100+ datasets found
  1. Number of drugs in the R&D pipeline worldwide 2001-2025

    • statista.com
    Updated May 6, 2025
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    Statista (2025). Number of drugs in the R&D pipeline worldwide 2001-2025 [Dataset]. https://www.statista.com/statistics/791263/total-r-and-d-pipeline-size-timeline-worldwide/
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    Dataset updated
    May 6, 2025
    Dataset authored and provided by
    Statistahttp://statista.com/
    Area covered
    Worldwide
    Description

    This statistic shows the total number of drugs in the R&D pipeline worldwide from 2001 to 2025. In 2001, there were ***** drugs in the R&D pipeline, whereas there were ****** drugs in the pipeline in January 2025.

  2. f

    Data from: AMPL: A Data-Driven Modeling Pipeline for Drug Discovery

    • datasetcatalog.nlm.nih.gov
    Updated Apr 16, 2020
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    Weber, Andrew; Tse, Margaret; Calad-Thomson, Stacie; Minnich, Amanda J.; Murad, Neha; Deng, Jason; Madej, Benjamin D.; Allen, Jonathan E.; McLoughlin, Kevin; Ramsundar, Bharath; Rush, Tom; Brase, Jim (2020). AMPL: A Data-Driven Modeling Pipeline for Drug Discovery [Dataset]. https://datasetcatalog.nlm.nih.gov/dataset?q=0000546211
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    Dataset updated
    Apr 16, 2020
    Authors
    Weber, Andrew; Tse, Margaret; Calad-Thomson, Stacie; Minnich, Amanda J.; Murad, Neha; Deng, Jason; Madej, Benjamin D.; Allen, Jonathan E.; McLoughlin, Kevin; Ramsundar, Bharath; Rush, Tom; Brase, Jim
    Description

    One of the key requirements for incorporating machine learning (ML) into the drug discovery process is complete traceability and reproducibility of the model building and evaluation process. With this in mind, we have developed an end-to-end modular and extensible software pipeline for building and sharing ML models that predict key pharma-relevant parameters. The ATOM Modeling PipeLine, or AMPL, extends the functionality of the open source library DeepChem and supports an array of ML and molecular featurization tools. We have benchmarked AMPL on a large collection of pharmaceutical data sets covering a wide range of parameters. Our key findings indicate that traditional molecular fingerprints underperform other feature representation methods. We also find that data set size correlates directly with prediction performance, which points to the need to expand public data sets. Uncertainty quantification can help predict model error, but correlation with error varies considerably between data sets and model types. Our findings point to the need for an extensible pipeline that can be shared to make model building more widely accessible and reproducible. This software is open source and available at: https://github.com/ATOMconsortium/AMPL.

  3. Pharma Data | Global Pharmaceutical Industry | Verified Profiles with...

    • datarade.ai
    Updated Feb 12, 2018
    + more versions
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    Success.ai (2018). Pharma Data | Global Pharmaceutical Industry | Verified Profiles with Business Details | Best Price Guaranteed [Dataset]. https://datarade.ai/data-products/pharma-data-global-pharmaceutical-industry-verified-profi-success-ai
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    .bin, .json, .xml, .csv, .xls, .sql, .txtAvailable download formats
    Dataset updated
    Feb 12, 2018
    Dataset provided by
    Area covered
    Syrian Arab Republic, Aruba, Rwanda, Madagascar, Canada, Liberia, Saint Helena, Mali, Trinidad and Tobago, Marshall Islands
    Description

    Success.ai’s Pharma Data for the Global Pharmaceutical Industry provides a robust dataset tailored for businesses looking to connect with pharmaceutical companies, decision-makers, and key stakeholders worldwide. Covering pharmaceutical manufacturers, research organizations, biotech firms, and distributors, this dataset offers verified SIC codes, firmographic details, and contact information for executives and operational leads.

    With access to over 170 million verified professional profiles and 30 million company profiles, Success.ai ensures your outreach, market research, and business development strategies are driven by reliable, continuously updated, and AI-validated data. Supported by our Best Price Guarantee, this solution is essential for navigating the competitive global pharmaceutical landscape.

    Why Choose Success.ai’s Pharma Data?

    1. Verified Contact Data for Precision Outreach

      • Access verified work emails, phone numbers, and LinkedIn profiles of pharmaceutical executives, R&D leads, compliance officers, and procurement managers.
      • AI-driven validation ensures 99% accuracy, optimizing your campaigns and improving communication efficiency.
    2. Comprehensive Coverage of the Global Pharmaceutical Sector

      • Includes profiles of pharmaceutical companies, biotech firms, contract manufacturing organizations (CMOs), and distributors across North America, Europe, Asia, and other major markets.
      • Gain insights into regional pharmaceutical trends, product pipelines, and market dynamics unique to global markets.
    3. Continuously Updated Datasets

      • Real-time updates reflect leadership changes, mergers, product launches, and regulatory compliance shifts.
      • Stay aligned with the fast-paced pharmaceutical industry to capitalize on emerging opportunities and maintain relevance.
    4. Ethical and Compliant

      • Adheres to GDPR, CCPA, and other global privacy regulations, ensuring responsible use of data and compliance with legal standards.

    Data Highlights:

    • 170M+ Verified Professional Profiles: Engage with decision-makers, R&D specialists, and operational leaders in the pharmaceutical industry worldwide.
    • 30M Company Profiles: Access detailed firmographic data, including company sizes, revenue ranges, and geographic footprints.
    • Verified SIC Codes: Understand industry classifications and product specializations to refine your targeting strategies.
    • Leadership Contact Details: Connect with CEOs, COOs, medical directors, and regulatory managers influencing pharmaceutical operations.

    Key Features of the Dataset:

    1. Decision-Maker Profiles in Pharmaceuticals

      • Identify and engage with professionals overseeing R&D, clinical trials, supply chains, and regulatory compliance.
      • Target leaders responsible for drug development, vendor selection, and market entry strategies.
    2. Advanced Filters for Precision Targeting

      • Filter companies by industry segment (biotech, generic pharmaceuticals, vaccines), geographic location, or revenue size.
      • Tailor campaigns to align with specific needs such as drug pipeline acceleration, production scaling, or market expansion.
    3. SIC Codes and Firmographic Insights

      • Access verified SIC codes and detailed company profiles to understand market focus, operational scale, and specialization areas.
      • Use firmographic data to prioritize high-value targets and align product offerings with market demands.
    4. AI-Driven Enrichment

      • Profiles enriched with actionable data allow for personalized messaging, highlight unique value propositions, and improve engagement outcomes with pharmaceutical stakeholders.

