This statistic shows the number of registrations of newly diagnosed cases of ovarian cancer in England in 2022, by age group. The most affected age group was among 75 to 79 year olds, with 908 cases reported in 2022.
This statistic shows the rate of registrations of newly diagnosed cases of ovarian cancer per 100,000 population in England in 2020, by region. With a rate of 22.4 newly diagnosed females with ovarian cancer per 100,000 population in 2020, the regions most affected by ovarian cancer was North West.
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ObjectivesIt is important to assess the burden of ovarian cancer related premature death so as to develop appropriate evidence-based care and improve women’s health. This study aimed to characterize the long-term trends in mortality, survival and disease burden of ovarian cancer in Shanghai, China.Materials and MethodsCo-morbidities, crude mortality rate (CMR), age-standardised mortality rate by Segi’s world standard population (ASMRW), years of life lost (YLL), and survival rates were analysed. Temporal trends for the mortality rates and disease burden were analyzed using the Joinpoint Regression Program. Mortality rate increases by demographic and non-demographic factors were estimated by the decomposition method.ResultsA total of 1088 ovarian cancer as underlying cause of deaths were recorded. CMR and ASMRW were 4.82/105 and 2.32/105 person-years, respectively. The YLL was 16372.96 years, and the YLL rate was 72.46/105 person-years. The YLL rate increased only in the age group of 70-79 years (P = 0.017). The survival rates of ovarian cancer patients did not improve during the ten year period (2005-2015). The top co-morbidities were diseases of the respiratory system, digestive system, and circulatory system. The rates of ovarian cancer deaths caused by non-demographic and demographic factors increased by 21.29% (95%CI: 4.01% to 41.44%, P = 0.018) and 25.23% (95%CI: 14.64% to 36.81%, P < 0.001), respectively.ConclusionsPopulation ageing and all cause of death may affect ovarian cancer related deaths in Pudong, Shanghai. The high mortality and the stagnant survival rates suggest the need for more efforts in targeted prevention and treatment of this disease.
This statistic shows the five-year survival rate for ovarian cancer cases among U.S. women from 2008 to 2014, by stage at diagnosis. According to the data, 92 percent of women that are diagnosed with a localized stage of ovarian cancer will survive five years after their diagnosis.
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O objetivo é analisar o efeito da idade, período e coorte (APC) na mortalidade por câncer de ovário nas regiões Sul e Nordeste do Brasil. Os modelos APC foram estimados por regressão de Poisson por meio de funções estimáveis em mulheres com 30 anos ou mais residentes nos estados das regiões Sul e Nordeste. Estimados os modelos APC, verificou-se aumento nas taxas de mortalidade com o avançar da idade em todas as localidades. A região Sul apresentou redução do risco de morte nos dois últimos períodos (RR2010-2014 0,94; RR2015-2019 0,90, p<0,001) e redução do risco nas coortes de 1900 a 1929 (RR1900-04 0,55, RR1925-1929 0,89, p<0,001); perfil semelhante foi observado em todos os estados. No Nordeste, houve aumento progressivo do risco de morte nos últimos períodos, variando de 1,02 a 1,11 (2010-2014 vs. 2015-2019, p<0,001). E aumento do risco de morte nas coortes mais jovens, variando de 0,31 a 1,54 (1900-1904 vs. 1985-1989). Resultados semelhantes foram observados na maioria de seus estados isso pode estar correlacionado com os diferentes ritmos do processo de envelhecimento populacional e com as mudanças no comportamento reprodutivo das mulheres dessas duas regiões, realidade intrinsecamente ligada ao desenvolvimento socioeconômico e ao acesso aos serviços de saúde. The scope of this study was to conduct an analysis on the effect of the Age-Period-Cohort (APC) on ovarian cancer mortality in the South and Northeast regions of Brazil. The APC models were estimated by Poisson regression through estimable functions in women aged 30 and over residing in the states of the South and Northeast regions. Upon estimating the APC models, a positive gradient was found in mortality rates with advancing age in all locations The South region showed a reduction in the risk of death in the last two periods (RR2010-2014 0.94; RR2015-2019 0.90, p<0.001) and a reduction in risk in the cohorts from 1900 to 1929 (RR1900-04 0.55, RR1925-1929 0.89, p<0.001); a similar profile was observed in all states. In the Northeast, there was a progressive