The various performance criteria applied in this analysis include the probability of reaching the ultimate target, the costs, elapsed times and system vulnerability resulting from any intrusion. This Excel file contains all the logical, probabilistic and statistical data entered by a user, and required for the evaluation of the criteria. It also reports the results of all the computations.

Time-Series Matrix (TSMx): A visualization tool for plotting multiscale temporal trends TSMx is an R script that was developed to facilitate multi-temporal-scale visualizations of time-series data. The script requires only a two-column CSV of years and values to plot the slope of the linear regression line for all possible year combinations from the supplied temporal range. The outputs include a time-series matrix showing slope direction based on the linear regression, slope values plotted with colors indicating magnitude, and results of a Mann-Kendall test. The start year is indicated on the y-axis and the end year is indicated on the x-axis. In the example below, the cell in the top-right corner is the direction of the slope for the temporal range 2001–2019. The red line corresponds with the temporal range 2010–2019 and an arrow is drawn from the cell that represents that range. One cell is highlighted with a black border to demonstrate how to read the chart—that cell represents the slope for the temporal range 2004–2014. This publication entry also includes an excel template that produces the same visualizations without a need to interact with any code, though minor modifications will need to be made to accommodate year ranges other than what is provided. TSMx for R was developed by Georgios Boumis; TSMx was originally conceptualized and created by Brad G. Peter in Microsoft Excel. Please refer to the associated publication: Peter, B.G., Messina, J.P., Breeze, V., Fung, C.Y., Kapoor, A. and Fan, P., 2024. Perspectives on modifiable spatiotemporal unit problems in remote sensing of agriculture: evaluating rice production in Vietnam and tools for analysis. Frontiers in Remote Sensing, 5, p.1042624. https://www.frontiersin.org/journals/remote-sensing/articles/10.3389/frsen.2024.1042624 TSMx sample chart from the supplied Excel template. Data represent the productivity of rice agriculture in Vietnam as measured via EVI (enhanced vegetation index) from the NASA MODIS data product (MOD13Q1.V006). TSMx R script: # import packages library(dplyr) library(readr) library(ggplot2) library(tibble) library(tidyr) library(forcats) library(Kendall) options(warn = -1) # disable warnings # read data (.csv file with "Year" and "Value" columns) data <- read_csv("EVI.csv") # prepare row/column names for output matrices years <- data %>% pull("Year") r.names <- years[-length(years)] c.names <- years[-1] years <- years[-length(years)] # initialize output matrices sign.matrix <- matrix(data = NA, nrow = length(years), ncol = length(years)) pval.matrix <- matrix(data = NA, nrow = length(years), ncol = length(years)) slope.matrix <- matrix(data = NA, nrow = length(years), ncol = length(years)) # function to return remaining years given a start year getRemain <- function(start.year) { years <- data %>% pull("Year") start.ind <- which(data[["Year"]] == start.year) + 1 remain <- years[start.ind:length(years)] return (remain) } # function to subset data for a start/end year combination splitData <- function(end.year, start.year) { keep <- which(data[['Year']] >= start.year & data[['Year']] <= end.year) batch <- data[keep,] return(batch) } # function to fit linear regression and return slope direction fitReg <- function(batch) { trend <- lm(Value ~ Year, data = batch) slope <- coefficients(trend)[[2]] return(sign(slope)) } # function to fit linear regression and return slope magnitude fitRegv2 <- function(batch) { trend <- lm(Value ~ Year, data = batch) slope <- coefficients(trend)[[2]] return(slope) } # function to implement Mann-Kendall (MK) trend test and return significance # the test is implemented only for n>=8 getMann <- function(batch) { if (nrow(batch) >= 8) { mk <- MannKendall(batch[['Value']]) pval <- mk[['sl']] } else { pval <- NA } return(pval) } # function to return slope direction for all combinations given a start year getSign <- function(start.year) { remaining <- getRemain(start.year) combs <- lapply(remaining, splitData, start.year = start.year) signs <- lapply(combs, fitReg) return(signs) } # function to return MK significance for all combinations given a start year getPval <- function(start.year) { remaining <- getRemain(start.year) combs <- lapply(remaining, splitData, start.year = start.year) pvals <- lapply(combs, getMann) return(pvals) } # function to return slope magnitude for all combinations given a start year getMagn <- function(start.year) { remaining <- getRemain(start.year) combs <- lapply(remaining, splitData, start.year = start.year) magns <- lapply(combs, fitRegv2) return(magns) } # retrieve slope direction, MK significance, and slope magnitude signs <- lapply(years, getSign) pvals <- lapply(years, getPval) magns <- lapply(years, getMagn) # fill-in output matrices dimension <- nrow(sign.matrix) for (i in 1:dimension) { sign.matrix[i, i:dimension] <- unlist(signs[i]) pval.matrix[i, i:dimension] <- unlist(pvals[i]) slope.matrix[i, i:dimension] <- unlist(magns[i]) } sign.matrix <-...

