The burden of influenza in the United States can vary from year to year depending on which viruses are circulating, how many people receive an influenza vaccination, and how effective the vaccination is in that particular year. During the 2023-2024 flu season, around 28,000 people lost their lives to the disease. Although most people recover from influenza without needing medical care, the disease can be deadly among young children, the elderly, and those with weakened immune systems or chronic illnesses. Deaths due to influenza Even though most people recover from influenza without medical care, influenza and pneumonia can be deadly, especially for older people and those with certain preexisting conditions. Influenza is a common cause of pneumonia and although most cases of influenza do not develop into pneumonia, those that do are often more severe and more deadly. Deaths due to influenza are most common among the elderly, with a mortality rate of around 32 per 100,000 population during the 2023-2024 flu season. In comparison, the mortality rate for those aged 50 to 64 years was 9.1 per 100,000 population. Flu vaccinations The most effective way to prevent influenza is to receive an annual influenza vaccination. These vaccines have proven to be safe and are usually cheap and easily accessible. Nevertheless, every year a large share of the population in the United States still fails to get vaccinated against influenza. For example, in the 2022-2023 flu season, only 35 percent of those aged 18 to 49 years received a flu vaccination. Unsurprisingly, children and the elderly are the most likely to get vaccinated. It is estimated that during the 2022-2023 flu season, vaccinations prevented over 929 thousand influenza cases among children aged 6 months to 4 years.

The mortality rate from influenza in the United States is by far highest among those aged 65 years and older. During the 2023-2024 flu season, the mortality rate from influenza for this age group was around 32.1 per 100,000 population. The burden of influenza The impact of influenza in the U.S. varies from season to season, but in the 2023-2024 flu season, there were an estimated 40 million cases. These cases resulted in around 470,000 hospitalizations. Although most people recover from influenza without requiring medical treatment, the disease can be deadly for young children, the elderly, and those with weakened immune systems or chronic illnesses. During the 2023-2024 flu season, around 28,000 people in the U.S. lost their lives due to influenza. Impact of vaccinations The most effective way to prevent influenza is to receive an annual vaccination at the beginning of flu season. Flu vaccines are safe and can greatly reduce the burden of the disease. During the 2022-2023 flu season, vaccinations prevented around 2,479 deaths among those aged 65 years and older. Although flu vaccines are usually cheap and easily accessible, every year a large share of the population in the U.S. still does not get vaccinated. For example, during the 2022-2023 flu season, only about 35 percent of those aged 18 to 49 years received a flu vaccination.

Influenza and pneumonia caused around 10.9 deaths in the U.S. per 100,000 population in 2023. Influenza, or the flu, is a viral infection that is highly contagious and especially common in the winter season. Influenza is a common cause of pneumonia, although most cases of the flu do not develop into pneumonia. Pneumonia is an infection or inflammation of the lungs and is particularly deadly among young children and the elderly. Influenza cases Influenza is very common in the United States, with an estimated 40 million cases reported in 2023-2024. Common symptoms of the flu include cough, fever, runny or stuffy nose, sore throat and headache. Symptoms can be mild but can also be severe enough to require medical attention. In 2023-2024, there were around 18 million influenza-related medical visits in the United States. Prevention To prevent contracting the flu, people can take everyday precautions such as regularly washing their hands and avoiding those who are sick, but the best way to prevent the flu is by receiving the flu vaccination every year. Receiving a flu vaccination is especially important for young children and the elderly, as they are most susceptible to flu complications and associated death. In 2024, around 70 percent of those aged 65 years and older received a flu vaccine, while only 33 percent of those aged 18 to 49 years had done so.

Australia Influenza Mortality jumped by 8% in 2019, from a year earlier.

Deaths counts for influenza, pneumonia, and COVID-19 reported to NCHS by week ending date, by state and HHS region, and age group.

Provisional counts of the number of death occurrences in England and Wales due to coronavirus (COVID-19) and influenza and pneumonia, by age, sex and place of death.

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Following the outbreak of the H1N1 influenza pandemic of 1918, which came to be known as the Spanish Flu, the number of deaths due to influenza and pneumonia soared. Pneumonia was caused either by the influenza or by a bacterial superinfection that took hold due to the patient's weakened state as a result of the influenza, for this reason, influenza deaths and pneumonia deaths were recorded together as one. Pennsylvania had the highest mortality rate due to the pandemic, where there were over 880 fatalities per 100,000 people; meaning that approximately 0.9 percent of the state's population died from the Spanish Flu pandemic in 1918.

When compared with the 1915 mortality rates, many states, such as California and Pennsylvania, saw their mortality rate due to influenza and pneumonia increase five-fold by 1818, which was the worst year of the pandemic. While the mortality rate decreased significantly in the year 1919, there was no US state where it fell to it's pre-pandemic level, and the 1919 mortality rate was still double the pre-pandemic rate in some states such as California, South Carolina and Washington.

