As of 2019, about ** percent of households across India were segmented as belonging to the NCCS C category of consumers. Contrariwise only **** percent of the country's population fell under the NCCS E category that year. Between 2014 and 2019, the share of population classified as category A, B, and C consumers has grown tremendously, reflecting the trajectory of the booming middle class within the Indian economy.
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NCCS-NSCLC-ITH2 dataset of 185 sectors from 48 patients with early-stage non-small cell lung cancer diagnosed in National Cancer Centre Singapore; these are paired-end, whole-exome and bulk RNA sequencing data, sequenced by Illumina HiSeq 4000/2000.
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Polish adaptation of the NCCS scale-discriminant power indicators and Cronbach's α coefficient.
This statistic displays the distribution of television viewership across India as of *************, by socio-economic class. Viewers from households classed as NCCS CDE contributed to around ** percent of the total television viewership in the country during the measured time period.
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Factor analysis, item-total scale correlations and reliability for the NCCS.
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Values for factor loadings of items included in the separated scales of the NCCS-P questionnaire.
These quarterly reports show the number of receipts, dispositions and pending New Court Cases (NCCs) during the defined period. The data shown is by month with quarterly and fiscal year (FY) summaries through the most recently completed quarter. Report for FY 2019.
Nepal Commercial Coffee Survey 2019 conducted by Central Bureau of Statistics (CBS), it is the first survey of Nepal. The main objective of the NCCS 2019 is to estimate the Production, sell and use of Coffee as well as contribution on GDP. The other specific objectives are to provide the statistical information of Nature, position, distribution and consumption of Coffee. Respondents of the survey are commercial coffee holders. The survey employs a purposive sample selection procedure from Random Sampling Methods. Holders are selected from 32 districts of all 4 provinces . The survey used only traditional paper questionnaires for data collection. The findings from the survey will be helptul to Nepal Govt. & Stakeholders for further policy making & improvement of quality of its future products and services.
National Coverage (National & Districts level)
Individual & Institutional of Coffee holdings
All the commercial coffee holdings.
Sample survey data [ssd]
The NCCS 2019 uses a purposive sample selection method. The total sample size is .............. holdings. Nepal Commercial Coffee Survey 2019 has total sampl size of....................
Face-to-face [f2f]
The survey employs traditional paper questionnaire.The questionnaire is divided into 7 sections as follows:
Section 1. Introduction Section 2. General Information Section 3: Employment Section 4: Use of Parcel Section 5: Production, Area & sell Section 6: Expenditure Statement Section 7: Loan Statement Section 8 : Misc.
For the consistency of data required logics were set in the data entry programme. For the processing and analysis of data SPSS and STATA programme were employed.
The response rate of this survey is 95 percent.
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Monthly Aggregated NEX-GDDP Ensemble Climate Projections: Historical (1985–2005) and RCP 4.5 and RCP 8.5 (2006–2080) This dataset is a monthly-scale aggregation of the NEX-GDDP: NASA Earth Exchange Global Daily Downscaled Climate Projections processed using Google Earth Engine (Gorelick 2017). The native delivery on Google Earth Engine is at the daily timescale for each individual CMIP5 GCM model. This dataset was created to facilitate use of NEX-GDDP and reduce processing times for projects that seek an ensemble model with a coarser temporal resolution. The aggregated data have been made available in Google Earth Engine via 'users/cartoscience/GCM_NASA-NEX-GDDP/NEX-GDDP-PRODUCT-ID_Ensemble-Monthly_YEAR' (see code below on how to access), and all 171 GeoTIFFS have been uploaded to this dataverse entry. Relevant links: https://www.nasa.gov/nex https://www.nccs.nasa.gov/services/data-collections/land-based-products/nex-gddp https://esgf.nccs.nasa.gov/esgdoc/NEX-GDDP_Tech_Note_v0.pdf https://developers.google.com/earth-engine/datasets/catalog/NASA_NEX-GDDP https://journals.ametsoc.org/view/journals/bams/93/4/bams-d-11-00094.1.xml https://rd.springer.com/article/10.1007/s10584-011-0156-z#page-1 