37 datasets found
  1. Share of the U.S. population with schizophrenia from 1990 to 2019

    • statista.com
    • ai-chatbox.pro
    Updated Nov 29, 2023
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    Statista (2023). Share of the U.S. population with schizophrenia from 1990 to 2019 [Dataset]. https://www.statista.com/statistics/981206/schizophrenia-us-share-of-population/
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    Dataset updated
    Nov 29, 2023
    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    United States
    Description

    This statistic depicts the share of the U.S. population who suffered from schizophrenia from 1990 to 2019. As of 2019, around 0.47 percent of the population had schizophrenia.

  2. Share of the U.S. population with schizophrenia from 1990 to 2019, by gender...

    • statista.com
    Updated Nov 29, 2023
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    Statista (2023). Share of the U.S. population with schizophrenia from 1990 to 2019, by gender [Dataset]. https://www.statista.com/statistics/981232/schizophrenia-us-share-of-population-by-gender/
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    Dataset updated
    Nov 29, 2023
    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    United States
    Description

    This statistic depicts the share of the U.S. population that were diagnosed with schizophrenia from 1990 to 2019, by gender. As of 2019, around .46 percent of females and .48 percent of males had schizophrenia.

  3. Prevalence of mental health disorders in Italy 2023, by diagnosis

    • statista.com
    • ai-chatbox.pro
    Updated Jun 23, 2025
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    Statista (2025). Prevalence of mental health disorders in Italy 2023, by diagnosis [Dataset]. https://www.statista.com/statistics/808470/number-of-patients-of-mental-health-departments-by-diagnosis-in-italy/
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    Dataset updated
    Jun 23, 2025
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2023
    Area covered
    Italy
    Description

    In 2023, about ***** per 10 thousand individuals in Italy were treated for some kind of mental health disorder. This statistic breaks down this figure by diagnosis. According to the data, the most common mental health disorders treated among the Italian population were depression, schizophrenia, and psychoses. The diagnosis-related groups registering the lowest prevalence were dementia, organic mental disorders, alcoholism, and drug addiction. Mental health and gender Gender plays a relevant role in mental health, in the probability specific mental disorders will occur and in the decision to seek help. Women, for example, are more prone to suffer from depression, while men from schizophrenia and psychoses. In 2021, roughly **** women per 10,000 inhabitants were suffering from depression, while this figure was **** per 10,000 men. During the same period, the highest rate of patients treated in mental health wards was among women. Mental health ward patients The number of people that are treated in mental health wards in Italy varies greatly across the country. In 2021, the region with the highest number of mental health ward patients was Lombardy, with over *** thousand, followed by the regions of Campania and Emilia Romagna, with ** thousand and almost ** thousand patients, respectively. During the same period, most of the patients treated in mental health wards in Italy were aged between 45 and 64 years.

  4. d

    Mental Health of Children and Young People Surveys

    • digital.nhs.uk
    Updated Nov 29, 2022
    + more versions
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    (2022). Mental Health of Children and Young People Surveys [Dataset]. https://digital.nhs.uk/data-and-information/publications/statistical/mental-health-of-children-and-young-people-in-england
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    Dataset updated
    Nov 29, 2022
    License

    https://digital.nhs.uk/about-nhs-digital/terms-and-conditionshttps://digital.nhs.uk/about-nhs-digital/terms-and-conditions

    Description

    This report presents findings from the third (wave 3) in a series of follow up reports to the 2017 Mental Health of Children and Young People (MHCYP) survey, conducted in 2022. The sample includes 2,866 of the children and young people who took part in the MHCYP 2017 survey. The mental health of children and young people aged 7 to 24 years living in England in 2022 is examined, as well as their household circumstances, and their experiences of education, employment and services and of life in their families and communities. Comparisons are made with 2017, 2020 (wave 1) and 2021 (wave 2), where possible, to monitor changes over time.

  5. Long-Acting Schizophrenia Drug Market Report | Global Forecast From 2025 To...

    • dataintelo.com
    csv, pdf, pptx
    Updated Sep 23, 2024
    + more versions
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    Dataintelo (2024). Long-Acting Schizophrenia Drug Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/global-long-acting-schizophrenia-drug-market
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    pdf, pptx, csvAvailable download formats
    Dataset updated
    Sep 23, 2024
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Long-Acting Schizophrenia Drug Market Outlook



    The global market size for long-acting schizophrenia drugs was valued at approximately USD 4.5 billion in 2023 and is projected to reach USD 7.3 billion by 2032, growing at a compound annual growth rate (CAGR) of 5.4% during the forecast period. This growth is driven by several factors including advancements in drug formulations, increasing prevalence of schizophrenia, and rising awareness about mental health issues.



    One of the primary growth factors in the long-acting schizophrenia drug market is the increasing prevalence of schizophrenia globally. Schizophrenia affects about 20 million people worldwide, and with the growing global population, the number of cases is expected to rise. Additionally, the condition requires long-term treatment, which fosters sustained demand for effective medication options. Advances in medical science have led to the development of long-acting injectable antipsychotics, which improve patient adherence to treatment schedules by reducing the frequency of dosages needed compared to daily oral medications.



    Another contributing factor to the market's growth is the growing awareness and destigmatization of mental health issues. Governments and non-profit organizations worldwide have been actively working to improve mental health services and provide better support for individuals with mental health conditions. This has led to improved diagnosis rates and increased access to treatments, including medication. Furthermore, ongoing research and development activities continue to yield more effective and safer drug formulations, which are also expected to drive market growth.



    Additionally, the rise in healthcare expenditure and improvements in healthcare infrastructure in developing regions are expected to boost the market. As countries invest more in healthcare, they are better able to support the needs of patients with chronic conditions like schizophrenia. These investments lead to better access to advanced treatments and contribute to the overall growth of the market. Pharmaceutical companies are also increasingly focusing on emerging markets, which present significant growth opportunities due to their large patient populations and improving healthcare systems.



    On a regional level, North America dominates the long-acting schizophrenia drug market, accounting for the largest share in 2023. This is attributed to the high prevalence of schizophrenia, advanced healthcare infrastructure, and significant investments in research and development. Europe follows closely, with strong growth potential driven by similar factors. The Asia Pacific region is expected to witness the fastest growth over the forecast period, owing to increasing healthcare expenditure, rising awareness about mental health, and improving access to healthcare services. Latin America, and the Middle East & Africa are also anticipated to experience steady growth, although they currently hold smaller market shares compared to other regions.