Influenza death rates by county, all races (includes Hispanic/Latino), all sexes, all ages, 2019-2023. Death data were provided by the National Vital Statistics System. Death rates (deaths per 100,000 population per year) are age-adjusted to the 2000 US standard population (20 age groups: <1, 1-4, 5-9, ... , 80-84, 85-89, 90+). Rates calculated using SEER*Stat. Population counts for denominators are based on Census populations as modified by the National Cancer Institute. The US Population Data File is used for mortality data. The Average Annual Percent Change is based onthe APCs calculated by the Joinpoint Regression Program (Version 4.9.0.0). Due to data availability issues, the time period used in the calculation of the joinpoint regression model may differ for selected counties. Counties with a (3) after their name may have their joinpoint regresssion model calculated using a different time period due to data availability issues.

This file contains the provisional percent of total deaths by week for COVID-19, Influenza, and Respiratory Syncytial Virus for deaths occurring among residents in the United States. Provisional data are based on non-final counts of deaths based on the flow of mortality data in National Vital Statistics System.

this graph was created in OurDataWorld, R , Loocker and Tableau

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Introduction: Seasonal influenza, often perceived as a common illness, carries a significant global burden, claiming hundreds of thousands of lives annually. Despite advancements in healthcare and vaccination efforts, the flu remains a formidable threat, particularly affecting vulnerable populations such as infants and the elderly. This article delves into the intricacies of influenza-related mortality, examining regional disparities, contributing factors, and the implications for public health.

The Global Landscape of Influenza Mortality: Data from the Global Pandemic Mortality Project II sheds light on the magnitude of influenza-related deaths, drawing from surveillance metrics spanning from 2002 to 2011. These estimates, while informative, underscore the challenge of accurately gauging mortality rates, especially in low-income countries where testing and mortality records may be lacking.

Respiratory Symptoms and Beyond: The conventional understanding of influenza-related fatalities primarily revolves around respiratory complications. Pneumonia and other respiratory ailments serve as prominent causes of death, contributing to the staggering toll of 400,000 lives claimed annually. However, it is imperative to acknowledge that the impact of influenza extends beyond respiratory symptoms. Complications such as strokes and heart attacks, though not explicitly captured in mortality estimates, further amplify the disease's lethality, warranting comprehensive preventive measures.

Vulnerability Across Age Groups: Influenza's lethality is not uniform across age demographics. Infants and the elderly emerge as the most susceptible cohorts, bearing the brunt of severe complications and mortality. Among individuals aged over 65, the mortality rate stands at approximately 31 per 100,000 in Europe alone, reflecting the disproportionate impact on older populations. The interplay of age-related factors, including weakened immune responses and underlying health conditions, exacerbates the severity of influenza outcomes among these groups.

Regional Disparities and Determinants: A notable aspect of influenza mortality lies in its disparate distribution across regions. While Europe and North America exhibit relatively lower death rates, countries in South America, Africa, and South Asia grapple with higher mortality burdens. This regional divide underscores the complex interplay of socio-economic factors, healthcare accessibility, and vaccination coverage. Poverty, inadequate healthcare infrastructure, and suboptimal vaccination rates converge to heighten vulnerability to influenza-related complications, amplifying mortality rates in resource-constrained settings.

Implications for Public Health: The revelation of significant regional differentials in influenza mortality necessitates a tailored approach to public health interventions. Strengthening healthcare systems, particularly in low-income regions, is paramount to bolstering surveillance, enhancing diagnostic capabilities, and facilitating timely interventions. Furthermore, targeted vaccination campaigns, coupled with education initiatives, hold promise in mitigating influenza's toll, especially among vulnerable populations. Addressing socio-economic disparities and bolstering healthcare resilience emerge as pivotal strategies in fortifying global defenses against seasonal influenza.

Conclusion: Seasonal influenza, often underestimated in its impact, exacts a substantial toll on global health each year. The multifaceted nature of influenza-related mortality underscores the need for a nuanced understanding and comprehensive mitigation strategies. By addressing regional disparities, prioritizing vulnerable populations, and fortifying healthcare systems, the global community can strive towards mitigating the burden of seasonal influenza, safeguarding lives, and fostering resilient health systems for generations to come.

