United Kingdom UK: Incidence of Tuberculosis: per 100,000 People data was reported at 9.900 Ratio in 2016. This records a decrease from the previous number of 10.000 Ratio for 2015. United Kingdom UK: Incidence of Tuberculosis: per 100,000 People data is updated yearly, averaging 13.000 Ratio from Dec 2000 (Median) to 2016, with 17 observations. The data reached an all-time high of 15.000 Ratio in 2011 and a record low of 9.900 Ratio in 2016. United Kingdom UK: Incidence of Tuberculosis: per 100,000 People data remains active status in CEIC and is reported by World Bank. The data is categorized under Global Database’s United Kingdom – Table UK.World Bank.WDI: Health Statistics. Incidence of tuberculosis is the estimated number of new and relapse tuberculosis cases arising in a given year, expressed as the rate per 100,000 population. All forms of TB are included, including cases in people living with HIV. Estimates for all years are recalculated as new information becomes available and techniques are refined, so they may differ from those published previously.; ; World Health Organization, Global Tuberculosis Report.; Weighted average;

United Kingdom UK: Contraceptive Prevalence: Any Methods: % of Women Aged 15-49 data was reported at 84.000 % in 2009. This records an increase from the previous number of 82.000 % for 2008. United Kingdom UK: Contraceptive Prevalence: Any Methods: % of Women Aged 15-49 data is updated yearly, averaging 82.000 % from Dec 1976 (Median) to 2009, with 20 observations. The data reached an all-time high of 84.000 % in 2009 and a record low of 69.000 % in 1989. United Kingdom UK: Contraceptive Prevalence: Any Methods: % of Women Aged 15-49 data remains active status in CEIC and is reported by World Bank. The data is categorized under Global Database’s United Kingdom – Table UK.World Bank.WDI: Health Statistics. Contraceptive prevalence rate is the percentage of women who are practicing, or whose sexual partners are practicing, any form of contraception. It is usually measured for women ages 15-49 who are married or in union.; ; UNICEF's State of the World's Children and Childinfo, United Nations Population Division's World Contraceptive Use, household surveys including Demographic and Health Surveys and Multiple Indicator Cluster Surveys.; Weighted average; Contraceptive prevalence amongst women of reproductive age is an indicator of women's empowerment and is related to maternal health, HIV/AIDS, and gender equality.

IntroductionPeople living with HIV (PLWH) now have near-normal life-expectancy, but still experience stigma, and HIV status is treated as sensitive health information. When UK healthcare patient data is curated into anonymised datasets for research, HIV diagnostic codes are stripped out. As PLWH age, we must research how HIV affects conditions of ageing, but cannot do so in current NHS research datasets. We aimed to elicit views on HIV status being shared in NHS datasets, and identify appropriate safeguards.MethodsWe conducted three focus groups with a convenience sample of PLWH recruited through HIV charities, presenting information on data governance, data-sharing, patient privacy, law, and research areas envisaged for HIV and ageing. Each focus group involved two presentations, a question session, and facilitated breakout discussion groups. Discussions were audio-recorded, transcribed and analysed thematically.Results37 PLWH (age range 23-58y) took part. The overarching theme was around trust, both the loss of trust experienced by participants due to previous negative or discriminatory experiences, and the need to slowly build trust in data-sharing initiatives. Further themes showed that participants were supportive of data being used for research and health care improvements, but needed a guarantee that their privacy would be protected. A loss of trust in systems and organisations using the data, suspicion of data users’ agendas, and worry about increased discrimination and stigmatisation made them cautious about data sharing. To rebuild trust participants wanted to see transparent security protocols, accountability for following these, and communication about data flows and uses, as well as awareness training about HIV, and clear involvement of PLWH as full stakeholders on project teams and decision-making panels.ConclusionsPLWH were cautiously in favour of their data being shared for research into HIV, where this could be undertaken with high levels of security, and the close involvement of PLWH to set research agendas and avoid increased stigma.