    Strategic Use Cases:

    1. Sales and Lead Generation

      • Offer technology solutions, research tools, or contract services to pharmaceutical manufacturers, R&D facilities, and distribution networks.
      • Build relationships with procurement teams and compliance officers responsible for vendor approvals and operational excellence.
    2. Market Research and Product Development

      • Analyze global pharmaceutical trends, drug approval patterns, and regulatory frameworks to guide product innovation and market entry strategies.
      • Identify high-growth regions and emerging therapeutic areas to focus your resources effectively.
    3. Partnership and Supply Chain Development

      • Connect with pharmaceutical companies seeking contract manufacturing, raw material sourcing, or distribution partnerships.
      • Foster alliances that streamline production, ensure quality, and accelerate time-to-market.
    4. Regulatory Compliance and Risk Mitigation

      • Engage with regulatory officers and compliance managers overseeing adherence to local and international pharmaceutical standards.
      • Present solutions for documentation, reporting, and risk management to ensure compliance and operational efficiency.

    Why Choose Success.ai?

    1. Best Price Guarantee
      ...
  4. d

    MSDF Drug Development Pipeline

    • dknet.org
    • neuinfo.org
    • +1more
    Updated Mar 11, 2025
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    (2025). MSDF Drug Development Pipeline [Dataset]. http://identifiers.org/RRID:SCR_013825
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    Dataset updated
    Mar 11, 2025
    Description

    A database providing information about compounds under investigation for therapeutic use. There are currently 44 compounds on record with 100 compounds in the process of being uploaded to the database.

  5. Pipeline settings for the drug specificity analysis.

    • plos.figshare.com
    xlsx
    Updated Jun 9, 2023
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    Lisa-Katrin Schätzle; Ali Hadizadeh Esfahani; Andreas Schuppert (2023). Pipeline settings for the drug specificity analysis. [Dataset]. http://doi.org/10.1371/journal.pcbi.1007803.s005
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    xlsxAvailable download formats
    Dataset updated
    Jun 9, 2023
    Dataset provided by
    PLOShttp://plos.org/
    Authors
    Lisa-Katrin Schätzle; Ali Hadizadeh Esfahani; Andreas Schuppert
    License

    Attribution 4.0 (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
    License information was derived automatically

    Description

    100 random FORESEE pipelines were chosen and then trained on all 266 available drugs in the GDSC database to predict the patient data sets. (XLSX)

  6. Drug Delivery Infusion Systems - Medical Devices Pipeline Assessment, 2016

    • store.globaldata.com
    Updated Jul 4, 2016
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    GlobalData UK Ltd. (2016). Drug Delivery Infusion Systems - Medical Devices Pipeline Assessment, 2016 [Dataset]. https://store.globaldata.com/report/drug-delivery-infusion-systems-medical-devices-pipeline-assessment-2016/
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    Dataset updated
    Jul 4, 2016
    Dataset provided by
    GlobalDatahttps://www.globaldata.com/
    Authors
    GlobalData UK Ltd.
    License

    https://www.globaldata.com/privacy-policy/https://www.globaldata.com/privacy-policy/

    Time period covered
    2016 - 2020
    Area covered
    Global
    Description

    Drug Delivery Infusion Systems are used to administer medication to a patient in critical care, emergency care, home care and trauma centers. GlobalData's Medical Devices sector report, “Drug Delivery Infusion Systems – Medical Devices Pipeline Assessment, 2016' provides comprehensive information about the Drug Delivery Infusion Systems pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. The Drug Delivery Infusion Systems Pipeline Assessment report provides key information and data related to: Extensive coverage of the Drug Delivery Infusion Systems under development Review details of major pipeline products which include product description, licensing and collaboration details and other developmental activities including pipeline territories, regulatory paths and estimated approval dates Reviews of major players involved in the pipeline product development. Provides key clinical trial data related to ongoing clinical trials such as trial phase, trial status, trial start and end dates, and, the number of trials of the major Drug Delivery Infusion Systems pipeline products. Review of Recent Developments in the segment / industry The Drug Delivery Infusion Systems Pipeline Assessment report enables you to: Access significant competitor information, analysis, and insights to improve your R&D strategies Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage Identify and understand important and diverse types of Drug Delivery Infusion Systems under development Formulate market-entry and market expansion strategies Plan mergers and acquisitions effectively by identifying major players with the most promising pipeline The major companies covered in the “Drug Delivery Infusion Systems – Medical Devices Pipeline Assessment, 2016” report: 410 Medical Innovation, LLC Acuros GmbH AktiVax Inc. Alnylam Pharmaceuticals, Inc. Anesthesia Safety Products, LLC AngioDynamics, Inc. Automedics Medical Systems Baxter International Inc. BioCardia, Inc. Debiotech S.A. Delpor, Inc. Edwards Lifesciences Corporation Eksigent Technologies, LLC Eli Lilly and Company Flowonix Medical, Inc. FluidSynchrony, LLC Fluonic, Inc. Fresenius Kidney Care Imagnus Biomedical Inc. Innovfusion Pte. Ltd. Intarcia Therapeutics, Inc. IRadimed Corporation Ivenix, Inc. LifeMedix, LLC Lynntech, Inc. Medallion Therapeutics, Inc. Medical Device Creations Ltd. MedPrime Technologies Pvt. Ltd. Mercator MedSystems, Inc. Nano Precision Medical NexGen Medical Systems, Inc. Nipro Corporation Owen Mumford Limited Pavmed Inc PRO-IV Medical Ltd. Ratio, Inc. Rice University SteadyMed Therapeutics, Inc. StnDrd Infusion Corporation Tel Aviv University Terumo Corporation ToucheMedical Ltd. Unilife Corporation University of Minnesota University of Southern California Note: Certain sections in the report may be removed or altered based on the availability and relevance of data in relation to the equipment type. The GlobalData Differentiation This report is prepared using data sourced from in-house databases, secondary and primary research by GlobalData's team of industry experts. The data and analysis within this report are driven by GlobalData Medical Equipment (GDME) databases. GlobalData Medical Equipment database gives you comprehensive information required to drive sales, investment and deal-making activity in your business. It includes the following: 15,000+ data tables showing market size across more than 780 medical equipment segments and 15 countries, from 2007 and forecast to 2021 10,000+ primary interviews, conducted annually to ensure data and report quality 1,100+ medical equipment conference reports 2,000+ industry-leading reports per annum, covering growing sectors, market trends, investment opportunities and competitive landscape 600+ analysis reports, covering market and pipeline product analysis, by indication; medical equipment trends and issues, and investment and M&A trends 56,500+ medical equipment company profiles 4,100+ company profiles of medical equipment manufacturers in China and India 2,000+ company profiles of medical equipment manufacturers in Japan 825+ companies’ revenue splits and market shares 1,750+ quarterly and annual medical equipment company financials 700+ medical equipment company SWOTs 19,000+ pipeline product profiles 27,000+ marketed product profiles 33,000+ clinical trials 25,000+ trial investigators 20,600+ product patents 3,700+ reports on companies with products under development 21,500+ reports on deals in the medical equipment industry 1,300+ surgical and diagnostic procedures by therapy area 50+ key healthcare indicators by country For more information or to receive a free demonstration of the service, please visit: GlobalData Medical Custom Requirements Contact us to discuss the areas of your business where you need external input, and we will work with you to identify the strongest way forward to meet your needs. Read More

