Note: DPH is updating and streamlining the COVID-19 cases, deaths, and testing data. As of 6/27/2022, the data will be published in four tables instead of twelve. The COVID-19 Cases, Deaths, and Tests by Day dataset contains cases and test data by date of sample submission. The death data are by date of death. This dataset is updated daily and contains information back to the beginning of the pandemic. The data can be found at https://data.ct.gov/Health-and-Human-Services/COVID-19-Cases-Deaths-and-Tests-by-Day/g9vi-2ahj. The COVID-19 State Metrics dataset contains over 93 columns of data. This dataset is updated daily and currently contains information starting June 21, 2022 to the present. The data can be found at https://data.ct.gov/Health-and-Human-Services/COVID-19-State-Level-Data/qmgw-5kp6 . The COVID-19 County Metrics dataset contains 25 columns of data. This dataset is updated daily and currently contains information starting June 16, 2022 to the present. The data can be found at https://data.ct.gov/Health-and-Human-Services/COVID-19-County-Level-Data/ujiq-dy22 . The COVID-19 Town Metrics dataset contains 16 columns of data. This dataset is updated daily and currently contains information starting June 16, 2022 to the present. The data can be found at https://data.ct.gov/Health-and-Human-Services/COVID-19-Town-Level-Data/icxw-cada . To protect confidentiality, if a town has fewer than 5 cases or positive NAAT tests over the past 7 days, those data will be suppressed. COVID-19 cases and associated deaths that have been reported among Connecticut residents, broken down by race and ethnicity. All data in this report are preliminary; data for previous dates will be updated as new reports are received and data errors are corrected. Deaths reported to the either the Office of the Chief Medical Examiner (OCME) or Department of Public Health (DPH) are included in the COVID-19 update. The following data show the number of COVID-19 cases and associated deaths per 100,000 population by race and ethnicity. Crude rates represent the total cases or deaths per 100,000 people. Age-adjusted rates consider the age of the person at diagnosis or death when estimating the rate and use a standardized population to provide a fair comparison between population groups with different age distributions. Age-adjustment is important in Connecticut as the median age of among the non-Hispanic white population is 47 years, whereas it is 34 years among non-Hispanic blacks, and 29 years among Hispanics. Because most non-Hispanic white residents who died were over 75 years of age, the age-adjusted rates are lower than the unadjusted rates. In contrast, Hispanic residents who died tend to be younger than 75 years of age which results in higher age-adjusted rates. The population data used to calculate rates is based on the CT DPH population statistics for 2019, which is available online here: https://portal.ct.gov/DPH/Health-Information-Systems--Reporting/Population/Population-Statistics. Prior to 5/10/2021, the population estimates from 2018 were used. Rates are standardized to the 2000 US Millions Standard population (data available here: https://seer.cancer.gov/stdpopulations/). Standardization was done using 19 age groups (0, 1-4, 5-9, 10-14, ..., 80-84, 85 years and older). More information about direct standardization for age adjustment is available here: https://www.cdc.gov/nchs/data/statnt/statnt06rv.pdf Categories are mutually exclusive. The category “multiracial” includes people who answered ‘yes’ to more than one race category. Counts may not add up to total case counts as data on race and ethnicity may be missing. Age adjusted rates calculated only for groups with more than 20 deaths. Abbreviation: NH=Non-Hispanic. Data on Connecticut deaths were obtained from the Connecticut Deaths Registry maintained by the DPH Office of Vital Records. Cause of death was determined by a death certifier (e.g., physician, APRN, medical

This dataset is no longer being updated as of 5/11/2023. It is being retained on the Open Data Portal for its potential historical interest.

This table displays the number of COVID-19 deaths among Cambridge residents by race and ethnicity. The count reflects total deaths among Cambridge COVID-19 cases.

The rate column shows the rate of COVID-19 deaths among Cambridge residents by race and ethnicity. The rates in this chart were calculated by dividing the total number of deaths among Cambridge COVID-19 cases for each racial or ethnic category by the total number of Cambridge residents in that racial or ethnic category, and multiplying by 10,000. The rates are considered “crude rates” because they are not age-adjusted. Population data are from the U.S. Census Bureau’s 2014–2018 American Community Survey estimates and may differ from actual population counts.

