The oxytocin market is segmented by Indication (Antepartum, Postpartum), Distribution Channel (Hospital Pharmacies, Drug Stores, Online Pharmacies), and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The report offers the value (in USD million) for the above segments.

Abstract: Affectionate touch, which is vital for mental and physical health, was restricted during the Covid-19 pandemic. This study investigated the association between momentary affectionate touch and subjective well-being, as well as salivary oxytocin and cortisol in everyday life during the pandemic. In the first step, we measured anxiety and depression symptoms, loneliness, and attitude toward social touch in a large cross-sectional online survey (N=1,050). From this sample, N=247 participants completed ecologically momentary assessments (EMA) over two days with six daily assessments by answering smartphone-based questions on affectionate touch and momentary mental state and providing concomitant saliva samples for cortisol and oxytocin assessment. Multilevel models showed that on a within-person level, affectionate touch was associated with decreased self-reported anxiety, general burden, stress, and increased oxytocin levels. On a between-person level, affectionate touch was associated with decreased cortisol levels and higher happiness. Moreover, individuals with a positive attitude towards social touch experiencing loneliness reported more mental health problems. Our results suggest that affectionate touch is linked to higher endogenous oxytocin in times of pandemic and lockdown and might buffer stress on a subjective and hormonal level. These findings might have implications for preventing mental burden during social contact restrictions.

G protein-coupled receptors (GPCRs) constitute a vast protein family that encompasses a wide range of functions, including various autocrine, paracrine and endocrine processes. They show considerable diversity at the sequence level, on the basis of which they can be separated into distinct groups . The term clan can be used to describe the GPCRs, as they embrace a group of families for which there are indications of evolutionary relationship, but between which there is no statistically significant similarity in sequence . The currently known clan members include rhodopsin-like GPCRs (Class A, GPCRA), secretin-like GPCRs (Class B, GPCRB), metabotropic glutamate receptor family (Class C, GPCRC), fungal mating pheromone receptors (Class D, GPCRD), cAMP receptors (Class E, GPCRE) and frizzled/smoothened (Class F, GPCRF) . GPCRs are major drug targets, and are consequently the subject of considerable research interest. It has been reported that the repertoire of GPCRs for endogenous ligands consists of approximately 400 receptors in humans and mice . Most GPCRs are identified on the basis of their DNA sequences, rather than the ligand they bind, those that are unmatched to known natural ligands are designated by as orphan GPCRs, or unclassified GPCRs .

Fighting is a major means to compete for limited resources in the wild. After the fight ends, the loser continuously avoids close interaction with the winner and readily flees when confronted. The neural mechanisms that underlie the rapid and long-lasting behavioral changes induced by defeat remains unclear. This study identified oxytocin neurons in the retrochiasmatic supraoptic nucleus and oxytocin-receptor-expressing cells in the anterior subdivision of the ventromedial hypothalamus through a series of functional manipulation and recording experiments. The dataset contains fiber photometry recording data, behavior annotations, and tracking and raw representative histology images. These data reveal the crucial role of oxytocin in social behavior plasticity and expanded the list of regions through which oxytocin can modulate negative social responses.

Oxytocin Injection Market Report 2024, Market Size, Share, Growth, CAGR, Forecast, Revenue, list of Oxytocin Injection Companies (JHP Pharmaceuticals, Agrilab, Novartis, Grindex, Bayer, Pfizer, Hybio Pharmaceutical, Bimeda, GSK, Kepro B.V., Shanghai Hefeng, Renjian Pharmaceutical), Market Segmented by Application (Animal Use, Human Use), by Type (Oxytocin, Carbetocin)

The global oxytocin market expansion is anticipated to achieve USD 193.02 million by 2032 exhibiting a CAGR of 9.3% during the forecast period

Market Overview:

The global injection Oxytocin market is expected to grow at a CAGR of 5.5% from 2022 to 2030. The growth in the market can be attributed to the increasing demand for oxytocin for baby born and cosmetic applications, and rising awareness about the benefits of oxytocin therapy. The global injection oxytocin market is segmented by type, application, and region. By type, the market is divided into injection and freeze-dried injection. By application, it is classified into baby born, cosmetic surgery/aesthetics procedures (such as wrinkle removal), labor induction/augmentation (such as speeding up labor), postpartum hemorrhage prevention & treatment (PPH), other applications (including Autism Spectrum Disorder [ASD], cerebral palsy [CP], chronic obstructive pulmonary disease [COPD]). Geographically, it is analyzed across North America, Latin America, Europe, Asia Pacific, and Middle East & Africa.

Product Definition:

Injection oxytocin is a hormone that is naturally produced by the body. It plays an important role in labor and birth, as well as in breastfeeding. Oxytocin can also be given as a medication to induce labor or to help with breast milk production.