  7. Drug and Alcohol Management Information System Report (DAMIS)

    • catalog.data.gov
    • data.virginia.gov
    • +1more
    Updated Jul 30, 2025
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    Pipeline and Hazardous Materials Safety Administration (2025). Drug and Alcohol Management Information System Report (DAMIS) [Dataset]. https://catalog.data.gov/dataset/drug-and-alcohol-management-information-system-report-damis
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    Dataset updated
    Jul 30, 2025
    Description

    PHMSA regulations in 49 CFR Part 199 require operators of pipelines, liquefied natural gas plants, and underground natural gas storage facilities to submit data to the DOT DAMIS. Operators with less than 50 covered employees are required to submit once every three years, not annually.

  8. Drug Labels & Side Effects Dataset | 1400+ Records

    • kaggle.com
    zip
    Updated Aug 2, 2025
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    Pratyush Puri (2025). Drug Labels & Side Effects Dataset | 1400+ Records [Dataset]. https://www.kaggle.com/datasets/pratyushpuri/drug-labels-and-side-effects-dataset-1400-records
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    zip(51886 bytes)Available download formats
    Dataset updated
    Aug 2, 2025
    Authors
    Pratyush Puri
    License

    Apache License, v2.0https://www.apache.org/licenses/LICENSE-2.0
    License information was derived automatically

    Description

    Drug Labels and Side Effects Dataset

    Dataset Overview

    This comprehensive pharmaceutical synthetic dataset contains 1,393 records of synthetic drug information with 15 columns, designed for data science projects focusing on healthcare analytics, drug safety analysis, and pharmaceutical research. The dataset simulates real-world pharmaceutical data with appropriate variety and realistic constraints for machine learning applications.

    Dataset Specifications

    AttributeValue
    Total Records1,393
    Total Columns15
    File FormatCSV
    Data TypesMixed (intentional for data cleaning practice)
    DomainPharmaceutical/Healthcare
    Use CaseML Training, Data Analysis, Healthcare Research

    Column Specifications

    Categorical Features

    Column NameData TypeUnique ValuesDescriptionExample Values
    drug_nameObject1,283 uniquePharmaceutical drug names with realistic naming patterns"Loxozepam32", "Amoxparin43", "Virazepam10"
    manufacturerObject10 uniqueMajor pharmaceutical companiesPfizer Inc., AstraZeneca, Johnson & Johnson
    drug_classObject10 uniqueTherapeutic drug classificationsAntibiotic, Analgesic, Antidepressant, Vaccine
    indicationsObject10 uniqueMedical conditions the drug treats"Pain relief", "Bacterial infections", "Depression treatment"
    side_effectsObject434 uniqueCombination of side effects (1-3 per drug)"Nausea, Dizziness", "Headache, Fatigue, Rash"
    administration_routeObject7 uniqueMethod of drug deliveryOral, Intravenous, Topical, Inhalation, Sublingual
    contraindicationsObject10 uniqueMedical warnings for drug usage"Pregnancy", "Heart disease", "Liver disease"
    warningsObject10 uniqueSafety instructions and precautions"Take with food", "Avoid alcohol", "Monitor blood pressure"
    batch_numberObject1,393 uniqueManufacturing batch identifiers"xr691zv", "Ye266vU", "Rm082yX"
    expiry_dateObject782 uniqueDrug expiration dates (YYYY-MM-DD)"2025-12-13", "2027-03-09", "2026-10-06"
    side_effect_severityObject3 uniqueSeverity classificationMild, Moderate, Severe
    approval_statusObject3 uniqueRegulatory approval statusApproved, Pending, Rejected

    Numerical Features

    Column NameData TypeRangeMeanStd DevDescription
    approval_yearFloat/String*1990-20242006.710.0FDA/regulatory approval year
    dosage_mgFloat/String*10-990 mg499.7290.0Medication strength in milligrams
    price_usdFloat/String*$2.32-$499.24$251.12$144.81Drug price in US dollars

    *Intentionally stored as mixed types for data cleaning practice

    Key Statistics

    Manufacturer Distribution

    ManufacturerCountPercentage
    Pfizer Inc.17012.2%
    AstraZeneca~140~10.0%
    Merck & Co.~140~10.0%
    Johnson & Johnson~140~10.0%
    GlaxoSmithKline~140~10.0%
    Others~623~44.8%

    Drug Class Distribution

    Drug ClassCountMost Common
    Anti-inflammatory154
    Antibiotic~140
    Antidepressant~140
    Antiviral~140
    Vaccine~140
    Others~679

    Side Effect Severity

    SeverityCountPercentage
    Severe48835.0%
    Moderate~453~32.5%
    Mild~452~32.5%