Of note:

This chart reflects the time period of March 25 (first known Cambridge death) through present.

It is important to note that race and ethnicity data are collected and reported by multiple entities and may or may not reflect self-reporting by the individual case. The Cambridge Public Health Department (CPHD) is actively reaching out to cases to collect this information. Due to these efforts, race and ethnicity information have been confirmed for over 80% of Cambridge cases, as of June 2020.

Race/Ethnicity Category Definitions: “White” indicates “White, not of Hispanic origin.” “Black” indicates “Black, not of Hispanic origin.” “Hispanic” refers to a person having Hispanic origin. A person having Hispanic origin may be of any race. “Asian” indicates “Asian, not of Hispanic origin.” To protect individual privacy, a category is suppressed when it has one to four people. Categories with zero cases are reported as zero. "Other" indicates multiple races, another race that is not listed above, and cases who have reported nationality in lieu of a race category recognized by the US Census. Population data are from the U.S. Census Bureau’s 2014–2018 American Community Survey estimates and may differ from actual population counts. "Other" also includes a small number of people who identify as Native American or Native Hawaiian/Pacific islander. Because the count for Native Americans or Native Hawaiian/Pacific Islanders is currently < 5 people, these categories have been combined with “Other” to protect individual privacy.

To estimate county of residence of Filipinx healthcare workers who died of COVID-19, we retrieved data from the Kanlungan website during the month of December 2020.22 In deciding who to include on the website, the AF3IRM team that established the Kanlungan website set two standards in data collection. First, the team found at least one source explicitly stating that the fallen healthcare worker was of Philippine ancestry; this was mostly media articles or obituaries sharing the life stories of the deceased. In a few cases, the confirmation came directly from the deceased healthcare worker's family member who submitted a tribute. Second, the team required a minimum of two sources to identify and announce fallen healthcare workers. We retrieved 86 US tributes from Kanlungan, but only 81 of them had information on county of residence. In total, 45 US counties with at least one reported tribute to a Filipinx healthcare worker who died of COVID-19 were identified for analysis and will hereafter be referred to as “Kanlungan counties.” Mortality data by county, race, and ethnicity came from the National Center for Health Statistics (NCHS).24 Updated weekly, this dataset is based on vital statistics data for use in conducting public health surveillance in near real time to provide provisional mortality estimates based on data received and processed by a specified cutoff date, before data are finalized and publicly released.25 We used the data released on December 30, 2020, which included provisional COVID-19 death counts from February 1, 2020 to December 26, 2020—during the height of the pandemic and prior to COVID-19 vaccines being available—for counties with at least 100 total COVID-19 deaths. During this time period, 501 counties (15.9% of the total 3,142 counties in all 50 states and Washington DC)26 met this criterion. Data on COVID-19 deaths were available for six major racial/ethnic groups: Non-Hispanic White, Non-Hispanic Black, Non-Hispanic Native Hawaiian or Other Pacific Islander, Non-Hispanic American Indian or Alaska Native, Non-Hispanic Asian (hereafter referred to as Asian American), and Hispanic. People with more than one race, and those with unknown race were included in the “Other” category. NCHS suppressed county-level data by race and ethnicity if death counts are less than 10. In total, 133 US counties reported COVID-19 mortality data for Asian Americans. These data were used to calculate the percentage of all COVID-19 decedents in the county who were Asian American. We used data from the 2018 American Community Survey (ACS) five-year estimates, downloaded from the Integrated Public Use Microdata Series (IPUMS) to create county-level population demographic variables.27 IPUMS is publicly available, and the database integrates samples using ACS data from 2000 to the present using a high degree of precision.27 We applied survey weights to calculate the following variables at the county-level: median age among Asian Americans, average income to poverty ratio among Asian Americans, the percentage of the county population that is Filipinx, and the percentage of healthcare workers in the county who are Filipinx. Healthcare workers encompassed all healthcare practitioners, technical occupations, and healthcare service occupations, including nurse practitioners, physicians, surgeons, dentists, physical therapists, home health aides, personal care aides, and other medical technicians and healthcare support workers. County-level data were available for 107 out of the 133 counties (80.5%) that had NCHS data on the distribution of COVID-19 deaths among Asian Americans, and 96 counties (72.2%) with Asian American healthcare workforce data. The ACS 2018 five-year estimates were also the source of county-level percentage of the Asian American population (alone or in combination) who are Filipinx.8 In addition, the ACS provided county-level population counts26 to calculate population density (people per 1,000 people per square mile), estimated by dividing the total population by the county area, then dividing by 1,000 people. The county area was calculated in ArcGIS 10.7.1 using the county boundary shapefile and projected to Albers equal area conic (for counties in the US contiguous states), Hawai’i Albers Equal Area Conic (for Hawai’i counties), and Alaska Albers Equal Area Conic (for Alaska counties).20

