Sheet 1 (Raw-Data): The raw data of the study is provided, presenting the tagging results for the used measures described in the paper. For each subject, it includes multiple columns: A. a sequential student ID B an ID that defines a random group label and the notation C. the used notation: user Story or use Cases D. the case they were assigned to: IFA, Sim, or Hos E. the subject's exam grade (total points out of 100). Empty cells mean that the subject did not take the first exam F. a categorical representation of the grade L/M/H, where H is greater or equal to 80, M is between 65 included and 80 excluded, L otherwise G. the total number of classes in the student's conceptual model H. the total number of relationships in the student's conceptual model I. the total number of classes in the expert's conceptual model J. the total number of relationships in the expert's conceptual model K-O. the total number of encountered situations of alignment, wrong representation, system-oriented, omitted, missing (see tagging scheme below) P. the researchers' judgement on how well the derivation process explanation was explained by the student: well explained (a systematic mapping that can be easily reproduced), partially explained (vague indication of the mapping ), or not present.

Tagging scheme:
Aligned (AL) - A concept is represented as a class in both models, either

with the same name or using synonyms or clearly linkable names; Wrongly represented (WR) - A class in the domain expert model is incorrectly represented in the student model, either (i) via an attribute, method, or relationship rather than class, or (ii) using a generic term (e.g., user'' instead ofurban planner''); System-oriented (SO) - A class in CM-Stud that denotes a technical implementation aspect, e.g., access control. Classes that represent legacy system or the system under design (portal, simulator) are legitimate; Omitted (OM) - A class in CM-Expert that does not appear in any way in CM-Stud; Missing (MI) - A class in CM-Stud that does not appear in any way in CM-Expert.

All the calculations and information provided in the following sheets

originate from that raw data.

Sheet 2 (Descriptive-Stats): Shows a summary of statistics from the data collection,

including the number of subjects per case, per notation, per process derivation rigor category, and per exam grade category.

Sheet 3 (Size-Ratio):

The number of classes within the student model divided by the number of classes within the expert model is calculated (describing the size ratio). We provide box plots to allow a visual comparison of the shape of the distribution, its central value, and its variability for each group (by case, notation, process, and exam grade) . The primary focus in this study is on the number of classes. However, we also provided the size ratio for the number of relationships between student and expert model.

Sheet 4 (Overall):

Provides an overview of all subjects regarding the encountered situations, completeness, and correctness, respectively. Correctness is defined as the ratio of classes in a student model that is fully aligned with the classes in the corresponding expert model. It is calculated by dividing the number of aligned concepts (AL) by the sum of the number of aligned concepts (AL), omitted concepts (OM), system-oriented concepts (SO), and wrong representations (WR). Completeness on the other hand, is defined as the ratio of classes in a student model that are correctly or incorrectly represented over the number of classes in the expert model. Completeness is calculated by dividing the sum of aligned concepts (AL) and wrong representations (WR) by the sum of the number of aligned concepts (AL), wrong representations (WR) and omitted concepts (OM). The overview is complemented with general diverging stacked bar charts that illustrate correctness and completeness.

For sheet 4 as well as for the following four sheets, diverging stacked bar

charts are provided to visualize the effect of each of the independent and mediated variables. The charts are based on the relative numbers of encountered situations for each student. In addition, a "Buffer" is calculated witch solely serves the purpose of constructing the diverging stacked bar charts in Excel. Finally, at the bottom of each sheet, the significance (T-test) and effect size (Hedges' g) for both completeness and correctness are provided. Hedges' g was calculated with an online tool: https://www.psychometrica.de/effect_size.html. The independent and moderating variables can be found as follows:

Sheet 5 (By-Notation):

Model correctness and model completeness is compared by notation - UC, US.

Sheet 6 (By-Case):

Model correctness and model completeness is compared by case - SIM, HOS, IFA.

Sheet 7 (By-Process):

Model correctness and model completeness is compared by how well the derivation process is explained - well explained, partially explained, not present.

Sheet 8 (By-Grade):

Model correctness and model completeness is compared by the exam grades, converted to categorical values High, Low , and Medium.

In this project, I conducted a comprehensive analysis of retail and warehouse sales data to derive actionable insights. The primary objective was to understand sales trends, evaluate performance across channels, and identify key contributors to overall business success.

To achieve this, I transformed raw data into interactive Excel dashboards that highlight sales performance and channel contributions, providing a clear and concise representation of business metrics.

Key Highlights of the Project:

Created two dashboards: Sales Dashboard and Contribution Dashboard. Answered critical business questions, such as monthly trends, channel performance, and top contributors. Presented actionable insights with professional visuals, making it easy for stakeholders to make data-driven decisions.