    Potential Use Cases

    1. Machine Learning Applications

    • Drug Approval Prediction: Predict approval likelihood based on drug characteristics
    • Price Prediction: Estimate drug pricing using features like class, manufacturer, dosage
    • Side Effect Classification: Classify severity based on drug properties
    • Market Success Analysis: Analyze factors contributing to drug market performance

    2. Data Engineering Projects

    • ETL Pipeline Development: Practice data cleaning and transformation
    • Data Quality Assessment: Implement data validation and quality checks
    • Database Design: Create normalized pharmaceutical database schema
    • Real-time Processing: Stream processing for drug monitoring systems

    3. Business Intelligence

    • Pharmaceutical Market Analysis: Manufacturer market share and competitive analysis
    • Drug Safety Analytics: Side effect patterns and safety profile analysis
    • Regulatory Compliance: Approval trends and regulatory timeline analysis
    • Pricing Strategy: Competitive pricing analysis across drug classes

    Recommended Next Steps

    1. Data Cleaning Pipeline: Implement comprehe...
  9. Prospect Data | Biotechnology & Pharmaceutical Innovators Globally |...

    • datarade.ai
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    Success.ai, Prospect Data | Biotechnology & Pharmaceutical Innovators Globally | Verified Global Profiles from 700M+ Dataset | Best Price Guarantee [Dataset]. https://datarade.ai/data-products/prospect-data-biotechnology-pharmaceutical-innovators-glo-success-ai
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    .bin, .json, .xml, .csv, .xls, .sql, .txtAvailable download formats
    Dataset provided by
    Area covered
    South Georgia and the South Sandwich Islands, Burundi, Congo (Democratic Republic of the), Singapore, Nepal, American Samoa, United States of America, Guernsey, Kazakhstan, New Zealand
    Description

    Success.ai’s Prospect Data for Biotechnology & Pharmaceutical Innovators Globally provides a powerful dataset designed to connect businesses with key players driving innovation in the biotech and pharmaceutical industries worldwide. Covering companies engaged in drug development, biotechnology research, and life sciences innovation, this dataset offers verified profiles, professional histories, work emails, and phone numbers of decision-makers and industry leaders.

    With access to over 700 million verified global profiles and 30 million company profiles, Success.ai ensures your outreach, market research, and partnership efforts are powered by accurate, continuously updated, and AI-validated data. Supported by our Best Price Guarantee, this solution is indispensable for navigating the fast-evolving biotech and pharmaceutical landscape.

    Why Choose Success.ai’s Prospect Data for Biotech and Pharmaceutical Innovators?

    1. Verified Contact Data for Industry Professionals

      • Access verified work emails, phone numbers, and LinkedIn profiles of executives, R&D leads, compliance officers, and procurement managers in the biotech and pharmaceutical sectors.
      • AI-driven validation ensures 99% accuracy, reducing bounce rates and maximizing communication efficiency.
    2. Comprehensive Coverage Across Global Markets

      • Includes profiles of professionals and companies from North America, Europe, Asia-Pacific, and other emerging biotech and pharmaceutical markets.
      • Gain insights into global industry trends, drug development pipelines, and regional innovations.
    3. Continuously Updated Datasets

      • Real-time updates capture leadership changes, research breakthroughs, funding activities, and regulatory compliance updates.
      • Stay ahead of market developments and align your strategies with industry dynamics.
    4. Ethical and Compliant

      • Adheres to GDPR, CCPA, and other global privacy regulations, ensuring responsible use of data and compliance with legal standards.

    Data Highlights:

    • 700M+ Verified Global Profiles: Engage with decision-makers, researchers, and executives in biotech and pharmaceutical industries worldwide.
    • 30M Company Profiles: Access detailed firmographic data, including revenue ranges, research capacities, and operational footprints.
    • Professional Histories: Gain insights into the expertise, career progressions, and roles of professionals driving innovation.
    • Leadership Contact Information: Connect directly with CEOs, R&D heads, regulatory managers, and other key stakeholders shaping the future of life sciences.

    Key Features of the Dataset:

    1. Decision-Maker Profiles in Biotech and Pharmaceuticals

      • Identify and engage with professionals leading research, clinical trials, supply chains, and compliance efforts.
      • Target individuals responsible for strategic decisions in drug development, technology integration, and regulatory adherence.
    2. Advanced Filters for Precision Targeting

      • Filter professionals and companies by industry focus (biotech, generics, vaccines), geographic region, revenue size, or workforce composition.
      • Tailor campaigns to address specific needs, such as drug discovery, manufacturing scalability, or market entry.
    3. Research and Innovation Insights

      • Access data on research priorities, product pipelines, and innovation trends across global biotech and pharmaceutical sectors.
      • Leverage these insights to position your offerings effectively and uncover new opportunities.
    4. AI-Driven Enrichment

      • Profiles enriched with actionable data enable personalized messaging, highlight unique value propositions, and improve engagement outcomes with industry professionals.

    Strategic Use Cases:

    1. Sales and Lead Generation

      • Present products, services, or technologies that accelerate R&D, streamline production, or ensure compliance to biotech and pharmaceutical companies.
      • Build relationships with procurement teams, regulatory managers, and R&D heads managing budgets and resource allocation.
    2. Market Research and Competitive Analysis

      • Analyze global trends in biotechnology and pharmaceuticals to guide product innovation and strategic planning.
      • Benchmark against competitors to identify market gaps, emerging niches, and high-growth opportunities.
    3. Partnership Development and Licensing

      • Engage with organizations seeking strategic partnerships, co-development opportunities, or licensing agreements for drug development.
      • Foster alliances that drive mutual growth and innovation in life sciences.
    4. Regulatory Compliance and Risk Mitigation

      • Connect with compliance officers and legal professionals overseeing regulatory adherence, clinical trials, and product approvals.
      • Offer solutions that simplify compliance reporting, risk management, and quality assurance processes.

    Why Choose Success.ai?

    1. Best Price...
  10. f

    Data from: Active Learning for Drug Design: A Case Study on the Plasma...