BackgroundThe historical Japanese influenza vaccination program targeted at schoolchildren provides a unique opportunity to evaluate the indirect benefits of vaccinating high-transmitter groups to mitigate disease burden among seniors. Here we characterize the indirect mortality benefits of vaccinating schoolchildren based on data from Japan and the US. MethodsWe compared age-specific influenza-related excess mortality rates in Japanese seniors aged ≥65 years during the schoolchildren vaccination program (1978–1994) and after the program was discontinued (1995–2006). Indirect vaccine benefits were adjusted for demographic changes, socioeconomics and dominant influenza subtype; US mortality data were used as a control. ResultsWe estimate that the schoolchildren vaccination program conferred a 36% adjusted mortality reduction among Japanese seniors (95%CI: 17–51%), corresponding to ∼1,000 senior deaths averted by vaccination annually (95%CI: 400–1,800). In contrast, influenza-related mortality did not change among US seniors, despite increasing vaccine coverage in this population. ConclusionsThe Japanese schoolchildren vaccination program was associated with substantial indirect mortality benefits in seniors.

This file contains the complete set of data reported to 122 Cities Mortality Reposting System. The system was retired as of 10/6/2016. While the system was running each week, the vital statistics offices of 122 cities across the United States reported the total number of death certificates processed and the number of those for which pneumonia or influenza was listed as the underlying or contributing cause of death by age group (Under 28 days, 28 days - 1 year, 1-14 years, 15-24 years, 25-44 years, 45-64 years, 65-74 years, 75-84 years, and - 85 years). U:Unavailable. - : No reported cases.* Mortality data in this table were voluntarily reported from 122 cities in the United States, most of which have populations of >100,000. A death is reported by the place of its occurrence and by the week that the death certificate was filed. Fetal deaths are not included. Total includes unknown ages. More information on Flu Activity & Surveillance is available at http://www.cdc.gov/flu/weekly/fluactivitysurv.htm.

This dataset contains the following files for California influenza surveillance data: 1) Outpatient Influenza-like Illness Surveillance Data by Region and Influenza Season from volunteer sentinel providers; 2) Clinical Sentinel Laboratory Influenza and Other Respiratory Virus Surveillance Data by Region and Influenza Season from volunteer sentinel laboratories; and 3) Public Health Laboratory Influenza Respiratory Virus Surveillance Data by Region and Influenza Season from California public health laboratories. The Immunization Branch at the California Department of Public Health (CDPH) collects, compiles and analyzes information on influenza activity year-round in California and produces a weekly influenza surveillance report during October through May. The California influenza surveillance system is a collaborative effort between CDPH and its many partners at local health departments, public health and clinical laboratories, vital statistics offices, healthcare providers, clinics, emergency departments, and the Centers for Disease Control and Prevention (CDC). California data are also included in the CDC weekly influenza surveillance report, FluView, and help contribute to the national picture of Influenza activity in the United States. The information collected allows CDPH and CDC to: 1) find out when and where influenza activity is occurring; 2) track influenza-related illness; 3) determine what influenza viruses are circulating; 4) detect changes in influenza viruses; and 5) measure the impact influenza is having on hospitalizations and deaths.

This Dataset contains State and Year-wise total number of seasonal influenza (H1N1 Virus) cases and deaths.

Note: 1) Data for 2025 is as of 30 June. 2) Telangana State has reporting data separately since Nov, 2014 after separation from Andhra Pradesh.

BackgroundPoisson regression modelling has been widely used to estimate the disease burden attributable to influenza, though not without concerns that some of the excess burden could be due to other causes. This study aims to provide annual estimates of the mortality and hospitalization burden attributable to both seasonal influenza and the 2009 A/H1N1 pandemic influenza for Canada, and to discuss issues related to the reliability of these estimates.MethodsWeekly time-series for all-cause mortality and regression models were used to estimate the number of deaths in Canada attributable to influenza from September 1992 to December 2009. To assess their robustness, the annual estimates derived from different parameterizations of the regression model for all-cause mortality were compared. In addition, the association between the annual estimates for mortality and hospitalization by age group, underlying cause of death or primary reason for admission and discharge status is discussed.ResultsThe crude influenza-attributed mortality rate based on all-cause mortality and averaged over 17 influenza seasons prior to the 2009 A/H1N1 pandemic was 11.3 (95%CI, 10.5 - 12.1) deaths per 100 000 population per year, or an average of 3,500 (95%CI, 3,200 - 3,700) deaths per year attributable to seasonal influenza. The estimated annual rates ranged from undetectable at the ecological level to more than 6000 deaths per year over the three A/Sydney seasons. In comparison, we attributed an estimated 740 deaths (95%CI, 350–1500) to A(H1N1)pdm09. Annual estimates from different model parameterizations were strongly correlated, as were estimates for mortality and morbidity; the higher A(H1N1)pdm09 burden in younger age groups was the most notable exception.InterpretationWith the exception of some of the Serfling models, differences in the ecological estimates of the disease burden attributable to influenza were small in comparison to the variation in disease burden from one season to another.