Figures in scientific publications are critically important because they often show the data supporting key findings. Our systematic review of research articles published in top physiology journals (n = 703) suggests that, as scientists, we urgently need to change our practices for presenting continuous data in small sample size studies. Papers rarely included scatterplots, box plots, and histograms that allow readers to critically evaluate continuous data. Most papers presented continuous data in bar and line graphs. This is problematic, as many different data distributions can lead to the same bar or line graph. The full data may suggest different conclusions from the summary statistics. We recommend training investigators in data presentation, encouraging a more complete presentation of data, and changing journal editorial policies. Investigators can quickly make univariate scatterplots for small sample size studies using our Excel templates.

The purpose of this project is to become comfortable with obtaining citizen science datasets and spreadsheet software systems (e.g., Excel), and to gain experience working with, analyzing, and visualizing scientific data. Students will work independently (pairs or small group optional) to create five different charts including graphs visualizing the data collected in the LOYNO Biodiversity Project.

In the attached Excel file, "Example Student Data", there are 6 sheets. There are three sheets with sample datasets, one for each of the three different exercise protocols described. Additionally, there are three sheets with sample graphs created using one of the three datasets. · Sheets 1 and 2: This is an example of a dataset and graph created from an exercise protocol designed to stress the creatine phosphate system. Here, the subject was a track and field athlete who threw the shot put for the DeSales University track team. The NIRS monitor was placed on the right triceps muscle, and the student threw the shot put six times with a minute rest in between throws. Data was collected telemetrically by the NIRS device and then downloaded after the student had completed the protocol. · Sheets 3 and 4: This is an example of a dataset and graph created from an exercise protocol designed to stress the glycolytic energy system. In this example, the subject performed continuous squat jumps for 30 seconds, followed by a 90 second rest period, for a total of three exercise bouts. The NIRS monitor was place on the left gastrocnemius muscle. Here again, data was collected telemetrically by the NIRS device and then downloaded after he had completed the protocol. · Sheets 5 and 6: In this example, the dataset and graph are from an exercise protocol designed to stress the oxidative system. Here, the student held a light-intensity, isometric biceps contraction (pushing against a table). The NIRS monitor was attached to the left biceps muscle belly. Here, data was collected by a student observing the SmO2 values displayed on a secondary device; specifically, a smartphone with the IPSensorMan APP displaying data. The recorder student observed and recorded the data on an Excel Spreadsheet, and marked the times that exercise began and ended on the Spreadsheet.

Graph Database Market Outlook

The global graph database market size was valued at USD 1.5 billion in 2023 and is projected to reach USD 8.5 billion by 2032, growing at a CAGR of 21.2% from 2024 to 2032. The substantial growth of this market is driven primarily by increasing data complexity, advancements in data analytics technologies, and the rising need for more efficient database management systems.