The dataset can be accessed within Google Earth Engine using the following code: var histYears = ee.List.sequence(1985,2005).getInfo() var rcpYears = ee.List.sequence(2006,2080).getInfo() var path1 = 'users/cartoscience/GCM_NASA-NEX-GDDP/NEX-GDDP-' var path2 = '_Ensemble-Monthly_' var product product = 'Hist' var hist = ee.ImageCollection( histYears.map(function(y) { return ee.Image(path1+product+path2+y) }) ) product = 'RCP45' var rcp45 = ee.ImageCollection( rcpYears.map(function(y) { return ee.Image(path1+product+path2+y) }) ) product = 'RCP85' var rcp85 = ee.ImageCollection( rcpYears.map(function(y) { return ee.Image(path1+product+path2+y) }) ) print( 'Hist (1985–2005)', hist, 'RCP45 (2006–2080)', rcp45, 'RCP85 (2006–2080)', rcp85 ) var first = hist.first() var tMax = first.select('tasmin_1') var tMin = first.select('tasmax_1') var tMean = first.select('tmean_1') var pSum = first.select('pr_1') Map.addLayer(tMax, {min: -10, max: 40}, 'Average min temperature Jan 1985 (Hist)', false) Map.addLayer(tMin, {min: 10, max: 40}, 'Average max temperature Jan 1985 (Hist)', false) Map.addLayer(tMean, {min: 10, max: 40}, 'Average temperature Jan 1985 (Hist)', false) Map.addLayer(pSum, {min: 10, max: 500}, 'Accumulated rainfall Jan 1985 (Hist)', true) https://code.earthengine.google.com/5bfd9741274679dded7a95d1b57ca51d Ensemble average based on the following models: ACCESS1-0,BNU-ESM,CCSM4,CESM1-BGC,CNRM-CM5, CSIRO-Mk3-6-0,CanESM2,GFDL-CM3,GFDL-ESM2G, GFDL-ESM2M,IPSL-CM5A-LR,IPSL-CM5A-MR,MIROC-ESM-CHEM, MIROC-ESM,MIROC5,MPI-ESM-LR,MPI-ESM-MR,MRI-CGCM3, NorESM1-M,bcc-csm1-1,inmcm4 Each annual GeoTIFF contains 48 bands (4 variables across 12 months)— Temperature: Monthly mean (tasmin, tasmax, tmean) Precipitation: Monthly sum (pr) Bands 1–48 correspond with: tasmin_1, tasmax_1, tmean_1, pr_1, tasmin_2, tasmax_2, tmean_2, pr_2, tasmin_3, tasmax_3, tmean_3, pr_3, tasmin_4, tasmax_4, tmean_4, pr_4, tasmin_5, tasmax_5, tmean_5, pr_5, tasmin_6, tasmax_6, tmean_6, pr_6, tasmin_7, tasmax_7, tmean_7, pr_7, tasmin_8, tasmax_8, tmean_8, pr_8, tasmin_9, tasmax_9, tmean_9, pr_9, tasmin_10, tasmax_10, tmean_10, pr_10, tasmin_11, tasmax_11, tmean_11, pr_11, tasmin_12, tasmax_12, tmean_12, pr_12 *Gorelick, N., Hancher, M., Dixon, M., Ilyushchenko, S., Thau, D. and Moore, R., 2017. Google Earth Engine: Planetary-scale geospatial analysis for everyone. Remote Sensing of Environment, 202, pp.18–27. Project information: SEAGUL: Southeast Asia Globalization, Urbanization, Land and Environment Changes http://seagul.info/ https://lcluc.umd.edu/projects/divergent-local-responses-globalization-urbanization-land-transition-and-environmental This project was made possible by the the NASA Land-Cover/Land-Use Change Program (Grant #: 80NSSC20K0740)
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Waardenburg syndrome (WS) is an autosomal dominant inherited disorder that is characterized by sensorineural hearing loss and abnormal pigmentation. SOX10 is one of its main pathogenicity genes. The generation of patient-specific induced pluripotent stem cells (iPSCs) is an efficient means to investigate the mechanisms of inherited human disease. In our work, we set up an iPSC line derived from a WS patient with SOX10 mutation and differentiated into neural crest cells (NCCs), a key cell type involved in inner ear development. Compared with control-derived iPSCs, the SOX10 mutant iPSCs showed significantly decreased efficiency of development and differentiation potential at the stage of NCCs. After that, we carried out high-throughput RNA-seq and evaluated the transcriptional misregulation at every stage. Transcriptome analysis of differentiated NCCs showed widespread gene expression alterations, and the differentially expressed genes (DEGs) were enriched in gene ontology terms of neuron migration, skeletal system development, and multicellular organism development, indicating that SOX10 has a pivotal part in the differentiation of NCCs. It’s worth noting that, a significant enrichment among the nominal DEGs for genes implicated in inner ear development was found, as well as several genes connected to the inner ear morphogenesis. Based on the protein-protein interaction network, we chose four candidate genes that could be regulated by SOX10 in inner ear development, namely, BMP2, LGR5, GBX2, and GATA3. In conclusion, SOX10 deficiency in this WS subject had a significant impact on the gene expression patterns throughout NCC development in the iPSC model. The DEGs most significantly enriched in inner ear development and morphogenesis may assist in identifying the underlying basis for the inner ear malformation in subjects with WS.
