The number of deaths registered in England and Wales due to and involving coronavirus (COVID-19). Breakdowns include age, sex, region, local authority, Middle-layer Super Output Area (MSOA), indices of deprivation and place of death. Includes age-specific and age-standardised mortality rates.

Pre-existing conditions of people who died due to COVID-19, broken down by country, broad age group, and place of death occurrence, usual residents of England and Wales.

Due to changes in the collection and availability of data on COVID-19 this page will no longer be updated. The webpage will no longer be available as of 11 May 2023. On-going, reliable sources of data for COVID-19 are available via the COVID-19 dashboard, Office for National Statistics, and the UKHSA This page provides a weekly summary of data on deaths related to COVID-19 published by NHS England and the Office for National Statistics. More frequent reporting on COVID-19 deaths is now available here, alongside data on cases, hospitalisations, and vaccinations. This update contains data on deaths related to COVID-19 from: NHS England COVID-19 Daily Deaths - last updated on 28 June 2022 with data up to and including 27 June 2022. ONS weekly deaths by Local Authority - last updated on 16 August 2022 with data up to and including 05 August 2022. Summary notes about each these sources are provided at the end of this document. Note on interpreting deaths data: statistics from the available sources differ in definition, timing and completeness. It is important to understand these differences when interpreting the data or comparing between sources. Weekly Key Points An additional 24 deaths in London hospitals of patients who had tested positive for COVID-19 and an additional 5 where COVID-19 was mentioned on the death certificate were announced in the week ending 27 June 2022. This compares with 40 and 3 for the previous week. A total of 306 deaths in hospitals of patients who had tested positive for COVID-19 and 27 where COVID-19 was mentioned on the death certificate were announced for England as whole. This compares with 301 and 26 for the previous week. The total number of COVID-19 deaths reported in London hospitals of patients who had tested positive for COVID-19 is now 19,102. The total number of deaths in London hospitals where COVID-19 was mentioned on the death certificate is now 1,590. This compares to figures of 119,237 and 8,197 for English hospitals as a whole. Due to the delay between death occurrence and reporting, the estimated number of deaths to this point will be revised upwards over coming days These figures do not include deaths that occurred outside of hospitals. Data from ONS has indicated that the majority (79%) of COVID-19 deaths in London have taken place in hospitals. Recently announced deaths in Hospitals 21 June 22 June 23 June 24 June 25 June 26 June 27 June London No positive test 0 0 1 4 0 0 0 London Positive test 3 7 2 10 0 0 2 Rest of England No positive test 2 6 4 4 0 0 6 Rest of England Positive test 47 49 41 58 6 0 81 16 May 23 May 30 May 06 June 13 June 20 June 27 June London No positive test 14 3 4 0 4 3 5 London Positive test 45 34 55 20 62 40 24 Rest of England No positive test 41 58 33 23 47 23 22 Rest of England Positive test 456 375 266 218 254 261 282 Deaths by date of occurrence 21 June 22 June 23 June 24 June 25 June 26 June 27 June London 20,683 20,686 20,690 20,691 20,692 20,692 20,692 Rest of England 106,604 106,635 106,679 106,697 106,713 106,733 106,742 Interpreting the data The data published by NHS England are incomplete due to: delays in the occurrence and subsequent reporting of deaths deaths occurring outside of hospitals not being included The total deaths reported up to a given point are therefore less than the actual number that have occurred by the same point. Delays in reporting NHS provide the following guidance regarding the delay between occurrence and reporting of deaths: Confirmation of COVID-19 diagnosis, death notification and reporting in central figures can take up to several days and the hospitals providing the data are under significant operational pressure. This means that the totals reported at 5pm on each day may not include all deaths that occurred on that day or on recent prior days. The data published by NHS England for reporting periods from April 1st onward includes both date of occurrence and date of reporting and so it is possible to illustrate the distribution of these reporting delays. This data shows that approximately 10% of COVID-19 deaths occurring in London hospitals are included in the reporting period ending on the same day, and that approximately two-thirds of deaths were reported by two days after the date of occurrence. Deaths outside of hospitals The data published by NHS England does not include deaths that occur outside of hospitals, i.e. those in homes, hospices, and care homes. ONS have published data for deaths by place of occurrence. This shows that, up to 05 August, 79% of deaths in London recorded as involving COVID-19 occurred in hospitals (this compares with 44% for all causes of death). This would suggest that the NHS England data may underestimate overall deaths from COVID-19 by around 20%. Comparison of data sources Note on data sources NHS England provides numbers of patients who have died in hospitals in England and had tested positive for COVID-19, and from 25 April, the number of patients where COVID-19 is mentioned on the death certificate and no positive COVID-19 test result was received. Figures are updated each day at 2pm with deaths reported up to 5pm the previous day. There is a delay between the occurrence of a death to it being captured in the daily reporting. The data can be presented both as reported deaths by day and death occurrences by day. Reported occurrences for recent days should be considered incomplete as likely to be revised upwards as more data becomes available. The location of a death reflects the location of the hospital in which it occurred. Source: NHS England COVID-19 Daily Deaths The Office for National Statistics publishes deaths for England and Wales by the week in which they were registered. Due to the delay between the occurrence of a death and its registration, many deaths that occur in a given week will appear in the data for a subsequent week. For 2018, ONS estimated that 74% of deaths were registered within seven days. Additional delays in registration can occur over public holidays, with significant changes in numbers being observable over Easter and Christmas. The location of a death reflects the usual residence of the deceased. There are some differences in total numbers reported for different geographical levels. The figures published at the local authority level have been used in this analysis. The data is updated each Tuesday at 9.30am with data for the week ending eleven days prior. For the 2020 series, ONS has included the number of deaths where coronavirus (COVID-19) was mentioned on the death certificate. This data includes deaths for all places of occurrence. The ONS started publishing deaths in care homes notified to the Care Quality Commission on 28th April for local authorities in England by date of notification. This data includes an additional week of data compared to the main ONS publication. Source: Deaths registered weekly in England and Wales, provisional, Death registrations and occurrences by local authority, Deaths in care homes notified to the Care Quality Commission, report

