According to latest figures, the Chinese population decreased by 1.39 million to around 1.408 billion people in 2024. After decades of rapid growth, China arrived at the turning point of its demographic development in 2022, which was earlier than expected. The annual population decrease is estimated to remain at moderate levels until around 2030 but to accelerate thereafter. Population development in China China had for a long time been the country with the largest population worldwide, but according to UN estimates, it has been overtaken by India in 2023. As the population in India is still growing, the country is very likely to remain being home of the largest population on earth in the near future. Due to several mechanisms put into place by the Chinese government as well as changing circumstances in the working and social environment of the Chinese people, population growth has subsided over the past decades, displaying an annual population growth rate of -0.1 percent in 2024. Nevertheless, compared to the world population in total, China held a share of about 17 percent of the overall global population in 2024. China's aging population In terms of demographic developments, the birth control efforts of the Chinese government had considerable effects on the demographic pyramid in China. Upon closer examination of the age distribution, a clear trend of an aging population becomes visible. In order to curb the negative effects of an aging population, the Chinese government abolished the one-child policy in 2015, which had been in effect since 1979, and introduced a three-child policy in May 2021. However, many Chinese parents nowadays are reluctant to have a second or third child, as is the case in most of the developed countries in the world. The number of births in China varied in the years following the abolishment of the one-child policy, but did not increase considerably. Among the reasons most prominent for parents not having more children are the rising living costs and costs for child care, growing work pressure, a growing trend towards self-realization and individualism, and changing social behaviors.

About this dataset

Context

The dataset tabulates the China population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of China across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2023, the population of China was 1,282, a 0.71% increase year-by-year from 2022. Previously, in 2022, China population was 1,273, a decline of 0.70% compared to a population of 1,282 in 2021. Over the last 20 plus years, between 2000 and 2023, population of China increased by 120. In this period, the peak population was 1,289 in the year 2020. The numbers suggest that the population has already reached its peak and is showing a trend of decline. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2023

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2023)
• Population: The population for the specific year for the China is shown in this column.
• Year on Year Change: This column displays the change in China population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for China Population by Year. You can refer the same here

The graph shows the population growth in China from 2000 to 2024. In 2024, the Chinese population decreased by about 0.1 percent or 1.39 million to around 1.408 billion people. Declining population growth in China Due to strict birth control measures by the Chinese government as well as changing family and work situations of the Chinese people, population growth has subsided over the past decades. Although the gradual abolition of the one-child policy from 2014 on led to temporarily higher birth figures, growth rates further decreased in recent years. As of 2024, leading countries in population growth could almost exclusively be found on the African continent and the Arabian Peninsula. Nevertheless, as of mid 2024, Asia ranked first by a wide margin among the continents in terms of absolute population. Future development of Chinese population The Chinese population reached a maximum of 1,412.6 million people in 2021 but decreased by 850,000 in 2022 and another 2.08 million in 2023. Until 2022, China had still ranked the world’s most populous country, but it was overtaken by India in 2023. Apart from the population decrease, a clear growth trend in Chinese cities is visible. By 2024, around 67 percent of Chinese people lived in urban areas, compared to merely 36 percent in 2000.

In 2023, about ***** million people in China were estimated by the UN to be at a working age between 15 and 64 years. After a steep increase in the second half of the 20th century, the size of the working-age population reached a turning point in 2015 and figures started to decrease thereafter. Changes in the working-age population China's demographic development is characterized by a rapid change from a high fertility rate to a low one. This has caused the development of an arc shaped graph of the working age population: quickly increasing numbers before 2010, a gradual turn with a minor second peak until around 2027, and a steep decline thereafter. The expected second maximum of the graph results from the abolishment of birth control measures after 2010, which proved less successful in increasing birth figures than expected. The same turn can be seen in the number of people eligible for work, with an accelerated downturn in the years of the coronavirus pandemic, where many people left the labor force. It is very likely that the size of the labor force will rebound slightly in the upcoming years, but the extent of the rebound, which parallels the second maximum of the working age population, might be limited. China's labor market China's labor market was once defined by its abundant and cheap labor force, but competition for talent has been getting increasingly tense in recent years. This development is very likely to further intensify and extend itself into the less skilled ranks of the labor market. As the number of people who fall within the retirement age group is increasing and adding to the burden on the economy, steps to keep labor participation high are necessary. Raising the retirement age and providing incentives to stay in the labor force, are measures being implemented by Chinese government. Strategies to increase labor productivity would be ideal to mitigate the pressure on the Chinese economy, however, realizing such strategies is challenging.