Abstract copyright UK Data Service and data collection copyright owner.The Opinions and Lifestyle Survey (formerly known as the ONS Opinions Survey or Omnibus) is an omnibus survey that began in 1990, collecting data on a range of subjects commissioned by both the ONS internally and external clients (limited to other government departments, charities, non-profit organisations and academia).Data are collected from one individual aged 16 or over, selected from each sampled private household. Personal data include data on the individual, their family, address, household, income and education, plus responses and opinions on a variety of subjects within commissioned modules. The questionnaire collects timely data for research and policy analysis evaluation on the social impacts of recent topics of national importance, such as the coronavirus (COVID-19) pandemic and the cost of living, on individuals and households in Great Britain. From April 2018 to November 2019, the design of the OPN changed from face-to-face to a mixed-mode design (online first with telephone interviewing where necessary). Mixed-mode collection allows respondents to complete the survey more flexibly and provides a more cost-effective service for customers. In March 2020, the OPN was adapted to become a weekly survey used to collect data on the social impacts of the coronavirus (COVID-19) pandemic on the lives of people of Great Britain. These data are held in the Secure Access study, SN 8635, ONS Opinions and Lifestyle Survey, Covid-19 Module, 2020-2022: Secure Access. From August 2021, as coronavirus (COVID-19) restrictions were lifting across Great Britain, the OPN moved to fortnightly data collection, sampling around 5,000 households in each survey wave to ensure the survey remains sustainable. The OPN has since expanded to include questions on other topics of national importance, such as health and the cost of living. For more information about the survey and its methodology, see the ONS OPN Quality and Methodology Information webpage.Secure Access Opinions and Lifestyle Survey dataOther Secure Access OPN data cover modules run at various points from 1997-2019, on Census religion (SN 8078), cervical cancer screening (SN 8080), contact after separation (SN 8089), contraception (SN 8095), disability (SNs 8680 and 8096), general lifestyle (SN 8092), illness and activity (SN 8094), and non-resident parental contact (SN 8093). See Opinions and Lifestyle Survey: Secure Access for details. Main Topics:Each month's questionnaire consists of two elements: core questions, covering demographic information, are asked each month together with non-core questions that vary from month to month. The non-core questions for this month were: Tobacco consumption (Module 210): this module was asked on behalf of Customs and Excise to help them estimate the amount of tobacco consumed as cigarettes. Intention to stop smoking (Module 298): this module was asked on behalf of ASH, the anti-smoking lobby. They were interested in when smokers think they might stop smoking and whether they have used No Smoking Day to help them quit. The questions about No Smoking Day were also asked of ex-smokers. Internet access (Module 264): this module was asked on behalf of a number of government departments, but primarily the Office for National Statistics and the e-Envoy's Office (part of the Cabinet Office). Designed to monitor internet use, which is currently a high profile government policy. Human rights (Module 243): this module was asked on behalf of the Home Office and concerned an individual's rights to liberty in the UK. Area regeneration (Module 296): questions concerning people's perceptions of the area they live in, asked on behalf of the Department for Transport, Local Government and the Regions. Grandparents (Module 294): asked on behalf of the London School of Hygiene and Tropical Medicine and the ESRC, this module is in two parts. Part one looks at attitudes to being a grandparent and number of grandchildren; part two looks at the characteristics of up to four sets of grandchildren, including how often the respondent sees them and the ways in which they help one another. Non-resident parental contact (Module 299): these questions were asked on behalf of the Lord Chancellor's Department and are about children who live with only one of their birth parents. AIDS awareness (Module 300): this module was asked on behalf of the National AIDS Trust (NAT), who were interested in finding out how respondents perceive people infected with HIV or AIDS and how these people might be treated by society. Multi-stage stratified random sample Face-to-face interview