To create the dataset, the top 10 countries leading in the incidence of COVID-19 in the world were selected as of October 22, 2020 (on the eve of the second full of pandemics), which are presented in the Global 500 ranking for 2020: USA, India, Brazil, Russia, Spain, France and Mexico. For each of these countries, no more than 10 of the largest transnational corporations included in the Global 500 rating for 2020 and 2019 were selected separately. The arithmetic averages were calculated and the change (increase) in indicators such as profitability and profitability of enterprises, their ranking position (competitiveness), asset value and number of employees. The arithmetic mean values of these indicators for all countries of the sample were found, characterizing the situation in international entrepreneurship as a whole in the context of the COVID-19 crisis in 2020 on the eve of the second wave of the pandemic. The data is collected in a general Microsoft Excel table. Dataset is a unique database that combines COVID-19 statistics and entrepreneurship statistics. The dataset is flexible data that can be supplemented with data from other countries and newer statistics on the COVID-19 pandemic. Due to the fact that the data in the dataset are not ready-made numbers, but formulas, when adding and / or changing the values in the original table at the beginning of the dataset, most of the subsequent tables will be automatically recalculated and the graphs will be updated. This allows the dataset to be used not just as an array of data, but as an analytical tool for automating scientific research on the impact of the COVID-19 pandemic and crisis on international entrepreneurship. The dataset includes not only tabular data, but also charts that provide data visualization. The dataset contains not only actual, but also forecast data on morbidity and mortality from COVID-19 for the period of the second wave of the pandemic in 2020. The forecasts are presented in the form of a normal distribution of predicted values and the probability of their occurrence in practice. This allows for a broad scenario analysis of the impact of the COVID-19 pandemic and crisis on international entrepreneurship, substituting various predicted morbidity and mortality rates in risk assessment tables and obtaining automatically calculated consequences (changes) on the characteristics of international entrepreneurship. It is also possible to substitute the actual values identified in the process and following the results of the second wave of the pandemic to check the reliability of pre-made forecasts and conduct a plan-fact analysis. The dataset contains not only the numerical values of the initial and predicted values of the set of studied indicators, but also their qualitative interpretation, reflecting the presence and level of risks of a pandemic and COVID-19 crisis for international entrepreneurship.

This article describes a free, open-source collection of templates for the popular Excel (2013, and later versions) spreadsheet program. These templates are spreadsheet files that allow easy and intuitive learning and the implementation of practical examples concerning descriptive statistics, random variables, confidence intervals, and hypothesis testing. Although they are designed to be used with Excel, they can also be employed with other free spreadsheet programs (changing some particular formulas). Moreover, we exploit some possibilities of the ActiveX controls of the Excel Developer Menu to perform interactive Gaussian density charts. Finally, it is important to note that they can be often embedded in a web page, so it is not necessary to employ Excel software for their use. These templates have been designed as a useful tool to teach basic statistics and to carry out data analysis even when the students are not familiar with Excel. Additionally, they can be used as a complement to other analytical software packages. They aim to assist students in learning statistics, within an intuitive working environment. Supplementary materials with the Excel templates are available online.

The link for the Excel project to download can be found on GitHub here. It includes the raw data, Pivot Tables, and an interactive dashboard with Pivot Charts and Slicers. The project also includes business questions and the formulas I used to answer. The image below is included for ease. https://www.googleapis.com/download/storage/v1/b/kaggle-user-content/o/inbox%2F12904052%2F61e460b5f6a1fa73cfaaa33aa8107bd5%2FBusinessQuestions.png?generation=1686190703261971&alt=media" alt=""> The link for the Tableau adjusted dashboard can be found here.

A screenshot of the interactive Excel dashboard is also included below for ease. https://www.googleapis.com/download/storage/v1/b/kaggle-user-content/o/inbox%2F12904052%2Fe581f1fce8afc732f7823904da9e4cce%2FScooter%20Dashboard%20Image.png?generation=1686190815608343&alt=media" alt="">

The USDA Agricultural Research Service (ARS) recently established SCINet , which consists of a shared high performance computing resource, Ceres, and the dedicated high-speed Internet2 network used to access Ceres. Current and potential SCINet users are using and generating very large datasets so SCINet needs to be provisioned with adequate data storage for their active computing. It is not designed to hold data beyond active research phases. At the same time, the National Agricultural Library has been developing the Ag Data Commons, a research data catalog and repository designed for public data release and professional data curation. Ag Data Commons needs to anticipate the size and nature of data it will be tasked with handling. The ARS Web-enabled Databases Working Group, organized under the SCINet initiative, conducted a study to establish baseline data storage needs and practices, and to make projections that could inform future infrastructure design, purchases, and policies. The SCINet Web-enabled Databases Working Group helped develop the survey which is the basis for an internal report. While the report was for internal use, the survey and resulting data may be generally useful and are being released publicly. From October 24 to November 8, 2016 we administered a 17-question survey (Appendix A) by emailing a Survey Monkey link to all ARS Research Leaders, intending to cover data storage needs of all 1,675 SY (Category 1 and Category 4) scientists. We designed the survey to accommodate either individual researcher responses or group responses. Research Leaders could decide, based on their unit's practices or their management preferences, whether to delegate response to a data management expert in their unit, to all members of their unit, or to themselves collate responses from their unit before reporting in the survey. Larger storage ranges cover vastly different amounts of data so the implications here could be significant depending on whether the true amount is at the lower or higher end of the range. Therefore, we requested more detail from "Big Data users," those 47 respondents who indicated they had more than 10 to 100 TB or over 100 TB total current data (Q5). All other respondents are called "Small Data users." Because not all of these follow-up requests were successful, we used actual follow-up responses to estimate likely responses for those who did not respond. We defined active data as data that would be used within the next six months. All other data would be considered inactive, or archival. To calculate per person storage needs we used the high end of the reported range divided by 1 for an individual response, or by G, the number of individuals in a group response. For Big Data users we used the actual reported values or estimated likely values. Resources in this dataset:Resource Title: Appendix A: ARS data storage survey questions. File Name: Appendix A.pdfResource Description: The full list of questions asked with the possible responses. The survey was not administered using this PDF but the PDF was generated directly from the administered survey using the Print option under Design Survey. Asterisked questions were required. A list of Research Units and their associated codes was provided in a drop down not shown here. Resource Software Recommended: Adobe Acrobat,url: https://get.adobe.com/reader/ Resource Title: CSV of Responses from ARS Researcher Data Storage Survey. File Name: Machine-readable survey response data.csvResource Description: CSV file includes raw responses from the administered survey, as downloaded unfiltered from Survey Monkey, including incomplete responses. Also includes additional classification and calculations to support analysis. Individual email addresses and IP addresses have been removed. This information is that same data as in the Excel spreadsheet (also provided).Resource Title: Responses from ARS Researcher Data Storage Survey. File Name: Data Storage Survey Data for public release.xlsxResource Description: MS Excel worksheet that Includes raw responses from the administered survey, as downloaded unfiltered from Survey Monkey, including incomplete responses. Also includes additional classification and calculations to support analysis. Individual email addresses and IP addresses have been removed.Resource Software Recommended: Microsoft Excel,url: https://products.office.com/en-us/excel