increase in the risk of death in the last periods, ranging from 1.02 to 1.11 (2010-2014 vs. 2015-2019, p<0.001). An increased risk of death was observed in younger cohorts, varying from 0.31 to 1.54 (cohort 1900-1904 vs. 1985-1989). Similar results were observed in most of the states.: The conclusion drawn is that heterogeneity in the APC effect on ovarian cancer mortality, which may be correlated with the different rates of the population aging process, changes in the reproductive behavior of women, and inequalities in access to health services. El objetivo es analizar el efecto de la edad, período y cohorte (EPC) sobre la mortalidad por cáncer de ovario en las regiones Sur y Nordeste de Brasil. Se estimaron modelos EPC mediante regresión de Poisson utilizando funciones estimables en mujeres de 30 años o más residentes en los estados de las regiones Sur y Nordeste. Luego de estimar los modelos EPC, se observó un aumento en las tasas de mortalidad con el avance de la edad en todas las localidades. La región Sur mostró una reducción del riesgo de muerte en los dos últimos periodos (RR2010-2014 0,94; RR2015-2019 0,90, p<0,001) y una reducción del riesgo en las cohortes de 1900 a 1929 (RR1900-04 0,55; RR1925-1929 0,89, p<0,001); Se observó un perfil similar en todos los estados. En el Nordeste, se observó un aumento progresivo del riesgo de muerte en los últimos períodos, variando de 1,02 a 1,11 (2010-2014 vs. 2015-2019, p<0,001). Y un mayor riesgo de muerte en cohortes más jóvenes, que oscila entre 0,31 y 1,54 (1900-1904 frente a 1985-1989). Resultados similares se observaron en la mayoría de sus estados, lo que puede estar correlacionado con las diferentes tasas del proceso de envejecimiento poblacional y con los cambios en el comportamiento reproductivo de las mujeres en estas dos regiones, realidad intrínsecamente ligada al desarrollo socioeconómico y al acceso a los servicios de salud. Supplementary Material Table 1. Characterization of states in the South and Northeast regions according to sociodemographic variables, health indicators and access to health services, Brazil. Supplementary Material Table S2. Analysis of the Akaike Information Criterion (AIC) in the sequential construction of age, period and cohort models for ovarian cancer fitting by estimable functions, Northeast and South, Brazil, 1980-2019. Supplementary Material Table 1. Characterization of states in the South and Northeast regions according to sociodemographic variables, health indicators and access to health services, Brazil. Supplementary Material Table S2. Analysis of the Akaike Information Criterion (AIC) in the sequential construction of age, period and cohort models for ovarian cancer fitting by estimable functions, Northeast and South, Brazil, 1980-2019. Supplementary Material Table 1. Characterization of states in the South and Northeast regions according to sociodemographic variables, health indicators and...
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IntroductionOvarian cancer is one of the most lethal gynecological cancers. Despite diagnosis and treatment advances, survival rates have not increased over the past 32 years. This study estimated and reported the global burden of ovarian cancer during the past 32 years to inform preventative and control strategies.MethodsWe examined ovarian cancer incidence, mortality, and disability-adjusted life years (DALYs) using age-standardized rates from the Global Burden of Disease, Injuries, and Risk Factors Study 2021. high body mass index and occupational asbestos exposure were linked with death and DALYs. Data are presented as averages with 95% uncertainty intervals (UIs).ResultsIndonesia had 13 250 (8 574–21 565) ovarian cancer cases in 2021, with 5 296 (3 520–8958) deaths and 186 917 (121 866–309 820) DALYs. The burden increased by 233.53% for new cases, 221.95% for mortalities, and 206.65% for DALYs. The age-standardized rate also increased from 1990 to 2021. Ovarian cancer burden increased with age but declined in the 50+ year age group. According to the sociodemographic index, the gross domestic product per capita and number of obstetricians and oncologic gynecologists in provinces showed different trends.ConclusionsIndonesian ovarian cancer rates are rising despite gynecologic oncologists in 24 of 34 provinces. These findings will help policymakers and healthcare providers identify ovarian cancer prevention and control gaps.
This statistic shows the number of deaths due to ovary cancer in the United States from 1999 to 2021. The highest number of deaths due to ovary cancer was reported for 2006, with almost ****** deaths.
