[265 Pages Report] Global Oxytocin market are set to experience a significant growth of 9.0% CAGR from 2022 to 2030, with an estimated market value of around US$ 83.0 Mn as of 2022. As per Future Market Insights’ projections, Postpartum type holds a substantial share of over 88.8% in 2021 within the Global market.

Data Points	Market Insights
Market Value 2021	US$ 76.0 Million
Market Value 2022	US$ 83.0 Million
Market Value 2030	US$ 164.9 Million
CAGR 2022-2030	9.0%
Market Share of Top 5 Countries	51.2%
Key Market Players	Pfizer Inc., Novartis AG, Ferring B.V., Fresenius Kabi LLC, Hikma Pharmaceuticals PLC, Endo International plc. (Par Sterile Products, LLC), Teva Pharmaceutical Industries Ltd., Mylan N.V., Wockhardt Ltd., Sun Pharmaceutical Industries Ltd., and Yuhan Corporation

How The Market Progressed Till June 2022?

Particulars	Details
H1, 2021	8.41%
H1, 2022 Projected	8.96%
H1, 2022 Outlook	8.96%
BPS Change - H1, 2022 (O) - H1, 2022 (P)	(-) 10 ↓
BPS Change - H1, 2022 (O) - H1, 2021	(+) 45 ↑

Report Scope as per Oxytocin Industry Analysis

Attribute	Details
Forecast Period	2022 to 2030
Historical Data Available for	2015 to 2021
Market Analysis	US$ Million for Value
Key Regions Covered	North America, Latin America, Europe, South Asia, East Asia, Oceania and Middle East & Africa
Key Countries Covered	USA, Canada, Brazil, Mexico, Argentina, Germany, UK, France, Italy, Spain, Russia, China, Japan, South Korea, India, Malaysia, Indonesia, Thailand, Australia,New Zealand, GCC Countries, Turkey, Egypt, Nigeria, Algeria, Morocco, Kenya
Key Market Segments Covered	Product Distribution Channel and Region
Key Companies Profiled	Pfizer Inc. Novartis AG Ferring B.V. Fresenius Kabi LLC Hikma Pharmaceuticals PLC Endo International plc. (Par Sterile Products, LLC) Teva Pharmaceutical Industries Ltd. Mylan N.V. Wockhardt Ltd. Sun Pharmaceutical Industries Ltd. Yuhan Corporation
Pricing	Available upon Request

Report Metric	Details
Forecast Period	2023 to 2030
Base Year	2022
Historic Years	2021 (Customizable to 2015 - 2020)
Quantitative Units	Revenue in USD Billion, Volumes in Units, Pricing in USD
Segments Covered	Type (Branded, Generic), Application (Incomplete Abortion, Pregnancy loss, Bleeding Control, Parturition, Contraction Stress Test, Psychiatric Disorders, Lactation Control), Organism Type (Human, Animal), Sex (Men, Women), Route of Administration (Intranasal, Intravenously, Intramuscular), End-Users (Clinics, Hospitals, Birth Center, Mental Health Facility), Distribution Channel (Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy, Others)
Countries Covered	U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America
Market Players Covered	Bimeda, Inc. (Ireland), Grindeks (Latvia), KAPL (U.S.), Novartis AG (Switzerland), Pfizer Inc. (U.S.), AnkeBio Co., Ltd (China), Aspen Veterinary Resources, LTD (U.S.), Hemmo Pharmaceuticals Pvt Ltd (India), Shenzhen JYMed Technology Co., Ltd (China), Systacare Remedies (U.S.), AdvaCare Pharma (India), Sundent Pharm Group (Netherlands), Fresenius Kabi USA (U.S.), SAINTROY LIFESCIENCE (India), Sri Pharmacare (India)
Market Opportunities	The rising use of oxytocin in the area of pregnancy will act as an opportunity

The oxytocin market is segmented by Indication (Antepartum, Postpartum), Distribution Channel (Hospital Pharmacies, Drug Stores, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups . The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence . The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) . GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice . Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs .

Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing cells in the anterior subdivision of the ventromedial hypothalamus through a series of functional manipulation and recording experiments. The dataset contains fiber photometry recording data, behavior annotations, and tracking and raw representative histology images. These data reveal the crucial role of oxytocin in social behavior plasticity and expanded the list of regions through which oxytocin can modulate negative social responses.

Oxytocin Injection Market Report 2024, Market Size, Share, Growth, CAGR, Forecast, Revenue, list of Oxytocin Injection Companies (JHP Pharmaceuticals, Agrilab, Novartis, Grindex, Bayer, Pfizer, Hybio Pharmaceutical, Bimeda, GSK, Kepro B.V., Shanghai Hefeng, Renjian Pharmaceutical), Market Segmented by Application (Animal Use, Human Use), by Type (Oxytocin, Carbetocin)

A collection of 35 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection contains fMRI data from a study in which healthy males received L-DOPA (100 mg + 25 mg carbidopa), intranasal oxytocin (24 IU), or placebo using a double-blind placebo-controlled cross-over design. In each session, participants performed a probabilistic reinforcement learning task with potential rewards for themselves, an anonymous other participant, or no one, during functional magnetic resonance imaging. Computational models of reinforcement learning were used to calculate prediction errors (PEs) and learning rates. Contrasts involve the factors drug (L-DOPA, oxytocin, placebo) and recipient (self, other, no one).