Raw data outputs 1-18 Raw data output 1. Differentially expressed genes in AML CSCs compared with GTCs as well as in TCGA AML cancer samples compared with normal ones. This data was generated based on the results of AML microarray and TCGA data analysis. Raw data output 2. Commonly and uniquely differentially expressed genes in AML CSC/GTC microarray and TCGA bulk RNA-seq datasets. This data was generated based on the results of AML microarray and TCGA data analysis. Raw data output 3. Common differentially expressed genes between training and test set samples the microarray dataset. This data was generated based on the results of AML microarray data analysis. Raw data output 4. Detailed information on the samples of the breast cancer microarray dataset (GSE52327) used in this study. Raw data output 5. Differentially expressed genes in breast CSCs compared with GTCs as well as in TCGA BRCA cancer samples compared with normal ones. Raw data output 6. Commonly and uniquely differentially expressed genes in breast cancer CSC/GTC microarray and TCGA BRCA bulk RNA-seq datasets. This data was generated based on the results of breast cancer microarray and TCGA BRCA data analysis. CSC, and GTC are abbreviations of cancer stem cell, and general tumor cell, respectively. Raw data output 7. Differential and common co-expression and protein-protein interaction of genes between CSC and GTC samples. This data was generated based on the results of AML microarray and STRING database-based protein-protein interaction data analysis. CSC, and GTC are abbreviations of cancer stem cell, and general tumor cell, respectively. Raw data output 8. Differentially expressed genes between AML dormant and active CSCs. This data was generated based on the results of AML scRNA-seq data analysis. Raw data output 9. Uniquely expressed genes in dormant or active AML CSCs. This data was generated based on the results of AML scRNA-seq data analysis. Raw data output 10. Intersections between the targeting transcription factors of AML key CSC genes and differentially expressed genes between AML CSCs vs GTCs and between dormant and active AML CSCs or the uniquely expressed genes in either class of CSCs. Raw data output 11. Targeting desirableness score of AML key CSC genes and their targeting transcription factors. These scores were generated based on an in-house scoring function described in the Methods section. Raw data output 12. CSC-specific targeting desirableness score of AML key CSC genes and their targeting transcription factors. These scores were generated based on an in-house scoring function described in the Methods section. Raw data output 13. The protein-protein interactions between AML key CSC genes with themselves and their targeting transcription factors. This data was generated based on the results of AML microarray and STRING database-based protein-protein interaction data analysis. Raw data output 14. The previously confirmed associations of genes having the highest targeting desirableness and CSC-specific targeting desirableness scores with AML or other cancers’ (stem) cells as well as hematopoietic stem cells. These data were generated based on a PubMed database-based literature mining. Raw data output 15. Drug score of available drugs and bioactive small molecules targeting AML key CSC genes and/or their targeting transcription factors. These scores were generated based on an in-house scoring function described in the Methods section. Raw data output 16. CSC-specific drug score of available drugs and bioactive small molecules targeting AML key CSC genes and/or their targeting transcription factors. These scores were generated based on an in-house scoring function described in the Methods section. Raw data output 17. Candidate drugs for experimental validation. These drugs were selected based on their respective (CSC-specific) drug scores. CSC is the abbreviation of cancer stem cell. Raw data output 18. Detailed information on the samples of the AML microarray dataset GSE30375 used in this study.

Excel spreadsheets by species (4 letter code is abbreviation for genus and species used in study, year 2010 or 2011 is year data collected, SH indicates data for Science Hub, date is date of file preparation). The data in a file are described in a read me file which is the first worksheet in each file. Each row in a species spreadsheet is for one plot (plant). The data themselves are in the data worksheet. One file includes a read me description of the column in the date set for chemical analysis. In this file one row is an herbicide treatment and sample for chemical analysis (if taken). This dataset is associated with the following publication: Olszyk , D., T. Pfleeger, T. Shiroyama, M. Blakely-Smith, E. Lee , and M. Plocher. Plant reproduction is altered by simulated herbicide drift toconstructed plant communities. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 36(10): 2799-2813, (2017).

Excel spreadsheet containing the underlying numerical data and statistical analysis for all figures and tables.