In 2021, more than ****** new cases of ovarian cancer were recorded in China. The prevalence of the disease is expected to grow even further, exceeding ****** cases in 2026. Ovarian cancer is one of the most common cancers among women. In its early stages, there may be few symptoms, making early diagnosis relatively difficult.
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According to Cognitive Market Research, the global ovarian cancer market size is USD 1751.2 million in 2024 and will expand at a compound annual growth rate (CAGR) of 24.30% from 2024 to 2031.
North America held the major market of around 40% of the global revenue with a market size of USD 700.48 million in 2024 and will grow at a compound annual growth rate (CAGR) of 22.5% from 2024 to 2031.
Europe accounted for a share of over 30% of the global market size of USD 525.36 million.
Asia Pacific held the market of around 23% of the global revenue with a market size of USD 402.78 million in 2024 and will grow at a compound annual growth rate (CAGR) of 26.3% from 2024 to 2031.
Latin America market of around 5% of the global revenue with a market size of USD 87.56 million in 2024 and will grow at a compound annual growth rate (CAGR) of 23.7% from 2024 to 2031.
Middle East and Africa held the major market of around 2% of the global revenue with a market size of USD 35.02 million in 2024 and will grow at a compound annual growth rate (CAGR) of 24.0% from 2024 to 2031.
The targeted therapy held the highest growth rate in ovarian cancer market in 2024.
Market Dynamics of Ovarian Cancer Market
Key Drivers of Ovarian Cancer Market
Rising Incidence of Ovarian Cancer Globally to Increase the Global Demand
The rising global incidence of ovarian cancer is a significant driver amplifying demand within the market. Ovarian cancer ranks among the most prevalent gynaecological malignancies worldwide, with incidence rates steadily climbing. Factors such as aging populations, lifestyle changes, genetic predispositions, and environmental factors contribute to this uptrend. As more cases emerge, there is a heightened need for comprehensive screening, accurate diagnosis, and effective treatment options. This surge in demand extends across various segments of the ovarian cancer market, including diagnostic imaging, pharmaceuticals, and therapeutic interventions. Healthcare providers are under pressure to meet the escalating demand for services, driving investments in infrastructure, research, and innovation. Additionally, governmental and non-governmental initiatives focused on raising awareness and improving access to healthcare further bolster the market's growth trajectory amidst this concerning trend.
For instance, according to the American Cancer Society, more than 19,880 women in the United States are expected to be diagnosed with ovarian cancer in 2021.
(Source:https://www.cancer.org/cancer/types/ovarian-cancer/about/key-statistics.html )
Technological Advancements in Diagnostic Imaging to Propel the Growth
Technological advancements in diagnostic imaging are poised to revolutionize the landscape of ovarian cancer detection and management, driving substantial market growth. Innovations such as high-resolution ultrasound, magnetic resonance imaging (MRI), and positron emission tomography (PET) scans offer enhanced visualization and accuracy in detecting ovarian tumours, leading to earlier diagnosis and improved patient outcomes. Moreover, developments in molecular imaging techniques enable clinicians to identify specific biomarkers associated with ovarian cancer, facilitating personalized treatment strategies. Artificial intelligence (AI) and machine learning algorithms further augment diagnostic capabilities by analyzing complex imaging data, aiding in the early detection and precise characterization of ovarian lesions. As healthcare providers increasingly adopt these cutting-edge imaging technologies, the demand for advanced diagnostic equipment and services is expected to soar, propelling significant growth opportunities in the ovarian cancer market while improving patient care and prognosis. • For instance, Imunon has announced the commencement of subject enrolment at Memorial Sloan Kettering Center Center in Phase I/II clinical trial for DNA-based interleukin-12 immunotherapy IMNN-001, in patients with advanced ovarian cancer. https://www.clinicaltrialsarena.com/news/imunon-ovarian-cancer-trial/ (Source:https://www.clinicaltrialsarena.com/news/imunon-ovarian-cancer-trial/ )
• For instance, Avastin is a precision cancer medicine that targets a protein known as VEGF. VEGF plays a key role in the development of new blood vessels necessary for cancer cell growth. By blocking VEGF, Avasti...