About this dataset

Context

The dataset tabulates the China population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of China across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2022, the population of China was 1,273, a 0.55% decrease year-by-year from 2021. Previously, in 2021, China population was 1,280, a decline of 0.62% compared to a population of 1,288 in 2020. Over the last 20 plus years, between 2000 and 2022, population of China increased by 111. In this period, the peak population was 1,288 in the year 2020. The numbers suggest that the population has already reached its peak and is showing a trend of decline. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2022

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2022)
• Population: The population for the specific year for the China is shown in this column.
• Year on Year Change: This column displays the change in China population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for China Population by Year. You can refer the same here

About this dataset

Context

The dataset tabulates the China town population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of China town across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2023, the population of China town was 4,568, a 0.88% increase year-by-year from 2022. Previously, in 2022, China town population was 4,528, an increase of 1.21% compared to a population of 4,474 in 2021. Over the last 20 plus years, between 2000 and 2023, population of China town increased by 461. In this period, the peak population was 4,568 in the year 2023. The numbers suggest that the population has not reached its peak yet and is showing a trend of further growth. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2023

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2023)
• Population: The population for the specific year for the China town is shown in this column.
• Year on Year Change: This column displays the change in China town population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for China town Population by Year. You can refer the same here

Total current population for China in 2025 is 1,424,381,924, a 0.06% decline from 2024.

<ul style='margin-top:20px;'>

<li>Total population for China in 2024 was <strong>1,425,178,782</strong>, a <strong>1.03% increase</strong> from 2023.</li>
<li>Total population for China in 2023 was <strong>1,410,710,000</strong>, a <strong>0.1% decline</strong> from 2022.</li>
<li>Total population for China in 2022 was <strong>1,412,175,000</strong>, a <strong>0.01% decline</strong> from 2021.</li>
</ul>Total population is based on the de facto definition of population, which counts all residents regardless of legal status or citizenship. The values shown are midyear estimates.

About this dataset

Context

The dataset tabulates the China Grove population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of China Grove across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2023, the population of China Grove was 4,572, a 1.17% increase year-by-year from 2022. Previously, in 2022, China Grove population was 4,519, an increase of 0.96% compared to a population of 4,476 in 2021. Over the last 20 plus years, between 2000 and 2023, population of China Grove increased by 876. In this period, the peak population was 4,572 in the year 2023. The numbers suggest that the population has not reached its peak yet and is showing a trend of further growth. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2023

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2023)
• Population: The population for the specific year for the China Grove is shown in this column.
• Year on Year Change: This column displays the change in China Grove population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for China Grove Population by Year. You can refer the same here

In the world's most populous country, life expectancy has been continuously rising over the last decades, benefitting greatly from China's economic ascendance. In 2022, average life expectancy at birth in China reached about 78.6 years. Life expectancy at birth Life expectancy at birth refers to the average number of years a group of people born in the same year would live, assuming constant mortality rates. San Marino and Monaco had the highest life expectancy at birth, while China had reached a life expectancy above global average. People who were born in San Marino or Monaco in 2023 had a life expectancy of approximately 87 years or 86 years on average respectively. Demographic development in China Whereas average life expectancy at birth has been growing steadily, birth rates in China have been experiencing a slowdown. In 2024, about 6.77 babies had been born per 1,000 women in China, the second lowest point in the recent decade. As a result of low fertility rates and the extended life expectancy in China, the share of elderly people had been rising rapidly. The number of Chinese population aged 60 and older had more than doubled over the past three decades and is projected to reach its peak at 504 million in 2050. People aged 60 and older have been estimated to account for approximately one fourth of China’s total population by 2030, indicating a sharp climb from just around 13 percent in 2010. In order to pinpoint this massive shift in the age pyramid of China, an important indicator for measuring the pressure of aging population on productive population may be consulted. The old-age dependency ratio in China was expected to reach 52.3 percent in 2050.

