Health Research Classification System (HRCS) is a bespoke system for classifying the full spectrum of biomedical and health research – from basic to applied – across all areas of health and disease.During the application process, we aim to determine the proportion it is aligned to HRCS by:Health Categories - the topic or disease of interestResearch Activities - the type of research See https://hrcsonline.net/ for further information including details of the taxonomies that our portfolios are coded against.This table also acts as a lookup table for the Consolidated View dataset.The dataset is updated quarterly, and the data in this edition is up to date as of the 31st March 2025.

The NIHR is one of the main funders of public health research in the UK. Public health research falls within the remit of a range of NIHR Research Programmes, NIHR Centres of Excellence and Facilities, plus the NIHR Academy. NIHR awards from all NIHR Research Programmes and the NIHR Academy that were funded between January 2006 and the present extraction date are eligible for inclusion in this dataset. An agreed inclusion/exclusion criteria is used to categorise awards as public health awards (see below). Following inclusion in the dataset, public health awards are second level coded to one of the four Public Health Outcomes Framework domains. These domains are: (1) wider determinants (2) health improvement (3) health protection (4) healthcare and premature mortality.More information on the Public Health Outcomes Framework domains can be found here.This dataset is updated quarterly to include new NIHR awards categorised as public health awards. Please note that for those Public Health Research Programme projects showing an Award Budget of £0.00, the project is undertaken by an on-call team for example, PHIRST, Public Health Review Team, or Knowledge Mobilisation Team, as part of an ongoing programme of work.Inclusion criteriaThe NIHR Public Health Overview project team worked with colleagues across NIHR public health research to define the inclusion criteria for NIHR public health research awards. NIHR awards are categorised as public health awards if they are determined to be ‘investigations of interventions in, or studies of, populations that are anticipated to have an effect on health or on health inequity at a population level.’ This definition of public health is intentionally broad to capture the wide range of NIHR public health awards across prevention, health improvement, health protection, and healthcare services (both within and outside of NHS settings). This dataset does not reflect the NIHR’s total investment in public health research. The intention is to showcase a subset of the wider NIHR public health portfolio. This dataset includes NIHR awards categorised as public health awards from NIHR Research Programmes and the NIHR Academy. This dataset does not currently include public health awards or projects funded by any of the three NIHR Research Schools or any of the NIHR Centres of Excellence and Facilities. Therefore, awards from the NIHR Schools for Public Health, Primary Care and Social Care, NIHR Public Health Policy Research Unit and the NIHR Health Protection Research Units do not feature in this curated portfolio.DisclaimersUsers of this dataset should acknowledge the broad definition of public health that has been used to develop the inclusion criteria for this dataset. This caveat applies to all data within the dataset irrespective of the funding NIHR Research Programme or NIHR Academy award.Please note that this dataset is currently subject to a limited data quality review. We are working to improve our data collection methodologies. Please also note that some awards may also appear in other NIHR curated datasets. Further informationFurther information on the individual awards shown in the dataset can be found on the NIHR’s Funding & Awards website here. Further information on individual NIHR Research Programme’s decision making processes for funding health and social care research can be found here.Further information on NIHR’s investment in public health research can be found as follows: NIHR School for Public Health here. NIHR Public Health Policy Research Unit here. NIHR Health Protection Research Units here. NIHR Public Health Research Programme Health Determinants Research Collaborations (HDRC) here. NIHR Public Health Research Programme Public Health Intervention Responsive Studies Teams (PHIRST) here.

The dataset contains awards funded by the NIHR which were active at any time on or after 1st April 2011. The dataset is updated quarterly, and the data in this edition are up to date as of the 31st March 2025. Please see the list here for the current scope of included NIHR Awards.

The NIHR Global Health Research Portfolio uses UK aid to fund high quality applied health research and training in areas of unmet need.The Portfolio funds research in developing countries that are eligible to receive Official Development Assistance (ODA) from the UK aid budget. This data file contains details of the Institutions who are the partners for awards. See here for more information on the Global Health programme. https://www.nihr.ac.uk/explore-nihr/funding-programmes/global-health.htm The dataset is updated quarterly, and the data in this edition is up to date as of the 31st March 2025.

This dataset contains the NIHR funded portfolio research awards; it has been consolidated with other datasets so the user does not need to complete their own cross referencing. These datasets are: NIHR Funded PortfolioNIHR Award HoldersNIHR Award HRCS Health Categories Coding and ApportionmentNIHR Award HRCS Research Activities Coding and Apportionment NIHR Curated PortfolioThis is updated quarterly, and the data in this edition are up to date as of the 31st March 2025.

