The U.S. federal funds effective rate underwent a dramatic reduction in early 2020 in response to the COVID-19 pandemic. The rate plummeted from 1.58 percent in February 2020 to 0.65 percent in March, and further decreased to 0.05 percent in April. This sharp reduction, accompanied by the Federal Reserve's quantitative easing program, was implemented to stabilize the economy during the global health crisis. After maintaining historically low rates for nearly two years, the Federal Reserve began a series of rate hikes in early 2022, with the rate moving from 0.33 percent in April 2022 to 5.33 percent in August 2023. The rate remained unchanged for over a year, before the Federal Reserve initiated its first rate cut in nearly three years in September 2024, bringing the rate to 5.13 percent. By December 2024, the rate was cut to 4.48 percent, signaling a shift in monetary policy in the second half of 2024. In January 2025, the Federal Reserve implemented another cut, setting the rate at 4.33 percent, which remained unchanged throughout the following months. What is the federal funds effective rate? The U.S. federal funds effective rate determines the interest rate paid by depository institutions, such as banks and credit unions, that lend reserve balances to other depository institutions overnight. Changing the effective rate in times of crisis is a common way to stimulate the economy, as it has a significant impact on the whole economy, such as economic growth, employment, and inflation. Central bank policy rates The adjustment of interest rates in response to the COVID-19 pandemic was a coordinated global effort. In early 2020, central banks worldwide implemented aggressive monetary easing policies to combat the economic crisis. The U.S. Federal Reserve's dramatic reduction of its federal funds rate - from 1.58 percent in February 2020 to 0.05 percent by April - mirrored similar actions taken by central banks globally. While these low rates remained in place throughout 2021, mounting inflationary pressures led to a synchronized tightening cycle beginning in 2022, with central banks pushing rates to multi-year highs. By mid-2024, as inflation moderated across major economies, central banks began implementing their first rate cuts in several years, with the U.S. Federal Reserve, Bank of England, and European Central Bank all easing monetary policy.
The Federal Reserve's balance sheet has undergone significant changes since 2007, reflecting its response to major economic crises. From a modest *** trillion U.S. dollars at the end of 2007, it ballooned to approximately **** trillion U.S. dollars by June 2025. This dramatic expansion, particularly during the 2008 financial crisis and the COVID-19 pandemic - both of which resulted in negative annual GDP growth in the U.S. - showcases the Fed's crucial role in stabilizing the economy through expansionary monetary policies. Impact on inflation and interest rates The Fed's expansionary measures, while aimed at stimulating economic growth, have had notable effects on inflation and interest rates. Following the quantitative easing in 2020, inflation in the United States reached ***** percent in 2022, the highest since 1991. However, by *************, inflation had declined to *** percent. Concurrently, the Federal Reserve implemented a series of interest rate hikes, with the rate peaking at **** percent in ***********, before the first rate cut since ************** occurred in **************. Financial implications for the Federal Reserve The expansion of the Fed's balance sheet and subsequent interest rate hikes have had significant financial implications. In 2023, the Fed reported a negative net income of ***** billion U.S. dollars, a stark contrast to the ***** billion U.S. dollars profit in 2022. This unprecedented shift was primarily due to rapidly rising interest rates, which caused the Fed's interest expenses to soar to over *** billion U.S. dollars in 2023. Despite this, the Fed's net interest income on securities acquired through open market operations reached a record high of ****** billion U.S. dollars in the same year.
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
High-frequency changes in interest rates around FOMC announcements are a standard method of measuring monetary policy shocks. However, some recent studies have documented puzzling effects of these shocks on private-sector forecasts of GDP, unemployment, or inflation that are opposite in sign to what standard macroeconomic models would predict. This evidence has been viewed as supportive of a "Fed information effect" channel of monetary policy, whereby an FOMC tightening (easing) communicates that the economy is stronger (weaker) than the public had expected. We show that these empirical results are also consistent with a "Fed response to news" channel, in which incoming, publicly available economic news causes both the Fed to change monetary policy and the private sector to revise its forecasts. We provide substantial new evidence that distinguishes between these two channels and strongly favors the latter; for example, (i) regressions that include the previously omitted public economic news, (ii) a new survey that we conduct of Blue Chip forecasters, and (iii) high-frequency financial market responses to FOMC announcements all suggest that the Fed and private sector are simply responding to the same public news, with relatively little role for a "Fed information effect".