    Drug Type Analysis



    The analysis of the market by drug type reveals two main categories: injectable and oral medications. Injectable long-acting antipsychotics have gained significant traction due to their ability to improve patient compliance and reduce the frequency of administration. These injectables are designed to maintain therapeutic drug levels over extended periods, typically ranging from weeks to months. This reduces the burden on patients to remember daily doses, which is particularly beneficial for those who struggle with adherence due to the cognitive impairments associated with schizophrenia.



    Injectable long-acting drugs also offer better control over the treatment process, as they ensure a more consistent delivery of medication. This consistency helps in managing symptoms more effectively and reducing the risk of relapse, which is crucial for improving the quality of life for patients. The market for injectable drugs is expected to grow at a robust rate, driven by these advantages and ongoing innovations in drug delivery systems.



    Oral long-acting medications, although less prominent than injectables, still hold a significant share of the market. These drugs are often preferred by patients who have a fear of needles or who prefer the convenience of oral administration. Advances in pharmaceutical formulations have led to the development of oral drugs that can provide sustained release of the active ingredient, thereby reducing the frequency of administration compared to traditional oral antipsychotics.



    &

  6. Anti Schizophrenic Drugs Market Report | Global Forecast From 2025 To 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Oct 5, 2024
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    Dataintelo (2024). Anti Schizophrenic Drugs Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/anti-schizophrenic-drugs-market
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    pdf, csv, pptxAvailable download formats
    Dataset updated
    Oct 5, 2024
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Anti Schizophrenic Drugs Market Outlook



    In 2023, the global market size for anti-schizophrenic drugs was estimated at approximately USD 14.2 billion. According to forecasts, this market is projected to reach around USD 22.9 billion by 2032, reflecting a compound annual growth rate (CAGR) of 5.5%. This growth is primarily driven by advancements in pharmaceutical research, increasing prevalence of schizophrenia, and rising awareness regarding mental health.



    One of the primary growth factors for the anti-schizophrenic drugs market is the advancement in pharmaceutical research and development. Innovations in drug formulations and delivery methods have significantly enhanced the efficacy and safety profiles of antipsychotic medications. The introduction of second-generation and third-generation antipsychotics has offered better symptom control with fewer side effects compared to first-generation antipsychotics, thereby increasing patient adherence and improving overall treatment outcomes. Moreover, the development of long-acting injectable formulations has provided a viable option for patients who have difficulty adhering to daily oral medication regimens.



    Another key growth driver is the increasing prevalence of schizophrenia and other related psychotic disorders. According to the World Health Organization, schizophrenia affects approximately 20 million people worldwide. The rising number of diagnosed cases, coupled with an aging population more prone to mental health disorders, is expected to boost the demand for effective antipsychotic treatments. Additionally, greater awareness and understanding of mental health issues are leading to more people seeking medical help, thereby driving up the prescription rates of antipsychotic medications.



    Government initiatives and supportive healthcare policies are also playing a crucial role in market growth. Many countries are implementing mental health programs and policies aimed at improving access to psychiatric care and medications. For instance, several governments are increasing healthcare funding and subsidies for mental health treatments, which in turn is facilitating broader access to antipsychotic drugs. Furthermore, the inclusion of these medications in national health insurance schemes is making treatment more affordable for patients, thereby driving market expansion.



    From a regional perspective, North America is expected to hold the largest market share in the anti-schizophrenic drugs market throughout the forecast period. This can be attributed to the high prevalence of schizophrenia, well-established healthcare infrastructure, and significant investment in research and development activities. Europe is also anticipated to experience substantial growth due to increasing awareness and government support for mental health initiatives. Meanwhile, the Asia Pacific region is projected to witness the fastest growth rate, driven by rising healthcare expenditure, improving access to medical services, and an increasing focus on mental health.



    Drug Class Analysis



    The anti-schizophrenic drugs market is segmented into three primary drug classes: first-generation antipsychotics, second-generation antipsychotics, and third-generation antipsychotics. First-generation antipsychotics, also known as typical antipsychotics, were the first class of drugs developed to treat schizophrenia and other psychotic disorders. These medications, such as haloperidol and chlorpromazine, primarily target dopamine receptors in the brain to alleviate psychotic symptoms. Despite their efficacy, first-generation antipsychotics are often associated with a higher incidence of side effects, including extrapyramidal symptoms and tardive dyskinesia.



    Second-generation antipsychotics, also known as atypical antipsychotics, represent a significant advancement over first-generation drugs. Introduced in the late 20th century, these medications, including risperidone, olanzapine, and quetiapine, offer a broader spectrum of action by targeting both dopamine and serotonin receptors. This dual mechanism of action not only improves symptom control but also reduces the likelihood of severe side effects. Consequently, second-generation antipsychotics have become the preferred treatment option for many patients and healthcare providers, contributing to their dominant market share.



    Third-generation antipsychotics are the latest class of drugs designed to treat schizophrenia. These medications, such as aripiprazole and brexpiprazole, utilize a novel mechanism of action by acting as partial agonists at dopamine receptors rather tha

  7. M

    Mental Health Clinical Trials Market Report

    • marketreportanalytics.com
    doc, pdf, ppt
    Updated May 5, 2025
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    Market Report Analytics (2025). Mental Health Clinical Trials Market Report [Dataset]. https://www.marketreportanalytics.com/reports/mental-health-clinical-trials-market-96496
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    pdf, ppt, docAvailable download formats
    Dataset updated
    May 5, 2025
    Dataset authored and provided by
    Market Report Analytics
    License

    https://www.marketreportanalytics.com/privacy-policyhttps://www.marketreportanalytics.com/privacy-policy

    Time period covered
    2025 - 2033
    Area covered
    Global
    Variables measured
    Market Size
    Description