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Ovarian cancer is one of the most lethal gynecological cancers. Despite diagnosis and treatment advances, survival rates have not increased over the past 32 years. This study estimated and reported the global burden of ovarian cancer during the past 32 years to inform preventative and control strategies. We examined ovarian cancer incidence, mortality, and disability-adjusted life years (DALYs) using age-standardized rates from the Global Burden of Disease, Injuries, and Risk Factors Study 2021. high body mass index and occupational asbestos exposure were linked with death and DALYs. Data are presented as averages with 95 % uncertainty intervals (UIs). Indonesia had 13 250 (8 574–21 565) ovarian cancer cases in 2021, with 5 296 (3 520–8958) deaths and 186 917 (121 866–309 820) DALYs. The burden increased by 233.53 % for new cases, 221.95 % for mortalities, and 206.65 % for DALYs. The age-standardized rate also increased from 1990 to 2021. Ovarian cancer burden increased with age but declined in the 50+ year age group. According to the sociodemographic index, the gross domestic product per capita and number of obstetricians and oncologic gynecologists in provinces showed different trends. Indonesian ovarian cancer rates are rising despite gynecologic oncologists in 24 of 34 provinces. These findings will help policymakers and healthcare providers identify ovarian cancer prevention and control gaps.
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Ovarian cancer incidence, mortality, and DALYs by provincial level in Indonesia, 1990–2021.
This statistic shows the distribution of major types of ovarian cancer among different ethnicities from 2010 to 2014. According to the data, among all races, ** percent of ovarian cancer cases are epithelial ovarian cancer, compared to just * percent of ovarian cancer cases that are sex cord-stromal ovarian cancer.
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The global ovarian cancer market size was estimated to be USD 3.5 billion in 2023, with a projected compound annual growth rate (CAGR) of 7.2% from 2024 to 2032. This robust growth is driven by several factors, including advancements in medical technology, increasing awareness about early diagnosis, and the rising prevalence of ovarian cancer worldwide. By 2032, the market is expected to reach approximately USD 6.5 billion, underscoring the critical need for innovative treatment strategies and accessible healthcare solutions across various regions. Such growth is largely attributed to increasing investments in research and development, leading to novel therapeutic options and the expansion of healthcare infrastructure globally.
One of the significant growth factors for the ovarian cancer market is the increasing incidence and prevalence of the disease. Ovarian cancer remains one of the leading causes of cancer-related deaths among women, primarily due to late diagnosis. Early-stage ovarian cancer often presents with nonspecific symptoms, resulting in late-stage detection when treatment options are limited. This challenge has prompted greater focus on developing better diagnostic tools and screening methods, which is expected to drive market growth. Additionally, lifestyle factors, genetic predispositions, and increasing age are contributing to the rising incidence rates, further scaling the demand for effective treatment solutions.
The advent of precision medicine is another pivotal factor propelling the growth of the ovarian cancer market. Precision medicine involves tailoring healthcare treatments to individual patients based on genetic, environmental, and lifestyle factors. This approach is gaining traction as it promises to improve treatment efficacy and patient outcomes. The development of targeted therapies, which aim to attack specific cancer cells while sparing healthy ones, represents a significant advancement. These therapies are becoming increasingly integrated into standard treatment protocols, supported by favorable clinical outcomes and regulatory approvals. As a result, the market is witnessing an influx of targeted therapy options, offering renewed hope for patients and driving market expansion.
Increasing awareness and advocacy efforts are also playing a crucial role in the growth of the ovarian cancer market. Various organizations and stakeholders are actively involved in raising awareness about ovarian cancer symptoms, risk factors, and the importance of regular medical check-ups. Such initiatives have led to greater patient education and improved healthcare-seeking behaviors, contributing to earlier diagnoses and better management of the disease. Additionally, governmental and non-governmental funding for ovarian cancer research is bolstering the market by facilitating the development of new drugs and treatment methodologies. These collaborative efforts are poised to sustain the market's growth trajectory in the coming years.