The Federal Reserve's balance sheet ballooned following its announcement to carry out quantitative easing to increase the liquidity of U.S. banks in early 2020. The balance sheet continued to grow in the following period as well, with a downward trend in 2023. As of February 29, 2024, the Fed's balance sheet amounted to roughly 7.6 trillion U.S. dollars. The most drastic increase in the observed period took place in the first half of 2020. This measure was taken to increase the money supply and stimulate economic growth in the wake of the damage caused by the COVID-19 pandemic. The Federal Reserve was not the only institution that implemented an expansionary monetary policy in response to the pandemic. For instance, the European Central Bank expanded its money supply in March 2020 and kept doing so over the following months. How do central banks increase the amount of money in circulation? Central banks can increase the money circulating in the economy in many ways. For instance, they can decrease banks’ reserve requirements to stimulate lending or decrease the interest rates to reduce the cost of borrowing for commercial banks. Alternatively, central banks can engage in open market operations (OMO) and buy securities such as government bonds from commercial banks or institutions. By conducting open market operations, the Federal Reserve expanded its balance sheet by seven trillion U.S. dollars between 2007 and 2023. All these measures aim to increase bank loans to entrepreneurs and consumers in order to stimulate employment and economic growth. Impact of COVID-19 on the U.S. economy The COVID-19 pandemic had a tremendous impact on national economies worldwide, and the United States was no exception. During the early months of the crisis, many lost their jobs, mostly those in lower-income categories. As a consequence, many Americans found it difficult to pay their rent and cover basic household expenses. Furthermore, in April 2022, most small business owners claimed that the pandemic had a large or moderate negative effect on their businesses. Overall, the gross domestic product (GDP) of the United States decreased by roughly 2.2 percent in 2020. In the following years, however, it increased notably, surpassing 25 trillion U.S. dollars in 2022.
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
The aim of this study is to determine whether the stock indices of some developed and developing countries react similarly to the price movements in the Dow Jones Industrial Average (DJIA). In this study, the impact of DJIA on other indices during the 2008 global financial crisis, was explored by using the Vector Error Correction Model. The data used was analyzed in two periods: (1) the expansionary period; and (2) the contractionary period of the FED's policies. The results of the analysis indicate that the developed and emerging stock markets react differently to the DJIA. The results include important findings for decisions by financial investors and policy makers.
https://www.icpsr.umich.edu/web/ICPSR/studies/34706/termshttps://www.icpsr.umich.edu/web/ICPSR/studies/34706/terms
The financial crisis of 2007-09 is widely viewed as the worst financial disruption since the Great Depression of 1929-1933. However, the accompanying economic recession was mild compared with the Great Depression, though severe by postwar standards.
The U.S. federal funds rate peaked in 2023 at its highest level since the 2007-08 financial crisis, reaching 5.33 percent by December 2023. A significant shift in monetary policy occurred in the second half of 2024, with the Federal Reserve implementing regular rate cuts. By December 2024, the rate had declined to 4.48 percent. What is a central bank rate? The federal funds rate determines the cost of overnight borrowing between banks, allowing them to maintain necessary cash reserves and ensure financial system liquidity. When this rate rises, banks become more inclined to hold rather than lend money, reducing the money supply. While this decreased lending slows economic activity, it helps control inflation by limiting the circulation of money in the economy. Historic perspective The federal funds rate historically follows cyclical patterns, falling during recessions and gradually rising during economic recoveries. Some central banks, notably the European Central Bank, went beyond traditional monetary policy by implementing both aggressive asset purchases and negative interest rates.
https://fred.stlouisfed.org/legal/#copyright-public-domainhttps://fred.stlouisfed.org/legal/#copyright-public-domain
Graph and download economic data for 10-Year Real Interest Rate (REAINTRATREARAT10Y) from Jan 1982 to Jul 2025 about 10-year, interest rate, interest, real, rate, and USA.
