This report discusses some problems that can arise when attempting to import PostScript images into R, when the PostScript image contains coordinate transformations that skew the image. There is a description of some new features in the ‘grImport’ package for R that allow these sorts of images to be imported into R successfully.

This report discusses some problems that can arise when attempting to import PostScript images into R, when the PostScript image contains coordinate transformations that skew the image. There is a description of some new features in the ‘grImport’ package for R that allow these sorts of images to be imported into R successfully.

Subscribers can find out export and import data of 23 countries by HS code or product’s name. This demo is helpful for market analysis.

77814 Global import shipment records of R Human with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

1869 Global import shipment records of Code R Red with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

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Subscribers can find out export and import data of 23 countries by HS code or product’s name. This demo is helpful for market analysis.

Author: Andrew J. FeltonDate: 5/5/2024

This R project contains the primary code and data (following pre-processing in python) used for data production, manipulation, visualization, and analysis and figure production for the study entitled:

"Global estimates of the storage and transit time of water through vegetation"

Please note that 'turnover' and 'transit' are used interchangeably in this project.

Data information:

The data folder contains key data sets used for analysis. In particular:

"data/turnover_from_python/updated/annual/multi_year_average/average_annual_turnover.nc" contains a global array summarizing five year (2016-2020) averages of annual transit, storage, canopy transpiration, and number of months of data. This is the core dataset for the analysis; however, each folder has much more data, including a dataset for each year of the analysis. Data are also available is separate .csv files for each land cover type. Oterh data can be found for the minimum, monthly, and seasonal transit time found in their respective folders. These data were produced using the python code found in the "supporting_code" folder given the ease of working with .nc and EASE grid in the xarray python module. R was used primarily for data visualization purposes. The remaining files in the "data" and "data/supporting_data"" folder primarily contain ground-based estimates of storage and transit found in public databases or through a literature search, but have been extensively processed and filtered here.

Code information

Python scripts can be found in the "supporting_code" folder.

Each R script in this project has a particular function:

01_start.R: This script loads the R packages used in the analysis, sets thedirectory, and imports custom functions for the project. You can also load in the main transit time (turnover) datasets here using the source() function.

02_functions.R: This script contains the custom function for this analysis, primarily to work with importing the seasonal transit data. Load this using the source() function in the 01_start.R script.

03_generate_data.R: This script is not necessary to run and is primarilyfor documentation. The main role of this code was to import and wranglethe data needed to calculate ground-based estimates of aboveground water storage.

04_annual_turnover_storage_import.R: This script imports the annual turnover andstorage data for each landcover type. You load in these data from the 01_start.R scriptusing the source() function.

05_minimum_turnover_storage_import.R: This script imports the minimum turnover andstorage data for each landcover type. Minimum is defined as the lowest monthlyestimate.You load in these data from the 01_start.R scriptusing the source() function.

06_figures_tables.R: This is the main workhouse for figure/table production and supporting analyses. This script generates the key figures and summary statistics used in the study that then get saved in the manuscript_figures folder. Note that allmaps were produced using Python code found in the "supporting_code"" folder.

304 Global import shipment records of R Salt with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

26 Global import shipment records of R Lume with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

4503 Global import shipment records of R Lubricant with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

9970 Global import shipment records of Motorcycle R with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

166 Global import shipment records of Red R Base with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

77 Global import shipment records of Dvd R with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

15 Global import shipment records of R Coat with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

434 Global import shipment records of Industrial Machine For R with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

Objective: To develop a clinical informatics pipeline designed to capture large-scale structured EHR data for a national patient registry.

Materials and Methods: The EHR-R-REDCap pipeline is implemented using R-statistical software to remap and import structured EHR data into the REDCap-based multi-institutional Merkel Cell Carcinoma (MCC) Patient Registry using an adaptable data dictionary.

