcomes relevant to population health. Studies were required to report: (i) colour pigments consumed by humans through whole fruit or vegetables, extract or supplements derived from fruit or vegetables, and (ii) health-related outcomes relevant to population health including the prevention of disease and optimisation of disease risk factors, general wellbeing, function (cognitive function, physical function and exercise performance), growth and development in children, maternal and neonatal health. All identified records were screened for eligibility by two independent researchers. Studies which were considered eligible underwent data extraction by one researcher and checked for accuracy twice by a second investigator. Study, participant and outcome data were extracted, including bioactive pigment name/colour, intervention and comparator conditions (type, duration and dose), number of meta-analysed studies/intervention groups, model, meta-analysed outcome, sample size (intervention/case, comparator/control, and total), effect size and statistical significance, risk of bias, heterogeneity, publication bias and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) quality rating (if reported) [2]. During data extraction, included studies were assessed for methodological quality using the Oxford University, Centre for Evidence-Based Medicine (CEBM) critical appraisal tool for systematic reviews, RCTs or prognostic studies [3]. Meta-analysed data from 83 systematic literature reviews was available for 17 different bioactive pigments spanning all colours of fruit and vegetables except green (i.e., chlorophyll), with additional data from two single randomised controlled trials and one cohort study available for chlorophyll. No data were found for betalains or its sub-classes; however, the betalains colours of red, violet, orange and yellow are represented by the included carotenoids and flavonoids. The 83 included systematic literature reviews measured and reported on 449 eligible meta-analysed health outcomes. Extracted health outcomes were grouped as cancer (reported by 192 meta-analyses), cardiovascular disease (135 meta-analyses), exercise (28 meta-analyses), mortality (27 meta-analyses), type 2 diabetes (24 meta-analyses), obesity (13 meta-analyses), bone health (9 meta-analyses), eye health (9 meta-analyses), the nervous system (5 meta-analyses), pregnancy health (4 meta-analyses), cognitive function (2 meta-analyses) and the respiratory system (1 meta-analysis). Each single randomised controlled trial and cohort study for chlorophyll examined a unique health outcome: cancer (1 cohort study), cardiovascular disease (1 randomised controlled trial) and allergy (1 randomised controlled trial).

Abstract

The surveys is designed to collect, analyze and disseminate demographic and health data pertaining to the Palestinian population living in the Palestinian Territory, with a focus on demography, fertility, family planning and maternal and child health. The 2000 survey also includes new sections and elements, such as basic health and socio-economic information on different groups within the population, and children less than five years, children aged 5-17 years.

Geographic coverage

The Data are representative at region level (West Bank, Gaza Strip), locality type (urban, rural, camp)

Analysis unit

Household, individual

Universe

The survey covered all the Palestinian households who are a usual residence in the Palestinian Territory.

Kind of data

Sample survey data [ssd]

Sampling procedure

Sample frame and sample design: The list of all Palestinian households has been constructed from the updated frame in 1997. The master sample was drawn to be used for different surveys.

The sample type was a stratified cluster random sample: First stage: 481 EAs were selected from all Palestinian Territory. Second stage: A systematic random sample of 120 households was selected from each enumeration Area (EA) in the West Bank and Gaza Strip.

Sample size: The number of the households in the sample was 6,349 households: 4,295 in the West Bank and 2,054 in Gaza Strip.

Moreover, the standard errors of survey estimates must be calculated so that the user may identify the accuracy of the estimates and reliability of the survey. The total error of the survey can be categorized into two types: Statistical errors and non-statistical errors. Non-statistical errors are related to the procedures of statistical operation at the different stages such as failure to interpret the questions of the questionnaire, not wanting or failure to give the correct answer, and poor statistical coverage, etc. These errors depend on the type of work, training and supervision, efficiency of design, implementation and related activities. The work team made best efforts to reduce non-statistical errors during all stages. Statistical errors, however, can be assessed and often measured by the standard deviation, which was calculated using CENVAR software package using the Ultimate Cluster method to calculate variation

Mode of data collection

Face-to-face [f2f]

Research instrument

The questionnaire was consisted of the following parts:

• Household part: consisted household roster including demographic variables such as age, sex, date of birth, smoking, health insurance, labor force status, education variables, and others. In addition to child discipline section for children aged 2-14 years, child labor for children aged 5-17 years and education section for persons aged 5-24 years.
• Dwelling part: including questions on housing conditions such as main drinking water source, iodized salt and other socio-economic indicators.
• Women part: this part was designed to collect data from all ever-married women 15-54 years old. It consists of seven sections: Reproduction, Contraception, Pregnancy and Breast Feeding, Tetanus Toxoid (TT), Health Awareness and Public Health, Awareness of AIDS, Fertility Preference.
• Child part: this part was designed to collect data from all children aged less than 5 years, it consists of five sections: Child Education, Child Labor, Child health and Immunization, Children Ophthalmic Health, and Anthropometry.

Cleaning operations

Data editing took place at a number of stages through the processing including:

1. office editing and coding
2. during data entry
3. structure checking and completeness
4. structural checking of SPSS data files

Response rate

The survey sample consists of about 6,349 cv households of which 6,204 households completed the interview; whereas 4,164 households from the West Bank and 2,040 households in Gaza Strip. Weights were modified to account for non-response rate. The response rate in the West Bank reached 96.9% while in the Gaza Strip it reached 99.3%. The response rate in the Palestinian Territory reached 97.7%.

Sampling error estimates

Detailed information on the sampling Error is available in the Survey Report.

Data appraisal

Detailed information on the data appraisal is available in the Survey Report.

Abstract

The main purpose of a Household Income and Expenditure Survey (HIES) was to present high quality and representative national household data on income and expenditure in order to update Consumer Price Index (CPI), improve statistics on National Accounts and measure poverty within the country.

The main objectives of this survey - update the weight of each expenditure item (from COICOP) and obtain weights for the revision of the Consumer Price Index (CPI) for Funafuti - provide data on the household sectors contribution to the National Accounts - design the structure of consumption for food secutiry - To provide information on the nature and distribution of household income, expenditure and food consumption patterns household living standard useful for planning purposes - To provide information on economic activity of men and women to study gender issues - To generate the income distribution for poverty analysis

The 2010 Household Income and Expenditure Survey (HIES) is the third HIES that was conducted by the Central Statistics Division since Tuvalu gained political independence in 1978.

This survey deals mostly with expenditure and income on the cash side and non cash side (gift, home production). Moreover, a lot of information are collected:

at a household level: - goods possession - description of the dwelling - water tank capacity - fruits and vegetables in the garden - livestock

at an individual level: - education level - employment - health

Geographic coverage

National Coverage: Funafuti and /Outer islands.

Analysis unit

• Household level
• Individual level

Universe

The scope of the 2010 Household Income and Expenditure Survey (HIES) was all occupied households in Tuvalu. Households are the sampling unit, defined as a group of people (related or not) who pool their money, and cook and eat together. It is not the physical structure (dwelling) in which people live. HIES covered all persons who were considered to be usual residents of private dwellings (must have been living in Tuvalu for a period of 12-months, or have intention to live in Tuvalu for a period of 12-months in order to be included in the survey). Usual residents who are temporary away are included as well (e.g., for work or a holiday).

All the private household are included in the sampling frame. In each household selected, the current resident are surveyed, and people who are usual resident but are currently away (work, health, holydays reasons, or border student for example. If the household had been residing in Tuvalu for less than one year: - but intend to reside more than 12 months => he is included - do not intend to reside more than 12 months => out of scope.

Kind of data

Sample survey data [ssd]

Sampling procedure

The Tuvalu 2010 Household Income and Expenditure Survey (HIES) outputs breakdowns at the domain level which is Funafuti and Outer Islands. To achieve this, and to match the budget constraint, a third of the households were selected in both domains. It was decided that 33% (one third) sample was sufficient to achieve suitable levels of accuracy for key estimates in the survey. So the sample selection was spread proportionally across all the islands except Niulakita as it was considered too small. The selection method used is the simple random survey, meaning that within each domain households were directly selected from the population frame (which was the updated 2009 household listing). All islands were included in the selection except Niulakita that was excluded due to its remoteness, and size.

For selection purposes, in the outer island domain, each island was treated as a separate strata and independent samples were selected from each (one third). The strategy used was to list each dwelling on the island by their geographical position and run a systematic skip through the list to achieve the 33% sample. This approach assured that the sample would be spread out across each island as much as possible and thus more representative.