The inflation rate in the United States declined significantly between June 2022 and May 2025, despite rising inflationary pressures towards the end of 2024. The peak inflation rate was recorded in June 2022, at *** percent. In August 2023, the Federal Reserve's interest rate hit its highest level during the observed period, at **** percent, and remained unchanged until September 2024, when the Federal Reserve implemented its first rate cut since September 2021. By January 2025, the rate dropped to **** percent, signalling a shift in monetary policy. What is the Federal Reserve interest rate? The Federal Reserve interest rate, or the federal funds rate, is the rate at which banks and credit unions lend to and borrow from each other. It is one of the Federal Reserve's key tools for maintaining strong employment rates, stable prices, and reasonable interest rates. The rate is determined by the Federal Reserve and adjusted eight times a year, though it can be changed through emergency meetings during times of crisis. The Fed doesn't directly control the interest rate but sets a target rate. It then uses open market operations to influence rates toward this target. Ways of measuring inflation Inflation is typically measured using several methods, with the most common being the Consumer Price Index (CPI). The CPI tracks the price of a fixed basket of goods and services over time, providing a measure of the price changes consumers face. At the end of 2023, the CPI in the United States was ****** percent, up from ****** a year earlier. A more business-focused measure is the producer price index (PPI), which represents the costs of firms.
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
Philadelphia Fed Manufacturing Index in the United States increased to 15.90 points in July from -4 points in June of 2025. This dataset provides the latest reported value for - United States Philadelphia Fed Manufacturing Index - plus previous releases, historical high and low, short-term forecast and long-term prediction, economic calendar, survey consensus and news.
In May 2025, global inflation rates and central bank interest rates showed significant variation across major economies. Most economies initiated interest rate cuts from mid-2024 due to declining inflationary pressures. The U.S., UK, and EU central banks followed a consistent pattern of regular rate reductions throughout late 2024. In early 2025, Russia maintained the highest interest rate at 20 percent, while Japan retained the lowest at 0.5 percent. Varied inflation rates across major economies The inflation landscape varies considerably among major economies. China had the lowest inflation rate at -0.1 percent in May 2025. In contrast, Russia maintained a high inflation rate of 9.9 percent. These figures align with broader trends observed in early 2025, where China had the lowest inflation rate among major developed and emerging economies, while Russia's rate remained the highest. Central bank responses and economic indicators Central banks globally implemented aggressive rate hikes throughout 2022-23 to combat inflation. The European Central Bank exemplified this trend, raising rates from 0 percent in January 2022 to 4.5 percent by September 2023. A coordinated shift among major central banks began in mid-2024, with the ECB, Bank of England, and Federal Reserve initiating rate cuts, with forecasts suggesting further cuts through 2025 and 2026.
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
Effect of microplastic ingestion on heterotrophic dinoflagellate functional responses
https://www.icpsr.umich.edu/web/ICPSR/studies/1299/termshttps://www.icpsr.umich.edu/web/ICPSR/studies/1299/terms
A primary purpose of the Federal Reserve Act of 1913 was to prevent banking panics by establishing the Federal Reserve System to function as a lender of last resort. Other types of financial crisis require a similar response, however, and the Federal Reserve has repeatedly used its capacity to generate liquidity to insulate the economy from crises in financial markets. The Fed's response to the terrorist attacks of September 11, 2001, is the most recent example of this. This paper reviews the Fed's responses to crises and potential crises in financial markets: the stock market crash of 1987, the Russian default, and the September 11th attacks.