In the beginning, the case was just data for a company that did not indicate any useful information that would help decision-makers. In this case, I had to ask questions that could help extract and explore information that would help decision-makers improve and evaluate performance. But before that, I did some operations in the data to help me to analyze it accurately: 1- Understand the data. 2- Clean the data “By power query”. 3- insert some calculation and columns by power query. 4- Analysis to the data and Ask some Questions About Distribution What is the Number of Bikes Sold? What is the most region purchasing bikes? What is the Ave. income by gender & purchasing bikes? The Miles with Purchasing bikes? What is situation to age by purchasing & Count of bikes sold? About Consumer Behavior Home Owner by purchasing? Single or married & Age by purchasing? Having cars by purchasing? Education By purchasing? Occupation By purchasing?

And I notice the Most Situations Purchasing Bikes is: - North America “Region”. - Commute Distance 0-1 Miles. - The people who are in the middle age and single "169 Bikes". - People that having Bachelor's degree. - The Males who have the average income 60,124$. - People that having Professional occupation. - Home owners “325 Bikes”. - People who having 0 or 1 car. So, I Advise The give those slices more offers to increase the sell value.

Excel spreadsheet containing, in separate sheets, the underlying numerical data and statistical analysis for Figs panels 1B, 1C, 1F, 1G, 1H, 2C, 2D, 2E, 2F, 3A, 3B, 3D, 3E, 3G, 3H, 3J, 3L, 4C, 4D, 4F, 4G, 4J, 5C, 5D, 5E, 5F, 5G, 5J, 5K, 5L, 5M, 6A, 6B, 6C, 6G, 7A, 7B, 7C, 7H, S1C, S1D, S1E, S2D, S2E, S3A, S3B, S4C, S4E, S6A, S6B, S6D, S7A.

This repository contains the raw dataset associated to the scientific article "Stable psychological traits predict psychological perceived stress to COVID-19 outbreak”, by L. Flesia, V. Fietta, B. Segatto, M. Monaro. Data are contained in the excel file and organized as follows:

- the entire dataset used by the authors to perform statistical analysis

- the training set used by the authors to train and validate ML models

- the test set used by the authors to test the ML models

The "Legend" file contains the description of each variable in the excel file.

The step by step instructions to replicate the results of ML classification models, which are reported in the paper, including two .arff files containing the training and test set od data that can be directly run in WEKA software 3.9.

The "COVID-19 QUESTIONNAIRE" file contains the English version of the questions administered to participants.

This dataset contains one Excel sheet and five Word documents. In this dataset, Simulation.xlsx describes the parameter values used for the numerical analysis based on empirical data. In this Excel sheet, we calculated the values of each capped call-option model parameter. Computation of Table 2.docx and other documents show the results of the comparative statistics.

Spatial analysis and statistical summaries of the Protected Areas Database of the United States (PAD-US) provide land managers and decision makers with a general assessment of management intent for biodiversity protection, natural resource management, and recreation access across the nation. The PAD-US 3.0 Combined Fee, Designation, Easement feature class (with Military Lands and Tribal Areas from the Proclamation and Other Planning Boundaries feature class) was modified to remove overlaps, avoiding overestimation in protected area statistics and to support user needs. A Python scripted process ("PADUS3_0_CreateVectorAnalysisFileScript.zip") associated with this data release prioritized overlapping designations (e.g. Wilderness within a National Forest) based upon their relative biodiversity conservation status (e.g. GAP Status Code 1 over 2), public access values (in the order of Closed, Restricted, Open, Unknown), and geodatabase load order (records are deliberately organized in the PAD-US full inventory with fee owned lands loaded before overlapping management designations, and easements). The Vector Analysis File ("PADUS3_0VectorAnalysisFile_ClipCensus.zip") associated item of PAD-US 3.0 Spatial Analysis and Statistics ( https://doi.org/10.5066/P9KLBB5D ) was clipped to the Census state boundary file to define the extent and serve as a common denominator for statistical summaries. Boundaries of interest to stakeholders (State, Department of the Interior Region, Congressional District, County, EcoRegions I-IV, Urban Areas, Landscape Conservation Cooperative) were incorporated into separate geodatabase feature classes to support various data summaries ("PADUS3_0VectorAnalysisFileOtherExtents_Clip_Census.zip") and Comma-separated Value (CSV) tables ("PADUS3_0SummaryStatistics_TabularData_CSV.zip") summarizing "PADUS3_0VectorAnalysisFileOtherExtents_Clip_Census.zip" are provided as an alternative format and enable users to explore and download summary statistics of interest (Comma-separated Table [CSV], Microsoft Excel Workbook [.XLSX], Portable Document Format [.PDF] Report) from the PAD-US Lands and Inland Water Statistics Dashboard ( https://www.usgs.gov/programs/gap-analysis-project/science/pad-us-statistics ). In addition, a "flattened" version of the PAD-US 3.0 combined file without other extent boundaries ("PADUS3_0VectorAnalysisFile_ClipCensus.zip") allow for other applications that require a representation of overall protection status without overlapping designation boundaries. The "PADUS3_0VectorAnalysis_State_Clip_CENSUS2020" feature class ("PADUS3_0VectorAnalysisFileOtherExtents_Clip_Census.gdb") is the source of the PAD-US 3.0 raster files (associated item of PAD-US 3.0 Spatial Analysis and Statistics, https://doi.org/10.5066/P9KLBB5D ). Note, the PAD-US inventory is now considered functionally complete with the vast majority of land protection types represented in some manner, while work continues to maintain updates and improve data quality (see inventory completeness estimates at: http://www.protectedlands.net/data-stewards/ ). In addition, changes in protected area status between versions of the PAD-US may be attributed to improving the completeness and accuracy of the spatial data more than actual management actions or new acquisitions. USGS provides no legal warranty for the use of this data. While PAD-US is the official aggregation of protected areas ( https://www.fgdc.gov/ngda-reports/NGDA_Datasets.html ), agencies are the best source of their lands data.