    The global mental health clinical trials market is experiencing robust growth, projected to reach a substantial size with a Compound Annual Growth Rate (CAGR) of 8.11% from 2025 to 2033. This expansion is driven by several key factors. Firstly, the rising prevalence of mental health disorders like anxiety, depression, and schizophrenia globally fuels the demand for effective treatments, thereby increasing the number of clinical trials. Secondly, advancements in technology and research methodologies are leading to more sophisticated and efficient trial designs, accelerating the development and approval of new therapies. Furthermore, increased investments from pharmaceutical and biopharmaceutical companies, alongside government initiatives promoting mental health research, contribute significantly to market growth. The market is segmented by study design (interventional, observational), phase (I-IV), disorder (anxiety, depression, schizophrenia, etc.), and sponsor (pharmaceutical companies, government agencies). The North American region currently holds a significant market share due to advanced healthcare infrastructure and high research spending. However, Asia Pacific is anticipated to demonstrate strong growth in the coming years due to increasing awareness, rising disposable incomes, and expanding healthcare sectors in countries like China and India. The competitive landscape includes major players like IQVIA, Parexel, and Thermo Fisher Scientific, each contributing to innovation and competition within the market. The market's growth, however, faces certain restraints. High costs associated with clinical trials, lengthy regulatory approval processes, and the inherent complexity of mental health research pose challenges. Furthermore, difficulties in patient recruitment and retention for clinical trials, particularly those involving stigmatized conditions, can hinder progress. Despite these challenges, the ongoing unmet medical needs in mental health and the continuous innovation within the industry suggest a positive outlook for the market's long-term trajectory. The focus is shifting towards personalized medicine and innovative therapeutic approaches, which is expected to further stimulate market growth in the forecast period. The increasing adoption of digital technologies in clinical trials, such as telehealth and wearable sensors, is also streamlining processes and improving efficiency. Recent developments include: March 2024: MapLight Therapeutics Inc. initiated a Phase 1 clinical trial for ML-007/PAC, a novel extended-release fixed-dose combination therapy designed for the treatment of schizophrenia and Alzheimer's disease psychosis. This trial marks a critical advancement in developing targeted treatments for these complex central nervous system (CNS) disorders., February 2023: The Wellcome Trust granted USD 18.3 million to Oxford's Department of Psychiatry as part of its investment in mental health research for the Stratification & Treatment in Early Psychosis (STEP) program. The program would have 1,000 participants, including those with psychosis who have not responded to conventional treatment, others with first-episode psychosis, and those at clinically high risk for developing psychosis.. Key drivers for this market are: Rising Prevalence of Mental Health Conditions, Increasing Investment in Research and Development by Pharmaceutical and Biotech Companies. Potential restraints include: Rising Prevalence of Mental Health Conditions, Increasing Investment in Research and Development by Pharmaceutical and Biotech Companies. Notable trends are: The Phase III Clinical Trials Segment is Expected to Hold Significant Share in the Market During the Forecast Period.

  8. v

    Global Schizophrenia Drugs Market Size By Type (Paranoid Schizophrenia,...

    • verifiedmarketresearch.com
    Updated Aug 8, 2024
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    VERIFIED MARKET RESEARCH (2024). Global Schizophrenia Drugs Market Size By Type (Paranoid Schizophrenia, Hebephrenic Schizophrenia, Catatonic Schizophrenia and Undifferentiated Schizophrenia), By Treatment (Second-generation Antipsychotics, Third-generation Antipsychotics), By Route of Administration (Oral, Injectables), By Geographic Scope and Forecast [Dataset]. https://www.verifiedmarketresearch.com/product/schizophrenia-drugs-market/
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    Dataset updated
    Aug 8, 2024
    Dataset authored and provided by
    VERIFIED MARKET RESEARCH
    License

    https://www.verifiedmarketresearch.com/privacy-policy/https://www.verifiedmarketresearch.com/privacy-policy/

    Time period covered
    2024 - 2031
    Area covered
    Global
    Description

    Global Schizophrenia Drugs Market size was valued at USD 8.98 Billion in 2024 and is projected to reach 14.49 USD Billion by 2031 growing at a CAGR of 6.20% from 2024 to 2031.

    Global Schizophrenia Drugs Market Drivers The market drivers for the Schizophrenia Drugs Market can be influenced by various factors. These may include:

    Growing Prevalence of Schizophrenia: The market is being driven by the increasing incidence and prevalence of schizophrenia worldwide. The need for efficient medications to treat schizophrenia is growing as more people get the diagnosis.

    Developments in Drug Discovery: The market is being driven by ongoing research and development efforts to find new medications with higher efficacy and fewer negative effects. To improve patient outcomes, pharmaceutical companies are investing in novel drug formulations and delivery systems.

    Growing Awareness and Diagnosis: Early diagnosis and treatment initiation are being facilitated by greater public knowledge of mental health problems, such as schizophrenia, and by initiatives to lessen the stigma attached to mental illnesses. This pattern increases demand for medications for schizophrenia.

    Government Policies and Initiatives: Enhancing mental health services and treatment accessibility through government initiatives is a major factor propelling market expansion. The market is positively impacted by policies that increase financing for mental health services and broaden healthcare coverage.

    Technological Developments: New developments in diagnostics, like genetic testing and brain imaging methods, help us comprehend the fundamental causes of schizophrenia. This information promotes the creation of tailored treatments, which expands the market.

    Growing Senior Population: Schizophrenia primarily affects people in their late teens to early 30s, although instances are also seen in the elderly. The demand for medications specifically designed for older folks is predicted to rise as the world's population ages and the prevalence of schizophrenia among them rises.

    Growing Healthcare Expenditure: The acceptance of more sophisticated and costly schizophrenia drugs is facilitated by the general rise in healthcare spending, which is observed in both established and emerging markets. Increased market expansion is also facilitated by better access to healthcare services.

    Market Growth for Generic Drugs: The patents on a number of important medications for schizophrenia have expired, which has allowed generic versions to enter the market and raise accessibility and affordability. The market for generic drugs is growing, which supports the growth of the market as a whole.

    Pharmaceutical companies are placing a greater emphasis on patient-centric drug development in an effort to meet unmet requirements related to easier administration, better tolerability, and adherence. This strategy promotes market expansion and innovation.

    Partnerships and Collaborations: Partnerships and collaborations boost access to resources and speed up drug development efforts across advocacy organizations, research institutions, and pharmaceutical companies. Through the pooling of resources and knowledge made possible by strategic collaborations, more potent medications for schizophrenia can be developed.