    • acs.figshare.com
    txt
    Updated Jun 1, 2023
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    Xiaoyu Ding; Rongrong Cui; Jie Yu; Tiantian Liu; Tingfei Zhu; Dingyan Wang; Jie Chang; Zisheng Fan; Xiaomeng Liu; Kaixian Chen; Hualiang Jiang; Xutong Li; Xiaomin Luo; Mingyue Zheng (2023). Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered Drugs [Dataset]. http://doi.org/10.1021/acs.jmedchem.1c01683.s002
    Explore at:
    txtAvailable download formats
    Dataset updated
    Jun 1, 2023
    Dataset provided by
    ACS Publications
    Authors
    Xiaoyu Ding; Rongrong Cui; Jie Yu; Tiantian Liu; Tingfei Zhu; Dingyan Wang; Jie Chang; Zisheng Fan; Xiaomeng Liu; Kaixian Chen; Hualiang Jiang; Xutong Li; Xiaomin Luo; Mingyue Zheng
    License

    Attribution-NonCommercial 4.0 (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/
    License information was derived automatically

    Description

    The success of artificial intelligence (AI) models has been limited by the requirement of large amounts of high-quality training data, which is just the opposite of the situation in most drug discovery pipelines. Active learning (AL) is a subfield of AI that focuses on algorithms that select the data they need to improve their models. Here, we propose a two-phase AL pipeline and apply it to the prediction of drug oral plasma exposure. In phase I, the AL-based model demonstrated a remarkable capability to sample informative data from a noisy data set, which used only 30% of the training data to yield a prediction capability with an accuracy of 0.856 on an independent test set. In phase II, the AL-based model explored a large diverse chemical space (855K samples) for experimental testing and feedback. Improved accuracy and new highly confident predictions (50K samples) were observed, which suggest that the model’s applicability domain has been significantly expanded.

  11. G

    Clinical Data De-Identification Pipelines Market Research Report 2033

    • growthmarketreports.com
    csv, pdf, pptx
    Updated Oct 7, 2025
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    Growth Market Reports (2025). Clinical Data De-Identification Pipelines Market Research Report 2033 [Dataset]. https://growthmarketreports.com/report/clinical-data-de-identification-pipelines-market
    Explore at:
    pdf, csv, pptxAvailable download formats
    Dataset updated
    Oct 7, 2025
    Dataset authored and provided by
    Growth Market Reports
    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Clinical Data De-Identification Pipelines Market Outlook



    According to our latest research, the global clinical data de-identification pipelines market size reached USD 680 million in 2024, with a robust growth trajectory driven by stringent data privacy regulations and the increasing adoption of digital health records. The market is expected to expand at a CAGR of 15.6% from 2025 to 2033, with the forecasted market size projected to reach USD 2.1 billion by 2033. This growth is primarily attributed to the rising emphasis on patient data security, the proliferation of healthcare data, and the need to facilitate compliant data sharing for research and analytics.




    The rapid digitalization of healthcare systems worldwide has resulted in an unprecedented surge in electronic health records (EHRs), clinical trial data, and patient registries. As healthcare organizations increasingly leverage these vast datasets for research, analytics, and population health management, the risk of data breaches and unauthorized disclosures has escalated. This scenario has intensified the demand for robust clinical data de-identification pipelines, which ensure that personally identifiable information (PII) is systematically removed or masked before data is shared or analyzed. Regulatory frameworks such as HIPAA in the United States, GDPR in Europe, and similar mandates in other regions have made de-identification not just a best practice but a legal requirement, further propelling the adoption of advanced software and services in this market.




    Another significant growth driver for the clinical data de-identification pipelines market is the expanding landscape of clinical research and precision medicine. Pharmaceutical and biotechnology companies, as well as academic and research institutes, are increasingly reliant on large-scale, multi-source datasets to accelerate drug discovery, understand disease mechanisms, and personalize treatment protocols. However, these research initiatives necessitate stringent privacy safeguards to maintain patient confidentiality while enabling meaningful data analysis. The integration of artificial intelligence (AI) and machine learning (ML) technologies into de-identification pipelines has enhanced the accuracy and efficiency of data anonymization processes, thereby supporting the dual objectives of compliance and research innovation.




    Strategic partnerships and collaborations among healthcare providers, technology vendors, and research organizations have also played a pivotal role in shaping the clinical data de-identification pipelines market. Leading technology firms are investing in the development of scalable, interoperable solutions that can seamlessly integrate with existing healthcare IT infrastructure. Moreover, the emergence of cloud-based deployment models has made de-identification solutions more accessible to smaller healthcare entities and research organizations, democratizing access to advanced privacy tools. This trend is particularly pronounced in regions with rapidly evolving healthcare ecosystems, such as Asia Pacific and Latin America, where digital health initiatives are gaining momentum.




    From a regional perspective, North America continues to dominate the clinical data de-identification pipelines market, accounting for the largest revenue share in 2024. This leadership is underpinned by the presence of a mature healthcare IT infrastructure, strong regulatory oversight, and significant investments in clinical research. Europe follows closely, benefiting from stringent data protection laws and a vibrant research community. Meanwhile, Asia Pacific is emerging as the fastest-growing market, fueled by large-scale government initiatives to digitize healthcare, rising awareness about patient privacy, and the increasing participation of regional players in global clinical research networks. Latin America and the Middle East & Africa are also witnessing steady growth, albeit from a smaller base, as healthcare modernization efforts gather pace.





    Component Analysis


    <br /

  12. e

    A phenomics approach for antiviral drug discovery - Images, analysis...

    • data.europa.eu
    • datasetcatalog.nlm.nih.gov
    • +3more
    unknown
    Updated Jun 1, 2021
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    Uppsala universitet (2021). A phenomics approach for antiviral drug discovery - Images, analysis pipelines and feature data [Dataset]. https://data.europa.eu/data/datasets/https-doi-org-10-17044-scilifelab-14188403?locale=sl
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    unknownAvailable download formats
    Dataset updated
    Jun 1, 2021
    Dataset authored and provided by
    Uppsala universitet
    Description

    Abstract:

    The current COVID-19 pandemic has highlighted the need for new and fast methods to identify novel or repurposed therapeutic drugs. Here we present a method for untargeted phenotypic drug screening of virus-infected cells, combining Cell Painting with antibody-based detection of viral infection in a single assay. We designed an image analysis pipeline for segmentation and classification of virus-infected and non-infected cells, followed by extraction of morphological properties. We show that the methodology can successfully capture virus-induced phenotypic signatures of MRC-5 human lung fibroblasts infected with Human coronavirus 229E (CoV-229E). Moreover, we demonstrate that our method can be used in phenotypic drug screening using a panel of nine host- and virus-targeting antivirals. Treatment with effective antiviral compounds reversed the morphological profile of the host cells towards a non-infected state. The method can be used in drug discovery for morphological profiling of novel antiviral compounds on both infected and non-infected cells.