Provisional counts of the number of deaths and age-standardised mortality rates involving the coronavirus (COVID-19), by occupational groups, for deaths registered between 9 March and 28 December 2020 in England and Wales. Figures are provided for males and females.

This mapping tool enables you to see how COVID-19 deaths in your area may relate to factors in the local population, which research has shown are associated with COVID-19 mortality. It maps COVID-19 deaths rates for small areas of London (known as MSOAs) and enables you to compare these to a number of other factors including the Index of Multiple Deprivation, the age and ethnicity of the local population, extent of pre-existing health conditions in the local population, and occupational data. Research has shown that the mortality risk from COVID-19 is higher for people of older age groups, for men, for people with pre-existing health conditions, and for people from BAME backgrounds. London boroughs had some of the highest mortality rates from COVID-19 based on data to April 17th 2020, based on data from the Office for National Statistics (ONS). Analysis from the ONS has also shown how mortality is also related to socio-economic issues such as occupations classified ‘at risk’ and area deprivation. There is much about COVID-19-related mortality that is still not fully understood, including the intersection between the different factors e.g. relationship between BAME groups and occupation. On their own, none of these individual factors correlate strongly with deaths for these small areas. This is most likely because the most relevant factors will vary from area to area. In some cases it may relate to the age of the population, in others it may relate to the prevalence of underlying health conditions, area deprivation or the proportion of the population working in ‘at risk occupations’, and in some cases a combination of these or none of them. Further descriptive analysis of the factors in this tool can be found here: https://data.london.gov.uk/dataset/covid-19--socio-economic-risk-factors-briefing

United Kingdom recorded 225324 Coronavirus Deaths since the epidemic began, according to the World Health Organization (WHO). In addition, United Kingdom reported 24603076 Coronavirus Cases. This dataset includes a chart with historical data for the United Kingdom Coronavirus Deaths.