The development and availability of Gynaecological Cancer Drugs are pivotal in addressing the treatment needs of ovarian cancer patients. These drugs are specifically designed to target the unique biological characteristics of gynecological cancers, including ovarian cancer, providing more effective and tailored treatment options. The innovation in this field is driven by extensive research and development efforts, focusing on improving drug efficacy and minimizing side effects. As a result, patients have access to a broader range of therapeutic options, enhancing their chances of successful treatment outcomes. The integration of these drugs into standard treatment protocols is supported by clinical evidence demonstrating their benefits in managing ovarian cancer. As the market for gynaecological cancer drugs continues to expand, it is expected to play a significant role in the overall growth of the ovarian cancer treatment landscape.
Regionally, North America dominates the ovarian cancer market, owing to its well-established healthcare infrastructure, high prevalence of the disease, and extensive research activities. The presence of leading pharmaceutical companies and research institutions further supports market growth in this region. Europe follows closely, with countries like Germany, France, and the UK making substantial investments in cancer research and treatment. The Asia Pacific region is expected to witness the fastest growth rate, driven by increasing healthcare awareness and improving healthcare infrastructure. Rapid urbanization and e
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The global ovarian cancer diagnostics and therapeutics market size was valued at approximately USD 2.6 billion in 2023 and is projected to reach USD 5.5 billion by 2032, registering a compound annual growth rate (CAGR) of 8.5% during the forecast period. The growth in this market is primarily driven by advancements in medical technology, increased awareness about cancer diagnosis and treatment options, and the rising prevalence of ovarian cancer worldwide. With improved diagnostic methodologies and an expanding portfolio of therapeutic options, the market is poised for significant progress over the next decade.
One of the primary growth factors for the ovarian cancer diagnostics and therapeutics market is the increasing global incidence of ovarian cancer. Ovarian cancer is one of the leading causes of cancer deaths among women, and its growing prevalence is a critical factor necessitating the development and implementation of advanced diagnostic and therapeutic solutions. The aging population, especially in developed regions, is also contributing to the rising incidence rates, as ovarian cancer risk significantly increases with age. Moreover, lifestyle changes and genetic predispositions are further exacerbating the potential for increased cases, thereby fueling market demand for effective diagnostic tools and therapeutic options.
Another significant growth factor is the technological advancements in the field of cancer diagnostics and treatment. Breakthroughs in imaging technologies, molecular diagnostics, and personalized medicine have revolutionized how ovarian cancer is detected and treated. Innovations such as next-generation sequencing and liquid biopsies are transforming the diagnostic landscape by enabling early detection and personalized treatment regimens. Additionally, the development and approval of new drugs and treatment modalities, including targeted therapy and immunotherapy, are enhancing treatment efficacy and patient outcomes, thus propelling market growth.
Government initiatives and funding for cancer research and treatment also play a crucial role in the growth of the ovarian cancer diagnostics and therapeutics market. Increased government spending on healthcare infrastructure, coupled with supportive policies to facilitate cancer research, is encouraging the development of new diagnostic and therapeutic solutions. Public awareness campaigns and educational programs about the importance of early detection and treatment of ovarian cancer are also contributing to the growth of the market by increasing patient awareness and encouraging proactive healthcare measures.
Regionally, North America holds a dominant position in the ovarian cancer diagnostics and therapeutics market, owing to the presence of advanced healthcare infrastructure, high healthcare expenditure, and a strong focus on research and development. However, the Asia Pacific region is expected to witness the highest growth rate during the forecast period, driven by increasing healthcare investments, improving healthcare infrastructure, and a rising patient pool due to the increasing prevalence of ovarian cancer. The rapid economic growth in countries like China and India, coupled with growing awareness and availability of advanced healthcare solutions, are bolstering the market prospects in this region.
The ovarian cancer diagnostics and therapeutics market is segmented into two primary product types: diagnostics and therapeutics. The diagnostics segment includes various methods used for early detection and confirmation of ovarian cancer, such as imaging tests, blood tests, and biopsies. Imaging tests, including ultrasound and CT scans, are essential tools in diagnosing ovarian cancer as they provide detailed images of the ovaries and surrounding areas, helping detect any abnormal growths. Blood tests, particularly those measuring cancer antigens like CA-125, are widely utilized as they offer non-invasive and cost-effective means of preliminary cancer detection. Additionally, biopsy procedures, though invasive, provide definitive diagnosis by allowing pathological examination of ovarian tissue.