As of 2023, the bulk of the Chinese population was aged between 25 and 59 years, amounting to around half of the population. A breakdown of the population by broad age groups reveals that around 61.3 percent of the total population was in working age between 16 and 59 years in 2023. Age cohorts below 25 years were considerably smaller, although there was a slight growth trend in recent years. Population development in China Population development in China over the past decades has been strongly influenced by political and economic factors. After a time of high fertility rates during the Maoist regime, China introduced birth-control measures in the 1970s, including the so-called one-child policy. The fertility rate dropped accordingly from around six children per woman in the 1960s to below two at the end of the 20th century. At the same time, life expectancy increased consistently. In the face of a rapidly aging society, the government gradually lifted the one-child policy after 2012, finally arriving at a three-child policy in 2021. However, like in most other developed countries nowadays, people in China are reluctant to have more than one or two children due to high costs of living and education, as well as changed social norms and private values. China’s top-heavy age pyramid The above-mentioned developments are clearly reflected in the Chinese age pyramid. The age cohorts between 30 and 39 years are the last two larger age cohorts. The cohorts between 15 and 24, which now enter childbearing age, are decisively smaller, which will have a negative effect on the number of births in the coming decade. When looking at a gender distribution of the population pyramid, a considerable gender gap among the younger age cohorts becomes visible, leaving even less room for growth in birth figures.

In 2020, about 17.9 percent of the population in China had been 60 years and older. This share is growing rapidly and was estimated to reach 40 percent by 2050. China's aging population With China’s boomer generation growing old and life expectancy increasing at the same time, the number of people at an age of 60 or above nearly doubled between 2000 and 2020 and reached around 255 million. This development is even more pronounced for the age group of 80 and above, which nearly tripled and is expected to reach a size of roughly 132 million in 2050, up from only 32 million in 2020. At the same time, the share of the working-age population is forecasted to decrease gradually from 64 percent of the total population in 2020 to around 50 percent in 2050, which could pose a heavy economic strain on the social security system. The old-age dependency ratio, which denotes the relation of the old-age to the working-age population, is estimated to grow from 18.2 percent in 2020 to more than 50 percent in 2050, implying that by then, statistically, two working-age adults would have to support one elderly. Strain on the social security net During the last 15 years, China's government has successfully increased the coverage of the pension insurance and health insurance. Today, most of the people are covered by some kind of social insurance. Conditions in the pension system are generous, with a regular retirement age for males at 60 years and women at 50 or 55. With the number of retirees increasing quickly, the social insurance system is now under pressure. From an economic point of view, improving the productivity of China's economy would be the primary choice for mitigating alleged inconsistencies of the system. However, without increasing the burden on the working people while tightening payment conditions, balancing the social security net could prove to be challenging.

About this dataset

Context

The dataset tabulates the China township population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of China township across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2023, the population of China township was 3,519, a 0.34% increase year-by-year from 2022. Previously, in 2022, China township population was 3,507, a decline of 0% compared to a population of 3,507 in 2021. Over the last 20 plus years, between 2000 and 2023, population of China township increased by 157. In this period, the peak population was 3,692 in the year 2007. The numbers suggest that the population has already reached its peak and is showing a trend of decline. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2023

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2023)
• Population: The population for the specific year for the China township is shown in this column.
• Year on Year Change: This column displays the change in China township population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for China township Population by Year. You can refer the same here

China: Internet users, percent of population: The latest value from 2023 is 77.48 percent, an increase from 75.61 percent in 2022. In comparison, the world average is 87.67 percent, based on data from 59 countries. Historically, the average for China from 1990 to 2023 is 26.35 percent. The minimum value, 0 percent, was reached in 1990 while the maximum of 77.48 percent was recorded in 2023.