HIV (human immunodeficiency virus) is a virus that damages the cells in your immune system and weakens your ability to fight everyday infections and disease. AIDS (acquired immune deficiency syndrome) is the name used to describe a number of potentially life-threatening infections and illnesses that happen when your immune system has been severely damaged by the HIV virus. While AIDS cannot be transmitted from 1 person to another, the HIV virus can.Free and effective antiretroviral therapy (ART) in the UK has transformed HIV from a fatal infection into a chronic but manageable condition. People living with HIV in the UK can now expect to have a near normal life expectancy if diagnosed promptly and they adhere to treatment. In addition, those on treatment are unable to pass on HIV, even if having unprotected sex (undetectable=untransmissible [U=U]).Data reported in 2020 were impacted by the changes in how people accessed health services, and their reconfiguration during the COVID-19 pandemic, which also resulted in data reporting delays.In 2020, an estimated 97,740 (95% credible interval (95% Crl) 96,400 to 100,060) people were living with HIV in England and an estimated 4,660 in 2020 (95%CrI 3,640 to 6,980) were unaware of their infection.[1] The quality of care received by people living with HIV remained high. For the first time, the UNAIDS 95-95-95 targets[2] were met with 95% of all people diagnosed, 99% of those in care on treatment and 97% of those receiving treatment being virally suppressed in both the UK and England. This means that 91% of all people living with HIV and accessing care were virally suppressed in 2020, surpassing the 73% UNAIDS 90-90-90 substantial target as well as the 86% UNAIDS 95-95-95 substantial target.Overall, 98% (80,250 out of 82,061) of people living with HIV in England with a viral load reported in 2021 were virally suppressed; slightly higher than the proportion of viral suppression seen in both 2019 and 2020 (97%). The number of people living with HIV who were virally suppressed in 2021 (80,250) exceeded the total in both 2019 and 2020 (79,242 and 70,632, respectively).In 2021, 2,955 people were newly diagnosed with HIV in the UK (includes people previously diagnosed abroad), of whom 90% (2,692) were diagnosed in England. The number of all new HIV diagnoses in the UK, decreased by 0.2% from 2,961 in 2020 and a 33%decreasedl from 4,408 in 2019. For England, the equivalent figures were a 0.7% rise from 2,673 (2020) and a 33% fall from 4,017 (2019).

Disease progression in HIV-infected individuals varies greatly, and while the environmental and host factors influencing this variation have been widely investigated, the viral contribution to variation in set-point viral load, a predictor of disease progression, is less clear. Previous studies, using transmission-pairs and analysis of phylogenetic signal in small numbers of individuals, have produced a wide range of viral genetic effect estimates. Here we present a novel application of a population-scale method based in quantitative genetics to estimate the viral genetic effect on set-point viral load in the UK subtype B HIV-1 epidemic, based on a very large data set. Analyzing the initial viral load and associated pol sequence, both taken before anti-retroviral therapy, of 8,483 patients, we estimate the proportion of variance in viral load explained by viral genetic effects to be 5.7% (CI 2.8–8.6%). We also estimated the change in viral load over time due to selection on the virus and environmental effects to be a decline of 0.05 log10 copies/mL/year, in contrast to recent studies which suggested a reported small increase in viral load over the last 20 years might be due to evolutionary changes in the virus. Our results suggest that in the UK epidemic, subtype B has a small but significant viral genetic effect on viral load. By allowing the analysis of large sample sizes, we expect our approach to be applicable to the estimation of the genetic contribution to traits in many organisms.