Injection:

Injection oxytocin is a hormone that is produced in the hypothalamus and released into the bloodstream. It is sometimes called "the love hormone" because it helps to create feelings of trust, affection, and security. Injection oxytocin is used to treat conditions such as labor pains, postpartum depression, and autism.

Freeze-dried Injection:

Freeze-dried Injection oxytocin is a form of oxytocin that is freeze-dried. It is used to treat baby born, for domestic, and for others. It provides long-term stability and is easy to administer. It is made from pure oxytocin and has the same effects as oxytocin that is injected.

Application Insights:

For baby born was the largest application segment in the global market and accounted for over 60% of total revenue in 2015. A rise in the number of female reproductive organ donors is expected to boost demand for this drug, which is used as a labor-inducing agent during childbirth. In addition, growing awareness among women regarding pain management during pregnancy will also drive demand over the forecast period. The freeze-dried injection is anticipated to be the fastest growing application segment with a CAGR of around 12% from 2022 to 2030 owing to advantages such as fewer needle pricks and faster absorption by vein compared with other forms of injections. Owing to the increase in adoption rates across various countries including India, China, Japan, Brazil, etc., this drug has become an important tool for treating domestic animals such as horses and dogs along with humans which further boosts its consumption globally.

Regional Analysis:

North America dominated the global market in terms of revenue share in 2019. The region is expected to continue its dominance over the forecast period owing to increasing R&D activities and rising awareness about new technologies for safe delivery. In addition, the presence of key players with extensive research & development capabilities is also likely to support regional growth. Asia Pacific market was valued at USD X million in 2019 and is anticipated to witness lucrative CAGR over the forecast period due to the growing population, improving healthcare infrastructure along with high unmet medical needs, especially regarding premature birth complications are some factors driving regional growth. In Latin America, Oxytocin Injection has been approved by regulatory agencies as a part of national public health programs aimed at reducing the infant mortality rate (IMR).

Growth Factors:

• Increasing demand from pregnant women for the prevention of post-partum hemorrhage.
• Rising prevalence of gynecological disorders such as uterine fibroids, endometriosis, and ovarian cysts.
• Growing awareness about the benefits of oxytocin injection in childbirth and labor induction.
• An increasing number of clinical studies support the use of oxytocin injection in various medical applications.
• Technological advancements have led to the development of new and improved formulations.

Report Scope

A collection of 35 brain maps. Each brain map is a 3D array of values representing properties of the brain at different locations.

Collection description

This collection contains fMRI data from a study in which healthy males received L-DOPA (100 mg + 25 mg carbidopa), intranasal oxytocin (24 IU), or placebo using a double-blind placebo-controlled cross-over design. In each session, participants performed a probabilistic reinforcement learning task with potential rewards for themselves, an anonymous other participant, or no one, during functional magnetic resonance imaging. Computational models of reinforcement learning were used to calculate prediction errors (PEs) and learning rates. Contrasts involve the factors drug (L-DOPA, oxytocin, placebo) and recipient (self, other, no one).

(Note that paper links to https://identifiers.org/neurovault.collection:13141, but this collection was accidentally deleted.)

Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies. Although studies have shown increased cerebrospinal fluid (CSF) OT levels following IN administration, this does not unequivocably demonstrate that the peripherally administered OT is entering the CSF. For example, it has been suggested that peripheral delivery of OT could lead to central release of endogenous OT. It is also unknown whether the IN route provides for more efficient entry of the peptide into the CSF compared to the intravenous (IV) route, which requires blood-brain barrier penetration. To address these questions, we developed a sensitive and specific quantitative mass spectrometry assay that distinguishes labeled (d5-deuterated) from endogenous (d0) OT. We administered d5 OT (80 IU) to six nonhuman primates via IN and IV routes as well as IN saline as a control condition. We measured plasma and CSF concentrations of administered and endogenous OT before (t=0) and after (t=10, 20, 30, 45 and 60?min) d5 OT dosing. We demonstrate CSF penetrance of d5, exogenous OT delivered by IN and IV administration. Peripheral administration of d5 OT did not lead to increased d0, endogenous OT in the CSF. This suggests that peripheral administration of OT does not lead to central release of endogenous OT. We also did not find that IN administration offered an advantage compared to IV administration with respect to achieving greater CSF concentrations of OT.

The table contains 26 products whose active ingredient are classified under the same pharmacologic class Oxytocin [CS].

Global Oxytocin Injection Market size is projected to grow at a CAGR of 5.4% during the forecast period. The demand for oxytocin injections has been on an upward trend due to their ability in reducing postpartum bleeding and pain as well as improving milk production.

