Pitocin is a prescription injectable medication containing oxytocin, used to induce or strengthen labor by stimulating uterine contractions. It is administered intravenously and manufactured by Endo USA, Inc. This information was generated using AI and is provided for informational and research purposes only.

A collection of 3 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

The Oxytocin Market Report is Segmented by Indication (Antepartum, Postpartum), Route of Administration (Parenteral, Intranasal, Oromucosal), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, South America). The Market Forecasts are Provided in Terms of Value (USD).

A collection of 56 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection includes unthresholded maps for all the analyses conducted in the study. Only the conjunction maps are presented thresholded at voxel level p=0.002.

The dataset contains the files (DARE_Workfile, Empathy_Workfile) used for the analyses of the study published by Fragkaki and Cima (2019) in Psychoneuroendocrinology. The study examined the effect of oxytocin administration on empathy and emotion recognition in 100 male adolescents living in residential youth care facilities. The study had a randomized, double-blind, placebo-controlled, within-subject design. The study included 3 sessions: screening session and two experimental sessions. In the experimental sessions, the participants received oxytocin in one session and placebo in the other session and performed the same experimental tasks on empathy and emotion recognition 30 min after administration. The order of the sprays as well as the order of the tasks were randomized using computer randomization. We performed mixed modeling to examined the effect of oxytocin on the outcome variables. The file “Documentation-ReadMe” describes the trial information, methodology, and the variables included in the datasets. The file "icu_dutch" is the Dutch version of the Inventory of callous-unemotional traits, the file ctq_dutch" is the Dutch version of the Childhood trauma questionnaire", and the file "ades_dutch" is the Dutch version of the Adolescent dissociative experiences scale.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

Abstract Domestication is of unquestionable importance to the technological revolution that has given rise to modern human societies. In this study, we analyzed the DNA and protein sequences of six genes of the oxytocin and arginine vasopressin systems (OXT-OXTR; AVP-AVPR1a, AVPR1b and AVPR2) in 40 placental mammals. These systems play an important role in the control of physiology and behavior. According to our analyses, neutrality does not explain the pattern of molecular evolution found in some of these genes. We observed specific sites under positive selection in AVPR1b (ω = 1.429, p = 0.001) and AVPR2 (ω= 1.49, p = 0.001), suggesting that they could be involved in behavior and physiological changes, including those related to the domestication process. Furthermore, AVPR1a, which plays a role in social behavior, is under relaxed selective constraint in domesticated species. These results provide new insights into the nature of the domestication process and its impact on the OXT-AVP system.

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups . The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence . The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) . GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice . Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs .

A collection of 35 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection contains fMRI data from a study in which healthy males received L-DOPA (100 mg + 25 mg carbidopa), intranasal oxytocin (24 IU), or placebo using a double-blind placebo-controlled cross-over design. In each session, participants performed a probabilistic reinforcement learning task with potential rewards for themselves, an anonymous other participant, or no one, during functional magnetic resonance imaging. Computational models of reinforcement learning were used to calculate prediction errors (PEs) and learning rates. Contrasts involve the factors drug (L-DOPA, oxytocin, placebo) and recipient (self, other, no one).

(Note that paper links to https://identifiers.org/neurovault.collection:13141, but this collection was accidentally deleted.)

Global trade data of Oxytocin under 30049099000, 30049099000 global trade data, trade data of Oxytocin from 80+ Countries.

The size of the Oxytocin Supplement market was valued at USD 90 million in 2023 and is projected to reach USD 153.25 million by 2032, with an expected CAGR of 7.9% during the forecast period.

A collection of 1 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

The aim of this study was to investigate the effect of intranasal OXT on amygdala resting-state functional connectivity (rsFC) in BDD. In a randomized, double-blind, cross-over design, participants received intranasal OXT (24 IU) or placebo before resting-state functional magnetic resonance imaging in 19 BDD participants and 17 demographically matched healthy controls. The left and right amygdala were seeded as regions of interest, and temporal correlations between the amygdalae and all other voxels comprising cortical and subcortical grey matter were investigated.

Demographic data, illness characteristics, basal and induced oxytocin levels and dimensions of empathy in patients with schizophrenia and healthy controls.

The table contains 26 products whose active ingredient are classified under the same pharmacologic class Oxytocin [CS].

The Oxytocin Market will grow from USD 1.55 Billion in 2025 to USD 2.31 Billion by 2031 at a 6.91% CAGR.

The global oxytocin testing kits market is anticipated to reach USD 1,351.4 million by 2035, rising from USD 740.5 million in 2025 at a 6.2% CAGR.

Top Countries Manufacturing, Distributing, and Scaling Oxytocin Testing Kits

Global Oxytocin Market valued at USD 100 million, projected to reach USD 2.457 billion by 2035, driven by labor induction, postpartum hemorrhage prevention, and veterinary applications.

Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing cells in the anterior subdivision of the ventromedial hypothalamus as a key circuit motif for defeat-induced social avoidance through a series of functional manipulation and recording experiments in mice. The dataset contains fiber photometry recording data, behavior annotations, tracking, and raw representative histology images. These data reveal the crucial role of oxytocin in social behavior plasticity and expanded the list of regions through which oxytocin can modulate negative social responses.

Oxytocin Injection Market size, share, and trend analysis indicates growth from USD 873 Million in 2025 to USD 1.64 Billion by 2035, at a CAGR of 6.5%

SPM{T_[237.0]} - contrast 3: PE_plac_noone

Collection description

This collection contains fMRI data from a study in which healthy males received L-DOPA (100 mg + 25 mg carbidopa), intranasal oxytocin (24 IU), or placebo using a double-blind placebo-controlled cross-over design. In each session, participants performed a probabilistic reinforcement learning task with potential rewards for themselves, an anonymous other participant, or no one, during functional magnetic resonance imaging. Computational models of reinforcement learning were used to calculate prediction errors (PEs) and learning rates. Contrasts involve the factors drug (L-DOPA, oxytocin, placebo) and recipient (self, other, no one).

(Note that paper links to https://identifiers.org/neurovault.collection:13141, but this collection was accidentally deleted.)

Subject species

homo sapiens

Modality

fMRI-BOLD

Analysis level

group

Cognitive paradigm (task)

Probabilistic Selection Task

Map type

T