Death rate has been age-adjusted by the 2000 U.S. standard populaton. All-cause mortality is an important measure of community health. All-cause mortality is heavily driven by the social determinants of health, with significant inequities observed by race and ethnicity and socioeconomic status. Black residents have consistently experienced the highest all-cause mortality rate compared to other racial and ethnic groups. During the COVID-19 pandemic, Latino residents also experienced a sharp increase in their all-cause mortality rate compared to White residents, demonstrating a reversal in the previously observed mortality advantage, in which Latino individuals historically had higher life expectancy and lower mortality than White individuals despite having lower socioeconomic status on average. The disproportionately high all-cause mortality rates observed among Black and Latino residents, especially since the onset of the COVID-19 pandemic, are due to differences in social and economic conditions and opportunities that unfairly place these groups at higher risk of developing and dying from a wide range of health conditions, including COVID-19.For more information about the Community Health Profiles Data Initiative, please see the initiative homepage.

City level open access data from 26 States and the Federal District and from the Brazilian Institute of Geography and Statistics (IBGE) [20], the Department of Informatics of Brazilian Public Health System – DATASUS, Ministry of Health, the Brazilian Agricultural Research Corporation (Embrapa) and from Brazil.io. Data from all 5,570 cities in Brazil were included in the analysis. COVID-19 data included cases and deaths reported between February 26th, 2020 and February 4th, 2021. The following outcomes were computed: a) days between the first case in Brazil until the first case in the city; b) days between the first case in the city until the day when 1,000 cases were reported; and c) days between the first death in city until the day when 50 deaths inhabitants were reported. Descriptive analyses were performed on the following: proportion of cities reaching 1,000 cases; number of cases at three, six, nine and 12 months after first case; cities reporting at least one COVID-19 related death; number of COVID-19 related deaths at three, six, nine and 12 months after first death in the country. All incidence data is adjusted for 100,000 inhabitants.The following covariates were included: a) geographic region where the city is located (Midwest, North, Northeast, Southeast and South), metropolitan city (no/yes) and urban or rural; b) social and environmental city characteristics [total area (Km2), urban area (Km2), population size (inhabitants), population living within urban area (inhabitants), population older than 60 years (%), indigenous population (%), black population (%), illiterate older than 25 years (%) and city in extreme poverty (no/yes)]; c) housing conditions [household with density >2 per dormitory (%), household with garbage collection (%), household connected to the water supply system (%) and household connected to the sewer system (%)]; d) job characteristics [commerce (%) and informal workers (%)]; e) socioeconomic and inequalities characteristics [GINI index; income per capita; poor or extremely poor (%) and households in informal urban settlements (%)]; f) health services access and coverage [number of National Public Health System (SUS) physicians per inhabitants (100,000 inhabitants), number of SUS nurses per inhabitants (100,000 inhabitants), number of intensive care units or ICU per inhabitants (100,000 inhabitants). All health services access and coverage variables were standardized using z-scores, combined into one single variable categorized into tertiles.