Population and sample counts of dwellings by islands for 2010 HIES Islands: -Nanumea: Population: 123; sample: 41 -Nanumaga: Population: 117; sample: 39 -Niutao: Population: 138; sample: 46 -Nui: Population: 141; sample: 47 -Vaitupu: Population: 298; sample: 100 -Nukufetau: Population: 141; sample: 47 -Nukulaelae: Population: 78; sample: 26 -Funafuti: Population: 791; sample: 254 -TOTAL: Population: 1827; sample: 600.

Mode of data collection

Face-to-face [f2f]

Research instrument

3 forms were used. Each question is writen in English and translated in Tuvaluan on the same version of the questionnaire. The questionnaire was highly based on the previous one (2004 survey).

Household Schedule This questionnaire, to be completed by interviewers, is used to collect information about the household composition, living conditions and is also the main form for collecting expenditure on goods and services purchased infrequently.

• composition of the household and demographic profile of each members
• dwelling information
• dwelling expenditure
• transport expenditure
• education expenditure
• health expenditure
• land and property expenditure
• household furnishing
• home appliances
• cultural and social payments
• holydays/travel costs
• Loans and saving
• clothing
• other major expenditure items

Individual Schedule There will be two individual schedules: - health and education - labor force (individual aged 15 and above) - employment activity and income (individual aged 15 and above): wages and salaries working own business agriculture and livestock fishing income from handicraft income from gambling small scale activies jobs in the last 12 months other income childreen income tobacco and alcohol use other activities seafarer

Diary (one diary per week, on a 2 weeks period, 2 diaries per household were required) The diaries are used to record all household expenditure and consumption over the two week diary keeping period. The diaries are to be filled in by the household members, with the assistance from interviewers when necessary. - All kind of expenses - Home production - food and drink (eaten by the household, given away, sold) - Goods taken from own business (consumed, given away) - Monetary gift (given away, received, winning from gambling) - Non monetary gift (given away, received, winning from gambling).

Cleaning operations

Consistency of the data: - each questionnaire was checked by the supervisor during and after the collection - before data entry, all the questionnaire were coded - the CSPRo data entry system included inconsistency checks which allow the National Statistics Office staff to point some errors and to correct them with imputation estimation from their own knowledge (no time for double entry), 4 data entry operators. 1. presence of all the form for each household 2. consistency of data within the questionnaire

at this stage, all the errors were corrected on the questionnaire and on the data entry system in the meantime.

• after data entry, the extreme amount of each questionnaire where selected in order to check their consistency. at this stage, all the inconsistency were corrected by imputation on CSPRO editing.

Response rate

The final response rates for the survey was very pleasing with an average rate of 97 per cent across all islands selected. The response rates were derived by dividing the number of fully responding households by the number of selected households in scope of the survey which weren't vacant.

Response rates for Tuvalu 2010 Household Income and Expenditure Survey (HIES): - Nanumea 100% - Nanumaga 100% - Niutao 98% - Nui 100% - Vaitupu 99% - Nukufetau 89% - Nukulaelae 100% - Funafuti 96%

As can be seen in the table, four of the islands managed a 100 per cent response, whereas only Nukufetau had a response rate of less than 90 per cent.

Further explanation of response rates can be located in the external resource entitled Tuvalu 2010 HIES Report Table 1.2.

Sampling error estimates

The quality of the results can be found in the report provided in this documentation.

This dataset provides detailed information on various drugs used for a multitude of medical conditions such as acne, cancer, and heart disease. It includes essential details about drug efficacy based on user ratings and experiences, as well as specific information on side effects. The dataset aims to offer insights into how different medications are perceived by users concerning their effectiveness, considering both positive and adverse effects.

Columns

• drug_name: The name of the drug.
• medical_condition: The name of the medical condition the drug is used for. Examples include Pain (defined as "An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage") and Cold Symptoms (also known as Common Cold or Coryza, characterised by congestion of the nasal mucous membrane, watery nasal rhinorrhoea, and general malaise, with a typical duration of 3–5 days).
• medical_condition_description: A detailed description of the medical condition.
• activity: An indicator of recent site visitor activity relative to other medications listed, based on data gathered from drugs.com.
• rx_otc: Indicates the drug's classification:
  • Rx: Prescription Needed.
  • OTC: Over-the-counter, meaning it can be purchased without a medical prescription.
  • Rx/OTC: Can be either prescription or over-the-counter.
• pregnancy_category: Classifies the drug's risk to a foetus during pregnancy:
  • A: Adequate and well-controlled studies show no risk in the first trimester (and no evidence of risk later).
  • B: Animal reproduction studies show no foetal risk, but no adequate human studies exist.
  • C: Animal studies show adverse foetal effects, no adequate human studies, but potential benefits may warrant use despite risks.
  • D: Positive evidence of human foetal risk, but potential benefits may warrant use despite risks.
  • X: Studies show foetal abnormalities and human foetal risk, risks clearly outweigh potential benefits.
  • N: FDA has not classified the drug.
• csa: Controlled Substances Act (CSA) Schedule:
  • M: Multiple schedules, depends on dosage/strength.
  • U: Schedule unknown.
  • N: Not subject to CSA.
  • 1: High abuse potential, no accepted medical use, lack of accepted safety.
  • 2: High abuse potential, accepted medical use (with severe restrictions), abuse may lead to severe dependence.
  • 3: Lower abuse potential than 1 & 2, accepted medical use, abuse may lead to moderate/low physical or high psychological dependence.
  • 4: Low abuse potential relative to 3, accepted medical use, abuse may lead to limited physical or psychological dependence.
  • 5: Low abuse potential relative to 4, accepted medical use, abuse may lead to limited physical or psychological dependence.
• alcohol: Indicates interaction with alcohol (X = Interacts with Alcohol).
• rating: User-assigned rating (1 = not effective, 10 = most effective), reflecting effectiveness, side effects, and ease of use. Ratings range from 0.00 to 10.00.
• no_of_reviews: The number of reviews received for the drug. There are 2912 unique values for this column.

Distribution

The dataset is typically provided in a CSV file format. While specific total row/record counts are not explicitly stated, the presence of 2912 unique review counts and a wide range of ratings suggest a substantial number of entries. The data appears to be structured in a tabular manner.

Usage

This dataset is ideal for: * Analysing drug efficacy based on real-world user feedback. * Researching user experiences with various medications. * Developing applications related to health information systems. * Performing Natural Language Processing (NLP) on drug descriptions and reviews to extract insights. * Understanding the landscape of prescription (Rx) versus over-the-counter (OTC) medications.

Coverage

The dataset's coverage is global, making it relevant for a worldwide audience. It was listed on 11th June 2025. There are no specific notes on demographic scope or data availability for certain groups or years explicitly mentioned.

License

CCO

Who Can Use It

This dataset is suitable for: * Healthcare Professionals: To gain insights into patient experiences and drug effectiveness. * Researchers: For studies on pharmacology, public health, and patient outcomes. * Data Analysts: To identify trends and patterns in drug usage and side effects. * Software Developers: For building health-related applications, AI models, or recommendation systems. * Patients/Consumers: To inform decisions about medications based on aggregated user experiences.

Dataset Name Suggestions

• Drug Efficacy and User Experience Data
• Medication Ratings and Conditions Dataset

Abstract

Purpose: The multi-country Study on Global Ageing and Adult Health (SAGE) is run by the World Health Organization's Multi-Country Studies unit in the Innovation, Information, Evidence and Research Cluster. SAGE is part of the unit's Longitudinal Study Programme which is compiling longitudinal data on the health and well-being of adult populations, and the ageing process, through primary data collection and secondary data analysis. SAGE baseline data (Wave 0, 2002/3) was collected as part of WHO's World Health Survey http://www.who.int/healthinfo/survey/en/index.html (WHS). SAGE Wave 1 (2007/10) provides a comprehensive data set on the health and well-being of adults in six low and middle-income countries: China, Ghana, India, Mexico, Russian Federation and South Africa. Objectives: To obtain reliable, valid and comparable health, health-related and well-being data over a range of key domains for adult and older adult populations in nationally representative samples To examine patterns and dynamics of age-related changes in health and well-being using longitudinal follow-up of a cohort as they age, and to investigate socio-economic consequences of these health changes To supplement and cross-validate self-reported measures of health and the anchoring vignette approach to improving comparability of self-reported measures, through measured performance tests for selected health domains To collect health examination and biomarker data that improves reliability of morbidity and risk factor data and to objectively monitor the effect of interventions