Results: Clinical laboratory data were extracted from EPIC Clarity across several participating institutions. Labs were transformed, remapped and imported into the MCC registry using the EHR labs abstraction (eLAB) pipeline. Forty-nine clinical tests encompassing 482,450 results were imported into the registry for 1,109 enrolled MCC patients. Data-quality assessment revealed highly accurate, valid labs. Univariate modeling was performed for labs at baseline on overall survival (N=176) using this clinical informatics pipeline.

Conclusion: We demonstrate feasibility of the facile eLAB workflow. EHR data is successfully transformed, and bulk-loaded/imported into a REDCap-based national registry to execute real-world data analysis and interoperability.

Methods eLAB Development and Source Code (R statistical software):

eLAB is written in R (version 4.0.3), and utilizes the following packages for processing: DescTools, REDCapR, reshape2, splitstackshape, readxl, survival, survminer, and tidyverse. Source code for eLAB can be downloaded directly (https://github.com/TheMillerLab/eLAB).

eLAB reformats EHR data abstracted for an identified population of patients (e.g. medical record numbers (MRN)/name list) under an Institutional Review Board (IRB)-approved protocol. The MCCPR does not host MRNs/names and eLAB converts these to MCCPR assigned record identification numbers (record_id) before import for de-identification.

Functions were written to remap EHR bulk lab data pulls/queries from several sources including Clarity/Crystal reports or institutional EDW including Research Patient Data Registry (RPDR) at MGB. The input, a csv/delimited file of labs for user-defined patients, may vary. Thus, users may need to adapt the initial data wrangling script based on the data input format. However, the downstream transformation, code-lab lookup tables, outcomes analysis, and LOINC remapping are standard for use with the provided REDCap Data Dictionary, DataDictionary_eLAB.csv. The available R-markdown ((https://github.com/TheMillerLab/eLAB) provides suggestions and instructions on where or when upfront script modifications may be necessary to accommodate input variability.

The eLAB pipeline takes several inputs. For example, the input for use with the ‘ehr_format(dt)’ single-line command is non-tabular data assigned as R object ‘dt’ with 4 columns: 1) Patient Name (MRN), 2) Collection Date, 3) Collection Time, and 4) Lab Results wherein several lab panels are in one data frame cell. A mock dataset in this ‘untidy-format’ is provided for demonstration purposes (https://github.com/TheMillerLab/eLAB).

Bulk lab data pulls often result in subtypes of the same lab. For example, potassium labs are reported as “Potassium,” “Potassium-External,” “Potassium(POC),” “Potassium,whole-bld,” “Potassium-Level-External,” “Potassium,venous,” and “Potassium-whole-bld/plasma.” eLAB utilizes a key-value lookup table with ~300 lab subtypes for remapping labs to the Data Dictionary (DD) code. eLAB reformats/accepts only those lab units pre-defined by the registry DD. The lab lookup table is provided for direct use or may be re-configured/updated to meet end-user specifications. eLAB is designed to remap, transform, and filter/adjust value units of semi-structured/structured bulk laboratory values data pulls from the EHR to align with the pre-defined code of the DD.

Data Dictionary (DD)

EHR clinical laboratory data is captured in REDCap using the ‘Labs’ repeating instrument (Supplemental Figures 1-2). The DD is provided for use by researchers at REDCap-participating institutions and is optimized to accommodate the same lab-type captured more than once on the same day for the same patient. The instrument captures 35 clinical lab types. The DD serves several major purposes in the eLAB pipeline. First, it defines every lab type of interest and associated lab unit of interest with a set field/variable name. It also restricts/defines the type of data allowed for entry for each data field, such as a string or numerics. The DD is uploaded into REDCap by every participating site/collaborator and ensures each site collects and codes the data the same way. Automation pipelines, such as eLAB, are designed to remap/clean and reformat data/units utilizing key-value look-up tables that filter and select only the labs/units of interest. eLAB ensures the data pulled from the EHR contains the correct unit and format pre-configured by the DD. The use of the same DD at every participating site ensures that the data field code, format, and relationships in the database are uniform across each site to allow for the simple aggregation of the multi-site data. For example, since every site in the MCCPR uses the same DD, aggregation is efficient and different site csv files are simply combined.