BackgroundThe COVID-19 pandemic has significantly impacted global health, with diverse factors influencing the risk of death among reported cases. This study mainly analyzes the main characteristics that have contributed to the increase or decrease in the risk of death among Severe Acute Respiratory Syndrome (SARS) cases classified as COVID-19 reported in southeast Brazil from 2020 to 2023.MethodsThis cohort study utilized COVID-19 notification data from the Sistema de Vigilância Epidemiológica (SIVEP) information system in the southeast region of Brazil from 2020 to 2023. Data included demographics, comorbidities, vaccination status, residence area, and survival outcomes. Classical Cox, Cox mixed effects, Prentice, Williams & Peterson (PWP), and PWP fragility models were used to assess the risk of dying over time.ResultsAcross 987,534 cases, 956,961 hospitalizations, and 330,343 deaths were recorded over the period. Mortality peaked in 2021. The elderly, males, black individuals, lower-educated, and urban residents faced elevated risks. Vaccination reduced death risk by around 20% and 13% in 2021 and 2022, respectively. Hospitalized individuals had lower death risks, while comorbidities increased risks by 20–26%.ConclusionThe study identified demographic and comorbidity factors influencing COVID-19 mortality. Rio de Janeiro exhibited the highest risk, while São Paulo had the lowest. Vaccination significantly reduces death risk. Findings contribute to understanding regional mortality variations and guide public health policies, emphasizing the importance of targeted interventions for vulnerable groups.

SARS-CoV-2 has caused symptomatic COVID-19 and widespread death across the globe. We sought to determine genetic variants contributing to COVID-19 susceptibility and hospitalization in a large biobank linked to a national United States health system. We identified 19,168 (3.7%) lab-confirmed COVID-19 cases among Million Veteran Program participants between March 1, 2020, and February 2, 2021, including 11,778 Whites, 4,893 Blacks, and 2,497 Hispanics. A multi-population genome-wide association study (GWAS) for COVID-19 outcomes identified four independent genetic variants (rs8176719, rs73062389, rs60870724, and rs73910904) contributing to COVID-19 positivity, including one novel locus found exclusively among Hispanics. We replicated eight of nine previously reported genetic associations at an alpha of 0.05 in at least one population-specific or the multi-population meta-analysis for one of the four MVP COVID-19 outcomes. We used rs8176719 and three additional variants to accurately infer ABO blood types. We found that A, AB, and B blood types were associated with testing positive for COVID-19 compared with O blood type with the highest risk for the A blood group. We did not observe any genome-wide significant associations for COVID-19 severity outcomes among those testing positive. Our study replicates prior GWAS findings associated with testing positive for COVID-19 among mostly White samples and extends findings at three loci to Black and Hispanic individuals. We also report a new locus among Hispanics requiring further investigation. These findings may aid in the identification of novel therapeutic agents to decrease the morbidity and mortality of COVID-19 across all major ancestral populations.

IntroductionCOVID-19 booster vaccines are highly effective at reducing severe illness and death from COVID-19. Research is needed to identify whether racial and ethnic disparities observed for the primary series of the COVID-19 vaccines persist for booster vaccinations and how those disparities may vary by other characteristics. We aimed to measure racial and ethnic differences in booster vaccine receipt among U.S. Medicare beneficiaries and characterize potential variation by demographic characteristics.MethodsWe conducted a cohort study using CVS Health and Walgreens pharmacy data linked to Medicare claims. We included community-dwelling Medicare beneficiaries aged ≥66 years who received two mRNA vaccine doses (BNT162b2 and mRNA-1273) as of 8/1/2021. We followed beneficiaries from 8/1/2021 until booster vaccine receipt, death, Medicare disenrollment, or end of follow-up (12/31/2021). Adjusted Poisson regression was used to estimate rate ratios (RRs) and 95% confidence intervals (CIs) comparing vaccine uptake between groups.ResultsWe identified 11,339,103 eligible beneficiaries (mean age 76 years, 60% female, 78% White). Overall, 67% received a booster vaccine (White = 68.5%; Asian = 67.0%; Black = 57.0%; Hispanic = 53.3%). Compared to White individuals, Black (RR = 0.78 [95%CI = 0.78–0.78]) and Hispanic individuals (RR = 0.72 [95% = CI 0.72–0.72]) had lower rates of booster vaccination. Disparities varied by geographic region, urbanicity, and Medicare plan/Medicaid eligibility. The relative magnitude of disparities was lesser in areas where vaccine uptake was lower in White individuals.DiscussionRacial and ethnic disparities in COVID-19 vaccination have persisted for booster vaccines. These findings highlight that interventions to improve vaccine uptake should be designed at the intersection of race and ethnicity and geographic location.