  9. Schizophrenia Therapeutics Market Report | Global Forecast From 2025 To 2033...

    • dataintelo.com
    csv, pdf, pptx
    Updated Jan 7, 2025
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    Dataintelo (2025). Schizophrenia Therapeutics Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/global-schizophrenia-therapeutics-market
    Explore at:
    csv, pptx, pdfAvailable download formats
    Dataset updated
    Jan 7, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Schizophrenia Therapeutics Market Outlook



    In 2023, the global market size for schizophrenia therapeutics was valued at approximately USD 7.5 billion, with a projected growth at a compound annual growth rate (CAGR) of 4.2% over the forecast period from 2024 to 2032, leading to an estimated market size of around USD 10.5 billion by 2032. The increasing prevalence of schizophrenia, a chronic and severe mental disorder affecting over 20 million people globally, is one of the major factors driving market growth. Advances in drug development and treatment methodologies, combined with increased healthcare spending, are further contributing to the expansion of this market.



    The growing understanding of schizophrenia's complex etiology, which involves both genetic and environmental factors, has paved the way for more targeted therapies. Recent breakthroughs in neuroscience and psychopharmacology have enhanced the development of antipsychotics with improved efficacy and reduced side effects. These developments are crucial as they address the unmet needs of patients who are resistant to traditional medications or suffer from severe side effects. Furthermore, the integration of digital health technologies, such as telemedicine and electronic health records, has facilitated better patient management and adherence to treatment protocols, thus bolstering market growth.



    An increase in governmental and non-governmental funding for mental health research is also driving the market. Many countries have recognized mental health as a public health priority, leading to initiatives aimed at reducing the stigma surrounding mental illnesses and improving access to mental health services. This has resulted in a growing demand for effective schizophrenia treatments. In addition, collaborations between pharmaceutical companies and research institutions are fostering innovation and the development of novel therapeutics. Such partnerships are crucial in overcoming the high costs and lengthy timelines associated with drug development.



    The burgeoning geriatric population worldwide is another major growth factor for the schizophrenia therapeutics market. Aging populations are more susceptible to mental disorders, and as the number of elderly individuals rises, so does the incidence of schizophrenia in this demographic. This trend is particularly evident in developed regions such as North America and Europe, where healthcare infrastructure and awareness are robust. Additionally, lifestyle changes, urbanization, and increasing stress levels in modern societies are contributing to the rising cases of schizophrenia, which consequently propels the demand for its treatment solutions.



    Antipsychotic Medicine plays a pivotal role in the treatment of schizophrenia, serving as the primary therapeutic approach for managing the disorder's complex symptoms. These medications, particularly atypical antipsychotics, are designed to address both positive symptoms, such as hallucinations and delusions, and negative symptoms, like social withdrawal and lack of motivation. The evolution of antipsychotic medicine has been marked by the development of drugs with improved safety profiles and reduced side effects, which are crucial for enhancing patient adherence and quality of life. As research continues to advance, the focus remains on creating antipsychotic medicines that offer better efficacy with fewer adverse effects, ultimately aiming to provide more personalized treatment options for individuals with schizophrenia.



    Regionally, North America remains a prominent market for schizophrenia therapeutics, owing to its advanced healthcare system, high awareness, and substantial healthcare expenditure. Europe follows suit, driven by significant investments in mental health care and research. Meanwhile, the Asia Pacific region is expected to witness the fastest growth due to its large population base, increasing incidence of mental health disorders, and improving healthcare access. Countries like India and China are at the forefront of this growth, with expanding middle-class populations and increasing governmental focus on healthcare infrastructure. Latin America and the Middle East & Africa also present growth opportunities, albeit at a slower pace, due to socioeconomic factors and varying levels of healthcare development.



    Drug Class Analysis



    The drug class segment in the schizophrenia therapeutics market is pivotal, encompassing antipsychotics, antidepressants, antianxiety agents,

  10. Colombia: people treated for schizophrenia 2009-2018

    • statista.com
    Updated Jul 2, 2021
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    Statista (2021). Colombia: people treated for schizophrenia 2009-2018 [Dataset]. https://www.statista.com/statistics/970807/colombia-people-treated-schizophrenia/
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    Dataset updated
    Jul 2, 2021
    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    Colombia
    Description

    In 2018, a total of 81,988 people received treatment for schizophrenia in Colombia, around 28.6 percent more than in the year before. In 2017, the number of psychiatrists practicing in the South American country amounted to more than one thousand.

  11. f

    Data from: National and regional description of healthcare measures among...

    • tandf.figshare.com
    xlsx
    Updated May 31, 2023
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    Charmi Patel; Dominic Pilon; Deepshekhar Gupta; Laura Morrison; Marie-Hélène Lafeuille; Patrick Lefebvre; Carmela Benson (2023). National and regional description of healthcare measures among adult Medicaid beneficiaries with schizophrenia within the United States [Dataset]. http://doi.org/10.6084/m9.figshare.19915317.v1
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    xlsxAvailable download formats
    Dataset updated
    May 31, 2023
    Dataset provided by
    Taylor & Francis
    Authors
    Charmi Patel; Dominic Pilon; Deepshekhar Gupta; Laura Morrison; Marie-Hélène Lafeuille; Patrick Lefebvre; Carmela Benson
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Area covered
    United States
    Description