    Screen description: The images are of MRC-5 human lung fibroblasts infected with Human coronavirus 229E (CoV-229E) and treated with a panel of nine host- and virus-targeting antivirals. Cells are labelled with five labels that characterise seven cellular components (from the "Cell Painting" assay) as well as with a Coronavirus pan monoclonal antibody combined with a secondary antibody. This experiment consists of 5 plates. Each plate has 60 wells, and 9 fields of view per well. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file in TIFF format.The channel names (w1-w5) correspond to the following stains: w1 = Hoechst 33342 (HOECHST); w2= Coronavirus pan Monoclonal Antibody (FIPV3-70) + Goat Anti-Mouse IgG H&L secondary antibody (MITO); w3= Wheat Germ Agglutinin/Alexa Fluor 555 + Phalloidin/Alexa Fluor 568 (PHAandWGA); w4= SYTO 14 green (SYTO); w5= Concanavalin A/Alexa Fluor 488 (CONC) Organization of files: 1) Raw image data: - MRC5_HCoV229_Plate1.tar.gz - MRC5_HCoV229_Plate2.tar.gz - MRC5_Plate3.tar.gz - MRC5_Plate4.tar.gz - MRC5_HCoV229_Plate5.tar.gz 2) Image analysis pipelines (CellProfiler 4.0.7): Cell Profiler project with a subset of images to try out the analysis pipeline:- Example_PipelineAndData.tar.gz Quality control, illumination correction and feature extraction pipelines:- AnalysisPipelines.tar.gz

    3) Extracted feature data: - features_MRC5_HCoV229_Plate1.tar.gz - features_MRC5_HCoV229_Plate2.tar.gz- features_MRC5_Plate3.tar.gz- features_MRC5_Plate4.tar.gz- features_MRC5_HCoV229_Plate5.tar.gz Metadata: The file “Metadata_MRC5_HCoV229E_plate1-5.csv“ contains the metadata in CSV format, with the following fields: - Plate_id: corresponds to the experimental plate - Well: well allocation in the 96-well plate - virus: "virus +" when cells are exposed to virus, and "virus -' for non-infected controls- Compound: name of compound - Dose [μM]: dose of compound For full information, see the manuscript to which this data is linked.

  13. E

    Esophageal Cancer Drug Pipeline Analysis Report 2025

    • expertmarketresearch.com
    Updated Dec 13, 2024
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    Claight Corporation (Expert Market Research) (2024). Esophageal Cancer Drug Pipeline Analysis Report 2025 [Dataset]. https://www.expertmarketresearch.com/clinical-trials/esophageal-cancer-drug-pipeline-insight
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    pdf, excel, csv, pptAvailable download formats
    Dataset updated
    Dec 13, 2024
    Dataset authored and provided by
    Claight Corporation (Expert Market Research)
    License

    https://www.expertmarketresearch.com/privacy-policyhttps://www.expertmarketresearch.com/privacy-policy

    Time period covered
    2025 - 2034
    Area covered
    Global
    Measurement technique
    Secondary market research, data modeling, expert interviews
    Dataset funded by
    Claight Corporation (Expert Market Research)
    Description

    The GLOBOCAN database revealed that there were 544,100 esophageal cancer deaths and 604,100 new cases worldwide in 2020, translating to age-standardized incidence and mortality rates of 6.3 and 5.6 per 100,000, respectively. Interestingly, men account for about 70% of instances, and there is a significant gender disparity in frequency worldwide, with men being impacted two to five times more frequently than women.

  14. D

    Clinical Data De-Identification Pipelines Market Research Report 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Oct 1, 2025
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    Dataintelo (2025). Clinical Data De-Identification Pipelines Market Research Report 2033 [Dataset]. https://dataintelo.com/report/clinical-data-de-identification-pipelines-market
    Explore at:
    pdf, csv, pptxAvailable download formats
    Dataset updated
    Oct 1, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Clinical Data De-Identification Pipelines Market Outlook



    According to our latest research, the global clinical data de-identification pipelines market size reached USD 425.8 million in 2024. The market is experiencing robust momentum, with a recorded CAGR of 17.9% driven by the increasing adoption of advanced data privacy solutions across the healthcare sector. By 2033, the market is projected to achieve a value of USD 1,541.3 million, underscoring the escalating need for secure data handling and compliance with stringent regulatory frameworks. The primary growth factor for this sector is the rising volume of healthcare data and the critical necessity to protect patient privacy while enabling data-driven research and innovation.




    The surge in healthcare digitization, coupled with the proliferation of electronic health records (EHRs), has significantly contributed to the growth of the clinical data de-identification pipelines market. Healthcare organizations are increasingly leveraging digital platforms to store, share, and analyze sensitive patient data, which in turn amplifies the risk of data breaches and unauthorized access. This scenario has heightened the demand for robust de-identification solutions, ensuring that personal health information (PHI) is rendered anonymous before being used for research, analytics, or sharing with third parties. Regulatory mandates such as HIPAA in the United States and GDPR in Europe further reinforce the need for effective data de-identification, driving both innovation and adoption in this market.




    Another critical growth driver is the expanding landscape of clinical research and real-world evidence (RWE) generation. Pharmaceutical and biotechnology companies, as well as academic research institutions, rely heavily on access to vast amounts of patient data to accelerate drug development, conduct population health studies, and improve clinical outcomes. However, the sensitive nature of this data necessitates sophisticated de-identification pipelines that can efficiently strip personally identifiable information (PII) while preserving the integrity and utility of the dataset. This balance between data utility and privacy protection is fueling investments in next-generation de-identification software and services, further propelling market expansion.




