Pitocin is a prescription injectable medication containing oxytocin, used to induce or strengthen labor by stimulating uterine contractions. It is administered intravenously and manufactured by Endo USA, Inc. This information was generated using AI and is provided for informational and research purposes only.

A collection of 3 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

The Oxytocin Market Report is Segmented by Indication (Antepartum, Postpartum), Route of Administration (Parenteral, Intranasal, Oromucosal), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, South America). The Market Forecasts are Provided in Terms of Value (USD).

The dataset contains the files (DARE_Workfile, Empathy_Workfile) used for the analyses of the study published by Fragkaki and Cima (2019) in Psychoneuroendocrinology. The study examined the effect of oxytocin administration on empathy and emotion recognition in 100 male adolescents living in residential youth care facilities. The study had a randomized, double-blind, placebo-controlled, within-subject design. The study included 3 sessions: screening session and two experimental sessions. In the experimental sessions, the participants received oxytocin in one session and placebo in the other session and performed the same experimental tasks on empathy and emotion recognition 30 min after administration. The order of the sprays as well as the order of the tasks were randomized using computer randomization. We performed mixed modeling to examined the effect of oxytocin on the outcome variables. The file “Documentation-ReadMe” describes the trial information, methodology, and the variables included in the datasets. The file "icu_dutch" is the Dutch version of the Inventory of callous-unemotional traits, the file ctq_dutch" is the Dutch version of the Childhood trauma questionnaire", and the file "ades_dutch" is the Dutch version of the Adolescent dissociative experiences scale.

A collection of 22 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

All 22 component maps included in: "Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women." http://biorxiv.org/content/early/2016/08/09/068585

Chemical Interactions for Oxytocin curated by BioGRID (https://thebiogrid.org); DEFINITION: Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

Oxytocin is a neuropeptide released in the central nervous system, which is involved in a wide range of behaviors including reproduction, parental care, and pair bonding. In addition, peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labor. Oxytocin is produced mainly in the paraventricular nucleus (PVN) and supraoptic nucleus of the hypothalamus. This study describes a neural circuit routing auditory information about infant vocalizations to mouse oxytocin neurons. They performed in vivo electrophysiological recordings and photometry from identified oxytocin neurons in awake maternal mice presented with pup calls. For this study, they made cell-attached and whole-cell recordings from PVN oxytocin neurons and other optically-unresponsive PVN neurons in awake head-fixed mouse dams. The dataset contains electrophysiology, behavioral, histology, and fiber photometry data. This study reveals a circuit that unlocks central oxytocin release and maternal behavior in response to pup calls.

The table includes 3 products with the active ingredient Oxytocin Acetate.

The size of the Oxytocin Supplement market was valued at USD 90 million in 2023 and is projected to reach USD 153.25 million by 2032, with an expected CAGR of 7.9% during the forecast period.

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups . The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence . The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) . GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice . Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs .

Global trade data of Oxytocin under 30049099000, 30049099000 global trade data, trade data of Oxytocin from 80+ Countries.

This study examined oxytocin expression in experimental models of Alzheimer’s disease (AD), and evaluated the therapeutic potential of treatment with oxytocin. They investigated changes in oxytocin expression in APP/PS1 mouse model and developed a chronic intranasal treatment protocol to increase oxytocin levels in the brain. Then, tested oxytocin as a potential approach to attenuate microglial activation and reverse memory deficits. This dataset includes source data used to assemble different figures in the publication. The source data contains data about hypothalamic expression of oxytocin is reduced in AD models, chronic intranasal administration of oxytocin increases hippocampal oxytocin and attenuates fear response in mice, cellular and molecular impact of intranasal oxytocin in APP/PS1 mouse brains, oxytocin attenuates AβO-induced microglial activation in vitro, and intranasal oxytocin reverses social and non-social memory deficits in aged APP/PS1 mice.

Notes: PPH: postpartum hemorrhage; CEmONC facilities: facilities with comprehensive emergency obstetric and newborn care; BEmONC facilities: facilities with basic emergency obstetric and newborn care; QALY: quality-adjusted life years†Incremental cost of Uniject relative to the traditional use of oxytocin in ampulesΩExpressed as the proportion of the gap (between the ideal of 100% of women receiving oxytocin and the proportion currently receiving it) which could potentially be reduced by using Uniject instead of oxytocin in ampules.For the probabilistic sensitivity analysis (PSA) the “probability of PPH without oxytocin”, the “conditional probability of severe PPH (given PPH)”, the “Risk of hysterectomy due to severe PPH”, the “Relative risk of PPH when receiving oxytocin” and the “Oxytocin effectiveness (% gap reduction)” were assumed to follow a Beta distribution. Alpha and beta parameters were approximated considering the mean the main estimate and as standard deviation the 10% of the mean value. The “incremental cost of Uniject” was assumed to follow a Gamma distribution. Alpha and beta parameters were approximated in these cases considering the mean as the main estimate and as standard deviation the 25% of the mean value.Global parameters: Base case values, ranges used in the sensitivity analysis and data sources.

Demographic data, illness characteristics, basal and induced oxytocin levels and dimensions of empathy in patients with schizophrenia and healthy controls.

The table contains 26 products whose active ingredient are classified under the same pharmacologic class Oxytocin [CS].

The Oxytocin Injection market was valued at $4.8 billion in 2025 and is projected to reach $7.2 billion by 2033, growing at 5.3% CAGR.

Abstract Domestication is of unquestionable importance to the technological revolution that has given rise to modern human societies. In this study, we analyzed the DNA and protein sequences of six genes of the oxytocin and arginine vasopressin systems (OXT-OXTR; AVP-AVPR1a, AVPR1b and AVPR2) in 40 placental mammals. These systems play an important role in the control of physiology and behavior. According to our analyses, neutrality does not explain the pattern of molecular evolution found in some of these genes. We observed specific sites under positive selection in AVPR1b (ω = 1.429, p = 0.001) and AVPR2 (ω= 1.49, p = 0.001), suggesting that they could be involved in behavior and physiological changes, including those related to the domestication process. Furthermore, AVPR1a, which plays a role in social behavior, is under relaxed selective constraint in domesticated species. These results provide new insights into the nature of the domestication process and its impact on the OXT-AVP system.

The global oxytocin testing kits market is anticipated to reach USD 1,351.4 million by 2035, rising from USD 740.5 million in 2025 at a 6.2% CAGR.

Top Countries Manufacturing, Distributing, and Scaling Oxytocin Testing Kits

Global Oxytocin Market valued at USD 100 million, projected to reach USD 2.457 billion by 2035, driven by labor induction, postpartum hemorrhage prevention, and veterinary applications.