    Provide the first national description across the US of variations in healthcare measures in 2018 among Medicaid beneficiaries with schizophrenia. Adult beneficiaries with ≥2 diagnoses for schizophrenia, and continuous enrollment with consistent geographical data in all of 2018 were identified from Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files (TAF) data for 45 of 50 states. Antipsychotic (AP) utilization rates, including long-acting injectable APs (LAIs), quality metrics, and all-cause healthcare resource utilization and costs for claims submitted to Medicaid were reported nationally and by state. Pearson correlation evaluated associations between LAI utilization and total healthcare costs at state and county levels. Across the US 688,437 patients with schizophrenia were identified. The AP utilization rate was 51% (state range: 24–77%), while the LAI utilization rate was 13% (range: 4–26%). The proportion of patients adherent to any AP was 56% (range: 19–73%). Within 30 days post-discharge from an inpatient admission, 22% (range: 8–58%) of patients had an outpatient visit, and 12% (range: 4–48%) had a readmission. The proportion of patients with ≥1 inpatient admission and ≥1 emergency room visit was 34% (range: 19–82%) and 45% (range: 20–70%). Per-patient-per-year total healthcare costs averaged $32,920 (range: $717–$93,972). At the county level, a weak negative correlation was observed between LAI utilization and total healthcare costs. This study included Medicaid beneficiaries enrolled with pharmacy and medical benefits, including beneficiaries dually eligible for Medicare; results cannot be generalized to the overall schizophrenia population or those with other payer coverage. In 2018, half of beneficiaries with schizophrenia did not submit any claims for APs to Medicaid, nearly half had an emergency room visit, and one-third had an inpatient admission. Moreover, healthcare measures varied considerably across states. These findings may indicate unmet treatment needs for Medicaid beneficiaries with schizophrenia. Schizophrenia is a severe mental disorder that poses a large health, social, and cost burden to patients and society. While treatment with antipsychotic medications can reduce the number of relapses and hospitalizations, many patients do not adhere to treatment, which can lead to poor symptom control and further use of healthcare services. Interestingly, these measures of schizophrenia care seem to vary across US states. Therefore, we ran the first study to describe the regional differences in antipsychotic use, measures of quality of care, healthcare use, and healthcare costs among Medicaid-insured patients across the US in 2018. Our results showed that only half of patients used antipsychotics in 2018 (with a range of 24–77% across states) and the proportion of patients adherent to antipsychotic treatment was low (range of 19–73%). Additionally, nearly half of all patients had an emergency room visit (range of 20–70%), and one-third had an inpatient admission (range of 19–82%). These findings highlight large variations in antipsychotic use, performance measures, and healthcare use, possibly due to regional differences in unmet needs in schizophrenia care for Medicaid-insured patients in the US. Since use of inpatient and emergency room services was consistently high in specific states or regions, and yearly healthcare costs per patient varied from $717–$93,972 (mean = $32,920), there may be a particularly high burden in certain areas of the country where patients with schizophrenia may potentially be experiencing multiple relapses. Further research is needed to identify policies that may help narrow these regional differences.

  12. YLDs caused by schizophrenia in Latin America & the Caribbean 2019, by...

    • statista.com
    Updated Oct 27, 2023
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    Statista (2023). YLDs caused by schizophrenia in Latin America & the Caribbean 2019, by country [Dataset]. https://www.statista.com/statistics/1046564/latin-america-caribbean-years-lived-with-disability-schizophrenia/
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    Dataset updated
    Oct 27, 2023
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2019
    Area covered
    LAC, Latin America
    Description

    In 2019, Chile was the Latin American country with the highest number of years lived with disability (YLDs) due to schizophrenia per 100,00 people, with nearly 214 years of life lost due to this type of mental disorder. Uruguay and Argentina followed, with approximately 211 years and 210 years lived with disability (YLDs) caused by schizophrenia, or years lived with suboptimal health due to this condition. That year, nearly 249 years of healthy life were lost due to bipolar disorder in Brazil.

  13. o

    A scoping review of quality indicators for the measurement of schizophrenia...

    • osf.io
    url
    Updated Jun 22, 2022
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    Julia Kirkham; Jennifer Anderson (2022). A scoping review of quality indicators for the measurement of schizophrenia care [Dataset]. http://doi.org/10.17605/OSF.IO/5GUKP
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    urlAvailable download formats
    Dataset updated
    Jun 22, 2022
    Dataset provided by
    Center For Open Science
    Authors
    Julia Kirkham; Jennifer Anderson
    License

    Attribution-NonCommercial-NoDerivs 4.0 (CC BY-NC-ND 4.0)https://creativecommons.org/licenses/by-nc-nd/4.0/
    License information was derived automatically

    Description

    Treatment options for people affected by schizophrenia have improved considerably in the last 50 years, yet people affected by schizophrenia continue to experience poor mental and physical health outcomes. Despite well-established standards of care and interventions that can improve these outcomes, there is a substantial evidence to practice gap, and people affected by schizophrenia routinely receive poor quality healthcare.

    Quality of care (QoC) measurement in serious mental illness such as schizophrenia is increasing in importance and quality indicators (QIs) for the evaluation of schizophrenia care have been identified in Canada, the U.S., U.K. and elsewhere. Although various QIs have been established, there is no consensus on how best to measure schizophrenia quality of care and routine measurement of QIs in schizophrenia is not common. Among established QIs, many overlap. They are typically intended for use at the local, institutional level, whereas there is relatively little known about the measurement of population-based quality of schizophrenia care, which is essential to identifying large-scale quality concerns and opportunities for systems improvement.

    The guiding research questions are: 1) What are the quality indicators for the measurement of schizophrenia care?; 2) What are the major healthcare quality issues in schizophrenia? 3) What are the interventions that can improve QoC in schizophrenia?

  14. D

    Mental Disorder Treatment Market Report | Global Forecast From 2025 To 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Jan 7, 2025
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    Dataintelo (2025). Mental Disorder Treatment Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/mental-disorder-treatment-market
    Explore at:
    csv, pdf, pptxAvailable download formats
    Dataset updated
    Jan 7, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Mental Disorder Treatment Market Outlook



    The global mental disorder treatment market size was valued at approximately USD 64.8 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 6.3% from 2024 to 2032, reaching an estimated USD 113.5 billion by the end of the forecast period. Factors such as increasing awareness about mental health issues, rising prevalence of mental disorders, and advancements in treatment options are driving the market's growth.



    One of the primary growth factors for the mental disorder treatment market is the increasing awareness and reduction of stigma surrounding mental health issues. Over the past few years, numerous initiatives by governmental and non-governmental organizations have focused on educating the public about mental health, encouraging individuals to seek help, and normalizing conversations about mental disorders. This shift in societal perception has led to a higher rate of diagnosis and treatment, thereby expanding the market.



    Another significant driver is the rising prevalence of mental health disorders globally. According to the World Health Organization (WHO), mental health conditions are on the rise in every country in the world. Factors contributing to this include the high-stress levels associated with modern lifestyles, economic pressures, and the impact of social media. The increasing number of individuals experiencing anxiety, depression, and other mental health issues has created a pressing need for effective treatments, thus fueling market growth.



    Advancements in treatment options are also playing a crucial role in the expansion of the mental disorder treatment market. Innovations in medication, the development of novel psychotherapeutic approaches, and the advent of brain stimulation therapies have significantly improved treatment outcomes. Additionally, the integration of technology in treatment methods, such as telepsychiatry and mental health apps, has made mental health services more accessible and efficient, thereby contributing to market growth.