Additional Objectives: To generate large cohorts of older adult populations and comparison cohorts of younger populations for following-up intermediate outcomes, monitoring trends, examining transitions and life events, and addressing relationships between determinants and health, well-being and health-related outcomes To develop a mechanism to link survey data to demographic surveillance site data To build linkages with other national and multi-country ageing studies To improve the methodologies to enhance the reliability and validity of health outcomes and determinants data To provide a public-access information base to engage all stakeholders, including national policy makers and health systems planners, in planning and decision-making processes about the health and well-being of older adults

Methods: SAGE's first full round of data collection included both follow-up and new respondents in most participating countries. The goal of the sampling design was to obtain a nationally representative cohort of persons aged 50 years and older, with a smaller cohort of persons aged 18 to 49 for comparison purposes. In the older households, all persons aged 50+ years (for example, spouses and siblings) were invited to participate. Proxy respondents were identified for respondents who were unable to respond for themselves. Standardized SAGE survey instruments were used in all countries consisting of five main parts: 1) household questionnaire; 2) individual questionnaire; 3) proxy questionnaire; 4) verbal autopsy questionnaire; and, 5) appendices including showcards. A VAQ was completed for deaths in the household over the last 24 months. The procedures for including country-specific adaptations to the standardized questionnaire and translations into local languages from English follow those developed by and used for the World Health Survey.

Content Household questionnaire 0000 Coversheet 0100 Sampling Information 0200 Geocoding and GPS Information 0300 Recontact Information 0350 Contact Record 0400 Household Roster 0450 Kish Tables and Household Consent 0500 Housing 0600 Household and Family Support Networks and Transfers 0700 Assets and Household Income 0800 Household Expenditures 0900 Interviewer Observations

Individual questionnaire 1000 Socio-Demographic Characteristics 1500 Work History and Benefits 2000 Health State Descriptions and Vignettes 2500 Anthropometrics, Performance Tests and Biomarkers 3000 Risk Factors and Preventive Health Behaviours 4000 Chronic Conditions and Health Services Coverage 5000 Health Care Utilization 6000 Social Cohesion 7000 Subjective Well-Being and Quality of Life (WHOQoL-8 and Day Reconstruction Method) 8000 Impact of Caregiving 9000 Interviewer Assessment

Geographic coverage

National coverage

Analysis unit

households and individuals

Universe

The household section of the survey covered all households in 19 of the 28 states in India which covers 96% of the population. Institutionalised populations are excluded. The individual section covered all persons aged 18 years and older residing within individual households.

Kind of data

Sample survey data [ssd]

Sampling procedure

World Health Survey Sampling India has 28 states and seven union territories. 19 of the 28 states were included in the design representing 96% of the population. India used a stratified multistage cluster sample design. Six states were selected in accordance with their geographic location and level of development. Strata were defined by the 6 states:(Assam, Karnataka, Maharashtra, Rajasthan, Uttar Pradesh and West Bengal), and locality (urban or rural). There are 12 strata in total. The 2000 Census demarcation was used as the sampling frame. Two stage and three stage sampling was adopted in rural and urban areas, respectively. In rural areas PSUs(villages) were selected probability proportional to size. The measure of size being the 2001 Census population in the village. SSUs (households) were selected using systematic sampling. TSUs (individuals) were selected using Kish tables. In urban areas, PSUs(city wards) were selected probability proportional to size. SSUs(census enumeration blocks), two were randomly selected from each PSU. TSU (households) were selected using systematic sampling. QSU (individuals) were selected as in rural areas. A sample of 379 EAs was selected as the primary sampling units(PSU).

SAGE Sampling The SAGE sample was pre-determined as all PSUs and households selected for the WHS/SAGE Wave 0 survey were included. Exceptions are three PSUs in Assam which were replaced as they were inaccessible due to flooding. And a further six PSUs were omitted for which the household roster information was not available. In each selected EA, a listing of the households was conducted to classify each household into the following mutually exclusive categories: 1)Households with a WHS/SAGE Wave 0 respondent aged 50-plus: all members aged 50-plus including the WHS/SAGE Wave 0 respondent were eligible for the individual interview. 2)Households with a WHS/SAGE Wave 0 respondent aged 47-49: all members aged 50-plus including the WHS/SAGE Wave 0 respondent aged 47-49 was eligible for the individual interview. 3)Households with a WHS/SAGE Wave 0 female respondent aged 18-46: all females members aged 18-49 including the WHS/SAGE Wave 0 female respondent aged 18-46 were eligible for the individual interview. 4)Households with a WHS/SAGE Wave 0 male respondent aged 18-46: three households were selected using systematic sampling and one male aged 18-49 was eligible for the individual interview. In the households not selected, all members aged 50-plus were eligible for the individual interview.

Stages of selection Strata: State, Locality=12 PSU: EAs=375 surveyed SSU: Households=10424 surveyed TSU: Individual=12198 surveyed

Mode of data collection

Face-to-face [f2f] PAPI

Research instrument

The questionnaires were based on the WHS Model Questionnaire with some modification and many new additions. A household questionnaire was administered to all households eligible for the study. A Verbal Autopsy questionnaire was administered to households that had a death in the last 24 months. An Individual questionniare was administered to eligible respondents identified from the household roster. A Proxy questionnaire was administered to individual respondents who had cognitive limitations. A Womans Questionnaire was administered to all females aged 18-49 years identified from the household roster. The questionnaires were developed in English and were piloted as part of the SAGE pretest in 2005. All documents were translated into Hindi, Assamese, Kanada and Marathi. SAGE generic questionnaires are available as external resources.

Cleaning operations

Data editing took place at a number of stages including: (1) office editing and coding (2) during data entry (3) structural checking of the CSPro files (4) range and consistency secondary edits in Stata

Response rate

Household Response rate=88% Cooperation rate=92%

Individual: Response rate=68% Cooperation rate=92%

Abstract

The multi-country Study on Global Ageing and Adult Health (SAGE) is run by the World Health Organization's Multi-Country Studies unit in the Health Systems and Innovation Cluster. SAGE is part of the unit's Longitudinal Study Programme which is compiling longitudinal data on the health and well-being of adult populations, and the ageing process, through primary data collection and secondary data analysis. SAGE baseline data (Wave 0, 2002/3) was collected as part of WHO's World Health Survey http://www.who.int/healthinfo/survey/en/index.html (WHS). SAGE Wave 2 (2014/15) provides a comprehensive data set on the health and well-being of adults in six low and middle-income countries: China, Ghana, India, Mexico, Russian Federation and South Africa.

Objectives: To obtain reliable, valid and comparable health, health-related and well-being data over a range of key domains for adult and older adult populations in nationally representative samples To examine patterns and dynamics of age-related changes in health and well-being using longitudinal follow-up of a cohort as they age, and to investigate socio-economic consequences of these health changes To supplement and cross-validate self-reported measures of health and the anchoring vignette approach to improving comparability of self-reported measures, through measured performance tests for selected health domains To collect health examination and biomarker data that improves reliability of morbidity and risk factor data and to objectively monitor the effect of interventions

Additional Objectives: To generate large cohorts of older adult populations and comparison cohorts of younger populations for following-up intermediate outcomes, monitoring trends, examining transitions and life events, and addressing relationships between determinants and health, well-being and health-related outcomes To develop a mechanism to link survey data to demographic surveillance site data To build linkages with other national and multi-country ageing studies To improve the methodologies to enhance the reliability and validity of health outcomes and determinants data To provide a public-access information base to engage all stakeholders, including national policy makers and health systems planners, in planning and decision-making processes about the health and well-being of older adults

Methods: SAGE's first full round of data collection included both follow-up and new respondents in most participating countries. The goal of the sampling design was to obtain a nationally representative cohort of persons aged 50 years and older, with a smaller cohort of persons aged 18 to 49 for comparison purposes. In the older households, all persons aged 50+ years (for example, spouses and siblings) were invited to participate. Proxy respondents were identified for respondents who were unable to respond for themselves. Standardized SAGE survey instruments were used in all countries consisting of five main parts: 1) household questionnaire; 2) individual questionnaire; 3) proxy questionnaire; 4) verbal autopsy questionnaire; and, 5) appendices including showcards. A VAQ was completed for deaths in the household over the last 24 months. The procedures for including country-specific adaptations to the standardized questionnaire and translations into local languages from English follow those developed by and used for the World Health Survey.