The therapeutics segment encompasses several treatment modalities used to manage and treat ovarian cancer, including chemotherapy, targeted therapy, immunotherapy, and hormonal therapy. Chemotherapy remains the cornerstone of ovarian cancer treatment, often administered post-surgery to eradicate any residual cancer cells. Despite its effectiveness, chemotherapy is associated with significant side effects, prompting
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Despite the progress made during the last two decades in the surgery and chemotherapy of ovarian cancer, more than 70% of advanced patients are with recurrent cancer and decease. Bevacizumab has been recently approved by FDA as a monotherapy for advanced ovarian cancer in combination with chemotherapy. Considering the cost, potential toxicity, and finding that only a portion of patients will benefit from these drugs, the identification of a new predictive method for the treatment of ovarian cancer remains an urgent unmet medical need. Prediction of therapeutic effects and individualization of therapeutic strategies are critical, but to the authors' best knowledge, there are no effective biomarkers that can be used to predict patient response to bevacizumab treatment for ovarian cancer. This dataset helps researchers to explore and develop methods to predict the therapeutic effect of patients with epithelial ovarian cancer to bevacizumab.
The dataset consists of de-identified 288 hematoxylin and eosin (H&E) stained whole slides with clinical information from 78 patients. The slides were collected from the tissue bank of the Tri-Service General Hospital and the National Defense Medical Center, Taipei, Taiwan. Whole Slide Images (WSIs) were acquired with a digital slide scanner (Leica AT2) with a 20x objective lens. The dimension of the ovarian cancer slides is 54342x41048 in pixels and 27.34 x 20.66mm on average. The bevacizumab treatment is effective in 162 and invalid in 126 of the dataset. Ethical approvals have been obtained from the research ethics committee of the Tri-Service General Hospital (TSGHIRB No.1-107-05-171 and No.B202005070), and the data were de-identified and used for a retrospective study without impacting patient care.
The clinicopathologic characteristics of patients were recorded by the data managers of the Gynecologic Oncology Center. Age, pre- and post-treatment serum CA-125 concentrations, histologic subtype, and recurrence, and survival status were recorded. A tumor, which is resistant to bevacizumab therapy, is defined as a measurable regrowth of the tumor or as a serum CA-125 concentration more than twice the value of the upper limit of normal during the treatment course for the bevacizumab therapy (i.e., the patient had the detectable disease or elevated CA-125 level following cytoreductive surgery combine with carboplatin/paclitaxel plus bevacizumab). A tumor, which is sensitive to bevacizumab therapy, is defined as no measurable regrowth of the tumor or as a serum CA-125 concentration under than twice the value of the upper limit of normal during the treatment course for the bevacizumab therapy.
This dataset is further described in the following publications:
This statistic shows the incidence rate for ovarian cancer among U.S. women from 2010 to 2014, by ethnicity. According to the data, non-Hispanic, white women have an incidence rate of ovarian cancer of 12 women per every 100,000 female population.
Breast, colorectal, ovarian, and endometrial cancers constitute approximately 30% of newly diagnosed cancer cases in Switzerland and affect more than 12,000 individuals annually. Several hundred of these patients are likely to carry known genetic mutations associated with HBOC or LS. Genetic testing for hereditary susceptibility to cancer can prevent many cancer deaths through early identification and engagement in high-risk management care that involves intensive surveillance, chemoprevention and/or prophylactic surgery. However, current rates of genetic testing indicate that many Swiss mutation carriers and their family members do not use cancer genetic services (counseling and/or testing), either due to lack of coordination of care or due to lack of communication about the mutation among family members. Cascade screening identifies and tests family members of a known mutation carrier. It determines whether asymptomatic family members are carriers of the identified mutation and proposes management options to reduce harmful outcomes. Robust evidence of basic science and descriptive population-based studies in Switzerland support the necessity of cascade screening for HBOC and LS. However, translation of this knowledge into public health interventions is lacking. Specific Aims of the CASCADE study are: 1. Survey Index Patients diagnosed with HBOC or LS from clinic-based genetic testing records and determine their cancer status and surveillance practices; needs for coordination of medical care; psychosocial needs; patient-provider and patient-family communication needs; quality of life; willingness to serve as advocates for cancer genetic services for blood relatives. 2. Survey first- and second-degree relatives, and first cousins identified from pedigrees and/or family history records of HBOC and LS Index Patients and determine their cancer and mutation status; cancer surveillance practices; needs for coordination of medical care; barriers and facilitators to using cancer genetic services; psychosocial needs; patient-provider and patient-family communication needs; quality of life; willingness to participate in a study designed to increase use of cancer genetic services. 3. Explore the influence of patient-provider communication about genetic cancer risk on patient-family communication and the acceptability of a family-based communication, coping, and decision support intervention with focus group(s) of mutation carriers and blood relatives.