One of the primary growth factors for the graph database market is the exponential increase in data generation. As organizations generate vast amounts of data from various sources such as social media, e-commerce platforms, and IoT devices, the need for sophisticated data management and analysis tools becomes paramount. Traditional relational databases struggle to handle the complexity and interconnectivity of this data, leading to a shift towards graph databases which excel in managing such intricate relationships.

Another significant driver is the growing adoption of artificial intelligence (AI) and machine learning (ML) technologies. These technologies rely heavily on connected data for predictive analytics and decision-making processes. Graph databases, with their inherent ability to model relationships between data points effectively, provide a robust foundation for AI and ML applications. This synergy between AI/ML and graph databases further accelerates market growth.

Additionally, the increasing prevalence of personalized customer experiences across industries like retail, finance, and healthcare is fueling demand for graph databases. Businesses are leveraging graph databases to analyze customer behaviors, preferences, and interactions in real-time, enabling them to offer tailored recommendations and services. This enhanced customer experience translates to higher customer satisfaction and retention, driving further adoption of graph databases.

From a regional perspective, North America currently holds the largest market share due to early adoption of advanced technologies and the presence of key market players. However, significant growth is also anticipated in the Asia-Pacific region, driven by rapid digital transformation, increasing investments in IT infrastructure, and growing awareness of the benefits of graph databases. Europe is also expected to witness steady growth, supported by stringent data management regulations and a strong focus on data privacy and security.

Component Analysis

The graph database market can be segmented into two primary components: software and services. The software segment holds the largest market share, driven by extensive adoption across various industries. Graph database software is designed to create, manage, and query graph databases, offering features such as scalability, high performance, and efficient handling of complex data relationships. The growth in this segment is propelled by continuous advancements and innovations in graph database technologies. Companies are increasingly investing in research and development to enhance the capabilities of their graph database software products, catering to the evolving needs of their customers.

On the other hand, the services segment is also witnessing substantial growth. This segment includes consulting, implementation, and support services provided by vendors to help organizations effectively deploy and manage graph databases. As businesses recognize the benefits of graph databases, the demand for expert services to ensure successful implementation and integration into existing systems is rising. Additionally, ongoing support and maintenance services are crucial for the smooth operation of graph databases, driving further growth in this segment.

The increasing complexity of data and the need for specialized expertise to manage and analyze it effectively are key factors contributing to the growth of the services segment. Organizations often lack the in-house skills required to harness the full potential of graph databases, prompting them to seek external assistance. This trend is particularly evident in large enterprises, where the scale and complexity of data necessitate robust support services.

Moreover, the services segment is benefiting from the growing trend of outsourcing IT functions. Many organizations are opting to outsource their database management needs to specialized service providers, allowing them to focus on their core business activities. This shift towards outsourcing is further bolstering the demand for graph database services, driving market growth.

To create the dataset, the top 10 countries leading in the incidence of COVID-19 in the world were selected as of October 22, 2020 (on the eve of the second full of pandemics), which are presented in the Global 500 ranking for 2020: USA, India, Brazil, Russia, Spain, France and Mexico. For each of these countries, no more than 10 of the largest transnational corporations included in the Global 500 rating for 2020 and 2019 were selected separately. The arithmetic averages were calculated and the change (increase) in indicators such as profitability and profitability of enterprises, their ranking position (competitiveness), asset value and number of employees. The arithmetic mean values of these indicators for all countries of the sample were found, characterizing the situation in international entrepreneurship as a whole in the context of the COVID-19 crisis in 2020 on the eve of the second wave of the pandemic. The data is collected in a general Microsoft Excel table. Dataset is a unique database that combines COVID-19 statistics and entrepreneurship statistics. The dataset is flexible data that can be supplemented with data from other countries and newer statistics on the COVID-19 pandemic. Due to the fact that the data in the dataset are not ready-made numbers, but formulas, when adding and / or changing the values in the original table at the beginning of the dataset, most of the subsequent tables will be automatically recalculated and the graphs will be updated. This allows the dataset to be used not just as an array of data, but as an analytical tool for automating scientific research on the impact of the COVID-19 pandemic and crisis on international entrepreneurship. The dataset includes not only tabular data, but also charts that provide data visualization. The dataset contains not only actual, but also forecast data on morbidity and mortality from COVID-19 for the period of the second wave of the pandemic in 2020. The forecasts are presented in the form of a normal distribution of predicted values and the probability of their occurrence in practice. This allows for a broad scenario analysis of the impact of the COVID-19 pandemic and crisis on international entrepreneurship, substituting various predicted morbidity and mortality rates in risk assessment tables and obtaining automatically calculated consequences (changes) on the characteristics of international entrepreneurship. It is also possible to substitute the actual values identified in the process and following the results of the second wave of the pandemic to check the reliability of pre-made forecasts and conduct a plan-fact analysis. The dataset contains not only the numerical values of the initial and predicted values of the set of studied indicators, but also their qualitative interpretation, reflecting the presence and level of risks of a pandemic and COVID-19 crisis for international entrepreneurship.