NHS UK - COVID-19 Daily Deaths

This section contains information on deaths of patients who have died in hospitals in England and had tested positive for COVID-19 at time of death. All deaths are recorded against the date of death rather than the date the deaths were announced. Interpretation of the figures should take into account the fact that totals by date of death, particularly for most recent days, are likely to be updated in future releases. For example as deaths are confirmed as testing positive for COVID-19, as more post-mortem tests are processed and data from them are validated. Any changes are made clear in the daily files.

These figures do not include deaths outside hospital, such as those in care homes. This approach makes it possible to compile deaths data on a daily basis using up to date figures.

Dataset Content

These figures will be updated at 2pm each day and include confirmed cases reported at 5pm the previous day. Confirmation of COVID-19 diagnosis, death notification and reporting in central figures can take up to several days and the hospitals providing the data are under significant operational pressure. This means that the totals reported at 5pm on each day may not include all deaths that occurred on that day or on recent prior days.

The original dataset is sourced directly from the NHS source site, this original dataset is then cleaned and converted to a csv format available for inclusion into a Kaggle notebook.

There are 3 files considered within the data :- 1. Fatalities_by_age_uk 2.Fatalities_by_region_uk 3.Fatalities_by_trust_uk

Data runs from March 1st up to the current day. Any discrepancies will be outlined. The first is cumulative for any previous days leading up to of relevance. The following days are not cumulative and represent the updated value for the date under consideration.

A start kernel is provided to demonstrate using the dataset.

Citations

This dataset is sourced from the NHS statistical work areas:- https://www.england.nhs.uk/statistics/statistical-work-areas/

This dataset has been sourced and provided to aid in the following competition:- https://www.kaggle.com/c/covid19-global-forecasting-week-4

COVID-19Plots and analysis relating to the coronavirus pandemic. Includes five sets of plots and associated R code to generate them.1) HeatmapsUpdated every few days - heatmaps of COVID-19 case and death trajectories for Local Authorities (or equivalent) in England, Wales, Scotland, Ireland and Germany.2) All cause mortalityUpdated on Tuesday (for England & Wales), Wednesday (for Scotland) and Friday (for Northern Ireland) - analysis and plots of weekly all-cause deaths in 2020 compared to previous years by country, age, sex and region. Also a set of international comparisons using data from mortality.org3) ExposuresNo longer updated - mapping of potential COVID-19 mortality exposure at local levels (LSOAs) in England based on the age-sex structure of the population and levels of poor health.There is also a Shiny app which creates slightly lower resolution versions of the same plots online, which you can find here: https://victimofmaths.shinyapps.io/covidmapper/, on GitHub https://github.com/VictimOfMaths/COVIDmapper and uploaded to this record4) Index of Multiple Deprivation No longer updated - preliminary analysis of the inequality impacts of COVID-19 based on Local Authority level cases and levels of deprivation. 5) Socioeconomic inequalities. No longer updated (unless ONS release more data) - Analysis of published ONS figures of COVID-19 and other cause mortality in 2020 compared to previous years by deprivation decile.Latest versions of plots and associated analysis can be found on Twitter: https://twitter.com/victimofmathsThis work is described in more detail on the UK Data Service Impact and Innovation Lab blog: https://blog.ukdataservice.ac.uk/visualising-high-risk-areas-for-covid-19-mortality/Adapted from data from the Office for National Statistics licensed under the Open Government Licence v.1.0.http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/

Dataset description

Daily official UK Covid data. The data is available per country (England, Scotland, Wales and Northern Ireland) and for different regions in England. The different regions are split into two different files as part of the data is directly gathered by the NHS (National Health Service). The files that contain the word 'nhsregion' in their name, include data related to hospitals only, such as number of admissions or number of people in respirators. The files containing the word 'region' in their name, include the rest of the data, such as number of cases, number of vaccinated people or number of tests performed per day. The next paragraphs describe the columns for the different file types.