Complete annotations for the tabular data are presented below. Tab Fig 1: (A) The heatmap data of G protein family members in the hippocampal tissue of 6-month-old Wildtype (n = 6) and 5xFAD (n = 6) mice; (B) The heatmap data of G protein family members in the cortical tissue of 6-month-old Wildtype (n = 6) and 5xFAD (n = 6) mice; (C) The data in the overlapping part of the Venn diagram (132 elements); (D) The data information for creating volcano plot; (E) The data information for creating heatmap of GPCR-related DEGs; (F) Expression of Gnb5 in the large sample dataset GSE44772; Control, n = 303; AD, n = 387; (H) Statistical analysis of Gnb5 protein levels from panel G; Wildtype, n = 4; 5xFAD, n = 4; (J) Statistical analysis of Gnb5 protein levels from panel I; Wildtype, n = 4; 5xFAD, n = 4; (L) Quantitative analysis of Gnb5 fluorescence intensity in 5xFAD and Wildtype groups; Wildtype, n = 4; 5xFAD, n = 4. Tab Fig 2: (D) qPCR data of Gnb5 knockout in hippocampal tissue; Gnb5F/F, n = 6; Gnb5-CCKO, n = 6; (E–I, L–N) Animal behavioral tests in mice, Gnb5F/F, n = 22; Gnb5-CCKO, n = 16; (E) Total distance traveled in the open field experiment; (F) Training curve in the Morris water maze (MWM); (F-day6) Data from the sixth day of MWM training; (G) Percentage of time spent by the mouse in the target quadrant in the MWM; (H) Statistical analysis of the number of times the mouse traverses the target quadrant in the MWM; (I) Latency to first reach the target quadrant in the MWM; (L) Baseline freezing percentage of mice in an identical testing context; (M) Percentage of freezing time of mice during the Context phase; (N) Percentage of freezing time of mice during the Cue phase. Tab Fig 3: (D–F, H) MWM tests in mice; Wildtype+AAV-GFP, n = 20; Wildtype+AAV-Gnb5-GFP, n = 23; 5xFAD + AAV-GFP, n = 23; 5xFAD + AAV-Gnb5-GFP, n = 26; (D) Training curve in the MWM; (D-day6) Data from the sixth day of MWM training; (E) Percentage of time spent in the target quadrant in the MWM; (F) Statistical analysis of the number of entries in the target quadrant in the MWM; (H) Movement speed of mice in the MWM; (I–K) The contextual fear conditioning test in mice; 5xFAD + AAV-GFP, n = 23; 5xFAD + AAV-Gnb5-GFP, n = 26; (I) Baseline freezing percentage of mice in an identical testing context; (J) Percentage of freezing time of mice during the Context phase; (K) Percentage of freezing time of mice during the Cue phase; (L) Total distance traveled in the open field test; (M) Percentage of time spent in the center area during the open field test. Tab Fig 4: (B, C) Quantification of Aβ plaques in the hippocampus sections from Wildtype and 5xFAD mice injected with either AAV-Gnb5 or AAV-GFP; Wildtype+AAV-GFP, n = 4; Wildtype+AAV-Gnb5-GFP, n = 4; 5xFAD + AAV-GFP, n = 4; 5xFAD + AAV-Gnb5-GFP, n = 4; (B) Quantification of Aβ plaques number; (C) Quantification of Aβ plaques size; (F, G) Quantification of Aβ pylaques from indicted mice lines; WT&Gnb5F/F&CamKIIa-CreERT+Vehicle, n = 4; 5xFAD&Gnb5F/F&CamKIIa-CreERT+Vehicle, n = 4; 5xFAD&Gnb5F/F&CamKIIa-CreERT+Tamoxifen, n = 4; (F) Quantification of Aβ plaque size; (G) Quantification of Aβ plaque number. Tab Fig 5: (B) Overexpression of Gnb5-AAV in 5xFAD mice affects the expression of proteins related to APP cleavage (BACE1, β-CTF, Nicastrin and APP); Statistical analysis of protein levels; n = 4, respectively; (D) Tamoxifen-induced Gnb5 knockdown in 5xFAD mice affects APP-cleaving proteins; Statistical analysis of protein levels; n = 4, respectively; (F) Gnb5-CCKO mice show altered expression of APP-cleaving proteins; Statistical analysis of protein levels; n = 6, respectively. Tab Fig 7: (C, D) Quantification of Aβ plaques in the overexpressed full-length Gnb5, truncated fragments, and mutant truncated fragment AAV in 5xFAD mice; n = 4, respectively; (C) Quantification of Aβ plaques size; (D) Quantification of Aβ plaques number; (F) Effect of overexpressing full-length Gnb5, truncated fragments, and mutant truncated fragment viruses on the expression of proteins related to APP cleavage process in 5xFAD; Statistical analysis of protein levels; n = 3, respectively. (XLSX)

Excel spreadsheet containing, in separate sheets, the underlying numerical data and statistical analysis for Figs 1B, 1C, 1E, 1F, 1G, 2A, 2B, 3, 4B, 4C, 4D, 4E, 4F, 4G, 5A, 5B, 5C, 5D, 5E, 6A, 6B, 6C, 6D, 8A, 8B, 8C, 8D, 9A, 9B, 9C, 9D, 10A, 10B, 10C, 10D, 10E, 10F, 10G, 10H, 11A, 11B, 11C, S1A, S1B, S1C, S1D, S2A, S2B, S2C, and S2D.