Spreadsheets and graphs are powerful tools that make data come alive and tell a story. Now, use maps to see the story from another perspective. ArcGIS Maps for Office enables Microsoft Excel and PowerPoint users worldwide to ask location-related questions of data, get powerful insights, and make the best decisions. You can:Map your spreadsheet data – whether you want to see customer locations, ZIP code aggregations, custom sales territories and more – you can see it all.Add geographic context to your spreadsheet data and communicate these insights via interactive maps in PowerPoint.Gain insight into demographic, spending, behavior, and landscape information, among many more.Use the authoritative content on the ArcGIS platform to supplement your location data and add context to the locations in your spreadsheet.Securely share your maps with colleagues and stakeholders.Bring the power of the ArcGIS platform into your spreadsheets and presentations. To use ArcGIS Maps for Office you need an ArcGIS Online paid or trial subscription or a Portal for ArcGIS Named User License and Microsoft Office 2010, 2013, or 2016. Visit the online documentation for information on how to use this app.

Data underlying the figures in the publication “Catechol[4]arene: The Missing Chiral Member of the Calix[4]arene Family”, published in Org. Lett. 2020, 22, 14, 5506–5510. https://pubs.acs.org/doi/10.1021/acs.orglett.0c01864

Table of contents:

1. Scheme1NMRDataCompounds.mnova; Processed NMR data of all new and key compounds depicted in Scheme 1.

2. Scheme1GeneralProcedures.txt; Synthetic procedures of all new and key compounds depicted in Scheme 1.

3. Figure2XRayStructure.cif; X-ray crystal structure of (±)-1 depicted in Figure 2. (requires a program such as Mercury to open)

4. Figure2GeneralProcedure.txt; Crystal data and experimental for X-ray crystal structure depicted in Figure 2.

5. Figure3CDSpectroscopyData.xlsx; Experimental and computational data used to generate graphs in Figure 3.

6. Figure3Calculations.txt; Calculations used to generate graphs in Figure 3.

7. Figure4NMRDataTitrations.mnova; Processed NMR spectra used to generate graphs in Figure 4.

8. Figure4GeneralProcedures.txt; General procedures for NMR titrations performed to generate data for Figure 4.

9. Figure4bTitrationData.xlsx; Excel sheet containing the compiled data and generate the graphs of the titration experiment depicted in Figure 4b.

10. Figure4cTitrationData.xlsx; Excel sheet containing the compiled data and generate the graphs of the titration experiment depicted in Figure 4c.