Content: - Household questionnaire 0000 Coversheet 0100 Sampling Information 0200 Geocoding and GPS Information 0300 Recontact Information 0350 Contact Record 0400 Household Roster 0450 Kish Tables and Household Consent 0500 Housing 0600 Household and Family Support Networks and Transfers 0700 Assets and Household Income 0800 Household Expenditures 0900 Interviewer Observations

• Verbal Autopsy questionnaire Section 1: Information on the Deceased and Date/Place of Death Section 1A7: Vital Registration and Certification Section 2: Information on the Respondent Section 3A: Medical History Associated with Final Illness Section 3B: General Signs and Symptoms Associated with Final Illness Section 3E: History of Injuries/Accidents Section 3G: Health Service Utilization Section 4: Background Section 5A: Interviewer Observations

• Individual questionnaire 1000 Socio-Demographic Characteristics 1500 Work History and Benefits 2000 Health State Descriptions 2500 Anthropometrics, Performance Tests and Biomarkers 3000 Risk Factors and Preventive Health Behaviours 4000 Chronic Conditions and Health Services Coverage 5000 Health Care Utilisation 6000 Social Networks 7000 Subjective Well-Being and Quality of Life (WHOQoL-8 and Day Reconstruction Method) 8000 Impact of Caregiving 9000 Interviewer Assessment

• Proxy Questionnaire Section1 Respondent Characteristics and IQ CODE Section2 Health State Descriptions Section4 Chronic Conditions and Health Services Coverage Section5 Health Care Utilisation

Geographic coverage

National coverage

Analysis unit

households and individuals

Universe

The household section of the survey covered all households in 31 of the 32 federal states in Mexico. Colima was excluded. Institutionalised populations are excluded. The individual section covered all persons aged 18 years and older residing within individual households. As the focus of SAGE is older adults, a much larger sample of respondents aged 50 years and older was selected with a smaller comparative sample of respondents aged 18-49 years.

Kind of data

Sample survey data [ssd]

Sampling procedure

In Mexico strata were defined by locality (metropolitan, urban, rural). All 211 PSUs selected for wave 1 were included in the wave 2 sample. A sub-sample of 211 PSUs was selected from the 797 WHS PSUs for the wave 1 sample. The Basic Geo-Statistical Areas (AGEB) defined by the National Institute of Statistics (INEGI) constitutes a PSU. PSUs were selected probability proportional to three factors: a) (WHS/SAGE Wave 0 50plus): number of WHS/SAGE Wave 0 50-plus interviewed at the PSU, b) (State Population): population of the state to which the PSU belongs, c) (WHS/SAGE Wave 0 PSU at county): number of PSUs selected from the county to which the PSU belongs for the WHS/SAGE Wave 0 The first and third factors were included to reduce geographic dispersion. Factor two affords states with larger populations a greater chance of selection.

All WHS/SAGE Wave 0 individuals aged 50 years or older in the selected rural or urban PSUs and a random sample 90% of individuals aged 50 years or older in metropolitan PSUs who had been interviewed for the WHS/SAGE Wave 0 were included in the SAGE Wave 1 ''primary'' sample. The remaining 10% of WHS/SAGE Wave 0 individuals aged 50 years or older in metropolitan areas were then allocated as a ''replacement'' sample for individuals who could not be contacted or did not consent to participate in SAGE Wave 1. A systematic sample of 1000 WHS/SAGE Wave 0 individuals aged 18-49 across all selected PSUs was selected as the ''primary'' sample and 500 as a ''replacement'' sample.

This selection process resulted in a sample which had an over-representation of individuals from metropolitan strata; therefore, it was decided to increase the number of individuals aged 50 years or older from rural and urban strata. This was achieved by including individuals who had not been part of WHS/SAGE Wave 0 (which became a ''supplementary'' sample), although the household in which they lived included an individual from WHS/SAGE Wave 0. All individuals aged 50 or over were included from rural and urban ''18-49 households'' (that is, where an individual aged 18-49 was included in WHS/SAGE Wave 0) as part of the ''primary supplementary'' sample. A systematic random sample of individuals aged 50 years or older was then obtained from urban and rural households where an individual had already been selected as part of the 50 years and older or 18-49 samples. These individuals then formed part of the ''primary supplementary'' sample and the remainder (that is, those not systematically selected) were allocated to the ''replacement supplementary'' sample. Thus, all individuals aged 50 years or older who lived in households in urban and rural PSUs obtained for SAGE Wave 1 were selected as either a primary or replacement participant. A final ''replacement'' sample for the 50 and over age group was obtained from a systematic sample of all individuals aged 50 or over from households which included the individuals already selected for either the 50 and over or 18-49. This sampling strategy also provided participants who had not been included in WHS/SAGE Wave 0, but lived in a household where an individual had been part of WHS/SAGE Wave 0 (that is, the ''supplementary'' sample), in addition to follow-up of individuals who had been included in the WHS/SAGE Wave 0 sample.

Strata: Locality = 3 PSU: AGEBs = 211 SSU: Households = 6549 surveyed TSU: Individual = 6342 surveyed

Mode of data collection

Face-to-face [f2f], CAPI

Research instrument

The questionnaires were based on the SAGE Wave 1 Questionnaires with some modification and new additions, except for verbal autopsy. SAGE Wave 2 used the 2012 version of the WHO Verbal Autopsy Questionnare. SAGE Wave 1 used an adapted version of the Sample Vital Registration iwth Verbal Autopsy (SAVVY) questionnaire. A Household questionnaire was administered to all households eligible for the study. A Verbal Autopsy questionnaire was administered to 50 plus households only. In follow-up 50 plus household if the death occured since the last wave of the study and in a new 50 plus household if the death occurred in the

The systematic review focuses on the topic of minimum volume standards and the outcomes used to measure their effects. It is funded by the German Federal Ministry of Education and Research (identification number: 01KG2107).

There is an ongoing debate in health care whether a volume-outcome relationship exists. The term hospital volume-outcome relationship refers to a relationship where it is assumed that the health outcome (e.g. mortality or morbidity) is associated with hospital volume, i.e. higher hospital volume results in better health outcomes. Hospital volume is often defined by the number of cases a hospital has treated for a given procedure in a given time span. The presence of the volume-outcome relationship in surgery has been well established in the medical literature. There are also many non-surgical examples, such as dialysis, critical care, intensive care units, care for low birth weight infants, and care for people living with HIV/AIDS, where a volume-outcome relationship was found in empirical studies. However, the mechanism why higher volume results in better outcomes is not clearly understood. An explanation for volume-outcome relationships is provided by the “practice makes perfects” hypothesis. According to the “practice makes perfects” hypothesis, more experience (i.e. higher volume of interventions) results in higher proficiency and better skills, and these, in turn, result in better patient outcomes. But more theories regarding the relationship exist. Hospital volume must be considered as a proxy measure. There must be other factors that can explain the hospital volume-outcome mechanism. Specific processes of care are regarded as the most likely explanatory factors. However, processes of care are multifactorial and therefore difficult to describe. For the example of surgical interventions, many processes are involved including pre-operative and post-operative care. Structural characteristics might also have an influence on the outcome. While we focus on minimum volume standards, the results are expected to be relevant for all health system interventions aiming at centralization/regionalization.

We will consider a broad range of outcomes. The outcomes will be split into two groups (direct and indirect outcomes). For direct outcomes, we will largely follow the categorization scheme developed by the Cochrane Effective Practice and Organisation of Care (EPOC) group. As the included studies will cover a broad range of procedures, not all outcomes will be relevant for all procedures. In particular, patient outcomes will be amended depending on the procedure under study.

• Patient outcomes: (hospital) mortality, survival, morbidity, health-related quality of life, functional measures, reoperations, wound infections, bleeding, postoperative complications, readmissions, length of stay • Quality of care: adherence to clinical practice guidelines or clinical pathways, quality assurance measures • Utilisation, coverage or access: travel times, distance to hospital • Resource use: costs • Health care provider outcomes: transition frequencies (i.e. number of hospitals increasing their volume to meet minimum volume standard), number of procedures (e.g. due to broader indications) • Adverse effects or harms: any in one of the above-mentioned categories

Indirect outcomes will usually not be measured for a given procedure under study but at the health system level. As for any other health system intervention, the effects of minimum volume standards also need to be investigated at a structural level, as changes at the structural level can heavily affect any direct outcomes. These effects can be described as unintended. Nevertheless, this does not mean that they are less important. One such effect is procedure shifting (i.e. hospital focus on the delivery of new procedures). Hospitals not able to meet a minimum volume standard for a specific procedure may replace this procedure by focusing on the delivery of another procedure. Procedure shifting is acceptable unless broader indications are applied to the new procedure. Minimum volume standards might also have unintended effects on the delivery of emergency care. Hospitals not being able to deliver a procedure because of minimum volume standards might lack sufficient experience regarding emergency procedures. There can be several such relevant effects at the same time, but no consensus on them has yet been reached.

