A global phenomenon, known as the demographic transition, has seen life expectancy from birth increase rapidly over the past two centuries. In pre-industrial societies, the average life expectancy was around 24 years, and it is believed that this was the case throughout most of history, and in all regions. The demographic transition then began in the industrial societies of Europe, North America, and the West Pacific around the turn of the 19th century, and life expectancy rose accordingly. Latin America was the next region to follow, before Africa and most Asian populations saw their life expectancy rise throughout the 20th century.

Life expectancy in the United Kingdom was below 39 years in the year 1765, and over the course of the next two and a half centuries, it is expected to have increased by more than double, to 81.1 by the year 2020. Although life expectancy has generally increased throughout the UK's history, there were several times where the rate deviated from its previous trajectory. These changes were the result of smallpox epidemics in the late eighteenth and early nineteenth centuries, new sanitary and medical advancements throughout time (such as compulsory vaccination), and the First world War and Spanish Flu epidemic in the 1910s.

At the beginning of the 1840s, life expectancy from birth in Ireland was just over 38 years. However, this figure would see a dramatic decline with the beginning of the Great Famine in 1845, and dropped below 21 years in the second half of the decade (in 1849 alone, life expectancy fell to just 14 years). The famine came as a result of a Europe-wide potato blight, which had a disproportionally devastating impact on the Irish population due to the dependency on potatoes (particularly in the south and east), and the prevalence of a single variety of potato on the island that allowed the blight to spread faster than in other areas of Europe. Additionally, authorities forcefully redirected much of the country's surplus grain to the British mainland, which exacerbated the situation. Within five years, mass starvation would contribute to the deaths of over one million people on the island, while a further one million would emigrate; this also created a legacy of emigration from Ireland, which saw the population continue to fall until the mid-1900s, and the total population of the island is still well below its pre-famine level of 8.5 million people.

Following the end of the Great Famine, life expectancy would begin to gradually increase in Ireland, as post-famine reforms would see improvements in the living standards of the country’s peasantry, most notably the Land Wars, a largely successful series of strikes, boycotts and protests aimed at reform of the country's agricultural land distribution, which began in the 1870s and lasted into the 20th century. As these reforms were implemented, life expectancy in Ireland would rise to more than fifty years by the turn of the century. While this rise would slow somewhat in the 1910s, due to the large number of Irish soldiers who fought in the First World War and the Spanish Flu pandemic, as well as the period of civil unrest leading up to the island's partition in 1921, life expectancy in Ireland would rise greatly in the 20th century. In the second half of the 20th century, Ireland's healthcare system and living standards developed similarly to the rest of Western Europe, and today, it is often ranks among the top countries globally in terms of human development, GDP and quality of healthcare. With these developments, the increase in life expectancy from birth in Ireland was relatively constant in the first century of independence, and in 2020 is estimated to be 82 years.

Life expectancy in India was 25.4 in the year 1800, and over the course of the next 220 years, it has increased to almost 70. Between 1800 and 1920, life expectancy in India remained in the mid to low twenties, with the largest declines coming in the 1870s and 1910s; this was because of the Great Famine of 1876-1878, and the Spanish Flu Pandemic of 1918-1919, both of which were responsible for the deaths of up to six and seventeen million Indians respectively; as well as the presence of other endemic diseases in the region, such as smallpox. From 1920 onwards, India's life expectancy has consistently increased, but it is still below the global average.