The oxytocin market is segmented by Indication (Antepartum, Postpartum), Distribution Channel (Hospital Pharmacies, Drug Stores, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

dataset for Van Cappellen, P., Way, B., Isgett, S. F., & Fredrickson, B. L. (in press). Effects of oxytocin administration on spirituality and emotional responses to meditation. Social Cognitive and Affective Neuroscience.

The table contains 27 products whose active ingredient are classified under the same pharmacologic class Oxytocin [CS].

The Oxytocin Market size was valued at USD 4.07 billion in 2023 and is projected to reach USD 8.89 billion by 2032, exhibiting a CAGR of 11.8 % during the forecasts period. Oxytocin is a hormone and neurotransmitter known for its role in social bonding, childbirth, and lactation. Produced in the brain's hypothalamus and released by the pituitary gland, it facilitates labor contractions during childbirth and stimulates milk ejection during breastfeeding. This hormone also influences social behaviors, promoting trust, empathy, and bonding between individuals. In medicine, synthetic oxytocin (Pitocin) is used to induce labor, manage postpartum hemorrhage, and assist in lactation. Advantages of oxytocin include its pivotal role in promoting maternal-infant bonding, aiding in reproductive health, and potentially improving social interactions and psychological well-being. Research suggests it may have therapeutic applications in disorders involving social deficits, although further studies are needed to fully understand its effects and benefits.

Both oxytocin (OT) and touch are key mediators of social attachment. In rodents, tactile stimulation elicits endogenous release of OT, potentially facilitating attachment and other forms of prosocial behavior, yet the relationship between endogenous OT and neural modulation remains unexplored in humans. Using serial sampling of plasma hormone levels during functional neuroimaging across two successive social interactions, we show that contextual circumstances of social touch influence not only current hormonal and brain responses but also later responses. Namely, touch from a male to his female romantic partner enhanced her subsequent OT release for touch from an unfamiliar stranger, yet females’ OT responses to partner touch were dampened following stranger touch. Hypothalamus and dorsal raphe activation reflected plasma OT changes during the initial social interaction. In the subsequent interaction, precuneus and parietal-temporal cortex pathways tracked time- and context-dependent va...

Antepartum Oxytocin: Used to induce or augment labor contractions when necessary to facilitate childbirth.Postpartum Oxytocin: Administered after delivery to promote uterine involution and reduce the risk of post-partum hemorrhage. Recent developments include: August 2022:The US patent for the painkiller intranasal oxytocin (TNX-1900) was awarded to Tonix Pharmaceuticals. Under the heading "Magnesium-Containing Oxytocin Formulations and Methods of Use," the patent sought to protect patients from pain—including migraine headaches—by employing intranasal formulations of oxytocin that contain magnesium. Tonix should have U.S. market exclusivity through January 2036 thanks to this invention, barring any potential patent term extensions., May 2020:Carbetocin Ferring, a heat-stable formulation approved by Swissmedic, is used to prevent postpartum hemorrhage in all births. This drug is the first to be approved under the new MAGHP (Marketing Authorization for Global Health Products) and Swissmedic procedures.. Notable trends are: Increasing number of difficulties during childbirth is driving the market growth.

The market size of the oxytocin market size and forecast is categorized based on Type (Injection, Nasal Spray) and Application (For Baby Born, For Comestic, Others) and geographical regions (North America, Europe, Asia-Pacific, South America, and Middle-East and Africa).

The provided report presents market size and predictions for the value of oxytocin market size and forecast, measured in USD million, across the mentioned segments.

Social behavior plays an essential role in daily life. The neuropeptide oxytocin has generated considerable interest for its role in social behavior and potential to treat psychiatric disorders characterised by social dysfunction. This study advances our understanding of the neurobiological substrates of social behavior by interrogating human whole-brain maps of oxytocin pathway gene expression, demonstrating these genes are enriched in central, temporal, and olfactory brain regions. We also show via large-scale fMRI meta-analysis that these gene expression patterns correspond with brain regions involved in emotion and motivation processing. These results provide a proof-of-principle demonstration of corresponding mental states with gene expression patterns of a neuropeptide pathway involved in complex human behaviors, and identify neural network targets for future oxytocin trials.