    The integration of artificial intelligence (AI) and machine learning (ML) technologies into de-identification pipelines is also playing a pivotal role in market growth. Advanced algorithms enable more accurate and automated identification and removal of sensitive information from unstructured clinical narratives, images, and structured datasets. This technological evolution not only enhances the scalability and reliability of de-identification processes but also addresses the growing complexity of healthcare data formats. As a result, organizations can more confidently share anonymized datasets for collaborative research, secondary analytics, and public health monitoring, all while maintaining compliance with global privacy standards.




    From a regional perspective, North America continues to dominate the clinical data de-identification pipelines market, accounting for the largest share in 2024. The region’s leadership is attributed to a robust healthcare infrastructure, widespread adoption of health IT solutions, and stringent regulatory requirements surrounding data privacy. Europe follows closely, propelled by comprehensive data protection laws and strong investments in healthcare digitalization. Meanwhile, the Asia Pacific region is witnessing the fastest growth, driven by burgeoning healthcare IT adoption, increasing clinical research activities, and rising awareness about patient data privacy. Latin America and the Middle East & Africa are emerging as promising markets, supported by gradual improvements in healthcare technology and regulatory frameworks.



    Component Analysis



    The clinical data de-identification pipelines market by component is segmented into software and services, each playing a distinct yet complementary role in the ecosystem. The software segment encompasses a wide array of solutions designed to automate the identification and removal of sensitive data from clinical records, including structured databases, unstructured clinical notes, and even medical images. These software platforms are increasingly leveraging AI and natural language processing (NLP) to enhance accuracy, adaptability, and speed, making them indispensabl

  15. Injectable Drug Delivery - Medical Devices Pipeline Assessment, 2017

    • store.globaldata.com
    Updated Sep 15, 2017
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    GlobalData UK Ltd. (2017). Injectable Drug Delivery - Medical Devices Pipeline Assessment, 2017 [Dataset]. https://store.globaldata.com/report/injectable-drug-delivery-medical-devices-pipeline-assessment-2017/
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    Dataset updated
    Sep 15, 2017
    Dataset provided by
    GlobalDatahttps://www.globaldata.com/
    Authors
    GlobalData UK Ltd.
    License

    https://www.globaldata.com/privacy-policy/https://www.globaldata.com/privacy-policy/

    Time period covered
    2017 - 2021
    Area covered
    Global
    Description

    Injectable Drug Delivery Devices are used for administration of a drug into patient’s blood through a delivery device. GlobalData's Medical Devices sector report, “Injectable Drug Delivery – Medical Devices Pipeline Assessment, 2017" provides comprehensive information about the Injectable Drug Delivery pipeline products with comparative analysis of the products at various stages of development and information about the clinical trials which are in progress. Read More

  16. P

    Global Cancer Vaccines Drug Pipeline Market Global Trade Dynamics 2025-2032

    • statsndata.org
    excel, pdf
    Updated Oct 2025
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    Stats N Data (2025). Global Cancer Vaccines Drug Pipeline Market Global Trade Dynamics 2025-2032 [Dataset]. https://www.statsndata.org/report/cancer-vaccines-drug-pipeline-market-43654
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    pdf, excelAvailable download formats
    Dataset updated
    Oct 2025
    Dataset authored and provided by
    Stats N Data
    License

    https://www.statsndata.org/how-to-orderhttps://www.statsndata.org/how-to-order

    Area covered
    Global
    Description

    The Cancer Vaccines Drug Pipeline market is rapidly evolving as a cornerstone of therapeutic innovation within the oncology landscape. With the global cancer burden continuing to rise, cancer vaccines have emerged as a promising solution to enhance the body's immune response against various cancer types. These vacci

  17. P

    Global NASH Drug Pipeline Market Demand Forecasting 2025-2032

    • statsndata.org
    excel, pdf
    Updated Oct 2025
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    Stats N Data (2025). Global NASH Drug Pipeline Market Demand Forecasting 2025-2032 [Dataset]. https://www.statsndata.org/report/nash-drug-pipeline-market-29411
    Explore at:
    pdf, excelAvailable download formats
    Dataset updated
    Oct 2025
    Dataset authored and provided by
    Stats N Data
    License

    https://www.statsndata.org/how-to-orderhttps://www.statsndata.org/how-to-order

    Area covered
    Global
    Description

    The Non-Alcoholic Steatohepatitis (NASH) Drug Pipeline market is increasingly recognized as a critical area of focus within the pharmaceutical industry. NASH, a progressive liver disease characterized by inflammation and fat accumulation in the liver, has seen a surge in prevalence, primarily linked to rising obesit

  18. Leading pharma contract development and manufacturing companies 2024

    • statista.com
    Updated May 8, 2025
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    Matej Mikulic (2025). Leading pharma contract development and manufacturing companies 2024 [Dataset]. https://www.statista.com/topics/6755/pharmaceutical-research-and-development-randd/
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    Dataset updated
    May 8, 2025
    Dataset provided by
    Statistahttp://statista.com/
    Authors
    Matej Mikulic
    Description

    In 2024, Lonza Group had the highest revenue amounting to over eight billion U.S. dollars, among the world's leading contract development and manufacturing companies. A contract development and manufacturing organization (CDMO) can take over various aspects of a pharmaceutical company, including services ranging from drug development to drug manufacturing.

  19. f

    Data from: MeRgeION: a Multifunctional R Pipeline for Small Molecule...

