Complete dataset included in the full report. Detailed tables, regional splits, forecasts, and methodologies are available with purchase.

Pitocin is a prescription injectable medication containing oxytocin, used to induce or strengthen labor by stimulating uterine contractions. It is administered intravenously and manufactured by Endo USA, Inc. This information was generated using AI and is provided for informational and research purposes only.

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A collection of 56 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection includes unthresholded maps for all the analyses conducted in the study. Only the conjunction maps are presented thresholded at voxel level p=0.002.

Aggregated anonymized self-reports from PeptIQ users tracking Oxytocin.

Experimental studies exploring the effects of intranasal oxytocin are typically underpowered due to small samples. Open access to experimental data and procedures and the use of previously employed measures is critical to building more robust and replicable findings, especially in less studied areas of oxytocin research. In this paper, data is provided from a double-blind placebo-controlled crossover study exploring the effects of intranasal oxytocin (IN-OT: 24 IU) on social preference to romantic partners, parents, peers, and strangers. Young adults (N=44; 91% female) in committed dating relationships completed three phases of data collection including a screening survey followed by two laboratory visits. In addition to romantic partner-, and stranger attraction ratings, the data is the first to provide comparisons between attachment and social preference ratings to parents, close friends, and romantic partners under placebo and IN-OT conditions. The data also include differences by situational and life history factors known to moderate oxytocin effects. The detailed protocol, and dataflow can be accessed to verify the analysis and findings or to conduct a replication study. The standardized experimental design and common IN-OT protocol add to the capacity for a meta-analysis exploring oxytocin effects on partner preference, and may also be directly ported to existing or future studies with related questions to increase sample size and power.

The oxytocin market was valued at $1.52 billion in 2025 and is projected to reach $2.54 billion by 2034, growing at 5.8% CAGR.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

The dataset contains the files (DARE_Workfile, Empathy_Workfile) used for the analyses of the study published by Fragkaki and Cima (2019) in Psychoneuroendocrinology. The study examined the effect of oxytocin administration on empathy and emotion recognition in 100 male adolescents living in residential youth care facilities. The study had a randomized, double-blind, placebo-controlled, within-subject design. The study included 3 sessions: screening session and two experimental sessions. In the experimental sessions, the participants received oxytocin in one session and placebo in the other session and performed the same experimental tasks on empathy and emotion recognition 30 min after administration. The order of the sprays as well as the order of the tasks were randomized using computer randomization. We performed mixed modeling to examined the effect of oxytocin on the outcome variables. The file “Documentation-ReadMe” describes the trial information, methodology, and the variables included in the datasets. The file "icu_dutch" is the Dutch version of the Inventory of callous-unemotional traits, the file ctq_dutch" is the Dutch version of the Childhood trauma questionnaire", and the file "ades_dutch" is the Dutch version of the Adolescent dissociative experiences scale.

A collection of 12 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

Chemical Interactions for Oxytocin curated by BioGRID (https://thebiogrid.org); DEFINITION: Synthetic 9 residue cyclic peptide. The hormone is prepared synthetically to avoid possible contamination with vasopressin (ADH) and other small polypeptides with biologic activity.

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A collection of 5 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

Randomized, double-blind, placebo-controlled, cross-over design to compare the impacts of a single intranasal oxytocin dose on amygdala connectivity among individuals with schizophrenia (n = 22) versus healthy controls (n = 24).

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This pathway shows a high-level overview of oxytocin signalling.

This dataset accompanies the research article "Oxytocin signaling regulates maternally-directed behavior during early life". It includes Matlab data structures for each of the figures in the article. Within each structure are entries for each panel in the figure, including all data points presented in the panel. Panels that do not include any quantitative data (for example images) are also associated with entries in the matlab structures, but these entries are empty.

Governed scientific-intelligence record for Oxytocin, including represented evidence, uncertainty, provenance, regulatory context, and separately labeled observational information.

It has been demonstrated that secretion of several hormones can be classically conditioned, however, the underlying brain responses of such conditioning have never been investigated before. In this study we aimed to investigate how oxytocin administration and classically conditioned oxytocin influence brain responses. In total, 88 females were allocated to one of three groups: oxytocin administration, conditioned oxytocin, or placebo, and underwent an experiment consisting of three acquisition and three evocation days. Participants in the conditioned group received 24 IU of oxytocin together with a conditioned stimulus (CS) during three acquisition days and placebo with the CS on three evocation days. The oxytocin administration group received 24 IU of oxytocin and the placebo group received placebo during all days. On the last evocation day, fMRI scanning was performed for all participants during three tasks previously shown to be affected by oxytocin: presentation of emotional faces, crying baby sounds and heat pain. Region of interest analysis revealed that there was significantly lower activation in the right amygdala and in two clusters in the left superior temporal gyrus in the oxytocin administration group compared to the placebo group in response to observing fearful faces. The activation in the conditioned oxytocin group was in between the other two groups for these clusters but did not significantly differ from either group. No group differences were found in the other tasks. Preliminary evidence was found for brain activation of a conditioned oxytocin response; however, despite this trend in the expected direction, the conditioned group did not significantly differ from other groups. Future research should, therefore, investigate the optimal timing of conditioned endocrine responses and study whether the findings generalize to other hormones as well.

Oxytocin Injection Market size, share, and trend analysis indicates growth from USD 873 Million in 2025 to USD 1.64 Billion by 2035, at a CAGR of 6.5%