Introduction

We are enclosing the database used in our research titled "Concentration and Geospatial Modelling of Health Development Offices' Accessibility for the Total and Elderly Populations in Hungary", along with our statistical calculations. For the sake of reproducibility, further information can be found in the file Short_Description_of_Data_Analysis.pdf and Statistical_formulas.pdf

The sharing of data is part of our aim to strengthen the base of our scientific research. As of March 7, 2024, the detailed submission and analysis of our research findings to a scientific journal has not yet been completed.

The dataset was expanded on 23rd September 2024 to include SPSS statistical analysis data, a heatmap, and buffer zone analysis around the Health Development Offices (HDOs) created in QGIS software.

Short Description of Data Analysis and Attached Files (datasets):

Our research utilised data from 2022, serving as the basis for statistical standardisation. The 2022 Hungarian census provided an objective basis for our analysis, with age group data available at the county level from the Hungarian Central Statistical Office (KSH) website. The 2022 demographic data provided an accurate picture compared to the data available from the 2023 microcensus. The used calculation is based on our standardisation of the 2022 data. For xlsx files, we used MS Excel 2019 (version: 1808, build: 10406.20006) with the SOLVER add-in.

Hungarian Central Statistical Office served as the data source for population by age group, county, and regions: https://www.ksh.hu/stadat_files/nep/hu/nep0035.html, (accessed 04 Jan. 2024.) with data recorded in MS Excel in the Data_of_demography.xlsx file.

In 2022, 108 Health Development Offices (HDOs) were operational, and it's noteworthy that no developments have occurred in this area since 2022. The availability of these offices and the demographic data from the Central Statistical Office in Hungary are considered public interest data, freely usable for research purposes without requiring permission.

The contact details for the Health Development Offices were sourced from the following page (Hungarian National Population Centre (NNK)): https://www.nnk.gov.hu/index.php/efi (n=107). The Semmelweis University Health Development Centre was not listed by NNK, hence it was separately recorded as the 108th HDO. More information about the office can be found here: https://semmelweis.hu/egeszsegfejlesztes/en/ (n=1). (accessed 05 Dec. 2023.)

Geocoordinates were determined using Google Maps (N=108): https://www.google.com/maps. (accessed 02 Jan. 2024.) Recording of geocoordinates (latitude and longitude according to WGS 84 standard), address data (postal code, town name, street, and house number), and the name of each HDO was carried out in the: Geo_coordinates_and_names_of_Hungarian_Health_Development_Offices.csv file.

The foundational software for geospatial modelling and display (QGIS 3.34), an open-source software, can be downloaded from:

https://qgis.org/en/site/forusers/download.html. (accessed 04 Jan. 2024.)

The HDOs_GeoCoordinates.gpkg QGIS project file contains Hungary's administrative map and the recorded addresses of the HDOs from the

Geo_coordinates_and_names_of_Hungarian_Health_Development_Offices.csv file,

imported via .csv file.

The OpenStreetMap tileset is directly accessible from www.openstreetmap.org in QGIS. (accessed 04 Jan. 2024.)

The Hungarian county administrative boundaries were downloaded from the following website: https://data2.openstreetmap.hu/hatarok/index.php?admin=6 (accessed 04 Jan. 2024.)

HDO_Buffers.gpkg is a QGIS project file that includes the administrative map of Hungary, the county boundaries, as well as the HDO offices and their corresponding buffer zones with a radius of 7.5 km.

Heatmap.gpkg is a QGIS project file that includes the administrative map of Hungary, the county boundaries, as well as the HDO offices and their corresponding heatmap (Kernel Density Estimation).

A brief description of the statistical formulas applied is included in the Statistical_formulas.pdf.

Recording of our base data for statistical concentration and diversification measurement was done using MS Excel 2019 (version: 1808, build: 10406.20006) in .xlsx format.

• Aggregated number of HDOs by county: Number_of_HDOs.xlsx
• Standardised data (Number of HDOs per 100,000 residents): Standardized_data.xlsx
• Calculation of the Lorenz curve: Lorenz_curve.xlsx
• Calculation of the Gini index: Gini_Index.xlsx
• Calculation of the LQ index: LQ_Index.xlsx
• Calculation of the Herfindahl-Hirschman Index: Herfindahl_Hirschman_Index.xlsx
• Calculation of the Entropy index: Entropy_Index.xlsx
• Regression and correlation analysis calculation: Regression_correlation.xlsx

Using the SPSS 29.0.1.0 program, we performed the following statistical calculations with the databases Data_HDOs_population_without_outliers.sav and Data_HDOs_population.sav:

• Regression curve estimation with elderly population and number of HDOs, excluding outlier values (Types of analyzed equations: Linear, Logarithmic, Inverse, Quadratic, Cubic, Compound, Power, S, Growth, Exponential, Logistic, with summary and ANOVA analysis table): Curve_estimation_elderly_without_outlier.spv
• Pearson correlation table between the total population, elderly population, and number of HDOs per county, excluding outlier values such as Budapest and Pest County: Pearson_Correlation_populations_HDOs_number_without_outliers.spv.
• Dot diagram including total population and number of HDOs per county, excluding outlier values such as Budapest and Pest Counties: Dot_HDO_total_population_without_outliers.spv.
• Dot diagram including elderly (64<) population and number of HDOs per county, excluding outlier values such as Budapest and Pest Counties: Dot_HDO_elderly_population_without_outliers.spv
• Regression curve estimation with total population and number of HDOs, excluding outlier values (Types of analyzed equations: Linear, Logarithmic, Inverse, Quadratic, Cubic, Compound, Power, S, Growth, Exponential, Logistic, with summary and ANOVA analysis table): Curve_estimation_without_outlier.spv
• Dot diagram including elderly (64<) population and number of HDOs per county: Dot_HDO_elderly_population.spv
• Dot diagram including total population and number of HDOs per county: Dot_HDO_total_population.spv
• Pearson correlation table between the total population, elderly population, and number of HDOs per county: Pearson_Correlation_populations_HDOs_number.spv
• Regression curve estimation with total population and number of HDOs, (Types of analyzed equations: Linear, Logarithmic, Inverse, Quadratic, Cubic, Compound, Power, S, Growth, Exponential, Logistic, with summary and ANOVA analysis table): Curve_estimation_total_population.spv

For easier readability, the files have been provided in both SPV and PDF formats.

The translation of these supplementary files into English was completed on 23rd Sept. 2024.

If you have any further questions regarding the dataset, please contact the corresponding author: domjan.peter@phd.semmelweis.hu

The dataset consists of the responses collected from 300 pediatric preanesthesia questionnaires, covering medical history, anesthesia history, perinatal information, family history, current treatments, and recent clinical symptoms. It also includes the corresponding physician assessments used as the reference standard, with variables necessary for calculating sensitivity, specificity, predictive values, and Cohen’s kappa agreement. The file is structured in tabular format and was used for all statistical analyses reported in the article. All data have been fully anonymized, with no names, dates of birth, or any other direct identifiers included.

Abstract

The harmonized data set on health, created and published by the ERF, is a subset of Iraq Household Socio Economic Survey (IHSES) 2012. It was derived from the household, individual and health modules, collected in the context of the above mentioned survey. The sample was then used to create a harmonized health survey, comparable with the Iraq Household Socio Economic Survey (IHSES) 2007 micro data set.

----> Overview of the Iraq Household Socio Economic Survey (IHSES) 2012:

Iraq is considered a leader in household expenditure and income surveys where the first was conducted in 1946 followed by surveys in 1954 and 1961. After the establishment of Central Statistical Organization, household expenditure and income surveys were carried out every 3-5 years in (1971/ 1972, 1976, 1979, 1984/ 1985, 1988, 1993, 2002 / 2007). Implementing the cooperation between CSO and WB, Central Statistical Organization (CSO) and Kurdistan Region Statistics Office (KRSO) launched fieldwork on IHSES on 1/1/2012. The survey was carried out over a full year covering all governorates including those in Kurdistan Region.

The survey has six main objectives. These objectives are:

1. Provide data for poverty analysis and measurement and monitor, evaluate and update the implementation Poverty Reduction National Strategy issued in 2009.
2. Provide comprehensive data system to assess household social and economic conditions and prepare the indicators related to the human development.
3. Provide data that meet the needs and requirements of national accounts.
4. Provide detailed indicators on consumption expenditure that serve making decision related to production, consumption, export and import.
5. Provide detailed indicators on the sources of households and individuals income.
6. Provide data necessary for formulation of a new consumer price index number.

The raw survey data provided by the Statistical Office were then harmonized by the Economic Research Forum, to create a comparable version with the 2006/2007 Household Socio Economic Survey in Iraq. Harmonization at this stage only included unifying variables' names, labels and some definitions. See: Iraq 2007 & 2012- Variables Mapping & Availability Matrix.pdf provided in the external resources for further information on the mapping of the original variables on the harmonized ones, in addition to more indications on the variables' availability in both survey years and relevant comments.

Geographic coverage

National coverage: Covering a sample of urban, rural and metropolitan areas in all the governorates including those in Kurdistan Region.

Analysis unit

1- Household/family. 2- Individual/person.

Universe

The survey was carried out over a full year covering all governorates including those in Kurdistan Region.

Kind of data

Sample survey data [ssd]

Sampling procedure

----> Design:

Sample size was (25488) household for the whole Iraq, 216 households for each district of 118 districts, 2832 clusters each of which includes 9 households distributed on districts and governorates for rural and urban.

----> Sample frame:

Listing and numbering results of 2009-2010 Population and Housing Survey were adopted in all the governorates including Kurdistan Region as a frame to select households, the sample was selected in two stages: Stage 1: Primary sampling unit (blocks) within each stratum (district) for urban and rural were systematically selected with probability proportional to size to reach 2832 units (cluster). Stage two: 9 households from each primary sampling unit were selected to create a cluster, thus the sample size of total survey clusters was 25488 households distributed on the governorates, 216 households in each district.