11. Figure5NMRDataCompounds.mnova; Processed NMR data on the compounds used as guests in Figure 5.

12. Figure5NMRDataTitrations.mnova; Processed NMR data on the host-guest titrations in Figure 5.

13. Figure5GeneralProcedures.txt; General procedures for the experiments depicted in Figure 5.

14. Figure6NMRData.mnova; Processed NMR data used to generate Figure 6.

15. Figure7NMRDataCompounds.mnova; Processed NMR data on the compounds used as guests in Figure 7.

16. Figure7NMRDataTitrations.mnova; Processed NMR data on the host-guest titrations in Figure 7.

17. Figure5GeneralProcedures.txt; General procedures for the experiments depicted in Figure 7.

Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?:

This data set contains all the experimental raw data, analysis and source files for the final figures reported in the manuscript: "Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?". It is divided into five (1-5) zipped folders, named as the technique used to obtain the data. Each of them, where applicable, consists of three different subfolders (raw data, analysed data, final graph). Read below for more details.

1) ConfocalMicroscopy

1a) Raw_Data: the raw images are reported as .dat and .tif formats, divided into folders (according to date first yymmdd, and within the same day according to composition). Each folder contains a .txt file reporting the experimental details

1b) GUVs_Statistics - GUVs_Statistics.txt explains how we generated the bar plot shown in Fig. 1E

1c) Final_Graph - Figure_1B_1D.png is the figure representing figure 1B and 1D - Figure1E_%ofGUVswithCaMAdsorbptions.csv is the source file x-y of the bar plot shown in figure 1E (% of GUVs which showed adsorption of CaM over the total amount of measured GUVs) - Where_To_Find_Representative_Images.txt states the folders where the raw images chosen for figure 1 can be found

2) FCS 2a) Raw_Data: - 1_points: .ptu files - 2_points: .ht3 files - Raw_Data_Description.docx which compositions and conditions correspond to which point in the two data sets 2b) Final_Graphs: - Figure_2A.xlsx contains the x-y source file for figure 2A

2c) Analysis: - FCS_Fits.xlsx outcome of the global fitting procedure described in the .docx below (each group of points represents a certain composition and calcium concentration, read the Raw_Data_Description.docx in the FCS > Raw_Data) - Notes_for_FCS_Analysis.docx contains a brief description of the analysis of the autocorrelation curves

3) GPLaurdan 3a) Raw Data: all the spectra are stored in folders named by date (yymmdd_lipidcomposition_Laurdan) and are in both .FS and .txt formats

3b) GP calculations: contains all the .xlsx files calculating the GP values from the raw emission and excitation spectra

3c) Final_Graphs - Data_Processing_For_Fig_2D.csv contains the data processing from the GP values calculated from the spectra to the DeltaGP (GP with- GP without CaM) reported in fig. 2D - Figure_2C_2D.xlsx contains the x-y source file for the figure 2C and 2D

4) LiveCellsImaging

3a) Intensity_Protrusions_vs_Cell_Body: - contains all the .xlsx files calculating the intensity of the various images. File renamed by date (yymmdd) - All data in all excel sheets gathered in another Excel file to create a final graph

3b) Final_Graphs - Figure_S2B.xlsx contains the x-y source file for the figure S2B

5) LiveCellImaging_Raw_Data: it contains some of the images, which are given in .tif. They are divided by date (yymmdd) and each contains subfolders renamed by sample name, concentration of ionomycin. Within the subfolders, the images are divided into folders distinguishing the data acquired before and after the ionomycin treatment and the incubation time.

6) 211124_BioCev_Imaging_1 folder has the .jpg files of the time laps, these are shown in fig 1A and S2.

7) 211124_BioCev_Imaging_2 and 8) 211124_BioCev_Imaging_3 contain the images of HeLa cells expressing EGFP-CaM after treatment with ionomycin 200 nM (A1) and 1 uM (A2), respectively.