We will search the following databases to identify relevant studies: • MEDLINE (via PubMed): inception to present; • EMBASE (via EMBASE): inception to present; • CENTRAL (via Cochrane Library): inception to present; • CINAHL (via EBSCO): inception to present; • ECONLIT (via EBSCO): inception to present; • PDQ Evidence for Informed Health Policymaking (https://www.pdq-evidence.org/en/): inception to present • Health Systems Evidence (https://www.healthsystemsevidence.org/): inception to present; • Open Grey (http://www.opengrey.eu/): inception to present We will search manually for additional studies by: • cross-checking the reference lists of all included primary studies; • cross-checking the reference lists of relevant systematic reviews. We will search the following trial registries: • clinicaltrials.gov • German Clinical Study Register (DRKS) • International Clinical Trials Registry Platform (ICTRP) Furthermore, we will contact experts for additional studies. Experts will be identified by: • corresponding authors of all included primary studies; • corresponding authors of all relevant systematic reviews; • experts recently identified and contacted by the Federal Joint Committee (12) We will conduct a hand search of available abstracts from conference reports of the following conferences: • World Congress of Health Economics, Health Policy and Healthcare Management • Congress of the International Society for Evidence-Based HealthCare • Conference of the American Society of Health Economists • International Health Economics Association • Health Technology Assessment International • International Conference on Health Economics • Academy Health We will include the following study designs: • (cluster) randomised controlled trials ((C)RCTs) with at least two intervention and control sites; • non-randomised controlled trials (nRCTs) with at least two intervention and control sites; • controlled before-after (CBA) studies with at least two intervention and control sites; • interrupted time series (ITS) studies that have a clearly defined point in time when the intervention occurred and at least three data points before and three after the intervention.

We will apply no restrictions regarding language, date of publication, publication status or country of origin.

All potentially relevant hits will be imported to reference management software (e.g. EndNote). Two reviewers will independently screen titles and abstracts of all identified articles. We will retrieve the full texts of all potentially relevant articles. Full-text articles will be reviewed in detail regarding inclusion criteria by two reviewers independently. In case of disagreement, eligibility will be determined by discussion and consensus. In case of any uncertainty, we will contact the authors of the primary studies. Reference lists of the included studies will be hand screened for potential studies.

A standardized data extraction tool will be developed in excel and calibrated with the team. Using a random sample of five of the included studies, the data extraction form will be pilot-tested, and re-vised, as necessary. Data extraction will begin when high inter-rater reliability (kappa statistic ≥0.60) has been achieved. Two review authors will independently perform data extraction of the included studies using the standardized and piloted data collection form. Then, both reviewers will check each other’s versions for completeness and accuracy. Any discrepancies will be resolved by discussion. If no agreement can be reached, arbitration will be carried out by the senior researcher. We will extract data on the following items: sample size (number of included patients and hospitals); study design; patients/hospitals eligibility criteria; type of hospitals (e.g. teaching hospital); surgeon characteristics (if applicable); year(s) of data collection; country/region; data source (clinical vs. administrative); database/registry (if any); procedure or treatment; minimum volume threshold; outcomes; (unadjusted and adjusted) effect measures with corresponding confidence intervals and/or p-values; statistical models; adjusting variables.

We will use the ROBINS-I risk of bias tool, with additions for CBA and ITS study designs. The ROBINS-I tool is a risk of bias tool to assess non-randomized studies of interventions and includes seven domains. The first two domains cover confounding and selection of participants into the study, thus addressing issues before the start of the interventions that are to be compared. The third domain addresses classification of the interventions themselves. The other four domains cover issues after the start of interventions: biases due to deviations from intended interventions, missing data, measurement of outcomes, and selection of the reported result. The categories for risk of bias judgements are “Low risk”, “Moderate risk”, “Serious risk” and “Critical risk” of bias. To assess the risk of bias of cRCT and nRCT studies, we will use the RoB 2 risk of bias tool. RoB 2 is results-based and structured into a fixed set of domains of bias. Those domains include trial design, conduct, and reporting. Each domain contains a series of questions to elicit information about features of the trial that are relevant to assess the risk of bias. The proposed judgement about the risk of bias arising from each domain is generated by an algorithm, based on answers to the

The Malawi Longitudinal Study of Families and Health (MLSFH) [previous title: Malawi Diffusion and Ideational Change Project (MDICP)] is one of very few long- standing longitudinal cohort studies in a poor Sub-Saharan African (SSA) context. It provides a rare record of more than a decade of demographic, socioeconomic, and health conditions in one of the world's poorest countries. The MLSFH cohorts were selected to represent the rural population of Malawi, where the vast majority of Malawians live in conditions that are similar to those in the rural areas of other countries with high HIV prevalence: health conditions are poor, health facilities and schools are over-burdened and under-staffed, standards of living are low and nutritional needs of adults, children and the elderly are often not met. With 7 major data collection rounds between 1998 and 2012 for up to 4,000 individuals, as well as ancillary surveys and qualitative studies, the MLSFH has been a premier dataset for research on health, family dynamics, social networks, and HIV infection risks in a rural SSA context. Providing public-use data on the socioeconomic context, demographics and health of individuals and their families in Malawi over more than a decade, the MLSFH has been the basis of more than 150 publications and working papers submitted for publication. Importantly, the MLSFH has also informed health policy discussions in Malawi and elsewhere in SSA. The MLSFH/MDICP was originally developed as a sister project of the Kenya Diffusion and Ideational Change Project (KDICP), but with a larger sample and greater geographical dispersion. Both the KDICP and the MLSFH/MDICP aimed to examine the role of social interactions in changing demographic attitudes and behavior. The first two waves of the MLSFH data collected in 1998 and 2001 are archived and available for download at ICPSR-DSDR. The first two waves focused on two key empirical questions: the roles of social interactions in (1) the acceptance (or rejection) of modern contraceptive methods and of smaller ideal family size and (2) the diffusion of knowledge of AIDS symptoms and transmission mechanisms and the evaluation of acceptable strategies of protection against AIDS. More information and data for all waves of the MLSFH study can be found on the MLSFH project Web site. The MLSFH Data Web site contains instructions on how individuals can currently obtain the data (6 waves, 1998-2010). The MLSFH Cohort Profile is available as a University of Pennsylvania Population Studies Center (PSC) Working Paper. This cohort profile is the main documentation for the general study design, sampling framework, etc., and it summarizes some key findings as well.

Abstract copyright UK Data Service and data collection copyright owner.

Background:
The Millennium Cohort Study (MCS) is a large-scale, multi-purpose longitudinal dataset providing information about babies born at the beginning of the 21st century, their progress through life, and the families who are bringing them up, for the four countries of the United Kingdom. The original objectives of the first MCS survey, as laid down in the proposal to the Economic and Social Research Council (ESRC) in March 2000, were:

• to chart the initial conditions of social, economic and health advantages and disadvantages facing children born at the start of the 21st century, capturing information that the research community of the future will require
• to provide a basis for comparing patterns of development with the preceding cohorts (the National Child Development Study, held at the UK Data Archive under GN 33004, and the 1970 Birth Cohort Study, held under GN 33229)
• to collect information on previously neglected topics, such as fathers' involvement in children's care and development
• to focus on parents as the most immediate elements of the children's 'background', charting their experience as mothers and fathers of newborn babies in the year 2000, recording how they (and any other children in the family) adapted to the newcomer, and what their aspirations for her/his future may be
• to emphasise intergenerational links including those back to the parents' own childhood
• to investigate the wider social ecology of the family, including social networks, civic engagement and community facilities and services, splicing in geo-coded data when available

Additional objectives subsequently included for MCS were:

• to provide control cases for the national evaluation of Sure Start (a government programme intended to alleviate child poverty and social exclusion)
• to provide samples of adequate size to analyse and compare the smaller countries of the United Kingdom, and include disadvantaged areas of England

Further information about the MCS can be found on the Centre for Longitudinal Studies web pages.

The content of MCS studies, including questions, topics and variables can be explored via the CLOSER Discovery website.