Region files

Files related to regions (word 'region' included in the file name) have the following columns: - "date": date in YYYY-MM-DD format - "area type": type of area covered in the file (region or nation) - "area name": name of area covered in the file (region or nation name) - "daily cases": new cases on a given date - "cum cases": cumulative cases - "new deaths 28days": new deaths within 28 days of a positive test - "cum deaths 28days": cumulative deaths within 28 days of a positive test - "new deaths_60days": new deaths within 60 days of a positive test - "cum deaths 60days": cumulative deaths within 60 days of a positive test - "new_first_episode": new first episodes by date - "cum_first_episode": cumulative first episodes by date - "new_reinfections": new reinfections by specimen data - "cum_reinfections": cumualtive reinfections by specimen data - "new_virus_test": new virus tests by date - "cum_virus_test": cumulative virus tests by date - "new_pcr_test": new PCR tests by date - "cum_pcr_test": cumulative PCR tests by date - "new_lfd_test": new LFD tests by date - "cum_lfd_test": cumulative LFD tests by date - "test_roll_pos_pct": percentage of unique case positivity by date rolling sum - "test_roll_people": unique people tested by date rolling sum - "new first dose": new people vaccinated with a first dose - "cum first dose": cumulative people vaccinated with a first dose - "new second dose": new people vaccinated with a first dose - "cum second dose": cumulative people vaccinated with a first dose - "new third dose": new people vaccinated with a booster or third dose - "cum third dose": cumulative people vaccinated with a booster or third dose

Country files

Files related to countries (England, Northern Ireland, Scotland and Wales) have the above columns and also: - "new admissions": new admissions, - "cum admissions": cumulative admissions, - "hospital cases": patients in hospitals, - "ventilator beds": COVID occupied mechanical ventilator beds - "trans_rate_min": minimum transmission rate (R) - "trans_rate_max": maximum transmission rate (R) - "trans_growth_min": transmission rate growth min - "trans_growth_max": transmission rate growth max

NHS Region files

Files related to nhsregion (word 'nhsregion' included in the file name) have the following columns: - "new admissions": new admissions, - "cum admissions": cumulative admissions, - "hospital cases": patients in hospitals, - "ventilator beds": COVID occupied mechanical ventilator beds - "trans_rate_min": minimum transmission rate (R) - "trans_rate_max": maximum transmission rate (R) - "trans_growth_min": transmission rate growth min - "trans_growth_max": transmission rate growth max

It's worth noting that the dataset hasn't been cleaned and it needs cleaning. Also, different files have different null columns. This isn't an error in the dataset but the way different countries and regions report the data.

Context

• Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus SARS-CoV2.
• Person to person transmission occurs via several different modes, mainly when people are in close proximity to one another through respiratory droplets.
• Mitigations by various countries have been put into place to limit the spread of this virus.

Content

• ConfirmedCasesByDateReported.csv
• ConfirmedCasesBySpecimenDate.csv
• Deaths.csv
• PatientNewAdmissions.csv
• PatientsInHospital.csv
• PatientsMVBeds.csv
• PCRTesting.csv
• Vaccinations.csv
• VaccinationsDaily.csv

Acknowledgements and Collection Methodology

Data downloaded from https://coronavirus.data.gov.uk

Version

• Version 11 - 25 - Various Files Updated.
• Version 10 - Added VaccinationsDaily File, data upto and including the 20th Jan 2021.
• Version 9 - Updated Deaths file, data upto and including the 20th Jan 2021.
• Version 8 - Updated ConfirmedCasesByDateReported and ConfirmedCasesBySpecimenDate files, data upto and including the 17th to 19th Jan 2021 respectively.
• Version 7 - Updated PatientNewAdmissions, PatientsInHospital and PatientsMVBeds files, data upto and including the 12th to 15th Jan 2020 depending on file.
• Version 6 - Updated PCR Testing file, data upto and including the 14th Jan 2021.
• Version 4 - Updated Vaccinations file, data upto and including the 3rd Jan 2021.
• Version 3 - Updated to include data unto and including the 28th December 2020. Additionally added data on the progress of Vaccinations.
• Version 2 - Updated to include data unto and including the 3rd November 2020.