S23 experiment: We sought to identify the microRNAs (miRNAs) enriched in the neural crest cell (NCC) population from E11.5 mouse embryos. To accomplish this, we utilized a transgenic mouse line harboring Cre-recombinase under the control of the Wnt1 NCC-specific promoter and also carrying the R26R-YFP allele. We sorted YFP+ (NCCs) and YFP- (non-NCCs) from E11.5 Wnt1Cre-R26R mouse embryos via FACS and compared the relative enrichment of miRNAs in the YFP+ population by miRNA microarray. 220 experiment: We sought to identify the microRNAs (miRNAs) enriched in the neural crest cell (NCC) population from E10.5 mouse embryos. To accomplish this, we utilized a transgenic mouse line harboring Cre-recombinase under the control of the Wnt1 NCC-specific promoter and also carrying the R26R-YFP allele. We sorted YFP+ (NCCs) and YFP- (non-NCCs) from E10.5 Wnt1Cre-R26R mouse embryos via FACS and compared the relative enrichment of miRNAs in the YFP+ population by miRNA microarray. 221 experiment: Our research has shown that heterozygous deletion of the miRNA processing enzyme Dicer leads to developmental delay of the thymus in mouse embryos. We sought to identify the microRNAs (miRNAs) affected by the loss of a single copy of Dicer in the neural crest cell (NCC) population from E10.5 mouse embryos. To accomplish this, we utilized a transgenic mouse line harboring a floxed allele of Dicer, Cre-recombinase under the control of the Wnt1 NCC-specific promoter, and also carrying the R26R-YFP allele. We sorted YFP+ (NCCs) cells from E10.5 Dicerfl/+,Wnt1Cre,R26R and Dicer+/+,Wnt1Cre,R26R mouse embryos via FACS and compared the relative expression of miRNAs in the Dicer-heterozygotes compared to Dicer-wildtypes by miRNA microarray. S23 experiment: RNA from YFP+ (NCCs) and YFP- (non-NCCs) cells sorted by FACS from E11.5 Wnt1Cre-R26R mouse embryos was isolated and hybridized to Exiqon miRNA microarrays v10. Cells from five E11.5 embryos were sorted into YFP+ and YFP- populations and pooled. 220 experiment: RNA from YFP+ (NCCs) and YFP- (non-NCCs) cells sorted by FACS from E10.5 Wnt1Cre-R26R mouse embryos was isolated and hybridized to Exiqon miRNA microarrays v10. Cells from ten E10.5 embryos were sorted into YFP+ and YFP- populations and pooled. 221 experiment: RNA from YFP+ (NCCs) cells sorted by FACS from E10.5 Dicerfl/+,Wnt1Cre,R26R and Dicer+/+,Wnt1Cre,R26R mouse embryos was isolated and hybridized to Exiqon miRNA microarrays v10. Cells from ten embryos were sorted into YFP+ populations and pooled for each genotype.
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The global market size for Nanometer Silver Cryptomorphic Condom (NCC) was estimated at USD 1.2 billion in 2023 and is forecasted to reach USD 3.5 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 12.3% during the forecast period. The market's robust growth can be attributed to increasing consumer awareness regarding sexual health and safety, advancements in nanotechnology, and rising demand for innovative and effective contraceptive solutions. Continuous innovation in materials and designs has enhanced the efficacy and appeal of NCCs, making them a popular choice among consumers.
One of the primary growth factors driving the NCC market is the rising awareness and emphasis on safe sexual practices. Governments and non-governmental organizations (NGOs) worldwide are actively promoting the use of condoms to prevent sexually transmitted infections (STIs) and unwanted pregnancies. Campaigns and educational programs have significantly increased the acceptance and use of condoms, including advanced versions like NCCs, which offer superior protection and comfort. The integration of nanometer silver technology provides additional antimicrobial properties, further enhancing the appeal of these products.
Technological advancements in nanotechnology and materials science have played a crucial role in the development of NCCs. The incorporation of nanometer-scale silver particles into the condom material offers enhanced antimicrobial properties, which can reduce the risk of infections. This unique feature is particularly appealing to health-conscious consumers who seek both effective contraception and additional health benefits. Furthermore, the development of ultra-thin and textured variants has catered to diverse consumer preferences, driving the market's growth.