(Note that paper links to https://identifiers.org/neurovault.collection:13141, but this collection was accidentally deleted.)

Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies. Although studies have shown increased cerebrospinal fluid (CSF) OT levels following IN administration, this does not unequivocably demonstrate that the peripherally administered OT is entering the CSF. For example, it has been suggested that peripheral delivery of OT could lead to central release of endogenous OT. It is also unknown whether the IN route provides for more efficient entry of the peptide into the CSF compared to the intravenous (IV) route, which requires blood-brain barrier penetration. To address these questions, we developed a sensitive and specific quantitative mass spectrometry assay that distinguishes labeled (d5-deuterated) from endogenous (d0) OT. We administered d5 OT (80 IU) to six nonhuman primates via IN and IV routes as well as IN saline as a control condition. We measured plasma and CSF concentrations of administered and endogenous OT before (t=0) and after (t=10, 20, 30, 45 and 60?min) d5 OT dosing. We demonstrate CSF penetrance of d5, exogenous OT delivered by IN and IV administration. Peripheral administration of d5 OT did not lead to increased d0, endogenous OT in the CSF. This suggests that peripheral administration of OT does not lead to central release of endogenous OT. We also did not find that IN administration offered an advantage compared to IV administration with respect to achieving greater CSF concentrations of OT.

The table includes 68 products with the active ingredient Oxytocin.

Market Overview:

The global injection Oxytocin market is expected to grow at a CAGR of 5.5% from 2022 to 2030. The growth in the market can be attributed to the increasing demand for oxytocin for baby born and cosmetic applications, and rising awareness about the benefits of oxytocin therapy. The global injection oxytocin market is segmented by type, application, and region. By type, the market is divided into injection and freeze-dried injection. By application, it is classified into baby born, cosmetic surgery/aesthetics procedures (such as wrinkle removal), labor induction/augmentation (such as speeding up labor), postpartum hemorrhage prevention & treatment (PPH), other applications (including Autism Spectrum Disorder [ASD], cerebral palsy [CP], chronic obstructive pulmonary disease [COPD]). Geographically, it is analyzed across North America, Latin America, Europe, Asia Pacific, and Middle East & Africa.

Product Definition:

Injection oxytocin is a hormone that is naturally produced by the body. It plays an important role in labor and birth, as well as in breastfeeding. Oxytocin can also be given as a medication to induce labor or to help with breast milk production.

Injection:

Injection oxytocin is a hormone that is produced in the hypothalamus and released into the bloodstream. It is sometimes called "the love hormone" because it helps to create feelings of trust, affection, and security. Injection oxytocin is used to treat conditions such as labor pains, postpartum depression, and autism.

Freeze-dried Injection:

Freeze-dried Injection oxytocin is a form of oxytocin that is freeze-dried. It is used to treat baby born, for domestic, and for others. It provides long-term stability and is easy to administer. It is made from pure oxytocin and has the same effects as oxytocin that is injected.

Application Insights:

For baby born was the largest application segment in the global market and accounted for over 60% of total revenue in 2015. A rise in the number of female reproductive organ donors is expected to boost demand for this drug, which is used as a labor-inducing agent during childbirth. In addition, growing awareness among women regarding pain management during pregnancy will also drive demand over the forecast period. The freeze-dried injection is anticipated to be the fastest growing application segment with a CAGR of around 12% from 2022 to 2030 owing to advantages such as fewer needle pricks and faster absorption by vein compared with other forms of injections. Owing to the increase in adoption rates across various countries including India, China, Japan, Brazil, etc., this drug has become an important tool for treating domestic animals such as horses and dogs along with humans which further boosts its consumption globally.

Regional Analysis:

North America dominated the global market in terms of revenue share in 2019. The region is expected to continue its dominance over the forecast period owing to increasing R&D activities and rising awareness about new technologies for safe delivery. In addition, the presence of key players with extensive research & development capabilities is also likely to support regional growth. Asia Pacific market was valued at USD X million in 2019 and is anticipated to witness lucrative CAGR over the forecast period due to the growing population, improving healthcare infrastructure along with high unmet medical needs, especially regarding premature birth complications are some factors driving regional growth. In Latin America, Oxytocin Injection has been approved by regulatory agencies as a part of national public health programs aimed at reducing the infant mortality rate (IMR).