This report aims to better understand the joint palliative and end of life care research portfolio of the National Institute for Health and Care Research (NIHR) and Marie Curie. The portfolio analysis brings together data from two UK-based research funders and is intended to inform ongoing strategic efforts to address gaps in the current evidence base. The need for palliative care has been conservatively estimated to be between 69 and 90% of all deaths in high-income countries (Murtagh, 2014; Fantoni et. al., 2023). Yet, palliative and end of life care has been shown to be one of the lowest funded areas of healthcare research in the UK. The UK Clinical Research Collaboration (UKCRC) Health ResearchClassification System (HRCS) 2018 dataset shows that only 0.21% of all non-commercial health-related project and programme research funding is spent on research focusing on palliative and end of life care (UKCRC, 2020).This portfolio analysis draws upon two data sources: a publicly available dataset of health-related research grants or awards active in 2018 (UKCRC, 2020) and created a new dataset (https://nihr.opendatasoft.com/explore/dataset/palliative-and-end-of-life-care/table/) of related research grants and awards from NIHR and Marie Curie (2011 – 2018/19). Analysis found that:In 2018, NIHR was the largest funder of palliative and end of life care research in the UK (46%), followed by Marie Curie as the second-largest funder overall (34%) and the largest charitable funder.The majority of NIHR and Marie Curie awards were projects, with relatively few personal awards.There was variation in investment across the UK, with host organisations located in Northern Ireland and the South West of England receiving least funding, followed by the West and East Midlands.Most awards were associated with ‘generic health relevance’ rather than a particular disease or condition. Where specific conditions were addressed, most awards concentrated on care for people with cancer, followed by neurological (mostly dementia) and respiratory conditions. Only a small number of awards addressed frailty, multimorbidity, Stroke, Oral/Gastrointestinal, Renal, Urogenital and Cardiovascular conditions, or Mental Health.Apart from age, there was very little research addressing relevant palliative and end of life care research questions with respect to protected characteristics.This analysis can be used by funders and researchers to continue to support efforts to fill gaps in the evidence base, and in response both funders have issued further calls for research.

A curated portfolio is developed to meet NIHR priority insight needs in areas not well supported by taxonomies such as the HRCS. An NIHR curated portfolio:Is a curated data set on a specific topics such as a health condition (e.g. diabetes), type of research, issue or other topic of strategic interest to the NIHRIs regularly updated (minimum annually)Contains data from more than one NIHR coordinating centreHas a clear definition with specific inclusion/exclusion criteria associated, co-developed with experts and PPIEThe NIHR curated portfolios are currently:Antimicrobial resistanceCOVID-19DiabetesDementiaMultiple long-term conditionsObesitySocial carePlease note: Awards may be duplicated if they are linked to more than one portfolio. Please see the two attachments below for the definitions used:For fill award information please see the NIHR Consolidated View.The dataset is updated quarterly, and the data in this edition is up to date as of the 31st March 2025.

This dataset allows the user to search for award holders and chief investigators, to identify relevant awards. The dataset is updated quarterly, and the data in this edition is up to date as of the 31st March 2025.

The latest geographical boundaries for the Integrated Care Boards, listed for data visualisations purposes, available for downloading.