11th January 2020 Change to vaccination data made available by UK gov - now just cumulative number of vaccines delivered are available for both first and second doses. For the devolved nations the cumulative totals are available for the dates from when given, however for the UK as a whole the total doses given is just on the last date of the index, regardless of when those vaccines were given.

4th January 2020 VACCINATION DATA ADDED - New and Cumulative First Dose Vaccination Data added to UK_National_Total_COVID_Dataset.csv and UK_Devolved_Nations_COVID_Dataset.csv

2nd December 2020:

NEW population, land area and population density data added in file NEW_Official_Population_Data_ONS_mid-2019.csv. This data is scraped from the Office for National Statistics and covers the UK, devolved UK nations, regions and local authorities (boroughs).

20th November 2020:

With European governments struggling with a 'second-wave' of rising cases, hospitalisations and deaths resulting from the SARS-CoV-2 virus (COVID-19), I wanted to make a comparative analysis between the data coming out of major European nations since the start of the pandemic.

I started by creating a Sweden COVID-19 dataset and now I'm looking at my own country, the United Kingdom.

The data comes from https://coronavirus.data.gov.uk/ and I used the Developer's Guide to scrape the data, so it was a fairly simple process. The notebook that scapes the data is public and can be found here. Further information about data collection methodologies and definitions can be found here.

The data includes the overall numbers for the UK as a whole, the numbers for each of the devolved UK nations (Eng, Sco, Wal & NI), English Regions and Upper Tier Local Authorities (UTLA) for all of the UK (what we call Boroughs). I have also included a small table with the populations of the 4 devolved UK nations, used to calculate the death rates per 100,000 population.

As I've said for before - I am not an Epidemiologist, Sociologist or even a Data Scientist. I am actually a Mechanical Engineer! The objective here is to improve my data science skills and maybe provide some useful data to the wider community.

Any questions, comments or suggestions are most welcome! I am open to requests and collaborations! Stay Safe!

This dataset shows the provisional COVID-19 Death registrations and occurrences by local authority and health board in England and Wales. This dataset has been prepared by Office for National Statistics.

Provisional deaths registration data for single year of age and average age of death (median and mean) of persons whose death involved coronavirus (COVID-19), England and Wales. Includes deaths due to COVID-19 and breakdowns by sex.

Context

COVID-19 is a Pandemic which was spread worldwide in the early months of 2020, Which has had a major impact on the United Kingdom. As the UK has recently carried out wide spread vaccination and ended Lockdown I am providing the recent COVID-19 figures.

Content

Several Datasets are provided, focusing on Deaths, Cases, Hospitalisation and Vaccination. Files often protray the same information but from a different reference point. For example for Deaths there is one displaying figures from people who died using there positive date as a reference point, whereas the other is using the date of death.

Acknowledgements

These datasets was scrapped off the UK Gov website in regards to COVID-19. For those looking to build a more complex project using a constant data flow, they do provide an API which may assist.

Inspiration

Possible area to explore are: What was the Impact of Vaccines on the COVID-19 Pandemic? What was the Impact of a Lockdown on the COVID-19 Pandemic? Which Nation managed the spread of COVID-19 the best?

Licence

Open Government Licence V3.0

The number of deaths registered in Leicester including deaths involving coronavirus (Covid-19).The data will be updated weekly.

The Public Health Research Database (PHRD) is a linked asset which currently includes Census 2011 data; Mortality Data; Hospital Episode Statistics (HES); GP Extraction Service (GPES) Data for Pandemic Planning and Research data. Researchers may apply for these datasets individually or any combination of the current 4 datasets.