The first sweep (MCS1) interviewed both mothers and (where resident) fathers (or father-figures) of infants included in the sample when the babies were nine months old, and the second sweep (MCS2) was carried out with the same respondents when the children were three years of age. The third sweep (MCS3) was conducted in 2006, when the children were aged five years old, the fourth sweep (MCS4) in 2008, when they were seven years old, the fifth sweep (MCS5) in 2012-2013, when they were eleven years old, the sixth sweep (MCS6) in 2015, when they were fourteen years old, and the seventh sweep (MCS7) in 2018, when they were seventeen years old.
End User Licence versions of MCS studies:
The End User Licence (EUL) versions of MCS1, MCS2, MCS3, MCS4, MCS5, MCS6 and MCS7 are held under UK Data Archive SNs 4683, 5350, 5795, 6411, 7464, 8156 and 8682 respectively. The longitudinal family file is held under SN 8172.

Sub-sample studies:
Some studies based on sub-samples of MCS have also been conducted, including a study of MCS respondent mothers who had received assisted fertility treatment, conducted in 2003 (see EUL SN 5559). Also, birth registration and maternity hospital episodes for the MCS respondents are held as a separate dataset (see EUL SN 5614).

Release of Sweeps 1 to 4 to Long Format (Summer 2020)To support longitudinal research and make it easier to compare data from different time points, all data from across all sweeps is now in a consistent format. The update affects the data from sweeps 1 to 4 (from 9 months to 7 years), which are updated from the old/wide to a new/long format to match the format of data of sweeps 5 and 6 (age 11 and 14 sweeps). The old/wide formatted datasets contained one row per family with multiple variables for different respondents. The new/long formatted datasets contain one row per respondent (per parent or per cohort member) for each MCS family. Additional updates have been made to all sweeps to harmonise variable labels and enhance anonymisation.

How to access genetic and/or bio-medical sample data from a range of longitudinal surveys:
For information on how to access biomedical data from MCS that are not held at the UKDS, see the CLS Genetic data and biological samples webpage.

Secure Access datasets:
Secure Access versions of the MCS have more restrictive access conditions than versions available under the standard End User Licence or Special Licence (see 'Access data' tab above).

Secure Access versions of the MCS...

(Note: Part of the content of this post was adapted from the original DIRECT Psychoradiology paper (https://academic.oup.com/psyrad/article/2/1/32/6604754) and REST-meta-MDD PNAS paper (http://www.pnas.org/cgi/doi/10.1073/pnas.1900390116) under CC BY-NC-ND license.)Major Depressive Disorder (MDD) is the second leading cause of health burden worldwide (1). Unfortunately, objective biomarkers to assist in diagnosis are still lacking, and current first-line treatments are only modestly effective (2, 3), reflecting our incomplete understanding of the pathophysiology of MDD. Characterizing the neurobiological basis of MDD promises to support developing more effective diagnostic approaches and treatments.An increasingly used approach to reveal neurobiological substrates of clinical conditions is termed resting-state functional magnetic resonance imaging (R-fMRI) (4). Despite intensive efforts to characterize the pathophysiology of MDD with R-fMRI, clinical imaging markers of diagnosis and predictors of treatment outcomes have yet to be identified. Previous reports have been inconsistent, sometimes contradictory, impeding the endeavor to translate them into clinical practice (5). One reason for inconsistent results is low statistical power from small sample size studies (6). Low-powered studies are more prone to produce false positive results, reducing the reproducibility of findings in a given field (7, 8). Of note, one recent study demonstrate that sample size of thousands of subjects may be needed to identify reproducible brain-wide association findings (9), calling for larger datasets to boost effect size. Another reason could be the high analytic flexibility (10). Recently, Botvinik-Nezer and colleagues (11) demonstrated the divergence in results when independent research teams applied different workflows to process an identical fMRI dataset, highlighting the effects of “researcher degrees of freedom” (i.e., heterogeneity in (pre-)processing methods) in producing disparate fMRI findings.To address these critical issues, we initiated the Depression Imaging REsearch ConsorTium (DIRECT) in 2017. Through a series of meetings, a group of 17 participating hospitals in China agreed to establish the first project of the DIRECT consortium, the REST-meta-MDD Project, and share 25 study cohorts, including R-fMRI data from 1300 MDD patients and 1128 normal controls. Based on prior work, a standardized preprocessing pipeline adapted from Data Processing Assistant for Resting-State fMRI (DPARSF) (12, 13) was implemented at each local participating site to minimize heterogeneity in preprocessing methods. R-fMRI metrics can be vulnerable to physiological confounds such as head motion (14, 15). Based on our previous work examination of head motion impact on R-fMRI FC connectomes (16) and other recent benchmarking studies (15, 17), DPARSF implements a regression model (Friston-24 model) on the participant-level and group-level correction for mean frame displacements (FD) as the default setting.In the REST-meta-MDD Project of the DIRECT consortium, 25 research groups from 17 hospitals in China agreed to share final R-fMRI indices from patients with MDD and matched normal controls (see Supplementary Table; henceforth “site” refers to each cohort for convenience) from studies approved by local Institutional Review Boards. The consortium contributed 2428 previously collected datasets (1300 MDDs and 1128 NCs). On average, each site contributed 52.0±52.4 patients with MDD (range 13-282) and 45.1±46.9 NCs (range 6-251). Most MDD patients were female (826 vs. 474 males), as expected. The 562 patients with first episode MDD included 318 first episode drug-naïve (FEDN) MDD and 160 scanned while receiving antidepressants (medication status unavailable for 84). Of 282 with recurrent MDD, 121 were scanned while receiving antidepressants and 76 were not being treated with medication (medication status unavailable for 85). Episodicity (first or recurrent) and medication status were unavailable for 456 patients.To improve transparency and reproducibility, our analysis code has been openly shared at https://github.com/Chaogan-Yan/PaperScripts/tree/master/Yan_2019_PNAS. In addition, we would like to share the R-fMRI indices of the 1300 MDD patients and 1128 NCs through the R-fMRI Maps Project (http://rfmri.org/REST-meta-MDD). These data derivatives will allow replication, secondary analyses and discovery efforts while protecting participant privacy and confidentiality.According to the agreement of the REST-meta-MDD consortium, there would be 2 phases for sharing the brain imaging data and phenotypic data of the 1300 MDD patients and 1128 NCs. 1) Phase 1: coordinated sharing, before January 1, 2020. To reduce conflict of the researchers, the consortium will review and coordinate the proposals submitted by interested researchers. The interested researchers first send a letter of intent to rfmrilab@gmail.com. Then the consortium will send all the approved proposals to the applicant. The applicant should submit a new innovative proposal while avoiding conflict with approved proposals. This proposal would be reviewed and approved by the consortium if no conflict. Once approved, this proposal would enter the pool of approved proposals and prevent future conflict. 2) Phase 2: unrestricted sharing, after January 1, 2020. The researchers can perform any analyses of interest while not violating ethics.The REST-meta-MDD data entered unrestricted sharing phase since January 1, 2020. The researchers can perform any analyses of interest while not violating ethics. Please visit Psychological Science Data Bank to download the data, and then sign the Data Use Agreement and email the scanned signed copy to rfmrilab@gmail.com to get unzip password and phenotypic information. ACKNOWLEDGEMENTSThis work was supported by the National Key R&D Program of China (2017YFC1309902), the National Natural Science Foundation of China (81671774, 81630031, 81471740 and 81371488), the Hundred Talents Program and the 13th Five-year Informatization Plan (XXH13505) of Chinese Academy of Sciences, Beijing Municipal Science & Technology Commission (Z161100000216152, Z171100000117016, Z161100002616023 and Z171100000117012), Department of Science and Technology, Zhejiang Province (2015C03037) and the National Basic Research (973) Program (2015CB351702). REFERENCES1. A. J. Ferrari et al., Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010. PLOS Medicine 10, e1001547 (2013).2. L. M. Williams et al., International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol. Trials 12, 4 (2011).3. S. J. Borowsky et al., Who is at risk of nondetection of mental health problems in primary care? J Gen Intern Med 15, 381-388 (2000).4. B. B. Biswal, Resting state fMRI: a personal history. Neuroimage 62, 938-944 (2012).5. C. G. Yan et al., Reduced default mode network functional connectivity in patients with recurrent major depressive disorder. Proc Natl Acad Sci U S A 116, 9078-9083 (2019).6. K. S. Button et al., Power failure: why small sample size undermines the reliability of neuroscience. Nat Rev Neurosci 14, 365-376 (2013).7. J. P. A. Ioannidis, Why Most Published Research Findings Are False. PLOS Medicine 2, e124 (2005).8. R. A. Poldrack et al., Scanning the horizon: towards transparent and reproducible neuroimaging research. Nat Rev Neurosci 10.1038/nrn.2016.167 (2017).9. S. Marek et al., Reproducible brain-wide association studies require thousands of individuals. Nature 603, 654-660 (2022).10. J. Carp, On the Plurality of (Methodological) Worlds: Estimating the Analytic Flexibility of fMRI Experiments. Frontiers in Neuroscience 6, 149 (2012).11. R. Botvinik-Nezer et al., Variability in the analysis of a single neuroimaging dataset by many teams. Nature 10.1038/s41586-020-2314-9 (2020).12. C.-G. Yan, X.-D. Wang, X.-N. Zuo, Y.-F. Zang, DPABI: Data Processing & Analysis for (Resting-State) Brain Imaging. Neuroinformatics 14, 339-351 (2016).13. C.-G. Yan, Y.-F. Zang, DPARSF: A MATLAB Toolbox for "Pipeline" Data Analysis of Resting-State fMRI. Frontiers in systems neuroscience 4, 13 (2010).14. R. Ciric et al., Mitigating head motion artifact in functional connectivity MRI. Nature protocols 13, 2801-2826 (2018).15. R. Ciric et al., Benchmarking of participant-level confound regression strategies for the control of motion artifact in studies of functional connectivity. NeuroImage 154, 174-187 (2017).16. C.-G. Yan et al., A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics. NeuroImage 76, 183-201 (2013).17. L. Parkes, B. Fulcher, M. Yücel, A. Fornito, An evaluation of the efficacy, reliability, and sensitivity of motion correction strategies for resting-state functional MRI. NeuroImage 171, 415-436 (2018).18. L. Wang et al., Interhemispheric functional connectivity and its relationships with clinical characteristics in major depressive disorder: a resting state fMRI study. PLoS One 8, e60191 (2013).19. L. Wang et al., The effects of antidepressant treatment on resting-state functional brain networks in patients with major depressive disorder. Hum Brain Mapp 36, 768-778 (2015).20. Y. Liu et al., Regional homogeneity associated with overgeneral autobiographical memory of first-episode treatment-naive patients with major depressive disorder in the orbitofrontal cortex: A resting-state fMRI study. J Affect Disord 209, 163-168 (2017).21. X. Zhu et al., Evidence of a dissociation pattern in resting-state default mode network connectivity in first-episode, treatment-naive major depression patients. Biological psychiatry 71, 611-617 (2012).22. W. Guo et al., Abnormal default-mode