The 1998 Kenya Demographic and Health Survey (KDHS) is a nationally representative survey of 7,881 women age 15-49 and 3,407 men age 15-54. The KDHS was implemented by the National Council for Population and Development (NCPD) and the Central Bureau of Statistics (CBS), with significant technical and logistical support provided by the Ministry of Health and various other governmental and nongovernmental organizations in Kenya. Macro International Inc. of Calverton, Maryland (U.S.A.) provided technical assistance throughout the course of the project in the context of the worldwide Demographic and Health Surveys (DHS) programme, while financial assistance was provided by the U.S. Agency for International Development (USAID/Nairobi) and the Department for International Development (DFID/U.K.). Data collection for the KDHS was conducted from February to July 1998. Like the previous KDHS surveys conducted in 1989 and 1993, the 1998 KDHS was designed to provide information on levels and trends in fertility, family planning knowledge and use, infant and child mortality, and other maternal and child health indicators. However, the 1998 KDHS went further to collect more in-depth data on knowledge and behaviours related to AIDS and other sexually transmitted diseases (STDs), detailed “calendar” data that allows estimation of contraceptive discontinuation rates, and information related to the practice of female circumcision. Further, unlike earlier surveys, the 1998 KDHS provides a national estimate of the level of maternal mortality (i.e. related to pregnancy and childbearing). The KDHS data are intended for use by programme managers and policymakers to evaluate and improve health and family planning programmes in Kenya. OBJECTIVES OF THE SURVEY The principal aim of the 1998 KDHS project is to provide up-to-date information on fertility and childhood mortality levels, nuptiality, fertility preferences, awareness and use of family planning methods, use of maternal and child health services, and knowledge and behaviours related to HIV/AIDS and other sexually-transmitted diseases. It was designed as a follow-on to the 1989 KDHS and 1993 KDHS, national-level surveys of similar size and scope. Ultimately, the 1998 KDHS project seeks to: Assess the overall demographic situation in Kenya; Assist in the evaluation of the population and reproductive health programmes in Kenya; Advance survey methodology; and Assist the NCPD to strengthen its capacity to conduct demographic and health surveys. The 1998 KDHS was specifically designed to: Provide data on the family planning and fertility behaviour of the Kenyan population, and to thereby enable the NCPD to evaluate and enhance the national family planning programme; Measure changes in fertility and contraceptive prevalence and at the same time study the factors which affect these changes, such as marriage patterns, desire for children, availability of contraception, breastfeeding habits, and important social and economic factors; Examine the basic indicators of maternal and child health in Kenya, including nutritional status, use of antenatal and maternity services, treatment of recent episodes of childhood illness, and use of immunisation services; Describe levels and patterns of knowledge and behaviour related to the prevention of AIDS and other sexually transmitted infection; Measure adult and maternal mortality at the national level; and Ascertain the extent and pattern of female circumcision in the country. MAIN RESULTS Fertility. The survey results demonstrate a continuation of the fertility transition in Kenya. Marriage. The age at which women and men first marry has risen slowly over the past 20 years. Fertility Preferences. Fifty-three percent of women and 46 percent of men in Kenya do not want to have any more children. Family Planning. Knowledge and use of family planning in Kenya has continued to rise over the last several years. Early Childhood Mortality. Results from the 1998 KDHS data make clear that childhood mortality conditions have worsened in the early-mid 1990s;Maternal Health. Utilisation of antenatal services is high in Kenya; in the three years before the survey, mothers received antenatal care for 92 percent of births (Note: These data do not speak to the quality of those antenatal services). Childhood Immunisation. The KDHS found that 65 percent of children age 12-23 months are fully vaccinated: this includes BCG and measles vaccine, and at least 3 doses of both DPT and polio vaccines. Infant Feeding. Almost all children (98 percent) are breastfed for some period of time; however, only 58 percent are breastfed within the first hour of life, and 86 percent within the first day after birth. Nutritional Status The results indicate that one-third of children in Kenya are stunted (i.e., too short for their age), a condition reflecting chronic malnutrition; and 1 in 16 children are wasted (i.e., very thin), a problem indicating acute or short-term food deficit. Knowledge, Attitudes and Behaviour regarding HIV/AIDS and Other Sexually Transmitted Infections. As a measure of the increasing toll taken by AIDS on Kenyan society, the percentage of respondents who reported “personally knowing someone who has AIDS or has died from AIDS” has risen from about 40 percent of men and women in the 1993 KDHS to nearly three-quarters of men and women in 1998. Female Circumcision. The results indicate that 38 percent of women age 15-49 in Kenya have been circumcised. The prevalence of FC has however declined significantly over the last 2 decades from about one-half of women in the oldest age cohorts to about one-quarter of women in the youngest cohorts (including daughters age 15+).

A majority of individuals infected with human immunodeficiency virus (HIV) have inadequate access to antiretroviral therapy and ultimately develop debilitating oral infections that often correlate with disease progression. Our study evaluates the potential of simian immunodeficiency virus (SIV) infected rhesus macaques to serve as a non-human primate model for oral manifestations of HIV disease. Microarrays were used to characterize changes in gene expression in the tongue mucosa that occur during chronic SIV infection. Dorsal tongue tissues from healthy uninfected macaques and macaques with chronic stage SIV infection were used for RNA extraction and hybridization on Affymetrix microarrays.

Characteristics of participants by HIV and CDC status.