Nature Methods Impact Factor 2024-2025 - ResearchHelpDesk - Nature Methods is a monthly journal publishing novel methods and significant improvements to basic life sciences research techniques. All editorial decisions are made by a team of full-time professional editors. Nature Methods is a forum for the publication of novel methods and significant improvements to tried-and-tested basic research techniques in the life sciences. This monthly publication is aimed at a broad, interdisciplinary audience of academic and industry researchers actively involved in laboratory practice. It provides them with new tools to conduct their research and places a strong emphasis on the immediate practical relevance of the work presented. The journal publishes primary research papers as well as overviews of recent technical and methodological developments. We are actively seeking primary methods papers of relevance to the biological and biomedical sciences, including methods grounded in chemistry that have a practical application to the study of biological problems. To enhance the practical relevance of each paper, description of the method must be accompanied by its validation, its application to an important biological question and results illustrating its performance in comparison to available approaches. Articles are selected for publication that present broad interest, thorough assessments of methodological performance and comprehensive technical descriptions that facilitate immediate application. Specific areas of interest include, but are not limited to: Methods for nucleic acid manipulation, amplification and sequencing Methods for protein engineering, expression and purification Methods for proteomics, including mass spectrometry, analysis of binding interactions, microarray-based technologies, display techniques, analysis of post-translational modifications, glycobiology and metabolomics Methods for systems biology, including proteomics approaches, protein interaction analysis methods and genome wide expression and regulation profiling Biomolecular structural analysis technologies, including NMR and crystallography Chemical biology techniques, including chemical labeling, methods for expanding the genetic code and directed evolution Biophysical methods, including single molecule and lab-on-a-chip technologies Optical and non-optical imaging technologies, including probe design and labeling methods, microscopy, spectroscopy and in vivo imaging Techniques for the analysis and manipulation of gene expression, including epigenetics, gene targeting, transduction, RNA interference and microarray-based technologies Methods for cell culture and manipulation, including stem cells, single cell methods and lab-on-a-chip technologies Immunological techniques, including production of antibodies, antibody-based assays and immunolabeling Methods for the study of physiology and disease processes including cancer Methods involving model organisms and their manipulation and phenotyping Computational and bioinformatic methods for analysis, modeling or visualization of biological data Nanotechnology-based methods applied to basic biology

Nature Biotechnology Impact Factor 2024-2025 - ResearchHelpDesk - Nature Biotechnology is interested in the best research from across the field of Biotechnology; our broad scope ensures that work published reaches the widest possible audience. All editorial decisions are made by a team of full-time professional editors. Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical, agricultural and environmental sciences as well as covers the commercial, political, ethical, legal, and societal aspects of this research. The first function is fulfilled by the peer-reviewed research section, the second by the expository efforts in the front of the journal. We provide researchers with news about business; we provide the business community with news about research developments. The core areas in which we are actively seeking research papers include: molecular engineering of nucleic acids and proteins; molecular therapy (therapeutics genes, antisense, siRNAs, aptamers, DNAzymes, ribozymes, peptides, proteins); large-scale biology (genomics, functional genomics, proteomics, structural genomics, metabolomics, etc.); computational biology (algorithms and modeling), regenerative medicine (stem cells, tissue engineering, biomaterials); imaging technology; analytical biotechnology (sensors/detectors for analytes/macromolecules), applied immunology (antibody engineering, xenotransplantation, T-cell therapies); food and agricultural biotechnology; and environmental biotechnology. A comprehensive list of areas of interest is shown below. Strategies for controlling gene expression Strategies for manipulating gene structure Strategies for gene containment Technologies for analyzing gene function (e.g., arrays, SAGE) Technologies for analyzing gene structure/organization (e.g., molecular beacons) Chemogenomics or chemical genetics Pharmacogenomics/SNPs Computational analysis Technologies for analyzing/identifying protein structure/function (e.g., 2-D gels, mass spectrometry, yeast two-hybrid, SPR, NMR, arrays and chips) Structural genomics Computational analysis Technologies for analyzing/profiling metabolites (chromatography, mass spectrometry) Computational analysis Bioinformatics; algorithms; data deconvolution Modeling and systems biology: kinetics-based models and constraints-based models Rational approaches for proteins/antibodies/enzymes/drugs Molecular evolution Molecular breeding approaches Genetic manipulation of species of interest to modify or allow the production of a commercially or therapeutically relevant compound Computational analysis Mammalian cells Insect cells Bacteria Fungi Plant cells Targeting strategies Viral and nonviral vector strategies Reporter molecules Imaging approaches/technologies for visualizing whole animals, cells, or single molecules Computational analysis Gene therapy (targeting, expression, integration, immunogenicity) Antisense RNAi DNAzymes and ribozymes Nanomaterials for use in drug delivery or as therapeutics Nanomaterials for use in industrial biotechnology Nanosensors Nanosystems for imaging molecules and cells Antibody engineering T-cell therapies Therapies exploiting innate immunity (e.g. complement) Antigen delivery vectors and approaches Nucleic acid vaccines Computational analysis Stem cells Tissue engineering Therapeutic cloning (somatic cell nuclear transfer) Xenotransplantation Biomaterials Approaches for detecting biological molecules Use of biological systems in detecting analytes Approaches for multiplexing and increasing throughput Selection/screening strategies for gene/proteins/drugs Microfluidics Engineering materials for biological application Molecular imprinting Biomimetics Nanotechnology Crop improvement (resistance to stress, disease, pests) Nutraceuticals Forest biotechnology Plant vaccines Plants as bioreactors Gene-containment strategies Transgenic animals Knockouts Reproductive cloning Biopharmaceutical and enzyme production Transgene targeting and expression strategies Bioremediation Biomining Phytoremediation Monitoring