Background: In 2019, 80% of the 7.4 million global child deaths occurred in low- and middle-income countries (LMICs). Global and regional estimates of cause of hospital death and admission in LMIC children are needed to guide global and local priority setting and resource allocation but are currently lacking. The study objective was to estimate global and regional prevalence for common causes of pediatric hospital mortality and admission in LMICs. Methods: We performed a systematic review and meta-analysis to identify LMIC observational studies published January 1, 2005-February 26, 2021. Eligible studies included: a general pediatric admission population, a cause of admission or death, and total admissions. We excluded studies with data before 2000 or without a full text. Two authors independently screened and extracted data. We performed methodological assessment using domains adapted from the Quality in Prognosis Studies tool. Data were pooled using random-effects models where possible. We reported prevalence as a proportion of cause of death or admission per 1000 admissions with 95% confidence intervals (95%CI). Findings: ur search identified 29,637 texts. After duplicate removal and screening, we analyzed 253 studies representing 21.8 million pediatric hospitalizations in 59 LMICs. All-cause pediatric hospital mortality was 4.1% [95%CI 3.4-4.7%]. The most common causes of mortality (deaths/1000 admissions) were infectious (12 [95%CI 9-14]); respiratory (9 [95%CI 5-13]); and gastrointestinal (9 [95%CI 6-11]). Common causes of admission (cases/1000 admissions) were respiratory (255 [95%CI 231-280]); infectious (214 [95%CI193-234]); and gastrointestinal (166 [95%CI 143-190]). We observed regional variation in estimates. Pediatric hospital mortality remains high in LMICs. Implications: Global child health efforts must include measures to reduce hospital mortality including basic emergency and critical care services tailored to the local disease burden. Resources are urgently needed to promote equity in child health research, support researchers, and collect high-quality data in LMICs to further guide priority setting and resource allocation. NOTE for restricted files: If you are not yet a CoLab member, please complete our membership application survey to gain access to restricted files within 2 business days. Some files may remain restricted to CoLab members. These files are deemed more sensitive by the file owner and are meant to be shared on a case-by-case basis. Please contact the CoLab coordinator at sepsiscolab@bcchr.ca or visit our website.

Abstract

The 1993 Kenya Demographic and Health Survey (KDHS) was a nationally representative survey of 7,540 women age 15-49 and 2,336 men age 20-54. The KDHS was designed to provide information on levels and trends of fertility, infant and child mortality, family planning knowledge and use, maternal and child health, and knowledge of AIDS. In addition, the male survey obtained data on men's knowledge and attitudes towards family planning and awareness of AIDS. The data are intended for use by programme managers and policymakers to evaluate and improve family planning and matemal and child health programmes. Fieldwork for the KDHS took place from mid-February until mid-August 1993. All areas of Kenya were covered by the survey, except for seven northem districts which together contain less than four percent of the country's population.

The KDHS was conducted by the National Council for Population and Development (NCPD) and the Central Bureau of Statistics of the Government of Kenya. Macro International Inc. provided financial and technical assistance to the project through the intemational Demographic and Health Surveys (DHS) contract with the U.S. Agency for International Development.

OBJECTIVES

The KDHS is intended to serve as a source of population and health data for policymakers and the research community. It was designed as a follow-on to the 1989 KDHS, a national-level survey of similar size that was implemented by the same organisations. In general, the objectives of KDHS are to: - assess the overall demographic situation in Kenya, - assist in the evaluation of the population and health programmes in Kenya, - advance survey methodology, and - assist the NCPD to strengthen and improve its technical skills to conduct demographic and health surveys.

The KDHS was specifically designed to: - provide data on the family planning and fertility behaviour of the Kenyan population to enable the NCPD to evaluate and enhance the National Family Planning Programme, - measure changes in fertility and contraceptive prevalence and at the same time study the factors which affect these changes, such as marriage patterns, urban/rural residence, availability of contraception, breastfeeding habits and other socioeconomic factors, and - examine the basic indicators of maternal and child health in Kenya.

KEY FINDINGS

The 1993 KDHS reinforces evidence of a major decline in fertility which was first revealed by the findings of the 1989 KDHS. Fertility continues to decline and family planning use has increased. However, the disparity between knowledge and use of family planning remains quite wide. There are indications that infant and under five child mortality rates are increasing, which in part might be attributed to the increase in AIDS prevalence.

Geographic coverage

The 1993 KDHS sample is national in scope, with the exclusion of all three districts in North Eastern Province and four other northern districts (Samburu and Turkana in Rift Valley Province and Isiolo and 4 Marsabit in Eastern Province). Together the excluded areas account for less than 4 percent of Kenya's population.

Analysis unit

• Household
• Women age 15-49
• Men age 20-54
• Children under five

Universe

The population covered by the 1993 KDHS is defined as the universe of all women age 15-49 in Kenya and all husband age 20-54 living in the household.

Kind of data

Sample survey data

Sampling procedure

The sample for the 1993 KDHS was national in scope, with the exclusion of all three districts in Northeastern Province and four other northern districts (Isiolo and Marsabit from Eastern Province and Samburu and Turkana from Rift Valley Province). Together the excluded areas account for less than four percent of Kenya's population. The KDHS sample points were selected from a national master sample maintained by the Central Bureau of Statistics, the third National Sample Survey and Evaluation Programme (NASSEP-3), which is an improved version of NASSEP2 used in the 1989 survey. This master sample follows a two-stage design, stratified by urban-rural residence, and within the rural stratum, by individual district. In the first stage, 1989 census enumeration areas (EAs) were selected with probability proportional to size. The selected EAs were segmented into the expected number of standard-sized clusters to form NASSEP clusters. The entire master sample consists of 1,048 rural and 325 urban ~ sample points ("clusters"). A total of 536 clusters---92 urban and 444 rural--were selected for coverage in the KDHS. Of these, 520 were successfully covered. Sixteen clusters were inaccessible for various reasons.