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
We use the yield curve to predict future GDP growth and recession probabilities. The spread between short- and long-term rates typically correlates with economic growth. Predications are calculated using a model developed by the Federal Reserve Bank of Cleveland. Released monthly.
https://fred.stlouisfed.org/legal/#copyright-public-domainhttps://fred.stlouisfed.org/legal/#copyright-public-domain
Graph and download economic data for Personal Saving Rate (PSAVERT) from Jan 1959 to Jun 2025 about savings, personal, rate, and USA.
https://fred.stlouisfed.org/legal/#copyright-public-domainhttps://fred.stlouisfed.org/legal/#copyright-public-domain
Graph and download economic data for 31) To the Extent That the Price or Nonprice Terms Applied to Separately Managed Accounts Established with Investment Advisers Have Tightened or Eased Over the Past Three Months (as Reflected in Your Responses to Questions 29 and 30), What Are the Most Important Reasons for the Change?| A. Possible Reasons for Tightening | 3. Adoption of More-Stringent Market Conventions (That Is, Collateral Terms and Agreements, ISDA Protocols). | Answer Type: First In Importance (CTQ31A3MINR) from Q1 2012 to Q2 2025 about ease, collateral, marketable, separations, change, accounts, management, 3-month, investment, price, and USA.
During the financial crisis of 2007-10, the Federal Reserve (Fed) served as a global lender of last resort by establishing currency swap agreements with 14 foreign central banks, including several in East Asia. These agreements were controversial internationally because the Fed selectively established swaps with some central banks and not others, raising concerns about access to the Fed’s dollar-creating facilities. Within the U.S. Congress, the swaps were controversial because they appeared to be a new and unauthorized form of foreign aid. I analyze both the Fed’s decision to establish swap lines with certain central banks and the congressional response to these arrangements. I find that the Fed was more likely to establish swaps with central banks whose jurisdictions were important to U.S. commercial banks, suggesting that the Fed discriminated in ways that served U.S. interests. To analyze the congressional reaction to the foreign currency swaps, I examine voting in the House of Representatives on a legislative proposal known as “Audit the Fed” that would end the Fed's confidentiality about the foreign central banks it supports and reduce its political independence more broadly. I find that campaign contributions from commercial banks to representatives are negatively correlated with voting “yes” on this proposal. I also find that right-wing representatives are much more likely to support this proposal than left-wing representatives, which suggests that new congressional coalitions are forming on the role of the Fed in the (global) economy.
https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy
The global glove box feeding station market size is projected to grow from USD 1.45 billion in 2023 to USD 2.78 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.5% during the forecast period. This growth is driven by increasing demand in pharmaceutical and biotechnology sectors due to stringent contamination control regulations.
One of the primary growth factors for the glove box feeding station market is the rising emphasis on contamination control in critical research and industrial processes. With stringent regulations and standards imposed by healthcare and safety organizations, the need to maintain sterile environments has become paramount. This is particularly evident in the pharmaceutical and biotechnology industries, where even the slightest contamination can compromise product integrity and patient safety. The increasing R&D investments in these sectors further fuel the demand for advanced glove box feeding stations that ensure an uncontaminated environment.
Moreover, the surge in chemical research and electronics manufacturing is another crucial driver for this market. Chemical research often involves handling hazardous substances that require a contained environment to prevent exposure to researchers and the environment. Similarly, the electronics industry necessitates environments free from particulate contamination to ensure the integrity and performance of sensitive electronic components. The growing trend of miniaturization in electronics further amplifies the need for highly controlled environments, thereby boosting the demand for glove box feeding stations.
Technological advancements and innovations in material science and engineering are also expected to propel the market. Manufacturers are focusing on developing glove boxes with enhanced features such as improved ergonomic designs, better visibility, and advanced filtration systems to meet the diverse needs of end-users. The integration of automation and digital monitoring systems into glove box feeding stations is another trend gaining traction. These innovations not only enhance operational efficiency but also ensure higher accuracy and reliability, thus driving market growth.
Regionally, North America holds a significant share of the glove box feeding station market, attributed to the presence of a robust pharmaceutical and biotechnology sector, coupled with stringent regulatory frameworks. Asia Pacific is anticipated to witness the fastest growth, driven by expanding industrial and research activities, particularly in countries like China and India. The increasing number of research laboratories and growing focus on chemical and electronics manufacturing in these regions are major contributors to this growth.