A collection of 56 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection includes unthresholded maps for all the analyses conducted in the study. Only the conjunction maps are presented thresholded at voxel level p=0.002.

The market size of the oxytocin market size and forecast 2 is categorized based on Application (Odinopoeia, Labor-inducing Drug, Other) and Product (10IU, 5IU, 200IU, Other) and geographical regions (North America, Europe, Asia-Pacific, South America, and Middle-East and Africa).

The provided report presents market size and predictions for the value of oxytocin market size and forecast 2, measured in USD million, across the mentioned segments.

A collection of 22 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

All 22 component maps included in: "Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women." http://biorxiv.org/content/early/2016/08/09/068585

A collection of 35 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection contains fMRI data from a study in which healthy males received L-DOPA (100 mg + 25 mg carbidopa), intranasal oxytocin (24 IU), or placebo using a double-blind placebo-controlled cross-over design. In each session, participants performed a probabilistic reinforcement learning task with potential rewards for themselves, an anonymous other participant, or no one, during functional magnetic resonance imaging. Computational models of reinforcement learning were used to calculate prediction errors (PEs) and learning rates. Contrasts involve the factors drug (L-DOPA, oxytocin, placebo) and recipient (self, other, no one).

(Note that paper links to https://identifiers.org/neurovault.collection:13141, but this collection was accidentally deleted.)

Get the sample copy of Oxytocin Market Report 2024 (Global Edition) which includes data such as Market Size, Share, Growth, CAGR, Forecast, Revenue, list of Oxytocin Companies (Merck & Co, Pfizer, Mylan, GSK, Novartis, Roche, Grindeks), Market Segmented by Type (Oxytocin Injection, Dry Powder Oxytocin), by Application (For Baby Born, For Comestic, Others)

Get the sample copy of Oxytocin Receptor Antagonists Market Report 2024 (Global Edition) which includes data such as Market Size, Share, Growth, CAGR, Forecast, Revenue, list of Oxytocin Receptor Antagonists Companies (Ferring, Sun Pharmaceutical, Biopas, PolyPeptide, CS Bio), Market Segmented by Type (Non Peptide and Orally Active Oxytocin Receptor Antagonist, High Affinity Human Oxytocin (OT) Receptor Antagonist), by Application (Animals, People)

Unthresholded map

Collection description

This collection includes unthresholded maps for all the analyses conducted in the study. Only the conjunction maps are presented thresholded at voxel level p=0.002.

Subject species

homo sapiens

Modality

fMRI-BOLD

Analysis level

group

Cognitive paradigm (task)

pleasantness rating task

Map type

F

unit: µU/ml per creatinin g/L.

The dataset contains the files (DARE_Workfile, Empathy_Workfile) used for the analyses of the study published by Fragkaki and Cima (2019) in Psychoneuroendocrinology. The study examined the effect of oxytocin administration on empathy and emotion recognition in 100 male adolescents living in residential youth care facilities. The study had a randomized, double-blind, placebo-controlled, within-subject design. The study included 3 sessions: screening session and two experimental sessions. In the experimental sessions, the participants received oxytocin in one session and placebo in the other session and performed the same experimental tasks on empathy and emotion recognition 30 min after administration. The order of the sprays as well as the order of the tasks were randomized using computer randomization. We performed mixed modeling to examined the effect of oxytocin on the outcome variables. The file “Documentation-ReadMe” describes the trial information, methodology, and the variables included in the datasets. The file "icu_dutch" is the Dutch version of the Inventory of callous-unemotional traits, the file ctq_dutch" is the Dutch version of the Childhood trauma questionnaire", and the file "ades_dutch" is the Dutch version of the Adolescent dissociative experiences scale.

The global oxytocin market size is forecast to reach USD 193.02 million and estimated to expand at a CAGR of 9.3% by 2032, according to PMR.