We provide a unique dataset characterizing urban soil profiles and their complementary pre-urban reference soil profiles for carbon content, and a proxy for soil texture, by depth to 1.5m. The research effort interprets this data in the context of urbanization impacts on the soil ecosystem with hydrologic and geotechnical implications. This dataset is associated with the following publication: Herrmann, D., L. Schifman, and W. Shuster. Urbanization drives convergence in soil profile texture and carbon content. Environmental Research Letters. IOP Publishing LIMITED, Bristol, UK, 15(11): 114001, (2020).

Monumental fountain Locations Vienna ================================ The City of Vienna app provides the right information at the right time for everyone living in Vienna: direct answers, city map, real-time messages, news from the city. Direct answers: * to all areas of the city from towing to tick vaccination * Most used services at a glance * automatic search suggestions including direct answers from WienBot * Learns continuously through user input City map: * Detailed base map * Extensive map content of the city of Vienna (e.g. drinking fountain) * Search for addresses and map contents (e.g. stops) * Öffi Routing to entries * Free choice of address search (shops and restaurants or city of Vienna address service with stairs) News: * Real-time information * Departure times and road encyclopedia of the respective location * News from the city * City of Vienna Advantage Club (competitions for members) Profile: * Digital membership card of the City of Vienna Advantage Club * Management of real-time messages (disturbances Wiener Linien, weather warnings, events, civil protection, ...) * Settings, imprint, data protection

Protein-Protein, Genetic, and Chemical Interactions for Hauser BM (2022):Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. curated by BioGRID (https://thebiogrid.org); ABSTRACT: Eliciting antibodies to surface-exposed viral glycoproteins can generate protective responses that control and prevent future infections. Targeting conserved sites may reduce the likelihood of viral escape and limit the spread of related viruses with pandemic potential. Here we leverage rational immunogen design to focus humoral responses on conserved epitopes. Using glycan engineering and epitope scaffolding in boosting immunogens, we focus murine serum antibody responses to conserved receptor binding motif (RBM) and receptor binding domain (RBD) epitopes following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike imprinting. Although all engineered immunogens elicit a robust SARS-CoV-2-neutralizing serum response, RBM-focusing immunogens exhibit increased potency against related sarbecoviruses, SARS-CoV, WIV1-CoV, RaTG13-CoV, and SHC014-CoV; structural characterization of representative antibodies defines a conserved epitope. RBM-focused sera confer protection against SARS-CoV-2 challenge. Thus, RBM focusing is a promising strategy to elicit breadth across emerging sarbecoviruses without compromising SARS-CoV-2 protection. These engineering strategies are adaptable to other viral glycoproteins for targeting conserved epitopes.