The growing popularity of e-commerce and online retail platforms has also contributed significantly to the market's expansion. Online stores offer a wide range of NCC products, providing consumers with easy access to various options from the comfort of their homes. The convenience of discreet purchasing and the availability of detailed product information have made online retail a preferred distribution channel for many consumers. Additionally, the rise of specialty stores and pharmacies that stock a variety of contraceptive products has further boosted the market's growth.
Regional outlook for the NCC market indicates a strong growth trajectory across various geographies. North America and Europe have traditionally been the leading markets due to high levels of awareness and established healthcare systems. However, the Asia Pacific region is expected to witness the highest growth rate during the forecast period, driven by increasing awareness, improved access to healthcare products, and rising disposable incomes. Initiatives by governments and NGOs in countries like India and China to promote safe sexual practices are anticipated to further drive regional market growth.
The NCC market is segmented by product type into Standard NCC, Ultra-thin NCC, Textured NCC, and others. Standard NCCs are the most commonly used type, offering a balance of strength, comfort, and cost-effectiveness. These products cater to a broad audience, making them a staple in both personal and commercial use settings. The popularity of standard NCCs can be attributed to their proven reliability and widespread availability. Additionally, educational campaigns and promotions often feature standard NCCs, further solidifying their market presence.
Ultra-thin NCCs have gained significant traction among consumers seeking a more natural and sensitive experience. These condoms are designed to provide maximum sensation while maintaining the protective benefits of traditional condoms. The advancement in nanotechnology has enabled manufacturers to produce ultra-thin condoms without compromising on strength and durability. This segment is expected to witness substantial growth, driven by consumer preference for enhanced comfort and intimacy during sexual activity.
Textured NCCs cater to consumers looking for varied sensations and enhanced pleasure. These condoms feature different textures, such as ribbed or dotted patterns, designed to increase stimulation for both partners. The innovation in design and the promise of a more pleasurable experience have made textured NCCs a popular choice. Marketing campaigns highlighting these unique features have successfully attracted a demographic that values b
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Detailed NCCS-P characteristics of cultural competence of the nurses surveyed.
Die Karte zeigt die in den hydrologischen Szenarien Hydro-CH2018 berechneten prozentualen Veränderungen der Sommerabflüsse gegen Ende des Jahrhunderts (2070-2099) im Vergleich zur Referenzperiode (1981 – 2010) für ein Szenario ohne Klimaschutz (RCP8.5). Dargestellt ist jeweils der Median der gesamten Bandbreite aller Simulationen. Im Sommer zeigen die hydrologischen Szenarien eine mittlere Abflussabnahme von 30 - 50 % ohne Klimaschutz bis Ende des Jahrhunderts. Verantwortlich für diesen Rückgang sind verminderte Sommerniederschläge, höhere Verdunstung und die Abnahme des Gletscher- und Schneeschmelzwassers. Im Projekt Hydro-CH2018, das einen Themenschwerpunkt des National Centre for Climate Services (NCCS, www.nccs.admin.ch) bildet und vom BAFU geleitet wird, wurden je nach Fragestellung verschiedene, spezialisierte hydrologische Modelle eingesetzt. Aus diesem Grund ist es möglich, dass an gewissen Stationen mehrere, leicht unterschiedliche Resultate vorliegen, z.B. Thur bei Andelfingen (Details dazu können dem Synthesebericht «Auswirkungen des Klimawandels auf die Schweizer Gewässer » entnommen werden). Durch Anklicken des Links in den Objektinformationen gelangen Sie auf den Hydrologischen Atlas der Schweiz, wo sämtliche Resultate für alle Stationen, alle Klimaszenarien und alle Zeiträume inkl. Unsicherheitsbereich zu finden sind.
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The heterotrimeric G protein subunit Gsα couples receptors to activate adenylyl cyclase and is required for the intracellular cAMP response and protein kinase A (PKA) activation. Gsα is ubiquitously expressed in many cell types; however, the role of Gsα in neural crest cells (NCCs) remains unclear. Here we report that NCCs-specific Gsα knockout mice die within hours after birth and exhibit dramatic craniofacial malformations, including hypoplastic maxilla and mandible, cleft palate and craniofacial skeleton defects. Histological and anatomical analysis reveal that the cleft palate in Gsα knockout mice is a secondary defect resulting from craniofacial skeleton deficiencies. In Gsα knockout mice, the morphologies of NCCs-derived cranial nerves are normal, but the development of dorsal root and sympathetic ganglia are impaired. Furthermore, loss of Gsα in NCCs does not affect cranial NCCs migration or cell proliferation, but significantly accelerate osteochondrogenic differentiation. Taken together, our study suggests that Gsα is required for neural crest cells-derived craniofacial development.