Study Cohort

This study was approved by the MGB IRB. Search of the EHR was performed to identify patients diagnosed with MCC between 1975-2021 (N=1,109) for inclusion in the MCCPR. Subjects diagnosed with primary cutaneous MCC between 2016-2019 (N= 176) were included in the test cohort for exploratory studies of lab result associations with overall survival (OS) using eLAB.

Statistical Analysis

OS is defined as the time from date of MCC diagnosis to date of death. Data was censored at the date of the last follow-up visit if no death event occurred. Univariable Cox proportional hazard modeling was performed among all lab predictors. Due to the hypothesis-generating nature of the work, p-values were exploratory and Bonferroni corrections were not applied.

analyze the current population survey (cps) annual social and economic supplement (asec) with r the annual march cps-asec has been supplying the statistics for the census bureau's report on income, poverty, and health insurance coverage since 1948. wow. the us census bureau and the bureau of labor statistics ( bls) tag-team on this one. until the american community survey (acs) hit the scene in the early aughts (2000s), the current population survey had the largest sample size of all the annual general demographic data sets outside of the decennial census - about two hundred thousand respondents. this provides enough sample to conduct state- and a few large metro area-level analyses. your sample size will vanish if you start investigating subgroups b y state - consider pooling multiple years. county-level is a no-no. despite the american community survey's larger size, the cps-asec contains many more variables related to employment, sources of income, and insurance - and can be trended back to harry truman's presidency. aside from questions specifically asked about an annual experience (like income), many of the questions in this march data set should be t reated as point-in-time statistics. cps-asec generalizes to the united states non-institutional, non-active duty military population. the national bureau of economic research (nber) provides sas, spss, and stata importation scripts to create a rectangular file (rectangular data means only person-level records; household- and family-level information gets attached to each person). to import these files into r, the parse.SAScii function uses nber's sas code to determine how to import the fixed-width file, then RSQLite to put everything into a schnazzy database. you can try reading through the nber march 2012 sas importation code yourself, but it's a bit of a proc freak show. this new github repository contains three scripts: 2005-2012 asec - download all microdata.R down load the fixed-width file containing household, family, and person records import by separating this file into three tables, then merge 'em together at the person-level download the fixed-width file containing the person-level replicate weights merge the rectangular person-level file with the replicate weights, then store it in a sql database create a new variable - one - in the data table 2012 asec - analysis examples.R connect to the sql database created by the 'download all microdata' progr am create the complex sample survey object, using the replicate weights perform a boatload of analysis examples replicate census estimates - 2011.R connect to the sql database created by the 'download all microdata' program create the complex sample survey object, using the replicate weights match the sas output shown in the png file below 2011 asec replicate weight sas output.png statistic and standard error generated from the replicate-weighted example sas script contained in this census-provided person replicate weights usage instructions document. click here to view these three scripts for more detail about the current population survey - annual social and economic supplement (cps-asec), visit: the census bureau's current population survey page the bureau of labor statistics' current population survey page the current population survey's wikipedia article notes: interviews are conducted in march about experiences during the previous year. the file labeled 2012 includes information (income, work experience, health insurance) pertaining to 2011. when you use the current populat ion survey to talk about america, subract a year from the data file name. as of the 2010 file (the interview focusing on america during 2009), the cps-asec contains exciting new medical out-of-pocket spending variables most useful for supplemental (medical spending-adjusted) poverty research. confidential to sas, spss, stata, sudaan users: why are you still rubbing two sticks together after we've invented the butane lighter? time to transition to r. :D

1903 Global import shipment records of Blue R with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.

291 Global import shipment records of Xiameter R with prices, volume & current Buyer's suppliers relationships based on actual Global export trade database.