The integration of Laboratory Reaction Station technology is becoming increasingly significant in the context of glove box feeding stations. These stations are pivotal in conducting controlled chemical reactions, particularly in environments where contamination control is crucial. Laboratory reaction stations offer precise control over reaction parameters such as temperature, pressure, and mixing, which are essential for achieving desired outcomes in chemical synthesis and research. The synergy between glove box feeding stations and laboratory reaction stations enhances the capability to conduct sensitive experiments while maintaining a contamination-free environment. This integration is particularly beneficial in fields like pharmaceuticals and biotechnology, where the purity and integrity of products are paramount.
The single glove box feeding station segment is expected to maintain a steady growth rate during the forecast period. These stations are predominantly used in small-scale laboratories and research facilities where space and budget constraints are significant considerations. The compact design and cost-effectiveness of single glove box feeding stations make them an ideal choice for academic institutions and research laboratories that require high levels of contamination control without extensive infrastructure investments. Additionally, the ease of installation and operation associated with single glove box feeding stations further enhances their adoption in
Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
License information was derived automatically
BACKGROUND Chagas disease is highly prevalent in Latin America, and vector control is the most effective control strategy to date. We have previously shown that liquid chromatography tandem mass spectrometry (LC-MS/MS) is a valuable tool for identifying triatomine vector blood meals. OBJECTIVES The purpose of this study was to determine blood meal detection ability as a function of method [polymerase chain reaction (PCR) vs. LC-MS/MS], time since feeding, and the effect of molting in mouse-fed triatomine insect vectors targeting hemoglobin and albumin proteins with LC-MS/MS and short interspersed nuclear elements (SINE)-based PCR. METHODS We experimentally fed Triatoma protracta on mice and used LC-MS/MS to detect hemoglobin and albumin peptides over time post-feeding and post-molting (≤ 12 weeks). We compared LC-MS/MS results with those of a standard PCR method based on SINEs. FINDINGS Hemoglobin-based LC-MS/MS detected blood meals most robustly at all time points post-feeding. Post-molting, no blood meals were detected with PCR, whereas LC-MS/MS detected mouse hemoglobin and albumin up to 12 weeks. MAIN CONCLUSIONS In our study, the hemoglobin signature in the insect abdomen lasted longer than that of albumin and DNA. LC-MS/MS using hemoglobin shows promise for identifying triatomine blood meals over long temporal scales and even post-molting. Clarifying the frequency of blood-feeding on different hosts can foster our understanding of vector behavior and may help devise sounder disease-control strategies, including Ecohealth (community based ecosystem management) approaches.
https://spdx.org/licenses/CC0-1.0.htmlhttps://spdx.org/licenses/CC0-1.0.html
Developing organisms typically mature earlier and at larger sizes in favorable growth conditions, while in rarer cases maturity is delayed. The rarer reaction norm is easily accommodated by general life history models, whereas the common pattern is not. Theory suggests that a solution to this paradox lies in the existence of developmental thresholds that define the minimum size at which maturation or metamorphosis can commence, and in the evolution of these threshold sizes in response to environmental variation. For example, more ephemeral environments might favor the evolution of smaller thresholds, enabling earlier maturation. The threshold model makes two unique and untested predictions; first, reaction norms for age and size should steepen, and even change sign, with decreases in the threshold size, and second, food reductions at sizes below the threshold should delay maturation, while those occurring after the threshold should accelerate maturation. We test these predictions by performing targeted food manipulations in a suite of five damselfly species, which theory suggest should differ in threshold size. The results provide strong support for the threshold model’s predictions. In all species, early food reductions delayed maturation, while late reductions accelerated maturation. Reaction norms were steeper, and the effect of food reductions changed from decelerating to accelerating at a much smaller size in fast-developing species from ephemeral habitats. These results support the view that developmental thresholds can account for the widespread observation of negative correlations between age and size at maturity. Moreover, evolution of the threshold appears to be both central to the observed diversity of reaction norms for age and size at maturity, and is predictable.