    Schizophrenia Treatments have seen significant advancements in recent years, contributing to the overall growth of the mental disorder treatment market. Schizophrenia, a complex psychotic disorder, requires a multifaceted approach to treatment, often involving a combination of medication, therapy, and support services. The development of atypical antipsychotics has been a game-changer, offering improved efficacy with fewer side effects compared to traditional medications. Furthermore, long-acting injectable formulations have enhanced treatment adherence, a critical factor in managing schizophrenia effectively. These innovations, alongside personalized treatment plans and community-based support, are pivotal in improving the quality of life for individuals living with schizophrenia, thereby driving demand in this market segment.



    Regionally, North America is the largest market for mental disorder treatments, driven by high healthcare spending, a well-established mental health infrastructure, and greater awareness among the population. Europe follows closely, with strong governmental support and robust healthcare systems. The Asia Pacific region, however, is expected to witness the highest growth rate during the forecast period due to increasing mental health awareness, economic development, and improving healthcare infrastructure.



    Disorder Type Analysis



    The mental disorder treatment market is segmented by disorder type into anxiety disorders, mood disorders, psychotic disorders, eating disorders, and others. Anxiety disorders represent a significant segment due to their high prevalence worldwide. Conditions such as generalized anxiety disorder, panic disorder, and social anxiety disorder affect millions of individuals. The treatment for anxiety disorders often includes a combination of medication, such as selective serotonin reuptake inhibitors (SSRIs), and cognitive-behavioral therapy (CBT), which has proven effective in managing symptoms.



    Mood disorders, including major depressive disorder and bipolar disorder, also constitute a substantial segment of the market. The growing incidence of depression, partly attributed to modern lifestyle stressors, has resulted in increased demand for effective treatments. Antidepressants, mood stabilizers, and psychotherapy are commonly used treatments. The introduction of esketamine nasal spray and other novel antidepressants has provi

  15. Percentage of U.S. college students with mental disorders in 2023-2024

    • statista.com
    • ai-chatbox.pro
    Updated Jun 20, 2025
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    Statista (2025). Percentage of U.S. college students with mental disorders in 2023-2024 [Dataset]. https://www.statista.com/statistics/1126287/percentage-of-college-students-with-mental-disorders-us/
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    Dataset updated
    Jun 20, 2025
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2023 - 2024
    Area covered
    United States
    Description

    A survey from 2023-2024 of college students in the United States found that the most common mental disorders that college students have been diagnosed with are anxiety disorders and depression or other mood disorders. Around ** percent of the college students surveyed at that time reported they had been diagnosed with an anxiety disorder at some point in their lifetime. Depression among college students Although college can be an exciting time, it can also be stressful and difficult. College students are often faced with new challenges related to living alone, their academic performance, the financial burden of attending college, and new social interactions. Therefore, anxiety and symptoms of depression are not uncommon among college students. In fact, it is estimated that up to ** percent of college students in the U.S. had symptoms of depression in 2023. Thankfully, depressive symptoms can usually be successfully treated through therapy, medication, lifestyle changes, or a combination of these. However, if left untreated depression can lead to thoughts of suicide or self-harm. A survey from 2023, found that up to ** percent of U.S. college students had thoughts of suicide in the past year. Mental health help on campus Many colleges in the United States have recognized the stress and anxiety that students can experience and now offer mental health resources on campus. However, barriers to access mental health services still exist. For example, as of 2024, around ** percent of surveyed college students in the U.S. indicated that they were not sure where on their campus to seek professional help for their mental or emotional health. Furthermore, around ** percent of students stated that they received fewer mental or emotional health services than they otherwise would have due to not having enough time for such services, while ** percent said they received fewer services due to financial reasons.

  16. Aripiprazole Drug Market Report | Global Forecast From 2025 To 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Sep 22, 2024
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    Dataintelo (2024). Aripiprazole Drug Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/global-aripiprazole-drug-market
    Explore at:
    pdf, pptx, csvAvailable download formats
    Dataset updated
    Sep 22, 2024
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Aripiprazole Drug Market Outlook




    The global aripiprazole drug market size was valued at USD 5.8 billion in 2023 and is projected to reach USD 9.4 billion by 2032, growing at a compounded annual growth rate (CAGR) of 5.5% during the forecast period. This growth is primarily driven by the rising prevalence of mental health disorders, advancements in pharmaceutical formulations, and increasing awareness about mental health treatment options.




    One of the significant growth factors for the aripiprazole drug market is the increasing prevalence of schizophrenia and bipolar disorder worldwide. These mental health conditions require long-term treatment and management, leading to sustained demand for aripiprazole. As the global population ages, the incidence of these psychiatric disorders is expected to rise, further propelling the market. Additionally, advancements in diagnostic tools and screening programs have made it easier to identify and treat these conditions early, contributing to the market's expansion.




    Another crucial driver for market growth is the continuous research and development activities aimed at improving drug formulations and delivery methods. Pharmaceutical companies are investing heavily in creating more effective and convenient forms of aripiprazole, such as orally disintegrating tablets and long-acting injectable formulations. These innovations improve patient compliance and treatment outcomes, thereby boosting market demand. The increasing focus on personalized medicine and targeted therapies also plays a significant role in market growth, as these approaches enhance the efficacy and safety of aripiprazole treatments.




    Rising awareness about mental health issues and the availability of effective treatments is also contributing to the market's growth. Governments and non-profit organizations worldwide are launching campaigns to destigmatize mental health conditions and encourage people to seek help. These initiatives are increasing the number of people undergoing treatment for disorders like schizophrenia and bipolar disorder, thereby driving the demand for aripiprazole. Furthermore, the growing integration of mental health services into primary healthcare systems is making it easier for patients to access necessary medications, including aripiprazole.




    The regional outlook for the aripiprazole drug market is also promising, with North America and Europe leading in terms of market share due to advanced healthcare infrastructure and high awareness levels. However, emerging markets in the Asia Pacific and Latin America are expected to exhibit significant growth rates due to increasing healthcare expenditure and expanding access to mental health services. For instance, countries like China and India are witnessing a rise in mental health awareness, leading to higher demand for effective treatments, including aripiprazole.