China: Population density, in people per sq. mile: The latest value from is people per sq. mile, unavailable from people per sq. mile in . In comparison, the world average is 0 people per sq. mile, based on data from countries. Historically, the average for China from to is people per sq. mile. The minimum value, people per sq. mile, was reached in while the maximum of people per sq. mile was recorded in .

In 2023, China's labor force amounted to approximately 772.2 million people. The labor force in China indicated a general decreasing trend in recent years. As both the size of the population in working age and the share of the population participating in the labor market are declining, this downward trend will most likely persist in the foreseeable future. A country’s labor force is defined as the total number of employable people and incorporates both the employed and the unemployed population. Population challenges for China One of the reasons for the shrinking labor force is the Chinese one-child policy, which had been in effect for nearly 40 years, until it was revoked in 2016. The controversial policy was intended to improve people’s living standards and optimize resource distribution through controlling the size of China’s expanding population. Nonetheless, the policy also led to negative impacts on the labor market, pension system and other societal aspects. Today, China is becoming an aging society. The increase of elderly people and the lack of young people will become a big challenge for China in this century. Employment in China Despite the slowing down of economic growth, China’s unemployment rate has sustained a relatively low rate. Complete production chains and a well-educated labor force make China’s labor market one of the most attractive in the world. Working conditions and salaries in China have also improved significantly over the past years. Due to China’s leading position in terms of talent in the technology industry, the country is now attracting investment from some of the world’s leading companies in the high-tech sector.

China: Percent urban population: The latest value from 2023 is 64.57 percent, an increase from 63.56 percent in 2022. In comparison, the world average is 61.36 percent, based on data from 196 countries. Historically, the average for China from 1960 to 2023 is 32.82 percent. The minimum value, 16.2 percent, was reached in 1960 while the maximum of 64.57 percent was recorded in 2023.

China: Demographic pressures, 0 (low) - 10 (high): The latest value from 2024 is 6.2 index points, a decline from 6.5 index points in 2023. In comparison, the world average is 5.80 index points, based on data from 176 countries. Historically, the average for China from 2007 to 2024 is 7.26 index points. The minimum value, 5.6 index points, was reached in 2020 while the maximum of 9 index points was recorded in 2009.

Background: The rivaroxaban dose regimen for patients with nonvalvular atrial fibrillation (NVAF) is complex in Asia. Given the high interindividual variability and the risk of bleeding caused by rivaroxaban in Asians, the influencing factors and the relationship between outlier biomarkers and bleeding events need exploration.Methods: The integrated pharmacokinetics (PK)/pharmacodynamics (PD) models were characterized based on rich PK/PD data from 304 healthy volunteers and sparse PD [anti-factor Xa activity (anti-Xa) and prothrombin (PT)] data from 223 patients with NVAF. The correlations between PD biomarkers and clinically relevant bleedings in 1 year were explored. The final integrated PK/PD model was used to evaluate the influence of dosage and individual covariates on PD parameters.Results: A two-compartment, linear model with sequential zero-order and first-order absorption was adopted. The dose-specific relative bioavailability (F1), diet status, creatinine clearance, and body mass index (BMI) improved the model fit. The apparent systemic clearance was 7.39 L/h, and the central and peripheral volumes were 10.9 and 50.9 L, respectively. The linear direct-effects model with shape factor plus the additive (and/or proportional) error model described the correlation between anti-Xa/PT and plasma concentration. Bodyweight, total cholesterol (TCHO), and diet status were selected as the covariates of the anti-Xa/PT model. Anti-Xa was more sensitive to the increase in rivaroxaban exposure compared with PT. An elevated bleeding tendency was seen with higher peak anti-Xa and PT. For a typical Chinese patient, the peak anti-Xa value (median (5%–95% PI)) of 20 and 15 mg were 309 ng/ml (139–597 ng/ml) and 296 ng/ml (138–604 ng/ml), both median values were within the expected range. For patients with CrCL 30–49 ml/min, the median peak anti-Xa with recommended 10 mg other than 15 mg were within the expected range.Conclusion: Fixed doses of rivaroxaban could be prescribed for patients with NVAF without adjustment for bodyweight, BMI, and TCHO. Randomized studies should be performed to evaluate the efficacy and safety of low-dose rivaroxaban in Chinese patients with NVAF.