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BackgroundCulture influences personal health habits and behavior, and healthcare personnel possess different views of cultural perspectives. Currently, an appropriate instrument to assess cultural competence in clinical practice is limited. The present study aimed to develop and examine the psychometric properties of the Nursing Cultural Competence Scale (NCCS) for clinical nurses.MethodsDeveloping and assessing the scale was carried out in two phases: Phase I involved a qualitative research to explore the themes of nurses’ cultural competence and instrument development; Phase II established construct validity of the scale using a sample of 246 nurses in Taiwan. Data from the questionnaire were analyzed using exploratory factor analysis, confirmatory factor analysis, internal consistency and test-retest reliability. Analysis results were used to determine the reliability and validity of the developed scale.ResultsThe results showed four factors including cultural awareness ability, cultural action ability, cultural resources application ability, and self-learning cultural ability were generated by exploratory factor analysis, and these factors explained 62.0% of total variance. Cronbach’s α of the Nursing Cultural Competence Scale was .88, and test-retest reliability correlation was .70.ConclusionsThe establishment of the tool will facilitate accurate monitoring of the cultural competence among nurses and nursing managers, which can inform the construction of nursing policies aimed at pledge cultural competence expansion.
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El mapa muestra los cambios porcentuales en las salidas de verano hacia finales de siglo (2070-2099) en comparación con el período de referencia (1981-2010) calculado en los escenarios hidrológicos Hydro-CH2018 para un escenario sin mitigación del cambio climático (RCP8.5). En cada caso, se muestra la mediana de todo el rango de todas las simulaciones. En verano, los escenarios hidrológicos muestran una disminución promedio de la escorrentía de 30 a 50% sin protección climática para fines de siglo. Esta disminución se debe a la reducción de las precipitaciones de verano, una mayor evaporación y la disminución del agua derretida de los glaciares y la nieve. En el proyecto Hydro-CH2018, que es un punto focal del Centro Nacional de Servicios Climáticos (NCCS, www.nccs.admin.ch) y está liderado por el FOEN, se utilizaron varios modelos hidrológicos especializados según la pregunta. Por esta razón, es posible que se disponga de varios resultados ligeramente diferentes en determinadas estaciones, por ejemplo, el jueves cerca de Andelfingen (pueden encontrarse detalles en el informe de síntesis «Impacto del cambio climático en las aguas suizas»). Al hacer clic en el enlace en la información del objeto le lleva al Atlas Hidrológico de Suiza, donde se pueden encontrar todos los resultados de todas las estaciones, todos los escenarios climáticos y todos los períodos, incluido el rango de incertidumbre. El mapa muestra los cambios porcentuales en las salidas de verano hacia finales de siglo (2070-2099) en comparación con el período de referencia (1981-2010) calculado en los escenarios hidrológicos Hydro-CH2018 para un escenario sin mitigación del cambio climático (RCP8.5). En cada caso, se muestra la mediana de todo el rango de todas las simulaciones. En verano, los escenarios hidrológicos muestran una disminución promedio de la escorrentía de 30 a 50% sin protección climática para fines de siglo. Esta disminución se debe a la reducción de las precipitaciones de verano, una mayor evaporación y la disminución del agua derretida de los glaciares y la nieve. En el proyecto Hydro-CH2018, que es un punto focal del Centro Nacional de Servicios Climáticos (NCCS, www.nccs.admin.ch) y está liderado por el FOEN, se utilizaron varios modelos hidrológicos especializados según la pregunta. Por esta razón, es posible que se disponga de varios resultados ligeramente diferentes en determinadas estaciones, por ejemplo, el jueves cerca de Andelfingen (pueden encontrarse detalles en el informe de síntesis «Impacto del cambio climático en las aguas suizas»). Al hacer clic en el enlace en la información del objeto le lleva al Atlas Hidrológico de Suiza, donde se pueden encontrar todos los resultados de todas las estaciones, todos los escenarios climáticos y todos los períodos, incluido el rango de incertidumbre.
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Characteristics of the group of nurses studied.
These quarterly reports show the number of receipts, dispositions and pending New Court Cases (NCCs) during the defined period. The data shown is by month with quarterly and fiscal year (FY) summaries through the most recently completed quarter. Report for FY 2022 (52 weeks).
As of 2019, about ** percent of households across India were segmented as belonging to the NCCS C category of consumers. Contrariwise only **** percent of the country's population fell under the NCCS E category that year. Between 2014 and 2019, the share of population classified as category A, B, and C consumers has grown tremendously, reflecting the trajectory of the booming middle class within the Indian economy.