These datasets and protocols are published on behalf of the Department of Health and Social Care, who have the written agreement of the named organisations. They are to be considered in conjunction with the Rare Diseases Research Landscape Project report - found here https://openresearch.nihr.ac.uk/documents/3-45. Please note: These are static datasets created for the purpose of this project, and there are currently no plans to update these datasets.The primary data set shown in the table is Dataset 1: NIHR Programmes & MRC combined It contains MRC and NIHR programme funding for research on rare diseases, from April 2016 – March 2022. Using the filter tool on the left-hand side menu, it is possible to filter this dataset to only display awards in the 5-year period that were analysed in the report. See report Section 3.The dataset includes columns with data relating to Orphanet, Health Research Classification System (HRCS) Health Categories and Research Activity Codes (RAC). For additional information see report Sections 3.2 and 3.3.Orphanet - report Section 3.2 and https://www.orpha.net/consor/cgi-bin/index.php HRCS Health Categories and RAC - report Section 3.3 and https://hrcsonline.net/ There are a further five datasets which are all available as attachments at the bottom of this web-page:Please note: Datasets 1, 2 and 4 are for an extended 6-year period (to March 2022), whereas the data analysed in the report focuses on a 5-year period (to March 2021), unless stated otherwise.Dataset 2: NIHR Programmes & MRC combined (includes rare neoplastic diseases and rare infectious diseases)The portfolio of MRC and NIHR programme funding for research on rare diseases as was defined for the report, from April 2016 – March 2022 (noting that for the majority of the analysis in the report, data from the 2021-22 financial year was not included). This dataset includes awards assigned to the ‘rare neoplastic diseases’ and ‘rare infectious diseases’ Orphanet groupings, which were not analysed as part of the report. See report Section 2.1.1.Dataset 3: NIHR infrastructure schemes supported studiesThe portfolio of NIHR funding that supports the physical facilities in which research is delivered and the workforce within those facilities that support the research delivery. This dataset only includes NIHR Coordinating Centre Infrastructure studies supported in the financial year 2020/2021. See report Section 3.6.1.Dataset 4: NIHR Clinical Research Network supported studiesThe portfolio of NIHR funding that invests in research expertise, specialist facilities, a research delivery workforce and support services which support and deliver research. This dataset includes CRN supported studies that were open to recruitment April 2016 – March 2022 (noting that data from the 2021-22 financial year was not included in the report analyses). See report Section 3.6.2.Dataset 5: Industry research and development (R&D) projects on rare diseases in the UK (1 April 2016 – 1 April 2021)This dataset contains the industry R&D projects on rare diseases (not including rare infectious or rare neoplastic diseases) in the UK (1 April 2016 – 1 April 2021) that were sourced from the commissioned search of Clarivate’s Cortellis Competitive Intelligence dataset, and is made available on an as-is basis. See report Section 4.1.Dataset 6: LifeArc rare disease research portfolioThis dataset contains information about the projects that LifeArc identified in their portfolio that were related to rare disease research in the 2016-2021 time-frame (not including projects on rare infectious or rare neoplastic diseases). See report paragraph 4.2.3.8.Protocol: This is the protocol that was developed by the Project Group to perform a detailed search of the entire NIHR and MRC portfolios, to identify research funding relevant to rare diseases. This protocol is explained in Annex 1 of the report. There are 5 annexes associated with this protocol in total. Annexes 1, 4 and 5 are in the protocol. Annexes 2 and 3 are provided here as separate csv files.

The NIHR invests significantly in centres of excellence, collaborations, services and facilities to support research in England. Collectively these form the NIHR research infrastructure. We award more than £606 million of funding per year to world leading NHS organisations and academic institutions with a proven, international track record in health and care research. The funding awards are significant multi-million-pound investments. Our significant and sustained research infrastructure funding supports the country’s leading experts in world-class research organisations. NIHR research infrastructure funding provides a platform to enable research, acting as a targeted and strategic investment to create an environment where early stage and applied research can thrive. Our research infrastructure provides research expertise, specialist facilities, a research delivery workforce and support services which all help to support and deliver the research we fund, and research funded by others. Research funded by UK Research and Innovation (UKRI), medical research charities, the life sciences industry (biopharmaceuticals, medtech, genomics, diagnostics and digital health), and other relevant industries all benefit from the network of services and support that we provide. This is an NIHR research infrastructure dataset and excludes the Research Delivery Network (RDN). The dataset is accurate as of the end of the 2023/24 financial year and is updated annually. It shows studies supported by the Applied Health and Social Care Research Collaborations (ARCs), Biomedical Research Centres (BRCs), Clinical Research Facilities (CRFs), Medtech and In vitro diagnostics Co-operatives (MICs) and Patient Safety Research Collaborations (PSRCs). Projects appear as duplicates if they have been reported by multiple Infrastructure Centres in multiple years. Using this dataset, users can search for projects that were supported by the abovementioned NIHR Infrastructure schemes by financial year.

Please note that this is not a complete dataset as commercially or otherwise sensitive projects have been withheld from it. Additionally, this dataset has been created to recognise the research infrastructure support that these studies have received and therefore it does not contain information about the support and funding received from other sources (e.g., other funding bodies or the life sciences industry).

NIHR HSDR Evidence Synthesis Teams and Rapid Evaluation Teams

This dataset contains information on the

projects conducted by the NIHR Health and Social Care Delivery Research Programme’s Evidence Synthesis Teams, Rapid Evaluation Teams and National Evaluation Teams.

Evidence Synthesis Teams provide timely and contextualised access to the

best research evidence on topics of key importance to health and social care organisations such as the NHS. Their work mainly consists of scoping reviews, rapid reviews, systematic reviews and other evidence synthesis methods.

Rapid Evaluation Teams deploy rapidly to conduct evaluations of health and

social care service innovations over a short period of time (usually 6 to 12 months). National Evaluation Teams deploy in a similar way but conduct evaluations over 1-3 years. This dataset will be updated every six months, and the data in this edition is accurate as of April 2025.

The latest geographical boundaries for the Westminster Parliamentary Constituencies, listed for data visualisations purposes, available for downloading.