9) SPR

9a) Raw Data: - SPR_Raw_Data.xlsx x/y exported sensorgrams - the .jpg files of the software are also reported and named by lipid composition

9b) Final_Graph: - Fig.2B.xlsx contains the x-y source file for the figure 2B

9c) Analysis - SPR_Analysis.xlsx: excel file containing step-by-step (sheet by sheet) how we processed the raw data to obtain the final figure (details explained in the .docx below) - Analysis of SPR data_notes.docx: read me for detailed explanation

Spreadsheet Software Market Size And Forecast

Spreadsheet Software Market size was valued at USD 10.05 Billion in 2023 and is expected to reach USD 14.55 Billion by 2031, with a CAGR of 7.8% from 2024-2031.

Global Spreadsheet Software Market Drivers

The market drivers for the Spreadsheet Software Market can be influenced by various factors. These may include:

Increasing Data Volume: As organizations generate and collect more data, the need for efficient data analysis and management tools, such as spreadsheet software, grows. Rising Demand for Data Visualization: Users increasingly seek sophisticated tools to visualize data for better insights. Spreadsheet software can provide charts and graphs, making data interpretation easier.

Global Spreadsheet Software Market Restraints

Several factors can act as restraints or challenges for the Spreadsheet Software Market, These may include:

Market Saturation: Many organizations already use established spreadsheet software such as Microsoft Excel or Google Sheets. The reliance on these platforms can make it difficult for new entrants or alternative solutions to capture market share. High Competition: The market is highly competitive, with numerous players offering similar features and functionalities. This can lead to price wars and reduced profit margins for software providers.

All Comparisons of Differentially Expressed Genes - excel sheet containing the annotations and fold change values of the all the differentially expressed genes between the different clone comparisonsFinal List of Common Genes - excel sheet containing the list of genes that were commonly differentially expressed between all the aphid clone comparisons. Also contains table and bar chart presenting the number of times each candidate gene selected from previous literature was found in each aphid clone comparison.Non-direct and Direct Competition - excel sheet containing number of nymphs produced by all 6 clones on the 3 host plants in the non-direct competition, and the number of nymphs produced by the two clones NS and Viola in the direct competition experiment.sterror - excel sheet containing the means and standard error values of the 6 grouped resistant and susceptible clones in the non-direct competition experiment, used to make the bar plot for the non-direct competition experiment.sterror2 - excel sheet containing the means and standard error values of the resistant clone Viola and susceptible clone NS in the direct competition experiment, used to make the bar plot for the direct competition experiment.cabbagettest - excel sheet containing the number of nymphs produce by the 6 grouped resistant and susceptible clones on the 3 host plants, used to conduct the unpaired t tests to compare the reproductive performance of resistant and susceptible clones on the 3 different host plants when in not in competitiondirectcompetition - excel sheet containing the number of nymphs produce by the resistant clone Viola and susceptible clone NS on the 3 host plants, used to conduct the unpaired t tests comparing the reproductive performance of resistant and susceptible clones on the 3 different host plants when in direct competitionAPHID HOST SHIFT DISS Rscript - R script containing all my statistical tests: unpaired t tests of resistant and susceptible clones on the 3 host plants when in direct and non direct competition, and kruskal Wallis tests and post hoc Dunns test to identify significant differences between individual and resistant and susceptible clones on the different host plants. Also contains all my code for my bar charts for the non-direct and direct competition experiments and the code for my box plots showing the significant differences between individual clones and resistant and susceptible clones on the different host plants.Up and Down-regulated Genes Graph - excel sheet containing the number of and and down regulated genes in each aphid clone comparison and the bar graph generated from this data.

Excel sheet containing the data used in this manuscript to generate the graphs.

The Excel file contains multiple tabs, with each tab containing the data for a single figure. (XLSX)

Numerical data (Excel spreadsheet) that underly the graphs in Figs 2G, 2H, 4E, 5E, 6I, 6J, 7C,

The compressed folder contains 11 excel files each corresponding to a figure which is specified in the filename. Excel files are broken down into multiple sheets, each containing the data for an individual panel of a figure. (ZIP)

This spreadsheet contains the processed data used to generate the graphs and statistics in the manuscript and is divided by originating figures into different sheets. (XLSX)