The purpose of this dataset is to enable analysis of deaths involving COVID-19 by multiple factors such as ethnicity, religion, disability and known comorbidities as well as age, sex, socioeconomic and marital status at subnational levels. 2011 Census data for usual residents of England and Wales, who were not known to have died by 1 January 2020, linked to death registrations for deaths registered between 1 January 2020 and 8 March 2021 on NHS number. The data exclude individuals who entered the UK in the year before the Census took place (due to their high propensity to have left the UK prior to the study period), and those over 100 years of age at the time of the Census, even if their death was not linked. The dataset contains all individuals who died (any cause) during the study period, and a 5% simple random sample of those still alive at the end of the study period. For usual residents of England, the dataset also contains comorbidity flags derived from linked Hospital Episode Statistics data from April 2017 to December 2019 and GP Extraction Service Data from 2015-2019.

The number of deaths, based on a 7-day rolling sum of deaths recorded where a diagnosis of Covid-19 within 28 days of the date of death has been recorded.Please note automatic updates to this dataset was discontinued on 3rd July 2023.

Based on a comparison of coronavirus deaths in 210 countries relative to their population, Peru had the most losses to COVID-19 up until July 13, 2022. As of the same date, the virus had infected over 557.8 million people worldwide, and the number of deaths had totaled more than 6.3 million. Note, however, that COVID-19 test rates can vary per country. Additionally, big differences show up between countries when combining the number of deaths against confirmed COVID-19 cases. The source seemingly does not differentiate between "the Wuhan strain" (2019-nCOV) of COVID-19, "the Kent mutation" (B.1.1.7) that appeared in the UK in late 2020, the 2021 Delta variant (B.1.617.2) from India or the Omicron variant (B.1.1.529) from South Africa.

The difficulties of death figures

This table aims to provide a complete picture on the topic, but it very much relies on data that has become more difficult to compare. As the coronavirus pandemic developed across the world, countries already used different methods to count fatalities, and they sometimes changed them during the course of the pandemic. On April 16, for example, the Chinese city of Wuhan added a 50 percent increase in their death figures to account for community deaths. These deaths occurred outside of hospitals and went unaccounted for so far. The state of New York did something similar two days before, revising their figures with 3,700 new deaths as they started to include “assumed” coronavirus victims. The United Kingdom started counting deaths in care homes and private households on April 29, adjusting their number with about 5,000 new deaths (which were corrected lowered again by the same amount on August 18). This makes an already difficult comparison even more difficult. Belgium, for example, counts suspected coronavirus deaths in their figures, whereas other countries have not done that (yet). This means two things. First, it could have a big impact on both current as well as future figures. On April 16 already, UK health experts stated that if their numbers were corrected for community deaths like in Wuhan, the UK number would change from 205 to “above 300”. This is exactly what happened two weeks later. Second, it is difficult to pinpoint exactly which countries already have “revised” numbers (like Belgium, Wuhan or New York) and which ones do not. One work-around could be to look at (freely accessible) timelines that track the reported daily increase of deaths in certain countries. Several of these are available on our platform, such as for Belgium, Italy and Sweden. A sudden large increase might be an indicator that the domestic sources changed their methodology.

Where are these numbers coming from?

The numbers shown here were collected by Johns Hopkins University, a source that manually checks the data with domestic health authorities. For the majority of countries, this is from national authorities. In some cases, like China, the United States, Canada or Australia, city reports or other various state authorities were consulted. In this statistic, these separately reported numbers were put together. For more information or other freely accessible content, please visit our dedicated Facts and Figures page.