Methods We conducted a common garden experiment using five species of damselflies from Eastern North America: Enallagma doubledayi, E. pollutum, Ischnura ramburii, I. hastata and I. posita (Odonata: Coenagrionidae). Larvae used in the experiment were hatched from eggs laid by field-collected females sampled at sites in North Carolina, Georgia and Florida, USA, in June and July, 2014. We reared multiple family groups of each species from egg to adult in the laboratory to test for the effect of food reductions within species and for divergence in developmental thresholds and reaction norms among species. One subset of larvae from each family experienced high food levels during the entire experiment, whereas random subsets of individuals from each family were switched from high to low food levels at different body sizes. From the beginning of the experiment, larvae were fed Artemia nauplii ad libitum six days a week (174±34 nauplii per feeding, mean ± 1SD, n=43 random food doses), which represents our high food level treatment. At set intervals, random subsets of individuals from each family were switched from high to low food levels. After the switch, low food individuals were fed three days a week (Monday, Wednesday, Friday) for the remainder of the experiment using the same amount of nauplii as high food larvae.
To estimate larval size, we measured the head width (maximum distance between the distal parts of the eyes) of living larvae. We converted larval head widths to dry weights by killing ~4 individuals per week and species, drying them for 48h, and weighing them to the nearest 0.001mg. With this data, we established allometric relationships between head width and dry weight for each species. Adult size was estimated by drying and weighing individuals that had emerged and hardened for 24h. For individuals that did not fully emerge from their exuvium, we weighed the adults together with their exuvia. To enable direct comparisons, we weighed the exuviae of successfully emerged individuals and estimated the relationship between the total dry weight (adult + exuvium) and adult dry weight (excluding the exuvium) for each species. Using these relationships, we converted total dry weights into adult dry weights for individuals that were measured with their exuviae. The dataset presented here only include data on adult dry weight (excluding exuviae) estimated in this way.
The U.S. federal funds effective rate underwent a dramatic reduction in early 2020 in response to the COVID-19 pandemic. The rate plummeted from 1.58 percent in February 2020 to 0.65 percent in March, and further decreased to 0.05 percent in April. This sharp reduction, accompanied by the Federal Reserve's quantitative easing program, was implemented to stabilize the economy during the global health crisis. After maintaining historically low rates for nearly two years, the Federal Reserve began a series of rate hikes in early 2022, with the rate moving from 0.33 percent in April 2022 to 5.33 percent in August 2023. The rate remained unchanged for over a year, before the Federal Reserve initiated its first rate cut in nearly three years in September 2024, bringing the rate to 5.13 percent. By December 2024, the rate was cut to 4.48 percent, signaling a shift in monetary policy in the second half of 2024. In January 2025, the Federal Reserve implemented another cut, setting the rate at 4.33 percent, which remained unchanged throughout the following months. What is the federal funds effective rate? The U.S. federal funds effective rate determines the interest rate paid by depository institutions, such as banks and credit unions, that lend reserve balances to other depository institutions overnight. Changing the effective rate in times of crisis is a common way to stimulate the economy, as it has a significant impact on the whole economy, such as economic growth, employment, and inflation. Central bank policy rates The adjustment of interest rates in response to the COVID-19 pandemic was a coordinated global effort. In early 2020, central banks worldwide implemented aggressive monetary easing policies to combat the economic crisis. The U.S. Federal Reserve's dramatic reduction of its federal funds rate - from 1.58 percent in February 2020 to 0.05 percent by April - mirrored similar actions taken by central banks globally. While these low rates remained in place throughout 2021, mounting inflationary pressures led to a synchronized tightening cycle beginning in 2022, with central banks pushing rates to multi-year highs. By mid-2024, as inflation moderated across major economies, central banks began implementing their first rate cuts in several years, with the U.S. Federal Reserve, Bank of England, and European Central Bank all easing monetary policy.