In 1800, the population of the region of present-day India was approximately 169 million. The population would grow gradually throughout the 19th century, rising to over 240 million by 1900. Population growth would begin to increase in the 1920s, as a result of falling mortality rates, due to improvements in health, sanitation and infrastructure. However, the population of India would see it’s largest rate of growth in the years following the country’s independence from the British Empire in 1948, where the population would rise from 358 million to over one billion by the turn of the century, making India the second country to pass the billion person milestone. While the rate of growth has slowed somewhat as India begins a demographics shift, the country’s population has continued to grow dramatically throughout the 21st century, and in 2020, India is estimated to have a population of just under 1.4 billion, well over a billion more people than one century previously. Today, approximately 18% of the Earth’s population lives in India, and it is estimated that India will overtake China to become the most populous country in the world within the next five years.

In the past four centuries, the population of the United States has grown from a recorded 350 people around the Jamestown colony of Virginia in 1610, to an estimated 331 million people in 2020. The pre-colonization populations of the indigenous peoples of the Americas have proven difficult for historians to estimate, as their numbers decreased rapidly following the introduction of European diseases (namely smallpox, plague and influenza). Native Americans were also omitted from most censuses conducted before the twentieth century, therefore the actual population of what we now know as the United States would have been much higher than the official census data from before 1800, but it is unclear by how much. Population growth in the colonies throughout the eighteenth century has primarily been attributed to migration from the British Isles and the Transatlantic slave trade; however it is also difficult to assert the ethnic-makeup of the population in these years as accurate migration records were not kept until after the 1820s, at which point the importation of slaves had also been illegalized. Nineteenth century In the year 1800, it is estimated that the population across the present-day United States was around six million people, with the population in the 16 admitted states numbering at 5.3 million. Migration to the United States began to happen on a large scale in the mid-nineteenth century, with the first major waves coming from Ireland, Britain and Germany. In some aspects, this wave of mass migration balanced out the demographic impacts of the American Civil War, which was the deadliest war in U.S. history with approximately 620 thousand fatalities between 1861 and 1865. The civil war also resulted in the emancipation of around four million slaves across the south; many of whose ancestors would take part in the Great Northern Migration in the early 1900s, which saw around six million black Americans migrate away from the south in one of the largest demographic shifts in U.S. history. By the end of the nineteenth century, improvements in transport technology and increasing economic opportunities saw migration to the United States increase further, particularly from southern and Eastern Europe, and in the first decade of the 1900s the number of migrants to the U.S. exceeded one million people in some years. Twentieth and twenty-first century The U.S. population has grown steadily throughout the past 120 years, reaching one hundred million in the 1910s, two hundred million in the 1960s, and three hundred million in 2007. In the past century, the U.S. established itself as a global superpower, with the world's largest economy (by nominal GDP) and most powerful military. Involvement in foreign wars has resulted in over 620,000 further U.S. fatalities since the Civil War, and migration fell drastically during the World Wars and Great Depression; however the population continuously grew in these years as the total fertility rate remained above two births per woman, and life expectancy increased (except during the Spanish Flu pandemic of 1918).

Since the Second World War, Latin America has replaced Europe as the most common point of origin for migrants, with Hispanic populations growing rapidly across the south and border states. Because of this, the proportion of non-Hispanic whites, which has been the most dominant ethnicity in the U.S. since records began, has dropped more rapidly in recent decades. Ethnic minorities also have a much higher birth rate than non-Hispanic whites, further contributing to this decline, and the share of non-Hispanic whites is expected to fall below fifty percent of the U.S. population by the mid-2000s. In 2020, the United States has the third-largest population in the world (after China and India), and the population is expected to reach four hundred million in the 2050s.

The earliest point where scientists can make reasonable estimates for the population of global regions is around 10,000 years before the Common Era (or 12,000 years ago). Estimates suggest that Asia has consistently been the most populated continent, and the least populated continent has generally been Oceania (although it was more heavily populated than areas such as North America in very early years). Population growth was very slow, but an increase can be observed between most of the given time periods. There were, however, dips in population due to pandemics, the most notable of these being the impact of plague in Eurasia in the 14th century, and the impact of European contact with the indigenous populations of the Americas after 1492, where it took almost four centuries for the population of Latin America to return to its pre-1500 level. The world's population first reached one billion people in 1803, which also coincided with a spike in population growth, due to the onset of the demographic transition. This wave of growth first spread across the most industrially developed countries in the 19th century, and the correlation between demographic development and industrial or economic maturity continued until today, with Africa being the final major region to begin its transition in the late-1900s.

In 1498, Vasco da Gama became the first known European to sail to India by circumventing Africa, which ushered in a new age of European sea trade with Asia. Initially, Indian rulers were unimpressed and wary of the Portuguese, and Muslim traders in the region were hostile, but the Portuguese were able to assess what could be traded for exotic goods (mostly spices) and lucrative trade routes were established after subsequent journeys. Additionally, the Portuguese quickly learned that they had the technological advantage in conflict, and repelled attacks from their Muslim rivals. Fortified trading posts, known as factories, were then established along the African and Asian coasts to protect these trade routes, and these became the foundation upon which the Portuguese Empire (Europe's longest-lasting) was built.

Colonization and competition In 1494, the Treaty of Tordesillas saw Portugal and Spain draw a line through the Atlantic, with each crown laying claim to all non-Christian lands on their respective side. No other European power acknowledged these claims, but it would take almost a century for the British, Dutch, or French to begin establishing their own maritime empires; this meant that the Portuguese had a near-monopoly on the Indian spice trade for almost 100 years, and this was the century when their trade with Asia was most active. Portuguese traders not only did business with merchants in India, but they also explored further, and established trade routes with present-day China, Indonesia, and Japan, and even facilitated trade between these cultures. In the 1590s, the Dutch then followed the Portuguese model of empire building and quickly emerged as Portugal's biggest rival in Asia. VOC The Dutch and Portuguese were in conflict for over 60 years, across four continents, and the Asian and African conflicts are often referred to as the "Spice War". The Netherlands eventually usurped Portugal as the strongest European trading power in Asia by the mid-1600s. Most of the Dutch trade was done through the Dutch East India Company (VOC), which is often considered the most valuable company to have ever existed. In the 17th century, 56 percent of all ships that travelled from the given countries to Asia were Dutch, and the figure was over 44 percent in the following century. Such companies were not only trading enterprises, but also acted in the military and political interests of their respective crowns. The VOC went into decline in the mid-1700s, as the British Empire gained the upper hand in its rivalry with the Netherlands. The British East India Company then consolidated its power on the Indian subcontinent, and Dutch interests were largely centered in the East Indies (present-day Indonesia), which remained a Dutch colony until the Second World War. For France, its primary colonial power in Asia was in French Indochina, made up of present-day Cambodia, Laos, and Vietnam, although the seven European powers had trade connections all over Asia, and all competed or cooperated with one another at various points in these 300 years.

Life expectancy in India was 25.4 in the year 1800, and over the course of the next 220 years, it has increased to almost 70. Between 1800 and 1920, life expectancy in India remained in the mid to low twenties, with the largest declines coming in the 1870s and 1910s; this was because of the Great Famine of 1876-1878, and the Spanish Flu Pandemic of 1918-1919, both of which were responsible for the deaths of up to six and seventeen million Indians respectively; as well as the presence of other endemic diseases in the region, such as smallpox. From 1920 onwards, India's life expectancy has consistently increased, but it is still below the global average.