Participants in this cohort are women identified from medical records and family records from the Department of Oncology , Lund. The inclusion criteria is that the woman should belong to families with a high risk of developing breast cancer as well as being known carriers of mutations in BRCA1 or BRCA2, or be related in the first or second generation to an individual with breast cancer or individual without breast cancer who are carriers of mutations in the genes BRCA1 or BRCA2. Study participants must be under 40 years old and still be menstruating.
“A family at high-risk for breast cancer” is considered if three women had been diagnosed with breast cancer and at least one of these was below age 50 years at diagnosis, or if two women had been diagnosed with breast cancer and at least one was below age 40 years at diagnosis, or if one woman diagnosed with breast cancer prior to age 30 years.
The collection, which is still ongoing, started in 1996 and consisted of 300 cases in 2010.
The selected women were contacted with a letter with information about the study and thereafter called and asked if they wanted to participate. A letter containing a comprehensive questionnaire was sent out to the women who had chosen to participate. The questions concerned areas such as fertility , breastfeeding, contraceptives, other medications, smoking and dietary issues. Participants were also called in for sampling and body measuremens (such as weight, length and different breast dimensions). Blood samples were taken on two occasions during the menstrual cycle : day 5-10 and ~ 18-23 days.
Purpose:
To study risk factors in young women of high risk for breast and ovarian cancer.
Data collection is ongoing. In 2010, the study consisted of 300 cases.
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The global ovarian cancer diagnostic market size was valued at USD 1.98 billion in 2025 and is projected to grow at a CAGR of 5.48% from 2025 to 2033. The increasing prevalence of ovarian cancer, the rising adoption of advanced diagnostic technologies, and the growing awareness about early detection are driving the market growth. Key market drivers include the increasing number of cancer cases, technological advancements, and the growing preference for personalized treatments. The market is segmented based on test type, biomarker, imaging modality, and genetic mutation. Major players in the market are Hologic, Beckman Coulter, Illumina, QIAGEN, and Qiagen. The North American region held the largest market share in 2025, followed by Europe and Asia-Pacific. Ovarian cancer is a leading cause of cancer deaths among women worldwide. The global ovarian cancer diagnostics market is projected to reach USD 3.2 billion by 2032, exhibiting a CAGR of 5.48% during the forecast period. Recent developments include: The global ovarian cancer diagnostics market size was valued at USD 1.98 billion in 2023 and is projected to reach USD 3.2 billion by 2032, exhibiting a CAGR of 5.48% during the forecast period. Rising prevalence of ovarian cancer, increasing adoption of advanced diagnostics techniques, and growing awareness about early detection are key factors driving market growth., Recent developments include the FDA approval of PNT2008, a novel biomarker for early detection, and the launch of non-invasive liquid biopsy tests for personalized treatment planning. Key players are focusing on strategic collaborations, acquisitions, and product innovation to gain a competitive edge.. Key drivers for this market are: Targeted therapies personalized medicine companion diagnostics biomarker discovery and liquid biopsy. Potential restraints include: Aging population biomarker advancements technological advancements favorable reimbursement policies rising government initiatives.
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According to the World Cancer Research Fund International, ovarian cancer is the eighth most frequent malignancy in women worldwide. In 2022, there were around 324,603 new cases of ovarian cancer across the globe. The lifetime risk of ovarian cancer for a woman is approximately 1 in 87. A woman has roughly a 1 in 130 lifetime probability of passing away from ovarian cancer. With a mere 29% 5-year survival rate, most cases (85%) are identified with either distant or regional stage illness. Several companies are engaged in research initiatives which is boosting the advanced ovarian cancer drug landscape significantly.
This statistic shows the number of registrations of newly diagnosed cases of ovarian cancer in England in 2022, by age group. The most affected age group was among 75 to 79 year olds, with 908 cases reported in 2022.