Abstract INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 has infected more than 9,834,513 Brazilians up to February 2021. Knowledge of risk factors of coronavirus disease among Brazilians remains scarce, especially in the adult population. This study verified the risk factors for intensive care unit admission and mortality for coronavirus disease among 20-59-year-old Brazilians. METHODS: A Brazilian database on respiratory illness was analyzed on October 9, 2020, to gather data on age, sex, ethnicity, education, housing area, and comorbidities (cardiovascular disease, diabetes, and obesity). Multivariate logistic regression analysis was performed to identify the risk factors for coronavirus disease. RESULTS: Overall, 1,048,575 persons were tested for coronavirus disease; among them, 43,662 were admitted to the intensive care unit, and 34,704 patients died. Male sex (odds ratio=1.235 and 1.193), obesity (odds ratio=1.941 and 1.889), living in rural areas (odds ratio=0.855 and 1.337), and peri-urban areas (odds ratio=1.253 and 1.577) were predictors of intensive care unit admission and mortality, respectively. Cardiovascular disease (odds ratio=1.552) was a risk factor for intensive care unit admission. Indigenous people had reduced chances (odds ratio=0.724) for intensive care unit admission, and black, mixed, East Asian, and indigenous ethnicity (odds ratio=1.756, 1.564, 1.679, and 1.613, respectively) were risk factors for mortality. CONCLUSIONS: Risk factors for intensive care unit admission and mortality among adult Brazilians were higher in men, obese individuals, and non-urban areas. Obesity was the strongest risk factor for intensive care unit admission and mortality.

Logistic regression models for mortality.

Crude and adjusted hazard ratio of the transitioning between individual’s conditions with COVID-19 (hospitalization and death) according to the predictors (southeast of Brazil).

COVID-19 mortality rates increase rapidly with age, are higher among men than women, and vary across racial/ethnic groups, but this is also true for other natural causes of death. Prior research on COVID-19 mortality rates and racial/ethnic disparities in those rates has not considered to what extent disparities reflect COVID-19-specific factors, versus preexisting health differences. This study examines both questions. We study the COVID-19-related increase in mortality risk and racial/ethnic disparities in COVID-19 mortality, and how both vary with age, gender, and time period. We use a novel measure validated in prior work, the COVID Excess Mortality Percentage (CEMP), defined as the COVID-19 mortality rate (Covid-MR), divided by the non-COVID natural mortality rate during the same time period (non-Covid NMR), converted to a percentage. The CEMP denominator uses Non-COVID NMR to adjust COVID-19 mortality risk for underlying population health. The CEMP measure generates insights which differ from those using two common measures–the COVID-MR and the all-cause excess mortality rate. By studying both CEMP and COVID-MRMR, we can separate the effects of background health from Covid-specific factors affecting COVID-19 mortality. We study how CEMP and COVID-MR vary by age, gender, race/ethnicity, and time period, using data on all adult decedents from natural causes in Indiana and Wisconsin over April 2020-June 2022 and Illinois over April 2020-December 2021. CEMP levels for racial and ethnic minority groups can be very high relative to White levels, especially for Hispanics in 2020 and the first-half of 2021. For example, during 2020, CEMP for Hispanics aged 18–59 was 68.9% versus 7.2% for non-Hispanic Whites; a ratio of 9.57:1. CEMP disparities are substantial but less extreme for other demographic groups. Disparities were generally lower after age 60 and declined over our sample period. Differences in socio-economic status and education explain only a small part of these disparities.