----> Sampling Stages:

In each district, the sample was selected in two stages: Stage 1: based on 2010 listing and numbering frame 24 sample points were selected within each stratum through systematic sampling with probability proportional to size, in addition to the implicit breakdown urban and rural and geographic breakdown (sub-district, quarter, street, county, village and block). Stage 2: Using households as secondary sampling units, 9 households were selected from each sample point using systematic equal probability sampling. Sampling frames of each stages can be developed based on 2010 building listing and numbering without updating household lists. In some small districts, random selection processes of primary sampling may lead to select less than 24 units therefore a sampling unit is selected more than once , the selection may reach two cluster or more from the same enumeration unit when it is necessary.

Mode of data collection

Face-to-face [f2f]

Research instrument

----> Preparation:

The questionnaire of 2006 survey was adopted in designing the questionnaire of 2012 survey on which many revisions were made. Two rounds of pre-test were carried out. Revision were made based on the feedback of field work team, World Bank consultants and others, other revisions were made before final version was implemented in a pilot survey in September 2011. After the pilot survey implemented, other revisions were made in based on the challenges and feedbacks emerged during the implementation to implement the final version in the actual survey.

----> Questionnaire Parts:

The questionnaire consists of four parts each with several sections: Part 1: Socio – Economic Data: - Section 1: Household Roster - Section 2: Emigration - Section 3: Food Rations - Section 4: housing - Section 5: education - Section 6: health - Section 7: Physical measurements - Section 8: job seeking and previous job

Part 2: Monthly, Quarterly and Annual Expenditures: - Section 9: Expenditures on Non – Food Commodities and Services (past 30 days). - Section 10 : Expenditures on Non – Food Commodities and Services (past 90 days). - Section 11: Expenditures on Non – Food Commodities and Services (past 12 months). - Section 12: Expenditures on Non-food Frequent Food Stuff and Commodities (7 days). - Section 12, Table 1: Meals Had Within the Residential Unit. - Section 12, table 2: Number of Persons Participate in the Meals within Household Expenditure Other Than its Members.

Part 3: Income and Other Data: - Section 13: Job - Section 14: paid jobs - Section 15: Agriculture, forestry and fishing - Section 16: Household non – agricultural projects - Section 17: Income from ownership and transfers - Section 18: Durable goods - Section 19: Loans, advances and subsidies - Section 20: Shocks and strategy of dealing in the households - Section 21: Time use - Section 22: Justice - Section 23: Satisfaction in life - Section 24: Food consumption during past 7 days

Part 4: Diary of Daily Expenditures: Diary of expenditure is an essential component of this survey. It is left at the household to record all the daily purchases such as expenditures on food and frequent non-food items such as gasoline, newspapers…etc. during 7 days. Two pages were allocated for recording the expenditures of each day, thus the roster will be consists of 14 pages.

Cleaning operations

----> Raw Data:

Data Editing and Processing: To ensure accuracy and consistency, the data were edited at the following stages: 1. Interviewer: Checks all answers on the household questionnaire, confirming that they are clear and correct. 2. Local Supervisor: Checks to make sure that questions has been correctly completed. 3. Statistical analysis: After exporting data files from excel to SPSS, the Statistical Analysis Unit uses program commands to identify irregular or non-logical values in addition to auditing some variables. 4. World Bank consultants in coordination with the CSO data management team: the World Bank technical consultants use additional programs in SPSS and STAT to examine and correct remaining inconsistencies within the data files. The software detects errors by analyzing questionnaire items according to the expected parameter for each variable.

----> Harmonized Data:

• The SPSS package is used to harmonize the Iraq Household Socio Economic Survey (IHSES) 2007 with Iraq Household Socio Economic Survey (IHSES) 2012.
• The harmonization process starts with raw data files received from the Statistical Office.
• A program is generated for each dataset to create harmonized variables.
• Data is saved on the household and individual level, in SPSS and then converted to STATA, to be disseminated.

Response rate

Iraq Household Socio Economic Survey (IHSES) reached a total of 25488 households. Number of households refused to response was 305, response rate was 98.6%. The highest interview rates were in Ninevah and Muthanna (100%) while the lowest rates were in Sulaimaniya (92%).

The Eastern Partnership Risk Analysis Network (EaP-RAN) performs monthly exchanges of statistical data and information on the most recent irregular migration trends. This information is compiled at the level of the Frontex Risk Analysis Unit (RAU) and analysed in cooperation with the regional partners on a quarterly and annual basis. The annual reports offer a more in-depth analysis of the occurring developments and phenomena which impact the regional and common borders while the quarterly reports are meant to provide regular updates and identify emerging trends in order to maintain situational awareness. Both types of reports are aimed at offering support for strategic and operational decision making.

The Eastern Partnership Quarterly statistical overview is focused on quarterly developments for the seven key indicators of irregular migration: (1) detections of illegal border-crossing between BCPs; (2) detections of illegal border-crossing at BCPs; (3) refusals of entry; (4) detections of illegal stay; (5) asylum applications; (6) detections of facilitators; and (7) detections of fraudulent documents.

The backbone of this overview are monthly statistics provided within the framework of the EaP-RAN (Armenia, Azerbaijan, Belarus, Georgia, Moldova and Ukraine) and reference period statistics from common border sections of the neighbouring EU Member States and Schengen Associated Countries (Norway, Finland, Estonia, Latvia, Lithuania, Poland, Slovakia, Hungary and Romania). The data are processed, checked for errors and merged into an Excel database for further analysis.