    Dosage Form Analysis




    The dosage form of a drug plays a critical role in its efficacy and patient compliance. In the aripiprazole drug market, various dosage forms are available, including tablets, orally disintegrating tablets, oral solutions, and injections. Tablets are the most commonly used form due to their convenience, ease of administration, and cost-effectiveness. They are particularly popular among patients who require daily medication for managing chronic conditions like schizophrenia and bipolar disorder. The widespread availability of tablets in hospital and retail pharmacies also contributes to their dominance in the market.




    Orally disintegrating tablets are gaining traction due to their ease of use, especially among patients who have difficulty swallowing traditional tablets. These tablets dissolve quickly in the mouth, making them an excellent option for children, elderly patients, and those with swallowing difficulties. The increased focus on patient-centric formulations is driving the growth of this segment. Additionally, orally disintegrating tablets offer the advantage of rapid onset of action, which can be beneficial in acute settings where quick symptom relief is required.




    Oral solutions are another important dosage form in the aripiprazole market. They offer flexibility in dosing, which is particularly useful for pediatric and geriatric populations who may require non-standard doses. Oral solutions are also easier to administer to patients with dysphagia or other swallowing difficulties. Ho

  17. Epidemiologic Catchment Area (ECA) Survey of Mental Disorders, Wave I...

    • icpsr.umich.edu
    • explore.openaire.eu
    ascii, sas, spss
    Updated Jun 3, 1994
    + more versions
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    United States Department of Health and Human Services. National Institute of Mental Health (1994). Epidemiologic Catchment Area (ECA) Survey of Mental Disorders, Wave I (Household), 1980-1985: [United States] [Dataset]. http://doi.org/10.3886/ICPSR08993.v1
    Explore at:
    sas, spss, asciiAvailable download formats
    Dataset updated
    Jun 3, 1994
    Dataset provided by
    Inter-university Consortium for Political and Social Researchhttps://www.icpsr.umich.edu/web/pages/
    Authors
    United States Department of Health and Human Services. National Institute of Mental Health
    License

    https://www.icpsr.umich.edu/web/ICPSR/studies/8993/termshttps://www.icpsr.umich.edu/web/ICPSR/studies/8993/terms

    Time period covered
    1980 - 1985
    Area covered
    United States
    Description

    The Epidemiologic Catchment Area (ECA) program of research was initiated in response to the 1977 report of the President's Commission on Mental Health. The purpose was to collect data on the prevalence and incidence of mental disorders and on the use of and need for services by the mentally ill. The ECA Survey is the largest and most comprehensive survey of mental disorders ever conducted in the United States. The scope and complexity of the survey design were made possible because of the confluence of the recent standardization of psychiatric diagnostic criteria and the availability of advanced computer data processing systems. Independent research teams at five universities (Yale, Johns Hopkins, Washington University, Duke University, and University of California at Los Angeles), in collaboration with NIMH, conducted the studies with a core of common questions and sample characteristics. The sites were areas that had previously been designated as Community Mental Health Center catchment areas (New Haven, CN, Baltimore, MD, St. Louis, MO, Durham, NC, and Los Angeles, CA). The ECA encompassed a Household Survey and an Institutional Survey at each site, with two waves of personal interviews administered one year apart and a brief telephone interview in between. The structured psychiatric diagnostic interview used in the ECA was the NIMH Diagnostic Interview Schedule (DIS), version III (with the exception of the Yale Wave I survey, which used version II). Diagnostic and Statistical Manual of Mental Disorders, 3rd edition (DSM-III) diagnoses derived from the DIS include manic episode, major depressive episode, dysthymia, bipolar disorder, alcohol abuse or dependence, drug abuse or dependence, schizophrenia, schizophreniform, obsessive compulsive disorder, phobia, somatization, panic, antisocial personality, and anorexia nervosa. The DIS elicits diagnoses across the respondent's full life span and also indicates when symptoms appeared during the last year (within last two weeks, last month, last six months, and last full year). The DIS uses the Mini-Mental State Examination to screen, when respondents appear confused, for cognitive impairment and inability to complete the interview, and continuation by a proxy interview.

  18. Iloperidone Drugs Market Report | Global Forecast From 2025 To 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Jan 7, 2025
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    Dataintelo (2025). Iloperidone Drugs Market Report | Global Forecast From 2025 To 2033 [Dataset]. https://dataintelo.com/report/iloperidone-drugs-market
    Explore at:
    csv, pdf, pptxAvailable download formats
    Dataset updated
    Jan 7, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Iloperidone Drugs Market Outlook



    The global iloperidone drugs market size was valued at approximately USD 1.2 billion in 2023 and is projected to reach around USD 2.3 billion by 2032, growing at a CAGR of 7% during the forecast period. The growth of the iloperidone drugs market is driven by the increasing prevalence of schizophrenia and bipolar disorder, coupled with advancements in pharmaceutical formulations and rising awareness about mental health conditions.



    One of the key growth factors for the iloperidone drugs market is the rising prevalence of mental health disorders worldwide. The increasing incidence of schizophrenia and bipolar disorder, conditions that iloperidone is specifically prescribed for, is driving the demand for effective treatment options. According to the World Health Organization, approximately 20 million people globally suffer from schizophrenia, and the prevalence of bipolar disorder is also rising. This creates a substantial market for iloperidone, a second-generation antipsychotic known for its efficacy and favorable side effect profile.



    Another significant growth driver is the continuous advancements in pharmaceutical formulations. The development of more efficient and patient-friendly dosage forms, such as extended-release tablets and improved capsule formulations, enhances patient compliance and treatment outcomes. Pharmaceutical companies are investing heavily in research and development to innovate and improve iloperidone formulations, which is expected to further propel market growth. Additionally, the increasing availability of generic versions of iloperidone makes the drug more accessible and affordable to a wider patient population.



    Furthermore, the growing awareness and acceptance of mental health treatment are contributing to market expansion. Governments and healthcare organizations worldwide are launching initiatives to reduce the stigma associated with mental health conditions and promote early diagnosis and treatment. This shift in societal attitudes is encouraging more individuals to seek help for mental health issues, thereby increasing the demand for effective medications like iloperidone. The expansion of healthcare infrastructure and the growing number of mental health professionals are also supporting market growth by improving access to treatment.