Oxytocin injects are used primarily in animals such as horses and cows for reproductive purposes. They can also be used in humans for postpartum hemorrhage or uterine atony prevention after childbirth or abortion procedures, breastfeeding difficulties including insufficient lactation, fibrocystic mastitis, and Ovarian Cysts.

On the basis of Type, the market is segmented into Oxytocin, Carbetocin.

Oxytocin:

Oxytocin is a hormone that helps in triggering uterine contractions during childbirth and post-delivery. It also plays a key role in initiating the milk flow from the mammary glands to breastfeed babies. Oxytocin injection is a synthetic version of oxytocin, which can be used by women going through labor pain to reduce the pain, augment labor and regulate delivery.

Carbetocin:

Carbetocin is a synthetic drug, which helps in reducing postpartum bleeding and strengthening the uterus. It is an agonist of oxytocin and induces contractions to prevent or control excessive bleeding after delivery. Carbetocin injection can be used for treatment prior to childbirth as well as the uterine contraction during labor pain when oxytocic drugs are not working effectively, such as delayed or obstructed labor cases.

On the basis of Application, the market is segmented into Animal Use, Human Use.

Animal Use:

Oxytocin Injection is widely used in animal husbandry applications. It helps to maintain the health of animals by stimulating milk production and reproduction while increasing growth rate and meat yield. The increased demand for high-quality food products has fueled the growth of this market. Additionally, there are some other factors driving the use of oxytocin injection in animal husbandry applications such as its ability to stimulate uterine contractions during labor, control bleeding after birth or abortion, increase stimulation before mating, etc.

Human Use:

Oxytocin injection is used as a medicine to induce labor and improve the contraction of the uterus during delivery. It can also help in controlling bleeding after childbirth (postpartum hemorrhage). It works by directly stimulating contractions of uterine muscles which helps in the childbirth process.

On the basis of Region, the market is segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa.

As per the US Department of Agriculture, more than 50% of beef cattle are injected with oxytocin at some point during their life cycle. This has led to a significant rise in demand for the drug among farmers and ranchers across states like California, Texas, Nebraska, etc., where livestock farming is very popular. The growing population in Brazil, Mexico, and Argentina has increased demand for dairy products leading to a rise in animal husbandry as well as livestock farming. This will increase the need for both natural and synthetic hormones among farmers, further propelling demand from this region over the forecast period. The European market is expected to witness healthy growth during the forecast period, owing to factors such as increasing obesity rates and rising demand for oxytocin in veterinary applications.

Growth Factors For Global Oxytocin Injection Market:

Some of the factors that are expected to drive the global oxytocin injection market include increasing demand for pain management and development. In addition, the increasing geriatric population due to the rising prevalence of diseases such as osteoarthritis and rheumatoid arthritis is also expected to fuel the global oxytocin injection market growth.

Report Scope

Injection Oxytocin Sales Market is expected to increase at a CAGR of 3 to 5 percent, from its estimated valuation of USD XX Million by 2031

dataset for Van Cappellen, P., Way, B., Isgett, S. F., & Fredrickson, B. L. (in press). Effects of oxytocin administration on spirituality and emotional responses to meditation. Social Cognitive and Affective Neuroscience.

The global oxytocin market is expected to grow at a CAGR of 6.1% from 2024 to 2030.

Standard dopamine therapies for schizophrenia are not efficacious for negative symptoms of the disease, including asociality. This reduced social behavior may be due to glutamatergic dysfunction within the amygdala, leading to increased fear and social anxiety. Several studies have demonstrated the prosocial effects of oxytocin in schizophrenia patients. Therefore, this study evaluates the effect of subchronic oxytocin on EEG activity in amygdala of mice during performance of the three-chamber social choice and open field tests following acute ketamine as a model of glutamatergic dysfunction. Oxytocin did not restore social deficits introduced by ketamine but did significantly increase sociality in comparison to the control group. Ketamine had no effect on time spent in the center during the open field trials, whereas oxytocin increased overall center time across all groups, suggesting a reduction in anxiety. Amygdala activity was consistent across all drug groups during social and nonsocial behavioral trials. However, oxytocin reduced overall amygdala EEG power during the two behavioral tasks. Alternatively, ketamine did not significantly affect EEG power throughout the tasks. Decreased EEG power in the amygdala, as caused by oxytocin, may be related to both reduced anxiety and increased social behaviors. Data suggest that separate prosocial and social anxiety pathways may mediate social preference.

Oxytocin Market is growing at a good pace & it is estimated that the market will gain huge shares in the forecasted period

The table includes 68 products with the active ingredient Oxytocin.

27 Yemen import shipment records of Oxytocin with prices, volume & current Buyer’s suppliers relationships based on actual Yemen import trade database.