About this dataset

Context

The dataset tabulates the East China township population over the last 20 plus years. It lists the population for each year, along with the year on year change in population, as well as the change in percentage terms for each year. The dataset can be utilized to understand the population change of East China township across the last two decades. For example, using this dataset, we can identify if the population is declining or increasing. If there is a change, when the population peaked, or if it is still growing and has not reached its peak. We can also compare the trend with the overall trend of United States population over the same period of time.

Key observations

In 2023, the population of East China township was 3,648, a 0.44% decrease year-by-year from 2022. Previously, in 2022, East China township population was 3,664, a decline of 0.84% compared to a population of 3,695 in 2021. Over the last 20 plus years, between 2000 and 2023, population of East China township increased by 12. In this period, the peak population was 3,865 in the year 2007. The numbers suggest that the population has already reached its peak and is showing a trend of decline. Source: U.S. Census Bureau Population Estimates Program (PEP).

Content

When available, the data consists of estimates from the U.S. Census Bureau Population Estimates Program (PEP).

Data Coverage:

• From 2000 to 2023

Variables / Data Columns

• Year: This column displays the data year (Measured annually and for years 2000 to 2023)
• Population: The population for the specific year for the East China township is shown in this column.
• Year on Year Change: This column displays the change in East China township population for each year compared to the previous year.
• Change in Percent: This column displays the year on year change as a percentage. Please note that the sum of all percentages may not equal one due to rounding of values.

Good to know

Margin of Error

Data in the dataset are based on the estimates and are subject to sampling variability and thus a margin of error. Neilsberg Research recommends using caution when presening these estimates in your research.

Custom data

If you do need custom data for any of your research project, report or presentation, you can contact our research staff at research@neilsberg.com for a feasibility of a custom tabulation on a fee-for-service basis.

Inspiration

Neilsberg Research Team curates, analyze and publishes demographics and economic data from a variety of public and proprietary sources, each of which often includes multiple surveys and programs. The large majority of Neilsberg Research aggregated datasets and insights is made available for free download at https://www.neilsberg.com/research/.

Recommended for further research

This dataset is a part of the main dataset for East China township Population by Year. You can refer the same here

Objective: Omadacycline is a new type of aminomethylcycline antibiotic, having a broad antibacterial spectrum. But the pharmacokinetic characteristics and safety profile of the Chinese population remain unknown. It is also unclear whether the US-approved treatment regimen is applicable for the Chinese population.Methods: In a randomized, double-blinded, placebo-controlled dose-escalated trial, the pharmacokinetics of omadacycline was evaluated by a non-compartmental and compartmental model. Monte Carlo simulations were performed using the pharmacokinetic data from the Chinese population to evaluate the probability of target attainment (PTA) and the cumulative fraction of response (CFR) of the US FDA-approved dose regimen.Results: The three-compartment model successfully described the rapid distribution and slow elimination of omadacycline after the intravenous infusion (i.v.). The double-peak concentration-time curve of the oral absorption (p.o.) was explained by the two-compartment model with two absorption compartments. The steady-state AUC of 100 mg omadacycline i.v. and 300 mg omadacycline p. o. were 12.1 and 19.4 mg h/L, respectively. Pharmacokinetics/pharmacodynamics (PK/PD) analysis showed that the omadacycline dosing regimen with a loading dose (200 mg i.v. q24 h, 100 mg i.v. q12 h, 450 mg p. o. q24 h × 2 days or 300 mg p. o. q12 h) and maintenance dose (100 mg i.v. q24 h or 300 mg p. o. q24 h) could cover the main pathogens of the indications acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP): Staphylococcus aureus and Streptococcus pneumoniae. Also, omadacycline had showed a good safety profile in the Chinese population.Conclusions: With the evidence provided, omadacycline could be a novel treatment option to Chinese patients with ABSSSI and CABP.