    • acs.figshare.com
    xlsx
    Updated Jun 2, 2023
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    Youzhong Liu; Yingjie Zhang; Tom Vennekens; Jennifer L. Lippens; Luc Duijsens; Danh Bui-Thi; Kris Laukens; Thomas de Vijlder (2023). MeRgeION: a Multifunctional R Pipeline for Small Molecule LC-MS/MS Data Processing, Searching, and Organizing [Dataset]. http://doi.org/10.1021/acs.analchem.2c04343.s002
    Explore at:
    xlsxAvailable download formats
    Dataset updated
    Jun 2, 2023
    Dataset provided by
    ACS Publications
    Authors
    Youzhong Liu; Yingjie Zhang; Tom Vennekens; Jennifer L. Lippens; Luc Duijsens; Danh Bui-Thi; Kris Laukens; Thomas de Vijlder
    License

    Attribution-NonCommercial 4.0 (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/
    License information was derived automatically

    Description

    Small molecule structure elucidation using tandem mass spectrometry (MS/MS) plays a crucial role in life science, bioanalytical, and pharmaceutical research. There is a pressing need for increased throughput of compound identification and transformation of historical data into information-rich spectral databases. Meanwhile, molecular networking, a recent bioinformatic framework, provides global displays and system-level understanding of complex LC-MS/MS data sets. Herein we present meRgeION, a multifunctional, modular, and flexible R-based toolbox to streamline spectral database building, automated structural elucidation, and molecular networking. The toolbox offers diverse tuning parameters and the possibility to combine various algorithms in the same pipeline. As an open-source R package, meRgeION is ideally suited for building spectral databases and molecular networks from privacy-sensitive and preliminary data. Using meRgeION, we have created an integrated spectral database covering diverse pharmaceutical compounds that was successfully applied to annotate drug-related metabolites from a published nontargeted metabolomics data set as well as reveal the chemical space behind this complex data set through molecular networking. Moreover, the meRgeION-based processing workflow has demonstrated the usefulness of a spectral library search and molecular networking for pharmaceutical forced degradation studies. meRgeION is freely available at: https://github.com/daniellyz/meRgeION2.

  20. D

    Pipeline HCA Mapping Platforms Market Research Report 2033

    • dataintelo.com
    csv, pdf, pptx
    Updated Sep 30, 2025
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    Dataintelo (2025). Pipeline HCA Mapping Platforms Market Research Report 2033 [Dataset]. https://dataintelo.com/report/pipeline-hca-mapping-platforms-market
    Explore at:
    pdf, csv, pptxAvailable download formats
    Dataset updated
    Sep 30, 2025
    Dataset authored and provided by
    Dataintelo
    License

    https://dataintelo.com/privacy-and-policyhttps://dataintelo.com/privacy-and-policy

    Time period covered
    2024 - 2032
    Area covered
    Global
    Description

    Pipeline HCA Mapping Platforms Market Outlook



    According to our latest research, the global Pipeline HCA Mapping Platforms market size reached USD 1.32 billion in 2024, reflecting robust demand for high-content analysis (HCA) technologies in drug discovery and disease research. The market is expected to grow at a CAGR of 9.8% from 2025 to 2033, reaching a projected value of USD 3.04 billion by 2033. This growth is primarily driven by the increasing adoption of high-throughput screening methods, rising investments in pharmaceutical R&D, and the expanding application of HCA mapping in oncology and personalized medicine.




    One of the foremost growth factors propelling the Pipeline HCA Mapping Platforms market is the escalating demand for precision medicine and targeted therapy development. Pharmaceutical and biotechnology companies are increasingly leveraging HCA mapping platforms to accelerate drug discovery processes, identify novel biomarkers, and optimize therapeutic candidates. The ability of these platforms to provide comprehensive cellular insights at high throughput enables researchers to analyze complex biological systems more efficiently. This, in turn, reduces the time and cost associated with traditional experimentation, making HCA mapping platforms an indispensable tool in modern drug development pipelines. The integration of artificial intelligence and machine learning algorithms further enhances the capabilities of these platforms, allowing for automated image analysis and data interpretation, which significantly boosts productivity and accuracy in research settings.




    Another significant growth driver is the surge in oncology and chronic disease research. As cancer and cardiovascular diseases continue to pose substantial health burdens worldwide, there is a growing emphasis on understanding cellular responses to various treatments at a granular level. Pipeline HCA mapping platforms facilitate detailed phenotypic screening and mechanistic studies, enabling researchers to uncover subtle changes in cell morphology and function. The platforms' advanced imaging and data analytics capabilities support the identification of potential drug candidates and the assessment of their efficacy and safety profiles. Furthermore, the expansion of collaborative research initiatives between academia, industry, and contract research organizations (CROs) is fostering the adoption of these platforms, as stakeholders seek to streamline workflows and enhance the reproducibility of experimental outcomes.




    Technological advancements and increasing accessibility of cloud-based deployment models are also catalyzing market growth. Cloud-based HCA mapping platforms offer scalability, remote access, and seamless integration with other laboratory information management systems (LIMS), making them attractive to both large enterprises and small-to-medium research labs. The shift towards cloud-based solutions is particularly pronounced in regions with robust digital infrastructure, enabling real-time data sharing and collaboration across geographically dispersed teams. This trend is complemented by the growing availability of software-as-a-service (SaaS) offerings, which lower the barriers to entry for emerging players and academic institutions. As a result, the market is experiencing a democratization of high-content analysis technologies, fostering innovation and expanding the user base beyond traditional pharmaceutical giants.




    From a regional perspective, North America continues to dominate the Pipeline HCA Mapping Platforms market, accounting for the largest share in 2024, followed by Europe and Asia Pacific. The presence of leading pharmaceutical companies, advanced healthcare infrastructure, and substantial government funding for biomedical research underpin the strong market performance in these regions. Meanwhile, Asia Pacific is witnessing the fastest growth, driven by increasing investments in life sciences, expanding biotech sectors, and rising adoption of cutting-edge research technologies. Latin America and the Middle East & Africa are also emerging as promising markets, supported by gradual improvements in research infrastructure and growing interest in precision medicine. Overall, the global market is characterized by dynamic regional trends, with each geography contributing uniquely to the sector's expansion.



    Component Analysis



    The Pipeline HCA Mapping Platforms market by component is segmented into software and service

Share
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Statista (2025). Number of drugs in the R&D pipeline worldwide 2001-2025 [Dataset]. https://www.statista.com/statistics/791263/total-r-and-d-pipeline-size-timeline-worldwide/
Organization logo

Number of drugs in the R&D pipeline worldwide 2001-2025

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2 scholarly articles cite this dataset (View in Google Scholar)
Dataset updated
May 6, 2025
Dataset authored and provided by
Statistahttp://statista.com/
Area covered
Worldwide
Description

This statistic shows the total number of drugs in the R&D pipeline worldwide from 2001 to 2025. In 2001, there were ***** drugs in the R&D pipeline, whereas there were ****** drugs in the pipeline in January 2025.

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