Growth Factors:

• Increasing demand from pregnant women for the prevention of post-partum hemorrhage.
• Rising prevalence of gynecological disorders such as uterine fibroids, endometriosis, and ovarian cysts.
• Growing awareness about the benefits of oxytocin injection in childbirth and labor induction.
• An increasing number of clinical studies support the use of oxytocin injection in various medical applications.
• Technological advancements have led to the development of new and improved formulations.

Report Scope

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Report Attributes	Report Details

dataset for Van Cappellen, P., Way, B., Isgett, S. F., & Fredrickson, B. L. (in press). Effects of oxytocin administration on spirituality and emotional responses to meditation. Social Cognitive and Affective Neuroscience.

Little is known about how intranasally administered oxytocin reaches the brain and modulates social behavior and cognition. Pupil dilation is a sensitive index of attentional allocation and effort, and inter-individual variability in pupil diameter during performance of social-cognitive tasks may provide a better assessment of pharmacological effects on the brain than behavioral measures. Here, we leverage the close relationship between pupil and neural activity to inform our understanding of nose-to-brain oxytocin routes and possible dose-response relationships. To this end, we assessed pupil diameter data from a previously reported functional magnetic resonance imaging (fMRI) study under four treatment conditions-including two different doses of intranasal oxytocin using a novel Breath Powered nasal device, intravenous (IV) oxytocin, and placebo-and investigated the association with amygdala activation in response to emotional stimuli. The study used a randomized, double-blind, double-dummy, crossover design, with 16 healthy male adults administering a single-dose of these four treatments. A significant main effect of treatment condition on pupil diameter was observed. Posthoc tests revealed reduced pupil diameter after 8IU intranasal oxytocin compared to placebo, but no significant difference between 8IU intranasal oxytocin and either 24IU intranasal oxytocin or IV oxytocin treatment conditions. Analysis also showed a significant relationship between pupil diameter and right amygdala activation after 8IU intranasal oxytocin. Although there was no significant difference between 8IU intranasal oxytocin and IV oxytocin on right amygdala activity and pupil diameter, the significant difference between 8IU intranasal oxytocin and placebo is consistent with the hypothesis that oxytocin can travel to the brain via a nose-to-brain route.

Oxytocin Market is growing at a good pace & it is estimated that the market will gain huge shares in the forecasted period

Injection Oxytocin Sales Market is expected to increase at a CAGR of 3 to 5 percent, from its estimated valuation of USD XX Million by 2031

27 Yemen import shipment records of Oxytocin with prices, volume & current Buyer’s suppliers relationships based on actual Yemen import trade database.

The global oxytocin market is expected to grow at a CAGR of 6.1% from 2024 to 2030.

Abstract Decision-making in groups is a remarkable and decisive element of human societies. Humans are able to organize themselves in groups, engage in collaborative decision-making processes and arrive at a binding agreement, even in the absence of unanimous consent. However, the transfer of decision-making autonomy requires a willingness to deliberately expose oneself to the decisions of others. A lack of trust in the abilities of others or of the underlying decisionmaking process, i.e. public trust, can lead to a breakdown of organizations in political or economic domains. Recent studies indicate that the biological basis of trust on an individual level is related to Oxytocin, an endogenous neuropeptide and hormone, which is also associated with pro-social behavior and positive conflict resolution. However, little is known about the effects of Oxytocin on the inclination of individuals to form or join groups and to deliberately engage in collaborative decision-making processes. Here, we show that intranasal administration of Oxytocin (n = 60) compared to placebo (n = 60) in males causes an adverse effect on the choice for forming groups in the presence of a competitive environment. In particular, Oxytocin negatively affects the willingness to work collaboratively in a p-Beauty contest game, whereas the effect is most pronounced for participants with relatively high strategic sophistication. Since our data provide initial evidence that Oxytocin has a positive effect on strategic thinking and performance in the p-Beauty contest game, we argue that the adverse effect on group formation might be rooted in an enhanced strategic sophistication of participants treated with Oxytocin.

Both oxytocin (OT) and touch are key mediators of social attachment. In rodents, tactile stimulation elicits endogenous release of OT, potentially facilitating attachment and other forms of prosocial behavior, yet the relationship between endogenous OT and neural modulation remains unexplored in humans. Using serial sampling of plasma hormone levels during functional neuroimaging across two successive social interactions, we show that contextual circumstances of social touch influence not only current hormonal and brain responses but also later responses. Namely, touch from a male to his female romantic partner enhanced her subsequent OT release for touch from an unfamiliar stranger, yet females’ OT responses to partner touch were dampened following stranger touch. Hypothalamus and dorsal raphe activation reflected plasma OT changes during the initial social interaction. In the subsequent interaction, precuneus and parietal-temporal cortex pathways tracked time- and context-dependent va...

6918 Global import shipment records of Oxytocin with prices, volume & current Buyer’s suppliers relationships based on actual Global import trade database.