A List of UK Health Workers Who Have Died from COVID-19

Made machine-readable by hand from data from the UK newspaper "The Guardian", in this article: "Doctors, nurses, porters, volunteers: the UK health workers who have died from Covid-19" https://www.theguardian.com/world/2020/apr/16/doctors-nurses-porters-volunteers-the-uk-health-workers-who-have-died-from-covid-19

The Guardian is continuing to update the list day-by-day, as the COVID-19 pandemic continues. I do not plan to update this dataset, assuming, since the data collection biases are unknown, that nobody else will find it very interesting. I am not a copyright lawyer and do not know if this data is protected copyright, and if so, in which parts of the world.

Caveat: Creating this dataset from a newspaper article required a lot of hand work. I've done my best, but there may be mistakes.

Columns: Name age institution city: I have filled this in myself; I am ignorant of UK geography and there may well be mistakes date_of_death possible_ppe_issue: mostly blank, but I have filled in "yes" where the article mentions a person who had doubts about the adequacy of PPE (personal protective equipment) MED_SPEC: I have attempted to fill in a medical specialty from the values used on the Eurostat web site for Physicians by Medical Specialty" and "Nursing and caring professionals" tables. The idea is to be able to calculate a fraction of affected individuals by specialty.

Estimates of the risk of hospital admission for coronavirus (COVID-19) and death involving COVID-19 by vaccination status, overall and by age group, using anonymised linked data from Census 2021. Experimental Statistics.

Outcome definitions

For this analysis, we define a death as involving COVID-19 if either of the ICD-10 codes U07.1 (COVID-19, virus identified) or U07.2 (COVID-19, virus not identified) is mentioned on the death certificate. Information on cause of death coding is available in the User Guide to Mortality Statistics. We use date of occurrance rather than date of registration to give the date of the death.

We define COVID-109 hospitalisation as an inpatient episode in Hospital Episode Statistics where the primary diagnosis was COVID-19, identified by the ICD-19 codes (COVID-19, virus identified) or U07.2 (COVID-19, virus not identified). Where an individual had experienced more than one COVID-19 hospitalisation, the earliest that occurred within the study period was used. We define the date of COVID-19 hospitalisation as the start of the hospital episode.

ICD-10 code

U07.1 :

COVID-19, virus identified

U07.2:

COVID-19, virus not identified

Vaccination status is defined by the dose and the time since the last dose received

Unvaccinated:

no vaccination to less than 21 days post first dose

First dose 21 days to 3 months:

more than or equal to 21 days post second dose to earliest of less than 91 days post first dose or less than 21 days post second dose

First dose 3+ months:

more than or equal to 91 days post first dose to less than 21 days post second dose

Second dose 21 days to 3 months:

more than or equal to 21 days post second dose to earliest of less than 91 days post second dose or less than 21 days post third dose

Second dose 3-6 months:

more than or equal to 91 days post second dose to earliest of less than 182 days post second dose or less than 21 days post third dose

Second dose 6+ months:

more than or equal to 182 days post second dose to less than 21 days post third dose

Third dose 21 days to 3 months:

more than or equal to 21 days post third dose to less than 91 days post third dose

Third dose 3+ months:

more than or equal to 91 days post third dose

Model adjustments

Three sets of model adjustments were used

Age adjusted:

age (as a natural spline)

Age, socio-demographics adjusted:

age (as a natural spline), plus socio-demographic characteristics (sex, region, ethnicity, religion, IMD decile, NSSEC category, highest qualification, English language proficiency, key worker status)

Fully adjusted:

age (as a natural spline), plus socio-demographic characteristics (sex, region, ethnicity, religion, IMD decile, NSSEC category, highest qualification, English language proficiency, key worker status), plus health-related characteristics (disability, self-reported health, care home residency, number of QCovid comorbidities (grouped), BMI category, frailty flag and hospitalisation within the last 21 days.

Age

Age in years is defined on the Census day 2021 (21 March 2021). Age is included in the model as a natural spline with boundary knots at the 10th and 90th centiles and internal knots at the 25th, 50th and 75th centiles. The positions of the knots are calculated separately for the overall model and for each age group for the stratified model.