As in the 1989 KDHS, selected districts were oversampled in the 1993 survey in order to produce more reliable estimates for certain variables at the district level. Fifteen districts were thus targetted in the 1993 KDHS: Bungoma, Kakamega, Kericho, Kilifi, Kisii, Machakos, Meru, Murang'a, Nakuru, Nandi, Nyeri, Siaya, South Nyanza, Taita-Taveta, and Uasin Gishu; in addition, Nairobi and Mombasa were also targetted. Although six of these districts were subdivided shortly before the sample design was finalised) the previous boundaries of these districts were used for the KDHS in order to maintain comparability with the 1989 survey. About 400 rural households were selected in each of these 15 districts, just over 1000 rural households in other districts, and about 18130 households in urban areas, for a total of almost 9,000 households. Due to this oversampling, the KDHS sample is not self-weighting at the national level.

After the selection of the KDHS sample points, fieldstaff from the Central Bureau of Statistics conducted a household listing operation in January and early February 1993, immediately prior to the launching of the fieldwork. A systematic sample of households was then selected from these lists, with an average "take" of 20 households in the urban clusters and 16 households in rural clusters, for a total of 8,864 households selected. Every other household was identified as selected for the male survey, meaning that, in addition to interviewing all women age 15-49, interviewers were to also interview all men age 20-54. It was expected that the sample would yield interviews with approximately 8,000 women age 15-49 and 2,500 men age 20-54.

Mode of data collection

Face-to-face

Research instrument

Four types of questionnaires were used for the KDHS: a Household Questionnaire, a Woman's Questionnaire, a Man's Questionnaire and a Services Availability Questionnaire. The contents of these questionnaires were based on the DHS Model B Questionnaire, which is designed for use in countries with low levels of contraceptive use. Additions and modifications to the model questionnaires were made during a series of meetings organised around specific topics or sections of the questionnaires (e.g., fertility, family planning). The NCPD invited staff from a variety of organisations to attend these meetings, including the Population Studies Research Institute and other departments of the University of Nairobi, the Woman's Bureau, and various units of the Ministry of Health. The questionnaires were developed in English and then translated into and printed in Kiswahili and eight of the most widely spoken local languages in Kenya (Kalenjin, Kamba, Kikuyu, Kisii, Luhya, Luo, Meru, and Mijikenda).

a) The Household Questionnaire was used to list all the usual members and visitors of selected households. Some basic information was collected on the characteristics of each person listed, including his/her age, sex, education, and relationship to the head of the household. The main purpose of the Household Questionnaire was to identify women and men who were eligible for individual interview. In addition, information was collected about the dwelling itself, such as the source of water, type of toilet facilities, materials used to construct the house, and ownership of various consumer goods.

b) The Woman's Questionnaire was used to collect information from women aged 15-49. These women were asked questions on the following topics: Background characteristics (age, education, religion, etc.), Reproductive history, Knowledge and use of family planning methods, Antenatal and delivery care, Breastfeeding and weaning practices, Vaccinations and health of children under age five, Marriage, Fertility preferences, Husband's background and respondent's work, Awareness of AIDS. In addition, interviewing teams measured the height and weight of children under age five (identified through the birth histories) and their mothers.

c) Information from a subsample of men aged 20-54 was collected using a Man's Questionnaire. Men were asked about their background characteristics, knowledge and use of family planning methods, marriage, fertility preferences, and awareness of AIDS.

d) The Services Availability Questionnaire was used to collect information on the health and family planning services obtained within the cluster areas. One service availability questionnaire was to be completed in each cluster.

Cleaning operations

All questionnaires for the KDHS were returned to the NCPD headquarters for data processing. The processing operation consisted of office editing, coding of open-ended questions, data entry, and editing errors found by the computer programs. One NCPD officer, one data processing supervisor, one questionnaire administrator, two office editors, and initially four data entry operators were responsible for the data processing operation. Due to attrition and the need to speed up data processing, another four data entry operators were later hired

Abstract

The DPHS in Accra, Ghana was collected in May and June 2017 in slum areas across nine neighborhoods in the city. The survey focused on the impacts of a major flood event that happened in June 2015 in Accra and how the impacts related to the poverty status of households, focusing on exposure, vulnerability and capacity to recover.

This project was a collaborative effort between Global Facility for Disaster Reduction and Recovery (GFDRR), the Poverty Global Practice and Urban, Disaster Risk Management, Resilience and Land Global Practice (GPURL). The Institute of Statistical, Social and Economic Research (ISSER) of the University of Accra carried out the data collection.

Geographic coverage

Slum areas in Accra, Ghana.

Analysis unit

• Household
• Individual

Kind of data

Sample survey data [ssd]

Sampling procedure

The sample selection stratifies the targeted slums by flood proneness and the level of poverty (Erman et al., 2018) as the following:

1. Slum areas were identified by combining the definition for informal settlement used by Accra Metropolitan Assembly (AMA) and UN Habitat (2011) and a slum index score developed by Engstrom et al. (2017). Enumeration areas (EAs) were added to the sample frame if they were defined as being in a slum area using the following definition: i) they were fully inside the areas defined as informal settlement according to AMA and UN Habitat’s definition and ii) had a slum index value higher than 0.7.

2. Enumeration areas in the sample frame were categorized as low poverty and high poverty by using a neighborhood-level poverty estimate created by Engstrom et al. (2017).

3. Enumeration areas in the sample frame were also categorized as flood-prone and not flood-prone using average elevation levels in the enumeration area. High flood risk areas are defined as below 17.5 meters (based on average elevation of areas flooded in the 2015 flood) and low risk areas as above 35 meters (the elevation level, above which there were no reported flooding during the 2015 flood).

4. Four neighborhoods in which all EAs were considered high risk and 4 neighborhoods in which all EAs were considered low-risk and one neighborhood with a mix of high and low-risk EAs were selected for the sample frame. In all selected neighborhoods, all EAs were defined as slum areas. The neighborhoods selected were Korle Lagoon Area, Jamestown, Gbegbeyise and Korle Dudor as high flood risk areas, and Abeka, Accra New Town, Mamobi, and Nima as low flood risk areas and Pig Farm, which includes both high and low flood risk areas. Neighborhoods are indicated in Figure 1 in a map of Accra. This administrative division was extracted from Engstrom et al. (2013).

5. The EAs in the selected neighborhoods were stratified into four categories: i) high flood risk and high poverty incidence; ii) low flood risk and high poverty incidence; iii) high flood risk and low poverty incidence; iv) low flood risk and low poverty incidence, of all selected neighborhoods.

6. Two-stage sampling was applied; 12 EAs per strata were selected using Probability Proportion to Size (PPS) and then 20 households per selected EA were selected using random sampling after listing. The sample size was determined using power calculations.

The shapefile of the Accra neighborhoods can be found in the folder DPHS_AccraGhana_Neighbourhoods, among the resources made available. The neighborhood shapefile can be matched with the surveyed neighborhoods in the DPHS dataset (DPHS_AccraGhana_Data) through the key variable neighbourhood_code.

Reference list: ENGSTROM, R., OFIESH, C., RAIN, D., JEWELL, H., AND WEEKS, J. (2013): “Defining neighborhood boundaries for urban health research in developing countries: A case study of Accra, Ghana”, Journal of Maps, 9(1), 36-42. ENGSTROM, R., D., PAVELESKU, T., TANAKA, A., AND WAMBILE (2017): “Monetary and non-monetary poverty in urban slums in Accra: Combining geospatial data and machine learning to study urban poverty,” Work in Progress, The World Bank. ERMAN, A., MOTTE, E., GOYAL, R., ASARE, A., TAKAMATSU, S., CHEN, X., MALGIOGLIO, S., SKINNER, A., YOSHIDA, N., AND HALLEGATTE, S. (2018): “The road to recovery: the role of poverty in the exposure, vulnerability and resilience to floods in Accra,” Policy Research Working Paper; No. 8469. World Bank, Washington, DC.

Mode of data collection

Computer Assisted Personal Interview [capi]

Research instrument

The survey questionnaire consists of 14 sections that were used to collect the survey data. See the attached questionnaire.

Cleaning operations

The following data editing was done for anonymization purpose: • Precise location data, such as GPS coordinates, were dropped • Identifying information, such as name, birth date and phone number were dropped • Furthermore, the number of reported religions was reduced from 8 to 3 categories, the number of ethnicities from 9 to 4 categories and household size exceeding seven household members was categorized as “above 7 members”. • Household member information for 7th member and above was dropped to avoid reconstruction of the household size variable.