    Risperidone, another second-generation antipsychotic, shares similarities with iloperidone in terms of its application for mental health disorders. It is widely used in the treatment of schizophrenia and bipolar disorder, offering an alternative for patients who may not respond well to iloperidone. The availability of multiple antipsychotic options like risperidone allows healthcare providers to tailor treatment plans to individual patient needs, enhancing the likelihood of achieving optimal therapeutic outcomes. As with iloperidone, the development of risperidone has been driven by the need for effective medications with manageable side effect profiles, contributing to its widespread acceptance in psychiatric care.



    From a regional perspective, North America holds a significant share of the iloperidone drugs market, driven by a high prevalence of mental health disorders, advanced healthcare infrastructure, and robust pharmaceutical research and development activities. Europe follows closely, with substantial market contributions from countries like Germany, France, and the UK. The Asia Pacific region is expected to exhibit the highest growth rate during the forecast period, attributed to increasing healthcare expenditure, rising awareness about mental health, and improving access to healthcare services.



    Dosage Form Analysis



    The iloperidone drugs market is segmented by dosage form into tablets, capsules, and others. Tablets represent a significant portion of the market due to their ease of administration and widespread acceptance among patients and healthcare providers. Tablets offer precise dosing, which is crucial for managing mental health conditions that require strict adherence to medication regimens. The development of extended-release tablets has further enhanced patient compliance by reducing the frequency of dosing, addressing one of the common challenges in long-term mental health treatment.



    Capsules, another important segment, are also gaining traction due to their advantages in terms of bioavailability and patient preference. Many patients find capsules easier to swallow than tablets, which can improve m

  19. Mental health treatment facilities by setting of services in the U.S. 2023

    • statista.com
    • ai-chatbox.pro
    Updated Dec 4, 2024
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    Statista (2024). Mental health treatment facilities by setting of services in the U.S. 2023 [Dataset]. https://www.statista.com/statistics/450277/mental-health-facilities-in-the-us-by-service-type/
    Explore at:
    Dataset updated
    Dec 4, 2024
    Dataset authored and provided by
    Statistahttp://statista.com/
    Time period covered
    2023
    Area covered
    United States
    Description

    Mental health treatment facilities are instrumental in helping those suffering from acute or chronic mental health issues get care in a safe and secure environment. As of 2023, there were 12,012 mental health treatment facilities in the U.S., of which 9,856 completed the N-SUMHSS* survey. Within those, 8,270 were outpatient facilities while 1,184 facilities were hospital inpatient facilities. U.S. Mental health facilities Inpatient mental health treatment may be needed for those that are a danger to themselves or others, those using drugs, those that need to be stabilized or those that are experiencing psychosis. The top hospitals in the U.S. for adult psychiatry include McLean Hospital in Massachusetts and Massachusetts General Hospital. Few mental health treatment facilities offered treatment programs specific client groups, with just a third offering such to LGBTQ clients. Mental health in the U.S. Mental illness can affect anyone of any age; however, some groups experience more mental illness than others. It is estimated that up to one quarter of the U.S. adult population face some mental illness, with women suffering more than men. A recent survey also demonstrated that Utah, Oregon, and District of Columbia had the highest percentage of people that described their mental health as poor. Other mental health variables can compound one another. For example, mental illness and substance use can be especially difficult to diagnose and treat.

  20. Social Cognitive Role of Schizophrenia Candidate Gene GABRB2

    • plos.figshare.com
    tiff
    Updated May 30, 2023
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    Shui Ying Tsang; Songfa Zhong; Lingling Mei; Jianhuan Chen; Siu-Kin Ng; Frank W. Pun; Cunyou Zhao; Bingyi Jing; Robin Chark; Jianhua Guo; Yunlong Tan; Lijun Li; Chuanyue Wang; Soo Hong Chew; Hong Xue (2023). Social Cognitive Role of Schizophrenia Candidate Gene GABRB2 [Dataset]. http://doi.org/10.1371/journal.pone.0062322
    Explore at:
    tiffAvailable download formats
    Dataset updated
    May 30, 2023
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Shui Ying Tsang; Songfa Zhong; Lingling Mei; Jianhuan Chen; Siu-Kin Ng; Frank W. Pun; Cunyou Zhao; Bingyi Jing; Robin Chark; Jianhua Guo; Yunlong Tan; Lijun Li; Chuanyue Wang; Soo Hong Chew; Hong Xue
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    The occurrence of positive selection in schizophrenia-associated GABRB2 suggests a broader impact of the gene product on population fitness. The present study considered the possibility of cognition-related GABRB2 involvement by examining the association of GABRB2 with psychosis and altruism, respectively representing psychiatric and psychological facets of social cognition. Four single nucleotide polymorphisms (SNPs) were genotyped for quantitative trait analyses and population-based association studies. Psychosis was measured by either the Positive and Negative Syndrome Scale (PANSS) or antipsychotics dosage, and altruism was based on a self-report altruism scale. The minor alleles of SNPs rs6556547, rs1816071 and rs187269 in GABRB2 were correlated with high PANSS score for positive symptoms in a Han Chinese schizophrenic cohort, whereas those of rs1816071 and rs1816072 were associated with high antipsychotics dosage in a US Caucasian schizophrenic cohort. Moreover, strongly significant GABRB2-disease associations were found among schizophrenics with severe psychosis based on high PANSS positive score, but no significant association was observed for schizophrenics with only mild psychosis. Interestingly, in addition to association with psychosis in schizophrenics, rs187269 was also associated with altruism in healthy Han Chinese. Furthermore, parallel to correlation with severe psychosis, its minor allele was correlated with high altruism scores. These findings revealed that GABRB2 is associated with psychosis, the core symptom and an endophenotype of schizophrenia. Importantly, the association was found across the breadth of the psychiatric (psychosis) to psychological (altruism) spectrum of social cognition suggesting GABRB2 involvement in human cognition.

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Statista (2023). Share of the U.S. population with schizophrenia from 1990 to 2019 [Dataset]. https://www.statista.com/statistics/981206/schizophrenia-us-share-of-population/
Organization logo

Share of the U.S. population with schizophrenia from 1990 to 2019

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Dataset updated
Nov 29, 2023
Dataset authored and provided by
Statistahttp://statista.com/
Area covered
United States
Description

This statistic depicts the share of the U.S. population who suffered from schizophrenia from 1990 to 2019. As of 2019, around 0.47 percent of the population had schizophrenia.

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